Guide to the Human Genome
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Search of human proteins with 38202257

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38202257 neutral alpha-glucosidase AB isoform 2 [Homo
sapiens]
         (944 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38202257 neutral alpha-glucosidase AB isoform 2 [Homo sapiens]    1957   0.0  
gi|88900491 neutral alpha-glucosidase AB isoform 3 [Homo sapiens]    1944   0.0  
gi|66346737 glucosidase, alpha; neutral C [Homo sapiens]              959   0.0  
gi|119393895 acid alpha-glucosidase preproprotein [Homo sapiens]      328   1e-89
gi|119393893 acid alpha-glucosidase preproprotein [Homo sapiens]      328   1e-89
gi|119393891 acid alpha-glucosidase preproprotein [Homo sapiens]      328   1e-89
gi|221316699 maltase-glucoamylase [Homo sapiens]                      281   2e-75
gi|157364974 sucrase-isomaltase [Homo sapiens]                        277   3e-74
gi|169171979 PREDICTED: similar to sucrase-isomaltase [Homo sapi...   253   8e-67
gi|153791946 hypothetical protein LOC57462 [Homo sapiens]              77   8e-14
gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens]                 33   0.96 
gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens]                  33   0.96 
gi|7706589 GNAS complex locus NESP55 [Homo sapiens]                    33   1.3  
gi|157885806 chromosome 12 open reading frame 51 [Homo sapiens]        33   1.3  
gi|157743252 pecanex-like 3 [Homo sapiens]                             33   1.6  
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa...    32   2.1  
gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B ...    32   2.1  
gi|21389567 chemokine-like factor superfamily 2 [Homo sapiens]         32   2.8  
gi|83716024 kinesin family member 21B [Homo sapiens]                   32   2.8  
gi|12751473 DNA cytosine methyltransferase 3 alpha isoform a [Ho...    32   3.6  
gi|28559071 DNA cytosine methyltransferase 3 alpha isoform c [Ho...    32   3.6  
gi|28559069 DNA cytosine methyltransferase 3 alpha isoform a [Ho...    32   3.6  
gi|50428933 C1q domain containing 1 isoform 1 [Homo sapiens]           32   3.6  
gi|50428931 C1q domain containing 1 isoform 3 [Homo sapiens]           32   3.6  
gi|23503235 C1q domain containing 1 isoform 2 [Homo sapiens]           32   3.6  
gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens]                 31   4.8  
gi|47106061 KRAB-A domain containing 2 [Homo sapiens]                  31   4.8  
gi|126723149 chromosome 19 open reading frame 29 [Homo sapiens]        31   6.2  
gi|122937392 chromosome 19 open reading frame 29 [Homo sapiens]        31   6.2  
gi|239756047 PREDICTED: heparan sulfate 6-O-sulfotransferase 3 [...    30   8.1  

>gi|38202257 neutral alpha-glucosidase AB isoform 2 [Homo sapiens]
          Length = 944

 Score = 1957 bits (5069), Expect = 0.0
 Identities = 944/944 (100%), Positives = 944/944 (100%)

Query: 1   MAAVAAVAARRRRSWASLVLAFLGVCLGITLAVDRSNFKTCEESSFCKRQRSIRPGLSPY 60
           MAAVAAVAARRRRSWASLVLAFLGVCLGITLAVDRSNFKTCEESSFCKRQRSIRPGLSPY
Sbjct: 1   MAAVAAVAARRRRSWASLVLAFLGVCLGITLAVDRSNFKTCEESSFCKRQRSIRPGLSPY 60

Query: 61  RALLDSLQLGPDSLTVHLIHEVTKVLLVLELQGLQKNMTRFRIDELEPRRPRYRVPDVLV 120
           RALLDSLQLGPDSLTVHLIHEVTKVLLVLELQGLQKNMTRFRIDELEPRRPRYRVPDVLV
Sbjct: 61  RALLDSLQLGPDSLTVHLIHEVTKVLLVLELQGLQKNMTRFRIDELEPRRPRYRVPDVLV 120

