BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1 precursor [Homo sapiens] (456 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 929 0.0 gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 929 0.0 gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 929 0.0 gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 929 0.0 gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 929 0.0 gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 929 0.0 gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1 p... 929 0.0 gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo s... 689 0.0 gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precurs... 689 0.0 gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5 pr... 642 0.0 gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor... 639 0.0 gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precurs... 503 e-142 gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precurso... 487 e-137 gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform ... 378 e-105 gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform ... 373 e-103 gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precurso... 367 e-101 gi|189083762 gamma-aminobutyric acid A receptor, gamma 2 isoform... 357 2e-98 gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3 ... 346 2e-95 gi|52426761 gamma-aminobutyric acid (GABA) A receptor, epsilon p... 298 9e-81 gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens] 275 5e-74 gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens] 275 5e-74 gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens] 275 5e-74 gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens] 275 6e-74 gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2 iso... 275 8e-74 gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo... 271 1e-72 gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo... 269 3e-72 gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens] 268 8e-72 gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1 p... 267 1e-71 gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3 is... 265 6e-71 gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3 iso... 265 6e-71 >gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1 precursor [Homo sapiens] Length = 456 Score = 929 bits (2402), Expect = 0.0 Identities = 456/456 (100%), Positives = 456/456 (100%) Query: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG Sbjct: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60 Query: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK Sbjct: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120 Query: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC Sbjct: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180 Query: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM Sbjct: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240 Query: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA Sbjct: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300 Query: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP Sbjct: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360 Query: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID Sbjct: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420 Query: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ Sbjct: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456 >gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1 precursor [Homo sapiens] Length = 456 Score = 929 bits (2402), Expect = 0.0 Identities = 456/456 (100%), Positives = 456/456 (100%) Query: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG Sbjct: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60 Query: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK Sbjct: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120 Query: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC Sbjct: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180 Query: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM Sbjct: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240 Query: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA Sbjct: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300 Query: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP Sbjct: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360 Query: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID Sbjct: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420 Query: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ Sbjct: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456 >gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1 precursor [Homo sapiens] Length = 456 Score = 929 bits (2402), Expect = 0.0 Identities = 456/456 (100%), Positives = 456/456 (100%) Query: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG Sbjct: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60 Query: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK Sbjct: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120 Query: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC Sbjct: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180 Query: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM Sbjct: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240 Query: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA Sbjct: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300 Query: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP Sbjct: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360 Query: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID Sbjct: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420 Query: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ Sbjct: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456 >gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1 precursor [Homo sapiens] Length = 456 Score = 929 bits (2402), Expect = 0.0 Identities = 456/456 (100%), Positives = 456/456 (100%) Query: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG Sbjct: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60 Query: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK Sbjct: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120 