Guide to the Human Genome
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Search of human proteins with 12548785

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 1 [Homo sapiens]
         (512 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2 is...  1036   0.0  
gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2 iso...   937   0.0  
gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3 iso...   754   0.0  
gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1 p...   750   0.0  
gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3 is...   734   0.0  
gi|8924258 gamma-aminobutyric acid (GABA) receptor, theta precur...   370   e-102
gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta pre...   330   2e-90
gi|194097386 gamma-aminobutyric acid (GABA) receptor, rho 1 [Hom...   302   4e-82
gi|7657106 gamma-aminobutyric acid (GABA) A receptor, pi [Homo s...   299   4e-81
gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2 prec...   295   5e-80
gi|157743288 gamma-aminobutyric acid (GABA) receptor, rho 3 [Hom...   292   6e-79
gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens]       285   5e-77
gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform ...   282   6e-76
gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform ...   282   6e-76
gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens]       282   6e-76
gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens]         282   6e-76
gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens]       281   8e-76
gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens]       281   1e-75
gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo...   280   2e-75
gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo...   280   2e-75
gi|218156328 glycine receptor, alpha 4 precursor [Homo sapiens]       280   2e-75
gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precurso...   270   3e-72
gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precurso...   270   3e-72
gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3 ...   268   9e-72
gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo s...   262   5e-70
gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precurs...   262   5e-70
gi|189083762 gamma-aminobutyric acid A receptor, gamma 2 isoform...   260   2e-69
gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ...   259   3e-69
gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ...   259   3e-69
gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ...   259   3e-69

>gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2
           isoform 1 [Homo sapiens]
          Length = 512

 Score = 1036 bits (2680), Expect = 0.0
 Identities = 512/512 (100%), Positives = 512/512 (100%)

Query: 1   MWRVRKRGYFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPV 60
           MWRVRKRGYFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPV
Sbjct: 1   MWRVRKRGYFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPV 60

Query: 61  AVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDT 120
           AVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDT
Sbjct: 61  AVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDT 120

Query: 121 YFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES 180
           YFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES
Sbjct: 121 YFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES 180

Query: 181 YGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKR 240
           YGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKR
Sbjct: 181 YGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKR 240

Query: 241 NIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIP 300
           NIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIP
Sbjct: 241 NIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIP 300

Query: 301 YVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKI 360
           YVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKI
Sbjct: 301 YVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKI 360

Query: 361 FYKDIKQNGTQYRSLWDPTGNLSPTRRTTNYDFSLYTMDPHENILLSTLEIKNEMATSEA 420
           FYKDIKQNGTQYRSLWDPTGNLSPTRRTTNYDFSLYTMDPHENILLSTLEIKNEMATSEA
Sbjct: 361 FYKDIKQNGTQYRSLWDPTGNLSPTRRTTNYDFSLYTMDPHENILLSTLEIKNEMATSEA 420

Query: 421 VMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIPD 480
           VMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIPD
Sbjct: 421 VMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIPD 480

Query: 481 LTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN 512
           LTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN
Sbjct: 481 LTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN 512


>gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2
           isoform 2 [Homo sapiens]
          Length = 474

 Score =  937 bits (2421), Expect = 0.0
 Identities = 474/512 (92%), Positives = 474/512 (92%), Gaps = 38/512 (7%)

Query: 1   MWRVRKRGYFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPV 60
           MWRVRKRGYFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPV
Sbjct: 1   MWRVRKRGYFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPV 60

Query: 61  AVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDT 120
           AVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDT
Sbjct: 61  AVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDT 120

Query: 121 YFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES 180
           YFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES
Sbjct: 121 YFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES 180

Query: 181 YGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKR 240
           YGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKR
Sbjct: 181 YGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKR 240

Query: 241 NIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIP 300
           NIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIP
Sbjct: 241 NIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIP 300

Query: 301 YVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKI 360
           YVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNK 
Sbjct: 301 YVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNK- 359

Query: 361 FYKDIKQNGTQYRSLWDPTGNLSPTRRTTNYDFSLYTMDPHENILLSTLEIKNEMATSEA 420
                                                MDPHENILLSTLEIKNEMATSEA
Sbjct: 360 -------------------------------------MDPHENILLSTLEIKNEMATSEA 382

Query: 421 VMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIPD 480
           VMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIPD
Sbjct: 383 VMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIPD 442

Query: 481 LTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN 512
           LTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN
Sbjct: 443 LTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN 474


>gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3
           isoform 1 precursor [Homo sapiens]
          Length = 473

 Score =  754 bits (1947), Expect = 0.0
 Identities = 379/513 (73%), Positives = 420/513 (81%), Gaps = 41/513 (7%)

Query: 1   MWRVRKRGYFGIWSFPLIIAAVC-AQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPP 59
           MW +     FGI+S P+++A VC AQSVNDP NMS VKETVD+LLKGYDIRLRPDFGGPP
Sbjct: 1   MWGLAGGRLFGIFSAPVLVAVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPP 60

Query: 60  VAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPD 119
           V VGMNIDIASIDMVSEVNMDYTLTMYFQQ WRDKRL+Y+ IPLNLTLDNRVADQLWVPD
Sbjct: 61  VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPD 120

Query: 120 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE 179
           TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
Sbjct: 121 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE 180

Query: 180 SYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLK 239
           SYGYTTDDIEFYWRG D AVTGV +IELPQFSIV+++L+++ VVF+TG+YPRLSLSF+LK
Sbjct: 181 SYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLK 240

Query: 240 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI 299
           RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
Sbjct: 241 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI 300

Query: 300 PYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNK 359
           PYVKAIDMYLMGCFVFVF+ALLEYA VNYIFFGRGPQRQKK AEK A A N++ + + N+
Sbjct: 301 PYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNR 360

Query: 360 IFYKDIKQNGTQYRSLWDPTGNLSPTRRTTNYDFSLYTMDPHENILLSTLEIKNEMATSE 419
           +                                      D H NILL++LE+ NEM  +E
Sbjct: 361 V--------------------------------------DAHGNILLTSLEVHNEM--NE 380

Query: 420 AVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIP 479
              G+GD R++ +++D S IQYRK  +PR   GR   +R +  KK+ LRRR+SQLKI IP
Sbjct: 381 VSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIP 440

Query: 480 DLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN 512
           DLTDVNAIDRWSRI FP  FS FN+VYWLYYVN
Sbjct: 441 DLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN 473


>gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1
           precursor [Homo sapiens]
          Length = 474

 Score =  750 bits (1937), Expect = 0.0
 Identities = 376/513 (73%), Positives = 422/513 (82%), Gaps = 40/513 (7%)

Query: 1   MWRVRKRGYFGIWSFPLIIAAVC-AQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPP 59
           MW V+ R   G+ SFP++I  VC A S N+PSNMS VKETVDRLLKGYDIRLRPDFGGPP
Sbjct: 1   MWTVQNRESLGLLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPP 60

Query: 60  VAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPD 119
           V VGM ID+ASIDMVSEVNMDYTLTMYFQQ+W+DKRLSY+ IPLNLTLDNRVADQLWVPD
Sbjct: 61  VDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPD 120

Query: 120 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE 179
           TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
Sbjct: 121 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE 180

Query: 180 SYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLK 239
           SYGYTTDDIEFYW G + AVTGV KIELPQFSIVDYK+++KKV F+TG+YPRLSLSF+LK
Sbjct: 181 SYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLK 240

