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Search of human proteins with 38569398
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
(1167 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38569398 integrin, alpha 10 precursor [Homo sapiens] 2356 0.0
gi|52485853 integrin, alpha 11 precursor [Homo sapiens] 935 0.0
gi|31657142 integrin, alpha 1 precursor [Homo sapiens] 717 0.0
gi|116295258 integrin alpha 2 precursor [Homo sapiens] 659 0.0
gi|62548866 integrin, alpha D precursor [Homo sapiens] 403 e-112
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 384 e-106
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] 380 e-105
gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] 380 e-105
gi|34452173 integrin alpha X precursor [Homo sapiens] 358 1e-98
gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] 316 7e-86
gi|148728188 integrin, alpha E precursor [Homo sapiens] 310 7e-84
gi|52485941 integrin, alpha 9 precursor [Homo sapiens] 235 2e-61
gi|67191027 integrin alpha 4 precursor [Homo sapiens] 209 2e-53
gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [... 188 3e-47
gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [... 187 5e-47
gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens] 185 2e-46
gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens] 184 4e-46
gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens] 184 4e-46
gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] 179 2e-44
gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens] 179 2e-44
gi|49170034 integrin, alpha 8 [Homo sapiens] 173 1e-42
gi|56237029 integrin alpha 5 precursor [Homo sapiens] 166 2e-40
gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] 156 1e-37
gi|223468595 integrin alpha-V isoform 2 [Homo sapiens] 149 1e-35
gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] 149 1e-35
gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens] 149 2e-35
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ... 90 1e-17
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 90 1e-17
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 87 1e-16
gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens] 81 5e-15
>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
Length = 1167
Score = 2356 bits (6105), Expect = 0.0
Identities = 1167/1167 (100%), Positives = 1167/1167 (100%)
Query: 1 MELPFVTHLFLPLVFLTGLCSPFNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGA 60
MELPFVTHLFLPLVFLTGLCSPFNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGA
Sbjct: 1 MELPFVTHLFLPLVFLTGLCSPFNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGA 60
Query: 61 PWDGPSGDRRGDVYRCPVGGAHNAPCAKGHLGDYQLGNSSHPAVNMHLGMSLLETDGDGG 120
PWDGPSGDRRGDVYRCPVGGAHNAPCAKGHLGDYQLGNSSHPAVNMHLGMSLLETDGDGG
Sbjct: 61 PWDGPSGDRRGDVYRCPVGGAHNAPCAKGHLGDYQLGNSSHPAVNMHLGMSLLETDGDGG 120
Query: 121 FMACAPLWSRACGSSVFSSGICARVDASFQPQGSLAPTAQRCPTYMDVVIVLDGSNSIYP 180
FMACAPLWSRACGSSVFSSGICARVDASFQPQGSLAPTAQRCPTYMDVVIVLDGSNSIYP
Sbjct: 121 FMACAPLWSRACGSSVFSSGICARVDASFQPQGSLAPTAQRCPTYMDVVIVLDGSNSIYP 180
Query: 181 WSEVQTFLRRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREG 240
WSEVQTFLRRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREG
Sbjct: 181 WSEVQTFLRRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREG 240
Query: 241 RETKTAQAIMVACTEGFSQSHGGRPEAARLLVVVTDGESHDGEELPAALKACEAGRVTRY 300
RETKTAQAIMVACTEGFSQSHGGRPEAARLLVVVTDGESHDGEELPAALKACEAGRVTRY
Sbjct: 241 RETKTAQAIMVACTEGFSQSHGGRPEAARLLVVVTDGESHDGEELPAALKACEAGRVTRY 300
Query: 301 GIAVLGHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGS 360
GIAVLGHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGS
Sbjct: 301 GIAVLGHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGS 360
Query: 361 HAENESSFGLEMSQIGFSTHRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEF 420
HAENESSFGLEMSQIGFSTHRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEF
Sbjct: 361 HAENESSFGLEMSQIGFSTHRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEF 420
Query: 421 PPALQNHAAYLGYSVSSMLLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSLQGE 480
PPALQNHAAYLGYSVSSMLLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSLQGE
Sbjct: 421 PPALQNHAAYLGYSVSSMLLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSLQGE 480
Query: 481 QIGSYFGSELCPLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQ 540
QIGSYFGSELCPLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQ
Sbjct: 481 QIGSYFGSELCPLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQ 540
Query: 541 PEPPQDARFGFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIA 600
PEPPQDARFGFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIA
Sbjct: 541 PEPPQDARFGFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIA 600
Query: 601 AASMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAIS 660
AASMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAIS
Sbjct: 601 AASMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAIS 660
Query: 661 VVQRDCRRRGQEAVCLTAALCFQVTSRTPGRWDHQFYMRFTASLDEWTAGARAAFDGSGQ 720
VVQRDCRRRGQEAVCLTAALCFQVTSRTPGRWDHQFYMRFTASLDEWTAGARAAFDGSGQ
Sbjct: 661 VVQRDCRRRGQEAVCLTAALCFQVTSRTPGRWDHQFYMRFTASLDEWTAGARAAFDGSGQ 720
Query: 721 RLSPRRLRLSVGNVTCEQLHFHVLDTSDYLRPVALTVTFALDNTTKPGPVLNEGSPTSIQ 780
RLSPRRLRLSVGNVTCEQLHFHVLDTSDYLRPVALTVTFALDNTTKPGPVLNEGSPTSIQ
Sbjct: 721 RLSPRRLRLSVGNVTCEQLHFHVLDTSDYLRPVALTVTFALDNTTKPGPVLNEGSPTSIQ 780
Query: 781 KLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKAPFVVRGGRRKVLVSTTLENRKENAYNT 840
KLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKAPFVVRGGRRKVLVSTTLENRKENAYNT
Sbjct: 781 KLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKAPFVVRGGRRKVLVSTTLENRKENAYNT 840
Query: 841 SLSLIFSRNLHLASLTPQRESPIKVECAAPSAHARLCSVGHPVFQTGAKVTFLLEFEFSC 900
SLSLIFSRNLHLASLTPQRESPIKVECAAPSAHARLCSVGHPVFQTGAKVTFLLEFEFSC
Sbjct: 841 SLSLIFSRNLHLASLTPQRESPIKVECAAPSAHARLCSVGHPVFQTGAKVTFLLEFEFSC 900
Query: 901 SSLLSQVFVKLTASSDSLERNGTLQDNTAQTSAYIQYEPHLLFSSESTLHRYEVHPYGTL 960
SSLLSQVFVKLTASSDSLERNGTLQDNTAQTSAYIQYEPHLLFSSESTLHRYEVHPYGTL
Sbjct: 901 SSLLSQVFVKLTASSDSLERNGTLQDNTAQTSAYIQYEPHLLFSSESTLHRYEVHPYGTL 960
Query: 961 PVGPGPEFKTTLRVQNLGCYVVSGLIISALLPAVAHGGNYFLSLSQVITNNASCIVQNLT 1020
PVGPGPEFKTTLRVQNLGCYVVSGLIISALLPAVAHGGNYFLSLSQVITNNASCIVQNLT
Sbjct: 961 PVGPGPEFKTTLRVQNLGCYVVSGLIISALLPAVAHGGNYFLSLSQVITNNASCIVQNLT 1020
Query: 1021 EPPGPPVHPEELQHTNRLNGSNTQCQVVRCHLGQLAKGTEVSVGLLRLVHNEFFRRAKFK 1080
EPPGPPVHPEELQHTNRLNGSNTQCQVVRCHLGQLAKGTEVSVGLLRLVHNEFFRRAKFK
Sbjct: 1021 EPPGPPVHPEELQHTNRLNGSNTQCQVVRCHLGQLAKGTEVSVGLLRLVHNEFFRRAKFK 1080
Query: 1081 SLTVVSTFELGTEEGSVLQLTEASRWSESLLEVVQTRPILISLWILIGSVLGGLLLLALL 1140
SLTVVSTFELGTEEGSVLQLTEASRWSESLLEVVQTRPILISLWILIGSVLGGLLLLALL
Sbjct: 1081 SLTVVSTFELGTEEGSVLQLTEASRWSESLLEVVQTRPILISLWILIGSVLGGLLLLALL 1140
Query: 1141 VFCLWKLGFFAHKKIPEEEKREEKLEQ 1167
VFCLWKLGFFAHKKIPEEEKREEKLEQ
Sbjct: 1141 VFCLWKLGFFAHKKIPEEEKREEKLEQ 1167
>gi|52485853 integrin, alpha 11 precursor [Homo sapiens]
Length = 1188
Score = 935 bits (2417), Expect = 0.0
Identities = 515/1180 (43%), Positives = 726/1180 (61%), Gaps = 41/1180 (3%)
Query: 1 MELPFVTHLFLPLVFLTGLCSPFNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGA 60
M+LP + L G FN+D PR+ PG A FGY+V QH G +W++VGA
Sbjct: 1 MDLPRGLVVAWALSLWPGFTDTFNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGA 60
Query: 61 PWDGPSGDRRGDVYRCPVGGAHNAPCAKGHLGDYQLGNSSHPAVNMHLGMSLLETDGDGG 120
P + + GDVY+CPV + C K +LG L N S NM LG+SL D
Sbjct: 61 PLETNGYQKTGDVYKCPV---IHGNCTKLNLGRVTLSNVSERKDNMRLGLSLATNPKDNS 117
Query: 121 FMACAPLWSRACGSSVFSSGICARVDASFQPQGSLAPTAQRCPTYMDVVIVLDGSNSIYP 180
F+AC+PLWS CGSS +++G+C+RV+++F+ ++AP QRC TYMD+VIVLDGSNSIYP
Sbjct: 118 FLACSPLWSHECGSSYYTTGMCSRVNSNFRFSKTVAPALQRCQTYMDIVIVLDGSNSIYP 177
Query: 181 WSEVQTFLRRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREG 240
W EVQ FL ++ K +I P QIQVG+VQYGE VHE+ L D+R+ ++VV AA ++ +R G
Sbjct: 178 WVEVQHFLINILKKFYIGPGQIQVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGG 237
Query: 241 RETKTAQAIMVACTEGFSQSHGGRPEAARLLVVVTDGESHDGEELPAALKACEAGRVTRY 300
ET+TA I A +E F + GGR A ++++V+TDGESHD +L ++ E VTRY
Sbjct: 238 TETRTAFGIEFARSEAFQK--GGRKGAKKVMIVITDGESHDSPDLEKVIQQSERDNVTRY 295
Query: 301 GIAVLGHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGS 360
+AVLG+Y RR +P +FL EI+ IASDPD++ FFNVTDEAAL DIVDALGDRIF LEG+
Sbjct: 296 AVAVLGYYNRRGINPETFLNEIKYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGT 355
Query: 361 HAENESSFGLEMSQIGFSTHRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEF 420
+ +NE+SFGLEMSQ GFS+H ++DG+L G VGAYDW G+VL ++ P R + EF
Sbjct: 356 N-KNETSFGLEMSQTGFSSHVVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEF 414
Query: 421 PPALQNHAAYLGYSVSSMLLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSLQGE 480
P L+NH AYLGY+V+S++ R++++GAPRF H GKVI F + + ++ + Q+++G+
Sbjct: 415 PEELKNHGAYLGYTVTSVVSSRQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQ 474
Query: 481 QIGSYFGSELCPLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQ 540
QIGSYFGSE+ +D D DG TDVLLV APM+ + +E G+VYVY + +Q+L GTL+
Sbjct: 475 QIGSYFGSEITSVDIDGDGVTDVLLVGAPMYFN-EGRERGKVYVYEL-RQNLFVYNGTLK 532
Query: 541 PEPP-QDARFGFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRI 599
Q+ARFG ++ ++ DLNQD + DV VGAPLED H GA+Y++HG + + P QRI
Sbjct: 533 DSHSYQNARFGSSIASVRDLNQDSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRI 592
Query: 600 AAASMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAI 659
A+ + L YFG S+ G+LDL+ D L+D+AVGA G A++L SRP+V + SL P I
Sbjct: 593 TASELATGLQYFGCSIHGQLDLNEDGLIDLAVGALGNAVILWSRPVVQINASLHFEPSKI 652
Query: 660 SVVQRDCRRRGQEAVCLTAALCFQVTSRTPGRWDHQFYMRFTASLDEWTAGARAAFDGSG 719
++ RDC+R G++A CL A LCF P +R+ A++DE RA D G
Sbjct: 653 NIFHRDCKRSGRDATCLAAFLCFTPIFLAPHFQTTTVGIRYNATMDERRYTPRAHLDEGG 712
Query: 720 QRLSPRRLRLSVGNVTCEQLHFHVLDTSDYLRPVALTVTFALDNTTKPGPVLNEGSPTSI 779
R + R + LS G CE+++FHVLDT+DY++PV +V ++L++ GP+L++G PT++
Sbjct: 713 DRFTNRAVLLSSGQELCERINFHVLDTADYVKPVTFSVEYSLEDPDH-GPMLDDGWPTTL 771
Query: 780 QKLVPFSKDCGPDNECVTDLVLQVNMDI--------RGSRK--------------APFVV 817
+ VPF C D CV DLVL D+ R RK F++
Sbjct: 772 RVSVPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFII 831
Query: 818 RGGRRKVLVSTTLENRKENAYNTSLSLIFSRNLHLASLTPQRESPIKVECAAPS--AHAR 875
R++V V TLENR ENAY+T L++ S NL ASL + +S +EC +
Sbjct: 832 ESTRQRVAVEATLENRGENAYSTVLNISQSANLQFASLIQKEDSDGSIECVNEERRLQKQ 891
Query: 876 LCSVGHPVFQTGAKVTFLLEFEFSCSSLLSQVFVKLTASSDSLERNGTLQDNTAQTSAYI 935
+C+V +P F+ AKV F L+FEFS S L + ++L A SDS ER+ T +DN A ++
Sbjct: 892 VCNVSYPFFRAKAKVAFRLDFEFSKSIFLHHLEIELAAGSDSNERDSTKEDNVAPLRFHL 951
Query: 936 QYEPHLLFSSESTLHRYEVHPYGTLP--VGPGPEFKTTLRVQNLGCYVVSGLIISALLPA 993
+YE +LF+ S+L YEV P +L G GP F R+QNLG + + G+++ +P
Sbjct: 952 KYEADVLFTRSSSLSHYEVKPNSSLERYDGIGPPFSCIFRIQNLGLFPIHGMMMKITIPI 1011
Query: 994 VAHGGNYFLSLSQVITN--NASC-IVQNLTEPPGPPVHPEELQHTNRLNGSNTQCQVVRC 1050
GN L L +T+ N SC I N TE PV E+L+ +LN SN+ + C
Sbjct: 1012 ATRSGNRLLKLRDFLTDEANTSCNIWGNSTEYRPTPVE-EDLRRAPQLNHSNSDVVSINC 1070
Query: 1051 HLGQLAKGTEVSVGLLRLVHNEFFRRAKFKSLTVVSTFELGTEEGSVLQLTEASRWSESL 1110
++ +L E++ LL + + K+KS+ ++ L + S E + +
Sbjct: 1071 NI-RLVPNQEINFHLLGNLWLRSLKALKYKSMKIMVNAALQRQFHSPFIFREEDPSRQIV 1129
Query: 1111 LEVVQTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFF 1150
E+ + + +WI++GS LGGLLLLALLV LWKLGFF
Sbjct: 1130 FEISKQEDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFF 1169
>gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
Length = 1179
Score = 717 bits (1850), Expect = 0.0
Identities = 428/1182 (36%), Positives = 657/1182 (55%), Gaps = 66/1182 (5%)
Query: 20 CSPFNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGAPWDGPSGDRRGDVYRCPVG 79
C FN+D + F GP E FGY+V Q+ +W+L+G+P G +R GDVY+CPVG
Sbjct: 26 CVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVG 85
Query: 80 GAHNAPCAKGHLG-DYQLGNSSHPAVNMHLGMSLLETDGDGGFMACAPLWSRACGSSVFS 138
+ PC K L + + N + NM G +L+ T+ +GGF+AC PL++ CG ++
Sbjct: 86 RGESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLV-TNPNGGFLACGPLYAYRCGHLHYT 144
Query: 139 SGICARVDASFQPQGSLAPTAQRCPTYMDVVIVLDGSNSIYPWSEVQTFLRRLVGKLFID 198
+GIC+ V +FQ S+AP Q C T +D+VIVLDGSNSIYPW V FL L+ ++ I
Sbjct: 145 TGICSDVSPTFQVVNSIAPV-QECSTQLDIVIVLDGSNSIYPWDSVTAFLNDLLERMDIG 203
Query: 199 PEQIQVGLVQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREGRETKTAQAIMVACTEGFS 258
P+Q QVG+VQYGE+ HE++L + + EEV+ AAK + +R GR+T TA I A E F+
Sbjct: 204 PKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGIDTARKEAFT 263
Query: 259 QSHGGRPEAARLLVVVTDGESHDGEELPAALKACEAGRVTRYGIAVLGHYLRRQRDPSSF 318
++ G R +++V+VTDGESHD L ++ CE + R+ IA+LG Y R F
Sbjct: 264 EARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKF 323
Query: 319 LREIRTIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGSHAENESSFGLEMSQIGFS 378
+ EI++IAS+P E+ FFNV+DE AL IV LG+RIF LE + ++ +SF +EMSQ GFS
Sbjct: 324 VEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTGFS 383
Query: 379 THRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEFPPALQNHAAYLGYSVSSM 438
H +D ++ G VGAYDW G+V+ + + P E + A+YLGY+V+S
Sbjct: 384 AHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSA 443
Query: 439 LLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSLQGEQIGSYFGSELCPLDTDRD 498