Query: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC Sbjct: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180 Query: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM Sbjct: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240 Query: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA Sbjct: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300 Query: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP Sbjct: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360 Query: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID Sbjct: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420 Query: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ Sbjct: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456 >gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1 precursor [Homo sapiens] Length = 456 Score = 929 bits (2402), Expect = 0.0 Identities = 456/456 (100%), Positives = 456/456 (100%) Query: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG Sbjct: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60 Query: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK Sbjct: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120 Query: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC Sbjct: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180 Query: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM Sbjct: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240 Query: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA Sbjct: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300 Query: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP Sbjct: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360 Query: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID Sbjct: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420 Query: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ Sbjct: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456 >gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1 precursor [Homo sapiens] Length = 456 Score = 929 bits (2402), Expect = 0.0 Identities = 456/456 (100%), Positives = 456/456 (100%) Query: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG Sbjct: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60 Query: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK Sbjct: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120 Query: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC Sbjct: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180 Query: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM Sbjct: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240 Query: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA Sbjct: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300 Query: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP Sbjct: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360 Query: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID Sbjct: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420 Query: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ Sbjct: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456 >gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1 precursor [Homo sapiens] Length = 456 Score = 929 bits (2402), Expect = 0.0 Identities = 456/456 (100%), Positives = 456/456 (100%) Query: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG Sbjct: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60 Query: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK Sbjct: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120 Query: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC Sbjct: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180 Query: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM Sbjct: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240 Query: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA Sbjct: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300 Query: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP Sbjct: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360 Query: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID Sbjct: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420 Query: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ Sbjct: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456 >gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo sapiens] Length = 451 Score = 689 bits (1777), Expect = 0.0 Identities = 340/418 (81%), Positives = 369/418 (88%), Gaps = 2/418 (0%) Query: 32 QDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDV 91 +DE K+N T+FTRILDRLLDGYDNRLRPGLG+ +TEV T+I+VTSFGPVSD DMEYTIDV Sbjct: 32 EDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDV 91 Query: 92 FFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITED 151 FFRQ WKDERLKFKGPM +LRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI +D Sbjct: 92 FFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDD 151 Query: 152 GTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAED 211 GTLLYTMRLTV+AECPMHLEDFPMDAH+CPLKFGSYAYT +EV Y WT + SV VA D Sbjct: 152 GTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPD 211 Query: 212 GSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271 GSRLNQYDLLGQ++ ++SSTGEY VMT HFHLKRKIGYFVIQTYLPCIMTVILSQVS Sbjct: 212 GSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271 Query: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF Sbjct: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331 Query: 332 ATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAK 391 ATVNYFTKRG+AWDGKSVV +K KK K ++ +NN YA +Y PNL++ DP L+TI+K Sbjct: 332 ATVNYFTKRGWAWDGKSVVNDK-KKEKASVMIQNNAYAVAVANYAPNLSK-DPVLSTISK 389 Query: 392 SATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQL 449 SAT KPE KP E KKTFNSVSKIDR+SRI FP+LFG FNLVYWATYLNREP L Sbjct: 390 SATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREPVL 447 >gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precursor [Homo sapiens] Length = 451 Score = 689 bits (1777), Expect = 0.0 Identities = 340/418 (81%), Positives = 369/418 (88%), Gaps = 2/418 (0%) Query: 32 QDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDV 91 +DE K+N T+FTRILDRLLDGYDNRLRPGLG+ +TEV T+I+VTSFGPVSD DMEYTIDV Sbjct: 