Query: 121 ADPPIARLSVSGRDENSVELTMAEGPYKIILTARPFRLDLLEDRSLLLSVNARGLLEFEH 180
           ADPPIARLSVSGRDENSVELTMAEGPYKIILTARPFRLDLLEDRSLLLSVNARGLLEFEH
Sbjct: 121 ADPPIARLSVSGRDENSVELTMAEGPYKIILTARPFRLDLLEDRSLLLSVNARGLLEFEH 180

Query: 181 QRAPRVSQGSKDPAEGDGAQPEETPRDGDKPEETQGKAEKDEPGAWEETFKTHSDSKPYG 240
           QRAPRVSQGSKDPAEGDGAQPEETPRDGDKPEETQGKAEKDEPGAWEETFKTHSDSKPYG
Sbjct: 181 QRAPRVSQGSKDPAEGDGAQPEETPRDGDKPEETQGKAEKDEPGAWEETFKTHSDSKPYG 240

Query: 241 PMSVGLDFSLPGMEHVYGIPEHADNLRLKVTEGGEPYRLYNLDVFQYELYNPMALYGSVP 300
           PMSVGLDFSLPGMEHVYGIPEHADNLRLKVTEGGEPYRLYNLDVFQYELYNPMALYGSVP
Sbjct: 241 PMSVGLDFSLPGMEHVYGIPEHADNLRLKVTEGGEPYRLYNLDVFQYELYNPMALYGSVP 300

Query: 301 VLLAHNPHRDLGIFWLNAAETWVDISSNTAGKTLFGKMMDYLQGSGETPQTDVRWMSETG 360
           VLLAHNPHRDLGIFWLNAAETWVDISSNTAGKTLFGKMMDYLQGSGETPQTDVRWMSETG
Sbjct: 301 VLLAHNPHRDLGIFWLNAAETWVDISSNTAGKTLFGKMMDYLQGSGETPQTDVRWMSETG 360

Query: 361 IIDVFLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHN 420
           IIDVFLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHN
Sbjct: 361 IIDVFLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHN 420

Query: 421 LPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVDPHIKVDSGYRVH 480
           LPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVDPHIKVDSGYRVH
Sbjct: 421 LPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVDPHIKVDSGYRVH 480

Query: 481 EELRNLGLYVKTRDGSDYEGWCWPGSAGYPDFTNPTMRAWWANMFSYDNYEGSAPNLFVW 540
           EELRNLGLYVKTRDGSDYEGWCWPGSAGYPDFTNPTMRAWWANMFSYDNYEGSAPNLFVW
Sbjct: 481 EELRNLGLYVKTRDGSDYEGWCWPGSAGYPDFTNPTMRAWWANMFSYDNYEGSAPNLFVW 540

Query: 541 NDMNEPSVFNGPEVTMLKDAQHYGGWEHRDVHNIYGLYVHMATADGLRQRSGGMERPFVL 600
           NDMNEPSVFNGPEVTMLKDAQHYGGWEHRDVHNIYGLYVHMATADGLRQRSGGMERPFVL
Sbjct: 541 NDMNEPSVFNGPEVTMLKDAQHYGGWEHRDVHNIYGLYVHMATADGLRQRSGGMERPFVL 600

Query: 601 ARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLGLVGLSFCGADVGGFFKNPEPELL 660
           ARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLGLVGLSFCGADVGGFFKNPEPELL
Sbjct: 601 ARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLGLVGLSFCGADVGGFFKNPEPELL 660

Query: 661 VRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDIIRDALGQRYSLLPFWYTLLYQAHR 720
           VRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDIIRDALGQRYSLLPFWYTLLYQAHR
Sbjct: 661 VRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDIIRDALGQRYSLLPFWYTLLYQAHR 720

Query: 721 EGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQVYLPGQGEVWYDIQ 780
           EGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQVYLPGQGEVWYDIQ
Sbjct: 721 EGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQVYLPGQGEVWYDIQ 780

Query: 781 SYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSECMKDDPITLFVALSPQGTA 840
           SYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSECMKDDPITLFVALSPQGTA
Sbjct: 781 SYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSECMKDDPITLFVALSPQGTA 840

Query: 841 QGELFLDDGHTFNYQTRQEFLLRRFSFSGNTLVSSSADPEGHFETPIWIERVVIIGAGKP 900
           QGELFLDDGHTFNYQTRQEFLLRRFSFSGNTLVSSSADPEGHFETPIWIERVVIIGAGKP
Sbjct: 841 QGELFLDDGHTFNYQTRQEFLLRRFSFSGNTLVSSSADPEGHFETPIWIERVVIIGAGKP 900