G L+++G PR+ H G+VI +++ +DG +++ Q+L GEQIGSYFGS L D D+D
Sbjct: 444 TASSGDVLYIAGQPRYNHTGQVIIYRM-EDGNIKILQTLSGEQIGSYFGSILTTTDIDKD 502
Query: 499 GTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQP----------------- 541
TD+LLV APM++G + +E G+VYVY + Q+ Q +L+P
Sbjct: 503 SNTDILLVGAPMYMGTEKEEQGKVYVYAL-NQTRFEYQMSLEPIKQTCCSSRQHNSCTTE 561
Query: 542 --EPPQDARFGFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRI 599
P ARFG A+ A+ DLN DGF D+ +GAPLED H GA+Y+YHG+ +R AQRI
Sbjct: 562 NKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKEYAQRI 621
Query: 600 AAASMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAI 659
+ L +FG+S+ G +DL+GD L DV +G G A L SR + + ++ P +
Sbjct: 622 PSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKV 681
Query: 660 SVVQRDCRRRGQEAVCLTAALCFQVTSRTPGRWDHQFYMRFTASLDEWTAGARAAFDGSG 719
++ +++C G+E VC+ A +CF V ++ ++ +++ +LD +R+ F G+
Sbjct: 682 NIQKKNCHMEGKETVCINATVCFDVKLKSKEDTIYEADLQYRVTLDSLRQISRSFFSGTQ 741
Query: 720 QRLSPRRLRLSVGNVTCEQLHFHVLDTSDYLRPVALTVTFALDNTTKP--GPVLNEGSPT 777
+R R ++V C + F++LD D+ V +T+ F N T P GPVL++ P
Sbjct: 742 ERKVQR--NITVRKSECTKHSFYMLDKHDFQDSVRITLDF---NLTDPENGPVLDDSLPN 796
Query: 778 SIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKAPFVVRGGRRKVLVSTTLENRKENA 837
S+ + +PF+KDCG +C++DL L V + K +VR K VS T++N K++A
Sbjct: 797 SVHEYIPFAKDCGNKEKCISDLSLHV----ATTEKDLLIVRSQNDKFNVSLTVKNTKDSA 852
Query: 838 YNTSLSLIFSRNLHLASLTPQRESPIKVECAAPSAHARLCSVGHPVFQTGAKVTFLLEFE 897
YNT + +S NL + + E+ K C S H C VG+P + G VTF + F+
Sbjct: 853 YNTRTIVHYSPNLVFSGI----EAIQKDSC--ESNHNITCKVGYPFLRRGEMVTFKILFQ 906
Query: 898 FSCSSLLSQVFVKLTASSDSLERNGTLQDNTAQTSAYIQYEPHLLFSSESTLHRYEVHPY 957
F+ S L+ V + L+A+SDS E TL DN S ++YE L F S ++ + +
Sbjct: 907 FNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAAN 966
Query: 958 GTLP------VGPGPEFKTTLRVQNLGCYVVSGLIISALLPAVAHGGN---YFLSLSQVI 1008
T+P G E ++ G + + L +S P + G Y LS
Sbjct: 967 ETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSS-- 1024
Query: 1009 TNNASCIVQNLTEP------PGPPVHPEELQHTNRLNGSNTQCQVVRCHLGQLAKGTEVS 1062
+ NA+C +P + L+ L+ + + + C+L + ++V+
Sbjct: 1025 SENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTILDCNTCKFATITCNLTS-SDISQVN 1083
Query: 1063 VGLLRLVHNEFFRRAKFKSLTVVSTFELGTEEGSVLQLTEASRWSESLLEVVQT-RPILI 1121
V L ++ F ++ F SL + EL +E S L L+ +++ E +++ + P +
Sbjct: 1084 VSL--ILWKPTFIKSYFSSLNLTIRGELRSENAS-LVLSSSNQKRELAIQISKDGLPGRV 1140
Query: 1122 SLWILIGSVLGGLLLLALLVFCLWKLGFFAHKKIPEEEKREE 1163
LW+++ S GLLLL LL+ LWK+GFF K P ++K E+
Sbjct: 1141 PLWVILLSAFAGLLLLMLLILALWKIGFF---KRPLKKKMEK 1179
>gi|116295258 integrin alpha 2 precursor [Homo sapiens]
Length = 1181
Score = 659 bits (1699), Expect = 0.0
Identities = 407/1179 (34%), Positives = 633/1179 (53%), Gaps = 63/1179 (5%)
Query: 11 LPLVFLTGL-------CSPFNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGAPWD 63
LPL+ + L C +N+ ++F GP +FGY+V Q + W+LVG+PW
Sbjct: 11 LPLLLVLALSQGILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGNWLLVGSPWS 70
Query: 64 GPSGDRRGDVYRCPVGGAHNAPCAKGHLG-DYQLGNSSHPAVNMHLGMSLLETDGDGGFM 122
G +R GDVY+CPV A C K +L + N + NM LG+ L G GGF+
Sbjct: 71 GFPENRMGDVYKCPVD-LSTATCEKLNLQTSTSIPNVTEMKTNMSLGLILTRNMGTGGFL 129
Query: 123 ACAPLWSRACGSSVFSSGICARVDASFQPQGSLAPTAQRCPTYMDVVIVLDGSNSIYPWS 182
C PLW++ CG+ +++G+C+ + FQ S +P Q CP+ +DVV+V D SNSIYPW
Sbjct: 130 TCGPLWAQQCGNQYYTTGVCSDISPDFQLSASFSPATQPCPSLIDVVVVCDESNSIYPWD 189
Query: 183 EVQTFLRRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREGRE 242
V+ FL + V L I P + QVGL+QY +P ++L ++TKEE++ A S+ G
Sbjct: 190 AVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDL 249
Query: 243 TKTAQAIMVACTEGFSQSHGGRPEAARLLVVVTDGESHDGEELPAALKACEAGRVTRYGI 302
T T AI A +S + GGR A +++VVVTDGESHDG L A + C + R+GI
Sbjct: 250 TNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFGI 309
Query: 303 AVLGHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGSHA 362
AVLG+ R D + ++EI+ IAS P ER+FFNV+DEAAL + LG++IF +EG+
Sbjct: 310 AVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIFSIEGT-V 368
Query: 363 ENESSFGLEMSQIGFST--HRLKDGILFGMVGAYDWGGSVLW-LEGGHRLFPPRMALEDE 419
+ +F +EMSQ+GFS D ++ G VGA+ W G+++ GH +FP +
Sbjct: 369 QGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFP-----KQA 423
Query: 420 FPPALQ--NHAAYLGYSVSSMLLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSL 477
F LQ NH++YLGYSV++ + G F++GAPR + G+++ + + ++G + V Q+
Sbjct: 424 FDQILQDRNHSSYLGYSVAA-ISTGESTHFVAGAPRANYTGQIVLYSVNENGNITVIQAH 482
Query: 478 QGEQIGSYFGSELCPLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQG 537
+G+QIGSYFGS LC +D D+D TDVLLV APM++ KE GRVY++ + + L Q
Sbjct: 483 RGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKEGILGQHQF 542
Query: 538 TLQPEPPQDARFGFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQ 597
PE ++ RFG A+ AL D+N DGF DV VG+PLE+ + GA+Y+Y+G Q +R +Q
Sbjct: 543 LEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHQGTIRTKYSQ 602
Query: 598 RIAAA--SMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVT 655
+I + + L YFGRS+DG DL+GD + DV++GA G + L S+ I + T
Sbjct: 603 KILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIADVAIEASFT 662
Query: 656 PQAISVVQRDCRRRGQEAVCLTAALCFQVTSRTPGRWDHQFYMRFTASLD----EWTAGA 711
P+ I++V ++ + + LCF R P + ++Q + + +LD +
Sbjct: 663 PEKITLVNKNAQ--------IILKLCFSAKFR-PTKQNNQVAIVYNITLDADGFSSRVTS 713
Query: 712 RAAFDGSGQRLSPRRLRLSVGNVTCEQLHFHVLDTSDYLRPVALTVTFALDNTTKPG--P 769
R F + +R + + ++ +C + ++ + SD + + L V +L+N PG P
Sbjct: 714 RGLFKENNERCLQKNMVVNQAQ-SCPEHIIYIQEPSDVVNSLDLRVDISLEN---PGTSP 769
Query: 770 VLNEGSPTSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKAPFVVRGGRRKVLVSTT 829
L S T+ +PF KDCG D C++DLVL V I +++ PF+V +++ S T
Sbjct: 770 ALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVR-QIPAAQEQPFIVSNQNKRLTFSVT 828
Query: 830 LENRKENAYNTSLSLIFSRNLHLASLT-PQRESPIKVECAAPSAHARLCSVGHPVFQTGA 888
L+N++E+AYNT + + FS NL AS + P + + + AA S + C VG+P +
Sbjct: 829 LKNKRESAYNTGIVVDFSENLFFASFSLPVDGTEVTCQVAA-SQKSVACDVGYPALKREQ 887
Query: 889 KVTFLLEFEFSCSSLLSQVFVKLTASSDSLERNGTLQDNTAQTSAYIQYEPHLLFSSEST 948
+VTF + F+F+ +L +Q + A S+S E N DN + Y+ + + +
Sbjct: 888 QVTFTINFDFNLQNLQNQASLSFQALSESQEENKA--DNLVNLKIPLLYDAEIHLTRSTN 945
Query: 949 LHRYEVHPYGTLP------VGPGPEFKTTLRVQNLGCYVVSGLIISALLPAVAHGGNYFL 1002
++ YE+ G +P GP+F +L+V G VS + +P N +
Sbjct: 946 INFYEISSDGNVPSIVHSFEDVGPKFIFSLKV-TTGSVPVSMATVIIHIPQYTKEKNPLM 1004
Query: 1003 SLSQVITNNASCIVQNLTEPP--------GPPVHPEELQHTNRLNGSNTQCQVVRCHLGQ 1054
L+ V T+ A I N P E +HT LN C V C L
Sbjct: 1005 YLTGVQTDKAGDISCNADINPLKIGQTSSSVSFKSENFRHTKELNCRTASCSNVTCWLKD 1064
Query: 1055 LAKGTEVSVGLLRLVHNEFFRRAKFKSLTVVSTFELGTEEGSVLQLTEASRWSESLLEVV 1114
+ E V + + N F + F+++ + + E+ T + + E + + L+ +
Sbjct: 1065 VHMKGEYFVNVTTRIWNGTFASSTFQTVQLTAAAEINTYNPEI-YVIEDNTVTIPLMIMK 1123
Query: 1115 QTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFFAHK 1153
+ ++IGS++ G+LLL LV LWKLGFF K
Sbjct: 1124 PDEKAEVPTGVIIGSIIAGILLLLALVAILWKLGFFKRK 1162
>gi|62548866 integrin, alpha D precursor [Homo sapiens]
Length = 1161
Score = 403 bits (1035), Expect = e-112
Identities = 347/1181 (29%), Positives = 560/1181 (47%), Gaps = 96/1181 (8%)
Query: 23 FNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGAPWDGPSGDRRGDVYRCPVGGAH 82
FNLD P +F FG SV+Q GG R ++VGAP + + ++ G +Y C
Sbjct: 18 FNLDVEEPTIFQ-EDAGGFGQSVVQF--GGSR-LVVGAPLEVVAANQTGRLYDCAAATGM 73
Query: 83 NAPCAKGHLGDYQLGNSSHPAVNMHLGMSLLETDGDGGFMACAPLWSRACGSSVFSSGIC 142
P + AVNM LG++L + +AC P R CG + +S G C
Sbjct: 74 CQPIPL---------HIRPEAVNMSLGLTLAASTNGSRLLACGPTLHRVCGENSYSKGSC 124
Query: 143 ARVDASFQPQGSLAPTAQRCPTY-MDVVIVLDGSNSI--YPWSEVQTFLRRLVGKLFIDP 199
+ + ++ ++ CP MD+V ++DGS SI +++++ F++ ++G+ +
Sbjct: 125 LLLGSRWEIIQTVPDATPECPHQEMDIVFLIDGSGSIDQNDFNQMKGFVQAVMGQF--EG 182
Query: 200 EQIQVGLVQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREGRETKTAQAIMVACTEGFSQ 259
L+QY ++ FRT + + +G T TA I+ T+ F
Sbjct: 183 TDTLFALMQYSNLLKIHFTFTQFRTSPSQQSLVDPIVQLKGL-TFTATGILTVVTQLFHH 241
Query: 260 SHGGRPEAARLLVVVTDGESH-DGEELPAALKACEAGRVTRYGIAVLGHYLRRQRDPSSF 318
+G R A ++L+V+TDG+ + D E + E + RY I V GH + P++
Sbjct: 242 KNGARKSAKKILIVITDGQKYKDPLEYSDVIPQAEKAGIIRYAIGV-GHAFQ---GPTA- 296
Query: 319 LREIRTIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGSHAENESSFGLEMSQIGFS 378
+E+ TI+S P + F V + AAL I L ++I+ +EG+ + SSF EMSQ GFS
Sbjct: 297 RQELNTISSAPPQDHVFKVDNFAALGSIQKQLQEKIYAVEGTQSRASSSFQHEMSQEGFS 356
Query: 379 THRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMA--LEDEFPPALQNHAAYLGYSVS 436
T DG+ G VG++ W GG L+PP M+ + + +YLGYS
Sbjct: 357 TALTMDGLFLGAVGSFSW-------SGGAFLYPPNMSPTFINMSQENVDMRDSYLGYSTE 409
Query: 437 SMLLRGGRRLFLSGAPRFRHRGKVIAF-QLKKDGAVRVAQSLQGEQIGSYFGSELCPLDT 495
L +G + L L GAPR++H GK + F Q+ + R + G QIGSYFG+ LC +D
Sbjct: 410 LALWKGVQNLVL-GAPRYQHTGKAVIFTQVSRQW--RKKAEVTGTQIGSYFGASLCSVDV 466
Query: 496 DRDGTTDVLLVAAPMFLGPQNKETGRVYVY-----LVGQQSLLTLQGTLQPEPPQDARFG 550
D DG+TD++L+ AP + + G+V V V Q L+G Q P RFG
Sbjct: 467 DSDGSTDLILIGAPHYY--EQTRGGQVSVCPLPRGRVQWQCDAVLRGE-QGHP--WGRFG 521
Query: 551 FAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHG-TQSGVRPHPAQRIAAASMPHALS 609
A+ L D+N+D DVA+GAP E ++GA+YL+HG ++SG+ P +QRIA++ + L
Sbjct: 522 AALTVLGDVNEDKLIDVAIGAPGEQENRGAVYLFHGASESGISPSHSQRIASSQLSPRLQ 581
Query: 610 YFGRSVDGRLDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAISVVQRDC--- 666
YFG+++ G DL D L+D+AVGA+G +LL S P++ + ++ +P ++ C
Sbjct: 582 YFGQALSGGQDLTQDGLMDLAVGARGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRCWEE 641
Query: 667 ----RRRGQEAVCLTAALCFQVTSRTPGRWDHQFYMRFTASLDEWTAGARAAFDGSGQRL 722
G VCLT S D Q +RF +LD +RA F+ +
Sbjct: 642 KPSALEAGDATVCLTIQ-----KSSLDQLGDIQSSVRFDLALDPGRLTSRAIFNETKNPT 696
Query: 723 SPRRLRLSVGNVTCEQLHFHVLD-TSDYLRPVALTVTFALDNTTKPG-----PVLNEGSP 776
RR L +G + CE L + D D + P+ L + F+L P PVL GS
Sbjct: 697 LTRRKTLGLG-IHCETLKLLLPDCVEDVVSPIILHLNFSLVREPIPSPQNLRPVLAVGSQ 755
Query: 777 TSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKAPFVVRGGRRKVLVSTTLENRKEN 836
+PF K+CG D C D L V + G + + G ++ V T+ N E+
Sbjct: 756 DLFTASLPFEKNCGQDGLCEGD--LGVTLSFSGLQT---LTVGSSLELNVIVTVWNAGED 810
Query: 837 AYNTSLSLIFSRNLHLASLTPQRESP----IKVEC-AAPSAHARL----CSVGHPVFQTG 887
+Y T +SL + L ++ ++ P +++ C P+ L CSV HP+F G
Sbjct: 811 SYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRSSRCSVNHPIFHEG 870
Query: 888 AKVTFLLEFEFSCSSLLSQVFVKLTASSDSLERNGTLQDNTAQTSAYIQYEPHLLFSSES 947
+ TF++ F+ S + L + + AS+ S + T Q ++Y + + S +
Sbjct: 871 SNGTFIVTFDVSYKATLGDRML-MRASASSENNKASSSKATFQLELPVKYAVYTMISRQE 929
Query: 948 TLHRYEVHPYGTLPVGPGPEFKTTLRVQNLGCYVVSGLIISALLPAVAHGGNYFLSLSQV 1007
+Y + T E + RV NL ++ + I+ +P + +G + + +
Sbjct: 930 ESTKY--FNFATSDEKKMKEAEHRYRVNNLSQRDLA-ISINFWVPVLLNGVAVWDVVMEA 986
Query: 1008 ITNNASCIVQNLTEPPGPPVHPEELQHTNR---LNGSNTQCQVVRCHLGQLAKGTEVSVG 1064
+ + C+ + PP H + L +R L+ S C RC + + E+
Sbjct: 987 PSQSLPCVSER-----KPPQHSDFLTQISRSPMLDCSIADCLQFRCDVPSFSVQEELDFT 1041
Query: 1065 LLRLVHNEFFRRAKFKSLTVVSTFELGTEEGSVLQLTEASRWSESLLE-VVQTRPILISL 1123
L + + R K + VVS E+ + QL + + +E V++ + ++
Sbjct: 1042 LKGNLSFGWVRETLQKKVLVVSVAEITFDTSVYSQLPGQEAFMRAQMEMVLEEDEVYNAI 1101
Query: 1124 WILIGSVLGGLLLLALLVFCLWKLGFF-AHKKIPEEEKREE 1163
I++GS +G LLLLAL+ L+KLGFF H K E+K E+
Sbjct: 1102 PIIMGSSVGALLLLALITATLYKLGFFKRHYKEMLEDKPED 1142
>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
Length = 1153
Score = 384 bits (987), Expect = e-106
Identities = 346/1174 (29%), Positives = 553/1174 (47%), Gaps = 94/1174 (8%)
Query: 19 LCSPFNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGAPWDGPSGDRRGDVYRCPV 78
LC FNLD + F FG SV+Q G ++VGAP + + ++RG +Y+C
Sbjct: 13 LCHGFNLDTENAMTFQENARG-FGQSVVQLQGSR---VVVGAPQEIVAANQRGSLYQC-- 66
Query: 79 GGAHNAPCAKGHLGDYQLGNSSH-------PAVNMHLGMSLLETDGDGGFMACAPLWSRA 131
DY G+ AVNM LG+SL T +AC P +
Sbjct: 67 --------------DYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQT 112
Query: 132 CGSSVFSSGICARVDASFQPQGSLAPTAQR-CPTY-MDVVIVLDGSNSIYP--WSEVQTF 187
C + + G+C ++ + Q P A R CP D+ ++DGS SI P + ++ F
Sbjct: 113 CSENTYVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEF 172
Query: 188 LRRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREGRETKTAQ 247
+ ++ +L + L+QY E ++ +F+ K +++ GR T TA
Sbjct: 173 VSTVMEQL--KKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGR-THTAT 229
Query: 248 AIMVACTEGFSQSHGGRPEAARLLVVVTDGESHDGEELPAALKACEAGR--VTRYGIAVL 305
I E F+ ++G R A ++LVV+TDGE G+ L EA R V RY I V
Sbjct: 230 GIRKVVRELFNITNGARKNAFKILVVITDGEKF-GDPLGYEDVIPEADREGVIRYVIGV- 287
Query: 306 GHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGSHAENE 365
G R ++ +E+ TIAS P F V + AL I + L ++IF +EG+ +
Sbjct: 288 GDAFRSEKSR----QELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSS 343
Query: 366 SSFGLEMSQIGFSTHRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEFPPALQ 425
SSF EMSQ GFS +G L VG+YDW G V + M D
Sbjct: 344 SSFEHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDS-----D 398
Query: 426 NHAAYLGYSVSSMLLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSLQGEQIGSY 485
+ AYLGY+ ++++LR + + GAPR++H G V F+ + G +++G QIG+Y
Sbjct: 399 MNDAYLGYA-AAIILRNRVQSLVLGAPRYQHIGLVAMFR-QNTGMWESNANVKGTQIGAY 456
Query: 486 FGSELCPLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLV--GQQSLLTLQGTLQPEP 543
FG+ LC +D D +G+TD++L+ AP + + G+V V + GQ++ L E
