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Search of human proteins with 38505161
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38505161 tudor domain containing 1 [Homo sapiens]
(1189 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38505161 tudor domain containing 1 [Homo sapiens] 2410 0.0
gi|169163653 PREDICTED: similar to tudor domain containing 1 [Ho... 139 2e-32
gi|169164192 PREDICTED: similar to tudor domain containing 1 [Ho... 139 2e-32
gi|169163210 PREDICTED: similar to tudor domain containing 1 [Ho... 139 2e-32
gi|58197558 tudor domain containing 6 [Homo sapiens] 134 4e-31
gi|94421471 ring finger protein 17 [Homo sapiens] 119 1e-26
gi|112293287 tudor domain containing 7 [Homo sapiens] 109 2e-23
gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 89 2e-17
gi|145312246 tudor and KH domain containing isoform b [Homo sapi... 89 2e-17
gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 89 2e-17
gi|145312256 tudor and KH domain containing isoform a [Homo sapi... 89 2e-17
gi|40255178 tudor domain containing 5 [Homo sapiens] 80 9e-15
gi|77404397 staphylococcal nuclease domain containing 1 [Homo sa... 58 6e-08
gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens] 57 8e-08
gi|170784859 serine/threonine kinase 31 isoform b [Homo sapiens] 57 8e-08
gi|14602443 serine/threonine kinase 31 isoform a [Homo sapiens] 57 8e-08
gi|170784856 serine/threonine kinase 31 isoform b [Homo sapiens] 57 8e-08
gi|166851804 tudor domain containing 9 [Homo sapiens] 55 4e-07
gi|28461129 ankyrin repeat and MYND domain containing 2 [Homo sa... 49 4e-05
gi|188035871 SET and MYND domain containing 2 [Homo sapiens] 46 2e-04
gi|38016945 deformed epidermal autoregulatory factor 1 [Homo sap... 45 3e-04
gi|239749940 PREDICTED: similar to deformed epidermal autoregula... 45 3e-04
gi|13489073 egl nine homolog 1 [Homo sapiens] 45 3e-04
gi|28872803 myeloid translocation gene on chromosome 16 isoform ... 45 4e-04
gi|28872805 myeloid translocation gene on chromosome 16 isoform ... 45 4e-04
gi|28329422 acute myelogenous leukemia 1 translocation 1 protein... 44 0.001
gi|28329419 acute myelogenous leukemia 1 translocation 1 protein... 44 0.001
gi|28329416 acute myelogenous leukemia 1 translocation 1 protein... 44 0.001
gi|4757916 acute myelogenous leukemia 1 translocation 1 protein ... 44 0.001
gi|225703108 tudor domain containing 3 isoform 2 [Homo sapiens] 42 0.005
>gi|38505161 tudor domain containing 1 [Homo sapiens]
Length = 1189
Score = 2410 bits (6245), Expect = 0.0
Identities = 1189/1189 (100%), Positives = 1189/1189 (100%)
Query: 1 MSVKSPFNVMSRNNLEAPPCKMTEPFNFEKNENKLPPHESLRSPGTLPNHPNFRLKSSEN 60
MSVKSPFNVMSRNNLEAPPCKMTEPFNFEKNENKLPPHESLRSPGTLPNHPNFRLKSSEN
Sbjct: 1 MSVKSPFNVMSRNNLEAPPCKMTEPFNFEKNENKLPPHESLRSPGTLPNHPNFRLKSSEN 60
Query: 61 GNKKNNFLLCEQTKQYLASQEDNSVSSNPNGINGEVVGSKGDRKKLPAGNSVSPPSAESN 120
GNKKNNFLLCEQTKQYLASQEDNSVSSNPNGINGEVVGSKGDRKKLPAGNSVSPPSAESN
Sbjct: 61 GNKKNNFLLCEQTKQYLASQEDNSVSSNPNGINGEVVGSKGDRKKLPAGNSVSPPSAESN 120
Query: 121 SPPKEVNIKPGNNVRPAKSKKLNKLVENSLSISNPGLFTSLGPPLRSTTCHRCGLFGSLR 180
SPPKEVNIKPGNNVRPAKSKKLNKLVENSLSISNPGLFTSLGPPLRSTTCHRCGLFGSLR
Sbjct: 121 SPPKEVNIKPGNNVRPAKSKKLNKLVENSLSISNPGLFTSLGPPLRSTTCHRCGLFGSLR 180
Query: 181 CSQCKQTYYCSTACQRRDWSAHSIVCRPVQPNFHKLENKSSIETKDVEVNNKSDCPLGVT 240
CSQCKQTYYCSTACQRRDWSAHSIVCRPVQPNFHKLENKSSIETKDVEVNNKSDCPLGVT
Sbjct: 181 CSQCKQTYYCSTACQRRDWSAHSIVCRPVQPNFHKLENKSSIETKDVEVNNKSDCPLGVT 240
Query: 241 KEIAIWAERIMFSDLRSLQLKKTMEIKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASLK 300
KEIAIWAERIMFSDLRSLQLKKTMEIKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASLK
Sbjct: 241 KEIAIWAERIMFSDLRSLQLKKTMEIKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASLK 300
Query: 301 ETYANVHEKDYIPVKGEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLN 360
ETYANVHEKDYIPVKGEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLN
Sbjct: 301 ETYANVHEKDYIPVKGEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLN 360
Query: 361 RIYHLNRNIDLFPPCAIKCFVANVIPAEGNWSSDCIKATKPLLMEQYCSIKIVDILEEEV 420
RIYHLNRNIDLFPPCAIKCFVANVIPAEGNWSSDCIKATKPLLMEQYCSIKIVDILEEEV
Sbjct: 361 RIYHLNRNIDLFPPCAIKCFVANVIPAEGNWSSDCIKATKPLLMEQYCSIKIVDILEEEV 420
Query: 421 VTFAVEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPEDVGKMTTENNIVVDK 480
VTFAVEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPEDVGKMTTENNIVVDK
Sbjct: 421 VTFAVEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPEDVGKMTTENNIVVDK 480
Query: 481 SDLIPKVLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDF 540
SDLIPKVLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDF
Sbjct: 481 SDLIPKVLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDF 540
Query: 541 YPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLEL 600
YPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLEL
Sbjct: 541 YPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLEL 600
Query: 601 PMQAIKCVLAGVKPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPH 660
PMQAIKCVLAGVKPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPH
Sbjct: 601 PMQAIKCVLAGVKPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPH 660
Query: 661 VSVSKVLLDAGFAVGEQSMVTDKPSDVKETSVPLGVEGKVNPLEWTWVELGVDQTVDVVV 720
VSVSKVLLDAGFAVGEQSMVTDKPSDVKETSVPLGVEGKVNPLEWTWVELGVDQTVDVVV
Sbjct: 661 VSVSKVLLDAGFAVGEQSMVTDKPSDVKETSVPLGVEGKVNPLEWTWVELGVDQTVDVVV 720
Query: 721 CVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFFAGDGSWY 780
CVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFFAGDGSWY
Sbjct: 721 CVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFFAGDGSWY 780
Query: 781 RALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQSRNKHW 840
RALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQSRNKHW
Sbjct: 781 RALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQSRNKHW 840
Query: 841 SEEAITRFQMCVAGIKLQARVVEVTENGIGVELTDLSTCYPRIISDVLIDEHLVLKSASP 900
SEEAITRFQMCVAGIKLQARVVEVTENGIGVELTDLSTCYPRIISDVLIDEHLVLKSASP
Sbjct: 841 SEEAITRFQMCVAGIKLQARVVEVTENGIGVELTDLSTCYPRIISDVLIDEHLVLKSASP 900
Query: 901 HKDLPNDRLVNKHELQVHVQGLQATSSAEQWKTIELPVDKTIQANVLEIISPNLFYALPK 960
HKDLPNDRLVNKHELQVHVQGLQATSSAEQWKTIELPVDKTIQANVLEIISPNLFYALPK
Sbjct: 901 HKDLPNDRLVNKHELQVHVQGLQATSSAEQWKTIELPVDKTIQANVLEIISPNLFYALPK 960
Query: 961 GMPENQEKLCMLTAELLEYCNAPKSRPPYRPRIGDACCAKYTSDDFWYRAVVLGTSDTDV 1020
GMPENQEKLCMLTAELLEYCNAPKSRPPYRPRIGDACCAKYTSDDFWYRAVVLGTSDTDV
Sbjct: 961 GMPENQEKLCMLTAELLEYCNAPKSRPPYRPRIGDACCAKYTSDDFWYRAVVLGTSDTDV 1020
Query: 1021 EVLYADYGNIETLPLCRVQPITSSHLALPFQIIRCSLEGLMELNGSSSQLIIMLLKNFML 1080
EVLYADYGNIETLPLCRVQPITSSHLALPFQIIRCSLEGLMELNGSSSQLIIMLLKNFML
Sbjct: 1021 EVLYADYGNIETLPLCRVQPITSSHLALPFQIIRCSLEGLMELNGSSSQLIIMLLKNFML 1080
Query: 1081 NQNVMLSVKGITKNVHTVSVEKCSENGTVDVADKLVTFGLAKNITPQRQSALNTEKMYRM 1140
NQNVMLSVKGITKNVHTVSVEKCSENGTVDVADKLVTFGLAKNITPQRQSALNTEKMYRM
Sbjct: 1081 NQNVMLSVKGITKNVHTVSVEKCSENGTVDVADKLVTFGLAKNITPQRQSALNTEKMYRM 1140
Query: 1141 NCCCTELQKQVEKHEHILLFLLNNSTNQNKFIEMKKLLKKTASLGGKPL 1189
NCCCTELQKQVEKHEHILLFLLNNSTNQNKFIEMKKLLKKTASLGGKPL
Sbjct: 1141 NCCCTELQKQVEKHEHILLFLLNNSTNQNKFIEMKKLLKKTASLGGKPL 1189
>gi|169163653 PREDICTED: similar to tudor domain containing 1 [Homo
sapiens]
Length = 2080
Score = 139 bits (349), Expect = 2e-32
Identities = 199/924 (21%), Positives = 376/924 (40%), Gaps = 125/924 (13%)
Query: 226 DVEVNNKSDCPLGVTKEIAIWAERIMFSDLRSLQLKKTMEIKGTVTEFKHPGDFYVQLYS 285
D+ + + + LG K+ ++ + ++ SL + T +K V+ P FY QL
Sbjct: 352 DLLQHKRPELSLG-NKDTSLDIQHVLDKLQPSLSVGSTESVK--VSSALSPSKFYCQLI- 407
Query: 286 SEVLEYMNQLSASLKETYANVHEKDYIPVK--GEVCIAKYTVDQTWNRAIIQNVDVQQKK 343
+ + L+A + Y V ++ G +C+A+ Q W+R I+Q + + +
Sbjct: 408 -KWTPELENLTAHMTLHYDTVCQETSPTCDNFGLLCVARRRNGQ-WHRGILQQL-LPPNQ 464
Query: 344 AHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCFVANVIPAEGNWSSDCIKATKPLL 403
+ ++DYG+ E IP + L ++ L P + C + + + + + K L
Sbjct: 465 VKIWFMDYGSSEAIPSIYVKKLKQDFILVPLFSFPCSLTCLHSPDRDARIFQLSIFKQAL 524
Query: 404 MEQYCSIKIVDILEEEVVTFAVEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENA-DQS 462
+ Q I D ++ + V ++ S +L +G + DSK N ++
Sbjct: 525 LGQVVYAHI-DWFNKDECLYYVTLQTQESTVNSKCLLKTVGTQVLCPMSDSKISNILSET 583
Query: 463 DPEDVGKMTTEN---NIV-----VDKSDLIP-----KVLTLNVGDEFCGVVAHIQTPEDF 509
DV E+ NI ++K ++ K + + + + +A++ P +F
Sbjct: 584 SVSDVNSFAVESFMGNIEWSIDSLNKKGILKVGFPIKTVQMEIEAAYIAFIAYVLNPSNF 643
Query: 510 FCQQLQSGRKLAELQASLSKYCDQLPPRSDFY--PAIGDICCAQFSEDDQWYRASVLAYA 567
+ + + E+ +++K+ D P G CCA++S+D ++YRA V+
Sbjct: 644 WVRTNDHRNEFQEIMKNINKFYDLCENDEMILRKPEPGLFCCARYSKDRRFYRA-VITEI 702
Query: 568 SEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAGVKPSLGIWTPEAICLM 627
+ + V ++DYGN + + + ++P+ ELP A+ C LA + P +WT AI
Sbjct: 703 NGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSLAHIFPVEDLWTKAAIDYF 762
Query: 628 KKLVQNKIITVKVVDKLENSSLVELIDKSETPHVSVSKVLLDAGFA-------------V 674
KKLV NK I ++V+ K ++ V + + ++ V ++L AG+A V
Sbjct: 763 KKLVLNKAILLQVIAKKDDKYTVNIQSVEASENIDVISLMLQAGYAEYFQVELEYFPKSV 822
Query: 675 GEQSMVTDKPS---DVKET---------------------------SVPLGVEGKVNPL- 703
E SM+ + ++K+ S+ + + NP
Sbjct: 823 SEYSMLNSESKNKVNIKKVISALLEGPKSKKYHSNNLVENNLSLPKSLAVNISEFKNPFT 882
Query: 704 -------EWTWVE--LGVDQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQ 754
W + E ++V Y PG+F C + K DL K L E Q
Sbjct: 883 LSVGPESSWPYKEYIFRPGTVLEVKCSCYYGPGDFSCQL-----QCKSEDL-KLLMEQIQ 936
Query: 755 QKLP-NGFKAEIGQPCCAFFAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRM 813
+ EIGQ C G W RA V + + V + FVDYG + V ++L
Sbjct: 937 NYYSIHSDPYEIGQTACV-AKYSGKWCRAAVLTQV-SKEVDIVFVDYGYQKRVLIEDLCA 994
Query: 814 ISSTFLNLPFQGIRCQL----ADIQSRNKHWSEEAITRFQMCVAGIK-----LQARVVEV 864
I+ FL L Q RC L + + W+ +A ++ + + +V +
Sbjct: 995 INPRFLLLESQAFRCCLNHFIEPVSCKLFSWTRKAFRDLWNFISSSRGLLTCIIYALVII 1054
Query: 865 TENGIGVELTDLSTCYPRIISDVLIDEHLVLKSASPHKDLPNDRLVNKHELQVHVQGLQA 924
N + L DL + + E L+ + ++ + L ++ + L +
Sbjct: 1055 HPNHL-YNLVDLQSSF------TSAKEFLMNRGSAQYITL-SETFPSLFSLYSYC----- 1101
Query: 925 TSSAEQWKTIELPVDKTIQANVLEIISPNLFYALPKGMPENQEKLCMLTAELLEYCNAPK 984
+ + + + + + I SP FY + N + L M+ ++ E N +
Sbjct: 1102 ------YSSFNIQIGSEEEVYISHIYSPQKFYC---QLGRNNKDLEMIETKITESVNL-Q 1151
Query: 985 SRPPYRPRIGDACCAKYTSDDFWYRAVVLGT-SDTDVEVLYADYGNIETLPLCRVQPITS 1043
+ P Y C +KY D YRA+ + T S ++ +V + D+GN + + ++ I++
Sbjct: 1152 NFPKYDSNKMRVCISKYVEDGLSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISA 1211
Query: 1044 SH---LALPFQIIRCSLEGLMELN 1064
L P Q I+C L L +++
Sbjct: 1212 QFPELLFTPMQAIKCFLSDLRDVD 1235
Score = 126 bits (316), Expect = 1e-28
Identities = 162/682 (23%), Positives = 292/682 (42%), Gaps = 103/682 (15%)
Query: 264 MEIKGTVTEF----KHPGDFYVQL--YSSEVLEYMNQLSASLKETYANVHEKDYI----P 313
MEI+ F +P +F+V+ + +E E M ++ + ++ E D + P
Sbjct: 624 MEIEAAYIAFIAYVLNPSNFWVRTNDHRNEFQEIMKNINK-----FYDLCENDEMILRKP 678
Query: 314 VKGEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFP 373
G C A+Y+ D+ + RA+I ++ K +V ++DYGN + IP + L P
Sbjct: 679 EPGLFCCARYSKDRRFYRAVI--TEINGYKINVYFLDYGNTDSIPFFDVKILLPEFCELP 736
Query: 374 PCAIKCFVANVIPAEGNWSSDCIKATKPLLMEQYCSIKIVDILEEEVVTFAVEVELPNSG 433
A+ C +A++ P E W+ I K L++ + ++++ +++ VE +
Sbjct: 737 ALAMCCSLAHIFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQSVEASENI 796
Query: 434 KLLDHVLIEMGYG---------LKPSGQDSKKENADQSDPEDVGKMTT-----------E 473
++ ++++ GY S + N++ + ++ K+ +
Sbjct: 797 DVIS-LMLQAGYAEYFQVELEYFPKSVSEYSMLNSESKNKVNIKKVISALLEGPKSKKYH 855
Query: 474 NNIVVDKSDLIPKVL-----------TLNVGDEFC----------GVVAHIQT-----PE 507
+N +V+ + +PK L TL+VG E G V ++ P
Sbjct: 856 SNNLVENNLSLPKSLAVNISEFKNPFTLSVGPESSWPYKEYIFRPGTVLEVKCSCYYGPG 915
Query: 508 DFFCQQLQSGRKLAELQASLSKYCDQLPPRSDFYPAIGDICCAQFSEDDQWYRASVLAYA 567
DF CQ L L + Y SD Y C A++S +W RA+VL
Sbjct: 916 DFSCQLQCKSEDLKLLMEQIQNYYSI---HSDPYEIGQTACVAKYS--GKWCRAAVLTQV 970
Query: 568 SEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVL----AGVKPSLGIWTPEA 623
S+E +V +VDYG + + + LC I P+ L L QA +C L V L WT +A
Sbjct: 971 SKEVDIV-FVDYGYQKRVLIEDLCAINPRFLLLESQAFRCCLNHFIEPVSCKLFSWTRKA 1029
Query: 624 ICLMKKLVQNK------IITVKVVDKLENSSLVELIDKSETPHVSVSKVLLDAGFAVGEQ 677
+ + + II V+ + + L L+D ++ S + L++ G A
Sbjct: 1030 FRDLWNFISSSRGLLTCIIYALVI--IHPNHLYNLVDL-QSSFTSAKEFLMNRGSA---- 1082
Query: 678 SMVTDKPSDVKETSVPLGVEGKVNPLEWTWVELGVDQTVDVVVCVIYSPGEFYCHVLKED 737
+T + S+ N +++G ++ +V + IYSP +FYC + + +
Sbjct: 1083 QYITLSETFPSLFSLYSYCYSSFN------IQIGSEE--EVYISHIYSPQKFYCQLGRNN 1134
Query: 738 ALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFFAGDGSWYRALVKEILPNGHVKVHF 797
K L + + E + + + + C + + DG YRAL + +V+F
Sbjct: 1135 --KDLEMIETKITESVNLQNFPKYDSNKMRVCISKYVEDGLSYRALAIPTDSSSEFQVYF 1192
Query: 798 VDYGNIEEVTADELRMISSTFLNL---PFQGIRCQLADIQSRNKHWSEEAITRFQMCVAG 854
VD+GN + V + LR IS+ F L P Q I+C L+D+ R+ E + F+ G
Sbjct: 1193 VDFGNKQLVGENMLRAISAQFPELLFTPMQAIKCFLSDL--RDVDIPAEISSWFKDNFLG 1250
Query: 855 IKLQARVVEVTENG-IGVELTD 875
L+A ++ +G +G+EL D
Sbjct: 1251 RSLKAIILSQESDGQLGIELYD 1272
Score = 115 bits (289), Expect = 2e-25
Identities = 129/649 (19%), Positives = 263/649 (40%), Gaps = 70/649 (10%)
Query: 544 IGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQ 603
I + C + +W R V+ +E ++ +D G ++ ++ L ELP +
Sbjct: 208 IDEFCLVEERVSGEWQRGRVMEKKNELYTVL-LIDRGEELRVAGPQIASACGNLFELPPR 266
Query: 604 AIKCVLAGVKPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPHVSV 663
+ + A + P W+P+A+ K LV ++V ++ +++ E P +
Sbjct: 267 VVFGIFANILPVGEKWSPKALNYFKSLVG-----IQVKGYVQAILPLQMF-LFEVPKIIS 320
Query: 664 SKVLLDAGFAVGEQS------MVTDKPSDV---------------KETSVPLG-VEGKVN 701
+ L G V S M+ + P + K+TS+ + V K+
Sbjct: 321 QALELQLGRLVDGDSFRLIVEMLEEFPQQMPDLLQHKRPELSLGNKDTSLDIQHVLDKLQ 380
Query: 702 PLEWTWVELGVDQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEH----CQQKL 757
P L V T V V SP +FYC ++K +L +L + H CQ+
Sbjct: 381 P------SLSVGSTESVKVSSALSPSKFYCQLIKWTP--ELENLTAHMTLHYDTVCQETS 432
Query: 758 PNGFKAEIGQPCCAFFAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISST 817
P + C +G W+R +++++LP VK+ F+DYG+ E + + ++ +
Sbjct: 433 PTCDNFGL---LCVARRRNGQWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQD 489
Query: 818 FLNLPFQGIRCQLADIQSRNKHWSEEAITRFQMCVAGIKLQARV-------------VEV 864
F+ +P C L + S ++ ++ F+ + G + A + ++
Sbjct: 490 FILVPLFSFPCSLTCLHSPDRDARIFQLSIFKQALLGQVVYAHIDWFNKDECLYYVTLQT 549
Query: 865 TENGIGVE--LTDLSTCYPRIISDVLIDEHLVLKSASPHKDLPNDRLVNKHELQVHVQGL 922
E+ + + L + T +SD I L S S + + E +
Sbjct: 550 QESTVNSKCLLKTVGTQVLCPMSDSKISNILSETSVSDVNSFAVESFMGNIEWSIDSLNK 609
Query: 923 QATSSAE-QWKTIELPVDKTIQANVLEIISPNLFYALPKGMPENQEKLCMLTAELLEYCN 981
+ KT+++ ++ A + +++P+ F+ +++ + + C
Sbjct: 610 KGILKVGFPIKTVQMEIEAAYIAFIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCE 669
Query: 982 APKSRPPYRPRIGDACCAKYTSDDFWYRAVVLGTSDTDVEVLYADYGNIETLPLCRVQPI 1041
+ +P G CCA+Y+ D +YRAV+ + + V + DYGN +++P V+ +
Sbjct: 670 NDEMILR-KPEPGLFCCARYSKDRRFYRAVITEINGYKINVYFLDYGNTDSIPFFDVKIL 728
Query: 1042 TSSHLALPFQIIRCSLEGLMELNGSSSQLIIMLLKNFMLNQNVMLSVKGITKNVHTVSVE 1101
LP + CSL + + ++ I K +LN+ ++L V + +TV+++
Sbjct: 729 LPEFCELPALAMCCSLAHIFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQ 788
Query: 1102 KCSENGTVDVADKLVTFGLAKNITPQRQ---------SALNTEKMYRMN 1141
+ +DV ++ G A+ + + S LN+E ++N
Sbjct: 789 SVEASENIDVISLMLQAGYAEYFQVELEYFPKSVSEYSMLNSESKNKVN 837
Score = 112 bits (281), Expect = 2e-24
Identities = 187/905 (20%), Positives = 355/905 (39%), Gaps = 122/905 (13%)
Query: 317 EVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCA 376
E C+ + V W R + ++ + + VL ID G E + +I N+ PP
Sbjct: 210 EFCLVEERVSGEWQRGRV--MEKKNELYTVLLIDRGEELRVAGPQIASACGNLFELPPRV 267
Query: 377 IKCFVANVIPAEGNWSSDCIKATKPLL-------MEQYCSIKIVDILEEEVVTFAVEVEL 429
+ AN++P WS + K L+ ++ +++ ++++ A+E++L
Sbjct: 268 VFGIFANILPVGEKWSPKALNYFKSLVGIQVKGYVQAILPLQMFLFEVPKIISQALELQL 327