Query: 240 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI 299
           RNIGYFILQTYMPS LITILSWVSFWINYDASAARVALGITTVLTMTTI+THLRETLPKI
Sbjct: 241 RNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKI 300

Query: 300 PYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNK 359
           PYVKAID+YLMGCFVFVF+ALLEYA VNYIFFG+GP  QKK A K   + NEK +L++NK
Sbjct: 301 PYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGKGP--QKKGASKQDQSANEKNKLEMNK 358

Query: 360 IFYKDIKQNGTQYRSLWDPTGNLSPTRRTTNYDFSLYTMDPHENILLSTLEIKNEMATSE 419
           +                                     +D H NILLSTLEI+NE + SE
Sbjct: 359 V------------------------------------QVDAHGNILLSTLEIRNETSGSE 382

Query: 420 AVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIP 479
            +  + DP++TM +YD++SIQYRK    R ++GR AL+RH    K R+RRRASQLK+ IP
Sbjct: 383 VLTSVSDPKATMYSYDSASIQYRKPLSSREAYGR-ALDRHGVPSKGRIRRRASQLKVKIP 441

Query: 480 DLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN 512
           DLTDVN+ID+WSR+FFP+ FS FN+VYWLYYV+
Sbjct: 442 DLTDVNSIDKWSRMFFPITFSLFNVVYWLYYVH 474


>gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3
           isoform 2 precursor [Homo sapiens]
          Length = 473

 Score =  734 bits (1895), Expect = 0.0
 Identities = 367/488 (75%), Positives = 404/488 (82%), Gaps = 40/488 (8%)

Query: 25  QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLT 84
           +SVNDP NMS VKETVD+LLKGYDIRLRPDFGGPPV VGMNIDIASIDMVSEVNMDYTLT
Sbjct: 26  RSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLT 85

Query: 85  MYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHP 144
           MYFQQ WRDKRL+Y+ IPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHP
Sbjct: 86  MYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHP 145

Query: 145 DGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTK 204
           DGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRG D AVTGV +
Sbjct: 146 DGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVER 205

Query: 205 IELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSF 264
           IELPQFSIV+++L+++ VVF+TG+YPRLSLSF+LKRNIGYFILQTYMPSILITILSWVSF
Sbjct: 206 IELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSF 265

Query: 265 WINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYA 324
           WINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVF+ALLEYA
Sbjct: 266 WINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYA 325

Query: 325 LVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKIFYKDIKQNGTQYRSLWDPTGNLSP 384
            VNYIFFGRGPQRQKK AEK A A N++ + + N++                        
Sbjct: 326 FVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNRV------------------------ 361

Query: 385 TRRTTNYDFSLYTMDPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQYRKA 444
                         D H NILL++LE+ NEM  +E   G+GD R++ +++D S IQYRK 
Sbjct: 362 --------------DAHGNILLTSLEVHNEM--NEVSGGIGDTRNSAISFDNSGIQYRKQ 405

Query: 445 GLPRHSFGRNALERHVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNI 504
            +PR   GR   +R +  KK+ LRRR+SQLKI IPDLTDVNAIDRWSRI FP  FS FN+
Sbjct: 406 SMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNL 465

Query: 505 VYWLYYVN 512
           VYWLYYVN
Sbjct: 466 VYWLYYVN 473


>gi|8924258 gamma-aminobutyric acid (GABA) receptor, theta precursor
           [Homo sapiens]
          Length = 632

 Score =  370 bits (950), Expect = e-102
 Identities = 162/310 (52%), Positives = 239/310 (77%)

Query: 31  SNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQA 90
           +N ++V++ +DR+L  YD+RLRP+FGG PV V ++I + SI+ +SE+NMDYT+TM+F Q 
Sbjct: 54  ANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQT 113

Query: 91  WRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY 150
           W+D RL+Y    LNLTLD R+ ++LWVPD YFLN K +FVH VTV+NR+ +LHPDGTV Y
Sbjct: 114 WKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVRY 173

Query: 151 GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQF 210
           G+R+TTTAAC +DL ++P+D+Q C L +ESYGYT +DI  +W  + NA+    ++ +PQF
Sbjct: 174 GIRLTTTAACSLDLHKFPMDKQACNLVVESYGYTVEDIILFWDDNGNAIHMTEELHIPQF 233

Query: 211 SIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDA 270
           + +   + +K+V F TGSY RL L F+++R +  +++Q Y P++L TI SW+SFW+NYD+
Sbjct: 234 TFLGRTITSKEVYFYTGSYIRLILKFQVQREVNSYLVQVYWPTVLTTITSWISFWMNYDS 293

Query: 271 SAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIF 330
           SAARV +G+T++L +TTI++HLR+ LP I  +KAID+Y++ C  FVF++LLEY  +NY+F
Sbjct: 294 SAARVTIGLTSMLILTTIDSHLRDKLPNISCIKAIDIYILVCLFFVFLSLLEYVYINYLF 353

Query: 331 FGRGPQRQKK 340
           + RGP+RQ +
Sbjct: 354 YSRGPRRQPR 363



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 15/28 (53%), Positives = 21/28 (75%)

Query: 484 VNAIDRWSRIFFPVVFSFFNIVYWLYYV 511
           V  +D+WSR  FP+ F  FNIVYW+Y++
Sbjct: 604 VPKVDKWSRFLFPLAFGLFNIVYWVYHM 631


>gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta
           precursor [Homo sapiens]
          Length = 452

 Score =  330 bits (846), Expect = 2e-90
 Identities = 179/411 (43%), Positives = 257/411 (62%), Gaps = 21/411 (5%)

Query: 40  VDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYN 99
           +D L+ GY    RP  GGPPV V + +++ASID +SE NM+YT+T++  Q+WRD RLSYN
Sbjct: 44  LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103

Query: 100 VIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA 159
                L LD+R  D+LW+PDT+ +N K ++ H VTV+N++IRL PDG +LY +RIT+T A
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163

Query: 160 CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLIT 219
           C MDL +YP+DEQ C L++ESYGY+++DI +YW      + G+ K++L QF+I  Y+  T
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYRFTT 223

Query: 220 KKVVF-STGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALG 278
           + + F S G +PRLSL F L+RN G +I+Q+YMPS+L+  +SWVSFWI+  A  ARV+LG
Sbjct: 224 ELMNFKSAGQFPRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLG 283

Query: 279 ITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQ 338
           ITTVLTMTT+    R +LP+   +KA+D+Y   C+VFVF AL+EYA   +  F    +++
Sbjct: 284 ITTVLTMTTLMVSARSSLPRASAIKALDVYFWICYVFVFAALVEYA---FAHFNADYRKK 340

Query: 339 KKAAEKAASANNEKMRLDV-NKIFYKDIKQNGTQYRSLWDPTGNLSPTRRTTNYDFSLYT 397
           +KA  K +    E   +DV N I    +   G         T  L+ +RR      +L  
Sbjct: 341 QKAKVKVSRPRAE---MDVRNAIVLFSLSAAGV--------TQELAISRRQRRVPGNL-- 387

Query: 398 MDPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQ-YRKAGLP 447
           M  + ++ + T E K E A      G G  R+ +   DA +I  Y +A  P
Sbjct: 388 MGSYRSVGVETGETKKEGAARSG--GQGGIRARLRPIDADTIDIYARAVFP 436