Sbjct: 457 FGASLCSVDVDSNGSTDLVLIGAPHYY--EQTRGGQVSVCPLPRGQRARWQCDAVLYGEQ 514
Query: 544 PQD-ARFGFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQ-SGVRPHPAQRIAA 601
Q RFG A+ L D+N D DVA+GAP E+ ++GA+YL+HGT SG+ P +QRIA
Sbjct: 515 GQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAG 574
Query: 602 ASMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAISV 661
+ + L YFG+S+ G DL D LVD+ VGAQG +LL S+P++ + +E P+ ++
Sbjct: 575 SKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVAR 634
Query: 662 VQRDCRR---RGQEAVCLTAALCFQVTSRTPGRWDH-QFYMRFTASLDEWTAGARAAFDG 717
+C +G+EA + L Q ++R R Q + + +LD +RA F+
Sbjct: 635 NVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSGRPHSRAVFNE 694
Query: 718 SGQRLSPRRLRLSVG-NVTCEQLHFHVLDT-SDYLRPVALTVTFALDNTTKPG-----PV 770
+ + S RR +G TCE L + + D + P+ L + F+L T PV
Sbjct: 695 T--KNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPV 752
Query: 771 LNEGSPTSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKAPFVVRGGRRKVLVSTTL 830
L E + L PF K+CG DN C DL + + +V GG R+ V+ T+
Sbjct: 753 LAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSF-----MSLDCLVVGGPREFNVTVTV 807
Query: 831 ENRKENAYNTSLSLIFSRNLH---LASLTPQR-ESPIKVECAAPSA-------HARLCSV 879
N E++Y T ++ F +L +++L QR + ++ C + S+ + CS+
Sbjct: 808 RNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSI 867
Query: 880 GHPVFQTGAKVTFLLEFEF-SCSSLLSQVFVKLTASSDSLERNGTLQDNTA-QTSAYIQY 937
HP+F ++VTF + F+ S +SL +++ +K +S E N + T Q ++Y
Sbjct: 868 NHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTS---ENNMPRTNKTEFQLELPVKY 924
Query: 938 EPHLLFSSESTLHRYEVHPYGTLPVGPGPEFKTTLRVQNLGCYVVSGLIISALLPAVAHG 997
+++ +S +Y T + +V NLG + + + L+P +
Sbjct: 925 AVYMVVTSHGVSTKYLNF---TASENTSRVMQHQYQVSNLGQRSLP-ISLVFLVPVRLNQ 980
Query: 998 GNYFLSLSQVITNNASCIVQNLTEPPGPPVHPEELQHTNRLNGSNTQCQVVRCHLGQLAK 1057
+ + N S P EL+ +N S CQ ++C +
Sbjct: 981 TVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGI 1040
Query: 1058 GTEVSVGLLRLVHNEFFRRAKFKSLTVVSTFELGTEEGSVLQLTEASRWSESLLEV-VQT 1116
E + L + +++ + L +VST E+ + L + S E V+
Sbjct: 1041 QEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLPGQGAFVRSQTETKVEP 1100
Query: 1117 RPILISLWILIGSVLGGLLLLALLVFCLWKLGFF 1150
+ L +++GS +GGLLLLAL+ L+KLGFF
Sbjct: 1101 FEVPNPLPLIVGSSVGGLLLLALITAALYKLGFF 1134
>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
Length = 1152
Score = 380 bits (977), Expect = e-105
Identities = 345/1173 (29%), Positives = 551/1173 (46%), Gaps = 93/1173 (7%)
Query: 19 LCSPFNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGAPWDGPSGDRRGDVYRCPV 78
LC FNLD + F FG SV+Q G ++VGAP + + ++RG +Y+C
Sbjct: 13 LCHGFNLDTENAMTFQENARG-FGQSVVQLQGSR---VVVGAPQEIVAANQRGSLYQC-- 66
Query: 79 GGAHNAPCAKGHLGDYQLGNSSH-------PAVNMHLGMSLLETDGDGGFMACAPLWSRA 131
DY G+ AVNM LG+SL T +AC P +
Sbjct: 67 --------------DYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQT 112
Query: 132 CGSSVFSSGICARVDASFQPQGSLAPTAQR-CPTY-MDVVIVLDGSNSIYP--WSEVQTF 187
C + + G+C ++ + Q P A R CP D+ ++DGS SI P + ++ F
Sbjct: 113 CSENTYVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEF 172
Query: 188 LRRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREGRETKTAQ 247
+ ++ +L + L+QY E ++ +F+ K +++ GR T TA
Sbjct: 173 VSTVMEQL--KKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGR-THTAT 229
Query: 248 AIMVACTEGFSQSHGGRPEAARLLVVVTDGESHDGEELPAALKACEAGR--VTRYGIAVL 305
I E F+ ++G R A ++LVV+TDGE G+ L EA R V RY I V
Sbjct: 230 GIRKVVRELFNITNGARKNAFKILVVITDGEKF-GDPLGYEDVIPEADREGVIRYVIGV- 287
Query: 306 GHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGSHAENE 365
G R ++ +E+ TIAS P F V + AL I + L ++IF +EG+ +
Sbjct: 288 GDAFRSEKSR----QELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSS 343
Query: 366 SSFGLEMSQIGFSTHRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEFPPALQ 425
SSF EMSQ GFS +G L VG+YDW G V + M D
Sbjct: 344 SSFEHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDS-----D 398
Query: 426 NHAAYLGYSVSSMLLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSLQGEQIGSY 485
+ AYLGY+ ++++LR + + GAPR++H G V F+ + G +++G QIG+Y
Sbjct: 399 MNDAYLGYA-AAIILRNRVQSLVLGAPRYQHIGLVAMFR-QNTGMWESNANVKGTQIGAY 456
Query: 486 FGSELCPLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVY-LVGQQSLLTLQGTLQPEPP 544
FG+ LC +D D +G+TD++L+ AP + + G+V V L ++ L E
Sbjct: 457 FGASLCSVDVDSNGSTDLVLIGAPHYY--EQTRGGQVSVCPLPRGRARWQCDAVLYGEQG 514
Query: 545 QD-ARFGFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQ-SGVRPHPAQRIAAA 602
Q RFG A+ L D+N D DVA+GAP E+ ++GA+YL+HGT SG+ P +QRIA +
Sbjct: 515 QPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGS 574
Query: 603 SMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAISVV 662
+ L YFG+S+ G DL D LVD+ VGAQG +LL S+P++ + +E P+ ++
Sbjct: 575 KLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARN 634
Query: 663 QRDCRR---RGQEAVCLTAALCFQVTSRTPGRWDH-QFYMRFTASLDEWTAGARAAFDGS 718
+C +G+EA + L Q ++R R Q + + +LD +RA F+ +
Sbjct: 635 VFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSGRPHSRAVFNET 694
Query: 719 GQRLSPRRLRLSVG-NVTCEQLHFHVLDT-SDYLRPVALTVTFALDNTTKPG-----PVL 771
+ S RR +G TCE L + + D + P+ L + F+L T PVL
Sbjct: 695 --KNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVL 752
Query: 772 NEGSPTSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKAPFVVRGGRRKVLVSTTLE 831
E + L PF K+CG DN C DL + + +V GG R+ V+ T+
Sbjct: 753 AEDAQRLFTALFPFEKNCGNDNICQDDLSITFSF-----MSLDCLVVGGPREFNVTVTVR 807
Query: 832 NRKENAYNTSLSLIFSRNLH---LASLTPQR-ESPIKVECAAPSA-------HARLCSVG 880
N E++Y T ++ F +L +++L QR + ++ C + S+ + CS+
Sbjct: 808 NDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSIN 867
Query: 881 HPVFQTGAKVTFLLEFEF-SCSSLLSQVFVKLTASSDSLERNGTLQDNTA-QTSAYIQYE 938
HP+F ++VTF + F+ S +SL +++ +K +S E N + T Q ++Y
Sbjct: 868 HPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTS---ENNMPRTNKTEFQLELPVKYA 924
Query: 939 PHLLFSSESTLHRYEVHPYGTLPVGPGPEFKTTLRVQNLGCYVVSGLIISALLPAVAHGG 998
+++ +S +Y T + +V NLG + + + L+P +
Sbjct: 925 VYMVVTSHGVSTKYLNF---TASENTSRVMQHQYQVSNLGQRSLP-ISLVFLVPVRLNQT 980
Query: 999 NYFLSLSQVITNNASCIVQNLTEPPGPPVHPEELQHTNRLNGSNTQCQVVRCHLGQLAKG 1058
+ + N S P EL+ +N S CQ ++C +
Sbjct: 981 VIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQ 1040
Query: 1059 TEVSVGLLRLVHNEFFRRAKFKSLTVVSTFELGTEEGSVLQLTEASRWSESLLEV-VQTR 1117
E + L + +++ + L +VST E+ + L + S E V+
Sbjct: 1041 EEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLPGQGAFVRSQTETKVEPF 1100
Query: 1118 PILISLWILIGSVLGGLLLLALLVFCLWKLGFF 1150
+ L +++GS +GGLLLLAL+ L+KLGFF
Sbjct: 1101 EVPNPLPLIVGSSVGGLLLLALITAALYKLGFF 1133
>gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]
Length = 1170
Score = 380 bits (975), Expect = e-105
Identities = 348/1185 (29%), Positives = 543/1185 (45%), Gaps = 134/1185 (11%)
Query: 15 FLTGLCSPFNLDEHHPRLFPGPPEA--EFGYSVLQHVGGGQRWMLVGAPWDGPSGDRRGD 72
F S +NLD R F PP A FGY VLQ VG G ++VGAP +G S G
Sbjct: 18 FFFAPASSYNLDVRGARSF-SPPRAGRHFGYRVLQ-VGNG---VIVGAPGEGNS---TGS 69
Query: 73 VYRCPVGGAHNAPCAKGHLGDYQLGNSSHPAVNMHLGMSLLETDGDGGFMACAPLWSRAC 132
+Y+C G H P L S++ + +LGM+L DG +AC P SR C
Sbjct: 70 LYQCQSGTGHCLPVT--------LRGSNY--TSKYLGMTLATDPTDGSILACDPGLSRTC 119
Query: 133 GSSVFSSGICARVDASFQ-PQGSLAPTAQRC-PTYMDVVIVLDGSNSIYP--WSEVQTFL 188
+ + SG+C + Q P P Q C +D+V + DGS S+ P + ++ F+
Sbjct: 120 DQNTYLSGLCYLFRQNLQGPMLQGRPGFQECIKGNVDLVFLFDGSMSLQPDEFQKILDFM 179
Query: 189 RRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREGRETKTAQA 248
+ ++ KL Q VQ+ S E+ D+ +++ K++ T T A
Sbjct: 180 KDVMKKL--SNTSYQFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHML-LLTNTFGA 236
Query: 249 IMVACTEGFSQSHGGRPEAARLLVVVTDGESHDGEELPAALKACEAGRVTRYGIAVLGHY 308
I TE F + G RP+A ++L+++TDGE+ D + AA + RY I + H+
Sbjct: 237 INYVATEVFREELGARPDATKVLIIITDGEATDSGNIDAAKD------IIRYIIGIGKHF 290
Query: 309 LRRQRDPSSFLREIRTIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGSHAENESSF 368
++ + + AS P F + L D+ L +I+ +EG+ ++ +SF
Sbjct: 291 QTKESQET-----LHKFASKPASEFVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSF 345
Query: 369 GLEMSQIGFSTHRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEF----PPAL 424
+E+S G S + + G VGA DW G L L+ + +D F P
Sbjct: 346 NMELSSSGISADLSRGHAVVGAVGAKDWAGGFLDLKADLQ--------DDTFIGNEPLTP 397
Query: 425 QNHAAYLGYSVSSMLLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAV-RVAQSLQGEQIG 483
+ A YLGY+V+ + R L SGAPR++H G+V+ FQ + G Q++ G QIG
Sbjct: 398 EVRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIG 457
Query: 484 SYFGSELCPLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYL---VGQQSLLTLQGTLQ 540
SYFG ELC +D D+DG T++LL+ AP+F G Q GRV++Y +G + + LQG
Sbjct: 458 SYFGGELCGVDVDQDGETELLLIGAPLFYGEQRG--GRVFIYQRRQLGFEEVSELQG--D 513
Query: 541 PEPPQDARFGFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIA 600
P P RFG A+ AL D+N DG DVAVGAPLE+ QGA+Y+++G G+ P P+QRI
Sbjct: 514 PGYPL-GRFGEAITALTDINGDGLVDVAVGAPLEE--QGAVYIFNGRHGGLSPQPSQRIE 570
Query: 601 AASMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAIS 660
+ + +FGRS+ G DL+GD L DVAVGA+ I+LSSRP+V + + +P I
Sbjct: 571 GTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMSFSPAEIP 630
Query: 661 VVQRDC----RRRGQEAVCLTAALCFQVTSRTPGRWDHQFYMR------FTASLDEWTAG 710
V + +C + +E V +T +CFQ+ S P QF R +T LD
Sbjct: 631 VHEVECSYSTSNKMKEGVNIT--ICFQIKSLIP-----QFQGRLVANLTYTLQLDGHRTR 683
Query: 711 ARAAFDGSGQRLSPRRLRLSVGNVTCEQLHFHV-LDTSDYLRPVALTVTFAL---DNTTK 766
R F G L RR +++C FH + D + P+ +++ F+L + T +
Sbjct: 684 RRGLFPGGRHEL--RRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPR 741
Query: 767 PGPVLNEGSPTSIQKL-------VPFSKDCGPDNECVTDLVLQVN-MDIRGSRKAPFVVR 818
+ P ++ +PF K+CG D +C +L + + R R F
Sbjct: 742 DQRAQGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVSFSPARSRALRLTAFA-- 799
Query: 819 GGRRKVLVSTTLENRKENAYNTSLSLIFSRNLHLASLTPQR-ESPIKVECAAPSAHARL- 876
+ V +L N +E+AY L L F L + + S I V C +RL
Sbjct: 800 ----SLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLL 855
Query: 877 -----CSVGHPVFQTGAKVTFLLEFEFSCSSLLSQVFVKLTASSDSLERNGTLQDNTAQT 931
C+V P+F+ G V + F +S + + E + L+DN+A T
Sbjct: 856 SRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNEDSDLLEDNSATT 915
Query: 932 SAYIQYEPHLLFSSESTLHRYEVHPYGTLPVGPGPEFKTTLRVQNLGCYVVSGLIISALL 991
I Y ++L + TL V P+ +V+++ + I +
Sbjct: 916 IIPILYPINILIQDQED---------STLYVSFTPKGPKIHQVKHMYQVRIQPSIHDHNI 966
Query: 992 PAVAHGGNYFLSLSQVITNNASCIVQNLTEPPGPPVHPEELQHTNRLNGSNTQC---QVV 1048
P + + + Q + ++ P P H E+L+ RL + C +
Sbjct: 967 PTL----EAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLE---RLPDAAEPCLPGALF 1019
Query: 1049 RCHLGQLAKGTEVSVGLLRLVHNEFFRRAKFKSLTVVSTFELGTEEGSVLQLTEASRWSE 1108
RC + + +G L LV E + F ++ S+ + L + +
Sbjct: 1020 RCPVVFRQEILVQVIGTLELV-GEIEASSMF---SLCSSLSISFNSSKHFHLYGS---NA 1072
Query: 1109 SLLEVVQTRPILIS---LWILIGSVLGGLLLLALLVFCLWKLGFF 1150
SL +VV ++ L++ + S +GGLLLL L+ L+K+GFF
Sbjct: 1073 SLAQVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFF 1117
>gi|34452173 integrin alpha X precursor [Homo sapiens]
Length = 1163
Score = 358 bits (920), Expect = 1e-98
Identities = 340/1202 (28%), Positives = 552/1202 (45%), Gaps = 122/1202 (10%)
Query: 13 LVFLTGLCSP--FNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGAPWDGPSGDRR 70
L+ T L + FNLD F A FG SV+Q+ W++VGAP + ++
Sbjct: 8 LLLFTALATSLGFNLDTEELTAFR-VDSAGFGDSVVQYANS---WVVVGAPQKITAANQT 63
Query: 71 GDVYRCPVGGAHNAPCAKGHLGDYQLGNSSHP-AVNMHLGMSLLETDGDGGFMACAPLWS 129
G +Y+C G C +G P AVNM LG+SL T +AC P
Sbjct: 64 GGLYQC---GYSTGACEP-------IGLQVPPEAVNMSLGLSLASTTSPSQLLACGPTVH 113
Query: 130 RACGSSVFSSGICARVDASFQPQGSLAPTAQRCPTY-MDVVIVLDGSNSIYP--WSEVQT 186
CG +++ +G+C + + Q L + Q CP D+V ++DGS SI ++ +
Sbjct: 114 HECGRNMYLTGLCFLLGPTQLTQ-RLPVSRQECPRQEQDIVFLIDGSGSISSRNFATMMN 172
Query: 187 FLRRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREGRETKTA 246
F+R ++ + Q L+Q+ ++ +FR + ++ + +G T TA
Sbjct: 173 FVRAVISQF--QRPSTQFSLMQFSNKFQTHFTFEEFRRSSNPLSLLASVHQLQGF-TYTA 229
Query: 247 QAIMVACTEGFSQSHGGRPEAARLLVVVTDGESH-DGEELPAALKACEAGRVTRYGIAVL 305
AI F S+G R +AA++L+V+TDG+ D + + +A + RY I V
Sbjct: 230 TAIQNVVHRLFHASYGARRDAAKILIVITDGKKEGDSLDYKDVIPMADAAGIIRYAIGVG 289
Query: 306 GHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGSHAENE 365
+ R +E+ IAS P + F V D AL DI + L ++IF +EG+ +
Sbjct: 290 LAFQNRNS-----WKELNDIASKPSQEHIFKVEDFDALKDIQNQLKEKIFAIEGTETTSS 344
Query: 366 SSFGLEMSQIGFSTHRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEFPPALQ 425
SSF LEM+Q GFS DG + G VG++ W G G L+PP M+ F Q
Sbjct: 345 SSFELEMAQEGFSAVFTPDGPVLGAVGSFTWSG-------GAFLYPPNMS--PTFINMSQ 395
Query: 426 NHA----AYLGYSVSSMLLRGGRRLFLSGAPRFRHRGKVIAF-QLKKDGAVRVAQSLQGE 480
+ +YLGYS L +G + L L GAPR++H GK + F Q+ + R+ + G
Sbjct: 396 ENVDMRDSYLGYSTELALWKGVQSLVL-GAPRYQHTGKAVIFTQVSRQW--RMKAEVTGT 452
Query: 481 QIGSYFGSELCPLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVY-LVGQQSLLTLQGTL 539
QIGSYFG+ LC +D D DG+TD++L+ AP + + G+V V L L
Sbjct: 453 QIGSYFGASLCSVDVDSDGSTDLVLIGAPHYY--EQTRGGQVSVCPLPRGWRRWWCDAVL 510
Query: 540 QPEPPQD-ARFGFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQS-GVRPHPAQ 597
E RFG A+ L D+N D DV +GAP E+ ++GA+YL+HG + P +Q
Sbjct: 511 YGEQGHPWGRFGAALTVLGDVNGDKLTDVVIGAPGEEENRGAVYLFHGVLGPSISPSHSQ 570
Query: 598 RIAAASMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQ 657