Query: 430 PNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPE-DVGKMTTENNI--VVDKSDLIPK 486
G+L+D + + + PE +G T +I V+DK L P
Sbjct: 328 ---GRLVDGDSFRLIVEMLEEFPQQMPDLLQHKRPELSLGNKDTSLDIQHVLDK--LQP- 381
Query: 487 VLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSKY----CDQLPPRSDFYP 542
+L+VG V+ +P F+CQ ++ +L L A ++ + C + P D +
Sbjct: 382 --SLSVGSTESVKVSSALSPSKFYCQLIKWTPELENLTAHMTLHYDTVCQETSPTCDNF- 438
Query: 543 AIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPM 602
G +C A+ + QW+R + V + ++DYG+ E + + + + + +P+
Sbjct: 439 --GLLCVAR-RRNGQWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILVPL 495
Query: 603 QAIKCVLAGVKPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPHVS 662
+ C L + + + K+ + +++ + D + +
Sbjct: 496 FSFPCSLTCLHSPDRDARIFQLSIFKQALLGQVVYAHI-DWFNKDECLYYVTLQTQESTV 554
Query: 663 VSKVLLDAGFAVGEQSMVTDKPSDVK----ETSVP----LGVEGKVNPLEWT-------- 706
SK LL VG Q + S + ETSV VE + +EW+
Sbjct: 555 NSKCLLKT---VGTQVLCPMSDSKISNILSETSVSDVNSFAVESFMGNIEWSIDSLNKKG 611
Query: 707 ---------WVELGVDQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEH---CQ 754
V++ ++ + + +P F+ V D + ++ K++ + C+
Sbjct: 612 ILKVGFPIKTVQMEIEAAYIAFIAYVLNPSNFW--VRTNDHRNEFQEIMKNINKFYDLCE 669
Query: 755 QKLPNGFKAEIGQPCCAFFAGDGSWYRALVKEILPNGH-VKVHFVDYGNIEEVTADELRM 813
K E G CCA ++ D +YRA++ EI NG+ + V+F+DYGN + + ++++
Sbjct: 670 NDEMILRKPEPGLFCCARYSKDRRFYRAVITEI--NGYKINVYFLDYGNTDSIPFFDVKI 727
Query: 814 ISSTFLNLPFQGIRCQLADIQSRNKHWSEEAITRFQMCVAGIKLQARVVEVTENGIGVEL 873
+ F LP + C LA I W++ AI F+ V + +V+ ++ V +
Sbjct: 728 LLPEFCELPALAMCCSLAHIFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNI 787
Query: 874 TDLSTCYP-RIISDVL---------IDEHLVLKSASPHKDLPNDRLVNKHELQVHVQGLQ 923
+ +IS +L ++ KS S + L N NK ++ + L
Sbjct: 788 QSVEASENIDVISLMLQAGYAEYFQVELEYFPKSVSEYSML-NSESKNKVNIKKVISALL 846
Query: 924 ATSSAEQWKT-----IELPVDKTIQANVLEIISPNLFYALPKG----------------- 961
++++ + L + K++ N+ E +P P+
Sbjct: 847 EGPKSKKYHSNNLVENNLSLPKSLAVNISEFKNPFTLSVGPESSWPYKEYIFRPGTVLEV 906
Query: 962 --------------MPENQEKLCMLTAELLEYCNAPKSRPPYRPRIGD-ACCAKYTSDDF 1006
+ E L +L ++ Y + PY IG AC AKY+
Sbjct: 907 KCSCYYGPGDFSCQLQCKSEDLKLLMEQIQNYYSIHSD--PY--EIGQTACVAKYSGK-- 960
Query: 1007 WYRAVVLGTSDTDVEVLYADYGNIETLPLCRVQPITSSHLALPFQIIRCSLEGLMELNGS 1066
W RA VL +V++++ DYG + + + + I L L Q RC L +E
Sbjct: 961 WCRAAVLTQVSKEVDIVFVDYGYQKRVLIEDLCAINPRFLLLESQAFRCCLNHFIE--PV 1018
Query: 1067 SSQLIIMLLKNFMLNQNVMLSVKGITKNVHTVSVEKCSENGTVDVADKLVTFGLAKNITP 1126
S +L K F N + S +G+ + ++ N ++ D +F AK
Sbjct: 1019 SCKLFSWTRKAFRDLWNFISSSRGLLTCI-IYALVIIHPNHLYNLVDLQSSFTSAKEFLM 1077
Query: 1127 QRQSA 1131
R SA
Sbjct: 1078 NRGSA 1082
Score = 105 bits (262), Expect = 3e-22
Identities = 145/626 (23%), Positives = 261/626 (41%), Gaps = 70/626 (11%)
Query: 249 RIMFSDLRSLQLKKTMEIKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASLKETYANVHE 308
R DL Q+ ++KG V+ +P +F++QL +E + + +L+ +L T + E
Sbjct: 1426 RPQIKDLPQPQIYLNAKVKGYVSNISNPANFHIQLAENESV--IIRLADALNATARRLRE 1483
Query: 309 KDYI-PVKGEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNR 367
+ + P+ G++ +A+Y+ D RA+I+ + + V +IDYGN I+ ++IY L R
Sbjct: 1484 RKSVKPLVGDLVVAEYSGDNAIYRAVIKKI-LPGNSFEVEFIDYGNSAIVNTSKIYELQR 1542
Query: 368 NIDLFPPCAIKCFVANVIPAEGN--WSSDCIK--ATKPLLMEQYCSI--------KIVDI 415
P I F++ V E + W + +K YC ++ I
Sbjct: 1543 EFLTVPQLGIHAFLSGVKWNEPDEIWDDKTVDYFTSKVHNKTVYCEFLKKHDQKWEVNMI 1602
Query: 416 LEE-----EVVTFAVEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPEDVGKM 470
+E E++ + +L S + VL + ++P + KK +++S+ G M
Sbjct: 1603 CDEKCVINELLKWKACSKLQKSALQMPQVLSQK---VRPGDNEMKKGKSNESE----GSM 1655
Query: 471 TTENNIVVDKSDLIPKVLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSKY 530
+ + IP + +G + ++ F+ + ++ + L++L ++K
Sbjct: 1656 NSNQQLF-----KIP-LEEFKLGQLEKAEMLNVSKSGRFYVKLSKNKKILSDLIVLITKE 1709
Query: 531 CDQLPPRSDFYPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRL 590
+ P S G C A+ +W+R+ V ++ VLV VD G +EI+ +
Sbjct: 1710 EKKSPFLSMESIEKGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCGIYEIVPVCNT 1769
Query: 591 CPIIPKLLELPMQAIKCVLAGVKPSLGIWTPEAICLMKKLVQNKIITVKVVDK------- 643
+ ++ +P QA+ C + S I CL L N I+ +K +D
Sbjct: 1770 KLLSNEIRNIPRQAVPCKWIWFENSKNI---SFECLFADLEIN-ILFLKYLDAVWEVEIL 1825
Query: 644 LENSSLVELIDKSETPHVSVSKVLLDAGFAVGEQSMVTDKPSDVKETSVPLGVEGKVNPL 703
+++ L+E ++ + P V +K+ L A +S +K
Sbjct: 1826 VDDLLLLEYLNLNTVP-VEENKLRL-AEIVYNIESKTPVSSCTIK--------------- 1868
Query: 704 EWTWVELGVDQTVDVVVCVIYSPGEFYCHVLK-EDALKKLNDLNKSLAEHCQQKLPNGFK 762
+TWV+ D+ + + P +F + D +K L L L E Q LP F
Sbjct: 1869 SFTWVQFQNDRQYSGIATAVSDPSDFSIQLEDFFDIMKYLFMLLSDLPE-TLQTLPQEFI 1927
Query: 763 AEIGQPCCAFFAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADE---LRMISSTFL 819
G C + + W R + E+ P V VDYG + E L+++ L
Sbjct: 1928 IP-GSSCLFKYKSEDQWNRVEISEVSPQSLCLV-LVDYGFSFYIRYSEIINLKVVPEELL 1985
Query: 820 NLPFQGIRCQLADI-QSRNKHWSEEA 844
NLP C L I ++ KHWSEEA
Sbjct: 1986 NLPRLSYPCILYGILPAKGKHWSEEA 2011
Score = 96.3 bits (238), Expect = 2e-19
Identities = 137/650 (21%), Positives = 257/650 (39%), Gaps = 62/650 (9%)
Query: 498 GVVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDFYPAIGDICCAQFSEDDQ 557
G V++I P +F Q ++ + L +L+ +L R P +GD+ A++S D+
Sbjct: 1445 GYVSNISNPANFHIQLAENESVIIRLADALNATARRLRERKSVKPLVGDLVVAEYSGDNA 1504
Query: 558 WYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAGVK--PS 615
YRA + S V ++DYGN I++ ++ + + L +P I L+GVK
Sbjct: 1505 IYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKIYELQREFLTVPQLGIHAFLSGVKWNEP 1564
Query: 616 LGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELI----------------DKSETP 659
IW + + V NK + + + K + V +I K +
Sbjct: 1565 DEIWDDKTVDYFTSKVHNKTVYCEFLKKHDQKWEVNMICDEKCVINELLKWKACSKLQKS 1624
Query: 660 HVSVSKVLLDAGFAVGEQSMVTDKPSDVKETSVPLGVEGKVNPLEWTWVELGVDQTVDVV 719
+ + +V L G+ M K S+ E S+ + PLE E + Q
Sbjct: 1625 ALQMPQV-LSQKVRPGDNEMKKGK-SNESEGSMNSNQQLFKIPLE----EFKLGQLEKAE 1678
Query: 720 VCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLP--NGFKAEIGQPCCAFFAGDG 777
+ + G FY + K K L+DL + + ++K P + E G C A
Sbjct: 1679 MLNVSKSGRFYVKLSKNK--KILSDLIVLITKE-EKKSPFLSMESIEKGLECLAKSKNTL 1735
Query: 778 SWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQSRN 837
W+R+ V+E + V V VD G E V +++S+ N+P Q + C+ ++
Sbjct: 1736 KWHRSKVEEKYVDDKVLVFLVDCGIYEIVPVCNTKLLSNEIRNIPRQAVPCKWIWFENSK 1795
Query: 838 KHWSEEAITRFQMCVAGIKLQARVVEVTENGIGVELTDLSTCYPRIISDVLIDEHLVLKS 897
E ++ + +K V EV ++L+D+ L+L+
Sbjct: 1796 NISFECLFADLEINILFLKYLDAVWEV---------------------EILVDDLLLLEY 1834
Query: 898 ASPHKDLPNDRLVNKHELQVHVQGLQATSSA--EQWKTIELPVDKTIQANVLEIISPNLF 955
+ + + + E+ +++ SS + + ++ D+ + P+ F
Sbjct: 1835 LNLNTVPVEENKLRLAEIVYNIESKTPVSSCTIKSFTWVQFQNDRQYSGIATAVSDPSDF 1894
Query: 956 YALPKGMPENQEKLCMLTAELLEYCNAPKSRPPYRPRIGDACCAKYTSDDFWYRAVVLGT 1015
+ + + L ML ++L E ++ P G +C KY S+D W R +
Sbjct: 1895 SIQLEDFFDIMKYLFMLLSDLPE---TLQTLPQEFIIPGSSCLFKYKSEDQWNRVEISEV 1951
Query: 1016 SDTDVEVLYADYG---NIETLPLCRVQPITSSHLALPFQIIRCSLEGLMELNGSS-SQLI 1071
S + ++ DYG I + ++ + L LP C L G++ G S+
Sbjct: 1952 SPQSLCLVLVDYGFSFYIRYSEIINLKVVPEELLNLPRLSYPCILYGILPAKGKHWSEEA 2011
Query: 1072 IMLLKNFMLNQNVMLSVKGITKNVHTVSVEKCSENGTVDVADKLVTFGLA 1121
+ ++F+ +++ + + V+ E ++AD LV GLA
Sbjct: 2012 KIFFRDFLSKPDLVFQFREYHSET-KLKVDVIHEKN--NLADILVASGLA 2058
Score = 71.6 bits (174), Expect = 4e-12
Identities = 124/590 (21%), Positives = 238/590 (40%), Gaps = 82/590 (13%)
Query: 268 GTVTEFK-----HPGDFYVQLY--SSEVLEYMNQLSASLKETYANVHEKDYIPVKGEVCI 320
GTV E K PGDF QL S ++ M Q+ + Y ++H Y + C+
Sbjct: 901 GTVLEVKCSCYYGPGDFSCQLQCKSEDLKLLMEQI-----QNYYSIHSDPY-EIGQTACV 954
Query: 321 AKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCF 380
AKY+ W RA + + K+ ++++DYG ++ + + + +N L A +C
Sbjct: 955 AKYS--GKWCRAAV--LTQVSKEVDIVFVDYGYQKRVLIEDLCAINPRFLLLESQAFRCC 1010
Query: 381 VANVI-PAEGNWSSDCIKATKPLLMEQYCSIKIVDILEEEVVTFAVEVELPNS-GKLLDH 438
+ + I P S KA + L S ++ + +A+ + PN L+D
Sbjct: 1011 LNHFIEPVSCKLFSWTRKAFRDLWNFISSSRGLLTC-----IIYALVIIHPNHLYNLVD- 1064
Query: 439 VLIEMGYGLKPSGQDSKKENADQSDPEDVGKMTTENNIVVDKSDLIPKVLTLNVGDEFCG 498
L+ S +K+ ++ + + T ++ S + +G E
Sbjct: 1065 --------LQSSFTSAKEFLMNRGSAQYITLSETFPSLFSLYSYCYSS-FNIQIGSEEEV 1115
Query: 499 VVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCD-QLPPRSDFYPAIGDICCAQFSEDDQ 557
++HI +P+ F+CQ ++ + L ++ +++ + Q P+ D +C +++ ED
Sbjct: 1116 YISHIYSPQKFYCQLGRNNKDLEMIETKITESVNLQNFPKYDSNKM--RVCISKYVEDGL 1173
Query: 558 WYRASVLAYASEESVLVGYVDYGNFEILS---LMRLCPIIPKLLELPMQAIKCVLAGVKP 614
YRA + S V +VD+GN +++ L + P+LL PMQAIKC L+ ++
Sbjct: 1174 SYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIKCFLSDLR- 1232
Query: 615 SLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPHVSVSKVLLDAGFAV 674
+ I + + + + + + + +EL D S+ + + +L G
Sbjct: 1233 DVDIPAEISSWFKDNFLGRSLKAIILSQESDGQLGIELYDGSQYINEKIKVLLHAYGKRH 1292
Query: 675 GEQSMVTDKPSDVKETS-VPLGVEGKV----------NPLEWTWVELGVDQTVDVVVCVI 723
+Q+ +K + + E ++GK P T+ E +DQ +
Sbjct: 1293 CDQACCMEKSNKINENKRFTTSLKGKTGNNYRHNVINKPSPVTYSERKIDQ--------L 1344
Query: 724 YSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFFAGDGSWYRAL 783
P + LK K+ ++K+ + L +G K P A
Sbjct: 1345 MHPKNIHARFLKPSVCYKMEPVSKN---KMKTSLNDGLKGIKIVPGAA------------ 1389
Query: 784 VKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADI 833
IL N V +++ V+ +R ++ T P+ IR Q+ D+
Sbjct: 1390 --HILENRR-----VGQKSVKVVSQSFIRALNQTTSQNPYDLIRPQIKDL 1432
>gi|169164192 PREDICTED: similar to tudor domain containing 1 [Homo
sapiens]
Length = 2080
Score = 139 bits (349), Expect = 2e-32
Identities = 199/924 (21%), Positives = 376/924 (40%), Gaps = 125/924 (13%)
Query: 226 DVEVNNKSDCPLGVTKEIAIWAERIMFSDLRSLQLKKTMEIKGTVTEFKHPGDFYVQLYS 285
D+ + + + LG K+ ++ + ++ SL + T +K V+ P FY QL
Sbjct: 352 DLLQHKRPELSLG-NKDTSLDIQHVLDKLQPSLSVGSTESVK--VSSALSPSKFYCQLI- 407
Query: 286 SEVLEYMNQLSASLKETYANVHEKDYIPVK--GEVCIAKYTVDQTWNRAIIQNVDVQQKK 343
+ + L+A + Y V ++ G +C+A+ Q W+R I+Q + + +
Sbjct: 408 -KWTPELENLTAHMTLHYDTVCQETSPTCDNFGLLCVARRRNGQ-WHRGILQQL-LPPNQ 464
Query: 344 AHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCFVANVIPAEGNWSSDCIKATKPLL 403
+ ++DYG+ E IP + L ++ L P + C + + + + + K L
Sbjct: 465 VKIWFMDYGSSEAIPSIYVKKLKQDFILVPLFSFPCSLTCLHSPDRDARIFQLSIFKQAL 524
Query: 404 MEQYCSIKIVDILEEEVVTFAVEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENA-DQS 462
+ Q I D ++ + V ++ S +L +G + DSK N ++
Sbjct: 525 LGQVVYAHI-DWFNKDECLYYVTLQTQESTVNSKCLLKTVGTQVLCPMSDSKISNILSET 583
Query: 463 DPEDVGKMTTEN---NIV-----VDKSDLIP-----KVLTLNVGDEFCGVVAHIQTPEDF 509
DV E+ NI ++K ++ K + + + + +A++ P +F
Sbjct: 584 SVSDVNSFAVESFMGNIEWSIDSLNKKGILKVGFPIKTVQMEIEAAYIAFIAYVLNPSNF 643
Query: 510 FCQQLQSGRKLAELQASLSKYCDQLPPRSDFY--PAIGDICCAQFSEDDQWYRASVLAYA 567
+ + + E+ +++K+ D P G CCA++S+D ++YRA V+
Sbjct: 644 WVRTNDHRNEFQEIMKNINKFYDLCENDEMILRKPEPGLFCCARYSKDRRFYRA-VITEI 702
Query: 568 SEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAGVKPSLGIWTPEAICLM 627
+ + V ++DYGN + + + ++P+ ELP A+ C LA + P +WT AI
Sbjct: 703 NGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSLAHIFPVEDLWTKAAIDYF 762
Query: 628 KKLVQNKIITVKVVDKLENSSLVELIDKSETPHVSVSKVLLDAGFA-------------V 674
KKLV NK I ++V+ K ++ V + + ++ V ++L AG+A V
Sbjct: 763 KKLVLNKAILLQVIAKKDDKYTVNIQSVEASENIDVISLMLQAGYAEYFQVELEYFPKSV 822
Query: 675 GEQSMVTDKPS---DVKET---------------------------SVPLGVEGKVNPL- 703
E SM+ + ++K+ S+ + + NP
Sbjct: 823 SEYSMLNSESKNKVNIKKVISALLEGPKSKKYHSNNLVENNLSLPKSLAVNISEFKNPFT 882
Query: 704 -------EWTWVE--LGVDQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQ 754
W + E ++V Y PG+F C + K DL K L E Q
Sbjct: 883 LSVGPESSWPYKEYIFRPGTVLEVKCSCYYGPGDFSCQL-----QCKSEDL-KLLMEQIQ 936
Query: 755 QKLP-NGFKAEIGQPCCAFFAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRM 813
+ EIGQ C G W RA V + + V + FVDYG + V ++L
Sbjct: 937 NYYSIHSDPYEIGQTACV-AKYSGKWCRAAVLTQV-SKEVDIVFVDYGYQKRVLIEDLCA 994
Query: 814 ISSTFLNLPFQGIRCQL----ADIQSRNKHWSEEAITRFQMCVAGIK-----LQARVVEV 864
I+ FL L Q RC L + + W+ +A ++ + + +V +
Sbjct: 995 INPRFLLLESQAFRCCLNHFIEPVSCKLFSWTRKAFRDLWNFISSSRGLLTCIIYALVII 1054
Query: 865 TENGIGVELTDLSTCYPRIISDVLIDEHLVLKSASPHKDLPNDRLVNKHELQVHVQGLQA 924
N + L DL + + E L+ + ++ + L ++ + L +
Sbjct: 1055 HPNHL-YNLVDLQSSF------TSAKEFLMNRGSAQYITL-SETFPSLFSLYSYC----- 1101
Query: 925 TSSAEQWKTIELPVDKTIQANVLEIISPNLFYALPKGMPENQEKLCMLTAELLEYCNAPK 984
+ + + + + + I SP FY + N + L M+ ++ E N +
Sbjct: 1102 ------YSSFNIQIGSEEEVYISHIYSPQKFYC---QLGRNNKDLEMIETKITESVNL-Q 1151
Query: 985 SRPPYRPRIGDACCAKYTSDDFWYRAVVLGT-SDTDVEVLYADYGNIETLPLCRVQPITS 1043
+ P Y C +KY D YRA+ + T S ++ +V + D+GN + + ++ I++
Sbjct: 1152 NFPKYDSNKMRVCISKYVEDGLSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISA 1211
Query: 1044 SH---LALPFQIIRCSLEGLMELN 1064
L P Q I+C L L +++
Sbjct: 1212 QFPELLFTPMQAIKCFLSDLRDVD 1235
Score = 126 bits (316), Expect = 1e-28
Identities = 162/682 (23%), Positives = 292/682 (42%), Gaps = 103/682 (15%)
Query: 264 MEIKGTVTEF----KHPGDFYVQL--YSSEVLEYMNQLSASLKETYANVHEKDYI----P 313
MEI+ F +P +F+V+ + +E E M ++ + ++ E D + P
Sbjct: 624 MEIEAAYIAFIAYVLNPSNFWVRTNDHRNEFQEIMKNINK-----FYDLCENDEMILRKP 678
Query: 314 VKGEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFP 373
G C A+Y+ D+ + RA+I ++ K +V ++DYGN + IP + L P
Sbjct: 679 EPGLFCCARYSKDRRFYRAVI--TEINGYKINVYFLDYGNTDSIPFFDVKILLPEFCELP 736
Query: 374 PCAIKCFVANVIPAEGNWSSDCIKATKPLLMEQYCSIKIVDILEEEVVTFAVEVELPNSG 433
A+ C +A++ P E W+ I K L++ + ++++ +++ VE +
Sbjct: 737 ALAMCCSLAHIFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQSVEASENI 796
Query: 434 KLLDHVLIEMGYG---------LKPSGQDSKKENADQSDPEDVGKMTT-----------E 473
++ ++++ GY S + N++ + ++ K+ +
Sbjct: 797 DVIS-LMLQAGYAEYFQVELEYFPKSVSEYSMLNSESKNKVNIKKVISALLEGPKSKKYH 855
Query: 474 NNIVVDKSDLIPKVL-----------TLNVGDEFC----------GVVAHIQT-----PE 507
+N +V+ + +PK L TL+VG E G V ++ P
Sbjct: 856 SNNLVENNLSLPKSLAVNISEFKNPFTLSVGPESSWPYKEYIFRPGTVLEVKCSCYYGPG 915
Query: 508 DFFCQQLQSGRKLAELQASLSKYCDQLPPRSDFYPAIGDICCAQFSEDDQWYRASVLAYA 567
DF CQ L L + Y SD Y C A++S +W RA+VL
Sbjct: 916 DFSCQLQCKSEDLKLLMEQIQNYYSI---HSDPYEIGQTACVAKYS--GKWCRAAVLTQV 970
Query: 568 SEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVL----AGVKPSLGIWTPEA 623
S+E +V +VDYG + + + LC I P+ L L QA +C L V L WT +A
Sbjct: 971 SKEVDIV-FVDYGYQKRVLIEDLCAINPRFLLLESQAFRCCLNHFIEPVSCKLFSWTRKA 1029
Query: 624 ICLMKKLVQNK------IITVKVVDKLENSSLVELIDKSETPHVSVSKVLLDAGFAVGEQ 677
+ + + II V+ + + L L+D ++ S + L++ G A
Sbjct: 1030 FRDLWNFISSSRGLLTCIIYALVI--IHPNHLYNLVDL-QSSFTSAKEFLMNRGSA---- 1082
Query: 678 SMVTDKPSDVKETSVPLGVEGKVNPLEWTWVELGVDQTVDVVVCVIYSPGEFYCHVLKED 737
+T + S+ N +++G ++ +V + IYSP +FYC + + +
Sbjct: 1083 QYITLSETFPSLFSLYSYCYSSFN------IQIGSEE--EVYISHIYSPQKFYCQLGRNN 1134
Query: 738 ALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFFAGDGSWYRALVKEILPNGHVKVHF 797
K L + + E + + + + C + + DG YRAL + +V+F
Sbjct: 1135 --KDLEMIETKITESVNLQNFPKYDSNKMRVCISKYVEDGLSYRALAIPTDSSSEFQVYF 1192
Query: 798 VDYGNIEEVTADELRMISSTFLNL---PFQGIRCQLADIQSRNKHWSEEAITRFQMCVAG 854
VD+GN + V + LR IS+ F L P Q I+C L+D+ R+ E + F+ G
Sbjct: 1193 VDFGNKQLVGENMLRAISAQFPELLFTPMQAIKCFLSDL--RDVDIPAEISSWFKDNFLG 1250
Query: 855 IKLQARVVEVTENG-IGVELTD 875
L+A ++ +G +G+EL D
Sbjct: 1251 RSLKAIILSQESDGQLGIELYD 1272
Score = 115 bits (289), Expect = 2e-25
Identities = 129/649 (19%), Positives = 263/649 (40%), Gaps = 70/649 (10%)
Query: 544 IGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQ 603
I + C + +W R V+ +E ++ +D G ++ ++ L ELP +
Sbjct: 208 IDEFCLVEERVSGEWQRGRVMEKKNELYTVL-LIDRGEELRVAGPQIASACGNLFELPPR 266
Query: 604 AIKCVLAGVKPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPHVSV 663
+ + A + P W+P+A+ K LV ++V ++ +++ E P +
Sbjct: 267 VVFGIFANILPVGEKWSPKALNYFKSLVG-----IQVKGYVQAILPLQMF-LFEVPKIIS 320