>gi|194097386 gamma-aminobutyric acid (GABA) receptor, rho 1 [Homo
           sapiens]
          Length = 479

 Score =  302 bits (774), Expect = 4e-82
 Identities = 142/295 (48%), Positives = 210/295 (71%), Gaps = 2/295 (0%)

Query: 47  YDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSY-NVIPLNL 105
           +D  +RP FGGP + VG+++ + S+D +SEV+MD+T+T+Y +  W+D+RLS+ +   L++
Sbjct: 84  HDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNNLSM 143

Query: 106 TLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLR 165
           T D R+  ++WVPD +F++ K+SF+H  T  N M+R+ PDG VLY LR+T TA C MD  
Sbjct: 144 TFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFS 203

Query: 166 RYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVF- 224
           R+PLD Q C+LEIESY YT DD+  YW+  ++++    +I L QF I ++   TK   + 
Sbjct: 204 RFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYS 263

Query: 225 STGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLT 284
           STG Y RL ++F L+R+I +F+LQTY P+ L+ +LSWVSFWI+  A  ARV LGITTVLT
Sbjct: 264 STGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLT 323

Query: 285 MTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQK 339
           M+TI T +  ++P++ Y+KA+D+YL   FVFVF+++LEYA VNY+   +  + QK
Sbjct: 324 MSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKEQK 378



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 31/109 (28%), Positives = 54/109 (49%), Gaps = 8/109 (7%)

Query: 406 LSTLEIKNEMATSEAV---MGLGDPRSTMLA--YDASSIQYRKAGLPRHSF--GRNALER 458
           L+T++ + E    E +    GL  PR+ ML   Y    +      +P +     R  ++ 
Sbjct: 368 LTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKPDRMMVQL 427

Query: 459 HVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYW 507
            +A ++S  +R+ SQ    +    D +AID++SRI FP  +  FN++YW
Sbjct: 428 TLASERSSPQRK-SQRSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYW 475


>gi|7657106 gamma-aminobutyric acid (GABA) A receptor, pi [Homo
           sapiens]
          Length = 440

 Score =  299 bits (766), Expect = 4e-81
 Identities = 148/289 (51%), Positives = 202/289 (69%), Gaps = 2/289 (0%)

Query: 41  DRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNV 100
           + L  GY+  LRP+FGG PV + + +DIASI  +SE NMDYT T+Y +Q W D+RL +  
Sbjct: 42  ENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFEG 101

Query: 101 IPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAAC 160
              + TLD R+ + LWVPDTY +  KKSF+H VTV NR+IRL  +GTVLY LRITTT AC
Sbjct: 102 NK-SFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVAC 160

Query: 161 MMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITK 220
            MDL +YP+D Q C L++ES+GY  +D+EF W   +++V G+  + L Q++I  Y  +  
Sbjct: 161 NMDLSKYPMDTQTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERYFTLVT 220

Query: 221 KVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGIT 280
           +    TG+Y RL L F+L+RN+ YFIL+TY+PS  + +LSWVSFWI+ D+  AR  +G+T
Sbjct: 221 RSQQETGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVT 280

Query: 281 TVLTMTTINTHLRETLPKIP-YVKAIDMYLMGCFVFVFMALLEYALVNY 328
           TVL+MTT+    R +LP    ++KAID+YL  CF FVF ALLEYA+ +Y
Sbjct: 281 TVLSMTTLMIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHY 329



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 10/25 (40%), Positives = 18/25 (72%)

Query: 487 IDRWSRIFFPVVFSFFNIVYWLYYV 511
           +D +S++ FP++F   N+ YW YY+
Sbjct: 414 VDHYSKLLFPLIFMLANVFYWAYYM 438


>gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2
           precursor [Homo sapiens]
          Length = 490

 Score =  295 bits (756), Expect = 5e-80
 Identities = 140/300 (46%), Positives = 210/300 (70%), Gaps = 3/300 (1%)

Query: 47  YDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIP-LNL 105
           +D  +RP FGGP + VG+++ + S+D +SEV+MD+T+T+Y +  W+D+RL+++     ++
Sbjct: 89  HDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASNKSM 148

Query: 106 TLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLR 165
           T D R+  ++WVPD +F++ K+SF H  T  N M+R+ PDG VLY +RIT TA C MD  
Sbjct: 149 TFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFS 208

Query: 166 RYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFS 225
            +PLD Q C+LE+ESY YT +D+  YW+  D ++    KI L QF I  +   ++   +S
Sbjct: 209 HFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFYS 268

Query: 226 -TGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLT 284
            TG Y RL ++F L+R+I +F+LQTY P+ L+ +LSWVSFWI+  A  ARV+LGITTVLT
Sbjct: 269 STGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLT 328

Query: 285 MTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEK 344
           MTTI T +  ++P++ YVKA+D+YL   FVFVF+++LEYA VNY+   +  ++++K  EK
Sbjct: 329 MTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQ-ERKERKLREK 387



 Score = 38.1 bits (87), Expect = 0.019
 Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 12/100 (12%)

Query: 408 TLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRL 467
           T+ +    + SEA    G PRS +L  +      R+  +  H  G +  E + A+KK  L
Sbjct: 399 TMMLDGSYSESEANSLAGYPRSHILTEEE-----RQDKIVVH-LGLSG-EANAARKKGLL 451

Query: 468 RRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYW 507
           + +            + +AID++SR+ FP  + FFN++YW
Sbjct: 452 KGQTG-----FRIFQNTHAIDKYSRLIFPASYIFFNLIYW 486


>gi|157743288 gamma-aminobutyric acid (GABA) receptor, rho 3 [Homo
           sapiens]
          Length = 467

 Score =  292 bits (747), Expect = 6e-79
 Identities = 135/284 (47%), Positives = 203/284 (71%), Gaps = 2/284 (0%)

Query: 48  DIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSY-NVIPLNLT 106
           D  +RP FGG PV VG+++ + SID +SE NMD+T+T Y +  W+D+RLS+ +    ++T
Sbjct: 71  DFAMRPGFGGSPVPVGIDVHVESIDSISETNMDFTMTFYLRHYWKDERLSFPSTANKSMT 130

Query: 107 LDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRR 166
            D+R+  ++WVPD +F++ K+SF+H  T++N M+R+HPDG VL  LRIT +A C MD  R
Sbjct: 131 FDHRLTRKIWVPDIFFVHSKRSFIHDTTMENIMLRVHPDGNVLLSLRITVSAMCFMDFSR 190

Query: 167 YPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVF-S 225
           +PLD QNC+LE+ESY Y  DD+  YW+  + ++     + L QF I D+   +    + S
Sbjct: 191 FPLDTQNCSLELESYAYNEDDLMLYWKHGNKSLNTEEHMSLSQFFIEDFSASSGLAFYSS 250

Query: 226 TGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTM 285
           TG Y RL ++F L+R++ +F+LQTY P+IL+ +LSWVSFWI+  A  ARV+LGITTVLTM
Sbjct: 251 TGWYNRLFINFVLRRHVFFFVLQTYFPAILMVMLSWVSFWIDRRAVPARVSLGITTVLTM 310

Query: 286 TTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYI 329
           +TI T +  ++P++ Y+KA+D+YL    +FVF++++EYA VNY+
Sbjct: 311 STIITAVSASMPQVSYLKAVDVYLWVSSLFVFLSVIEYAAVNYL 354



 Score = 37.0 bits (84), Expect = 0.043
 Identities = 15/31 (48%), Positives = 21/31 (67%)