RIA + + L YFG+++ G DL D LVD+AVGA+G +LL +RP++ + S++ P
Sbjct: 571 RIAGSQLSSRLQYFGQALSGGQDLTQDGLVDLAVGARGQVLLLRTRPVLWVGVSMQFIPA 630
Query: 658 AISVVQRDCRRRG-QEAVCLTAALCFQVTSRTP---GRWDHQFYMRFTASLDEWTAGARA 713
I +CR + E + + +C + R+ G D Q + +LD RA
Sbjct: 631 EIPRSAFECREQVVSEQTLVQSNICLYIDKRSKNLLGSRDLQSSVTLDLALDPGRLSPRA 690
Query: 714 AFDGSGQRLSPRRLRLSVGNVTCEQLHFHVLDTS---DYLRPVALTVTFALDNTTKP--- 767
F + R S R+R+ CE +F++L S D + P+ L + F L KP
Sbjct: 691 TFQETKNR-SLSRVRVLGLKAHCE--NFNLLLPSCVEDSVTPITLRLNFTL--VGKPLLA 745
Query: 768 ----GPVLNEGSPTSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKAPFVVRGGRRK 823
P+L + +PF K+CG D+ C +L + + G +
Sbjct: 746 FRNLRPMLAADAQRYFTASLPFEKNCGADHICQDNLGISFSFP-------------GLKS 792
Query: 824 VLVSTTLE--------NRKENAYNTSLSLIFSRNLHLASLTP-QRESPIK---VEC-AAP 870
+LV + LE N E++Y T+++ L + Q++ ++ + C +AP
Sbjct: 793 LLVGSNLELNAEVMVWNDGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAP 852
Query: 871 ----SAHARLCSVGHPVFQTGAKVTFLLEFEFSCSSLLSQVFVKLTASSDSLERNGTLQD 926
+ C + H +F+ GA++TFL F+ S ++L + LTA+ S
Sbjct: 853 VGSQGTWSTSCRINHLIFRGGAQITFLATFDVSPKAVLGDRLL-LTANVSSENNTPRTSK 911
Query: 927 NTAQTSAYIQYEPHLLFSSESTLHRYEVHPYGTLPVGPGPEFKTTL-----RVQNLGCYV 981
T Q ++Y + + SS +Y L E ++ + +V NLG
Sbjct: 912 TTFQLELPVKYAVYTVVSSHEQFTKY-------LNFSESEEKESHVAMHRYQVNNLGQRD 964
Query: 982 VSGLIISALLPAVAHGGNYFLSLSQVITNNASCIVQNLTEPPGPPVHP--EELQHTNRLN 1039
+ + I+ +P + ++ + N S ++ +E PP +Q L+
Sbjct: 965 LP-VSINFWVPVELNQEAVWMDVEVSHPQNPS--LRCSSEKIAPPASDFLAHIQKNPVLD 1021
Query: 1040 GSNTQCQVVRCHLGQLAKGTEVSVGLLRLVHNEFFRRAKFKSLTVVSTFELGTEEGSVLQ 1099
S C RC + + E+ L + + R+ K ++VVS E+ + Q
Sbjct: 1022 CSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKKVSVVSVAEITFDTSVYSQ 1081
Query: 1100 LTEASRWSES-LLEVVQTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFF--AHKKIP 1156
L + + V++ + +++GS +GGLLLLAL+ L+K+GFF +K++
Sbjct: 1082 LPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLALITAVLYKVGFFKRQYKEMM 1141
Query: 1157 EE 1158
EE
Sbjct: 1142 EE 1143
>gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]
Length = 1086
Score = 316 bits (810), Expect = 7e-86
Identities = 286/986 (29%), Positives = 450/986 (45%), Gaps = 107/986 (10%)
Query: 207 VQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREGRETKTAQAIMVACTEGFSQSHGGRPE 266
VQ+ S E+ D+ +++ K++ T T AI TE F + G RP+
Sbjct: 113 VQFSTSYKTEFDFSDYVKRKDPDALLKHVKHML-LLTNTFGAINYVATEVFREELGARPD 171
Query: 267 AARLLVVVTDGESHDGEELPAALKACEAGRVTRYGIAVLGHYLRRQRDPSSFLREIRTIA 326
A ++L+++TDGE+ D + AA + RY I + H+ ++ + + A
Sbjct: 172 ATKVLIIITDGEATDSGNIDAAKD------IIRYIIGIGKHFQTKESQET-----LHKFA 220
Query: 327 SDPDERFFFNVTDEAALTDIVDALGDRIFGLEGSHAENESSFGLEMSQIGFSTHRLKDGI 386
S P F + L D+ L +I+ +EG+ ++ +SF +E+S G S +
Sbjct: 221 SKPASEFVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHA 280
Query: 387 LFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEF----PPALQNHAAYLGYSVSSMLLRG 442
+ G VGA DW G L L+ + +D F P + A YLGY+V+ + R
Sbjct: 281 VVGAVGAKDWAGGFLDLKADLQ--------DDTFIGNEPLTPEVRAGYLGYTVTWLPSRQ 332
Query: 443 GRRLFLSGAPRFRHRGKVIAFQLKKDGAV-RVAQSLQGEQIGSYFGSELCPLDTDRDGTT 501
L SGAPR++H G+V+ FQ + G Q++ G QIGSYFG ELC +D D+DG T
Sbjct: 333 KTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGET 392
Query: 502 DVLLVAAPMFLGPQNKETGRVYVYL---VGQQSLLTLQGTLQPEPPQDARFGFAMGALPD 558
++LL+ AP+F G Q GRV++Y +G + + LQG P P RFG A+ AL D
Sbjct: 393 ELLLIGAPLFYGEQRG--GRVFIYQRRQLGFEEVSELQG--DPGYPL-GRFGEAITALTD 447
Query: 559 LNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAASMPHALSYFGRSVDGR 618
+N DG DVAVGAPLE+ QGA+Y+++G G+ P P+QRI + + +FGRS+ G
Sbjct: 448 INGDGLVDVAVGAPLEE--QGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGV 505
Query: 619 LDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAISVVQRDC----RRRGQEAV 674
DL+GD L DVAVGA+ I+LSSRP+V + + +P I V + +C + +E V
Sbjct: 506 KDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGV 565
Query: 675 CLTAALCFQVTSRTPGRWDHQFYMR------FTASLDEWTAGARAAFDGSGQRLSPRRLR 728
+T +CFQ+ S P QF R +T LD R F G L RR
Sbjct: 566 NIT--ICFQIKSLIP-----QFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHEL--RRNI 616
Query: 729 LSVGNVTCEQLHFHV-LDTSDYLRPVALTVTFAL---------DNTTKPGPVLNEGSPTS 778
+++C FH + D + P+ +++ F+L K P + S S
Sbjct: 617 AVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRAGKDIPPILRPSLHS 676
Query: 779 IQKLVPFSKDCGPDNECVTDLVLQVN-MDIRGSRKAPFVVRGGRRKVLVSTTLENRKENA 837
+PF K+CG D +C +L + + R R F + V +L N +E+A
Sbjct: 677 ETWEIPFEKNCGEDKKCEANLRVSFSPARSRALRLTAFA------SLSVELSLSNLEEDA 730
Query: 838 YNTSLSLIFSRNLHLASLTPQR-ESPIKVECAAPSAHARL------CSVGHPVFQTGAKV 890
Y L L F L + + S I V C +RL C+V P+F+ G V
Sbjct: 731 YWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSV 790
Query: 891 TFLLEFEFSCSSLLSQVFVKLTASSDSLERNGTLQDNTAQTSAYIQYEPHLLFSSESTLH 950
+ F +S + + E + L+DN+A T I Y ++L +
Sbjct: 791 ALQMMFNTLVNSSWGDSVELHANVTCNNEDSDLLEDNSATTIIPILYPINILIQDQED-- 848
Query: 951 RYEVHPYGTLPVGPGPEFKTTLRVQNLGCYVVSGLIISALLPAVAHGGNYFLSLSQVITN 1010
TL V P+ +V+++ + I +P + + + Q +
Sbjct: 849 -------STLYVSFTPKGPKIHQVKHMYQVRIQPSIHDHNIPTL----EAVVGVPQPPSE 897
Query: 1011 NASCIVQNLTEPPGPPVHPEELQHTNRLNGSNTQC---QVVRCHLGQLAKGTEVSVGLLR 1067
++ P P H E+L+ RL + C + RC + + +G L
Sbjct: 898 GPITHQWSVQMEPPVPCHYEDLE---RLPDAAEPCLPGALFRCPVVFRQEILVQVIGTLE 954
Query: 1068 LVHNEFFRRAKFKSLTVVSTFELGTEEGSVLQLTEASRWSESLLEVVQTRPILIS---LW 1124
LV E + F ++ S+ + L + + SL +VV ++ L+
Sbjct: 955 LV-GEIEASSMF---SLCSSLSISFNSSKHFHLYGS---NASLAQVVMKVDVVYEKQMLY 1007
Query: 1125 ILIGSVLGGLLLLALLVFCLWKLGFF 1150
+ + S +GGLLLL L+ L+K+GFF
Sbjct: 1008 LYVLSGIGGLLLLLLIFIVLYKVGFF 1033
>gi|148728188 integrin, alpha E precursor [Homo sapiens]
Length = 1179
Score = 310 bits (793), Expect = 7e-84
Identities = 249/761 (32%), Positives = 381/761 (50%), Gaps = 64/761 (8%)
Query: 167 DVVIVLDGSNSIYP--WSEVQTFLRRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGDFRT 224
++ I+LDGS SI P + + F+ ++ + + LVQYG E+ L D +
Sbjct: 202 EIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQD 261
Query: 225 KEEVVRAAKNLSRREGRETKTAQAIMVACTEGFSQSHGGRPEAARLLVVVTDGES-HDGE 283
+ +N+++ G TKTA A+ F+ SHG R +A++++VV+TDG D
Sbjct: 262 VMASLARVQNITQ-VGSVTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPL 320
Query: 284 ELPAALKACEAGRVTRYGIAVLGHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDEAAL 343
L + + + V R+ I V G + R RE+ IASDPDE F VT+ AL
Sbjct: 321 NLTTVINSPKMQGVERFAIGV-GEEFKSARTA----RELNLIASDPDETHAFKVTNYMAL 375
Query: 344 TDIVDALGDRIFGLEGSHAENESSFGLEMSQIGFSTHRLKDG-ILFGMVGAYDWGGSVLW 402
++ L I +EG+ + + +++QIGFS L + +L G VGA+DW G L
Sbjct: 376 DGLLSKLRYNIISMEGTVGD---ALHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALL 432
Query: 403 LEGGHRL--FPPRMALEDEFPPALQNHAAYLGYSVSSMLLRGGRRLFLSGAPRFRHRGKV 460
+ R F + A A Q +YLGY+V+ +L + +++GAPR++H G V
Sbjct: 433 YDTRSRRGRFLNQTAAAAADAEAAQY--SYLGYAVA-VLHKTCSLSYIAGAPRYKHHGAV 489
Query: 461 IAFQLKKDGA-VRVAQSLQGEQIGSYFGSELCPLDTDRDGTTDVLLVAAPMFLGPQNKET 519
F+L+K+G L+GEQ+GSYFGSELCP+D D DG+TD LLVAAP + + E
Sbjct: 490 --FELQKEGREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFY--HVHGEE 545
Query: 520 GRVYVYLVGQQS-LLTLQGTLQPEPP-QDARFGFAMGALPDLNQDGFADVAVGAPLE--- 574
GRVYVY + +Q +L L P +ARFGFAM A+ DL+QD DVA+GAPLE
Sbjct: 546 GRVYVYRLSEQDGSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFG 605
Query: 575 --DGHQ-GALYLYHGTQSGVRPHPAQRIAAASMPHALSYFGRSVDGRLDLDGDDLVDVAV 631
DG G++Y+Y+G G+ P+QRI A+++ L YFG S+ G D+ GD L D+ V
Sbjct: 606 ADDGASFGSVYIYNGHWDGLSASPSQRIRASTVAPGLQYFGMSMAGGFDISGDGLADITV 665
Query: 632 GAQGAAILLSSRPIVHLTPSLEVTPQAISVVQRDCRRRGQEAVCLTAALCFQVTSRTPGR 691
G G A++ SRP+V L S+ TP A+ + G V + LCF+++S T
Sbjct: 666 GTLGQAVVFRSRPVVRLKVSMAFTPSALPI--------GFNGV-VNVRLCFEISSVTTAS 716
Query: 692 WD--HQFYMRFTASLDEWTAGARAAFDGSGQRLSPRRLRLSVGNVTCEQLHF----HVLD 745
+ + FT +D R L R S G+ CE L L
Sbjct: 717 ESGLREALLNFTLDVDVGKQRRRLQCSDVRSCLGCLR-EWSSGSQLCEDLLLMPTEGELC 775
Query: 746 TSDYLRPVALTVTFALD----NTTKPGPVLNEGSPTSIQKLVPFSKDCGPDNECVTDLVL 801
D ++ V++ L T P P+L+ + +P+ K C CV +L L
Sbjct: 776 EEDCFSNASVKVSYQLQTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQL 835
Query: 802 QVNMDIRGSRKAPFVVRGGRRKVLVSTTLENRKENAYNTSLSLIFSRNLHLASLTPQRES 861
+ + +V G +++ ++ L N E++Y TS++L + RNL L + Q+
Sbjct: 836 ATTVSQQE------LVVGLTKELTLNINLTNSGEDSYMTSMALNYPRNLQLKRM--QKPP 887
Query: 862 PIKVECAAPSAHARL----CSVGHPVF-QTGAKVTFLLEFE 897
++C P A + C +GHPV ++ A V+ + + E
Sbjct: 888 SPNIQCDDPQPVASVLIMNCRIGHPVLKRSSAHVSVVWQLE 928
Score = 30.8 bits (68), Expect = 7.9
Identities = 15/32 (46%), Positives = 22/32 (68%)
Query: 1122 SLWILIGSVLGGLLLLALLVFCLWKLGFFAHK 1153
SL I+I +GGLL+L +++ L+K GFF K
Sbjct: 1124 SLPIIIKGSVGGLLVLIVILVILFKCGFFKRK 1155
>gi|52485941 integrin, alpha 9 precursor [Homo sapiens]
Length = 1035
Score = 235 bits (600), Expect = 2e-61
Identities = 214/844 (25%), Positives = 374/844 (44%), Gaps = 71/844 (8%)
Query: 376 GFSTHRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEFPPALQNHAAYLGYSV 435
GF T L ++ G G++ W G++ L + + L DE + YLGY+V
Sbjct: 200 GFFTEEL---VVMGAPGSFYWAGTIKVLNLTDNTY---LKLNDEV--IMNRRYTYLGYAV 251
Query: 436 SSMLLRGGRRL-FLSGAPRFRHRGKVIAFQL-KKDGAVRVAQSLQGEQIGSYFGSELCPL 493
++ + + GAP+ + GKV F+ ++ G + G+++GSYFGS LC +
Sbjct: 252 TAGHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAV 311
Query: 494 DTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQPEPPQDARFGFAM 553
D + DG +D LLV APMF + ++ G+V VY+ L Q L + +A FG ++
Sbjct: 312 DLNGDGLSD-LLVGAPMF--SEIRDEGQVTVYINRGNGALEEQLALTGDGAYNAHFGESI 368
Query: 554 GALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAASMPHALSYFGR 613
+L DL+ DGF DVA+GAP ED GA+Y+YHG G+ P + +++ + L FG+
Sbjct: 369 ASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIVPQYSMKLSGQKINPVLRMFGQ 428
Query: 614 SVDGRLDLDGDDLVDVAVGA--QGAAILLSSRPIVHLTPSLEVTPQAISVVQRDCRRRGQ 671
S+ G +D+DG+ DV VGA + +LL +RP++ + S+ P +I++ C Q
Sbjct: 429 SISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDVSI-FLPGSINITAPQCHDGQQ 487
Query: 672 EAVCLTAALCFQVTSR-TPGRWDHQFYMRFTASLDEWTAGARAAFDGSGQRLS--PRRLR 728
CL CF + PG + + + E R F G+ + +L+
Sbjct: 488 PVNCLNVTTCFSFHGKHVPGEIGLNYVLMADVAKKEKGQMPRVYFVLLGETMGQVTEKLQ 547
Query: 729 LSVGNVTCEQLHFHV-LDTSDYLRPVALTVTFALDNTTKP---------GPVL--NEGSP 776
L+ TC HV D + P+ ++L PVL +G
Sbjct: 548 LTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEERELPPLTPVLRWKKGQK 607
Query: 777 TSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRG-SRKAPFVVRGGRRKVLVSTTLENRKE 835
+ + F ++C + +C DL LQ + + K ++ G + + ++ ++ N +
Sbjct: 608 IAQKNQTVFERNCRSE-DCAADLQLQGKLLLSSMDEKTLYLALGAVKNISLNISISNLGD 666
Query: 836 NAYNTSLSLIFSRNLHLASLTPQRESPIKVECAAPSAHARLCSVGHPVFQTGAKVTFLLE 895
+AY+ ++S SR L ++ + E + + C + CSVG P ++ +K F +
Sbjct: 667 DAYDANVSFNVSRELFFINMWQKEE--MGISCELLESDFLKCSVGFPFMRSKSKYEFSVI 724
Query: 896 FEFSCSSLLSQVF-VKLTASSDSLERNGTLQDNTAQTSAYIQYEPHL----LFSSESTLH 950
F+ S S +V +TA S + ER+ +L DNT + +E + S S ++
Sbjct: 725 FDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVY 784
Query: 951 RYEVHPYGTLPVGP----GPEFKTTLRVQNLGCYVVSGLIISALLP-AVAHGGNYFLSLS 1005
V + + TL+V N G + G +S P ++ GG +
Sbjct: 785 GESVDAANFIQLDDLECHFQPINITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEMFHVQ 844
Query: 1006 QVIT--NNASCIVQNLTEPPGPPVHPEELQHT------------NRLNGSNTQCQVVRCH 1051
+++ +C Q P P E + HT C C+
Sbjct: 845 EMVVGQEKGNCSFQKNPTPCIIPQEQENIFHTIFAFFTKSGRKVLDCEKPGISCLTAHCN 904
Query: 1052 LGQLAKGTEVSVGLLRLVHNEFFRRAKFKSLTVVSTFELGTEEGSVLQLTEASRWSESLL 1111
LAK ++ + L++ E ++ + +S ++ + L++ E + + +
Sbjct: 905 FSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVD--PALRVVEIAHGNPEEV 962
Query: 1112 EVV-------QTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFF--AHKKIPEEEKRE 1162
VV + R ++ WI+ S+L G+L+ LL LWK+GFF +K+I E EK
Sbjct: 963 TVVFEALHNLEPRGYVVG-WIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIEAEKNR 1021
Query: 1163 EKLE 1166
++ E
Sbjct: 1022 KENE 1025
Score = 58.9 bits (141), Expect = 3e-08
Identities = 47/158 (29%), Positives = 68/158 (43%), Gaps = 13/158 (8%)
Query: 9 LFLPLVFLTGLCSPFNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGAPWD----G 64
L L LV +NLD P F GP ++ FGY+VL+H RW+LVGAP
Sbjct: 16 LLLALVVAGIPAGAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRWVLVGAPKADSKYS 75
Query: 65 PSGDRRGDVYRCPVGGAHNAPC-----AKGHLGDYQLGNS-SHPAVNMHLGMSLL-ETDG 117
PS G V++C V + C A+G G + + +G+SL +
Sbjct: 76 PSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEWMGVSLARQPKA 135
Query: 118 DGGFMACAPLWSRAC--GSSVFSSGICARVDASFQPQG 153
DG +ACA W + G C + ++ Q +G
Sbjct: 136 DGRVLACAHRWKNIYYEADHILPHGFCYIIPSNLQAKG 173
>gi|67191027 integrin alpha 4 precursor [Homo sapiens]
Length = 1032
Score = 209 bits (531), Expect = 2e-53
Identities = 212/848 (25%), Positives = 373/848 (43%), Gaps = 84/848 (9%)
Query: 374 QIGFSTHRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEFPPALQNHAAYLGY 433
Q G S+ KD I+ G G+ W GS+ + + +++ +YLGY
Sbjct: 199 QAGISSFYTKDLIVMGAPGSSYWTGSLFVYNITTNKYKAFLDKQNQV-----KFGSYLGY 253
Query: 434 SVSSMLLRGGRRL-FLSGAPRFRHRGKVIAFQLKKDGAVRVAQSLQGEQIGSYFGSELCP 492
SV + R + GAP+ GK F + + + + ++G+++GSYFG+ +C
Sbjct: 254 SVGAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEK-ELNILHEMKGKKLGSYFGASVCA 312
Query: 493 LDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLL--TLQGTLQPEPPQDARFG 550