Query: 664 SKVLLDAGFAVGEQS------MVTDKPSDV---------------KETSVPLG-VEGKVN 701
+ L G V S M+ + P + K+TS+ + V K+
Sbjct: 321 QALELQLGRLVDGDSFRLIVEMLEEFPQQMPDLLQHKRPELSLGNKDTSLDIQHVLDKLQ 380
Query: 702 PLEWTWVELGVDQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEH----CQQKL 757
P L V T V V SP +FYC ++K +L +L + H CQ+
Sbjct: 381 P------SLSVGSTESVKVSSALSPSKFYCQLIKWTP--ELENLTAHMTLHYDTVCQETS 432
Query: 758 PNGFKAEIGQPCCAFFAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISST 817
P + C +G W+R +++++LP VK+ F+DYG+ E + + ++ +
Sbjct: 433 PTCDNFGL---LCVARRRNGQWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQD 489
Query: 818 FLNLPFQGIRCQLADIQSRNKHWSEEAITRFQMCVAGIKLQARV-------------VEV 864
F+ +P C L + S ++ ++ F+ + G + A + ++
Sbjct: 490 FILVPLFSFPCSLTCLHSPDRDARIFQLSIFKQALLGQVVYAHIDWFNKDECLYYVTLQT 549
Query: 865 TENGIGVE--LTDLSTCYPRIISDVLIDEHLVLKSASPHKDLPNDRLVNKHELQVHVQGL 922
E+ + + L + T +SD I L S S + + E +
Sbjct: 550 QESTVNSKCLLKTVGTQVLCPMSDSKISNILSETSVSDVNSFAVESFMGNIEWSIDSLNK 609
Query: 923 QATSSAE-QWKTIELPVDKTIQANVLEIISPNLFYALPKGMPENQEKLCMLTAELLEYCN 981
+ KT+++ ++ A + +++P+ F+ +++ + + C
Sbjct: 610 KGILKVGFPIKTVQMEIEAAYIAFIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCE 669
Query: 982 APKSRPPYRPRIGDACCAKYTSDDFWYRAVVLGTSDTDVEVLYADYGNIETLPLCRVQPI 1041
+ +P G CCA+Y+ D +YRAV+ + + V + DYGN +++P V+ +
Sbjct: 670 NDEMILR-KPEPGLFCCARYSKDRRFYRAVITEINGYKINVYFLDYGNTDSIPFFDVKIL 728
Query: 1042 TSSHLALPFQIIRCSLEGLMELNGSSSQLIIMLLKNFMLNQNVMLSVKGITKNVHTVSVE 1101
LP + CSL + + ++ I K +LN+ ++L V + +TV+++
Sbjct: 729 LPEFCELPALAMCCSLAHIFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQ 788
Query: 1102 KCSENGTVDVADKLVTFGLAKNITPQRQ---------SALNTEKMYRMN 1141
+ +DV ++ G A+ + + S LN+E ++N
Sbjct: 789 SVEASENIDVISLMLQAGYAEYFQVELEYFPKSVSEYSMLNSESKNKVN 837
Score = 112 bits (281), Expect = 2e-24
Identities = 187/905 (20%), Positives = 355/905 (39%), Gaps = 122/905 (13%)
Query: 317 EVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCA 376
E C+ + V W R + ++ + + VL ID G E + +I N+ PP
Sbjct: 210 EFCLVEERVSGEWQRGRV--MEKKNELYTVLLIDRGEELRVAGPQIASACGNLFELPPRV 267
Query: 377 IKCFVANVIPAEGNWSSDCIKATKPLL-------MEQYCSIKIVDILEEEVVTFAVEVEL 429
+ AN++P WS + K L+ ++ +++ ++++ A+E++L
Sbjct: 268 VFGIFANILPVGEKWSPKALNYFKSLVGIQVKGYVQAILPLQMFLFEVPKIISQALELQL 327
Query: 430 PNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPE-DVGKMTTENNI--VVDKSDLIPK 486
G+L+D + + + PE +G T +I V+DK L P
Sbjct: 328 ---GRLVDGDSFRLIVEMLEEFPQQMPDLLQHKRPELSLGNKDTSLDIQHVLDK--LQP- 381
Query: 487 VLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSKY----CDQLPPRSDFYP 542
+L+VG V+ +P F+CQ ++ +L L A ++ + C + P D +
Sbjct: 382 --SLSVGSTESVKVSSALSPSKFYCQLIKWTPELENLTAHMTLHYDTVCQETSPTCDNF- 438
Query: 543 AIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPM 602
G +C A+ + QW+R + V + ++DYG+ E + + + + + +P+
Sbjct: 439 --GLLCVAR-RRNGQWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILVPL 495
Query: 603 QAIKCVLAGVKPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPHVS 662
+ C L + + + K+ + +++ + D + +
Sbjct: 496 FSFPCSLTCLHSPDRDARIFQLSIFKQALLGQVVYAHI-DWFNKDECLYYVTLQTQESTV 554
Query: 663 VSKVLLDAGFAVGEQSMVTDKPSDVK----ETSVP----LGVEGKVNPLEWT-------- 706
SK LL VG Q + S + ETSV VE + +EW+
Sbjct: 555 NSKCLLKT---VGTQVLCPMSDSKISNILSETSVSDVNSFAVESFMGNIEWSIDSLNKKG 611
Query: 707 ---------WVELGVDQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEH---CQ 754
V++ ++ + + +P F+ V D + ++ K++ + C+
Sbjct: 612 ILKVGFPIKTVQMEIEAAYIAFIAYVLNPSNFW--VRTNDHRNEFQEIMKNINKFYDLCE 669
Query: 755 QKLPNGFKAEIGQPCCAFFAGDGSWYRALVKEILPNGH-VKVHFVDYGNIEEVTADELRM 813
K E G CCA ++ D +YRA++ EI NG+ + V+F+DYGN + + ++++
Sbjct: 670 NDEMILRKPEPGLFCCARYSKDRRFYRAVITEI--NGYKINVYFLDYGNTDSIPFFDVKI 727
Query: 814 ISSTFLNLPFQGIRCQLADIQSRNKHWSEEAITRFQMCVAGIKLQARVVEVTENGIGVEL 873
+ F LP + C LA I W++ AI F+ V + +V+ ++ V +
Sbjct: 728 LLPEFCELPALAMCCSLAHIFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNI 787
Query: 874 TDLSTCYP-RIISDVL---------IDEHLVLKSASPHKDLPNDRLVNKHELQVHVQGLQ 923
+ +IS +L ++ KS S + L N NK ++ + L
Sbjct: 788 QSVEASENIDVISLMLQAGYAEYFQVELEYFPKSVSEYSML-NSESKNKVNIKKVISALL 846
Query: 924 ATSSAEQWKT-----IELPVDKTIQANVLEIISPNLFYALPKG----------------- 961
++++ + L + K++ N+ E +P P+
Sbjct: 847 EGPKSKKYHSNNLVENNLSLPKSLAVNISEFKNPFTLSVGPESSWPYKEYIFRPGTVLEV 906
Query: 962 --------------MPENQEKLCMLTAELLEYCNAPKSRPPYRPRIGD-ACCAKYTSDDF 1006
+ E L +L ++ Y + PY IG AC AKY+
Sbjct: 907 KCSCYYGPGDFSCQLQCKSEDLKLLMEQIQNYYSIHSD--PY--EIGQTACVAKYSGK-- 960
Query: 1007 WYRAVVLGTSDTDVEVLYADYGNIETLPLCRVQPITSSHLALPFQIIRCSLEGLMELNGS 1066
W RA VL +V++++ DYG + + + + I L L Q RC L +E
Sbjct: 961 WCRAAVLTQVSKEVDIVFVDYGYQKRVLIEDLCAINPRFLLLESQAFRCCLNHFIE--PV 1018
Query: 1067 SSQLIIMLLKNFMLNQNVMLSVKGITKNVHTVSVEKCSENGTVDVADKLVTFGLAKNITP 1126
S +L K F N + S +G+ + ++ N ++ D +F AK
Sbjct: 1019 SCKLFSWTRKAFRDLWNFISSSRGLLTCI-IYALVIIHPNHLYNLVDLQSSFTSAKEFLM 1077
Query: 1127 QRQSA 1131
R SA
Sbjct: 1078 NRGSA 1082
Score = 105 bits (262), Expect = 3e-22
Identities = 145/626 (23%), Positives = 261/626 (41%), Gaps = 70/626 (11%)
Query: 249 RIMFSDLRSLQLKKTMEIKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASLKETYANVHE 308
R DL Q+ ++KG V+ +P +F++QL +E + + +L+ +L T + E
Sbjct: 1426 RPQIKDLPQPQIYLNAKVKGYVSNISNPANFHIQLAENESV--IIRLADALNATARRLRE 1483
Query: 309 KDYI-PVKGEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNR 367
+ + P+ G++ +A+Y+ D RA+I+ + + V +IDYGN I+ ++IY L R
Sbjct: 1484 RKSVKPLVGDLVVAEYSGDNAIYRAVIKKI-LPGNSFEVEFIDYGNSAIVNTSKIYELQR 1542
Query: 368 NIDLFPPCAIKCFVANVIPAEGN--WSSDCIK--ATKPLLMEQYCSI--------KIVDI 415
P I F++ V E + W + +K YC ++ I
Sbjct: 1543 EFLTVPQLGIHAFLSGVKWNEPDEIWDDKTVDYFTSKVHNKTVYCEFLKKHDQKWEVNMI 1602
Query: 416 LEE-----EVVTFAVEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPEDVGKM 470
+E E++ + +L S + VL + ++P + KK +++S+ G M
Sbjct: 1603 CDEKCVINELLKWKACSKLQKSALQMPQVLSQK---VRPGDNEMKKGKSNESE----GSM 1655
Query: 471 TTENNIVVDKSDLIPKVLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSKY 530
+ + IP + +G + ++ F+ + ++ + L++L ++K
Sbjct: 1656 NSNQQLF-----KIP-LEEFKLGQLEKAEMLNVSKSGRFYVKLSKNKKILSDLIVLITKE 1709
Query: 531 CDQLPPRSDFYPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRL 590
+ P S G C A+ +W+R+ V ++ VLV VD G +EI+ +
Sbjct: 1710 EKKSPFLSMESIEKGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCGIYEIVPVCNT 1769
Query: 591 CPIIPKLLELPMQAIKCVLAGVKPSLGIWTPEAICLMKKLVQNKIITVKVVDK------- 643
+ ++ +P QA+ C + S I CL L N I+ +K +D
Sbjct: 1770 KLLSNEIRNIPRQAVPCKWIWFENSKNI---SFECLFADLEIN-ILFLKYLDAVWEVEIL 1825
Query: 644 LENSSLVELIDKSETPHVSVSKVLLDAGFAVGEQSMVTDKPSDVKETSVPLGVEGKVNPL 703
+++ L+E ++ + P V +K+ L A +S +K
Sbjct: 1826 VDDLLLLEYLNLNTVP-VEENKLRL-AEIVYNIESKTPVSSCTIK--------------- 1868
Query: 704 EWTWVELGVDQTVDVVVCVIYSPGEFYCHVLK-EDALKKLNDLNKSLAEHCQQKLPNGFK 762
+TWV+ D+ + + P +F + D +K L L L E Q LP F
Sbjct: 1869 SFTWVQFQNDRQYSGIATAVSDPSDFSIQLEDFFDIMKYLFMLLSDLPE-TLQTLPQEFI 1927
Query: 763 AEIGQPCCAFFAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADE---LRMISSTFL 819
G C + + W R + E+ P V VDYG + E L+++ L
Sbjct: 1928 IP-GSSCLFKYKSEDQWNRVEISEVSPQSLCLV-LVDYGFSFYIRYSEIINLKVVPEELL 1985
Query: 820 NLPFQGIRCQLADI-QSRNKHWSEEA 844
NLP C L I ++ KHWSEEA
Sbjct: 1986 NLPRLSYPCILYGILPAKGKHWSEEA 2011
Score = 96.3 bits (238), Expect = 2e-19
Identities = 137/650 (21%), Positives = 257/650 (39%), Gaps = 62/650 (9%)
Query: 498 GVVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDFYPAIGDICCAQFSEDDQ 557
G V++I P +F Q ++ + L +L+ +L R P +GD+ A++S D+
Sbjct: 1445 GYVSNISNPANFHIQLAENESVIIRLADALNATARRLRERKSVKPLVGDLVVAEYSGDNA 1504
Query: 558 WYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAGVK--PS 615
YRA + S V ++DYGN I++ ++ + + L +P I L+GVK
Sbjct: 1505 IYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKIYELQREFLTVPQLGIHAFLSGVKWNEP 1564
Query: 616 LGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELI----------------DKSETP 659
IW + + V NK + + + K + V +I K +
Sbjct: 1565 DEIWDDKTVDYFTSKVHNKTVYCEFLKKHDQKWEVNMICDEKCVINELLKWKACSKLQKS 1624
Query: 660 HVSVSKVLLDAGFAVGEQSMVTDKPSDVKETSVPLGVEGKVNPLEWTWVELGVDQTVDVV 719
+ + +V L G+ M K S+ E S+ + PLE E + Q
Sbjct: 1625 ALQMPQV-LSQKVRPGDNEMKKGK-SNESEGSMNSNQQLFKIPLE----EFKLGQLEKAE 1678
Query: 720 VCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLP--NGFKAEIGQPCCAFFAGDG 777
+ + G FY + K K L+DL + + ++K P + E G C A
Sbjct: 1679 MLNVSKSGRFYVKLSKNK--KILSDLIVLITKE-EKKSPFLSMESIEKGLECLAKSKNTL 1735
Query: 778 SWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQSRN 837
W+R+ V+E + V V VD G E V +++S+ N+P Q + C+ ++
Sbjct: 1736 KWHRSKVEEKYVDDKVLVFLVDCGIYEIVPVCNTKLLSNEIRNIPRQAVPCKWIWFENSK 1795
Query: 838 KHWSEEAITRFQMCVAGIKLQARVVEVTENGIGVELTDLSTCYPRIISDVLIDEHLVLKS 897
E ++ + +K V EV ++L+D+ L+L+
Sbjct: 1796 NISFECLFADLEINILFLKYLDAVWEV---------------------EILVDDLLLLEY 1834
Query: 898 ASPHKDLPNDRLVNKHELQVHVQGLQATSSA--EQWKTIELPVDKTIQANVLEIISPNLF 955
+ + + + E+ +++ SS + + ++ D+ + P+ F
Sbjct: 1835 LNLNTVPVEENKLRLAEIVYNIESKTPVSSCTIKSFTWVQFQNDRQYSGIATAVSDPSDF 1894
Query: 956 YALPKGMPENQEKLCMLTAELLEYCNAPKSRPPYRPRIGDACCAKYTSDDFWYRAVVLGT 1015
+ + + L ML ++L E ++ P G +C KY S+D W R +
Sbjct: 1895 SIQLEDFFDIMKYLFMLLSDLPE---TLQTLPQEFIIPGSSCLFKYKSEDQWNRVEISEV 1951
Query: 1016 SDTDVEVLYADYG---NIETLPLCRVQPITSSHLALPFQIIRCSLEGLMELNGSS-SQLI 1071
S + ++ DYG I + ++ + L LP C L G++ G S+
Sbjct: 1952 SPQSLCLVLVDYGFSFYIRYSEIINLKVVPEELLNLPRLSYPCILYGILPAKGKHWSEEA 2011
Query: 1072 IMLLKNFMLNQNVMLSVKGITKNVHTVSVEKCSENGTVDVADKLVTFGLA 1121
+ ++F+ +++ + + V+ E ++AD LV GLA
Sbjct: 2012 KIFFRDFLSKPDLVFQFREYHSET-KLKVDVIHEKN--NLADILVASGLA 2058
Score = 71.6 bits (174), Expect = 4e-12
Identities = 124/590 (21%), Positives = 238/590 (40%), Gaps = 82/590 (13%)
Query: 268 GTVTEFK-----HPGDFYVQLY--SSEVLEYMNQLSASLKETYANVHEKDYIPVKGEVCI 320
GTV E K PGDF QL S ++ M Q+ + Y ++H Y + C+
Sbjct: 901 GTVLEVKCSCYYGPGDFSCQLQCKSEDLKLLMEQI-----QNYYSIHSDPY-EIGQTACV 954
Query: 321 AKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCF 380
AKY+ W RA + + K+ ++++DYG ++ + + + +N L A +C
Sbjct: 955 AKYS--GKWCRAAV--LTQVSKEVDIVFVDYGYQKRVLIEDLCAINPRFLLLESQAFRCC 1010
Query: 381 VANVI-PAEGNWSSDCIKATKPLLMEQYCSIKIVDILEEEVVTFAVEVELPNS-GKLLDH 438
+ + I P S KA + L S ++ + +A+ + PN L+D
Sbjct: 1011 LNHFIEPVSCKLFSWTRKAFRDLWNFISSSRGLLTC-----IIYALVIIHPNHLYNLVD- 1064
Query: 439 VLIEMGYGLKPSGQDSKKENADQSDPEDVGKMTTENNIVVDKSDLIPKVLTLNVGDEFCG 498
L+ S +K+ ++ + + T ++ S + +G E
Sbjct: 1065 --------LQSSFTSAKEFLMNRGSAQYITLSETFPSLFSLYSYCYSS-FNIQIGSEEEV 1115
Query: 499 VVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCD-QLPPRSDFYPAIGDICCAQFSEDDQ 557
++HI +P+ F+CQ ++ + L ++ +++ + Q P+ D +C +++ ED
Sbjct: 1116 YISHIYSPQKFYCQLGRNNKDLEMIETKITESVNLQNFPKYDSNKM--RVCISKYVEDGL 1173
Query: 558 WYRASVLAYASEESVLVGYVDYGNFEILS---LMRLCPIIPKLLELPMQAIKCVLAGVKP 614
YRA + S V +VD+GN +++ L + P+LL PMQAIKC L+ ++
Sbjct: 1174 SYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIKCFLSDLR- 1232
Query: 615 SLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPHVSVSKVLLDAGFAV 674
+ I + + + + + + + +EL D S+ + + +L G
Sbjct: 1233 DVDIPAEISSWFKDNFLGRSLKAIILSQESDGQLGIELYDGSQYINEKIKVLLHAYGKRH 1292
Query: 675 GEQSMVTDKPSDVKETS-VPLGVEGKV----------NPLEWTWVELGVDQTVDVVVCVI 723
+Q+ +K + + E ++GK P T+ E +DQ +
Sbjct: 1293 CDQACCMEKSNKINENKRFTTSLKGKTGNNYRHNVINKPSPVTYSERKIDQ--------L 1344
Query: 724 YSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFFAGDGSWYRAL 783
P + LK K+ ++K+ + L +G K P A
Sbjct: 1345 MHPKNIHARFLKPSVCYKMEPVSKN---KMKTSLNDGLKGIKIVPGAA------------ 1389
Query: 784 VKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADI 833
IL N V +++ V+ +R ++ T P+ IR Q+ D+
Sbjct: 1390 --HILENRR-----VGQKSVKVVSQSFIRALNQTTSQNPYDLIRPQIKDL 1432
>gi|169163210 PREDICTED: similar to tudor domain containing 1 [Homo
sapiens]
Length = 2080
Score = 139 bits (349), Expect = 2e-32
Identities = 199/924 (21%), Positives = 376/924 (40%), Gaps = 125/924 (13%)
Query: 226 DVEVNNKSDCPLGVTKEIAIWAERIMFSDLRSLQLKKTMEIKGTVTEFKHPGDFYVQLYS 285
D+ + + + LG K+ ++ + ++ SL + T +K V+ P FY QL
Sbjct: 352 DLLQHKRPELSLG-NKDTSLDIQHVLDKLQPSLSVGSTESVK--VSSALSPSKFYCQLI- 407
Query: 286 SEVLEYMNQLSASLKETYANVHEKDYIPVK--GEVCIAKYTVDQTWNRAIIQNVDVQQKK 343
+ + L+A + Y V ++ G +C+A+ Q W+R I+Q + + +
Sbjct: 408 -KWTPELENLTAHMTLHYDTVCQETSPTCDNFGLLCVARRRNGQ-WHRGILQQL-LPPNQ 464
Query: 344 AHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCFVANVIPAEGNWSSDCIKATKPLL 403
+ ++DYG+ E IP + L ++ L P + C + + + + + K L
Sbjct: 465 VKIWFMDYGSSEAIPSIYVKKLKQDFILVPLFSFPCSLTCLHSPDRDARIFQLSIFKQAL 524
Query: 404 MEQYCSIKIVDILEEEVVTFAVEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENA-DQS 462
+ Q I D ++ + V ++ S +L +G + DSK N ++
Sbjct: 525 LGQVVYAHI-DWFNKDECLYYVTLQTQESTVNSKCLLKTVGTQVLCPMSDSKISNILSET 583
Query: 463 DPEDVGKMTTEN---NIV-----VDKSDLIP-----KVLTLNVGDEFCGVVAHIQTPEDF 509
DV E+ NI ++K ++ K + + + + +A++ P +F
Sbjct: 584 SVSDVNSFAVESFMGNIEWSIDSLNKKGILKVGFPIKTVQMEIEAAYIAFIAYVLNPSNF 643
Query: 510 FCQQLQSGRKLAELQASLSKYCDQLPPRSDFY--PAIGDICCAQFSEDDQWYRASVLAYA 567
+ + + E+ +++K+ D P G CCA++S+D ++YRA V+
Sbjct: 644 WVRTNDHRNEFQEIMKNINKFYDLCENDEMILRKPEPGLFCCARYSKDRRFYRA-VITEI 702
Query: 568 SEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAGVKPSLGIWTPEAICLM 627
+ + V ++DYGN + + + ++P+ ELP A+ C LA + P +WT AI
Sbjct: 703 NGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSLAHIFPVEDLWTKAAIDYF 762
Query: 628 KKLVQNKIITVKVVDKLENSSLVELIDKSETPHVSVSKVLLDAGFA-------------V 674
KKLV NK I ++V+ K ++ V + + ++ V ++L AG+A V
Sbjct: 763 KKLVLNKAILLQVIAKKDDKYTVNIQSVEASENIDVISLMLQAGYAEYFQVELEYFPKSV 822
Query: 675 GEQSMVTDKPS---DVKET---------------------------SVPLGVEGKVNPL- 703
E SM+ + ++K+ S+ + + NP
Sbjct: 823 SEYSMLNSESKNKVNIKKVISALLEGPKSKKYHSNNLVENNLSLPKSLAVNISEFKNPFT 882
Query: 704 -------EWTWVE--LGVDQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQ 754
W + E ++V Y PG+F C + K DL K L E Q
Sbjct: 883 LSVGPESSWPYKEYIFRPGTVLEVKCSCYYGPGDFSCQL-----QCKSEDL-KLLMEQIQ 936
Query: 755 QKLP-NGFKAEIGQPCCAFFAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRM 813
+ EIGQ C G W RA V + + V + FVDYG + V ++L
Sbjct: 937 NYYSIHSDPYEIGQTACV-AKYSGKWCRAAVLTQV-SKEVDIVFVDYGYQKRVLIEDLCA 994
Query: 814 ISSTFLNLPFQGIRCQL----ADIQSRNKHWSEEAITRFQMCVAGIK-----LQARVVEV 864
I+ FL L Q RC L + + W+ +A ++ + + +V +
Sbjct: 995 INPRFLLLESQAFRCCLNHFIEPVSCKLFSWTRKAFRDLWNFISSSRGLLTCIIYALVII 1054
Query: 865 TENGIGVELTDLSTCYPRIISDVLIDEHLVLKSASPHKDLPNDRLVNKHELQVHVQGLQA 924
N + L DL + + E L+ + ++ + L ++ + L +
Sbjct: 1055 HPNHL-YNLVDLQSSF------TSAKEFLMNRGSAQYITL-SETFPSLFSLYSYC----- 1101
Query: 925 TSSAEQWKTIELPVDKTIQANVLEIISPNLFYALPKGMPENQEKLCMLTAELLEYCNAPK 984
+ + + + + + I SP FY + N + L M+ ++ E N +
Sbjct: 1102 ------YSSFNIQIGSEEEVYISHIYSPQKFYC---QLGRNNKDLEMIETKITESVNL-Q 1151
Query: 985 SRPPYRPRIGDACCAKYTSDDFWYRAVVLGT-SDTDVEVLYADYGNIETLPLCRVQPITS 1043
+ P Y C +KY D YRA+ + T S ++ +V + D+GN + + ++ I++
Sbjct: 1152 NFPKYDSNKMRVCISKYVEDGLSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISA 1211
Query: 1044 SH---LALPFQIIRCSLEGLMELN 1064
L P Q I+C L L +++
Sbjct: 1212 QFPELLFTPMQAIKCFLSDLRDVD 1235
Score = 126 bits (316), Expect = 1e-28
Identities = 162/682 (23%), Positives = 292/682 (42%), Gaps = 103/682 (15%)
Query: 264 MEIKGTVTEF----KHPGDFYVQL--YSSEVLEYMNQLSASLKETYANVHEKDYI----P 313
MEI+ F +P +F+V+ + +E E M ++ + ++ E D + P
Sbjct: 624 MEIEAAYIAFIAYVLNPSNFWVRTNDHRNEFQEIMKNINK-----FYDLCENDEMILRKP 678
Query: 314 VKGEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFP 373
G C A+Y+ D+ + RA+I ++ K +V ++DYGN + IP + L P
Sbjct: 679 EPGLFCCARYSKDRRFYRAVI--TEINGYKINVYFLDYGNTDSIPFFDVKILLPEFCELP 736
Query: 374 PCAIKCFVANVIPAEGNWSSDCIKATKPLLMEQYCSIKIVDILEEEVVTFAVEVELPNSG 433
A+ C +A++ P E W+ I K L++ + ++++ +++ VE +
Sbjct: 737 ALAMCCSLAHIFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQSVEASENI 796