Query: 481 LTDVNAIDRWSRIFFPVVFSFFNIVYWLYYV 511
           L + + ID +SRI FP+V+  FN+ YW  YV
Sbjct: 437 LENNHVIDTYSRILFPIVYILFNLFYWGVYV 467


>gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens]
          Length = 464

 Score =  285 bits (730), Expect = 5e-77
 Identities = 176/511 (34%), Positives = 258/511 (50%), Gaps = 83/511 (16%)

Query: 10  FGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLK------GYDIRLRPDFGGPPVAVG 63
           F  W   L+++ V  +  +   + S      D L K      GYD R+RP+F GPPV V 
Sbjct: 14  FYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVT 73

Query: 64  MNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLN-LTLDNRVADQLWVPDTYF 122
            NI I S   ++E  MDY + ++ +Q W D RL+Y+  P + L LD  + D +W PD +F
Sbjct: 74  CNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFF 133

Query: 123 LNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYG 182
            N+K +  H VT  N+++R+  +G VLY +R+T T +C MDL+ +P+D Q C +++ES+G
Sbjct: 134 ANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFG 193

Query: 183 YTTDDIEFYWRGDDNAVTGVTKIELPQFSIV---DYKLITKKVVFSTGSYPRLSLSFKLK 239
           YT +D+ F W+ D+  V     + LPQF +    D +  TK   ++TG +  + + F L+
Sbjct: 194 YTMNDLIFEWQ-DEAPVQVAEGLTLPQFLLKEEKDLRYCTKH--YNTGKFTCIEVRFHLE 250

Query: 240 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI 299
           R +GY+++Q Y+PS+LI ILSWVSFWIN DA+ ARVALGITTVLTMTT ++  R +LPK+
Sbjct: 251 RQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKV 310

Query: 300 PYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNK 359
            YVKAID+++  C +FVF ALLEYA VN++       RQ K   +       K      +
Sbjct: 311 SYVKAIDIWMAVCLLFVFSALLEYAAVNFV------SRQHKELLRFRRKRKNKTEAFALE 364

Query: 360 IFYKDIKQNGTQYRSLWDPTGNLSPTRRTTNYDFSLYTMDPHENILLSTLEIKNEMATSE 419
            FY+                 ++    R + + F+ Y M P        L+ K+ M    
Sbjct: 365 KFYR---------------FSDMDDEVRESRFSFTAYGMGP-------CLQAKDGMTPK- 401

Query: 420 AVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIP 479
                  P   +     S  + RK  + R                               
Sbjct: 402 ------GPNHPVQVMPKSPDEMRKVFIDR------------------------------- 424

Query: 480 DLTDVNAIDRWSRIFFPVVFSFFNIVYWLYY 510
                  ID  SR  FP+ F  FNI YW+ Y
Sbjct: 425 ----AKKIDTISRACFPLAFLIFNIFYWVIY 451


>gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform 2
           precursor [Homo sapiens]
          Length = 467

 Score =  282 bits (721), Expect = 6e-76
 Identities = 134/305 (43%), Positives = 196/305 (64%)

Query: 40  VDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYN 99
           ++ LL+GYD +LRPD G  P  +  ++ + SI  V+ +NM+YT+ ++F Q W D+RL +N
Sbjct: 70  LNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFN 129

Query: 100 VIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA 159
                L L++ +  ++W+PDT+F N KK+  H +T  NRM+R+  DG VLY LR+T  A 
Sbjct: 130 STIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAE 189

Query: 160 CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLIT 219
           C + L  +P+DE +C LE  SYGY  ++I + W+     V       L QFS V  +  T
Sbjct: 190 CQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTT 249

Query: 220 KKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 279
           + V  ++G Y  +S+ F L R +GYF +QTY+P  LI +LSWVSFWIN DA  AR +LGI
Sbjct: 250 EVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGI 309

Query: 280 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQK 339
           TTVLTMTT++T  R++LPK+ YV A+D+++  CF+FVF AL+EY  ++Y    R P + K
Sbjct: 310 TTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDK 369

Query: 340 KAAEK 344
              +K
Sbjct: 370 DKKKK 374



 Score = 37.4 bits (85), Expect = 0.033
 Identities = 13/25 (52%), Positives = 19/25 (76%)

Query: 487 IDRWSRIFFPVVFSFFNIVYWLYYV 511
           +D ++RIFFP  F  FN+VYW+ Y+
Sbjct: 441 MDSYARIFFPTAFCLFNLVYWVSYL 465


>gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform 1
           precursor [Homo sapiens]
          Length = 475

 Score =  282 bits (721), Expect = 6e-76
 Identities = 134/305 (43%), Positives = 196/305 (64%)

Query: 40  VDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYN 99
           ++ LL+GYD +LRPD G  P  +  ++ + SI  V+ +NM+YT+ ++F Q W D+RL +N
Sbjct: 70  LNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFN 129

Query: 100 VIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA 159
                L L++ +  ++W+PDT+F N KK+  H +T  NRM+R+  DG VLY LR+T  A 
Sbjct: 130 STIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAE 189

Query: 160 CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLIT 219
           C + L  +P+DE +C LE  SYGY  ++I + W+     V       L QFS V  +  T
Sbjct: 190 CQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTT 249

Query: 220 KKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 279
           + V  ++G Y  +S+ F L R +GYF +QTY+P  LI +LSWVSFWIN DA  AR +LGI
Sbjct: 250 EVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGI 309

Query: 280 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQK 339
           TTVLTMTT++T  R++LPK+ YV A+D+++  CF+FVF AL+EY  ++Y    R P + K
Sbjct: 310 TTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDK 369

Query: 340 KAAEK 344
              +K
Sbjct: 370 DKKKK 374



 Score = 37.4 bits (85), Expect = 0.033
 Identities = 13/25 (52%), Positives = 19/25 (76%)

Query: 487 IDRWSRIFFPVVFSFFNIVYWLYYV 511
           +D ++RIFFP  F  FN+VYW+ Y+
Sbjct: 449 MDSYARIFFPTAFCLFNLVYWVSYL 473


>gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens]
          Length = 452

 Score =  282 bits (721), Expect = 6e-76
 Identities = 148/329 (44%), Positives = 215/329 (65%), Gaps = 15/329 (4%)

Query: 24  AQSVNDPSNMSLVKETVDRLL---KGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMD 80
           ++S   PS      + +D+L+    GYD R+RP+F GPPV V  NI I S   V+E  MD
Sbjct: 32  SRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMD 91

Query: 81  YTLTMYFQQAWRDKRLSYNVIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 139
           Y + ++ +Q W D RL+Y+  P + L LD  + D +W PD +F N+K +  H VT  N++
Sbjct: 92  YRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKL 151

Query: 140 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAV 199
           +R+  +G VLY +R+T T +C MDL+ +P+D Q CT+++ES+GYT +D+ F W  D   V
Sbjct: 152 LRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSD-GPV 210

Query: 200 TGVTKIELPQFSIVDYKLI---TKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILI 256
                + LPQF + + K +   TK   ++TG +  + + F L+R +GY+++Q Y+PS+LI
Sbjct: 211 QVAEGLTLPQFILKEEKELGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLI 268

Query: 257 TILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFV 316
            ILSWVSFWIN DA+ ARVALGITTVLTMTT ++  R +LPK+ YVKAID+++  C +FV
Sbjct: 269 VILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFV 328