+D + DG +D LLV APM +E GRV+VY+ + ++ L ARFG
Sbjct: 313 VDLNADGFSD-LLVGAPM--QSTIREEGRVFVYINSGSGAVMNAMETNLVGSDKYAARFG 369
Query: 551 FAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAASMPHALSY 610
++ L D++ DGF DVA+GAP ED QGA+Y+Y+G G+ +QRI + +LS
Sbjct: 370 ESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGISSTFSQRIEGLQISKSLSM 429
Query: 611 FGRSVDGRLDLDGDDLVDVAVGA--QGAAILLSSRPIVHLTPSLEVTPQAISVVQRDCRR 668
FG+S+ G++D D + VDVAVGA +A+LL +RP+V + SL P++++ + DC
Sbjct: 430 FGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLS-HPESVNRTKFDCVE 488
Query: 669 RGQEAVCLTAALCFQVTSRTPGRWDHQFYMRFTASLDEWTAGARAAFDGSG-QRLSPRRL 727
G +VC+ LCF + + FY + + R F +G + +
Sbjct: 489 NGWPSVCIDLTLCFSYKGKEVPGYIVLFYNMSLDVNRKAESPPRFYFSSNGTSDVITGSI 548
Query: 728 RLSVGNVTCE-QLHFHVLDTSDYLRPVALTVTFAL----------DNTTKPGPVLNEGSP 776
++S C F D D L P+ + + L + P+L +
Sbjct: 549 QVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQPILQQKKE 608
Query: 777 TSI-QKLVPFSKDCGPDNECVTDLVLQVNMD-IRGSRKAPFVVRGGRRKVLVSTTLENRK 834
I +K + F++ C +N C DL + + ++ ++ G + ++++ +L N
Sbjct: 609 KDIMKKTINFARFCAHEN-CSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNVSLFNAG 667
Query: 835 ENAYNTSLSLIFSRNLHLASLTPQRESPIKVECAAPSAHARL-CSVGHPVFQ--TGAKVT 891
++AY T+L + L+ + E I E S +L CS+G+ + ++
Sbjct: 668 DDAYETTLHVKLPVGLYFIKILELEEKQINCEVTDNSGVVQLDCSIGYIYVDHLSRIDIS 727
Query: 892 FLLEFEFSCSSLLSQVFVKLTASSDSLERNGTLQDNTAQTSAYIQYEPHLLFSSESTLHR 951
FLL+ S S + + + A+ ++ E L+ + + ++YE L T+H
Sbjct: 728 FLLDVS-SLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKL------TVHG 780
Query: 952 YEVHP----YGTLPVGPGPE------FKTTLRVQNLGCYVVSGLIISALLP-AVAHGGNY 1000
+ V+P YG+ PE T V N G + + + ++P + + +
Sbjct: 781 F-VNPTSFVYGSNDENE-PETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQTDK 838
Query: 1001 FLSLSQVITNNASCIVQNLTEPPGPPVHPEELQHTNRL--------------NGSNTQCQ 1046
++ V T C +N +Q + ++ C
Sbjct: 839 LFNILDVQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKRLLYCIKADPHCL 898
Query: 1047 VVRCHLGQLAKGTEVSVGLLRLVHNEFFRRAKFKSLTVVST--FEL---GTEEGS--VLQ 1099
C+ G++ G E S VH + R + S FE+ G E + V++
Sbjct: 899 NFLCNFGKMESGKEAS------VHIQLEGRPSILEMDETSALKFEIRATGFPEPNPRVIE 952
Query: 1100 LTEASRWSESLLEVV--QTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFF--AHKKI 1155
L + + LLE + Q ++ I+ S+L GL++L L+ + +WK GFF +K I
Sbjct: 953 LNKDENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSI 1012
Query: 1156 PEEEKREE 1163
+EE R +
Sbjct: 1013 LQEENRRD 1020
Score = 57.8 bits (138), Expect = 6e-08
Identities = 38/116 (32%), Positives = 51/116 (43%), Gaps = 9/116 (7%)
Query: 22 PFNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGAP---W-DGPSGDRRGDVYRCP 77
P+N+D L+ GP FGYSV+ H G RW+LVGAP W S G +YRC
Sbjct: 33 PYNVDTESALLYQGPHNTLFGYSVVLHSHGANRWLLVGAPTANWLANASVINPGAIYRCR 92
Query: 78 VGGAHNAPCAKGHLGDYQLGNSSHPAV----NMHLGMSLLETDGD-GGFMACAPLW 128
+G C + LG + N LG++L G+ G + C W
Sbjct: 93 IGKNPGQTCEQLQLGSPNGEPCGKTCLEERDNQWLGVTLSRQPGENGSIVTCGHRW 148
>gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [Homo
sapiens]
Length = 1073
Score = 188 bits (477), Expect = 3e-47
Identities = 226/884 (25%), Positives = 369/884 (41%), Gaps = 131/884 (14%)
Query: 386 ILFGMVGAYDWGGSVLWLEGGHRLF--------PPRMALEDEFPPALQNHAA--YLGYSV 435
I+FG G Y+W G V + + F P + E E +L A YLG+S+
Sbjct: 203 IVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPANSYLGFSL 262
Query: 436 SSM--LLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSL-QGEQIGSYFGSELCP 492
S ++ F+SGAPR H G V+ + A + + + GE + S FG ++
Sbjct: 263 DSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAV 322
Query: 493 LDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQPEPPQDARFGFA 552
+D ++DG D++ + AP + + G VYVY+ QQ ++ +D+ FG A
Sbjct: 323 VDLNKDGWQDIV-IGAPQYFDRDGEVGGAVYVYM-NQQGRWNNVKPIRLNGTKDSMFGIA 380
Query: 553 MGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAASMPHALSYFG 612
+ + D+NQDG+ D+AVGAP +D G +++YHG+ +G+ P Q + S YFG
Sbjct: 381 VKNIGDINQDGYPDIAVGAPYDD--LGKVFIYHGSANGINTKPTQVLKGIS-----PYFG 433
Query: 613 RSVDGRLDLDGDDLVDVAVGAQGAAI-LLSSRPIVHLTPSLEVTPQAISVVQRDCRRRGQ 671
S+ G +DLD + DVAVG+ ++ + SRP++++ ++ VTP I + Q+
Sbjct: 434 YSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTA-CGAP 492
Query: 672 EAVCLTAALCFQVTSRTPG-RWDHQFYMRFTASLDEWTAGARAAFDGSGQRLSPR----- 725
+CL CF+ T+ G A + +G + Q P+
Sbjct: 493 SGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQEL 552
Query: 726 RLRLSVGNVTCEQLHFHVLDTSDYLRPVALTVTFALDNTTKPG---------PVLNEGSP 776
L+ V E+ + + D LRP+ +T + + + P+LN P
Sbjct: 553 TLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEP 612
Query: 777 TSIQKLVPFSKD-CGPDNECVTDLVLQVNMDIRGSRK-----------APFVVRGGRRKV 824
+ V F K+ CG DN C ++L L+ R + P +V ++ +
Sbjct: 613 KTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDI 672
Query: 825 LVSTTLENRKEN----------AYNTSLSLIFSRNLHLASLTPQRESPIK-VECAAPSAH 873
+ T+ N N A+ L F L ++ R P K + C A
Sbjct: 673 ALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNG 732
Query: 874 ARL-CSVGHPVFQTGAKVTFLL-----EFEFSCSSLLSQVFVKLTASSDSLERNGTLQDN 927
++ C +G+P F+ + VTF L E F L + +KL +S+ QDN
Sbjct: 733 SQADCELGNP-FKRNSNVTFYLVLSTTEVTFDTPDL--DINLKLETTSN--------QDN 781
Query: 928 TAQTSAYIQYEPHLLFSSESTLHRYEVHPYGTLPVGP---------GPEFKTTLRVQNLG 978
A +A + LL S +V+ GT+ VG G + RV NLG
Sbjct: 782 LAPITAKAKVVIELLLSVSGVAKPSQVYFGGTV-VGEQAMKSEDEVGSLIEYEFRVINLG 840
Query: 979 CYV--VSGLIISALLPAVAHGGNYFLSLSQVIT---NNASCIVQ------NLTEPPGPPV 1027
+ + ++ P G + L L +V + +C Q NLTE
Sbjct: 841 KPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRK 900
Query: 1028 HPEELQ---HTNR------------LNGS-NTQCQVVRCHLGQLAKGTEVSVGLL---RL 1068
E + NR LN S N C +RC L +G + L+ RL
Sbjct: 901 KREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPL----RGLDSKASLILRSRL 956
Query: 1069 VHNEFFRR-AKFKSLTV-VSTFELGTEEGSVLQLTEASRWSESLLEVVQTRPIL----IS 1122
++ F +K L + + F T ++L A ++ + V ++ + +
Sbjct: 957 WNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAG--TQVRVTVFPSKTVAQYSGVP 1014
Query: 1123 LWILIGSVLGGLLLLALLVFCLWKLGFFAHKKIPEEEKREEKLE 1166
WI++ ++L G+L+LALLVF LWK GFF K + K E
Sbjct: 1015 WWIILVAILAGILMLALLVFILWKCGFFKRNKKDHYDATYHKAE 1058
>gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [Homo
sapiens]
Length = 1091
Score = 187 bits (475), Expect = 5e-47
Identities = 224/879 (25%), Positives = 368/879 (41%), Gaps = 131/879 (14%)
Query: 386 ILFGMVGAYDWGGSVLWLEGGHRLF--------PPRMALEDEFPPALQNHAA--YLGYSV 435
I+FG G Y+W G V + + F P + E E +L A YLG+S+
Sbjct: 203 IVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPANSYLGFSL 262
Query: 436 SSM--LLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSL-QGEQIGSYFGSELCP 492
S ++ F+SGAPR H G V+ + A + + + GE + S FG ++
Sbjct: 263 DSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAV 322
Query: 493 LDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQPEPPQDARFGFA 552
+D ++DG D++ + AP + + G VYVY+ QQ ++ +D+ FG A
Sbjct: 323 VDLNKDGWQDIV-IGAPQYFDRDGEVGGAVYVYM-NQQGRWNNVKPIRLNGTKDSMFGIA 380
Query: 553 MGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAASMPHALSYFG 612
+ + D+NQDG+ D+AVGAP +D G +++YHG+ +G+ P Q + S YFG
Sbjct: 381 VKNIGDINQDGYPDIAVGAPYDD--LGKVFIYHGSANGINTKPTQVLKGIS-----PYFG 433
Query: 613 RSVDGRLDLDGDDLVDVAVGAQGAAI-LLSSRPIVHLTPSLEVTPQAISVVQRDCRRRGQ 671
S+ G +DLD + DVAVG+ ++ + SRP++++ ++ VTP I + Q+
Sbjct: 434 YSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTA-CGAP 492
Query: 672 EAVCLTAALCFQVTSRTPG-RWDHQFYMRFTASLDEWTAGARAAFDGSGQRLSPR----- 725
+CL CF+ T+ G A + +G + Q P+
Sbjct: 493 SGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQEL 552
Query: 726 RLRLSVGNVTCEQLHFHVLDTSDYLRPVALTVTFALDNTTKPG---------PVLNEGSP 776
L+ V E+ + + D LRP+ +T + + + P+LN P
Sbjct: 553 TLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEP 612
Query: 777 TSIQKLVPFSKD-CGPDNECVTDLVLQVNMDIRGSRK-----------APFVVRGGRRKV 824
+ V F K+ CG DN C ++L L+ R + P +V ++ +
Sbjct: 613 KTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDI 672
Query: 825 LVSTTLENRKEN----------AYNTSLSLIFSRNLHLASLTPQRESPIK-VECAAPSAH 873
+ T+ N N A+ L F L ++ R P K + C A
Sbjct: 673 ALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNG 732
Query: 874 ARL-CSVGHPVFQTGAKVTFLL-----EFEFSCSSLLSQVFVKLTASSDSLERNGTLQDN 927
++ C +G+P F+ + VTF L E F L + +KL +S+ QDN
Sbjct: 733 SQADCELGNP-FKRNSNVTFYLVLSTTEVTFDTPDL--DINLKLETTSN--------QDN 781
Query: 928 TAQTSAYIQYEPHLLFSSESTLHRYEVHPYGTLPVGP---------GPEFKTTLRVQNLG 978
A +A + LL S +V+ GT+ VG G + RV NLG
Sbjct: 782 LAPITAKAKVVIELLLSVSGVAKPSQVYFGGTV-VGEQAMKSEDEVGSLIEYEFRVINLG 840
Query: 979 CYV--VSGLIISALLPAVAHGGNYFLSLSQVIT---NNASCIVQ------NLTEPPGPPV 1027
+ + ++ P G + L L +V + +C Q NLTE
Sbjct: 841 KPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRK 900
Query: 1028 HPEELQ---HTNR------------LNGS-NTQCQVVRCHLGQLAKGTEVSVGLL---RL 1068
E + NR LN S N C +RC L +G + L+ RL
Sbjct: 901 KREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPL----RGLDSKASLILRSRL 956
Query: 1069 VHNEFFRR-AKFKSLTV-VSTFELGTEEGSVLQLTEASRWSESLLEVVQTRPIL----IS 1122
++ F +K L + + F T ++L A ++ + V ++ + +
Sbjct: 957 WNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAG--TQVRVTVFPSKTVAQYSGVP 1014
Query: 1123 LWILIGSVLGGLLLLALLVFCLWKLGFFAHKKIPEEEKR 1161
WI++ ++L G+L+LALLVF LWK GFF + + R
Sbjct: 1015 WWIILVAILAGILMLALLVFILWKCGFFKRSRYDDSVPR 1053
>gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]
Length = 1137
Score = 185 bits (470), Expect = 2e-46
Identities = 226/883 (25%), Positives = 378/883 (42%), Gaps = 133/883 (15%)
Query: 386 ILFGMVGAYDWGGSVLWLEGGHRLFPPRMALE-----DEFPPALQNHA--AYLGYSVSSM 438
+LFG G Y+W G +L++ P ++ + D P + A +YLG+S+ S
Sbjct: 212 LLFGAPGTYNWKG-LLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSG 270
Query: 439 --LLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQS--LQGEQIGSYFGSELCPLD 494
L+R F++GAPR H+G V+ L+KD A R+ L GE++ S FG L D
Sbjct: 271 KGLVRAEELSFVAGAPRANHKGAVVI--LRKDSASRLVPEVMLSGERLTSGFGYSLAVAD 328
Query: 495 TDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQPEPPQDARFGFAMG 554
+ DG D L+V AP F Q + G VYVYL Q L+ D+ FG ++
Sbjct: 329 LNSDGWPD-LIVGAPYFFERQEELGGAVYVYL-NQGGHWAGISPLRLCGSPDSMFGISLA 386
Query: 555 ALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAASMPHALSYFGRS 614
L DLNQDGF D+AVGAP + G +++YHG+ GV P+Q + ++ + FG S
Sbjct: 387 VLGDLNQDGFPDIAVGAPFDG--DGKVFIYHGSSLGVVAKPSQVLEGEAV--GIKSFGYS 442
Query: 615 VDGRLDLDGDDLVDVAVGA-QGAAILLSSRPIVHLTPSLEVTPQAISVVQRDCRRRGQEA 673
+ G LD+DG+ D+ VG+ A+L +RPI+H++ + + P++I + Q +C G +
Sbjct: 443 LSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNC--AGGHS 500
Query: 674 VCLTAALCFQVTSRTPGRWDHQFYMRFT--ASLDEWTAGARAAFDGSGQRLSPRRLRLSV 731
VC+ +CF + P + + + A D G + L + + S
Sbjct: 501 VCVDLRVCFSYIA-VPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQAS- 558
Query: 732 GNVTCEQLHFHVL---------DTSDYLRPVALTVTFALD----NTTKPG-------PVL 771
G V + H V + D LR + +T++++L PG P+L
Sbjct: 559 GTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPIL 618
Query: 772 NEGSPTSIQKLVPFSKD-CGPDNECVTDLVL---------------QVNMDIRGSRKAPF 815
N P++ + + F K CG D C ++L L + MD+ G+ A F
Sbjct: 619 NAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGT-TALF 677
Query: 816 VVRG----GRRKVLVSTTLENRK-----ENAYNTSLSLIFSRNLHLASLTPQRESPIKVE 866
+ G G ++ + + + ++A+ L ++ +LH + + + +
Sbjct: 678 ALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLC 737
Query: 867 CAAPSAHARLCSVGHPVFQTGAKVTFLLEFEFSCSSL-LSQVFVKLTASSDSLERNGTLQ 925
+ +A C +G+P+ + GA+VTF L S S+ +++ V+L ++ S + L
Sbjct: 738 LSNENASHVECELGNPM-KRGAQVTFYLILSTSGISIETTELEVELLLATISEQE---LH 793
Query: 926 DNTAQTSAYIQYE--------PHLLFSSESTLHRYEVHPYGTLPVGPGPEFKTTLRVQNL 977
+A+ +I+ P LF S + R E VG +++ T+ Q
Sbjct: 794 PVSARARVFIELPLSIAGMAIPQQLFF--SGVVRGERAMQSERDVGSKVKYEVTVSNQGQ 851
Query: 978 GCYVVSGLIISALLPAVAHGGNYFLSLSQVITNNASCIVQNLTEPPGPPV---------- 1027
+ ++ + P G + L QV Q P P +
Sbjct: 852 SLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDR 911
Query: 1028 ------HPEELQHTNRLNGS----------------------NTQCQVVRCHLGQLAKGT 1059
PE+ + R S C V C L +
Sbjct: 912 RRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAA 971
Query: 1060 EVSVGLLRLVHNEFFRR-AKFKSLTVVSTFELGTEEGSV--LQLTEASRWSESLLEVVQT 1116
+ V RL ++ F + KSL V+ + T + S+ L L +AS ++ +
Sbjct: 972 VLHV-WGRLWNSTFLEEYSAVKSLEVIVRANI-TVKSSIKNLMLRDASTVIPVMVYLDPM 1029
Query: 1117 RPIL--ISLWILIGSVLGGLLLLALLVFCLWKLGFFAHKKIPE 1157
+ + W+++ +VL GLL+LALLV LWK+GFF K PE
Sbjct: 1030 AVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPE 1072
Score = 38.1 bits (87), Expect = 0.049
Identities = 32/110 (29%), Positives = 44/110 (40%), Gaps = 9/110 (8%)
Query: 23 FNLDEHHPRLFPGPPEAEFGYSVLQH---VGGGQRWMLVGAP----WDGPSGDRRGDVYR 75
FNLD G P + FG+SV H Q W+LVGAP G +R G ++
Sbjct: 34 FNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFA 93
Query: 76 CPVGGAHNAPCAKGHLGDYQLGNSSHPAVNMHLGMSLLETDGDGGFMACA 125
CP+ C + + D N LG+S+ G + CA
Sbjct: 94 CPL-SLEETDCYRVDI-DQGADMQKESKENQWLGVSVRSQGPGGKIVTCA 141
>gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]
Length = 1044
Score = 184 bits (467), Expect = 4e-46
Identities = 229/886 (25%), Positives = 375/886 (42%), Gaps = 135/886 (15%)
Query: 386 ILFGMVGAYDWGGSV---LWLEGGHRLF-----PPRMALEDEFPPALQNHAA--YLGYSV 435
+LFG G Y+W G+ L +G L P E E P L A Y G+S+
Sbjct: 115 LLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGFSI 174