Query: 434 KLLDHVLIEMGYG---------LKPSGQDSKKENADQSDPEDVGKMTT-----------E 473
++ ++++ GY S + N++ + ++ K+ +
Sbjct: 797 DVIS-LMLQAGYAEYFQVELEYFPKSVSEYSMLNSESKNKVNIKKVISALLEGPKSKKYH 855
Query: 474 NNIVVDKSDLIPKVL-----------TLNVGDEFC----------GVVAHIQT-----PE 507
+N +V+ + +PK L TL+VG E G V ++ P
Sbjct: 856 SNNLVENNLSLPKSLAVNISEFKNPFTLSVGPESSWPYKEYIFRPGTVLEVKCSCYYGPG 915
Query: 508 DFFCQQLQSGRKLAELQASLSKYCDQLPPRSDFYPAIGDICCAQFSEDDQWYRASVLAYA 567
DF CQ L L + Y SD Y C A++S +W RA+VL
Sbjct: 916 DFSCQLQCKSEDLKLLMEQIQNYYSI---HSDPYEIGQTACVAKYS--GKWCRAAVLTQV 970
Query: 568 SEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVL----AGVKPSLGIWTPEA 623
S+E +V +VDYG + + + LC I P+ L L QA +C L V L WT +A
Sbjct: 971 SKEVDIV-FVDYGYQKRVLIEDLCAINPRFLLLESQAFRCCLNHFIEPVSCKLFSWTRKA 1029
Query: 624 ICLMKKLVQNK------IITVKVVDKLENSSLVELIDKSETPHVSVSKVLLDAGFAVGEQ 677
+ + + II V+ + + L L+D ++ S + L++ G A
Sbjct: 1030 FRDLWNFISSSRGLLTCIIYALVI--IHPNHLYNLVDL-QSSFTSAKEFLMNRGSA---- 1082
Query: 678 SMVTDKPSDVKETSVPLGVEGKVNPLEWTWVELGVDQTVDVVVCVIYSPGEFYCHVLKED 737
+T + S+ N +++G ++ +V + IYSP +FYC + + +
Sbjct: 1083 QYITLSETFPSLFSLYSYCYSSFN------IQIGSEE--EVYISHIYSPQKFYCQLGRNN 1134
Query: 738 ALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFFAGDGSWYRALVKEILPNGHVKVHF 797
K L + + E + + + + C + + DG YRAL + +V+F
Sbjct: 1135 --KDLEMIETKITESVNLQNFPKYDSNKMRVCISKYVEDGLSYRALAIPTDSSSEFQVYF 1192
Query: 798 VDYGNIEEVTADELRMISSTFLNL---PFQGIRCQLADIQSRNKHWSEEAITRFQMCVAG 854
VD+GN + V + LR IS+ F L P Q I+C L+D+ R+ E + F+ G
Sbjct: 1193 VDFGNKQLVGENMLRAISAQFPELLFTPMQAIKCFLSDL--RDVDIPAEISSWFKDNFLG 1250
Query: 855 IKLQARVVEVTENG-IGVELTD 875
L+A ++ +G +G+EL D
Sbjct: 1251 RSLKAIILSQESDGQLGIELYD 1272
Score = 115 bits (289), Expect = 2e-25
Identities = 129/649 (19%), Positives = 263/649 (40%), Gaps = 70/649 (10%)
Query: 544 IGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQ 603
I + C + +W R V+ +E ++ +D G ++ ++ L ELP +
Sbjct: 208 IDEFCLVEERVSGEWQRGRVMEKKNELYTVL-LIDRGEELRVAGPQIASACGNLFELPPR 266
Query: 604 AIKCVLAGVKPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPHVSV 663
+ + A + P W+P+A+ K LV ++V ++ +++ E P +
Sbjct: 267 VVFGIFANILPVGEKWSPKALNYFKSLVG-----IQVKGYVQAILPLQMF-LFEVPKIIS 320
Query: 664 SKVLLDAGFAVGEQS------MVTDKPSDV---------------KETSVPLG-VEGKVN 701
+ L G V S M+ + P + K+TS+ + V K+
Sbjct: 321 QALELQLGRLVDGDSFRLIVEMLEEFPQQMPDLLQHKRPELSLGNKDTSLDIQHVLDKLQ 380
Query: 702 PLEWTWVELGVDQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEH----CQQKL 757
P L V T V V SP +FYC ++K +L +L + H CQ+
Sbjct: 381 P------SLSVGSTESVKVSSALSPSKFYCQLIKWTP--ELENLTAHMTLHYDTVCQETS 432
Query: 758 PNGFKAEIGQPCCAFFAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISST 817
P + C +G W+R +++++LP VK+ F+DYG+ E + + ++ +
Sbjct: 433 PTCDNFGL---LCVARRRNGQWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQD 489
Query: 818 FLNLPFQGIRCQLADIQSRNKHWSEEAITRFQMCVAGIKLQARV-------------VEV 864
F+ +P C L + S ++ ++ F+ + G + A + ++
Sbjct: 490 FILVPLFSFPCSLTCLHSPDRDARIFQLSIFKQALLGQVVYAHIDWFNKDECLYYVTLQT 549
Query: 865 TENGIGVE--LTDLSTCYPRIISDVLIDEHLVLKSASPHKDLPNDRLVNKHELQVHVQGL 922
E+ + + L + T +SD I L S S + + E +
Sbjct: 550 QESTVNSKCLLKTVGTQVLCPMSDSKISNILSETSVSDVNSFAVESFMGNIEWSIDSLNK 609
Query: 923 QATSSAE-QWKTIELPVDKTIQANVLEIISPNLFYALPKGMPENQEKLCMLTAELLEYCN 981
+ KT+++ ++ A + +++P+ F+ +++ + + C
Sbjct: 610 KGILKVGFPIKTVQMEIEAAYIAFIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCE 669
Query: 982 APKSRPPYRPRIGDACCAKYTSDDFWYRAVVLGTSDTDVEVLYADYGNIETLPLCRVQPI 1041
+ +P G CCA+Y+ D +YRAV+ + + V + DYGN +++P V+ +
Sbjct: 670 NDEMILR-KPEPGLFCCARYSKDRRFYRAVITEINGYKINVYFLDYGNTDSIPFFDVKIL 728
Query: 1042 TSSHLALPFQIIRCSLEGLMELNGSSSQLIIMLLKNFMLNQNVMLSVKGITKNVHTVSVE 1101
LP + CSL + + ++ I K +LN+ ++L V + +TV+++
Sbjct: 729 LPEFCELPALAMCCSLAHIFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQ 788
Query: 1102 KCSENGTVDVADKLVTFGLAKNITPQRQ---------SALNTEKMYRMN 1141
+ +DV ++ G A+ + + S LN+E ++N
Sbjct: 789 SVEASENIDVISLMLQAGYAEYFQVELEYFPKSVSEYSMLNSESKNKVN 837
Score = 112 bits (281), Expect = 2e-24
Identities = 187/905 (20%), Positives = 355/905 (39%), Gaps = 122/905 (13%)
Query: 317 EVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCA 376
E C+ + V W R + ++ + + VL ID G E + +I N+ PP
Sbjct: 210 EFCLVEERVSGEWQRGRV--MEKKNELYTVLLIDRGEELRVAGPQIASACGNLFELPPRV 267
Query: 377 IKCFVANVIPAEGNWSSDCIKATKPLL-------MEQYCSIKIVDILEEEVVTFAVEVEL 429
+ AN++P WS + K L+ ++ +++ ++++ A+E++L
Sbjct: 268 VFGIFANILPVGEKWSPKALNYFKSLVGIQVKGYVQAILPLQMFLFEVPKIISQALELQL 327
Query: 430 PNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPE-DVGKMTTENNI--VVDKSDLIPK 486
G+L+D + + + PE +G T +I V+DK L P
Sbjct: 328 ---GRLVDGDSFRLIVEMLEEFPQQMPDLLQHKRPELSLGNKDTSLDIQHVLDK--LQP- 381
Query: 487 VLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSKY----CDQLPPRSDFYP 542
+L+VG V+ +P F+CQ ++ +L L A ++ + C + P D +
Sbjct: 382 --SLSVGSTESVKVSSALSPSKFYCQLIKWTPELENLTAHMTLHYDTVCQETSPTCDNF- 438
Query: 543 AIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPM 602
G +C A+ + QW+R + V + ++DYG+ E + + + + + +P+
Sbjct: 439 --GLLCVAR-RRNGQWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILVPL 495
Query: 603 QAIKCVLAGVKPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPHVS 662
+ C L + + + K+ + +++ + D + +
Sbjct: 496 FSFPCSLTCLHSPDRDARIFQLSIFKQALLGQVVYAHI-DWFNKDECLYYVTLQTQESTV 554
Query: 663 VSKVLLDAGFAVGEQSMVTDKPSDVK----ETSVP----LGVEGKVNPLEWT-------- 706
SK LL VG Q + S + ETSV VE + +EW+
Sbjct: 555 NSKCLLKT---VGTQVLCPMSDSKISNILSETSVSDVNSFAVESFMGNIEWSIDSLNKKG 611
Query: 707 ---------WVELGVDQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEH---CQ 754
V++ ++ + + +P F+ V D + ++ K++ + C+
Sbjct: 612 ILKVGFPIKTVQMEIEAAYIAFIAYVLNPSNFW--VRTNDHRNEFQEIMKNINKFYDLCE 669
Query: 755 QKLPNGFKAEIGQPCCAFFAGDGSWYRALVKEILPNGH-VKVHFVDYGNIEEVTADELRM 813
K E G CCA ++ D +YRA++ EI NG+ + V+F+DYGN + + ++++
Sbjct: 670 NDEMILRKPEPGLFCCARYSKDRRFYRAVITEI--NGYKINVYFLDYGNTDSIPFFDVKI 727
Query: 814 ISSTFLNLPFQGIRCQLADIQSRNKHWSEEAITRFQMCVAGIKLQARVVEVTENGIGVEL 873
+ F LP + C LA I W++ AI F+ V + +V+ ++ V +
Sbjct: 728 LLPEFCELPALAMCCSLAHIFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNI 787
Query: 874 TDLSTCYP-RIISDVL---------IDEHLVLKSASPHKDLPNDRLVNKHELQVHVQGLQ 923
+ +IS +L ++ KS S + L N NK ++ + L
Sbjct: 788 QSVEASENIDVISLMLQAGYAEYFQVELEYFPKSVSEYSML-NSESKNKVNIKKVISALL 846
Query: 924 ATSSAEQWKT-----IELPVDKTIQANVLEIISPNLFYALPKG----------------- 961
++++ + L + K++ N+ E +P P+
Sbjct: 847 EGPKSKKYHSNNLVENNLSLPKSLAVNISEFKNPFTLSVGPESSWPYKEYIFRPGTVLEV 906
Query: 962 --------------MPENQEKLCMLTAELLEYCNAPKSRPPYRPRIGD-ACCAKYTSDDF 1006
+ E L +L ++ Y + PY IG AC AKY+
Sbjct: 907 KCSCYYGPGDFSCQLQCKSEDLKLLMEQIQNYYSIHSD--PY--EIGQTACVAKYSGK-- 960
Query: 1007 WYRAVVLGTSDTDVEVLYADYGNIETLPLCRVQPITSSHLALPFQIIRCSLEGLMELNGS 1066
W RA VL +V++++ DYG + + + + I L L Q RC L +E
Sbjct: 961 WCRAAVLTQVSKEVDIVFVDYGYQKRVLIEDLCAINPRFLLLESQAFRCCLNHFIE--PV 1018
Query: 1067 SSQLIIMLLKNFMLNQNVMLSVKGITKNVHTVSVEKCSENGTVDVADKLVTFGLAKNITP 1126
S +L K F N + S +G+ + ++ N ++ D +F AK
Sbjct: 1019 SCKLFSWTRKAFRDLWNFISSSRGLLTCI-IYALVIIHPNHLYNLVDLQSSFTSAKEFLM 1077
Query: 1127 QRQSA 1131
R SA
Sbjct: 1078 NRGSA 1082
Score = 105 bits (262), Expect = 3e-22
Identities = 145/626 (23%), Positives = 261/626 (41%), Gaps = 70/626 (11%)
Query: 249 RIMFSDLRSLQLKKTMEIKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASLKETYANVHE 308
R DL Q+ ++KG V+ +P +F++QL +E + + +L+ +L T + E
Sbjct: 1426 RPQIKDLPQPQIYLNAKVKGYVSNISNPANFHIQLAENESV--IIRLADALNATARRLRE 1483
Query: 309 KDYI-PVKGEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNR 367
+ + P+ G++ +A+Y+ D RA+I+ + + V +IDYGN I+ ++IY L R
Sbjct: 1484 RKSVKPLVGDLVVAEYSGDNAIYRAVIKKI-LPGNSFEVEFIDYGNSAIVNTSKIYELQR 1542
Query: 368 NIDLFPPCAIKCFVANVIPAEGN--WSSDCIK--ATKPLLMEQYCSI--------KIVDI 415
P I F++ V E + W + +K YC ++ I
Sbjct: 1543 EFLTVPQLGIHAFLSGVKWNEPDEIWDDKTVDYFTSKVHNKTVYCEFLKKHDQKWEVNMI 1602
Query: 416 LEE-----EVVTFAVEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPEDVGKM 470
+E E++ + +L S + VL + ++P + KK +++S+ G M
Sbjct: 1603 CDEKCVINELLKWKACSKLQKSALQMPQVLSQK---VRPGDNEMKKGKSNESE----GSM 1655
Query: 471 TTENNIVVDKSDLIPKVLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSKY 530
+ + IP + +G + ++ F+ + ++ + L++L ++K
Sbjct: 1656 NSNQQLF-----KIP-LEEFKLGQLEKAEMLNVSKSGRFYVKLSKNKKILSDLIVLITKE 1709
Query: 531 CDQLPPRSDFYPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRL 590
+ P S G C A+ +W+R+ V ++ VLV VD G +EI+ +
Sbjct: 1710 EKKSPFLSMESIEKGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCGIYEIVPVCNT 1769
Query: 591 CPIIPKLLELPMQAIKCVLAGVKPSLGIWTPEAICLMKKLVQNKIITVKVVDK------- 643
+ ++ +P QA+ C + S I CL L N I+ +K +D
Sbjct: 1770 KLLSNEIRNIPRQAVPCKWIWFENSKNI---SFECLFADLEIN-ILFLKYLDAVWEVEIL 1825
Query: 644 LENSSLVELIDKSETPHVSVSKVLLDAGFAVGEQSMVTDKPSDVKETSVPLGVEGKVNPL 703
+++ L+E ++ + P V +K+ L A +S +K
Sbjct: 1826 VDDLLLLEYLNLNTVP-VEENKLRL-AEIVYNIESKTPVSSCTIK--------------- 1868
Query: 704 EWTWVELGVDQTVDVVVCVIYSPGEFYCHVLK-EDALKKLNDLNKSLAEHCQQKLPNGFK 762
+TWV+ D+ + + P +F + D +K L L L E Q LP F
Sbjct: 1869 SFTWVQFQNDRQYSGIATAVSDPSDFSIQLEDFFDIMKYLFMLLSDLPE-TLQTLPQEFI 1927
Query: 763 AEIGQPCCAFFAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADE---LRMISSTFL 819
G C + + W R + E+ P V VDYG + E L+++ L
Sbjct: 1928 IP-GSSCLFKYKSEDQWNRVEISEVSPQSLCLV-LVDYGFSFYIRYSEIINLKVVPEELL 1985
Query: 820 NLPFQGIRCQLADI-QSRNKHWSEEA 844
NLP C L I ++ KHWSEEA
Sbjct: 1986 NLPRLSYPCILYGILPAKGKHWSEEA 2011
Score = 96.3 bits (238), Expect = 2e-19
Identities = 137/650 (21%), Positives = 257/650 (39%), Gaps = 62/650 (9%)
Query: 498 GVVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDFYPAIGDICCAQFSEDDQ 557
G V++I P +F Q ++ + L +L+ +L R P +GD+ A++S D+
Sbjct: 1445 GYVSNISNPANFHIQLAENESVIIRLADALNATARRLRERKSVKPLVGDLVVAEYSGDNA 1504
Query: 558 WYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAGVK--PS 615
YRA + S V ++DYGN I++ ++ + + L +P I L+GVK
Sbjct: 1505 IYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKIYELQREFLTVPQLGIHAFLSGVKWNEP 1564
Query: 616 LGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELI----------------DKSETP 659
IW + + V NK + + + K + V +I K +
Sbjct: 1565 DEIWDDKTVDYFTSKVHNKTVYCEFLKKHDQKWEVNMICDEKCVINELLKWKACSKLQKS 1624
Query: 660 HVSVSKVLLDAGFAVGEQSMVTDKPSDVKETSVPLGVEGKVNPLEWTWVELGVDQTVDVV 719
+ + +V L G+ M K S+ E S+ + PLE E + Q
Sbjct: 1625 ALQMPQV-LSQKVRPGDNEMKKGK-SNESEGSMNSNQQLFKIPLE----EFKLGQLEKAE 1678
Query: 720 VCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLP--NGFKAEIGQPCCAFFAGDG 777
+ + G FY + K K L+DL + + ++K P + E G C A
Sbjct: 1679 MLNVSKSGRFYVKLSKNK--KILSDLIVLITKE-EKKSPFLSMESIEKGLECLAKSKNTL 1735
Query: 778 SWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQSRN 837
W+R+ V+E + V V VD G E V +++S+ N+P Q + C+ ++
Sbjct: 1736 KWHRSKVEEKYVDDKVLVFLVDCGIYEIVPVCNTKLLSNEIRNIPRQAVPCKWIWFENSK 1795
Query: 838 KHWSEEAITRFQMCVAGIKLQARVVEVTENGIGVELTDLSTCYPRIISDVLIDEHLVLKS 897
E ++ + +K V EV ++L+D+ L+L+
Sbjct: 1796 NISFECLFADLEINILFLKYLDAVWEV---------------------EILVDDLLLLEY 1834
Query: 898 ASPHKDLPNDRLVNKHELQVHVQGLQATSSA--EQWKTIELPVDKTIQANVLEIISPNLF 955
+ + + + E+ +++ SS + + ++ D+ + P+ F
Sbjct: 1835 LNLNTVPVEENKLRLAEIVYNIESKTPVSSCTIKSFTWVQFQNDRQYSGIATAVSDPSDF 1894
Query: 956 YALPKGMPENQEKLCMLTAELLEYCNAPKSRPPYRPRIGDACCAKYTSDDFWYRAVVLGT 1015
+ + + L ML ++L E ++ P G +C KY S+D W R +
Sbjct: 1895 SIQLEDFFDIMKYLFMLLSDLPE---TLQTLPQEFIIPGSSCLFKYKSEDQWNRVEISEV 1951
Query: 1016 SDTDVEVLYADYG---NIETLPLCRVQPITSSHLALPFQIIRCSLEGLMELNGSS-SQLI 1071
S + ++ DYG I + ++ + L LP C L G++ G S+
Sbjct: 1952 SPQSLCLVLVDYGFSFYIRYSEIINLKVVPEELLNLPRLSYPCILYGILPAKGKHWSEEA 2011
Query: 1072 IMLLKNFMLNQNVMLSVKGITKNVHTVSVEKCSENGTVDVADKLVTFGLA 1121
+ ++F+ +++ + + V+ E ++AD LV GLA
Sbjct: 2012 KIFFRDFLSKPDLVFQFREYHSET-KLKVDVIHEKN--NLADILVASGLA 2058
Score = 71.6 bits (174), Expect = 4e-12
Identities = 124/590 (21%), Positives = 238/590 (40%), Gaps = 82/590 (13%)
Query: 268 GTVTEFK-----HPGDFYVQLY--SSEVLEYMNQLSASLKETYANVHEKDYIPVKGEVCI 320
GTV E K PGDF QL S ++ M Q+ + Y ++H Y + C+
Sbjct: 901 GTVLEVKCSCYYGPGDFSCQLQCKSEDLKLLMEQI-----QNYYSIHSDPY-EIGQTACV 954
Query: 321 AKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCF 380
AKY+ W RA + + K+ ++++DYG ++ + + + +N L A +C
Sbjct: 955 AKYS--GKWCRAAV--LTQVSKEVDIVFVDYGYQKRVLIEDLCAINPRFLLLESQAFRCC 1010
Query: 381 VANVI-PAEGNWSSDCIKATKPLLMEQYCSIKIVDILEEEVVTFAVEVELPNS-GKLLDH 438
+ + I P S KA + L S ++ + +A+ + PN L+D
Sbjct: 1011 LNHFIEPVSCKLFSWTRKAFRDLWNFISSSRGLLTC-----IIYALVIIHPNHLYNLVD- 1064
Query: 439 VLIEMGYGLKPSGQDSKKENADQSDPEDVGKMTTENNIVVDKSDLIPKVLTLNVGDEFCG 498
L+ S +K+ ++ + + T ++ S + +G E
Sbjct: 1065 --------LQSSFTSAKEFLMNRGSAQYITLSETFPSLFSLYSYCYSS-FNIQIGSEEEV 1115
Query: 499 VVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCD-QLPPRSDFYPAIGDICCAQFSEDDQ 557
++HI +P+ F+CQ ++ + L ++ +++ + Q P+ D +C +++ ED
Sbjct: 1116 YISHIYSPQKFYCQLGRNNKDLEMIETKITESVNLQNFPKYDSNKM--RVCISKYVEDGL 1173
Query: 558 WYRASVLAYASEESVLVGYVDYGNFEILS---LMRLCPIIPKLLELPMQAIKCVLAGVKP 614
YRA + S V +VD+GN +++ L + P+LL PMQAIKC L+ ++
Sbjct: 1174 SYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIKCFLSDLR- 1232
Query: 615 SLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPHVSVSKVLLDAGFAV 674
+ I + + + + + + + +EL D S+ + + +L G
Sbjct: 1233 DVDIPAEISSWFKDNFLGRSLKAIILSQESDGQLGIELYDGSQYINEKIKVLLHAYGKRH 1292
Query: 675 GEQSMVTDKPSDVKETS-VPLGVEGKV----------NPLEWTWVELGVDQTVDVVVCVI 723
+Q+ +K + + E ++GK P T+ E +DQ +
Sbjct: 1293 CDQACCMEKSNKINENKRFTTSLKGKTGNNYRHNVINKPSPVTYSERKIDQ--------L 1344
Query: 724 YSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFFAGDGSWYRAL 783
P + LK K+ ++K+ + L +G K P A
Sbjct: 1345 MHPKNIHARFLKPSVCYKMEPVSKN---KMKTSLNDGLKGIKIVPGAA------------ 1389
Query: 784 VKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADI 833
IL N V +++ V+ +R ++ T P+ IR Q+ D+
Sbjct: 1390 --HILENRR-----VGQKSVKVVSQSFIRALNQTTSQNPYDLIRPQIKDL 1432
>gi|58197558 tudor domain containing 6 [Homo sapiens]
Length = 2096
Score = 134 bits (338), Expect = 4e-31
Identities = 172/696 (24%), Positives = 292/696 (41%), Gaps = 106/696 (15%)
Query: 248 ERIMFSDLRSLQLKKTMEIKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASLKETYANVH 307
E I LRS++LK V K+P +F+++L V ++L + Y++
Sbjct: 471 EEISLPALRSIRLKMNAFYDAQVEFVKNPSEFWIRLRKHNVT--FSKLMRRMCGFYSSAS 528
Query: 308 EKDYIPVKGE---VCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYH 364
+ D + +K E +C K+ + + RAI+ +D K V +D GN E + +
Sbjct: 529 KLDGVVLKPEPDDLCCVKWK-ENGYYRAIVTKLD--DKSVDVFLVDRGNSENVDWYDVRM 585
Query: 365 LNRNIDLFPPCAIKCFVANVIPAEGNWSSDCIKATKPLLMEQYCSIKIVD---------I 415
L P A+KC +A++ P WS + + K ++ + I I+D I
Sbjct: 586 LLPQFRQLPILAVKCTLADIWPLGKTWSQEAVSFFKKTVLHKELVIHILDKQDHQYVIEI 645
Query: 416 LEE---------EVVTFA-------------VEVELPNSGKLLDHVLIEMG---YGLKPS 450
L+E +V+ A + V + G + +H E +
Sbjct: 646 LDESRTGEENISKVIAQAGYAKYQEFETKENILVNAHSPGHVSNHFTTESNKIPFAKTGE 705
Query: 451 G-QDSKKENADQSDPEDVGKMTTENN----IVVDKS--------DLIPKVLTLNVGDEFC 497
G Q +K+EN S + + T N +VV + L+ L + G
Sbjct: 706 GEQKAKRENKTTSVSKALSDTTVVTNGSTELVVQEKVKRASVYFPLMQNCLEIKPGSSSK 765
Query: 498 GV----------VAHIQTPEDFFCQQLQSGRKLAELQASLSKYC-DQLPPRSDFYPAIGD 546
G V++++ P F+CQ ++ + L L + + YC + P A
Sbjct: 766 GELEVGSTVEVRVSYVENPGYFWCQLTRNIQGLKTLMSDIQYYCKNTAAPHQRNTLA--- 822
Query: 547 ICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIK 606
C A+ + + QW RA + S E V V +VDYG+ E++S+ + I + L++ QA +
Sbjct: 823 -CLAKRTVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQAFR 881
Query: 607 CVLAGVKPSLG----IWTPEAICLMKKLVQN---KIITVK-VVDKLE--NSSLVELIDKS 656
C L + +G +W +AI + + N K + +K + L N L ++D
Sbjct: 882 CSLYNLIQPVGQNPFVWDVKAIQAFNEFIDNAWQKNLELKCTIFALASINEELFNIVDLL 941