32 EDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDV 91 Query: 92 FFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITED 151 FFRQ WKDERLKFKGPM +LRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI +D Sbjct: 92 FFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDD 151 Query: 152 GTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAED 211 GTLLYTMRLTV+AECPMHLEDFPMDAH+CPLKFGSYAYT +EV Y WT + SV VA D Sbjct: 152 GTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPD 211 Query: 212 GSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271 GSRLNQYDLLGQ++ ++SSTGEY VMT HFHLKRKIGYFVIQTYLPCIMTVILSQVS Sbjct: 212 GSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271 Query: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF Sbjct: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331 Query: 332 ATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAK 391 ATVNYFTKRG+AWDGKSVV +K KK K ++ +NN YA +Y PNL++ DP L+TI+K Sbjct: 332 ATVNYFTKRGWAWDGKSVVNDK-KKEKASVMIQNNAYAVAVANYAPNLSK-DPVLSTISK 389 Query: 392 SATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQL 449 SAT KPE KP E KKTFNSVSKIDR+SRI FP+LFG FNLVYWATYLNREP L Sbjct: 390 SATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREPVL 447 >gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5 precursor [Homo sapiens] Length = 462 Score = 642 bits (1656), Expect = 0.0 Identities = 319/424 (75%), Positives = 358/424 (84%), Gaps = 7/424 (1%) Query: 30 SLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTI 89 S++DE DN T+FTRILD LLDGYDNRLRPGLGER+T+V+TDI+VTSFGPVSD +MEYTI Sbjct: 37 SVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTI 96 Query: 90 DVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIT 149 DVFFRQSWKDERL+FKGPM L LNNL+ASKIWTPDTFFHNGKKS+AHNMT PNKLLR+ Sbjct: 97 DVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLE 156 Query: 150 EDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVA 209 +DGTLLYTMRLT+ AECPM LEDFPMDAHACPLKFGSYAY +EVVY WT +SVVVA Sbjct: 157 DDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVA 216 Query: 210 EDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQ 269 EDGSRLNQY L+GQTV + + +STGEY +MT HFHLKRKIGYFVIQTYLPCIMTVILSQ Sbjct: 217 EDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQ 276 Query: 270 VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI 329 VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI Sbjct: 277 VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI 336 Query: 330 EFATVNYFTKRGYAWDGKSVV-PEKPKKVKDPLIKKN-NTYAPTATSYTPNLARGDPGLA 387 EFATVNYFTKRG+AWDGK + K KK ++ ++ K+ N + S+ PN+ P Sbjct: 337 EFATVNYFTKRGWAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNI----PKEQ 392 Query: 388 TIAKSATIEPKEVKP-ETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNRE 446 T A ++ VKP E K E KKT+NS+SKID++SRI FP+LFG FNLVYWATYLNRE Sbjct: 393 TPAGTSNTTSVSVKPSEEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNRE 452 Query: 447 PQLK 450 P +K Sbjct: 453 PVIK 456 >gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor [Homo sapiens] Length = 492 Score = 639 bits (1648), Expect = 0.0 Identities = 324/436 (74%), Positives = 357/436 (81%), Gaps = 17/436 (3%) Query: 29 PSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYT 88 P + D+ DN T+FTRILDRLLDGYDNRLRPGLG+ VTEVKTDI+VTSFGPVSD DMEYT Sbjct: 54 PDIPDDSTDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYT 113 Query: 89 IDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI 148 IDVFFRQ+W DERLKF GPM +L LNNL+ASKIWTPDTFFHNGKKSVAHNMT PNKLLR+ Sbjct: 114 IDVFFRQTWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRL 173 Query: 149 TEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVV 208 ++GTLLYTMRLT+ AECPMHLEDFPMD HACPLKFGSYAYT AEVVY WT +SV V Sbjct: 174 VDNGTLLYTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEV 233 Query: 209 AEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS 268 A+DGSRLNQYDLLG V + I++SSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS Sbjct: 234 AQDGSRLNQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS 293 Query: 269 QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL 328 QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL Sbjct: 294 QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL 353 Query: 329 IEFATVNYFTKRGYAWDGKSVVPE----KPKKVKDPLIKKNNTYAPTATSYTPNLARGDP 384 IEFATVNYFTKR +AW+GK VPE K K P K + T+ T+Y NLA+ D Sbjct: 354 IEFATVNYFTKRSWAWEGKK-VPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAK-DT 411 Query: 385 GLATIAKSAT----------IEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIF 434 +TI+K A PK + P E KT+NSVSK+D++SRI FP+LF IF Sbjct: 412 EFSTISKGAAPSASSTPTIIASPKATYVQDSPTE-TKTYNSVSKVDKISRIIFPVLFAIF 470 Query: 435 NLVYWATYLNREPQLK 450 NLVYWATY+NRE +K Sbjct: 471 NLVYWATYVNRESAIK 486 >gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precursor [Homo sapiens] Length = 453 Score = 503 bits (1295), Expect = e-142 Identities = 258/418 (61%), Positives = 307/418 (73%), Gaps = 20/418 (4%) Query: 43 TRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102 +RILD LL+GYDNRLRPG G VTEVKTDI+VTSFGPVSD +MEYT+DVFFRQ+W DERL Sbjct: 33 SRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERL 92 Query: 103 KFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTV 162 KF GP +L LNNLM SKIWTPDTFF NGKKS+AHNMT PNKL RI ++GT+LYTMRLT+ Sbjct: 93 KFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTI 152 Query: 163 RAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLG 222 A+CPM L +FPMD HACPLKFGSYAY ++E++Y W + P SV V E+ S L QYDL+G Sbjct: 153 NADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIG 212 Query: 223 QTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 282 QTV S ++S+TGEYV+MT +FHL+RK+GYF+IQ Y PCIMTVILSQVSFW+N+ESVPAR Sbjct: 213 QTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPAR 272 Query: 283 TVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT---- 338 TVFG+TTVLTMTTLSISAR+SLPKV+YATAMDWFIAVC+AFVFSALIEFA VNYFT Sbjct: 273 TVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQT 332 Query: 339 -----KRGYAWD-----GKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLAT 388 K +A K+ P + + V P K + T+ S P ++ + Sbjct: 333 QKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLS-LPIVSSSEAN--- 388 Query: 389 IAKSATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNRE 446 K T P PP F SKID+ SRI FP+ F FNLVYW YL+++ Sbjct: 389 --KVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVYLSKD 444 >gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precursor [Homo sapiens] Length = 554 Score = 487 bits (1253), Expect = e-137 Identities = 237/335 (70%), Positives = 281/335 (83%), Gaps = 3/335 (0%) Query: 4 SPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGE 63 S G+S L + L L+ S GQ +++L T FTRILD LLDGYDNRLRPG G Sbjct: 13 SAGVSFALLRF-LCLAVCLNESPGQNQKEEKLC--TENFTRILDSLLDGYDNRLRPGFGG 69 Query: 64 RVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWT 123 VTEVKTDI+VTSFGPVSD +MEYT+DVFFRQ+W D+RLK+ GP+ +LRLNN+M +K+WT Sbjct: 70 PVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKYDGPIEILRLNNMMVTKVWT 129 Query: 124 PDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLK 183 PDTFF NGKKSV+HNMT PNKL RI +GT+LYTMRLT+ AECPM L DFPMD HACPLK Sbjct: 130 PDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLK 189 Query: 184 FGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTH 243 FGSYAY ++E++Y WT+ P +SV V ++ S L QYDL+GQTV S ++S TGEY+VMT + Sbjct: 190 FGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLIGQTVSSETIKSITGEYIVMTVY 249 Query: 244 FHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNS 303 FHL+RK+GYF+IQTY+PCIMTVILSQVSFW+N+ESVPARTVFG+TTVLTMTTLSISAR+S Sbjct: 250 FHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHS 309 Query: 304 LPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT 338 LPKV+YATAMDWFIAVC+AFVFSALIEFA VNYFT Sbjct: 310 LPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFT 344 Score = 49.7 bits (117), Expect = 6e-06 Identities = 22/49 (44%), Positives = 32/49 (65%), Gaps = 1/49 (2%) Query: 404 TKPPE-PKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQLKA 451 T PP P + + SKID+ +RI FP+ FG FN+VYW YL+++ K+ Sbjct: 502 TPPPSAPPPSGSGTSKIDKYARILFPVTFGAFNMVYWVVYLSKDTMEKS 550 >gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform 1 precursor [Homo sapiens] Length = 475 Score = 378 bits (970), Expect = e-105 Identities = 209/468 (44%), Positives = 288/468 (61%), Gaps = 38/468 (8%) Query: 4 SPGLSDCLWAWILLLSTLTGRSYGQPS---LQDELKDNTTVFTR---------ILDRLLD 51 +P S + WILLL +L Q S +D + T V T IL+ LL+ Sbjct: 16 TPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLE 75 Query: 52 GYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVL 111 GYDN+LRP +G + T + TD++V S GPV+ +MEYTID+FF Q+W D RLKF + VL Sbjct: 76 GYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVL 135 Query: 112 RLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLE 171 RLN+ M KIW PDTFF N KK+ AH +T PN++LRI DG +LYT+RLT+ AEC + L Sbjct: 136 RLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLH 195 Query: 172 DFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-RLNQYDLLGQTVDSGIV 230 +FPMD H+CPL+F SY Y R E+VY+W R SV V + S RL Q+ +G + +V Sbjct: 196 NFPMDEHSCPLEFSSYGYPREEIVYQWKRS---SVEVGDTRSWRLYQFSFVGLRNTTEVV 252 Query: 231 QSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTV 290 ++++G+YVVM+ +F L R++GYF IQTY+PC + V+LS VSFW+N+++VPART G+TTV Sbjct: 253 KTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTV 312 Query: 291 LTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVV 350 LTMTTLS AR SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF + Sbjct: 313 LTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFV------SNRKPS 366 Query: 351 PEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKS-------ATIEPKEVKP- 402 +K KK K+PL++ + APT P A AT + ++ K+ Sbjct: 367 KDKDKKKKNPLLRMFSFKAPT-IDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASF 425 Query: 403 -------ETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYL 443 T + ++K+D +RI FP F +FNLVYW +YL Sbjct: 426 FCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYL 473 >gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform 2 precursor [Homo sapiens] Length = 467 Score = 373 bits (958), Expect = e-103 Identities = 211/468 (45%), Positives = 284/468 (60%), Gaps = 46/468 (9%) Query: 4 SPGLSDCLWAWILLLSTLTGRSYGQPS---LQDELKDNTTVFTR---------ILDRLLD 51 +P S + WILLL +L Q S +D + T V T IL+ LL+ Sbjct: 16 TPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLE 75 Query: 52 GYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVL 111 GYDN+LRP +G + T + TD++V S GPV+ +MEYTID+FF Q+W D RLKF + VL Sbjct: 76 GYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVL 135 Query: 112 RLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLE 171 RLN+ M KIW PDTFF N KK+ AH +T PN++LRI DG +LYT+RLT+ AEC + L Sbjct: 136 RLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLH 195 Query: 172 DFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-RLNQYDLLGQTVDSGIV 230 +FPMD H+CPL+F SY Y R E+VY+W R SV V + S RL Q+ +G + +V Sbjct: 196 NFPMDEHSCPLEFSSYGYPREEIVYQWKRS---SVEVGDTRSWRLYQFSFVGLRNTTEVV 252 Query: 231 QSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTV 290 ++++G+YVVM+ +F L R++GYF IQTY+PC + V+LS VSFW+N+++VPART G+TTV Sbjct: 253 KTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTV 312 Query: 291 LTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVV 350 LTMTTLS AR SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF V Sbjct: 313 LTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYF-----------VS 361 Query: 351 PEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKS-------ATIEPKEVKP- 402 KP K KD KK APT P A AT + ++ K+ Sbjct: 362 NRKPSKDKD---KKKKNPAPT-IDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASF 417 Query: 403 -------ETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYL 443 T + ++K+D +RI FP F +FNLVYW +YL Sbjct: 418 FCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYL 465 >gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precursor [Homo sapiens] Length = 465 Score = 367 bits (942), Expect = e-101 Identities = 195/412 (47%), Positives = 256/412 (62%), Gaps = 24/412 (5%) Query: 43 TRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102 T+IL+ LL GYDN+LRP +G R T ++TD++V S GPV +MEYTID+ F Q+W D RL Sbjct: 65 TQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRL 124 Query: 103 KFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTV 162 KF M VL LN+ M KIW PDTFF N +KS AH +T PN+LLRI DG +LYT+RLT+ Sbjct: 125 KFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTI 184 Query: 163 RAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-RLNQYDLL 221 AEC + L +FPMD H+CPL+F SY Y + E+ Y+W + SV VA+ RL Q+ + Sbjct: 185 NAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKP---SVEVADPKYWRLYQFAFV 241 Query: 222 GQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 281 G + I + +G+YV+MT F L R++GYF IQTY+PCI+TV+LS VSFW+N+++VPA Sbjct: 242 GLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPA 301 Query: 282 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 341 RT G+TTVLTMTTLS AR SLPKV+Y TAMD F++VC+ FVF+AL+E+ T++YFT Sbjct: 302 RTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSN- 360 Query: 342 YAWDGKSVVPEKPKKVK----------DPLIKKNNTYAPTATSYTPNLARGDPGLATIAK 391 GK+ ++ K K LI NN P Y G + Sbjct: 361 --QKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGYQCLEGKDCASFFCC 418 Query: 392 SATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYL 443 T + ++KID SRI FP F +FNLVYW YL Sbjct: 419 FEDC-------RTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYL 463 >gi|189083762 gamma-aminobutyric acid A receptor, gamma 2 isoform 3 precursor [Homo sapiens] Length = 515 Score = 357 bits (915), Expect = 2e-98 Identities = 208/508 (40%), Positives = 289/508 (56%), Gaps = 78/508 (15%) Query: 4 SPGLSDCLWAWILLLSTLTGRSYGQPS---LQDELKDNTTVFTR---------ILDRLLD 51 +P S + WILLL +L Q S +D + T V T IL+ LL+ Sbjct: 16 TPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLE 75 Query: 52 GYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVL 111 GYDN+LRP +G + T + TD++V S GPV+ +MEYTID+FF Q+W D RLKF + VL Sbjct: 76 GYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVL 135 Query: 112 RLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLE 171 RLN+ M KIW PDTFF N KK+ AH +T PN++LRI DG +LYT+RLT+ AEC + L Sbjct: 136 RLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLH 195 Query: 172 DFPMDAHACPLKFGSYA----------------------------------------YTR 191 +FPMD H+CPL+F S++ Y R Sbjct: 196 NFPMDEHSCPLEFSSWSRSIAQAGMCSGVISAHYSLRFWGSTDPPTLASRVAGISDGYPR 255 Query: 192 AEVVYEWTREPARSVVVAEDGS-RLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKI 250 E+VY+W R SV V + S RL Q+ +G + +V++++G+YVVM+ +F L R++ Sbjct: 256 EEIVYQWKRS---SVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVYFDLSRRM 312 Query: 251 GYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYA 310 GYF IQTY+PC + V+LS VSFW+N+++VPART G+TTVLTMTTLS AR SLPKV+Y Sbjct: 313 GYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYV 372 Query: 311 TAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAP 370 TAMD F++VC+ FVFSAL+E+ T++YF + +K KK K+PL++ + AP Sbjct: 373 TAMDLFVSVCFIFVFSALVEYGTLHYFV------SNRKPSKDKDKKKKNPLLRMFSFKAP 426 Query: 371 TATSYTPNLARGDPGLATIAKS-------ATIEPKEVKP--------ETKPPEPKKTFNS 415 T P A AT + ++ K+ T + Sbjct: 427 T-IDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIR 485 Query: 416 VSKIDRLSRIAFPLLFGIFNLVYWATYL 443 ++K+D +RI FP F +FNLVYW +YL Sbjct: 486 IAKMDSYARIFFPTAFCLFNLVYWVSYL 513 >gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3 [Homo sapiens] Length = 467 Score = 346 bits (888), Expect = 2e-95 Identities = 191/436 (43%), Positives = 258/436 (59%), Gaps = 39/436 (8%) Query: 36 KDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQ 95 K T T IL++LL YD +LRP +G + T + DI+V S GPVS +MEY ID+FF Q Sbjct: 41 KSQDTDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQ 100 Query: 96 SWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLL 155 +W D RL+F M +L LN+ M IW PDT F N K + AH +T PN+LLRI DG +L Sbjct: 101 TWTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKIL 160 Query: 156 YTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-R 214 YT+RLT+ AEC + L +FPMD H+CPL F SY Y + E++Y W + SV A+ S R Sbjct: 161 YTLRLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRK---NSVEAADQKSWR 217 Query: 215 LNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWL 274 L Q+D +G + IV +S G+YVVMT +F L R++GYF IQTY+PCI+TV+LS VSFW+ Sbjct: 218 LYQFDFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWI 277 Query: 275 NRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATV 334 +++ PART G+TTVLTMTTLS AR SLP+V+Y TAMD F+ VC+ FVF+AL+E+AT+ Sbjct: 278 KKDATPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATL 337 Query: 335 NYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAP-----TATSYTPNLARGDPGLATI 389 NY++ P KK L ++ + P A S L P A I Sbjct: 338 NYYS--------SCRKPTTTKKTTSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMI 389 Query: 390 AKSATIEPKEVK--------------------PETKPPEPKK--TFNSVSKIDRLSRIAF 427 + ++ +E + E K +K + ++D SR+ F Sbjct: 390 TLNNSVYWQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRKGRIHIDILELDSYSRVFF 449 Query: 428 PLLFGIFNLVYWATYL 443 P F +FNLVYW YL Sbjct: 450 PTSFLLFNLVYWVGYL 465 >gi|52426761 gamma-aminobutyric acid (GABA) A receptor, epsilon precursor [Homo sapiens] Length = 506 Score = 298 bits (762), Expect = 9e-81 Identities = 164/446 (36%), Positives = 246/446 (55%), Gaps = 56/446 (12%) Query: 43 TRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102 +RIL+ +L YD++LRPG+GE+ T V +I V S GP+S DMEYTID+ F Q+W DERL Sbjct: 72 SRILNTILSNYDHKLRPGIGEKPTVVTVEISVNSLGPLSILDMEYTIDIIFSQTWYDERL 131 Query: 103 KFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTV 162 + L LN + S++W PDTFF N K++ H +TMPN+++RI +DG +LYT+R+T+ Sbjct: 132 CYNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTI 191 Query: 163 RAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLG 222 A C +H+ FPMD+H+CPL F S++Y E++Y+W E + + ++ +L Q+D G Sbjct: 192 DAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKW--ENFKLEINEKNSWKLFQFDFTG 249 Query: 223 QTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 282 + + I+ + G+++VMT F++ R+ GY Q Y+P +T +LS VSFW+ ES PAR Sbjct: 250 VSNKTEIITTPVGDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPAR 309 Query: 283 TVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGY 342 T G+T+VLTMTTL +R + P+V+Y TA+D++IA+C+ F F AL+EFA +N+ Sbjct: 310 TSLGITSVLTMTTLGTFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFLIY--- 366 Query: 343 AWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPK--EV 400 K++ P I N+ A T A + + T E E Sbjct: 367 ----NQTKAHASPKLRHPRI---NSRAHARTRARSRACARQHQEAFVCQIVTTEGSDGEE 