Query: 436 SSM--LLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQS--LQGEQIGSYFGSELC 491
S L+R F++GAPR H+G V+ L+KD A R+ L GE++ S FG L
Sbjct: 175 DSGKGLVRAEELSFVAGAPRANHKGAVVI--LRKDSASRLVPEVMLSGERLTSGFGYSLA 232
Query: 492 PLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQPEPPQDARFGF 551
D + DG D L+V AP F Q + G VYVYL Q L+ D+ FG
Sbjct: 233 VADLNSDGWPD-LIVGAPYFFERQEELGGAVYVYL-NQGGHWAGISPLRLCGSPDSMFGI 290
Query: 552 AMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAASMPHALSYF 611
++ L DLNQDGF D+AVGAP + G +++YHG+ GV P+Q + ++ + F
Sbjct: 291 SLAVLGDLNQDGFPDIAVGAPFDG--DGKVFIYHGSSLGVVAKPSQVLEGEAV--GIKSF 346
Query: 612 GRSVDGRLDLDGDDLVDVAVGA-QGAAILLSSRPIVHLTPSLEVTPQAISVVQRDCRRRG 670
G S+ G LD+DG+ D+ VG+ A+L +RPI+H++ + + P++I + Q +C G
Sbjct: 347 GYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNC--AG 404
Query: 671 QEAVCLTAALCFQVTSRTPGRWDHQFYMRFT--ASLDEWTAGARAAFDGSGQRLSPRRLR 728
+VC+ +CF + P + + + A D G + L + +
Sbjct: 405 GHSVCVDLRVCFSYIA-VPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQ 463
Query: 729 LSVGNVTCEQLHFHVL---------DTSDYLRPVALTVTFALD----NTTKPG------- 768
S G V + H V + D LR + +T++++L PG
Sbjct: 464 AS-GTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVA 522
Query: 769 PVLNEGSPTSIQKLVPFSKD-CGPDNECVTDLVL---------------QVNMDIRGSRK 812
P+LN P++ + + F K CG D C ++L L + MD+ G+
Sbjct: 523 PILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGT-T 581
Query: 813 APFVVRG----GRRKVLVSTTLENRK-----ENAYNTSLSLIFSRNLHLASLTPQRESPI 863
A F + G G ++ + + + ++A+ L ++ +LH + + +
Sbjct: 582 ALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEK 641
Query: 864 KVECAAPSAHARLCSVGHPVFQTGAKVTFLLEFEFSCSSL-LSQVFVKLTASSDSLERNG 922
+ + +A C +G+P+ + GA+VTF L S S+ +++ V+L ++ S +
Sbjct: 642 PLCLSNENASHVECELGNPM-KRGAQVTFYLILSTSGISIETTELEVELLLATISEQE-- 698
Query: 923 TLQDNTAQTSAYIQYE--------PHLLFSSESTLHRYEVHPYGTLPVGPGPEFKTTLRV 974
L +A+ +I+ P LF S + R E VG +++ T+
Sbjct: 699 -LHPVSARARVFIELPLSIAGMAIPQQLFF--SGVVRGERAMQSERDVGSKVKYEVTVSN 755
Query: 975 QNLGCYVVSGLIISALLPAVAHGGNYFLSLSQVITNNASCIVQNLTEPPGPPV------- 1027
Q + ++ + P G + L QV Q P P +
Sbjct: 756 QGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDS 815
Query: 1028 ---------HPEELQHTNRLNGS----------------------NTQCQVVRCHLGQLA 1056
PE+ + R S C V C L
Sbjct: 816 RDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFD 875
Query: 1057 KGTEVSVGLLRLVHNEFFRR-AKFKSLTVVSTFELGTEEGSV--LQLTEASRWSESLLEV 1113
+ + V RL ++ F + KSL V+ + T + S+ L L +AS ++ +
Sbjct: 876 RAAVLHV-WGRLWNSTFLEEYSAVKSLEVIVRANI-TVKSSIKNLMLRDASTVIPVMVYL 933
Query: 1114 VQTRPIL--ISLWILIGSVLGGLLLLALLVFCLWKLGFFAHKKIPE 1157
+ + W+++ +VL GLL+LALLV LWK+GFF K PE
Sbjct: 934 DPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPE 979
>gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]
Length = 1141
Score = 184 bits (467), Expect = 4e-46
Identities = 229/886 (25%), Positives = 375/886 (42%), Gaps = 135/886 (15%)
Query: 386 ILFGMVGAYDWGGSV---LWLEGGHRLF-----PPRMALEDEFPPALQNHAA--YLGYSV 435
+LFG G Y+W G+ L +G L P E E P L A Y G+S+
Sbjct: 212 LLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGFSI 271
Query: 436 SSM--LLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQS--LQGEQIGSYFGSELC 491
S L+R F++GAPR H+G V+ L+KD A R+ L GE++ S FG L
Sbjct: 272 DSGKGLVRAEELSFVAGAPRANHKGAVVI--LRKDSASRLVPEVMLSGERLTSGFGYSLA 329
Query: 492 PLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQPEPPQDARFGF 551
D + DG D L+V AP F Q + G VYVYL Q L+ D+ FG
Sbjct: 330 VADLNSDGWPD-LIVGAPYFFERQEELGGAVYVYL-NQGGHWAGISPLRLCGSPDSMFGI 387
Query: 552 AMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAASMPHALSYF 611
++ L DLNQDGF D+AVGAP + G +++YHG+ GV P+Q + ++ + F
Sbjct: 388 SLAVLGDLNQDGFPDIAVGAPFDG--DGKVFIYHGSSLGVVAKPSQVLEGEAV--GIKSF 443
Query: 612 GRSVDGRLDLDGDDLVDVAVGA-QGAAILLSSRPIVHLTPSLEVTPQAISVVQRDCRRRG 670
G S+ G LD+DG+ D+ VG+ A+L +RPI+H++ + + P++I + Q +C G
Sbjct: 444 GYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNC--AG 501
Query: 671 QEAVCLTAALCFQVTSRTPGRWDHQFYMRFT--ASLDEWTAGARAAFDGSGQRLSPRRLR 728
+VC+ +CF + P + + + A D G + L + +
Sbjct: 502 GHSVCVDLRVCFSYIA-VPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQ 560
Query: 729 LSVGNVTCEQLHFHVL---------DTSDYLRPVALTVTFALD----NTTKPG------- 768
S G V + H V + D LR + +T++++L PG
Sbjct: 561 AS-GTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVA 619
Query: 769 PVLNEGSPTSIQKLVPFSKD-CGPDNECVTDLVL---------------QVNMDIRGSRK 812
P+LN P++ + + F K CG D C ++L L + MD+ G+
Sbjct: 620 PILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGT-T 678
Query: 813 APFVVRG----GRRKVLVSTTLENRK-----ENAYNTSLSLIFSRNLHLASLTPQRESPI 863
A F + G G ++ + + + ++A+ L ++ +LH + + +
Sbjct: 679 ALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEK 738
Query: 864 KVECAAPSAHARLCSVGHPVFQTGAKVTFLLEFEFSCSSL-LSQVFVKLTASSDSLERNG 922
+ + +A C +G+P+ + GA+VTF L S S+ +++ V+L ++ S +
Sbjct: 739 PLCLSNENASHVECELGNPM-KRGAQVTFYLILSTSGISIETTELEVELLLATISEQE-- 795
Query: 923 TLQDNTAQTSAYIQYE--------PHLLFSSESTLHRYEVHPYGTLPVGPGPEFKTTLRV 974
L +A+ +I+ P LF S + R E VG +++ T+
Sbjct: 796 -LHPVSARARVFIELPLSIAGMAIPQQLFF--SGVVRGERAMQSERDVGSKVKYEVTVSN 852
Query: 975 QNLGCYVVSGLIISALLPAVAHGGNYFLSLSQVITNNASCIVQNLTEPPGPPV------- 1027
Q + ++ + P G + L QV Q P P +
Sbjct: 853 QGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDS 912
Query: 1028 ---------HPEELQHTNRLNGS----------------------NTQCQVVRCHLGQLA 1056
PE+ + R S C V C L
Sbjct: 913 RDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFD 972
Query: 1057 KGTEVSVGLLRLVHNEFFRR-AKFKSLTVVSTFELGTEEGSV--LQLTEASRWSESLLEV 1113
+ + V RL ++ F + KSL V+ + T + S+ L L +AS ++ +
Sbjct: 973 RAAVLHV-WGRLWNSTFLEEYSAVKSLEVIVRANI-TVKSSIKNLMLRDASTVIPVMVYL 1030
Query: 1114 VQTRPIL--ISLWILIGSVLGGLLLLALLVFCLWKLGFFAHKKIPE 1157
+ + W+++ +VL GLL+LALLV LWK+GFF K PE
Sbjct: 1031 DPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPE 1076
Score = 38.1 bits (87), Expect = 0.049
Identities = 32/110 (29%), Positives = 44/110 (40%), Gaps = 9/110 (8%)
Query: 23 FNLDEHHPRLFPGPPEAEFGYSVLQH---VGGGQRWMLVGAP----WDGPSGDRRGDVYR 75
FNLD G P + FG+SV H Q W+LVGAP G +R G ++
Sbjct: 34 FNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFA 93
Query: 76 CPVGGAHNAPCAKGHLGDYQLGNSSHPAVNMHLGMSLLETDGDGGFMACA 125
CP+ C + + D N LG+S+ G + CA
Sbjct: 94 CPL-SLEETDCYRVDI-DQGADMQKESKENQWLGVSVRSQGPGGKIVTCA 141
>gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]
Length = 1051
Score = 179 bits (453), Expect = 2e-44
Identities = 158/592 (26%), Positives = 268/592 (45%), Gaps = 55/592 (9%)
Query: 372 MSQIGFSTHRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEFPPALQNHAAYL 431
M Q+G S ++ + FG GAY+W G+ ++ + E L Y+
Sbjct: 196 MCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKDPEDQGNL-----YI 250
Query: 432 GYS--VSSMLLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSLQGEQIGSYFGSE 489
GY+ V S +L ++GAPR RH G V + G +R Q L+G Q+G+YFGS
Sbjct: 251 GYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSA 310
Query: 490 LCPLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQPEPPQDARF 549
+ D + DG D LLV AP + + + G +YV++ + +L P + F
Sbjct: 311 IALADLNNDGWQD-LLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSGSAF 369
Query: 550 GFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAASMP-HAL 608
G ++ ++ D+NQDGF D+AVGAP E G +Y+YH + G+ P Q I + L
Sbjct: 370 GLSVASIGDINQDGFQDIAVGAPFEG--LGKVYIYHSSSKGLLRQPQQVIHGEKLGLPGL 427
Query: 609 SYFGRSVDGRLDLDGDDLVDVAVGA-QGAAILLSSRPIVHLTPSLEVTPQAISVVQRDCR 667
+ FG S+ G++D+D + D+ VG+ +LL +RP++++ + P+ + C
Sbjct: 428 ATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHK-TLVPRPAVLDPALCT 486
Query: 668 RRGQEAVCLTAALCFQVT-SRTPGRWDHQFYMRFTASLDEWTAGARAAFDGSGQRLSPRR 726
C+ LCF S + + +T D R F GS +
Sbjct: 487 ATS----CVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVF--H 540
Query: 727 LRLSVGNVTCEQLHFHVLDT-SDYLRPVALTVTFALD-----------NTTKPGPVLNEG 774
S+ + C++L ++D D LRP+ +++ ++L + P+LN+
Sbjct: 541 GFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQA 600
Query: 775 SPTSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRK-APFVVRGGRRKVLVSTTLENR 833
V F K+CGPDN+C ++L ++ +K + RK+L+S + N
Sbjct: 601 QALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNT 660
Query: 834 K------ENAYNTSLSLIFSRNLHLASLTPQRESPIKVECAAPSAHARLCSVGHPVFQTG 887
+ E+A+ L+L+ L L+S+ P A + C +G+P F+
Sbjct: 661 RTSERSGEDAHEALLTLVVPPALLLSSVRPPG--------ACQANETIFCELGNP-FKRN 711
Query: 888 AKVTFLLEFEFSCSSLLSQ-VFVKLTASSDSLERN------GTLQDNTAQTS 932
++ L+ FE +L ++ + V+L S+ S + N L D T QTS
Sbjct: 712 QRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQDNLWPMILTLLVDYTLQTS 763
Score = 44.7 bits (104), Expect = 5e-04
Identities = 23/54 (42%), Positives = 34/54 (62%), Gaps = 2/54 (3%)
Query: 1112 EVVQTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFF--AHKKIPEEEKREE 1163
E+V+ P I LW+++ +V GLLLL L++ LWK GFF A + E KR++
Sbjct: 981 ELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRARTRALYEAKRQK 1034
>gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]
Length = 1066
Score = 179 bits (453), Expect = 2e-44
Identities = 158/592 (26%), Positives = 268/592 (45%), Gaps = 55/592 (9%)
Query: 372 MSQIGFSTHRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEFPPALQNHAAYL 431
M Q+G S ++ + FG GAY+W G+ ++ + E L Y+
Sbjct: 196 MCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKDPEDQGNL-----YI 250
Query: 432 GYS--VSSMLLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSLQGEQIGSYFGSE 489
GY+ V S +L ++GAPR RH G V + G +R Q L+G Q+G+YFGS
Sbjct: 251 GYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSA 310
Query: 490 LCPLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQPEPPQDARF 549
+ D + DG D LLV AP + + + G +YV++ + +L P + F
Sbjct: 311 IALADLNNDGWQD-LLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSGSAF 369
Query: 550 GFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAASMP-HAL 608
G ++ ++ D+NQDGF D+AVGAP E G +Y+YH + G+ P Q I + L
Sbjct: 370 GLSVASIGDINQDGFQDIAVGAPFEG--LGKVYIYHSSSKGLLRQPQQVIHGEKLGLPGL 427
Query: 609 SYFGRSVDGRLDLDGDDLVDVAVGA-QGAAILLSSRPIVHLTPSLEVTPQAISVVQRDCR 667
+ FG S+ G++D+D + D+ VG+ +LL +RP++++ + P+ + C
Sbjct: 428 ATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHK-TLVPRPAVLDPALCT 486
Query: 668 RRGQEAVCLTAALCFQVT-SRTPGRWDHQFYMRFTASLDEWTAGARAAFDGSGQRLSPRR 726
C+ LCF S + + +T D R F GS +
Sbjct: 487 ATS----CVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVF--H 540
Query: 727 LRLSVGNVTCEQLHFHVLDT-SDYLRPVALTVTFALD-----------NTTKPGPVLNEG 774
S+ + C++L ++D D LRP+ +++ ++L + P+LN+
Sbjct: 541 GFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQA 600
Query: 775 SPTSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRK-APFVVRGGRRKVLVSTTLENR 833
V F K+CGPDN+C ++L ++ +K + RK+L+S + N
Sbjct: 601 QALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNT 660
Query: 834 K------ENAYNTSLSLIFSRNLHLASLTPQRESPIKVECAAPSAHARLCSVGHPVFQTG 887
+ E+A+ L+L+ L L+S+ P A + C +G+P F+
Sbjct: 661 RTSERSGEDAHEALLTLVVPPALLLSSVRPPG--------ACQANETIFCELGNP-FKRN 711
Query: 888 AKVTFLLEFEFSCSSLLSQ-VFVKLTASSDSLERN------GTLQDNTAQTS 932
++ L+ FE +L ++ + V+L S+ S + N L D T QTS
Sbjct: 712 QRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQDNLWPMILTLLVDYTLQTS 763
Score = 40.8 bits (94), Expect = 0.008
Identities = 18/39 (46%), Positives = 26/39 (66%)
Query: 1112 EVVQTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFF 1150
E+V+ P I LW+++ +V GLLLL L++ LWK FF
Sbjct: 981 ELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCDFF 1019
>gi|49170034 integrin, alpha 8 [Homo sapiens]
Length = 1063
Score = 173 bits (438), Expect = 1e-42
Identities = 211/883 (23%), Positives = 369/883 (41%), Gaps = 102/883 (11%)
Query: 364 NESSFGLEMSQIGFSTHRLKDG-ILFGMVGAYDWGGSVLWLEGGHRL-------FPPRMA 415
N G Q GFS K+G ++ G G++ W G V+ + ++A
Sbjct: 191 NADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLA 250
Query: 416 LEDEFPPALQNHA-AYLGYSVSSMLLRG-GRRLFLSGAPRFRHRGKVIAFQLKKDGAVRV 473
E + A ++ +YLGYSV++ G ++ ++G PR ++ D +
Sbjct: 251 GEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSIINSTD--MTF 308
Query: 474 AQSLQGEQIGSYFGSELCPLDTDRDGTTDVLLVAAPMFLGPQ----NKETGRVYVYLVGQ 529
Q+ GEQ+ SYFG + D + DG DVL V AP+F+ + +E G++Y+YL
Sbjct: 309 IQNFTGEQMASYFGYTVVVSDVNSDGLDDVL-VGAPLFMEREFESNPREVGQIYLYLQ-V 366
Query: 530 QSLLTLQGTLQPEPPQDARFGFAMGALPDLNQDGFADVAVGAPLEDGHQ-GALYLYHGTQ 588
SLL + RFG AM L DLNQDG+ D+A+G P Q G + +Y+G +
Sbjct: 367 SSLLFRDPQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNK 426
Query: 589 SGVRPHPAQRIAAASMPHAL-SYFGRSVDGRLDLDGDDLVDVAVGA--QGAAILLSSRPI 645
G+ P+Q + HA+ S FG ++ G D+D +D D+ VGA G + +RP+
Sbjct: 427 DGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPV 486
Query: 646 VHLTPSLEVTPQAISVVQRDCRRRGQ--EAVCLTAALCFQVTSRTPGRWDHQFYMRFTAS 703
V + L + P I++ + C+ A C + +C VT ++ S
Sbjct: 487 VTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIANTIVLMAEVQLDS 546
Query: 704 LDEWTAGARAAF--DGSGQRLSPRRLRLSVGNVTCEQLHFHVLDTSDY---LRPVALTVT 758
L + A R F + R+ P ++ + C+ ++ D +++ L P+ +++
Sbjct: 547 LKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSH-QCQDFIVYLRDETEFRDKLSPINISLN 605
Query: 759 FALDNTT-KPG----PVLNEGSPTSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKA 813
++LD +T K G P+LN + + DCG DN CV DL L D