Query: 657 ETPHVSVSKVLLDAGFAVGEQSMVTDKPSDVKETSVPLGVEGKVNPLEWTWVELGVDQTV 716
TP S L++ A +P +++ PL +++ ++ ++ +
Sbjct: 942 -TPFQSACHFLVEKRLA---------RPVKLQK---PLESSVQLHSYFYSTHDMKIGSEE 988
Query: 717 DVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLP-NGFKAEIGQPCCAFFAG 775
V + I P FYC + + + L L+ S+ + + L G C A +
Sbjct: 989 LVYITHIDDPWTFYCQLARNANI--LEQLSCSITQLSKVLLNLKTSPLNPGTLCLAKYT- 1045
Query: 776 DGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISS---TFLNLPFQGIRCQLAD 832
DG+WYR +V E P KV FVD+GNI VT+D+L I S L LP Q +RC L+D
Sbjct: 1046 DGNWYRGIVIEKEPK---KVFFVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQAVRCSLSD 1102
Query: 833 IQSRNKHWSEEAITRFQMCVAGIKLQARVVEVTENG 868
I H EE + FQ + L+A VV +G
Sbjct: 1103 IPD---HIPEEVVVWFQETILDKSLKALVVAKDPDG 1135
Score = 115 bits (288), Expect = 2e-25
Identities = 99/434 (22%), Positives = 196/434 (45%), Gaps = 31/434 (7%)
Query: 258 LQLKKTMEIKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASLKETY-------------A 304
LQL T + +T+ HP + QL S V + +++LS S+ + Y A
Sbjct: 246 LQLGVTEAV--VITQVCHPHRIHCQLRS--VSQEIHRLSESMAQVYRGSTGTGDENSTSA 301
Query: 305 NVHEKDYIPVKGEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYH 364
E++ P K A +D W RA++ Q+ A VL++DYG +E++ + + +
Sbjct: 302 TWEEREESPDKPGSPCASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRY 361
Query: 365 LNRNIDLFPPCAIKCFVANVIPAEGNWSSDCIKATKPLLMEQYCSIKIVDILEEEVVTFA 424
L P C + + WS + K L++ + + KI E V +
Sbjct: 362 LLPEYFRMPVVTYPCALYGLWDGGRGWSRSQVGDLKTLILGKAVNAKIEFYCSFEHVYY- 420
Query: 425 VEVELPNSGKLLDHVLIEMGYGLKP---SGQDSKKENADQSDPEDVGKMTTENNIVVDKS 481
V L D + + +G++ + + + + ++ +PE + + + S
Sbjct: 421 --VSLYGE----DGINLNRVFGVQSCCLADRVLQSQATEEEEPETSQSQSPAEEVDEEIS 474
Query: 482 DLIPKVLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDFY 541
+ + L + + V ++ P +F+ + + ++L + +
Sbjct: 475 LPALRSIRLKMNAFYDAQVEFVKNPSEFWIRLRKHNVTFSKLMRRMCGFYSSASKLDGVV 534
Query: 542 --PAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLE 599
P D+CC ++ E+ +YRA ++ ++SV V VD GN E + + ++P+ +
Sbjct: 535 LKPEPDDLCCVKWKENG-YYRA-IVTKLDDKSVDVFLVDRGNSENVDWYDVRMLLPQFRQ 592
Query: 600 LPMQAIKCVLAGVKPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETP 659
LP+ A+KC LA + P W+ EA+ KK V +K + + ++DK ++ ++E++D+S T
Sbjct: 593 LPILAVKCTLADIWPLGKTWSQEAVSFFKKTVLHKELVIHILDKQDHQYVIEILDESRTG 652
Query: 660 HVSVSKVLLDAGFA 673
++SKV+ AG+A
Sbjct: 653 EENISKVIAQAGYA 666
Score = 112 bits (280), Expect = 2e-24
Identities = 136/585 (23%), Positives = 235/585 (40%), Gaps = 73/585 (12%)
Query: 549 CAQFSEDDQWYRASVL-AYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKC 607
CA D WYRA +L + + V +VDYG E++S L ++P+ +P+ C
Sbjct: 317 CASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEYFRMPVVTYPC 376
Query: 608 VLAGVKPSLGIWTPEAICLMKKLVQNKIITVKV--VDKLENSSLVELI--DKSETPHVSV 663
L G+ W+ + +K L+ K + K+ E+ V L D V
Sbjct: 377 ALYGLWDGGRGWSRSQVGDLKTLILGKAVNAKIEFYCSFEHVYYVSLYGEDGINLNRVFG 436
Query: 664 SKVLLDAGFAVGEQSMVTDKPSDVKETSVPLGVEGKVNPLEWTWVELGVDQTVDVVVCVI 723
+ A + Q+ ++P + S V+ +++ + L ++ D V +
Sbjct: 437 VQSCCLADRVLQSQATEEEEPETSQSQSPAEEVDEEISLPALRSIRLKMNAFYDAQVEFV 496
Query: 724 YSPGEFYCHVLKEDA-LKKLNDLNKSLAEHCQQKLPNG--FKAEIGQPCCAFFAGDGSWY 780
+P EF+ + K + KL + + + +G K E CC + +G +Y
Sbjct: 497 KNPSEFWIRLRKHNVTFSKL--MRRMCGFYSSASKLDGVVLKPEPDDLCCVKWKENG-YY 553
Query: 781 RALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQSRNKHW 840
RA+V + L + V V VD GN E V ++RM+ F LP ++C LADI K W
Sbjct: 554 RAIVTK-LDDKSVDVFLVDRGNSENVDWYDVRMLLPQFRQLPILAVKCTLADIWPLGKTW 612
Query: 841 SEEAITRFQMCVAGIKLQARVVEVTENGIGVELTDLSTCYPRIISDVLID---------- 890
S+EA++ F+ V +L +++ ++ +E+ D S IS V+
Sbjct: 613 SQEAVSFFKKTVLHKELVIHILDKQDHQYVIEILDESRTGEENISKVIAQAGYAKYQEFE 672
Query: 891 --EHLVLKSASP-----HKDLPNDRL--------------------VNKHELQVHVQGLQ 923
E++++ + SP H ++++ V+K V
Sbjct: 673 TKENILVNAHSPGHVSNHFTTESNKIPFAKTGEGEQKAKRENKTTSVSKALSDTTVVTNG 732
Query: 924 ATSSAEQWKTIELPVDKTIQANVLEI---------------ISPNLFYALPKG-----MP 963
+T Q K V + N LEI + + Y G +
Sbjct: 733 STELVVQEKVKRASVYFPLMQNCLEIKPGSSSKGELEVGSTVEVRVSYVENPGYFWCQLT 792
Query: 964 ENQEKLCMLTAELLEYCNAPKSRPPYRPRIGDACCAKYTSDDFWYRAVVLGTSDTD-VEV 1022
N + L L +++ YC K+ R AC AK T + W RA++ G + V V
Sbjct: 793 RNIQGLKTLMSDIQYYC---KNTAAPHQRNTLACLAKRTVNRQWSRALISGIQSVEHVNV 849
Query: 1023 LYADYGNIETLPLCRVQPITSSHLALPFQIIRCSLEGLMELNGSS 1067
+ DYG+ E + + + I+ L + Q RCSL L++ G +
Sbjct: 850 TFVDYGDREMVSVKNIYSISEEFLKVKAQAFRCSLYNLIQPVGQN 894
Score = 98.2 bits (243), Expect = 4e-20
Identities = 131/623 (21%), Positives = 252/623 (40%), Gaps = 70/623 (11%)
Query: 545 GDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQA 604
G++C Q W+R V++ ++ES V +D G L P + LP +
Sbjct: 70 GELCLVQVGL--LWHRCRVVSRQAQES-RVFLLDEGRTITAGAGSLAPGRREFFNLPSEV 126
Query: 605 IKCVLAGVKPS-LGI--------WTPEAI-------------CLMKKLVQNKIITVKVVD 642
+ CVLAG+ P+ G W +A+ C++ L+ ++++ ++V D
Sbjct: 127 LGCVLAGLVPAGCGAGSGEPPQHWPADAVDFLSNLQGKEVHGCVLDVLLLHRLVLLEVPD 186
Query: 643 KLENSSLVELIDKSETPHVSVSKVLLDAGFAVGEQSMVTDKPSDVKETSVPLGVEGKVNP 702
+ + L + S+ + LL+ S+ + P + VPL + K
Sbjct: 187 VFQQMRELGLARRVPD---SLFRSLLERYLTAATASVGSGVPV---LSRVPL--KQKQPG 238
Query: 703 LEWTWVELGVDQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFK 762
L++ + +L + T VV+ + P +C + ++++ L++S+A+ + G +
Sbjct: 239 LDYFYPQLQLGVTEAVVITQVCHPHRIHCQL--RSVSQEIHRLSESMAQVYRGSTGTGDE 296
Query: 763 AEI--------------GQPCCAFFAGDGSWYRALVKEIL-PNGHVKVHFVDYGNIEEVT 807
G PC A DG WYRAL+ E P +V VDYG E V+
Sbjct: 297 NSTSATWEEREESPDKPGSPC-ASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVS 355
Query: 808 ADELRMISSTFLNLPFQGIRCQLADIQSRNKHWSEEAITRFQMCVAGIKLQARVVEVTE- 866
LR + + +P C L + + WS + + + G + A++
Sbjct: 356 CSSLRYLLPEYFRMPVVTYPCALYGLWDGGRGWSRSQVGDLKTLILGKAVNAKIEFYCSF 415
Query: 867 ------NGIGVELTDLSTCYPRIISDVLIDEHLVLKSASPHKDLPNDRLVNKHELQVHVQ 920
+ G + +L+ + + S L D VL+S + ++ P + Q +
Sbjct: 416 EHVYYVSLYGEDGINLNRVF-GVQSCCLADR--VLQSQATEEEEP-----ETSQSQSPAE 467
Query: 921 GLQATSSAEQWKTIELPVDKTIQANVLEIISPNLFYALPKGMPENQEKLCMLTAELLEYC 980
+ S ++I L ++ A V + +P+ F+ + KL Y
Sbjct: 468 EVDEEISLPALRSIRLKMNAFYDAQVEFVKNPSEFWIRLRKHNVTFSKLMRRMCGF--YS 525
Query: 981 NAPK-SRPPYRPRIGDACCAKYTSDDFWYRAVVLGTSDTDVEVLYADYGNIETLPLCRVQ 1039
+A K +P D CC K+ ++ +YRA+V D V+V D GN E + V+
Sbjct: 526 SASKLDGVVLKPEPDDLCCVKW-KENGYYRAIVTKLDDKSVDVFLVDRGNSENVDWYDVR 584
Query: 1040 PITSSHLALPFQIIRCSLEGLMELNGSSSQLIIMLLKNFMLNQNVMLSVKGITKNVHTVS 1099
+ LP ++C+L + L + SQ + K +L++ +++ + + + +
Sbjct: 585 MLLPQFRQLPILAVKCTLADIWPLGKTWSQEAVSFFKKTVLHKELVIHILDKQDHQYVIE 644
Query: 1100 VEKCSENGTVDVADKLVTFGLAK 1122
+ S G +++ + G AK
Sbjct: 645 ILDESRTGEENISKVIAQAGYAK 667
Score = 95.5 bits (236), Expect = 3e-19
Identities = 100/427 (23%), Positives = 188/427 (44%), Gaps = 55/427 (12%)
Query: 258 LQLKKTMEIKGTVTEFKHPGDFYVQLYSS--EVLEYMNQLSASLKETYANVHEKDYIPVK 315
L++ T+E++ V+ ++PG F+ QL + + M+ + K T A H+++ +
Sbjct: 768 LEVGSTVEVR--VSYVENPGYFWCQLTRNIQGLKTLMSDIQYYCKNTAAP-HQRNTL--- 821
Query: 316 GEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPC 375
C+AK TV++ W+RA+I + + +V ++DYG+ E++ + IY ++
Sbjct: 822 --ACLAKRTVNRQWSRALISGIQ-SVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQ 878
Query: 376 AIKCFVANVIPAEGN----WSSDCIKATKPLL-------MEQYCSIKIVDILEEEVVTFA 424
A +C + N+I G W I+A + +E C+I + + EE+
Sbjct: 879 AFRCSLYNLIQPVGQNPFVWDVKAIQAFNEFIDNAWQKNLELKCTIFALASINEELFNI- 937
Query: 425 VEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPEDVGKMTTENNIVVDKSDLI 484
V+L + H L+E K + K + +S V
Sbjct: 938 --VDLLTPFQSACHFLVE-----KRLARPVKLQKPLESS--------------VQLHSYF 976
Query: 485 PKVLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDFYPAI 544
+ +G E + HI P F+CQ ++ L +L S+++ L
Sbjct: 977 YSTHDMKIGSEELVYITHIDDPWTFYCQLARNANILEQLSCSITQLSKVLLNLKTSPLNP 1036
Query: 545 GDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPI---IPKLLELP 601
G +C A+++ D WYR V+ +E V +VD+GN +++ L PI +L LP
Sbjct: 1037 GTLCLAKYT-DGNWYRGIVI---EKEPKKVFFVDFGNIYVVTSDDLLPIPSDAYDVLLLP 1092
Query: 602 MQAIKCVLAGVKPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSL-VELIDKSETPH 660
MQA++C L+ + + E + ++ + +K + VV K + +L +EL +
Sbjct: 1093 MQAVRCSLSDIPDHI---PEEVVVWFQETILDKSLKALVVAKDPDGTLIIELYGDNIQIS 1149
Query: 661 VSVSKVL 667
S++K L
Sbjct: 1150 ASINKKL 1156
Score = 92.8 bits (229), Expect = 2e-18
Identities = 98/418 (23%), Positives = 178/418 (42%), Gaps = 23/418 (5%)
Query: 500 VAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDFY--PAI--GDICCAQFSED 555
V+HI DF+ Q ++ +++ L L+ + R ++Y P + GD+ CA F ED
Sbjct: 1311 VSHINDLSDFYVQLIEDEAEISHLSERLNS----VKTRPEYYVGPPLQRGDMICAVFPED 1366
Query: 556 DQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAGVKPS 615
+ WYRA + + + V ++DYGN ++ ++ + LP I C L G +
Sbjct: 1367 NLWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIHCSLQGFEVP 1426
Query: 616 LGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPHVSVSKVLLDAGFAVG 675
+ + + + I + V K ++ V L D+ H ++ ++ + +A+
Sbjct: 1427 DNKNSKKMMHYFSQRTSEAAIRCEFV-KFQDRWEVILADE----HGIIADDMI-SRYALS 1480
Query: 676 EQSMVTDKPSDVKETSVPLGVEGKVNP---LEWTWVELGVDQTVDVVVCVIYSPGEFYCH 732
E+S V +K S + ++ L W E + + VI P F+C
Sbjct: 1481 EKSQVELSTQVIKSASSKSVNKSDIDTSVFLNWYNPE---KKMIRAYATVIDGPEYFWCQ 1537
Query: 733 VLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFFAGDGSWYRALVKEILPNGH 792
+ L+ L ++ E + IG PC + DG +YRAL+ I +
Sbjct: 1538 FADTEKLQCLEVEVQTAGEQVADRRNCIPCPYIGDPCIVRYREDGHYYRALITNICEDYL 1597
Query: 793 VKVHFVDYGNIEE-VTADELRMISSTFLNLPFQGIRCQLADIQSRNKHWSEEAITRFQMC 851
V V VD+GNIE+ V L I S L++P Q C L+ S+E F
Sbjct: 1598 VSVRLVDFGNIEDCVDPKALWAIPSELLSVPMQAFPCCLSGFNISEGLCSQEGNDYFYEI 1657
Query: 852 VAGIKLQARVVEVTEN--GIGVELTDLSTCYPRIISDVLIDEHLVLKSASPHKDLPND 907
+ L+ ++E+ + I + + DL + I + +KSA P++++ ++
Sbjct: 1658 ITEDVLEITILEIRRDVCDIPLAIVDLKSKGKSINEKMEKYSKTGIKSALPYENIDSE 1715
Score = 85.9 bits (211), Expect = 2e-16
Identities = 112/421 (26%), Positives = 169/421 (40%), Gaps = 43/421 (10%)
Query: 655 KSETPHVSVSKVLLDAGFAV-GEQSMVTDKPSDVKETSVPLGVEG---KVNPLEWTWVEL 710
K E SVSK L D G +V + VK SV + ++ P + EL
Sbjct: 711 KRENKTTSVSKALSDTTVVTNGSTELVVQEK--VKRASVYFPLMQNCLEIKPGSSSKGEL 768
Query: 711 GVDQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCC 770
V TV+V V + +PG F+C + + ++ L L + +C+ + + C
Sbjct: 769 EVGSTVEVRVSYVENPGYFWCQLTRN--IQGLKTLMSDIQYYCKNTAAPHQRNTLA--CL 824
Query: 771 AFFAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQL 830
A + W RAL+ I HV V FVDYG+ E V+ + IS FL + Q RC L
Sbjct: 825 AKRTVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQAFRCSL 884
Query: 831 AD-IQSRNKH---WSEEAITRFQMCVAGI---KLQARVVEVTENGIGVELTDLSTCYPRI 883
+ IQ ++ W +AI F + L+ + I EL ++
Sbjct: 885 YNLIQPVGQNPFVWDVKAIQAFNEFIDNAWQKNLELKCTIFALASINEELFNI------- 937
Query: 884 ISDVLIDEHLVLKSASPHKDLPNDRLVNKHELQVHVQGLQATSSAEQWKTIELPVDKTIQ 943
+D +SA L RL +LQ ++ S + T ++ +
Sbjct: 938 -----VDLLTPFQSACHF--LVEKRLARPVKLQKPLESSVQLHSYF-YSTHDMKIGSEEL 989
Query: 944 ANVLEIISPNLFYA-LPKGMPENQEKLCMLTAELLEYCNAPKSRPPYRPRIGDACCAKYT 1002
+ I P FY L + ++ C +T N S P P G C AKYT
Sbjct: 990 VYITHIDDPWTFYCQLARNANILEQLSCSITQLSKVLLNLKTS--PLNP--GTLCLAKYT 1045
Query: 1003 SDDFWYRAVVLGTSDTDVEVLYADYGNIETLPLCRVQPITSSH---LALPFQIIRCSLEG 1059
D WYR +V+ +V + D+GNI + + PI S L LP Q +RCSL
Sbjct: 1046 -DGNWYRGIVIEKEPK--KVFFVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQAVRCSLSD 1102
Query: 1060 L 1060
+
Sbjct: 1103 I 1103
Score = 85.5 bits (210), Expect = 3e-16
Identities = 94/364 (25%), Positives = 149/364 (40%), Gaps = 36/364 (9%)
Query: 718 VVVCVIYSPGEFYCHVLKEDALKKLNDLNKSL-AEHCQQKLPNGFKAEIGQPCCAFFAGD 776
V V I +FY +++++A +++ L++ L + + + G + G CA F D
Sbjct: 1309 VYVSHINDLSDFYVQLIEDEA--EISHLSERLNSVKTRPEYYVGPPLQRGDMICAVFPED 1366
Query: 777 GSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQ-- 834
WYRA++KE PN + V F+DYGN+ V +++ + LP I C L +
Sbjct: 1367 NLWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIHCSLQGFEVP 1426
Query: 835 -----SRNKHWSEEAITRFQMCVAGIKLQARVVEVTENGIGVELTDLSTCYPRIISDVLI 889
+ H+ + + + +K Q R + + G+ D+ + Y +
Sbjct: 1427 DNKNSKKMMHYFSQRTSEAAIRCEFVKFQDRWEVILADEHGIIADDMISRYALSEKSQVE 1486
Query: 890 DEHLVLKSASPHKDLPNDRLVNKHELQVHVQGLQATSSAEQWKTIELPVDKTIQANVLEI 949
V+KSAS + VNK ++ TS W P K I+A I
Sbjct: 1487 LSTQVIKSAS-------SKSVNKSDID--------TSVFLNWYN---PEKKMIRAYATVI 1528
Query: 950 ISPNLFYALPKGMPENQEKLCMLTAELLEYCN--APKSRPPYRPRIGDACCAKYTSDDFW 1007
P F+ + EKL L E+ A + P IGD C +Y D +
Sbjct: 1529 DGPEYFWC----QFADTEKLQCLEVEVQTAGEQVADRRNCIPCPYIGDPCIVRYREDGHY 1584
Query: 1008 YRAVVLG-TSDTDVEVLYADYGNIE-TLPLCRVQPITSSHLALPFQIIRCSLEGLMELNG 1065
YRA++ D V V D+GNIE + + I S L++P Q C L G G
Sbjct: 1585 YRALITNICEDYLVSVRLVDFGNIEDCVDPKALWAIPSELLSVPMQAFPCCLSGFNISEG 1644
Query: 1066 SSSQ 1069
SQ
Sbjct: 1645 LCSQ 1648
Score = 82.8 bits (203), Expect = 2e-15
Identities = 93/384 (24%), Positives = 159/384 (41%), Gaps = 36/384 (9%)
Query: 270 VTEFKHPGDFYVQLYSSEVLEYMNQLSASLKETYANVHEKDYIPV-KGEVCIAKYTVDQT 328
V+ DFYVQL E ++ LS L P+ +G++ A + D
Sbjct: 1311 VSHINDLSDFYVQLIEDEA--EISHLSERLNSVKTRPEYYVGPPLQRGDMICAVFPEDNL 1368
Query: 329 WNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCFVANV-IPA 387
W RA+I+ + V +IDYGN ++ N+I L+ + P I C + +P
Sbjct: 1369 WYRAVIKEQQPNDLLS-VQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIHCSLQGFEVPD 1427
Query: 388 EGNWSSDCIKATKPLLMEQYCSIKIVDILEEEVVTFAVEVELPNSGKLLD--HVLIEMGY 445
N S K++ + A+ E K D V++ +
Sbjct: 1428 NKN------------------SKKMMHYFSQRTSEAAIRCEFV---KFQDRWEVILADEH 1466
Query: 446 GLKPSGQDSKKENADQSDPE-DVGKMTTENNIVVDKSDLIPKVLTLNVGDEFCGVVAH-- 502
G+ S+ +++S E + + ++ V+KSD+ V E + A+
Sbjct: 1467 GIIADDMISRYALSEKSQVELSTQVIKSASSKSVNKSDIDTSVFLNWYNPEKKMIRAYAT 1526
Query: 503 -IQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDFYPA--IGDICCAQFSEDDQWY 559
I PE F+C Q KL L+ + +Q+ R + P IGD C ++ ED +Y
Sbjct: 1527 VIDGPEYFWC-QFADTEKLQCLEVEVQTAGEQVADRRNCIPCPYIGDPCIVRYREDGHYY 1585
Query: 560 RASVLAYASEESVLVGYVDYGNFE-ILSLMRLCPIIPKLLELPMQAIKCVLAGVKPSLGI 618
RA + + V V VD+GN E + L I +LL +PMQA C L+G S G+
Sbjct: 1586 RALITNICEDYLVSVRLVDFGNIEDCVDPKALWAIPSELLSVPMQAFPCCLSGFNISEGL 1645
Query: 619 WTPEAICLMKKLVQNKIITVKVVD 642
+ E +++ ++ + +++
Sbjct: 1646 CSQEGNDYFYEIITEDVLEITILE 1669
Score = 41.2 bits (95), Expect = 0.006
Identities = 49/221 (22%), Positives = 90/221 (40%), Gaps = 7/221 (3%)
Query: 266 IKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASLKETYANVHEKDYIPVKGEVCIAKYTV 325
I+ T P F+ Q +E L+ + + E A+ P G+ CI +Y
Sbjct: 1521 IRAYATVIDGPEYFWCQFADTEKLQCLEVEVQTAGEQVADRRNCIPCPYIGDPCIVRYRE 1580
Query: 326 DQTWNRAIIQNVDVQQKKAHVLYIDYGN-EEIIPLNRIYHLNRNIDLFPPCAIKCFVANV 384
D + RA+I N+ + V +D+GN E+ + ++ + + P A C ++
Sbjct: 1581 DGHYYRALITNI-CEDYLVSVRLVDFGNIEDCVDPKALWAIPSELLSVPMQAFPCCLSGF 1639
Query: 385 IPAEGNWSSDCIKATKPLLMEQYCSIKIVDILEEEVVTFAVEVELPNSGKLLDHVLIEMG 444
+EG S + ++ E I I++I + V+L + GK ++ + +
Sbjct: 1640 NISEGLCSQEGNDYFYEIITEDVLEITILEIRRDVCDIPLAIVDLKSKGKSINEKMEKYS 1699
Query: 445 -YGLKPS----GQDSKKENADQSDPEDVGKMTTENNIVVDK 480
G+K + DS+ + S DVG N V +K
Sbjct: 1700 KTGIKSALPYENIDSEIKQTLGSYNLDVGLKKLSNKAVQNK 1740
>gi|94421471 ring finger protein 17 [Homo sapiens]
Length = 1623
Score = 119 bits (299), Expect = 1e-26
Identities = 173/782 (22%), Positives = 306/782 (39%), Gaps = 83/782 (10%)
Query: 374 PCAIKCFVANVIPAEGN--WSSDCIKATKPLLMEQYCSIKIVDILEEEVVTFAVEVELPN 431
P A C + +++P N W + ++ + S+K+ EE V+++ P
Sbjct: 571 PLAQPCSLKDIVPQNSNEGWEEEAKVEFLKMVNNKAVSMKV---FREEDGVLIVDLQKPP 627
Query: 432 SGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPEDVGKMTTENNIVVDKSDLIPKVLTLN 491
K+ + + + L K + +S E +N + ++PK +T
Sbjct: 628 PNKISSDMPVSLRDALVFMELAKFKSQSLRSHFE-------KNTTLHYHPPILPKEMT-- 678
Query: 492 VGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDFYPAIGDICCAQ 551
+ V HI +P DF+ Q ++ L L+ Y + + + D C