Query: 317 FMALLEYALVNYIF-----FGRGPQRQKK 340
           F ALLEYA VN++      F R  +RQK+
Sbjct: 329 FAALLEYAAVNFVSRQHKEFLRLRRRQKR 357



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 13/24 (54%), Positives = 15/24 (62%)

Query: 487 IDRWSRIFFPVVFSFFNIVYWLYY 510
           ID  SR  FP+ F  FNI YW+ Y
Sbjct: 418 IDTISRAAFPLAFLIFNIFYWITY 441


>gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens]
          Length = 452

 Score =  282 bits (721), Expect = 6e-76
 Identities = 148/329 (44%), Positives = 215/329 (65%), Gaps = 15/329 (4%)

Query: 24  AQSVNDPSNMSLVKETVDRLL---KGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMD 80
           ++S   PS      + +D+L+    GYD R+RP+F GPPV V  NI I S   V+E  MD
Sbjct: 32  SRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMD 91

Query: 81  YTLTMYFQQAWRDKRLSYNVIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 139
           Y + ++ +Q W D RL+Y+  P + L LD  + D +W PD +F N+K +  H VT  N++
Sbjct: 92  YRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKL 151

Query: 140 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAV 199
           +R+  +G VLY +R+T T +C MDL+ +P+D Q CT+++ES+GYT +D+ F W  D   V
Sbjct: 152 LRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSD-GPV 210

Query: 200 TGVTKIELPQFSIVDYKLI---TKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILI 256
                + LPQF + + K +   TK   ++TG +  + + F L+R +GY+++Q Y+PS+LI
Sbjct: 211 QVAEGLTLPQFILKEEKELGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLI 268

Query: 257 TILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFV 316
            ILSWVSFWIN DA+ ARVALGITTVLTMTT ++  R +LPK+ YVKAID+++  C +FV
Sbjct: 269 VILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFV 328

Query: 317 FMALLEYALVNYIF-----FGRGPQRQKK 340
           F ALLEYA VN++      F R  +RQK+
Sbjct: 329 FAALLEYAAVNFVSRQHKEFLRLRRRQKR 357



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 13/24 (54%), Positives = 15/24 (62%)

Query: 487 IDRWSRIFFPVVFSFFNIVYWLYY 510
           ID  SR  FP+ F  FNI YW+ Y
Sbjct: 418 IDTISRAAFPLAFLIFNIFYWITY 441


>gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens]
          Length = 452

 Score =  281 bits (720), Expect = 8e-76
 Identities = 147/329 (44%), Positives = 215/329 (65%), Gaps = 15/329 (4%)

Query: 24  AQSVNDPSNMSLVKETVDRLL---KGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMD 80
           ++S   PS      + +D+L+    GYD R+RP+F GPPV V  NI I S   ++E  MD
Sbjct: 32  SRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMD 91

Query: 81  YTLTMYFQQAWRDKRLSYNVIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 139
           Y + ++ +Q W D RL+Y+  P + L LD  + D +W PD +F N+K +  H VT  N++
Sbjct: 92  YRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKL 151

Query: 140 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAV 199
           +R+  +G VLY +R+T T +C MDL+ +P+D Q CT+++ES+GYT +D+ F W  D   V
Sbjct: 152 LRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSD-GPV 210

Query: 200 TGVTKIELPQFSIVDYKLI---TKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILI 256
                + LPQF + + K +   TK   ++TG +  + + F L+R +GY+++Q Y+PS+LI
Sbjct: 211 QVAEGLTLPQFILKEEKELGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLI 268

Query: 257 TILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFV 316
            ILSWVSFWIN DA+ ARVALGITTVLTMTT ++  R +LPK+ YVKAID+++  C +FV
Sbjct: 269 VILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFV 328

Query: 317 FMALLEYALVNYIF-----FGRGPQRQKK 340
           F ALLEYA VN++      F R  +RQK+
Sbjct: 329 FAALLEYAAVNFVSRQHKEFLRLRRRQKR 357



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 13/24 (54%), Positives = 15/24 (62%)

Query: 487 IDRWSRIFFPVVFSFFNIVYWLYY 510
           ID  SR  FP+ F  FNI YW+ Y
Sbjct: 418 IDTISRAAFPLAFLIFNIFYWITY 441


>gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens]
          Length = 449

 Score =  281 bits (718), Expect = 1e-75
 Identities = 144/330 (43%), Positives = 211/330 (63%), Gaps = 13/330 (3%)

Query: 10  FGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLK------GYDIRLRPDFGGPPVAVG 63
           F  W   L+++ V  +  +   + S      D L K      GYD R+RP+F GPPV V 
Sbjct: 14  FYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVT 73

Query: 64  MNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLN-LTLDNRVADQLWVPDTYF 122
            NI I S   ++E  MDY + ++ +Q W D RL+Y+  P + L LD  + D +W PD +F
Sbjct: 74  CNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFF 133

Query: 123 LNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYG 182
            N+K +  H VT  N+++R+  +G VLY +R+T T +C MDL+ +P+D Q C +++ES+G
Sbjct: 134 ANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFG 193

Query: 183 YTTDDIEFYWRGDDNAVTGVTKIELPQFSIV---DYKLITKKVVFSTGSYPRLSLSFKLK 239
           YT +D+ F W+ D+  V     + LPQF +    D +  TK   ++TG +  + + F L+
Sbjct: 194 YTMNDLIFEWQ-DEAPVQVAEGLTLPQFLLKEEKDLRYCTKH--YNTGKFTCIEVRFHLE 250

Query: 240 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI 299
           R +GY+++Q Y+PS+LI ILSWVSFWIN DA+ ARVALGITTVLTMTT ++  R +LPK+
Sbjct: 251 RQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKV 310

Query: 300 PYVKAIDMYLMGCFVFVFMALLEYALVNYI 329
            YVKAID+++  C +FVF ALLEYA VN++
Sbjct: 311 SYVKAIDIWMAVCLLFVFSALLEYAAVNFV 340



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 13/24 (54%), Positives = 15/24 (62%)

Query: 487 IDRWSRIFFPVVFSFFNIVYWLYY 510
           ID  SR  FP+ F  FNI YW+ Y
Sbjct: 413 IDTISRACFPLAFLIFNIFYWVIY 436


>gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 457

 Score =  280 bits (717), Expect = 2e-75
 Identities = 141/313 (45%), Positives = 204/313 (65%), Gaps = 7/313 (2%)

Query: 21  AVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMD 80
           A  A+S   P + S   + +     GYD R+RP+F GPPV V  NI I S   ++E  MD
Sbjct: 26  AEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMD 85

Query: 81  YTLTMYFQQAWRDKRLSYNVIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 139
           Y + ++ +Q W D RL+YN  P + L LD  + D +W PD +F N+K +  H +T  N++
Sbjct: 86  YRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKL 145

Query: 140 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAV 199
           +R+  +G VLY +RIT T AC MDL+ +P+D Q C +++ES+GYT +D+ F W+ +  AV
Sbjct: 146 LRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQ-EQGAV 204

Query: 200 TGVTKIELPQFSIV---DYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILI 256
                + LPQF +    D +  TK   ++TG +  +   F L+R +GY+++Q Y+PS+LI
Sbjct: 205 QVADGLTLPQFILKEEKDLRYCTKH--YNTGKFTCIEARFHLERQMGYYLIQMYIPSLLI 262