Sbjct: 606 YSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPDKHQ---- 661
Query: 814 PFVVRGGRRKVLVSTTLENRKENAYNTSLSLIFSRNLHLASLTPQRESPIKVECAAPSAH 873
V+ G +++ N E AY L ++ + + + C +
Sbjct: 662 --VIIGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMEN 719
Query: 874 AR---LCSVGHPVFQTGAKVTFLLEF-----EFSCSSLLSQVFVKLTASSDSLERNGTLQ 925
+C +G+P+ +G + L F E + S+ + ++ + + +LQ
Sbjct: 720 VTRMVVCDLGNPMV-SGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSLQ 778
Query: 926 DNTAQTSAY----IQYEPHLLFSSESTLHRYEVHPYGTLPVGPGPEFKTTLRVQNLGCYV 981
N + + + P ++ +H +E GP + + N+G
Sbjct: 779 INITAVAQVEIRGVSHPPQIVL----PIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPST 834
Query: 982 VSGLIISALLPAVAHGGNYFLSLSQVIT-------NNASCIVQNLTEPPGPPVHPE---- 1030
+S I+ P A + L + + T N + Q++ P PE
Sbjct: 835 ISDTILEVGWPFSAR-DEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAF 893
Query: 1031 ----ELQHTNR-----------------LNGSNTQCQVVRCHLGQLAKGTEVSVGLLR-- 1067
+ H R LN +N +C + C +G+L +G E +V +R
Sbjct: 894 LRNSTIPHLVRKRDVHVVEFHRQSPAKILNCTNIECLQISCAVGRL-EGGESAVLKVRSR 952
Query: 1068 -LVHNEFFRRAKFKSLTVVSTFELG----TEEGSVLQLTEAS-RWSESLLEVVQTRPILI 1121
H R+ +L + +FE+ T++ + +L E S S++ I
Sbjct: 953 LWAHTFLQRKNDPYALASLVSFEVKKMPYTDQPA--KLPEGSIAIKTSVIWATPNVSFSI 1010
Query: 1122 SLWILIGSVLGGLLLLALLVFCLWKLGFFAHKKIPEEEKREEK 1164
LW++I ++L GLL+LA+L LWK GFF + P+E+ + +
Sbjct: 1011 PLWVIILAILLGLLVLAILTLALWKCGFFDRARPPQEDMTDRE 1053
Score = 37.7 bits (86), Expect = 0.064
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 11 LPLVFLTGLCSPFNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQ-RWMLVGAP---WDGPS 66
L ++ + C FNLD ++ GP + FGY+V H+ + +LVGAP P
Sbjct: 27 LGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYAVDFHIPDARTASVLVGAPKANTSQPD 86
Query: 67 GDRRGDVYRCPVGGAHNAPC 86
G VY CP +A C
Sbjct: 87 IVEGGAVYYCPWPAEGSAQC 106
>gi|56237029 integrin alpha 5 precursor [Homo sapiens]
Length = 1049
Score = 166 bits (419), Expect = 2e-40
Identities = 214/868 (24%), Positives = 347/868 (39%), Gaps = 138/868 (15%)
Query: 374 QIGFSTHRLKDG-ILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEFPPALQNHA---- 428
Q GFS K G ++ G G+Y W G +L E +P L N
Sbjct: 206 QGGFSAEFTKTGRVVLGGPGSYFWQGQILSAT-------QEQIAESYYPEYLINLVQGQL 258
Query: 429 -----------AYLGYSVSSMLLRGG-RRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQS 476
+YLGYSV+ G F++G P+ + D +R +
Sbjct: 259 QTRQASSIYDDSYLGYSVAVGEFSGDDTEDFVAGVPKGNLTYGYVTILNGSD--IRSLYN 316
Query: 477 LQGEQIGSYFGSELCPLDTDRDGTTDVLLVAAPMFLGP----QNKETGRVYVYL-----V 527
GEQ+ SYFG + D + DG D LLV AP+ + + +E GRVYVYL +
Sbjct: 317 FSGEQMASYFGYAVAATDVNGDGLDD-LLVGAPLLMDRTPDGRPQEVGRVYVYLQHPAGI 375
Query: 528 GQQSLLTLQGTLQPEPPQDARFGFAMGALPDLNQDGFADVAVGAPL-EDGHQGALYLYHG 586
LTL G + RFG ++ L DL+QDG+ DVA+GAP + QG ++++ G
Sbjct: 376 EPTPTLTLTGH-----DEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGETQQGVVFVFPG 430
Query: 587 TQSGVRPHPAQRIAAA-SMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGA--AILLSSR 643
G+ P+Q + + H +FG ++ G DLDG+ D+ VG+ G A++ R
Sbjct: 431 GPGGLGSKPSQVLQPLWAASHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYRGR 490
Query: 644 PIVHLTPSLEVTPQAISVVQRDCRRRGQEAVCLTAALCFQVTSRTPGRWDHQFYMRFTAS 703
PIV + SL + P + +R C G C+ + C + + + FT
Sbjct: 491 PIVSASASLTIFPAMFNPEERSCSLEGNPVACINLSFCLNASGKHVAD-----SIGFTVE 545
Query: 704 LD-EWT----AGARAAFDGSGQRLSPRRLRLSVG-NVTCEQLHFHVLDTSDY---LRPVA 754
L +W RA F S Q + L + G C ++ ++ + S++ L P+
Sbjct: 546 LQLDWQKQKGGVRRALFLASRQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPIH 605
Query: 755 LTVTFALD-----NTTKPGPVLNEGSPTSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRG 809
+ + F+LD ++ P L+ S + I+ DCG DN CV DL L+V
Sbjct: 606 IALNFSLDPQAPVDSHGLRPALHYQSKSRIEDKAQILLDCGEDNICVPDLQLEV------ 659
Query: 810 SRKAPFVVRGGRRKVLVSTTLENRKE-NAYNTSLSLIFSRNLHLASLTPQRESPIKVEC- 867
+ V G + + ++ +N E AY L + + L + + C
Sbjct: 660 FGEQNHVYLGDKNALNLTFHAQNVGEGGAYEAELRVTAPPEAEYSGLVRHPGNFSSLSCD 719
Query: 868 --AAPSAHARLCSVGHPVFQTGA----------------KVTFLLEFEFSCSSLLSQVFV 909
A + +C +G+P+ + GA K T +F+ +L +
Sbjct: 720 YFAVNQSRLLVCDLGNPM-KAGASLWGGLRFTVPHLRDTKKTIQFDFQILSKNLNN---- 774
Query: 910 KLTASSDSLERNGTLQDNTAQTSAYIQYEPHLLFSSESTLHRYEVHPYGTLPVGPGPEFK 969
+ SD + +++ T + +LF R + L GP
Sbjct: 775 ---SQSDVVSFRLSVEAQAQVTLNGVSKPEAVLFPVSDWHPRDQPQKEEDL----GPAVH 827
Query: 970 TTLRVQNLGCYVVSGLIISALLPAVAHGGNYFLSLSQVITNNASCIVQNLTEPPGPPVHP 1029
+ N G +S ++ P A G L +++V +C + P G + P
Sbjct: 828 HVYELINQGPSSISQGVLELSCPQ-ALEGQQLLYVTRV--TGLNCTTNHPINPKGLELDP 884
Query: 1030 E-ELQHTNR---------------LNGSNTQCQVVRCHLGQLAKGTEVSVGL-LRLVHNE 1072
E L H + L +C +RC LG L + S+ L R+
Sbjct: 885 EGSLHHQQKREAPSRSSASSGPQILKCPEAECFRLRCELGPLHQQESQSLQLHFRVWAKT 944
Query: 1073 FFRR----------AKFKSLTVVSTFELGTEEGSVLQLTEASRWSESLLEVVQTRPILIS 1122
F +R A +K+L + Q+ A +W+++ +
Sbjct: 945 FLQREHQPFSLQCEAVYKALKMPYRILPRQLPQKERQVATAVQWTKA------EGSYGVP 998
Query: 1123 LWILIGSVLGGLLLLALLVFCLWKLGFF 1150
LWI+I ++L GLLLL LL++ L+KLGFF
Sbjct: 999 LWIIILAILFGLLLLGLLIYILYKLGFF 1026
Score = 37.0 bits (84), Expect = 0.11
Identities = 25/63 (39%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Query: 23 FNLDEHHPRLFPGPPEAEFGYSV-LQHVGGGQRWMLVGAP---WDGPSGDRRGDVYRCPV 78
FNLD P + GPP + FG+SV G +LVGAP P + G VY CP
Sbjct: 42 FNLDAEAPAVLSGPPGSFFGFSVEFYRPGTDGVSVLVGAPKANTSQPGVLQGGAVYLCPW 101
Query: 79 GGA 81
G +
Sbjct: 102 GAS 104
>gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]
Length = 1039
Score = 156 bits (395), Expect = 1e-37
Identities = 201/769 (26%), Positives = 320/769 (41%), Gaps = 101/769 (13%)
Query: 469 GAVRVAQS-------LQGEQIGSYFGSELCPLDTDRDGTTDVLLVAAPMFLGPQNK---- 517
GAV + S L+GEQ+ SYFG + D + DG D LLV AP+++ +
Sbjct: 296 GAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHD-LLVGAPLYMESRADRKLA 354
Query: 518 ETGRVYVYL-------VGQQSLLTLQGTLQPEPPQDARFGFAMGALPDLNQDGFADVAVG 570
E GRVY++L +G SLL L GT RFG A+ L DL++DG+ D+AV
Sbjct: 355 EVGRVYLFLQPRGPHALGAPSLL-LTGT-----QLYGRFGSAIAPLGDLDRDGYNDIAVA 408
Query: 571 APL-EDGHQGALYLYHGTQSGVRPHPAQRIAAASMPHALSYFGRSVDGRLDLDGDDLVDV 629
AP +G + ++ G G+R P+Q + + P S FG S+ G +D+D + D+
Sbjct: 409 APYGGPSGRGQVLVFLGQSEGLRSRPSQ-VLDSPFPTG-SAFGFSLRGAVDIDDNGYPDL 466
Query: 630 AVGAQGA--AILLSSRPIVHLTPSLEVTPQAISVVQRDCRRRGQEAV-CLTAALCFQVTS 686
VGA GA + ++P+V + L V V+ + + V C +C T
Sbjct: 467 IVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATG 526
Query: 687 RTPGRWDHQFYMRFTASLDEW--TAGARAAFDGSGQRLSPRRLRLSVG---NVTCEQLHF 741
+ + LD G R GS Q + L L +G + C
Sbjct: 527 H---NIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQ--AGTTLNLDLGGKHSPICHTTMA 581
Query: 742 HVLDTSDY---LRPVALTVTFALDNT---TKPGPVLNEGSPTSIQKLVPFSKDCGPDNEC 795
+ D +D+ L P+ L++ +L T P VL+ T +Q+ DCG D+ C
Sbjct: 582 FLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLH--GDTHVQEQTRIVLDCGEDDVC 639
Query: 796 VTDLVLQVNMDIRGSRKAPFVVRGGRRKVLVSTTLENRKENAYNTSLSLIFSRNLHLASL 855
V LQ+ + GS P +V G + + N E AY L++ + H
Sbjct: 640 VPQ--LQLTASVTGS---PLLV-GADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRA 693
Query: 856 TPQRESPIKVECAAPSAHAR---LCSVGHPVFQTG----AKVTFLLEFEFSCSSLLSQVF 908
E ++ C + LC +G+P+ + A + + E + S+ Q+
Sbjct: 694 LSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQ 753
Query: 909 VKLTASSDSLERNGTLQDNTAQTSAYIQYEPHLLFSSESTLHRYEVHPYGTLPVGPGPEF 968
++ + +S + L D + A ++ + +S +L GP+
Sbjct: 754 IR-SKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLD-SWGPKV 811
Query: 969 KTTLRVQNLGCYVVSGLIISALLPAVAHGGNYFLSLSQVITNNASCIVQNLTEP------ 1022
+ T + N G V+GL +S LP + + L C Q P
Sbjct: 812 EHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWG 871
Query: 1023 ---PGP-PVH------------------PEELQHTNRLNGSNTQCQVVRCHLGQLAKGTE 1060
P P P+H P LQ ++ + C VV+C L ++A+G
Sbjct: 872 LPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQR 931
Query: 1061 VSVGLLRLVHNEFFRRAKFKSLTVVS--TFELGTEEGSVLQLT----EASRWSESLLEVV 1114
V +L + + + S F + + +V L+ EA W++ LL +
Sbjct: 932 AMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQ-LLRAL 990
Query: 1115 QTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFFAHKKIPEEEKREE 1163
+ R I I W+L+G VLGGLLLL +LV +WK+GFF + P EE EE
Sbjct: 991 EERAIPI-WWVLVG-VLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEE 1037
Score = 35.0 bits (79), Expect = 0.42
Identities = 24/72 (33%), Positives = 37/72 (51%), Gaps = 7/72 (9%)
Query: 13 LVFLTGLCSP-----FNLDEHHPRLFPGPPEAEFGYSVLQHVGG-GQRWMLVGAPWD-GP 65
++ L G C+ NLD + GP ++FG+S+ H G+ ++VGAP GP
Sbjct: 17 VLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGP 76
Query: 66 SGDRRGDVYRCP 77
S + G V+ CP
Sbjct: 77 SQEETGGVFLCP 88
>gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]
Length = 1002
Score = 149 bits (377), Expect = 1e-35
Identities = 155/553 (28%), Positives = 253/553 (45%), Gaps = 54/553 (9%)
Query: 369 GLEMSQIGFSTHRLK-DGILFGMVGAYDWGGSVLW---LEGGHRLFPPRMALEDEFPPAL 424
G Q GFS K D +L G G++ W G ++ E + P +++ A
Sbjct: 135 GQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLAT 194
Query: 425 QNHAA-----YLGYSVSSMLLRG-GRRLFLSGAPRF-RHRGKVIAFQLKKDGAVRVAQSL 477
+ A YLGYSV+ G G F+SG PR R G V + K ++ +
Sbjct: 195 RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSL---YNF 251
Query: 478 QGEQIGSYFGSELCPLDTDRDGTTDVLLVAAPMFL--GPQNK--ETGRVYVYLVGQQSLL 533
GEQ+ +YFG + D + D DV + AP+F+ G K E G+V V L Q++
Sbjct: 252 TGEQMAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSL--QRASG 308
Query: 534 TLQGTLQPEPPQDARFGFAMGALPDLNQDGFADVAVGAPL-EDGHQGALYLYHGTQSGVR 592
Q T ARFG A+ L DL+QDGF D+A+ AP + +G +Y+++G +G+
Sbjct: 309 DFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLN 368
Query: 593 PHPAQRI----AAASMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGA--AILLSSRPIV 646
P+Q + AA SMP + FG S+ G D+D + D+ VGA G AIL +RP++
Sbjct: 369 AVPSQILEGQWAARSMPPS---FGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVI 425
Query: 647 HLTPSLEVTPQAISVVQRDCRRRGQ--EAVCLTAALCFQVTSR--TPGRWDHQFYMRFTA 702
+ LEV P ++ + C G + C C + + P + + Q +
Sbjct: 426 TVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVEL-LLD 484
Query: 703 SLDEWTAGARAAFDGSGQRLSPRRLRLSVGN-VTCEQLHFHVLDTSDY---LRPVALTVT 758
L + A RA F S + + +S G + CE+L ++ D S++ L P+ + +
Sbjct: 485 KLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFME 544
Query: 759 FALD-----NTTKPGPVLNEGSPTSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKA 813
+ LD +TT P+LN+ +P +I + DCG DN C L + V+ D +K
Sbjct: 545 YRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSD----QKK 600
Query: 814 PFVVRGGRRKVLVSTTLENRKENAYNTSLSLIFSRNLHLASLTPQRESPIKVECAAPSAH 873
++ G + + +N+ E AY L + + E+ ++ CA + +
Sbjct: 601 IYI--GDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTEN 658
Query: 874 AR---LCSVGHPV 883
+C +G+P+
Sbjct: 659 QTRQVVCDLGNPM 671
Score = 65.1 bits (157), Expect = 4e-10
Identities = 36/130 (27%), Positives = 70/130 (53%), Gaps = 7/130 (5%)
Query: 1044 QCQVVRCHLGQLAKGTEVSVGLLRLVHNEFFRRAK-------FKSLTVVSTFELGTEEGS 1096
QC + C +G+L +G + + L+ E F + KS + E +
Sbjct: 862 QCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLP 921
Query: 1097 VLQLTEASRWSESLLEVVQTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFFAHKKIP 1156
+ +T ++ + ++ +Q P+ + +W++I +VL GLLLLA+LVF ++++GFF + P
Sbjct: 922 IEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPP 981
Query: 1157 EEEKREEKLE 1166
+EE+ E+L+
Sbjct: 982 QEEQEREQLQ 991
>gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]
Length = 1048
Score = 149 bits (377), Expect = 1e-35
Identities = 155/553 (28%), Positives = 253/553 (45%), Gaps = 54/553 (9%)
Query: 369 GLEMSQIGFSTHRLK-DGILFGMVGAYDWGGSVLW---LEGGHRLFPPRMALEDEFPPAL 424
G Q GFS K D +L G G++ W G ++ E + P +++ A
Sbjct: 181 GQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLAT 240
Query: 425 QNHAA-----YLGYSVSSMLLRG-GRRLFLSGAPRF-RHRGKVIAFQLKKDGAVRVAQSL 477
+ A YLGYSV+ G G F+SG PR R G V + K ++ +
Sbjct: 241 RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSL---YNF 297
Query: 478 QGEQIGSYFGSELCPLDTDRDGTTDVLLVAAPMFL--GPQNK--ETGRVYVYLVGQQSLL 533
GEQ+ +YFG + D + D DV + AP+F+ G K E G+V V L Q++
Sbjct: 298 TGEQMAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSL--QRASG 354
Query: 534 TLQGTLQPEPPQDARFGFAMGALPDLNQDGFADVAVGAPL-EDGHQGALYLYHGTQSGVR 592
Q T ARFG A+ L DL+QDGF D+A+ AP + +G +Y+++G +G+
Sbjct: 355 DFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLN 414
Query: 593 PHPAQRI----AAASMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGA--AILLSSRPIV 646
P+Q + AA SMP + FG S+ G D+D + D+ VGA G AIL +RP++
Sbjct: 415 AVPSQILEGQWAARSMPPS---FGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVI 471
Query: 647 HLTPSLEVTPQAISVVQRDCRRRGQ--EAVCLTAALCFQVTSR--TPGRWDHQFYMRFTA 702
+ LEV P ++ + C G + C C + + P + + Q +
Sbjct: 472 TVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVEL-LLD 530
Query: 703 SLDEWTAGARAAFDGSGQRLSPRRLRLSVGN-VTCEQLHFHVLDTSDY---LRPVALTVT 758
L + A RA F S + + +S G + CE+L ++ D S++ L P+ + +
Sbjct: 531 KLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFME 590
Query: 759 FALD-----NTTKPGPVLNEGSPTSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKA 813
+ LD +TT P+LN+ +P +I + DCG DN C L + V+ D +K
Sbjct: 591 YRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSD----QKK 646
Query: 814 PFVVRGGRRKVLVSTTLENRKENAYNTSLSLIFSRNLHLASLTPQRESPIKVECAAPSAH 873