Sbjct: 679 ---DVSVTVCHINSPGDFYLQLIEGLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVA 735
Query: 552 FSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAG 611
ED WYRA V+ + V V YVD+GN +++ + I + L P +AIKC LA
Sbjct: 736 KFEDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKLAY 795
Query: 612 VKPSLGI--WTPEAICLMKKLVQNKIITVKVVDKLE-NSSLVELIDKSETPHV---SVSK 665
++P W+ EA ++ Q+K +T V+ LE N LVEL D P + S++
Sbjct: 796 IEPYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDSLGAPEMTTTSIND 855
Query: 666 VLLDAGFAVGEQSMV----TDKPSDVKETSVPLGVEGKV---NPLEWTWV-----ELGVD 713
L+ G A E + + K +V + S + +V NP+ + + +
Sbjct: 856 QLVKEGLASYEIGYILKDNSQKHIEVWDPSPEEIISNEVHNLNPVSAKSLPNENFQSLYN 915
Query: 714 QTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFF 773
+ + V +C + SP + Y L + L LN L + + + K E C
Sbjct: 916 KELPVHICNVISPEKIYVQWLLTENL--LNSLEEKMIAAYENSKWEPVKWENDMHCAVKI 973
Query: 774 AGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADI 833
W R + ++ + V+V D G V D LR + + + C L DI
Sbjct: 974 QDKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLKTMGRLSLECSLVDI 1033
Query: 834 Q--SRNKHWSEEAITRFQM----CVAGIKLQARVVEVTENGIGVELTDLSTCYPRIISDV 887
+ + W+ A + VA I LQ V+ EN L C V
Sbjct: 1034 RPAGGSDKWTATACDCLSLYLTGAVATIILQ---VDSEENNTTWPLPVKIFCRDEKGERV 1090
Query: 888 LIDEHLVLKSASPHK----DLPNDRLVNKHELQVHVQGLQA-------TSSAEQWKTIEL 936
+ ++L+ K + + +L N +++ L+V ++ + T+ KT ++
Sbjct: 1091 DVSKYLIKKGLALRERRINNLDNSHSLSEKSLEVPLEQEDSVVTNCIKTNFDPDKKTADI 1150
Query: 937 PVDKTI---QANVLE-----------IISPNLFYALPKGMPE----------NQEKLCML 972
++ + Q +LE I + N+F A + + ++ +L +
Sbjct: 1151 ISEQKVSEFQEKILEPRTTRGYKPPAIPNMNVFEATVSCVGDDGTIFVVPKLSEFELIKM 1210
Query: 973 TAELLEYCNAPKSRPPYRPRIGDACCAKYTSDDFWYRAVVLGTSDTDVEVLYADYGNIET 1032
T E+ PY + G+AC + SD WYR V+ V V Y D+G E
Sbjct: 1211 TNEIQSNLKCLGLLEPYFWKKGEACAVR-GSDTLWYRGKVMEVVGGAVRVQYLDHGFTEK 1269
Query: 1033 LPLCRVQPITSSHLALPFQIIRCSLEGLMELNGSSSQLIIMLLKNFMLNQNVMLSVKGIT 1092
+P C + PI + +P I C L + I +L+ + + V + + +
Sbjct: 1270 IPQCHLYPIL-LYPDIPQFCIPCQLHNTTPVGNVWQPDAIEVLQQLLSKRQVDIHIMELP 1328
Query: 1093 KN 1094
KN
Sbjct: 1329 KN 1330
Score = 116 bits (290), Expect = 1e-25
Identities = 191/899 (21%), Positives = 354/899 (39%), Gaps = 123/899 (13%)
Query: 261 KKTMEIKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASLKETYANVHEKDYIPVKGEVCI 320
K+ ++ TV PGDFY+QL + ++ + ++ + + PV+ + C+
Sbjct: 675 KEMTDVSVTVCHINSPGDFYLQLIEGLDILFLLKTIEEFYKSEDGENLEILCPVQDQACV 734
Query: 321 AKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCF 380
AK+ D W RA + + Q+ V Y+D+GN I + + + P AIKC
Sbjct: 735 AKFE-DGIWYRAKVIGLPGHQE-VEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCK 792
Query: 381 VANVIPAEG--NWSSDCIKATKPLLMEQYCSIKIVDILEE--------------EVVTFA 424
+A + P + WS + + + +++ + ++ ILE+ E+ T +
Sbjct: 793 LAYIEPYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDSLGAPEMTTTS 852
Query: 425 VEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPEDVGKMTTENNIVVDKSDLI 484
+ +L G E+GY LK + Q K PE++ N V L
Sbjct: 853 INDQLVKEGL----ASYEIGYILKDNSQ--KHIEVWDPSPEEIISNEVHNLNPVSAKSLP 906
Query: 485 PKVLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASL------SKYCDQLPPRS 538
+ E + ++ +PE + Q L + L L+ + SK+ + + +
Sbjct: 907 NENFQSLYNKELPVHICNVISPEKIYVQWLLTENLLNSLEEKMIAAYENSKW-EPVKWEN 965
Query: 539 DFYPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLL 598
D + C + + +QW R ++ ++ V V D G ++++ L + L
Sbjct: 966 DMH------CAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLK 1019
Query: 599 ELPMQAIKCVLAGVKPSLGI--WTPEAI-CLMKKLVQNKIITVKVVDKLENSSL----VE 651
+ +++C L ++P+ G WT A CL L + VD EN++ V+
Sbjct: 1020 TMGRLSLECSLVDIRPAGGSDKWTATACDCLSLYLTGAVATIILQVDSEENNTTWPLPVK 1079
Query: 652 LIDKSET-PHVSVSKVLLDAGFAVGEQSMVT-DKPSDVKETSVPLGVEGKVNPLEWTWVE 709
+ + E V VSK L+ G A+ E+ + D + E S+ + +E + + + ++
Sbjct: 1080 IFCRDEKGERVDVSKYLIKKGLALRERRINNLDNSHSLSEKSLEVPLE-QEDSVVTNCIK 1138
Query: 710 LGVD---QTVDVVVCVIYSPGEFYCHVL--------KEDALKKLNDLNKS---------- 748
D +T D++ EF +L K A+ +N +
Sbjct: 1139 TNFDPDKKTADII--SEQKVSEFQEKILEPRTTRGYKPPAIPNMNVFEATVSCVGDDGTI 1196
Query: 749 -----LAEHCQQKLPNGFKAEIG-----QP-------CCAFFAGDGSWYRALVKEILPNG 791
L+E K+ N ++ + +P CA D WYR V E++ G
Sbjct: 1197 FVVPKLSEFELIKMTNEIQSNLKCLGLLEPYFWKKGEACAVRGSDTLWYRGKVMEVV-GG 1255
Query: 792 HVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQSRNKHWSEEAITRFQMC 851
V+V ++D+G E++ L I + ++P I CQL + W +AI Q
Sbjct: 1256 AVRVQYLDHGFTEKIPQCHLYPI-LLYPDIPQFCIPCQLHNTTPVGNVWQPDAIEVLQQL 1314
Query: 852 VAGIKLQARVVEVTEN-----GIGVELTDLSTCYPRIISDVLIDEHL-VLKSASPHKDLP 905
++ ++ ++E+ +N I + +S Y EH + P D
Sbjct: 1315 LSKRQVDIHIMELPKNPWEKLSIHLYFDGMSLSYFMAYYKYCTSEHTEEMLKEKPRSD-- 1372
Query: 906 NDRLVNKHELQVHVQGLQA----TSSAEQWKTIELPVDKTIQA-NVLEIISPNLFY---- 956
+D+ + + ++ + L + T + + LP + A V ++SPN Y
Sbjct: 1373 HDKKYEEEQWEIRFEELLSAETDTPLLPPYLSSSLPSPGELYAVQVKHVVSPNEVYICLD 1432
Query: 957 ALPKGMPENQ-----------EKLCMLTAELLEYCNAP-KSRPPYRP-RIGDACCAKYTS 1003
++ NQ E E L+ N ++ PP R C A+Y
Sbjct: 1433 SIETSNQSNQHSDTDDSGVSGESESESLDEALQRVNKKVEALPPLTDFRTEMPCLAEY-D 1491
Query: 1004 DDFWYRAVVLGTSD---TDVEVLYADYGNIETLPLCRVQPITSSHLALPFQIIRCSLEG 1059
D WYRA ++ + + V + DYG+ L L R+ I S + P + I+ L G
Sbjct: 1492 DGLWYRAKIVAIKEFNPLSILVQFVDYGSTAKLTLNRLCQIPSHLMRYPARAIKVLLAG 1550
Score = 94.7 bits (234), Expect = 5e-19
Identities = 139/550 (25%), Positives = 234/550 (42%), Gaps = 84/550 (15%)
Query: 568 SEESVLVGYVD------YGNFEILSLMRLCPIIPK--------LLELPMQAIKCVLAGVK 613
SE ++ G VD + + ++L LC ++ K L ++ A C L +
Sbjct: 523 SEVLIVTGVVDTHVRPEHSAKQHIALNDLCLVLRKSEPYTEGLLKDIQPLAQPCSLKDIV 582
Query: 614 P--SLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPHVSVSKVLLDAG 671
P S W EA K+V NK +++KV + + +V+L + P+ S + +
Sbjct: 583 PQNSNEGWEEEAKVEFLKMVNNKAVSMKVFREEDGVLIVDL--QKPPPNKISSDMPVSLR 640
Query: 672 FAVGEQSMVTDKPSDVK---ETSVPLGVEGKVNPLEWTWVELGVDQTVDVVVCVIYSPGE 728
A+ + K ++ E + L + P E T V V VC I SPG+
Sbjct: 641 DALVFMELAKFKSQSLRSHFEKNTTLHYHPPILPKEMT--------DVSVTVCHINSPGD 692
Query: 729 FYCHVLKE-DALKKLNDLNKSLAEHCQQKLPNGFKAEI-----GQPCCAFFAGDGSWYRA 782
FY +++ D L L + + K +G EI Q C A F DG WYRA
Sbjct: 693 FYLQLIEGLDILFLLKTIEEFY------KSEDGENLEILCPVQDQACVAKFE-DGIWYRA 745
Query: 783 LVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQ--SRNKHW 840
V + + V+V +VD+GN ++T ++R I FLN P + I+C+LA I+ R W
Sbjct: 746 KVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKLAYIEPYKRTMQW 805
Query: 841 SEEAITRFQMCVAGIKLQARVVEVTE-NGIGVELTDLSTCYPRI----ISDVLIDEHL-- 893
S+EA +F+ + V+++ E N + VEL D S P + I+D L+ E L
Sbjct: 806 SKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFD-SLGAPEMTTTSINDQLVKEGLAS 864
Query: 894 -----VLK-SASPHKDL--PNDRLVNKHELQVHVQGLQATSSAEQWKTIELPVDKTIQAN 945
+LK ++ H ++ P+ + +E+ ++ + A S + + +K + +
Sbjct: 865 YEIGYILKDNSQKHIEVWDPSPEEIISNEVH-NLNPVSAKSLPNE--NFQSLYNKELPVH 921
Query: 946 VLEIISPNLFYA---LPKGMPENQEKLCMLTAELLEYCNAPKSRPPYRPRIGDACCAKYT 1002
+ +ISP Y L + + + E+ + E ++ P + C K
Sbjct: 922 ICNVISPEKIYVQWLLTENLLNSLEEKMIAAYENSKW-------EPVKWENDMHCAVKIQ 974
Query: 1003 SDDFWYRA-VVLGTSDTDVEVLYADYG-----NIETLPLCRVQPITSSHLALPFQIIRCS 1056
+ W R ++ +DT VEVL D G N++ L T L+L CS
Sbjct: 975 DKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLKTMGRLSL-----ECS 1029
Query: 1057 LEGLMELNGS 1066
L + GS
Sbjct: 1030 LVDIRPAGGS 1039
Score = 94.0 bits (232), Expect = 8e-19
Identities = 123/513 (23%), Positives = 220/513 (42%), Gaps = 74/513 (14%)
Query: 216 LENKSSIETKDVEVN---NKSDCPLGVTKEIAIWAERIMFSDLRSLQLKKTMEI------ 266
LE + S+ T ++ N +K + ++++ + E+I+ + R+ + K I
Sbjct: 1126 LEQEDSVVTNCIKTNFDPDKKTADIISEQKVSEFQEKIL--EPRTTRGYKPPAIPNMNVF 1183
Query: 267 KGTVTEFKHPGDFYV--QLYSSEVLEYMNQLSASLKETYANVHEKDYIPVKGEVCIAKYT 324
+ TV+ G +V +L E+++ N++ ++LK + Y KGE C + +
Sbjct: 1184 EATVSCVGDDGTIFVVPKLSEFELIKMTNEIQSNLKCLGLL---EPYFWKKGEACAVRGS 1240
Query: 325 VDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCFVANV 384
D W R + ++V V Y+D+G E IP +Y + D+ P I C + N
Sbjct: 1241 -DTLWYRGKV--MEVVGGAVRVQYLDHGFTEKIPQCHLYPILLYPDI-PQFCIPCQLHNT 1296
Query: 385 IPAEGNWSSDCIKATKPLLMEQYCSIKIVDILEEEVVTFAVEVELPNSGKLLDHVLIEMG 444
P W D I+ + LL ++ I I+++ + ++ + G L + +
Sbjct: 1297 TPVGNVWQPDAIEVLQQLLSKRQVDIHIMELPKNPWEKLSIHLYF--DGMSLSYFMAYYK 1354
Query: 445 YGLKPSGQDSKKENA----DQSDPEDVGKMTTENNIVVDK-SDLIPKVLTLNV---GDEF 496
Y ++ KE D+ E+ ++ E + + + L+P L+ ++ G+ +
Sbjct: 1355 YCTSEHTEEMLKEKPRSDHDKKYEEEQWEIRFEELLSAETDTPLLPPYLSSSLPSPGELY 1414
Query: 497 CGVVAHIQTPEDFFC---------QQLQ-------------SGRKLAELQASLSKYCDQL 534
V H+ +P + + Q Q L E ++K + L
Sbjct: 1415 AVQVKHVVSPNEVYICLDSIETSNQSNQHSDTDDSGVSGESESESLDEALQRVNKKVEAL 1474
Query: 535 PPRSDFYPAIGDICCAQFSEDDQWYRASVLAYASEE--SVLVGYVDYGNFEILSLMRLCP 592
PP +DF + C A++ +D WYRA ++A S+LV +VDYG+ L+L RLC
Sbjct: 1475 PPLTDFRTEMP--CLAEY-DDGLWYRAKIVAIKEFNPLSILVQFVDYGSTAKLTLNRLCQ 1531
Query: 593 IIPKLLELPMQAIKCVLAGVKPSL-----------GIWTPEAICLMKKLVQNK-IITVKV 640
I L+ P +AIK +LAG KP L W+ EA+ M +Q K + V +
Sbjct: 1532 IPSHLMRYPARAIKVLLAGFKPPLRDLGETRIPYCPKWSMEALWAMIDCLQGKQLYAVSM 1591
Query: 641 VDKLENSSLVELIDKSETPHVSVSKVLLDAGFA 673
E +V L D + P V L++ G A
Sbjct: 1592 APAPE--QIVTLYDDEQHP---VHMPLVEMGLA 1619
Score = 79.0 bits (193), Expect = 3e-14
Identities = 145/676 (21%), Positives = 257/676 (38%), Gaps = 107/676 (15%)
Query: 276 PGDFYVQLYSSEVLEYMNQLSASLKETYANVHEKDYIPVKGEV---CIAKYTVDQTWNRA 332
P YVQ +E L +N L + Y N + PVK E C K W R
Sbjct: 928 PEKIYVQWLLTENL--LNSLEEKMIAAYEN---SKWEPVKWENDMHCAVKIQDKNQWRRG 982
Query: 333 IIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCFVANVIPAEGN-- 390
I + V VL D G E ++ ++ + L N+ +++C + ++ PA G+
Sbjct: 983 QIIRM-VTDTLVEVLLYDVGVELVVNVDCLRKLEENLKTMGRLSLECSLVDIRPAGGSDK 1041
Query: 391 WSSDCIKATKPLLMEQYCSIKIVDILEEEVVTFAVEVEL---PNSGKLLD--HVLIEMGY 445
W++ L +I + EE T+ + V++ G+ +D LI+ G
Sbjct: 1042 WTATACDCLSLYLTGAVATIILQVDSEENNTTWPLPVKIFCRDEKGERVDVSKYLIKKGL 1101
Query: 446 GLKPSGQDSKKENADQSDPEDVGKMTTENNIVVD--KSDLIPKVLTLNVGDE-------- 495
L+ ++ + S+ + E+++V + K++ P T ++ E
Sbjct: 1102 ALRERRINNLDNSHSLSEKSLEVPLEQEDSVVTNCIKTNFDPDKKTADIISEQKVSEFQE 1161
Query: 496 ---------------------FCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQL 534
F V+ + F S +L ++ + L
Sbjct: 1162 KILEPRTTRGYKPPAIPNMNVFEATVSCVGDDGTIFVVPKLSEFELIKMTNEIQSNLKCL 1221
Query: 535 PPRSDFYPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPII 594
++ G+ C + S D WYR V+ +V V Y+D+G E + L PI+
Sbjct: 1222 GLLEPYFWKKGEACAVRGS-DTLWYRGKVMEVVGG-AVRVQYLDHGFTEKIPQCHLYPIL 1279
Query: 595 PKLLELPMQAIKCVLAGVKPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELID 654
++P I C L P +W P+AI ++++L+ + + + +++ L + +L
Sbjct: 1280 -LYPDIPQFCIPCQLHNTTPVGNVWQPDAIEVLQQLLSKRQVDIHIME-LPKNPWEKLSI 1337
Query: 655 KSETPHVSVSKVLLDAGFAVGE--QSMVTDKPSDVKETSVPLGVEGKVNPLEWTWVELGV 712
+S+S + + E + M+ +KP + + ++ E E
Sbjct: 1338 HLYFDGMSLSYFMAYYKYCTSEHTEEMLKEKPRSDHDKKYE-EEQWEIRFEELLSAETDT 1396
Query: 713 DQTVDVVVCVIYSPGEFYCHVLKE-----------DALKKLNDLNK-------------- 747
+ + SPGE Y +K D+++ N N+
Sbjct: 1397 PLLPPYLSSSLPSPGELYAVQVKHVVSPNEVYICLDSIETSNQSNQHSDTDDSGVSGESE 1456
Query: 748 --SLAEHCQ------QKLP--NGFKAEIGQPCCAFFAGDGSWYRA---LVKEILPNGHVK 794
SL E Q + LP F+ E+ PC A + DG WYRA +KE P +
Sbjct: 1457 SESLDEALQRVNKKVEALPPLTDFRTEM--PCLAEY-DDGLWYRAKIVAIKEFNPLS-IL 1512
Query: 795 VHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQSRNK-----------HWSEE 843
V FVDYG+ ++T + L I S + P + I+ LA + + WS E
Sbjct: 1513 VQFVDYGSTAKLTLNRLCQIPSHLMRYPARAIKVLLAGFKPPLRDLGETRIPYCPKWSME 1572
Query: 844 AITRFQMCVAGIKLQA 859
A+ C+ G +L A
Sbjct: 1573 ALWAMIDCLQGKQLYA 1588
>gi|112293287 tudor domain containing 7 [Homo sapiens]
Length = 1098
Score = 109 bits (272), Expect = 2e-23
Identities = 159/620 (25%), Positives = 246/620 (39%), Gaps = 107/620 (17%)
Query: 326 DQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCFVANVI 385
+ W RA Q + ++ K V Y+DYG E + ++ Y LN A KC +A +
Sbjct: 526 EDAWLRA--QVISTEENKIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCKLAGL- 582
Query: 386 PAEGNWSSDCIKATKPLLMEQYCSIKIVDILEEEVVTFAVEVELPNSGKLLDHVLIEMGY 445
+L + +K+V+ L + FAVE+ LD I +
Sbjct: 583 ---------------EVLSDDPDLVKVVESLTCGKI-FAVEI--------LDKADIPLVV 618
Query: 446 GLKPSGQDSKKENADQSDPEDVGKMTTENNIVVDKSDLIPKVLTLNVGDEFCGV-VAHIQ 504
SG+D NA T + DKS + L V + V V +I
Sbjct: 619 LYDTSGEDDININA------------TCLKAICDKS----LEVHLQVDAMYTNVKVTNIC 662
Query: 505 TPEDFFCQQLQSG-RKLAELQASLSKYCDQLPPRSDFY---PAIGDICCAQFSEDDQWYR 560
+ +CQ G KL++L + Y S+ + P G IC F +W R
Sbjct: 663 SDGTLYCQVPCKGLNKLSDLLRKIEDYFHCKHMTSECFVSLPFCGKICL--FHCKGKWLR 720
Query: 561 ASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLE----LPMQAIKCVLAGVKPSL 616
+ S ++ V ++D G + + L I P+ L+ +P QAIKC LA + S+
Sbjct: 721 VEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCLADLPQSI 780
Query: 617 GIWTPEAICLMKKLVQNKI---ITVKVVDKLENSSLVELIDKSE--TPHVSVSKVLLDAG 671
G+WTP+A+ ++ V N I V VD+ + V L PH S+++ + +A
Sbjct: 781 GMWTPDAVLWLRDSVLNCSDCSIKVTKVDETRGIAHVYLFTPKNFPDPHRSINRQITNAD 840
Query: 672 FAVGEQSMV-------TDKPSDVKETSVPL-GVEGKVNPLEWTWV--ELGVDQT------ 715
++ + D P+ K ++P+ G G+ T V + VD T
Sbjct: 841 LWKHQKDVFLSAISSGADSPNS-KNGNMPMSGNTGENFRKNLTDVIKKSMVDHTSAFSTE 899
Query: 716 --------------VDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGF 761
+DV V V PG F +E + KL L + + +
Sbjct: 900 ELPPPVHLSKPGEHMDVYVPVACHPGYFVIQPWQE--IHKLEVLMEEMILYYSVSEERHI 957
Query: 762 KAEIGQPCCAFFAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNL 821
E Q A + W+R L+K IL NG V V+ +DYG E V +++ + F L
Sbjct: 958 AVEKDQVYAAKV--ENKWHRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKL 1015
Query: 822 PFQGIRCQLADIQSRNKHWSEEAITRFQMCVAGIKLQARVVEVTENG-----------IG 870
PFQ + QLA ++ WSEEA F+ V L A V V EN +
Sbjct: 1016 PFQAVTAQLAGVKC--NQWSEEASMVFRNHVEKKPLVALVQTVIENANPWDRKVVVYLVD 1073
Query: 871 VELTDLSTCYPRIISDVLID 890
L D T +S+ LI+
Sbjct: 1074 TSLPDTDTWIHDFMSEYLIE 1093
Score = 105 bits (263), Expect = 2e-22
Identities = 142/584 (24%), Positives = 237/584 (40%), Gaps = 86/584 (14%)
Query: 553 SEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAGV 612
+E+D W RA V++ E + V YVDYG E + + + PK L QA KC LAG+
Sbjct: 524 AEEDAWLRAQVIS-TEENKIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCKLAGL 582
Query: 613 KPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPHVSVSKVLLDAGF 672
+ P+ + +++ L KI V+++DK + LV L D S ++++ L A
Sbjct: 583 EVLSD--DPDLVKVVESLTCGKIFAVEILDKAD-IPLVVLYDTSGEDDININATCLKA-- 637
Query: 673 AVGEQSMVTDKPSDVKETSVPLGVEGKVNPLEWTWVELGVD-QTVDVVVCVIYSPGEFYC 731
+ DK + V L VD +V V I S G YC
Sbjct: 638 -------ICDKSLE---------------------VHLQVDAMYTNVKVTNICSDGTLYC 669
Query: 732 HVLKEDALKKLNDLNKSLAE--HCQQKLPNGFKAEIGQPCC---AFFAGDGSWYRALVKE 786
V + L KL+DL + + + HC+ F + P C F G W R +
Sbjct: 670 QVPCK-GLNKLSDLLRKIEDYFHCKHMTSECF---VSLPFCGKICLFHCKGKWLRVEITN 725
Query: 787 ILPNGHVKVHFVDYGNIEEVTADELRMISSTFLN----LPFQGIRCQLADIQSRNKHWSE 842
+ + + V F+D G + V ELR I FL +P Q I+C LAD+ W+
Sbjct: 726 VHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCLADLPQSIGMWTP 785
Query: 843 EAITRFQMCVAGIK-LQARVVEVTE-NGIG-------VELTDLSTCYPRIISDVLIDEH- 892
+A+ + V +V +V E GI D R I++ + +H
Sbjct: 786 DAVLWLRDSVLNCSDCSIKVTKVDETRGIAHVYLFTPKNFPDPHRSINRQITNADLWKHQ 845
Query: 893 --LVLKSASPHKDLPNDRLVN------------KHELQVHVQGLQATSSAEQWKTIELPV 938
+ L + S D PN + N K+ V + + +SA + + PV
Sbjct: 846 KDVFLSAISSGADSPNSKNGNMPMSGNTGENFRKNLTDVIKKSMVDHTSAFSTEELPPPV 905
Query: 939 DKTIQANVLEI-----ISPNLFYALPKGMPENQEKLCMLTAELLEYCNAPKSRPPYRPRI 993
+ +++ P F P + KL +L E++ Y + + R
Sbjct: 906 HLSKPGEHMDVYVPVACHPGYFVIQPW---QEIHKLEVLMEEMILYYSVSEER-HIAVEK 961
Query: 994 GDACCAKYTSDDFWYRAVVLG-TSDTDVEVLYADYGNIETLPLCRVQPITSSHLALPFQI 1052
AK ++ W+R ++ G ++ V V DYG E + + +VQP+ LPFQ
Sbjct: 962 DQVYAAKV--ENKWHRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQA 1019