Query: 257 TILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFV 316
            ILSW+SFWIN DA+ ARV LGITTVLTMTT ++  R +LPK+ YVKAID+++  C +FV
Sbjct: 263 VILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFV 322

Query: 317 FMALLEYALVNYI 329
           F ALLEYA VN++
Sbjct: 323 FSALLEYAAVNFV 335



 Score = 33.5 bits (75), Expect = 0.47
 Identities = 13/24 (54%), Positives = 17/24 (70%)

Query: 487 IDRWSRIFFPVVFSFFNIVYWLYY 510
           ID+ SRI FP+ F  FN+ YW+ Y
Sbjct: 423 IDKISRIGFPMAFLIFNMFYWIIY 446


>gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 449

 Score =  280 bits (717), Expect = 2e-75
 Identities = 141/313 (45%), Positives = 204/313 (65%), Gaps = 7/313 (2%)

Query: 21  AVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMD 80
           A  A+S   P + S   + +     GYD R+RP+F GPPV V  NI I S   ++E  MD
Sbjct: 26  AEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMD 85

Query: 81  YTLTMYFQQAWRDKRLSYNVIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 139
           Y + ++ +Q W D RL+YN  P + L LD  + D +W PD +F N+K +  H +T  N++
Sbjct: 86  YRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKL 145

Query: 140 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAV 199
           +R+  +G VLY +RIT T AC MDL+ +P+D Q C +++ES+GYT +D+ F W+ +  AV
Sbjct: 146 LRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQ-EQGAV 204

Query: 200 TGVTKIELPQFSIV---DYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILI 256
                + LPQF +    D +  TK   ++TG +  +   F L+R +GY+++Q Y+PS+LI
Sbjct: 205 QVADGLTLPQFILKEEKDLRYCTKH--YNTGKFTCIEARFHLERQMGYYLIQMYIPSLLI 262

Query: 257 TILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFV 316
            ILSW+SFWIN DA+ ARV LGITTVLTMTT ++  R +LPK+ YVKAID+++  C +FV
Sbjct: 263 VILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFV 322

Query: 317 FMALLEYALVNYI 329
           F ALLEYA VN++
Sbjct: 323 FSALLEYAAVNFV 335



 Score = 33.5 bits (75), Expect = 0.47
 Identities = 13/24 (54%), Positives = 17/24 (70%)

Query: 487 IDRWSRIFFPVVFSFFNIVYWLYY 510
           ID+ SRI FP+ F  FN+ YW+ Y
Sbjct: 415 IDKISRIGFPMAFLIFNMFYWIIY 438


>gi|218156328 glycine receptor, alpha 4 precursor [Homo sapiens]
          Length = 417

 Score =  280 bits (716), Expect = 2e-75
 Identities = 145/331 (43%), Positives = 210/331 (63%), Gaps = 15/331 (4%)

Query: 12  IWSFP---LIIAAVCAQSVNDPSNMSLVKETVDRLLK------GYDIRLRPDFGGPPVAV 62
           +W+ P   L+  A+  + V   +  S      D L K      GYD R+RP+F GPPV V
Sbjct: 14  LWTLPGQVLLRVALAKEEVKSGTKGSQPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNV 73

Query: 63  GMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLN-LTLDNRVADQLWVPDTY 121
             NI I S   +++  MDY + ++ +Q W D RLSY   P + L LD  + D +W PD +
Sbjct: 74  TCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSIWKPDLF 133

Query: 122 FLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESY 181
           F N+K +  H VT  N+++R+  +G VLY +R+T   +C+MDL+ +P+D Q CT+++ES+
Sbjct: 134 FANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCTMQLESF 193

Query: 182 GYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLI---TKKVVFSTGSYPRLSLSFKL 238
           GYT  D+ F W  D  AV     + LPQF + D K +   TK   ++TG +  + + F L
Sbjct: 194 GYTMKDLVFEWLEDAPAVQVAEGLTLPQFILRDEKDLGCCTKH--YNTGKFTCIEVKFHL 251

Query: 239 KRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPK 298
           +R +GY+++Q Y+PS+LI ILSWVSFWIN DA+ ARV LGITTVLTMTT ++  R +LPK
Sbjct: 252 ERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPK 311

Query: 299 IPYVKAIDMYLMGCFVFVFMALLEYALVNYI 329
           + YVKAID+++  C +FVF ALLEYA +N++
Sbjct: 312 VSYVKAIDIWMAVCLLFVFAALLEYAAINFV 342


>gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precursor
           [Homo sapiens]
          Length = 465

 Score =  270 bits (689), Expect = 3e-72
 Identities = 131/314 (41%), Positives = 196/314 (62%), Gaps = 3/314 (0%)

Query: 36  VKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKR 95
           + + ++ LL+GYD +LRPD G  P  +  ++ + SI  V  +NM+YT+ + F Q W D R
Sbjct: 64  ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSR 123

Query: 96  LSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRIT 155
           L +N     L L++ +  ++W+PDT+F N +KS  H +T  NR++R+  DG VLY LR+T
Sbjct: 124 LKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLT 183

Query: 156 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDY 215
             A C + L  +P+DE +C LE  SYGY  ++IE+ W+     V       L QF+ V  
Sbjct: 184 INAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGL 243

Query: 216 KLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARV 275
           +  T+     +G Y  +++ F L R +GYF +QTY+P IL  +LSWVSFWIN DA  AR 
Sbjct: 244 RNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPART 303

Query: 276 ALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFF---G 332
           +LGITTVLTMTT++T  R++LPK+ YV A+D+++  CF+FVF AL+EY  ++Y      G
Sbjct: 304 SLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNQKG 363

Query: 333 RGPQRQKKAAEKAA 346
           +   + +K   KA+
Sbjct: 364 KTATKDRKLKNKAS 377



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 15/25 (60%), Positives = 20/25 (80%)

Query: 487 IDRWSRIFFPVVFSFFNIVYWLYYV 511
           ID +SRIFFP  F+ FN+VYW+ Y+
Sbjct: 439 IDSYSRIFFPTAFALFNLVYWVGYL 463


>gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precursor
           [Homo sapiens]
          Length = 554

 Score =  270 bits (689), Expect = 3e-72
 Identities = 169/511 (33%), Positives = 259/511 (50%), Gaps = 57/511 (11%)

Query: 40  VDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYN 99
           +D LL GYD RLRP FGGP   V  +I + S   VS+V M+YT+ ++F+Q W DKRL Y+
Sbjct: 52  LDSLLDGYDNRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKYD 111

Query: 100 VIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA 159
                L L+N +  ++W PDT+F N KKS  H +T  N++ R+  +GT+LY +R+T +A 
Sbjct: 112 GPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISAE 171

Query: 160 CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTK--IELPQFSIVDYKL 217
           C M L  +P+D   C L+  SY Y   ++ + W         V K    L Q+ ++   +
Sbjct: 172 CPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLIGQTV 231

Query: 218 ITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVAL 277
            ++ +   TG Y  +++ F L+R +GYF++QTY+P I+  ILS VSFWIN ++  AR   
Sbjct: 232 SSETIKSITGEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVF 291

Query: 278 GITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQR 337
           GITTVLTMTT++   R +LPK+ Y  A+D ++  CF FVF AL+E+A VNY        +
Sbjct: 292 GITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYF----TNIQ 347