419 Query: 401 KPE---TKPPEP----------------------KKTFNSVS-----------------K 418 +P +PP P KK F V + Sbjct: 420 RPSCSAQQPPSPGSPEGPRSLCSKLACCEWCKRFKKYFCMVPDCEGSTWQQGRLCIHVYR 479 Query: 419 IDRLSRIAFPLLFGIFNLVYWATYLN 444 +D SR+ FP+ F FN++YW LN Sbjct: 480 LDNYSRVVFPVTFFFFNVLYWLVCLN 505 >gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens] Length = 452 Score = 275 bits (704), Expect = 5e-74 Identities = 154/403 (38%), Positives = 234/403 (58%), Gaps = 15/403 (3%) Query: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102 LD+L+ GYD R+RP V +IF+ SFG V++ M+Y +++F RQ W D RL Sbjct: 48 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRL 107 Query: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161 + P L L+ M IW PD FF N K + H++T NKLLRI+++G +LY++RLT Sbjct: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167 Query: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221 + CPM L++FPMD C ++ S+ YT ++++EW + V VAE G L Q+ +L Sbjct: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGP--VQVAE-GLTLPQF-IL 223 Query: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279 + + G +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ Sbjct: 224 KEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 283 Query: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339 PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ ++ Sbjct: 284 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR 343 Query: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399 + + ++ K +D + ++ + + G T K+ P Sbjct: 344 QHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDG-----TAVKATPANPLP 398 Query: 400 VKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442 P+ KK + +ID +SR AFPL F IFN+ YW TY Sbjct: 399 QPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441 >gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens] Length = 449 Score = 275 bits (704), Expect = 5e-74 Identities = 161/404 (39%), Positives = 239/404 (59%), Gaps = 21/404 (5%) Query: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102 LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL Sbjct: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106 Query: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161 + P L L+ M IW PD FF N K + H +T NKLLRI ++G +LY++RLT Sbjct: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166 Query: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221 + CPM L++FPMD C ++ S+ YT ++++EW E V VAE G L Q+ LL Sbjct: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAP--VQVAE-GLTLPQF-LL 222 Query: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279 + D +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ Sbjct: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282 Query: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339 PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++ Sbjct: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 342 Query: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399 + + + + +K KD ++++ ++ TA P L D + P + Sbjct: 343 Q----HKELLRFRRKRKNKDDEVRESR-FSFTAYGMGPCLQAKD----GMTPKGPNHPVQ 393 Query: 400 VKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442 V P++ P E +K F + KID +SR FPL F IFN+ YW Y Sbjct: 394 VMPKS-PDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 436 >gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens] Length = 452 Score = 275 bits (704), Expect = 5e-74 Identities = 154/403 (38%), Positives = 234/403 (58%), Gaps = 15/403 (3%) Query: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102 LD+L+ GYD R+RP V +IF+ SFG V++ M+Y +++F RQ W D RL Sbjct: 48 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRL 107 Query: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161 + P L L+ M IW PD FF N K + H++T NKLLRI+++G +LY++RLT Sbjct: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167 Query: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221 + CPM L++FPMD C ++ S+ YT ++++EW + V VAE G L Q+ +L Sbjct: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGP--VQVAE-GLTLPQF-IL 223 Query: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279 + + G +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ Sbjct: 224 KEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 283 Query: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339 PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ ++ Sbjct: 284 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR 343 Query: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399 + + ++ K +D + ++ + + G T K+ P Sbjct: 344 QHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDG-----TAVKATPANPLP 398 Query: 400 VKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442 P+ KK + +ID +SR AFPL F IFN+ YW TY Sbjct: 399 QPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441 >gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens] Length = 452 Score = 275 bits (703), Expect = 6e-74 Identities = 153/403 (37%), Positives = 234/403 (58%), Gaps = 15/403 (3%) Query: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102 LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL Sbjct: 48 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107 Query: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161 + P L L+ M IW PD FF N K + H++T NKLLRI+++G +LY++RLT Sbjct: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167 Query: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221 + CPM L++FPMD C ++ S+ YT ++++EW + V VAE G L Q+ +L Sbjct: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGP--VQVAE-GLTLPQF-IL 223 Query: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279 + + G +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ Sbjct: 224 KEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 283 Query: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339 PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ ++ Sbjct: 284 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR 343 Query: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399 + + ++ K +D + ++ + + G T K+ P Sbjct: 344 QHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDG-----TAVKATPANPLP 398 Query: 400 VKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442 P+ KK + +ID +SR AFPL F IFN+ YW TY Sbjct: 399 QPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441 >gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2 isoform 2 [Homo sapiens] Length = 474 Score = 275 bits (702), Expect = 8e-74 Identities = 163/482 (33%), Positives = 250/482 (51%), Gaps = 67/482 (13%) Query: 11 LWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKT 70 +W++ L+++ + +S PS N ++ +DRLL GYD RLRP G V Sbjct: 12 IWSFPLIIAAVCAQSVNDPS-------NMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGM 64 Query: 71 DIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHN 130 +I + S VS+ +M+YT+ ++F+Q+W+D+RL + L L+N +A ++W PDT+F N Sbjct: 65 NIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLN 124 Query: 131 GKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYT 190 KKS H +T+ N+++R+ DGT+LY +R+T A C M L +P+D C L+ SY YT Sbjct: 125 DKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYT 184 Query: 191 RAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKI 250 ++ + W + + V L Q+ ++ + + V STG Y ++ F LKR I Sbjct: 185 TDDIEFYWRGDD--NAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNI 242 Query: 251 GYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYA 310 GYF++QTY+P I+ ILS VSFW+N ++ AR G+TTVLTMTT++ R +LPK+ Y Sbjct: 243 GYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYV 302 Query: 311 TAMDWFIAVCYAFVFSALIEFATVNY-FTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYA 369 A+D ++ C+ FVF AL+E+A VNY F RG P++ KK + NN Sbjct: 303 KAIDMYLMGCFVFVFMALLEYALVNYIFFGRG---------PQRQKKAAEKAASANNEKM 353 Query: 370 ----------------------PTATSYTPNLARGDPGLATIAKSAT------------- 394 ATS + GDP +A A+ Sbjct: 354 RLDVNKMDPHENILLSTLEIKNEMATSEAV-MGLGDPRSTMLAYDASSIQYRKAGLPRHS 412 Query: 395 ---------IEPKEVKPETKPPEPKKT---FNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442 + K+ + + + K T V+ IDR SRI FP++F FN+VYW Y Sbjct: 413 FGRNALERHVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYY 472 Query: 443 LN 444 +N Sbjct: 473 VN 474 >gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo sapiens] Length = 457 Score = 271 bits (692), Expect = 1e-72 Identities = 156/415 (37%), Positives = 235/415 (56%), Gaps = 28/415 (6%) Query: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102 LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL Sbjct: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101 Query: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161 + P L L+ M IW PD FF N K + H +T NKLLRI+ +G +LY++R+T Sbjct: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161 Query: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221 + CPM L++FPMD C ++ S+ YT ++++EW + A V DG L Q+ +L Sbjct: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVA---DGLTLPQF-IL 217 Query: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279 + D +TG++ + FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++ Sbjct: 218 KEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAA 277 Query: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339 PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++ Sbjct: 278 PARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 337 Query: 340 RGYAWDGKSVV--PEKPKKVKDPLIK-------KNNTYAPTATSYTPNLARGDPGLAT-- 388 + K ++ K + K P++ + +A P + G++ Sbjct: 338 Q-----HKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQAKDGISVKG 392 Query: 389 IAKSATIEPKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442 S T P P P E +K F KID++SRI FP+ F IFN+ YW Y Sbjct: 393 ANNSNTTNPPPA-PSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 446 >gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo sapiens] Length = 449 Score = 269 bits (688), Expect = 3e-72 Identities = 154/407 (37%), Positives = 233/407 (57%), Gaps = 20/407 (4%) Query: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102 LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL Sbjct: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101 Query: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161 + P L L+ M IW PD FF N K + H +T NKLLRI+ +G +LY++R+T Sbjct: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161 Query: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221 + CPM L++FPMD C ++ S+ YT ++++EW + A V DG L Q+ +L Sbjct: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVA---DGLTLPQF-IL 217 Query: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279 + D +TG++ + FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++ Sbjct: 218 KEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAA 277 Query: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339 PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++ Sbjct: 278 PARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 337 Query: 340 RGYAWDGKSVVPEKPKKVKDPLIKK-NNTYAPTATSYTPNLARGDPGLAT--IAKSATIE 396 + K ++ + K+ + + +A P + G++ S T Sbjct: 338 Q-----HKELLRFRRKRRHHKEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTN 392 Query: 397 PKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442 P P P E +K F KID++SRI FP+ F IFN+ YW Y Sbjct: 393 PPPA-PSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 438 >gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens] Length = 464 Score = 268 bits (685), Expect = 8e-72 Identities = 162/414 (39%), Positives = 237/414 (57%), Gaps = 26/414 (6%) Query: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102 LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL Sbjct: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106 Query: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161 + P L L+ M IW PD FF N K + H +T NKLLRI ++G +LY++RLT Sbjct: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166 Query: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221 + CPM L++FPMD C ++ S+ YT ++++EW E V VAE G L Q+ LL Sbjct: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAP--VQVAE-GLTLPQF-LL 222 Query: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279 + D +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ Sbjct: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282 Query: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT- 338 PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ + Sbjct: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 342 Query: 339 --------KRGYAWDGKSVVPEKPKKVKDPLIK-KNNTYAPTATSYTPNLARGDPGLATI 389 +R ++ EK + D + + + ++ TA P L D + Sbjct: 343 QHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKD----GM 398 Query: 390 AKSATIEPKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442 P +V P++ P E +K F + KID +SR FPL F IFN+ YW Y Sbjct: 399 TPKGPNHPVQVMPKS-PDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451 >gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1 precursor [Homo sapiens] Length = 474 Score = 267 bits (683), Expect = 1e-71 Identities = 165/472 (34%), Positives = 248/472 (52%), Gaps = 56/472 (11%) Query: 15 ILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFV 74 +++ S +PS +K+ +DRLL GYD RLRP G +V I V Sbjct: 17 VMITMVCCAHSTNEPSNMSYVKET-------VDRLLKGYDIRLRPDFGGPPVDVGMRIDV 69 Query: 75 TSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKS 134 S VS+ +M+YT+ ++F+QSWKD+RL + G L L+N +A ++W PDT+F N KKS Sbjct: 70 ASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKS 129 Query: 135 VAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEV 194 H +T+ N+++R+ DGT+LY +R+T A C M L +P+D C L+ SY YT ++ Sbjct: 130 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 189 Query: 195 VYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFV 254 + W V + L Q+ ++ + S V+ +TG Y ++ F LKR IGYF+ Sbjct: 190 EFYW--NGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFI 247 Query: 255 IQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMD 314 +QTY+P + ILS VSFW+N ++ AR G+TTVLTMTT+S R +LPK+ Y A+D Sbjct: 248 LQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAID 307 Query: 315 WFIAVCYAFVFSALIEFATVNYF------TKRGYAWDGKSVVPEKPK----KVK------ 358 ++ C+ FVF AL+E+A VNY K+G + +S EK K KV+ Sbjct: 308 IYLMGCFVFVFLALLEYAFVNYIFFGKGPQKKGASKQDQS-ANEKNKLEMNKVQVDAHGN 366 Query: 359 ---DPLIKKNNTYA---------PTATSYT----------PNLARGDPGLAT----IAKS 392 L +N T P AT Y+ P +R G A + Sbjct: 367 ILLSTLEIRNETSGSEVLTSVSDPKATMYSYDSASIQYRKPLSSREAYGRALDRHGVPSK 426 Query: 393 ATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLN 444 I + + + K P+ V+ ID+ SR+ FP+ F +FN+VYW Y++ Sbjct: 427 GRIRRRASQLKVKIPD----LTDVNSIDKWSRMFFPITFSLFNVVYWLYYVH 474 >gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3 isoform 2 precursor [Homo sapiens] Length = 473 Score = 265 bits (677), Expect = 6e-71 Identities = 158/445 (35%), Positives = 232/445 (52%), Gaps = 42/445 (9%) Query: 38 NTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSW 97 N + +D+LL GYD RLRP G V +I + S VS+ +M+YT+ ++F+Q W Sbjct: 33 NMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYW 92 Query: 98 KDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYT 157 +D+RL + G L L+N +A ++W PDT+F N KKS H +T+ N+++R+ DGT+LY Sbjct: 93 RDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYG 152 Query: 158 MRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQ 217 +R+T A C M L +P+D C L+ SY YT ++ + W V + L Q Sbjct: 153 LRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYW--RGGDKAVTGVERIELPQ 210 Query: 218 YDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 277 + ++ + S V +TG Y ++ F LKR IGYF++QTY+P I+ ILS VSFW+N + Sbjct: 211 FSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYD 270 Query: 278 SVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNY- 336 + AR G+TTVLTMTT++ R +LPK+ Y A+D ++ C+ FVF AL+E+A VNY Sbjct: 271 ASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYI 330 Query: 337 FTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAP-------TATSYTPNLARGDPGLATI 389 F RG K + EK K K+ K + T+ + G+ Sbjct: 331 FFGRGPQRQKK--LAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDT 388 Query: 390 AKSATIEPK---EVKPETKPPE------------PKKT---------------FNSVSKI 419 SA + + ++ P E KKT V+ I Sbjct: 389 RNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAI 448 Query: 420 DRLSRIAFPLLFGIFNLVYWATYLN 444 DR SRI FP F +FNLVYW Y+N Sbjct: 449 DRWSRIVFPFTFSLFNLVYWLYYVN 473 >gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3 isoform 1 precursor [Homo sapiens] Length = 473 Score = 265 bits (677), Expect = 6e-71 Identities = 158/445 (35%), Positives = 232/445 (52%), Gaps = 42/445 (9%) Query: 38 NTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSW 97 N + +D+LL GYD RLRP G V +I + S VS+ +M+YT+ ++F+Q W Sbjct: 33 NMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYW 92 Query: 98 KDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYT 157 +D+RL + G L L+N +A ++W PDT+F N KKS H +T+ N+++R+ DGT+LY Sbjct: 93 RDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYG 152 Query: 158 MRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQ 217 +R+T A C M L +P+D C L+ SY YT ++ + W V + L Q Sbjct: 153 LRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYW--RGGDKAVTGVERIELPQ 210 Query: 218 YDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 277 + ++ + S V +TG Y ++ F LKR IGYF++QTY+P I+ ILS VSFW+N + Sbjct: 211 FSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYD 270 Query: 278 SVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNY- 336 + AR G+TTVLTMTT++ R +LPK+ Y A+D ++ C+ FVF AL+E+A VNY Sbjct: 271 ASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYI 330 Query: 337 FTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAP-------TATSYTPNLARGDPGLATI 389 F RG K + EK K K+ K + T+ + G+ Sbjct: 331 FFGRGPQRQKK--LAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDT 388 Query: 390 AKSATIEPK---EVKPETKPPE------------PKKT---------------FNSVSKI 419 SA + + ++ P E KKT V+ I Sbjct: 389 RNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAI 448 Query: 420 DRLSRIAFPLLFGIFNLVYWATYLN 444 DR SRI FP F +FNLVYW Y+N Sbjct: 449 DRWSRIVFPFTFSLFNLVYWLYYVN 473 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.135 0.413 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,151,710 Number of Sequences: 37866 Number of extensions: 715874 Number of successful extensions: 2044 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 64 Number of HSP's successfully gapped in prelim test: 15 Number of HSP's that attempted gapping in prelim test: 1858 Number of HSP's gapped (non-prelim): 155 length of query: 456 length of database: 18,247,518 effective HSP length: 106 effective length of query: 350 effective length of database: 14,233,722 effective search space: 4981802700 effective search space used: 4981802700 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.