Query: 1053 IRCSLEGLMELNGSSSQLIIMLLKNFMLNQNVMLSVKGITKNVH 1096
+ L G+ S+ M+ +N + + ++ V+ + +N +
Sbjct: 1020 VTAQLAGVK--CNQWSEEASMVFRNHVEKKPLVALVQTVIENAN 1061
Score = 68.9 bits (167), Expect = 3e-11
Identities = 103/482 (21%), Positives = 191/482 (39%), Gaps = 64/482 (13%)
Query: 227 VEVNNKSDCPLGVT------KEIAIWAERIMFSDLRSLQLKKTMEIKGT---VTEFKHPG 277
VE+ +K+D PL V +I I A + +SL++ ++ T VT G
Sbjct: 606 VEILDKADIPLVVLYDTSGEDDININATCLKAICDKSLEVHLQVDAMYTNVKVTNICSDG 665
Query: 278 DFYVQLYSSEVLEYMNQLSASLKETYANVHEKDY-------IPVKGEVCIAKYTVDQTWN 330
Y Q+ + +N+LS L++ H K +P G++C+ + W
Sbjct: 666 TLYCQV----PCKGLNKLSDLLRKIEDYFHCKHMTSECFVSLPFCGKICL--FHCKGKWL 719
Query: 331 RAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLN----RNIDLFPPCAIKCFVANVIP 386
R I NV + V ++D G + ++ + + + + PP AIKC +A++
Sbjct: 720 RVEITNVH-SSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCLADLPQ 778
Query: 387 AEGNWSSDCIKATKPLLME-QYCSIKIVDILEEEVVTFA---VEVELPNSGKLLDHVLI- 441
+ G W+ D + + ++ CSIK+ + E + P+ + ++ +
Sbjct: 779 SIGMWTPDAVLWLRDSVLNCSDCSIKVTKVDETRGIAHVYLFTPKNFPDPHRSINRQITN 838
Query: 442 --------EMGYGLKPSGQDSKK-------------ENADQSDPEDVGKMTTENNIVVDK 480
++ SG DS EN ++ + + K ++
Sbjct: 839 ADLWKHQKDVFLSAISSGADSPNSKNGNMPMSGNTGENFRKNLTDVIKKSMVDHTSAFST 898
Query: 481 SDLIPKVLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDF 540
+L P V G+ V P F Q Q KL L + Y R
Sbjct: 899 EELPPPVHLSKPGEHMDVYVPVACHPGYFVIQPWQEIHKLEVLMEEMILYYSVSEER--- 955
Query: 541 YPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLEL 600
+ A+ +++W+R + + V V +DYG E++++ ++ P++ +L
Sbjct: 956 HIAVEKDQVYAAKVENKWHRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKL 1015
Query: 601 PMQAIKCVLAGVKPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSS------LVELID 654
P QA+ LAGVK W+ EA + + V+ K + V +EN++ +V L+D
Sbjct: 1016 PFQAVTAQLAGVK--CNQWSEEASMVFRNHVEKKPLVALVQTVIENANPWDRKVVVYLVD 1073
Query: 655 KS 656
S
Sbjct: 1074 TS 1075
Score = 48.1 bits (113), Expect = 5e-05
Identities = 41/170 (24%), Positives = 73/170 (42%), Gaps = 10/170 (5%)
Query: 901 HKDLPNDRLVNKHELQVHVQGLQATSSAEQWKTIE---LPVDKTIQANVLEIISPN--LF 955
H D +V + LQV ++ ++ + T+ +P + + V+E+ + N +
Sbjct: 421 HGDNDIKAMVEQEYLQVEESIAESANTFMEDITVPPLMIPTEASPSVLVVELSNTNEVVI 480
Query: 956 YALPKGMPENQEKLCMLTAELLEYCNA-PKSRPPYRPRIGDACCAKYTSDDFWYRAVVLG 1014
+ K QE ++ E+ EY + PK P +G +D W RA V+
Sbjct: 481 RYVGKDYSAAQE---LMEDEMKEYYSKNPKITPVQAVNVGQLLAVN-AEEDAWLRAQVIS 536
Query: 1015 TSDTDVEVLYADYGNIETLPLCRVQPITSSHLALPFQIIRCSLEGLMELN 1064
T + ++V Y DYG E + + + +L FQ +C L GL L+
Sbjct: 537 TEENKIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCKLAGLEVLS 586
>gi|145312259 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 89.4 bits (220), Expect = 2e-17
Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 4/160 (2%)
Query: 713 DQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAF 772
D+ ++V V P F+ ++ +L+ L+ L + +H + +P +G A
Sbjct: 305 DEYLEVYVSASEHPNHFWIQIVGSRSLQ-LDKLVNEMTQHYENSVPEDLTVHVGDIVAAP 363
Query: 773 FAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLAD 832
+GSWYRA V L NG++ ++FVD+G+ + +LR + S FL+LPFQ I C LA
Sbjct: 364 LPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLAR 423
Query: 833 IQSRNKHWSEEAITRFQM---CVAGIKLQARVVEVTENGI 869
I W EEA+ F C L A++ + GI
Sbjct: 424 IAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGI 463
Score = 57.4 bits (137), Expect = 8e-08
Identities = 53/205 (25%), Positives = 91/205 (44%), Gaps = 17/205 (8%)
Query: 494 DEFCGV-VAHIQTPEDFFCQQLQS-GRKLAELQASLSKYCDQLPPRSDFYPAIGDICCAQ 551
DE+ V V+ + P F+ Q + S +L +L ++++ + P D +GDI A
Sbjct: 305 DEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPE-DLTVHVGDIVAAP 363
Query: 552 FSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAG 611
+ WYRA VL ++ + +VD+G+ L L + L LP QAI+C LA
Sbjct: 364 LPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLAR 423
Query: 612 VKPSLGIWTPEAICLMKKLVQN---KIITVKVVDKLENS----SLVELIDKSETPHVSVS 664
+ PS W EA+ +L K + K+ ++ + L D S + +
Sbjct: 424 IAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIG 483
Query: 665 KVLLDAGFAVGEQSMVTDKPSDVKE 689
L+ G+A+ + P D++E
Sbjct: 484 LELVHKGYAI-------ELPEDIEE 501
Score = 50.1 bits (118), Expect = 1e-05
Identities = 25/66 (37%), Positives = 40/66 (60%), Gaps = 1/66 (1%)
Query: 993 IGDACCAKYTSDDFWYRAVVLGTSDT-DVEVLYADYGNIETLPLCRVQPITSSHLALPFQ 1051
+GD A ++ WYRA VLGT + ++++ + D+G+ PL ++ + S L+LPFQ
Sbjct: 356 VGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQ 415
Query: 1052 IIRCSL 1057
I CSL
Sbjct: 416 AIECSL 421
Score = 49.3 bits (116), Expect = 2e-05
Identities = 28/127 (22%), Positives = 60/127 (47%), Gaps = 2/127 (1%)
Query: 270 VTEFKHPGDFYVQLYSSEVLEYMNQLSASLKETYANVHEKDYIPVKGEVCIAKYTVDQTW 329
V+ +HP F++Q+ S L+ +++L + + Y N +D G++ A + +W
Sbjct: 312 VSASEHPNHFWIQIVGSRSLQ-LDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSW 370
Query: 330 NRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCFVANVIPAEG 389
RA + ++ + ++D+G+ PL + L + P AI+C +A + P+
Sbjct: 371 YRARVLGT-LENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGD 429
Query: 390 NWSSDCI 396
W + +
Sbjct: 430 QWEEEAL 436
>gi|145312246 tudor and KH domain containing isoform b [Homo
sapiens]
Length = 516
Score = 89.4 bits (220), Expect = 2e-17
Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 4/160 (2%)
Query: 713 DQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAF 772
D+ ++V V P F+ ++ +L+ L+ L + +H + +P +G A
Sbjct: 260 DEYLEVYVSASEHPNHFWIQIVGSRSLQ-LDKLVNEMTQHYENSVPEDLTVHVGDIVAAP 318
Query: 773 FAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLAD 832
+GSWYRA V L NG++ ++FVD+G+ + +LR + S FL+LPFQ I C LA
Sbjct: 319 LPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLAR 378
Query: 833 IQSRNKHWSEEAITRFQM---CVAGIKLQARVVEVTENGI 869
I W EEA+ F C L A++ + GI
Sbjct: 379 IAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGI 418
Score = 57.4 bits (137), Expect = 8e-08
Identities = 53/205 (25%), Positives = 91/205 (44%), Gaps = 17/205 (8%)
Query: 494 DEFCGV-VAHIQTPEDFFCQQLQS-GRKLAELQASLSKYCDQLPPRSDFYPAIGDICCAQ 551
DE+ V V+ + P F+ Q + S +L +L ++++ + P D +GDI A
Sbjct: 260 DEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPE-DLTVHVGDIVAAP 318
Query: 552 FSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAG 611
+ WYRA VL ++ + +VD+G+ L L + L LP QAI+C LA
Sbjct: 319 LPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLAR 378
Query: 612 VKPSLGIWTPEAICLMKKLVQN---KIITVKVVDKLENS----SLVELIDKSETPHVSVS 664
+ PS W EA+ +L K + K+ ++ + L D S + +
Sbjct: 379 IAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIG 438
Query: 665 KVLLDAGFAVGEQSMVTDKPSDVKE 689
L+ G+A+ + P D++E
Sbjct: 439 LELVHKGYAI-------ELPEDIEE 456
Score = 50.1 bits (118), Expect = 1e-05
Identities = 25/66 (37%), Positives = 40/66 (60%), Gaps = 1/66 (1%)
Query: 993 IGDACCAKYTSDDFWYRAVVLGTSDT-DVEVLYADYGNIETLPLCRVQPITSSHLALPFQ 1051
+GD A ++ WYRA VLGT + ++++ + D+G+ PL ++ + S L+LPFQ
Sbjct: 311 VGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQ 370
Query: 1052 IIRCSL 1057
I CSL
Sbjct: 371 AIECSL 376
Score = 49.3 bits (116), Expect = 2e-05
Identities = 28/127 (22%), Positives = 60/127 (47%), Gaps = 2/127 (1%)
Query: 270 VTEFKHPGDFYVQLYSSEVLEYMNQLSASLKETYANVHEKDYIPVKGEVCIAKYTVDQTW 329
V+ +HP F++Q+ S L+ +++L + + Y N +D G++ A + +W
Sbjct: 267 VSASEHPNHFWIQIVGSRSLQ-LDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSW 325
Query: 330 NRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCFVANVIPAEG 389
RA + ++ + ++D+G+ PL + L + P AI+C +A + P+
Sbjct: 326 YRARVLGT-LENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGD 384
Query: 390 NWSSDCI 396
W + +
Sbjct: 385 QWEEEAL 391
>gi|145312270 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 89.4 bits (220), Expect = 2e-17
Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 4/160 (2%)
Query: 713 DQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAF 772
D+ ++V V P F+ ++ +L+ L+ L + +H + +P +G A
Sbjct: 305 DEYLEVYVSASEHPNHFWIQIVGSRSLQ-LDKLVNEMTQHYENSVPEDLTVHVGDIVAAP 363
Query: 773 FAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLAD 832
+GSWYRA V L NG++ ++FVD+G+ + +LR + S FL+LPFQ I C LA
Sbjct: 364 LPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLAR 423
Query: 833 IQSRNKHWSEEAITRFQM---CVAGIKLQARVVEVTENGI 869
I W EEA+ F C L A++ + GI
Sbjct: 424 IAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGI 463
Score = 57.4 bits (137), Expect = 8e-08
Identities = 53/205 (25%), Positives = 91/205 (44%), Gaps = 17/205 (8%)
Query: 494 DEFCGV-VAHIQTPEDFFCQQLQS-GRKLAELQASLSKYCDQLPPRSDFYPAIGDICCAQ 551
DE+ V V+ + P F+ Q + S +L +L ++++ + P D +GDI A
Sbjct: 305 DEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPE-DLTVHVGDIVAAP 363
Query: 552 FSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAG 611
+ WYRA VL ++ + +VD+G+ L L + L LP QAI+C LA
Sbjct: 364 LPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLAR 423
Query: 612 VKPSLGIWTPEAICLMKKLVQN---KIITVKVVDKLENS----SLVELIDKSETPHVSVS 664
+ PS W EA+ +L K + K+ ++ + L D S + +
Sbjct: 424 IAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIG 483
Query: 665 KVLLDAGFAVGEQSMVTDKPSDVKE 689
L+ G+A+ + P D++E
Sbjct: 484 LELVHKGYAI-------ELPEDIEE 501
Score = 50.1 bits (118), Expect = 1e-05
Identities = 25/66 (37%), Positives = 40/66 (60%), Gaps = 1/66 (1%)
Query: 993 IGDACCAKYTSDDFWYRAVVLGTSDT-DVEVLYADYGNIETLPLCRVQPITSSHLALPFQ 1051
+GD A ++ WYRA VLGT + ++++ + D+G+ PL ++ + S L+LPFQ
Sbjct: 356 VGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQ 415
Query: 1052 IIRCSL 1057
I CSL
Sbjct: 416 AIECSL 421
Score = 49.3 bits (116), Expect = 2e-05
Identities = 28/127 (22%), Positives = 60/127 (47%), Gaps = 2/127 (1%)
Query: 270 VTEFKHPGDFYVQLYSSEVLEYMNQLSASLKETYANVHEKDYIPVKGEVCIAKYTVDQTW 329
V+ +HP F++Q+ S L+ +++L + + Y N +D G++ A + +W
Sbjct: 312 VSASEHPNHFWIQIVGSRSLQ-LDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSW 370
Query: 330 NRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCFVANVIPAEG 389
RA + ++ + ++D+G+ PL + L + P AI+C +A + P+
Sbjct: 371 YRARVLGT-LENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGD 429
Query: 390 NWSSDCI 396
W + +
Sbjct: 430 QWEEEAL 436
>gi|145312256 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 89.4 bits (220), Expect = 2e-17
Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 4/160 (2%)
Query: 713 DQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAF 772
D+ ++V V P F+ ++ +L+ L+ L + +H + +P +G A
Sbjct: 305 DEYLEVYVSASEHPNHFWIQIVGSRSLQ-LDKLVNEMTQHYENSVPEDLTVHVGDIVAAP 363
Query: 773 FAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLAD 832
+GSWYRA V L NG++ ++FVD+G+ + +LR + S FL+LPFQ I C LA
Sbjct: 364 LPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLAR 423
Query: 833 IQSRNKHWSEEAITRFQM---CVAGIKLQARVVEVTENGI 869
I W EEA+ F C L A++ + GI
Sbjct: 424 IAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGI 463
Score = 57.4 bits (137), Expect = 8e-08
Identities = 53/205 (25%), Positives = 91/205 (44%), Gaps = 17/205 (8%)
Query: 494 DEFCGV-VAHIQTPEDFFCQQLQS-GRKLAELQASLSKYCDQLPPRSDFYPAIGDICCAQ 551
DE+ V V+ + P F+ Q + S +L +L ++++ + P D +GDI A
Sbjct: 305 DEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPE-DLTVHVGDIVAAP 363
Query: 552 FSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAG 611
+ WYRA VL ++ + +VD+G+ L L + L LP QAI+C LA
Sbjct: 364 LPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLAR 423
Query: 612 VKPSLGIWTPEAICLMKKLVQN---KIITVKVVDKLENS----SLVELIDKSETPHVSVS 664
+ PS W EA+ +L K + K+ ++ + L D S + +
Sbjct: 424 IAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIG 483
Query: 665 KVLLDAGFAVGEQSMVTDKPSDVKE 689
L+ G+A+ + P D++E
Sbjct: 484 LELVHKGYAI-------ELPEDIEE 501
Score = 50.1 bits (118), Expect = 1e-05
Identities = 25/66 (37%), Positives = 40/66 (60%), Gaps = 1/66 (1%)
Query: 993 IGDACCAKYTSDDFWYRAVVLGTSDT-DVEVLYADYGNIETLPLCRVQPITSSHLALPFQ 1051
+GD A ++ WYRA VLGT + ++++ + D+G+ PL ++ + S L+LPFQ
Sbjct: 356 VGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQ 415
Query: 1052 IIRCSL 1057
I CSL
Sbjct: 416 AIECSL 421
Score = 49.3 bits (116), Expect = 2e-05
Identities = 28/127 (22%), Positives = 60/127 (47%), Gaps = 2/127 (1%)
Query: 270 VTEFKHPGDFYVQLYSSEVLEYMNQLSASLKETYANVHEKDYIPVKGEVCIAKYTVDQTW 329
V+ +HP F++Q+ S L+ +++L + + Y N +D G++ A + +W
Sbjct: 312 VSASEHPNHFWIQIVGSRSLQ-LDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSW 370
Query: 330 NRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCFVANVIPAEG 389
RA + ++ + ++D+G+ PL + L + P AI+C +A + P+
Sbjct: 371 YRARVLGT-LENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGD 429
Query: 390 NWSSDCI 396
W + +
Sbjct: 430 QWEEEAL 436
>gi|40255178 tudor domain containing 5 [Homo sapiens]
Length = 981
Score = 80.5 bits (197), Expect = 9e-15
Identities = 53/177 (29%), Positives = 83/177 (46%), Gaps = 10/177 (5%)
Query: 710 LGVDQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKL-------PNGFK 762
L + V V I SP +FY + D+ + L D+ + +L P F
Sbjct: 467 LDTSSLIGVFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECF- 525
Query: 763 AEIGQPCCAFFAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLP 822
+ G CC + D WYR ++ +L V+V + D+GNI V LR + + LP
Sbjct: 526 IQPGHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLP 585
Query: 823 FQGIRCQLADIQSRNKHWSEEAITRFQMCVAGIKLQARVVEVTENGI-GVELTDLST 878
Q I C LA ++ +HW+ +AI +FQ + G+K VV+ +GI + L D S+
Sbjct: 586 AQAIPCSLAWVRPVEEHWTSKAILQFQK-LCGLKPLVGVVDEYVDGILNIFLCDTSS 641
Score = 68.6 bits (166), Expect = 3e-11
Identities = 77/289 (26%), Positives = 120/289 (41%), Gaps = 34/289 (11%)
Query: 500 VAHIQTPEDFFCQ--QLQSGRKLAELQASLSK-YCDQLPPRSDFYPAI----GDICCAQF 552
V +I +P F+ + S L ++ + + Y +QL P G +CC +
Sbjct: 477 VEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCVRI 536
Query: 553 SEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAGV 612
SED WYR + ++ V V Y D+GN I+ L + +LP QAI C LA V
Sbjct: 537 SEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIPCSLAWV 596
Query: 613 KPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSL-VELIDKSETPHVSVSKVLLDAG 671
+P WT +AI +KL K + V VVD+ + L + L D S V VL G
Sbjct: 597 RPVEEHWTSKAILQFQKLCGLKPL-VGVVDEYVDGILNIFLCDTSSNEDVYFHHVLRTEG 655
Query: 672 FAVGEQSMVTDKPSDVKETSVPLGVEGKVNPLEWTWVELGVDQTVDVVVCVIYSPGEFYC 731
A+ + ++ K ++NPL G + D+V+ + P +
Sbjct: 656 HAIVCRENISSKGF------------SELNPLALYTTSSGGPE--DIVLTELGYPSQ--Q 699
Query: 732 HVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCC-AFFAGDGSW 779
H ED +K++ +K ++P G PC + GD W
Sbjct: 700 HYFNED--RKISPQSKESELRILDEIPT------GMPCLESVTIGDDIW 740
Score = 65.5 bits (158), Expect = 3e-10
Identities = 55/217 (25%), Positives = 102/217 (47%), Gaps = 18/217 (8%)
Query: 215 KLENKSSIETKDVEVN---NKSDCPLGVTKEIAIWAERIMFSDLRSLQLKKTMEIKGTVT 271
K+ K ++ K +++ NKS+ L + I + + L L T + G
Sbjct: 419 KICKKPNLVVKPLQLQVETNKSELNLAMANH-DIPPDAVPNKKLCRLPPLDTSSLIGVFV 477
Query: 272 EFK-HPGDFYVQLYSSEVLEYMNQLSASLKETYAN--VHEKDYIPV----KGEVCIAKYT 324
E+ P FY+++YS + E + + ++ Y+N V ++ +P G +C + +
Sbjct: 478 EYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCVRIS 537
Query: 325 VDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCFVANV 384
D+ W R II V +++++ V Y D+GN I+ + + L P AI C +A V
Sbjct: 538 EDKWWYRVIIHRV-LEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIPCSLAWV 596
Query: 385 IPAEGNWSSDCIKATKPLLMEQYCSIK-IVDILEEEV 420
P E +W+S I L ++ C +K +V +++E V
Sbjct: 597 RPVEEHWTSKAI-----LQFQKLCGLKPLVGVVDEYV 628
Score = 46.6 bits (109), Expect = 1e-04
Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Query: 994 GDACCAKYTSDDFWYRAVVLGTSDT-DVEVLYADYGNIETLPLCRVQPITSSHLALPFQI 1052
G CC + + D +WYR ++ + +VEV Y D+GNI + ++ + + LP Q
Sbjct: 529 GHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQA 588
Query: 1053 IRCSL 1057