Query: 338 QKKAAEKAASANNEKMRLDVNKIFYKDIKQNGTQYRSLWDPTGNLSPTRRTTNYDFSLYT 397
            +KA  K +    E     V +  + +     T          NL+  +RT     S   
Sbjct: 348 MEKAKRKTSKPPQEVPAAPVQREKHPEAPLQNT--------NANLNMRKRTNALVHS--- 396

Query: 398 MDPHENILLSTLEIKNEMATSEAVM---GLGDPRSTMLAY-------------------- 434
               E+ + +  E+ N  + S  V+     G PRS + +                     
Sbjct: 397 ----ESDVGNRTEVGNHSSKSSTVVQESSKGTPRSYLASSPNPFSRANAAETISAARALP 452

Query: 435 DASSIQYRKAGLPRHSFGRNALERHV-AQKKSRLRRRASQLKIT------------IPDL 481
            AS    R   +PR +   +A  RHV   +  R++   + +  T             P  
Sbjct: 453 SASPTSIRTGYMPRKASVGSASTRHVFGSRLQRIKTTVNTIGATGKLSATPPPSAPPPSG 512

Query: 482 TDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN 512
           +  + ID+++RI FPV F  FN+VYW+ Y++
Sbjct: 513 SGTSKIDKYARILFPVTFGAFNMVYWVVYLS 543


>gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3
           [Homo sapiens]
          Length = 467

 Score =  268 bits (685), Expect = 9e-72
 Identities = 128/301 (42%), Positives = 190/301 (63%)

Query: 40  VDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYN 99
           +++LL+ YD +LRPD G  P  + ++I + SI  VS +NM+Y + ++F Q W D RL +N
Sbjct: 51  LNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFN 110

Query: 100 VIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA 159
                LTL++ +   +W+PDT F N K +  H +T  N+++R+  DG +LY LR+T  A 
Sbjct: 111 STMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAE 170

Query: 160 CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLIT 219
           C + L  +P+DE +C L   SYGY  +++ + WR +           L QF  +  +  T
Sbjct: 171 CQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNTT 230

Query: 220 KKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 279
           + V  S G Y  +++ F+L R +GYF +QTY+P IL  +LSWVSFWI  DA+ AR ALGI
Sbjct: 231 EIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGI 290

Query: 280 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQK 339
           TTVLTMTT++T  R++LP++ YV A+D+++  CF+FVF AL+EYA +NY    R P   K
Sbjct: 291 TTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTTTK 350

Query: 340 K 340
           K
Sbjct: 351 K 351



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 14/29 (48%), Positives = 21/29 (72%)

Query: 483 DVNAIDRWSRIFFPVVFSFFNIVYWLYYV 511
           D+  +D +SR+FFP  F  FN+VYW+ Y+
Sbjct: 437 DILELDSYSRVFFPTSFLLFNLVYWVGYL 465


>gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo
           sapiens]
          Length = 451

 Score =  262 bits (670), Expect = 5e-70
 Identities = 132/328 (40%), Positives = 199/328 (60%), Gaps = 6/328 (1%)

Query: 10  FGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIA 69
           F +W  P  +     Q     +N+++    +DRLL GYD RLRP  G     V  NI + 
Sbjct: 17  FLVWD-PARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVT 75

Query: 70  SIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLN-LTLDNRVADQLWVPDTYFLNDKKS 128
           S   VS+ +M+YT+ ++F+Q W+D+RL +   P+N L L+N +A ++W PDT+F N KKS
Sbjct: 76  SFGPVSDTDMEYTIDVFFRQKWKDERLKFKG-PMNILRLNNLMASKIWTPDTFFHNGKKS 134

Query: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
             H +T+ N+++R+  DGT+LY +R+T  A C M L  +P+D  +C L+  SY YTT ++
Sbjct: 135 VAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEV 194

Query: 189 EFYW--RGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFI 246
            + W     D+         L Q+ ++   +  + +  STG Y  ++  F LKR IGYF+
Sbjct: 195 TYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFV 254

Query: 247 LQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAID 306
           +QTY+P I+  ILS VSFW+N ++  AR   G+TTVLTMTT++   R +LPK+ Y  A+D
Sbjct: 255 IQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMD 314

Query: 307 MYLMGCFVFVFMALLEYALVNYIFFGRG 334
            ++  C+ FVF AL+E+A VNY F  RG
Sbjct: 315 WFIAVCYAFVFSALIEFATVNY-FTKRG 341



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 18/29 (62%), Positives = 22/29 (75%)

Query: 484 VNAIDRWSRIFFPVVFSFFNIVYWLYYVN 512
           V+ IDR SRI FPV+F  FN+VYW  Y+N
Sbjct: 414 VSKIDRMSRIVFPVLFGTFNLVYWATYLN 442


>gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precursor
           [Homo sapiens]
          Length = 451

 Score =  262 bits (670), Expect = 5e-70
 Identities = 132/328 (40%), Positives = 199/328 (60%), Gaps = 6/328 (1%)

Query: 10  FGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIA 69
           F +W  P  +     Q     +N+++    +DRLL GYD RLRP  G     V  NI + 
Sbjct: 17  FLVWD-PARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVT 75

Query: 70  SIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLN-LTLDNRVADQLWVPDTYFLNDKKS 128
           S   VS+ +M+YT+ ++F+Q W+D+RL +   P+N L L+N +A ++W PDT+F N KKS
Sbjct: 76  SFGPVSDTDMEYTIDVFFRQKWKDERLKFKG-PMNILRLNNLMASKIWTPDTFFHNGKKS 134

Query: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
             H +T+ N+++R+  DGT+LY +R+T  A C M L  +P+D  +C L+  SY YTT ++
Sbjct: 135 VAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEV 194

Query: 189 EFYW--RGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFI 246
            + W     D+         L Q+ ++   +  + +  STG Y  ++  F LKR IGYF+
Sbjct: 195 TYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFV 254

Query: 247 LQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAID 306
           +QTY+P I+  ILS VSFW+N ++  AR   G+TTVLTMTT++   R +LPK+ Y  A+D
Sbjct: 255 IQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMD 314

Query: 307 MYLMGCFVFVFMALLEYALVNYIFFGRG 334
            ++  C+ FVF AL+E+A VNY F  RG
Sbjct: 315 WFIAVCYAFVFSALIEFATVNY-FTKRG 341



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 18/29 (62%), Positives = 22/29 (75%)

Query: 484 VNAIDRWSRIFFPVVFSFFNIVYWLYYVN 512
           V+ IDR SRI FPV+F  FN+VYW  Y+N
Sbjct: 414 VSKIDRMSRIVFPVLFGTFNLVYWATYLN 442


>gi|189083762 gamma-aminobutyric acid A receptor, gamma 2 isoform 3
           precursor [Homo sapiens]
          Length = 515

 Score =  260 bits (665), Expect = 2e-69
 Identities = 133/345 (38%), Positives = 196/345 (56%), Gaps = 40/345 (11%)

Query: 40  VDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYN 99
           ++ LL+GYD +LRPD G  P  +  ++ + SI  V+ +NM+YT+ ++F Q W D+RL +N
Sbjct: 70  LNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFN 129

Query: 100 VIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA 159
                L L++ +  ++W+PDT+F N KK+  H +T  NRM+R+  DG VLY LR+T  A 
Sbjct: 130 STIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAE 189