++ G + + +N+ E AY L + + E+ ++ CA + +
Sbjct: 647 IYI--GDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTEN 704
Query: 874 AR---LCSVGHPV 883
+C +G+P+
Sbjct: 705 QTRQVVCDLGNPM 717
Score = 65.1 bits (157), Expect = 4e-10
Identities = 36/130 (27%), Positives = 70/130 (53%), Gaps = 7/130 (5%)
Query: 1044 QCQVVRCHLGQLAKGTEVSVGLLRLVHNEFFRRAK-------FKSLTVVSTFELGTEEGS 1096
QC + C +G+L +G + + L+ E F + KS + E +
Sbjct: 908 QCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLP 967
Query: 1097 VLQLTEASRWSESLLEVVQTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFFAHKKIP 1156
+ +T ++ + ++ +Q P+ + +W++I +VL GLLLLA+LVF ++++GFF + P
Sbjct: 968 IEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPP 1027
Query: 1157 EEEKREEKLE 1166
+EE+ E+L+
Sbjct: 1028 QEEQEREQLQ 1037
Score = 35.0 bits (79), Expect = 0.42
Identities = 34/127 (26%), Positives = 46/127 (36%), Gaps = 9/127 (7%)
Query: 11 LPLVF---LTGLCSPFNLDEHHPRLFPGPPEAEFGYSVLQHV--GGGQRWMLVGAP---W 62
LPL+ L LC FNLD P + GP + FG++V V + ++LVGAP
Sbjct: 16 LPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANT 75
Query: 63 DGPSGDRRGDVYRCPVGGAHNA-PCAKGHLGDYQLGNSSHPAVNMHLGMSLLETDGDGGF 121
P G V +C P G+ H
Sbjct: 76 TQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKI 135
Query: 122 MACAPLW 128
+ACAPL+
Sbjct: 136 LACAPLY 142
>gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]
Length = 1012
Score = 149 bits (375), Expect = 2e-35
Identities = 139/484 (28%), Positives = 228/484 (47%), Gaps = 45/484 (9%)
Query: 429 AYLGYSVSSMLLRG-GRRLFLSGAPRF-RHRGKVIAFQLKKDGAVRVAQSLQGEQIGSYF 486
+YLGYSV+ G G F+SG PR R G V + K ++ + GEQ+ +YF
Sbjct: 214 SYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSL---YNFTGEQMAAYF 270
Query: 487 GSELCPLDTDRDGTTDVLLVAAPMFL--GPQNK--ETGRVYVYLVGQQSLLTLQGTLQPE 542
G + D + D DV + AP+F+ G K E G+V V L Q++ Q T
Sbjct: 271 GFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSL--QRASGDFQTTKLNG 327
Query: 543 PPQDARFGFAMGALPDLNQDGFADVAVGAPL-EDGHQGALYLYHGTQSGVRPHPAQRI-- 599
ARFG A+ L DL+QDGF D+A+ AP + +G +Y+++G +G+ P+Q +
Sbjct: 328 FEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEG 387
Query: 600 --AAASMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGA--AILLSSRPIVHLTPSLEVT 655
AA SMP + FG S+ G D+D + D+ VGA G AIL +RP++ + LEV
Sbjct: 388 QWAARSMPPS---FGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY 444
Query: 656 PQAISVVQRDCRRRGQ--EAVCLTAALCFQVTSR--TPGRWDHQFYMRFTASLDEWTAGA 711
P ++ + C G + C C + + P + + Q + L + A
Sbjct: 445 PSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVEL-LLDKLKQKGAIR 503
Query: 712 RAAFDGSGQRLSPRRLRLSVGN-VTCEQLHFHVLDTSDY---LRPVALTVTFALD----- 762
RA F S + + +S G + CE+L ++ D S++ L P+ + + + LD
Sbjct: 504 RALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAA 563
Query: 763 NTTKPGPVLNEGSPTSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKAPFVVRGGRR 822
+TT P+LN+ +P +I + DCG DN C L + V+ D +K ++ G
Sbjct: 564 DTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSD----QKKIYI--GDDN 617
Query: 823 KVLVSTTLENRKENAYNTSLSLIFSRNLHLASLTPQRESPIKVECAAPSAHAR---LCSV 879
+ + +N+ E AY L + + E+ ++ CA + + +C +
Sbjct: 618 PLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDL 677
Query: 880 GHPV 883
G+P+
Sbjct: 678 GNPM 681
Score = 65.1 bits (157), Expect = 4e-10
Identities = 36/130 (27%), Positives = 70/130 (53%), Gaps = 7/130 (5%)
Query: 1044 QCQVVRCHLGQLAKGTEVSVGLLRLVHNEFFRRAK-------FKSLTVVSTFELGTEEGS 1096
QC + C +G+L +G + + L+ E F + KS + E +
Sbjct: 872 QCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLP 931
Query: 1097 VLQLTEASRWSESLLEVVQTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFFAHKKIP 1156
+ +T ++ + ++ +Q P+ + +W++I +VL GLLLLA+LVF ++++GFF + P
Sbjct: 932 IEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPP 991
Query: 1157 EEEKREEKLE 1166
+EE+ E+L+
Sbjct: 992 QEEQEREQLQ 1001
Score = 35.0 bits (79), Expect = 0.42
Identities = 34/127 (26%), Positives = 46/127 (36%), Gaps = 9/127 (7%)
Query: 11 LPLVF---LTGLCSPFNLDEHHPRLFPGPPEAEFGYSVLQHV--GGGQRWMLVGAP---W 62
LPL+ L LC FNLD P + GP + FG++V V + ++LVGAP
Sbjct: 16 LPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANT 75
Query: 63 DGPSGDRRGDVYRCPVGGAHNA-PCAKGHLGDYQLGNSSHPAVNMHLGMSLLETDGDGGF 121
P G V +C P G+ H
Sbjct: 76 TQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKI 135
Query: 122 MACAPLW 128
+ACAPL+
Sbjct: 136 LACAPLY 142
>gi|93141049 collagen, type XII, alpha 1 short isoform precursor
[Homo sapiens]
Length = 1899
Score = 90.1 bits (222), Expect = 1e-17
Identities = 66/217 (30%), Positives = 105/217 (48%), Gaps = 18/217 (8%)
Query: 167 DVVIVLDGSNSI--YPWSEVQTFLRRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGDFRT 224
D+V+++DGS SI + V++F+ R+V I P+++Q+ L QY P EW L R
Sbjct: 35 DIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRD 94
Query: 225 KEEVVRAAKNLSRREGRETKTAQAIMVACTEGFSQSHGGRPEAARLLVVVTDGESHDGEE 284
K+ +++A NL + G T T A+ + F G RP A ++ V++TDG+S D E
Sbjct: 95 KKSLLQAVANLPYK-GGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVE 153
Query: 285 LPAALKACEAGRVTRYGIAVLGHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDEAALT 344
P+ E + GI E++ IA+DPD+ +NV D +L+
Sbjct: 154 APSKKLKDEGVELFAIGIKNADEV------------ELKMIATDPDDTHAYNVADFESLS 201
Query: 345 DIVDALGDRIFGLEGSHAENESSFGLEMSQIGFSTHR 381
IVD L + + E+ L +S+ THR
Sbjct: 202 RIVDDLTINLCNSVKGPGDLEAPSNLVISE---RTHR 235
Score = 62.8 bits (151), Expect = 2e-09
Identities = 63/205 (30%), Positives = 91/205 (44%), Gaps = 19/205 (9%)
Query: 151 PQGSLAPTAQRCP-TYMDVVIVLDGSNSIYP--WSEVQTFLRRLVGKLF-IDPEQIQVGL 206
P ++ P C D+V + D S SI +++V F+ VG I P IQV
Sbjct: 1142 PPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSF 1201
Query: 207 VQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREGRETKTAQAIMVACTEGFSQSHGGRPE 266
VQY + E+ L + K + A +N+ R G T+T +A+ + + G R
Sbjct: 1202 VQYSDEVKSEFKLNTYNDKALALGALQNI-RYRGGNTRTGKALTFIKEKVLTWESGMRKN 1260
Query: 267 AARLLVVVTDGESHDGEELPAALKACEAG-RVTRYGIAVLGHYLRRQRDPSSFLREIRTI 325
++LVVVTDG S D E AAL ++G V G+A + + E+ I
Sbjct: 1261 VPKVLVVVTDGRSQD-EVKKAALVIQQSGFSVFVVGVADVDY------------NELANI 1307
Query: 326 ASDPDERFFFNVTDEAALTDIVDAL 350
AS P ER F V D + I D L
Sbjct: 1308 ASKPSERHVFIVDDFESFEKIEDNL 1332
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
sapiens]
Length = 3063
Score = 90.1 bits (222), Expect = 1e-17
Identities = 66/217 (30%), Positives = 105/217 (48%), Gaps = 18/217 (8%)
Query: 167 DVVIVLDGSNSI--YPWSEVQTFLRRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGDFRT 224
D+V+++DGS SI + V++F+ R+V I P+++Q+ L QY P EW L R
Sbjct: 1199 DIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRD 1258
Query: 225 KEEVVRAAKNLSRREGRETKTAQAIMVACTEGFSQSHGGRPEAARLLVVVTDGESHDGEE 284
K+ +++A NL + G T T A+ + F G RP A ++ V++TDG+S D E
Sbjct: 1259 KKSLLQAVANLPYK-GGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVE 1317
Query: 285 LPAALKACEAGRVTRYGIAVLGHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDEAALT 344
P+ E + GI E++ IA+DPD+ +NV D +L+
Sbjct: 1318 APSKKLKDEGVELFAIGIKNADEV------------ELKMIATDPDDTHAYNVADFESLS 1365
Query: 345 DIVDALGDRIFGLEGSHAENESSFGLEMSQIGFSTHR 381
IVD L + + E+ L +S+ THR
Sbjct: 1366 RIVDDLTINLCNSVKGPGDLEAPSNLVISE---RTHR 1399
Score = 72.8 bits (177), Expect = 2e-12
Identities = 53/191 (27%), Positives = 94/191 (49%), Gaps = 17/191 (8%)
Query: 160 QRCPT--YMDVVIVLDGSNSI--YPWSEVQTFLRRLVGKLFIDPEQIQVGLVQYGESPVH 215
Q+C + D+V ++DGS S+ + + F+ LV I E+ +VG+VQY
Sbjct: 131 QKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRT 190
Query: 216 EWSLGDFRTKEEVVRAAKNLSRREGRETKTAQAIMVACTEGFSQSHGGRPEAARLLVVVT 275
E++L + ++E++ A K + + G T T AI F++S G R ++ +++T
Sbjct: 191 EFNLNQYYQRDELLAAIKKIPYKGGN-TMTGDAIDYLVKNTFTESAGARVGFPKVAIIIT 249
Query: 276 DGESHDGEELPAALKACEAGRVTRYGIAVLGHYLRRQRDPSSFLREIRTIASDPDERFFF 335
DG+S D E+PA + G+ V ++ ++ +E++ IAS P F
Sbjct: 250 DGKSQDEVEIPAR-------ELRNVGVEVFSLGIK-----AADAKELKQIASTPSLNHVF 297
Query: 336 NVTDEAALTDI 346
NV + A+ DI
Sbjct: 298 NVANFDAIVDI 308
Score = 70.9 bits (172), Expect = 7e-12
Identities = 51/175 (29%), Positives = 79/175 (45%), Gaps = 15/175 (8%)
Query: 167 DVVIVLDGSNSI--YPWSEVQTFLRRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGDFRT 224
D+V ++DGS SI + +V+ FL LV I P ++Q+ LVQY P E++L F
Sbjct: 440 DIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTK 499
Query: 225 KEEVVRAAKNLSRREGRETKTAQAIMVACTEGFSQSHGGRPEAARLLVVVTDGESHDGEE 284
E+++ A R G T T +A+ + F S G R ++++++TDG+S D
Sbjct: 500 VEDIIEAINTFPYR-GGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFR 558
Query: 285 LPAALKACEAGRVTRYGIAVLGHYLRRQRDPSSFLREIRTIASDPDERFFFNVTD 339
PA + G+ + E+ IAS P E F V D
Sbjct: 559 DPAIKLRNSDVEIFAVGV------------KDAVRSELEAIASPPAETHVFTVED 601
Score = 62.8 bits (151), Expect = 2e-09
Identities = 63/205 (30%), Positives = 91/205 (44%), Gaps = 19/205 (9%)
Query: 151 PQGSLAPTAQRCP-TYMDVVIVLDGSNSIYP--WSEVQTFLRRLVGKLF-IDPEQIQVGL 206
P ++ P C D+V + D S SI +++V F+ VG I P IQV
Sbjct: 2306 PPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSF 2365
Query: 207 VQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREGRETKTAQAIMVACTEGFSQSHGGRPE 266
VQY + E+ L + K + A +N+ R G T+T +A+ + + G R
Sbjct: 2366 VQYSDEVKSEFKLNTYNDKALALGALQNI-RYRGGNTRTGKALTFIKEKVLTWESGMRKN 2424
Query: 267 AARLLVVVTDGESHDGEELPAALKACEAG-RVTRYGIAVLGHYLRRQRDPSSFLREIRTI 325
++LVVVTDG S D E AAL ++G V G+A + + E+ I
Sbjct: 2425 VPKVLVVVTDGRSQD-EVKKAALVIQQSGFSVFVVGVADVDY------------NELANI 2471
Query: 326 ASDPDERFFFNVTDEAALTDIVDAL 350
AS P ER F V D + I D L
Sbjct: 2472 ASKPSERHVFIVDDFESFEKIEDNL 2496
>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
Length = 1796
Score = 86.7 bits (213), Expect = 1e-16
Identities = 59/190 (31%), Positives = 98/190 (51%), Gaps = 15/190 (7%)
Query: 163 PTYMDVVIVLDGSNSI--YPWSEVQTFLRRLVGKLFIDPEQIQVGLVQYGESPVHEWSLG 220
P D+VI++DGS SI + + V+ FL LV + E+ ++GL QY P EW L
Sbjct: 154 PAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQYSGDPRIEWHLN 213
Query: 221 DFRTKEEVVRAAKNLSRREGRETKTAQAIMVACTEGFSQSHGGRPEAARLLVVVTDGESH 280
F TK+EV+ A +NL + G T T A+ F G R +++ +++TDG+S
Sbjct: 214 AFSTKDEVIEAVRNLPYK-GGNTLTGLALNYIFENSFKPEAGSRTGVSKIGILITDGKSQ 272
Query: 281 DGEELPAALKACEAGRVTRYGIAVLGHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDE 340
D + +P + E+G V + I V ++ + E++ IAS+PD +NV +
Sbjct: 273 D-DIIPPSRNLRESG-VELFAIGV----------KNADVNELQEIASEPDSTHVYNVAEF 320
Query: 341 AALTDIVDAL 350
+ +V++L
Sbjct: 321 DLMHTVVESL 330
Score = 65.9 bits (159), Expect = 2e-10
Identities = 58/187 (31%), Positives = 90/187 (48%), Gaps = 16/187 (8%)
Query: 167 DVVIVLDGSNSIYP--WSEVQTFLRRLVGKLF-IDPEQIQVGLVQYGESPVHEWSLGDFR 223
D+V ++DGS SI ++++ +FL VG L I + QV +VQ+ + P E+ L ++
Sbjct: 1032 DLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMVQFTDDPRTEFKLNAYK 1091
Query: 224 TKEEVVRAAKNLSRREGRETKTAQAIMVACTEGFSQSHGGRPEAARLLVVVTDGESHDGE 283
TKE ++ A K++S + G TKT +AI F+ G R +++VV+TDG S D
Sbjct: 1092 TKETLLDAIKHISYK-GGNTKTGKAIKYVRDTLFTAESGTRRGIPKVIVVITDGRSQDDV 1150
Query: 284 ELPAALKACEAGRVTRYGIAVLGHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDEAAL 343
K ++ Y I +G + E+ +I S P R F V D A
Sbjct: 1151 N-----KISREMQLDGYSIFAIG-------VADADYSELVSIGSKPSARHVFFVDDFDAF 1198
Query: 344 TDIVDAL 350
I D L
Sbjct: 1199 KKIEDEL 1205
>gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens]
Length = 496
Score = 81.3 bits (199), Expect = 5e-15
Identities = 61/191 (31%), Positives = 95/191 (49%), Gaps = 17/191 (8%)
Query: 167 DVVIVLDGSNSIYP--WSEVQTFLRRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGDFRT 224
D+V ++DGS S+ P + V+ F+ ++V L + + QVGLVQY S E+ LG F T
Sbjct: 275 DLVFLIDGSKSVRPENFELVKKFISQIVDTLDVSDKLAQVGLVQYSSSVRQEFPLGRFHT 334
Query: 225 KEEVVRAAKNLSRREGRETKTAQAIMVACTEGFSQSHGGRPEAARLLVVVTDGESHDGEE 284
K+++ A +N+S E + T T A+ F+ S G RP A ++ +V TDG S D
Sbjct: 335 KKDIKAAVRNMSYME-KGTMTGAALKYLIDNSFTVSSGARPGAQKVGIVFTDGRSQDYIN 393
Query: 285 LPAALKACEAG-RVTRYGIAVLGHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDEAAL 343
AA KA + G ++ G+ ++ E+R IAS+P +F D +
Sbjct: 394 -DAAKKAKDLGFKMFAVGVG------------NAVEDELREIASEPVAEHYFYTADFKTI 440
Query: 344 TDIVDALGDRI 354
I L +I
Sbjct: 441 NQIGKKLQKKI 451
Score = 64.3 bits (155), Expect = 6e-10
Identities = 44/137 (32%), Positives = 74/137 (54%), Gaps = 11/137 (8%)
Query: 150 QPQGSLAPTAQRCPTYMDVVIVLDGSNSIYP--WSEVQTFLRRLVGKLFIDPEQIQVGLV 207
Q +G L T PT D+V V+D S S+ P + +V+ FL +++ L + P +VG+V
Sbjct: 29 QSRGHLCRTR---PT--DLVFVVDSSRSVRPVEFEKVKVFLSQVIESLDVGPNATRVGMV 83
Query: 208 QYGESPVHEWSLGDFRTKEEVVRAAKNLSRREGRETKTAQAIMVACTEGFSQSHGGR--- 264
Y + E+SL +K +++A + + + T T AI A T+ F + GGR
Sbjct: 84 NYASTVKQEFSLRAHVSKAALLQAVRRI-QPLSTGTMTGLAIQFAITKAFGDAEGGRSRS 142
Query: 265 PEAARLLVVVTDGESHD 281
P+ +++++VVTDG D
Sbjct: 143 PDISKVVIVVTDGRPQD 159
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,058,548
Number of Sequences: 37866
Number of extensions: 2328048
Number of successful extensions: 5327
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 4842
Number of HSP's gapped (non-prelim): 175
length of query: 1167
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1054
effective length of database: 13,968,660
effective search space: 14722967640
effective search space used: 14722967640
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.