I CSL
Sbjct: 589 IPCSL 593
>gi|77404397 staphylococcal nuclease domain containing 1 [Homo
sapiens]
Length = 910
Score = 57.8 bits (138), Expect = 6e-08
Identities = 37/95 (38%), Positives = 51/95 (53%), Gaps = 6/95 (6%)
Query: 270 VTEFKHPGDFYVQLYSSEVLEYMNQLSASLKETYANVH--EKDYIPVKGEVCIAKYTVDQ 327
VTE FYVQ E + +L +++ A+ E Y P +GE CIAK+ VD
Sbjct: 687 VTEITDDLHFYVQ--DVETGTQLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKF-VDG 743
Query: 328 TWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRI 362
W RA ++ V+ K HV YIDYGN E++P R+
Sbjct: 744 EWYRARVEKVE-SPAKIHVFYIDYGNREVLPSTRL 777
Score = 56.2 bits (134), Expect = 2e-07
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 4/117 (3%)
Query: 500 VAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDFY-PAIGDICCAQFSEDDQW 558
V I F+ Q +++G +L +L ++ PP Y P G+ C A+F D +W
Sbjct: 687 VTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKFV-DGEW 745
Query: 559 YRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLE--LPMQAIKCVLAGVK 613
YRA V S + V Y+DYGN E+L RL + P LP QA + A ++
Sbjct: 746 YRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQ 802
Score = 44.7 bits (104), Expect = 5e-04
Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Query: 740 KKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFFAGDGSWYRALVKEILPNGHVKVHFVD 799
K + ++ +A H + + G+ C A F DG WYRA V+++ + V ++D
Sbjct: 709 KLMENMRNDIASH--PPVEGSYAPRRGEFCIAKFV-DGEWYRARVEKVESPAKIHVFYID 765
Query: 800 YGNIEEVTADELRMISSTFLN--LPFQGIRCQLADIQ 834
YGN E + + L +S F LP Q A IQ
Sbjct: 766 YGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQ 802
Score = 43.5 bits (101), Expect = 0.001
Identities = 27/59 (45%), Positives = 31/59 (52%), Gaps = 6/59 (10%)
Query: 985 SRPP----YRPRIGDACCAKYTSDDFWYRAVVLGT-SDTDVEVLYADYGNIETLPLCRV 1038
S PP Y PR G+ C AK+ D WYRA V S + V Y DYGN E LP R+
Sbjct: 720 SHPPVEGSYAPRRGEFCIAKFV-DGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRL 777
>gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens]
Length = 903
Score = 57.4 bits (137), Expect = 8e-08
Identities = 46/171 (26%), Positives = 71/171 (41%), Gaps = 10/171 (5%)
Query: 706 TWVELGVDQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQK----LPNGF 761
+W+ L TV+V+V + G + L L++ + Q LP
Sbjct: 700 SWLMLPDGITVEVIVVNQVNAGHLFVQQHTHPTFHALRSLDQQMYLCYSQPGIPTLPTPV 759
Query: 762 KAEIGQPCCAFFAGDGSWYRA-LVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLN 820
+ + CA DG+W+RA +V V++ +VDYG + V D LR I S F+
Sbjct: 760 EITV---ICAAPGADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVT 816
Query: 821 LPFQGIRCQLADIQ--SRNKHWSEEAITRFQMCVAGIKLQARVVEVTENGI 869
LPFQG L + S + +S EA L A+V + G+
Sbjct: 817 LPFQGAEVLLDSVMPLSDDDQFSPEADAAMSEMTGNTALLAQVTSYSPTGL 867
Score = 45.4 bits (106), Expect = 3e-04
Identities = 37/139 (26%), Positives = 61/139 (43%), Gaps = 4/139 (2%)
Query: 547 ICCAQFSEDDQWYRASVLA-YASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAI 605
+ CA D W+RA V+A Y V + YVDYG ++ + + L I + LP Q
Sbjct: 763 VICAAPGADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGA 822
Query: 606 KCVLAGVKP--SLGIWTPEAICLMKKLVQNKIITVKVVDKLENS-SLVELIDKSETPHVS 662
+ +L V P ++PEA M ++ N + +V L++L V
Sbjct: 823 EVLLDSVMPLSDDDQFSPEADAAMSEMTGNTALLAQVTSYSPTGLPLIQLWSVVGDEVVL 882
Query: 663 VSKVLLDAGFAVGEQSMVT 681
+++ L++ G A S T
Sbjct: 883 INRSLVERGLAQWVDSYYT 901
Score = 40.8 bits (94), Expect = 0.008
Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 2/69 (2%)
Query: 998 CAKYTSDDFWYRAVVLGTSD--TDVEVLYADYGNIETLPLCRVQPITSSHLALPFQIIRC 1055
CA +D W+RA V+ + + +VE+ Y DYG + + + ++ I S + LPFQ
Sbjct: 765 CAAPGADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGAEV 824
Query: 1056 SLEGLMELN 1064
L+ +M L+
Sbjct: 825 LLDSVMPLS 833
>gi|170784859 serine/threonine kinase 31 isoform b [Homo sapiens]
Length = 996
Score = 57.4 bits (137), Expect = 8e-08
Identities = 54/179 (30%), Positives = 83/179 (46%), Gaps = 10/179 (5%)
Query: 499 VVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPP-RSDFYPAIGDICCAQFSEDDQ 557
V +HI+ F+ Q + + + ++ SLS+ C Q + P I FSED
Sbjct: 14 VGSHIEDAVTFWAQSINRNKDIMKIGCSLSEVCPQASSVLGNLDP--NKIYGGLFSEDQC 71
Query: 558 WYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAGVK-PSL 616
WYR VL S E LV Y+DYGN EIL+ + IP L+ A K L G+ PS
Sbjct: 72 WYRCKVLKIISVEKCLVRYIDYGNTEILNRSDIVE-IPLELQFSSVAKKYKLWGLHIPSD 130
Query: 617 GIWT--PEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPHVSVSKVLLDAGFA 673
T + + L+ K I +++ E+ + +I ++E V + + +L GFA
Sbjct: 131 QEVTQFDQGTTFLGSLIFEKEIKMRIKATSEDGT---VIAQAEYGSVDIGEEVLKKGFA 186
Score = 36.2 bits (82), Expect = 0.19
Identities = 32/141 (22%), Positives = 59/141 (41%), Gaps = 17/141 (12%)
Query: 713 DQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAF 772
D+ DVV I F+ + + K + + SL+E C Q + +
Sbjct: 8 DKVEDVVGSHIEDAVTFWAQSINRN--KDIMKIGCSLSEVCPQASSVLGNLDPNKIYGGL 65
Query: 773 FAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLAD 832
F+ D WYR V +I+ V ++DYGN E + ++ + +P + Q +
Sbjct: 66 FSEDQCWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDI-------VEIP---LELQFSS 115
Query: 833 IQSRNKHW-----SEEAITRF 848
+ + K W S++ +T+F
Sbjct: 116 VAKKYKLWGLHIPSDQEVTQF 136
>gi|14602443 serine/threonine kinase 31 isoform a [Homo sapiens]
Length = 1019
Score = 57.4 bits (137), Expect = 8e-08
Identities = 54/179 (30%), Positives = 83/179 (46%), Gaps = 10/179 (5%)
Query: 499 VVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPP-RSDFYPAIGDICCAQFSEDDQ 557
V +HI+ F+ Q + + + ++ SLS+ C Q + P I FSED
Sbjct: 37 VGSHIEDAVTFWAQSINRNKDIMKIGCSLSEVCPQASSVLGNLDP--NKIYGGLFSEDQC 94
Query: 558 WYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAGVK-PSL 616
WYR VL S E LV Y+DYGN EIL+ + IP L+ A K L G+ PS
Sbjct: 95 WYRCKVLKIISVEKCLVRYIDYGNTEILNRSDIVE-IPLELQFSSVAKKYKLWGLHIPSD 153
Query: 617 GIWT--PEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPHVSVSKVLLDAGFA 673
T + + L+ K I +++ E+ + +I ++E V + + +L GFA
Sbjct: 154 QEVTQFDQGTTFLGSLIFEKEIKMRIKATSEDGT---VIAQAEYGSVDIGEEVLKKGFA 209
Score = 36.2 bits (82), Expect = 0.19
Identities = 32/141 (22%), Positives = 59/141 (41%), Gaps = 17/141 (12%)
Query: 713 DQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAF 772
D+ DVV I F+ + + K + + SL+E C Q + +
Sbjct: 31 DKVEDVVGSHIEDAVTFWAQSINRN--KDIMKIGCSLSEVCPQASSVLGNLDPNKIYGGL 88
Query: 773 FAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLAD 832
F+ D WYR V +I+ V ++DYGN E + ++ + +P + Q +
Sbjct: 89 FSEDQCWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDI-------VEIP---LELQFSS 138
Query: 833 IQSRNKHW-----SEEAITRF 848
+ + K W S++ +T+F
Sbjct: 139 VAKKYKLWGLHIPSDQEVTQF 159
>gi|170784856 serine/threonine kinase 31 isoform b [Homo sapiens]
Length = 996
Score = 57.4 bits (137), Expect = 8e-08
Identities = 54/179 (30%), Positives = 83/179 (46%), Gaps = 10/179 (5%)
Query: 499 VVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPP-RSDFYPAIGDICCAQFSEDDQ 557
V +HI+ F+ Q + + + ++ SLS+ C Q + P I FSED
Sbjct: 14 VGSHIEDAVTFWAQSINRNKDIMKIGCSLSEVCPQASSVLGNLDP--NKIYGGLFSEDQC 71
Query: 558 WYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAGVK-PSL 616
WYR VL S E LV Y+DYGN EIL+ + IP L+ A K L G+ PS
Sbjct: 72 WYRCKVLKIISVEKCLVRYIDYGNTEILNRSDIVE-IPLELQFSSVAKKYKLWGLHIPSD 130
Query: 617 GIWT--PEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPHVSVSKVLLDAGFA 673
T + + L+ K I +++ E+ + +I ++E V + + +L GFA
Sbjct: 131 QEVTQFDQGTTFLGSLIFEKEIKMRIKATSEDGT---VIAQAEYGSVDIGEEVLKKGFA 186
Score = 36.2 bits (82), Expect = 0.19
Identities = 32/141 (22%), Positives = 59/141 (41%), Gaps = 17/141 (12%)
Query: 713 DQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAF 772
D+ DVV I F+ + + K + + SL+E C Q + +
Sbjct: 8 DKVEDVVGSHIEDAVTFWAQSINRN--KDIMKIGCSLSEVCPQASSVLGNLDPNKIYGGL 65
Query: 773 FAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLAD 832
F+ D WYR V +I+ V ++DYGN E + ++ + +P + Q +
Sbjct: 66 FSEDQCWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDI-------VEIP---LELQFSS 115
Query: 833 IQSRNKHW-----SEEAITRF 848
+ + K W S++ +T+F
Sbjct: 116 VAKKYKLWGLHIPSDQEVTQF 136
>gi|166851804 tudor domain containing 9 [Homo sapiens]
Length = 1382
Score = 55.1 bits (131), Expect = 4e-07
Identities = 60/213 (28%), Positives = 92/213 (43%), Gaps = 16/213 (7%)
Query: 688 KETSVPLGVEGKVNPLEWTWVELGVDQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNK 747
K+T P+ V + T +L + T+DV V G F+ + + E+ + L L
Sbjct: 876 KQTVDPMQVSFNTSDRSQTVTDLLL--TIDVTEVV--EVGHFWGYRIDENNSEILKKLTA 931
Query: 748 SLAEHCQQKLPNGFKAEIGQPCCAFFAGDGS--WYRALVKEILPNGHVKVHFVDYGNIEE 805
+ + LP ++ C A FA ++RA V + N +V FVDYGN
Sbjct: 932 EINQLTLVPLPTHPHPDL--VCLAPFADFDKQRYFRAQVLYVSGNS-AEVFFVDYGNKSH 988
Query: 806 VTADELRMISSTFLNLPFQGIRCQLADIQSR------NKHWSEEAITRFQMCVAGIKLQA 859
V L I FL LPFQ + ++ ++ KHWS+ A F V+G L
Sbjct: 989 VDLHLLMEIPCQFLELPFQALEFKICKMRPSAKSLVCGKHWSDGASQWFASLVSGCTLLV 1048
Query: 860 RVVEVTENGIGVELTDLSTCYPRI-ISDVLIDE 891
+V V + + V++ S I I DVLI +
Sbjct: 1049 KVFSVVHSVLHVDVYQYSGVQDAINIRDVLIQQ 1081
Score = 49.7 bits (117), Expect = 2e-05
Identities = 41/136 (30%), Positives = 66/136 (48%), Gaps = 10/136 (7%)
Query: 547 ICCAQFSEDDQ--WYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQA 604
+C A F++ D+ ++RA VL Y S S V +VDYGN + L L I + LELP QA
Sbjct: 950 VCLAPFADFDKQRYFRAQVL-YVSGNSAEVFFVDYGNKSHVDLHLLMEIPCQFLELPFQA 1008
Query: 605 IKCVLAGVKPSLGI------WTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSET 658
++ + ++PS W+ A LV + VKV + + V++ S
Sbjct: 1009 LEFKICKMRPSAKSLVCGKHWSDGASQWFASLVSGCTLLVKVFSVVHSVLHVDVYQYSGV 1068
Query: 659 PH-VSVSKVLLDAGFA 673
+++ VL+ G+A
Sbjct: 1069 QDAINIRDVLIQQGYA 1084
Score = 42.4 bits (98), Expect = 0.003
Identities = 35/117 (29%), Positives = 50/117 (42%), Gaps = 6/117 (5%)
Query: 939 DKTIQANVLEIISPNLFYALPKGMPENQEKLCMLTAELLEYCNAPKSRPPYRPRIGDACC 998
D + +V E++ F+ + N E L LTAE+ + P P P C
Sbjct: 897 DLLLTIDVTEVVEVGHFWGY-RIDENNSEILKKLTAEINQLTLVPL---PTHPHPDLVCL 952
Query: 999 AKYTSDDF--WYRAVVLGTSDTDVEVLYADYGNIETLPLCRVQPITSSHLALPFQII 1053
A + D ++RA VL S EV + DYGN + L + I L LPFQ +
Sbjct: 953 APFADFDKQRYFRAQVLYVSGNSAEVFFVDYGNKSHVDLHLLMEIPCQFLELPFQAL 1009
>gi|28461129 ankyrin repeat and MYND domain containing 2 [Homo
sapiens]
Length = 441
Score = 48.5 bits (114), Expect = 4e-05
Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 1/66 (1%)
Query: 170 CHRCGLFG-SLRCSQCKQTYYCSTACQRRDWSAHSIVCRPVQPNFHKLENKSSIETKDVE 228
C CG G S RCS CK YC CQ+ W H +C+ ++ + K + +++ E + E
Sbjct: 320 CTTCGEKGASKRCSVCKMVIYCDQTCQKTHWFTHKKICKNLKDIYEKQQLEAAKEKRQEE 379
Query: 229 VNNKSD 234
+ K D
Sbjct: 380 NHGKLD 385
>gi|188035871 SET and MYND domain containing 2 [Homo sapiens]
Length = 433
Score = 45.8 bits (107), Expect = 2e-04
Identities = 14/33 (42%), Positives = 21/33 (63%)
Query: 177 GSLRCSQCKQTYYCSTACQRRDWSAHSIVCRPV 209
G +C +CKQ +YC+ CQ+ DW H + C P+
Sbjct: 61 GLSKCGRCKQAFYCNVECQKEDWPMHKLECSPM 93
>gi|38016945 deformed epidermal autoregulatory factor 1 [Homo
sapiens]
Length = 565
Score = 45.4 bits (106), Expect = 3e-04
Identities = 16/41 (39%), Positives = 22/41 (53%)
Query: 166 RSTTCHRCGLFGSLRCSQCKQTYYCSTACQRRDWSAHSIVC 206
+ +C CG C+ C + YCST CQR+DW H +C
Sbjct: 500 KEQSCVNCGREAMSECTGCHKVNYCSTFCQRKDWKDHQHIC 540
>gi|239749940 PREDICTED: similar to deformed epidermal
autoregulatory factor 1 [Homo sapiens]
Length = 426
Score = 45.4 bits (106), Expect = 3e-04
Identities = 16/41 (39%), Positives = 22/41 (53%)
Query: 166 RSTTCHRCGLFGSLRCSQCKQTYYCSTACQRRDWSAHSIVC 206
+ +C CG C+ C + YCST CQR+DW H +C
Sbjct: 361 KEQSCVNCGREAMSECTGCHKVNYCSTFCQRKDWKDHQHIC 401
>gi|13489073 egl nine homolog 1 [Homo sapiens]
Length = 426
Score = 45.4 bits (106), Expect = 3e-04
Identities = 17/39 (43%), Positives = 25/39 (64%), Gaps = 1/39 (2%)
Query: 170 CHRCGLFGSL-RCSQCKQTYYCSTACQRRDWSAHSIVCR 207
C CG +L RCS+C+ ++YC QR+DW H +VC+
Sbjct: 21 CELCGKMENLLRCSRCRSSFYCCKEHQRQDWKKHKLVCQ 59
>gi|28872803 myeloid translocation gene on chromosome 16 isoform
MTG16a [Homo sapiens]
Length = 653
Score = 45.1 bits (105), Expect = 4e-04
Identities = 18/40 (45%), Positives = 20/40 (50%)
Query: 167 STTCHRCGLFGSLRCSQCKQTYYCSTACQRRDWSAHSIVC 206
S +C CG S CS C YC + CQ RDW H VC
Sbjct: 553 SESCWNCGRKASETCSGCNAARYCGSFCQHRDWEKHHHVC 592
>gi|28872805 myeloid translocation gene on chromosome 16 isoform
MTG16b [Homo sapiens]
Length = 567
Score = 45.1 bits (105), Expect = 4e-04
Identities = 18/40 (45%), Positives = 20/40 (50%)
Query: 167 STTCHRCGLFGSLRCSQCKQTYYCSTACQRRDWSAHSIVC 206
S +C CG S CS C YC + CQ RDW H VC
Sbjct: 467 SESCWNCGRKASETCSGCNAARYCGSFCQHRDWEKHHHVC 506
>gi|28329422 acute myelogenous leukemia 1 translocation 1 protein
isoform MTG8c [Homo sapiens]
Length = 567
Score = 43.5 bits (101), Expect = 0.001
Identities = 16/40 (40%), Positives = 20/40 (50%)
Query: 167 STTCHRCGLFGSLRCSQCKQTYYCSTACQRRDWSAHSIVC 206
S +C CG S CS C YC + CQ +DW H +C
Sbjct: 475 SESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHIC 514
>gi|28329419 acute myelogenous leukemia 1 translocation 1 protein
isoform MTG8c [Homo sapiens]
Length = 567
Score = 43.5 bits (101), Expect = 0.001
Identities = 16/40 (40%), Positives = 20/40 (50%)
Query: 167 STTCHRCGLFGSLRCSQCKQTYYCSTACQRRDWSAHSIVC 206
S +C CG S CS C YC + CQ +DW H +C
Sbjct: 475 SESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHIC 514
>gi|28329416 acute myelogenous leukemia 1 translocation 1 protein
isoform MTG8b [Homo sapiens]
Length = 604
Score = 43.5 bits (101), Expect = 0.001
Identities = 16/40 (40%), Positives = 20/40 (50%)
Query: 167 STTCHRCGLFGSLRCSQCKQTYYCSTACQRRDWSAHSIVC 206
S +C CG S CS C YC + CQ +DW H +C
Sbjct: 512 SESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHIC 551
>gi|4757916 acute myelogenous leukemia 1 translocation 1 protein
isoform MTG8a [Homo sapiens]
Length = 577
Score = 43.5 bits (101), Expect = 0.001
Identities = 16/40 (40%), Positives = 20/40 (50%)
Query: 167 STTCHRCGLFGSLRCSQCKQTYYCSTACQRRDWSAHSIVC 206
S +C CG S CS C YC + CQ +DW H +C
Sbjct: 485 SESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHIC 524
>gi|225703108 tudor domain containing 3 isoform 2 [Homo sapiens]
Length = 651
Score = 41.6 bits (96), Expect = 0.005
Identities = 21/50 (42%), Positives = 34/50 (68%), Gaps = 1/50 (2%)
Query: 545 GDICCAQFSEDDQWYRASVLA-YASEESVLVGYVDYGNFEILSLMRLCPI 593
GD C A + ED+++YRA V A ++S + +V ++DYGN+E + L + PI
Sbjct: 559 GDECFALYWEDNKFYRAEVEALHSSGMTAVVKFIDYGNYEEVLLSNIKPI 608
Score = 37.4 bits (85), Expect = 0.086
Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 2/50 (4%)
Query: 994 GDACCAKYTSDDFWYRAVV--LGTSDTDVEVLYADYGNIETLPLCRVQPI 1041
GD C A Y D+ +YRA V L +S V + DYGN E + L ++PI
Sbjct: 559 GDECFALYWEDNKFYRAEVEALHSSGMTAVVKFIDYGNYEEVLLSNIKPI 608
Score = 36.6 bits (83), Expect = 0.15
Identities = 19/52 (36%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
Query: 766 GQPCCAFFAGDGSWYRALVKEILPNGHVKV-HFVDYGNIEEVTADELRMISS 816
G C A + D +YRA V+ + +G V F+DYGN EEV ++ I +
Sbjct: 559 GDECFALYWEDNKFYRAEVEALHSSGMTAVVKFIDYGNYEEVLLSNIKPIQT 610
Score = 32.0 bits (71), Expect = 3.6
Identities = 17/47 (36%), Positives = 25/47 (53%)
Query: 316 GEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRI 362
G+ C A Y D + RA ++ + A V +IDYGN E + L+ I
Sbjct: 559 GDECFALYWEDNKFYRAEVEALHSSGMTAVVKFIDYGNYEEVLLSNI 605
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,605,884
Number of Sequences: 37866
Number of extensions: 2156378
Number of successful extensions: 6448
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 6088
Number of HSP's gapped (non-prelim): 207
length of query: 1189
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1076
effective length of database: 13,968,660
effective search space: 15030278160
effective search space used: 15030278160
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.