Query: 160 CMMDLRRYPLDEQNCTLEIESY-------------------------------------- 181
           C + L  +P+DE +C LE  S+                                      
Sbjct: 190 CQLQLHNFPMDEHSCPLEFSSWSRSIAQAGMCSGVISAHYSLRFWGSTDPPTLASRVAGI 249

Query: 182 --GYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLK 239
             GY  ++I + W+     V       L QFS V  +  T+ V  ++G Y  +S+ F L 
Sbjct: 250 SDGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVYFDLS 309

Query: 240 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI 299
           R +GYF +QTY+P  LI +LSWVSFWIN DA  AR +LGITTVLTMTT++T  R++LPK+
Sbjct: 310 RRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKV 369

Query: 300 PYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEK 344
            YV A+D+++  CF+FVF AL+EY  ++Y    R P + K   +K
Sbjct: 370 SYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKK 414



 Score = 37.4 bits (85), Expect = 0.033
 Identities = 13/25 (52%), Positives = 19/25 (76%)

Query: 487 IDRWSRIFFPVVFSFFNIVYWLYYV 511
           +D ++RIFFP  F  FN+VYW+ Y+
Sbjct: 489 MDSYARIFFPTAFCLFNLVYWVSYL 513


>gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1
           precursor [Homo sapiens]
          Length = 456

 Score =  259 bits (663), Expect = 3e-69
 Identities = 135/357 (37%), Positives = 209/357 (58%), Gaps = 19/357 (5%)

Query: 12  IWSFPLIIAAVCAQSVNDPS-------NMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGM 64
           +W++ L+++ +  +S   PS       N ++    +DRLL GYD RLRP  G     V  
Sbjct: 11  LWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKT 70

Query: 65  NIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLN 124
           +I + S   VS+ +M+YT+ ++F+Q+W+D+RL +      L L+N +A ++W PDT+F N
Sbjct: 71  DIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHN 130

Query: 125 DKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYT 184
            KKS  H +T+ N+++R+  DGT+LY +R+T  A C M L  +P+D   C L+  SY YT
Sbjct: 131 GKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYT 190

Query: 185 TDDIEFYWRGDD--NAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNI 242
             ++ + W  +   + V       L Q+ ++   + +  V  STG Y  ++  F LKR I
Sbjct: 191 RAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKI 250

Query: 243 GYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYV 302
           GYF++QTY+P I+  ILS VSFW+N ++  AR   G+TTVLTMTT++   R +LPK+ Y 
Sbjct: 251 GYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYA 310

Query: 303 KAIDMYLMGCFVFVFMALLEYALVNYIFFGRG---------PQRQKKAAEKAASANN 350
            A+D ++  C+ FVF AL+E+A VNY F  RG         P++ KK  +     NN
Sbjct: 311 TAMDWFIAVCYAFVFSALIEFATVNY-FTKRGYAWDGKSVVPEKPKKVKDPLIKKNN 366



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 17/29 (58%), Positives = 22/29 (75%)

Query: 484 VNAIDRWSRIFFPVVFSFFNIVYWLYYVN 512
           V+ IDR SRI FP++F  FN+VYW  Y+N
Sbjct: 416 VSKIDRLSRIAFPLLFGIFNLVYWATYLN 444


>gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1
           precursor [Homo sapiens]
          Length = 456

 Score =  259 bits (663), Expect = 3e-69
 Identities = 135/357 (37%), Positives = 209/357 (58%), Gaps = 19/357 (5%)

Query: 12  IWSFPLIIAAVCAQSVNDPS-------NMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGM 64
           +W++ L+++ +  +S   PS       N ++    +DRLL GYD RLRP  G     V  
Sbjct: 11  LWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKT 70

Query: 65  NIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLN 124
           +I + S   VS+ +M+YT+ ++F+Q+W+D+RL +      L L+N +A ++W PDT+F N
Sbjct: 71  DIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHN 130

Query: 125 DKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYT 184
            KKS  H +T+ N+++R+  DGT+LY +R+T  A C M L  +P+D   C L+  SY YT
Sbjct: 131 GKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYT 190

Query: 185 TDDIEFYWRGDD--NAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNI 242
             ++ + W  +   + V       L Q+ ++   + +  V  STG Y  ++  F LKR I
Sbjct: 191 RAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKI 250

Query: 243 GYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYV 302
           GYF++QTY+P I+  ILS VSFW+N ++  AR   G+TTVLTMTT++   R +LPK+ Y 
Sbjct: 251 GYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYA 310

Query: 303 KAIDMYLMGCFVFVFMALLEYALVNYIFFGRG---------PQRQKKAAEKAASANN 350
            A+D ++  C+ FVF AL+E+A VNY F  RG         P++ KK  +     NN
Sbjct: 311 TAMDWFIAVCYAFVFSALIEFATVNY-FTKRGYAWDGKSVVPEKPKKVKDPLIKKNN 366



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 17/29 (58%), Positives = 22/29 (75%)

Query: 484 VNAIDRWSRIFFPVVFSFFNIVYWLYYVN 512
           V+ IDR SRI FP++F  FN+VYW  Y+N
Sbjct: 416 VSKIDRLSRIAFPLLFGIFNLVYWATYLN 444


>gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1
           precursor [Homo sapiens]
          Length = 456

 Score =  259 bits (663), Expect = 3e-69
 Identities = 135/357 (37%), Positives = 209/357 (58%), Gaps = 19/357 (5%)

Query: 12  IWSFPLIIAAVCAQSVNDPS-------NMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGM 64
           +W++ L+++ +  +S   PS       N ++    +DRLL GYD RLRP  G     V  
Sbjct: 11  LWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKT 70

Query: 65  NIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLN 124
           +I + S   VS+ +M+YT+ ++F+Q+W+D+RL +      L L+N +A ++W PDT+F N
Sbjct: 71  DIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHN 130

Query: 125 DKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYT 184
            KKS  H +T+ N+++R+  DGT+LY +R+T  A C M L  +P+D   C L+  SY YT
Sbjct: 131 GKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYT 190

Query: 185 TDDIEFYWRGDD--NAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNI 242
             ++ + W  +   + V       L Q+ ++   + +  V  STG Y  ++  F LKR I
Sbjct: 191 RAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKI 250

Query: 243 GYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYV 302
           GYF++QTY+P I+  ILS VSFW+N ++  AR   G+TTVLTMTT++   R +LPK+ Y 
Sbjct: 251 GYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYA 310

Query: 303 KAIDMYLMGCFVFVFMALLEYALVNYIFFGRG---------PQRQKKAAEKAASANN 350
            A+D ++  C+ FVF AL+E+A VNY F  RG         P++ KK  +     NN
Sbjct: 311 TAMDWFIAVCYAFVFSALIEFATVNY-FTKRGYAWDGKSVVPEKPKKVKDPLIKKNN 366



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 17/29 (58%), Positives = 22/29 (75%)

Query: 484 VNAIDRWSRIFFPVVFSFFNIVYWLYYVN 512
           V+ IDR SRI FP++F  FN+VYW  Y+N
Sbjct: 416 VSKIDRLSRIAFPLLFGIFNLVYWATYLN 444


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.138    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,496,582
Number of Sequences: 37866
Number of extensions: 686155
Number of successful extensions: 2106
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 63
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1925
Number of HSP's gapped (non-prelim): 112
length of query: 512
length of database: 18,247,518
effective HSP length: 107
effective length of query: 405
effective length of database: 14,195,856
effective search space: 5749321680
effective search space used: 5749321680
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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