Query: 901 AAVVLQTKGSPESRLSFQHDPETSVLVLRKPGINVASDWSIHLR 944
           AAVVLQTKGSPESRLSFQHDPETSVLVLRKPGINVASDWSIHLR
Sbjct: 901 AAVVLQTKGSPESRLSFQHDPETSVLVLRKPGINVASDWSIHLR 944


>gi|88900491 neutral alpha-glucosidase AB isoform 3 [Homo sapiens]
          Length = 966

 Score = 1944 bits (5036), Expect = 0.0
 Identities = 944/966 (97%), Positives = 944/966 (97%), Gaps = 22/966 (2%)

Query: 1   MAAVAAVAARRRRSWASLVLAFLGVCLGITLAVDRSNFKTCEESSFCKRQRSIRPGLSPY 60
           MAAVAAVAARRRRSWASLVLAFLGVCLGITLAVDRSNFKTCEESSFCKRQRSIRPGLSPY
Sbjct: 1   MAAVAAVAARRRRSWASLVLAFLGVCLGITLAVDRSNFKTCEESSFCKRQRSIRPGLSPY 60

Query: 61  RALLDSLQLGPDSLTVHLIHEVTKVLLVLELQGLQKNMTRFRIDELEPRRPRYRVPDVLV 120
           RALLDSLQLGPDSLTVHLIHEVTKVLLVLELQGLQKNMTRFRIDELEPRRPRYRVPDVLV
Sbjct: 61  RALLDSLQLGPDSLTVHLIHEVTKVLLVLELQGLQKNMTRFRIDELEPRRPRYRVPDVLV 120

Query: 121 ADPPIARLSVSGRDENSVELTMAEGPYKIILTARPFRLDLLEDRSLLLSVNARGLLEFEH 180
           ADPPIARLSVSGRDENSVELTMAEGPYKIILTARPFRLDLLEDRSLLLSVNARGLLEFEH
Sbjct: 121 ADPPIARLSVSGRDENSVELTMAEGPYKIILTARPFRLDLLEDRSLLLSVNARGLLEFEH 180

Query: 181 QRAPRVS----------------------QGSKDPAEGDGAQPEETPRDGDKPEETQGKA 218
           QRAPRVS                      QGSKDPAEGDGAQPEETPRDGDKPEETQGKA
Sbjct: 181 QRAPRVSFSDKVNLTLGSIWDKIKNLFSRQGSKDPAEGDGAQPEETPRDGDKPEETQGKA 240

Query: 219 EKDEPGAWEETFKTHSDSKPYGPMSVGLDFSLPGMEHVYGIPEHADNLRLKVTEGGEPYR 278
           EKDEPGAWEETFKTHSDSKPYGPMSVGLDFSLPGMEHVYGIPEHADNLRLKVTEGGEPYR
Sbjct: 241 EKDEPGAWEETFKTHSDSKPYGPMSVGLDFSLPGMEHVYGIPEHADNLRLKVTEGGEPYR 300

Query: 279 LYNLDVFQYELYNPMALYGSVPVLLAHNPHRDLGIFWLNAAETWVDISSNTAGKTLFGKM 338
           LYNLDVFQYELYNPMALYGSVPVLLAHNPHRDLGIFWLNAAETWVDISSNTAGKTLFGKM
Sbjct: 301 LYNLDVFQYELYNPMALYGSVPVLLAHNPHRDLGIFWLNAAETWVDISSNTAGKTLFGKM 360

Query: 339 MDYLQGSGETPQTDVRWMSETGIIDVFLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQ 398
           MDYLQGSGETPQTDVRWMSETGIIDVFLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQ
Sbjct: 361 MDYLQGSGETPQTDVRWMSETGIIDVFLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQ 420

Query: 399 SRWNYRDEADVLEVDQGFDDHNLPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLAS 458
           SRWNYRDEADVLEVDQGFDDHNLPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLAS
Sbjct: 421 SRWNYRDEADVLEVDQGFDDHNLPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLAS 480

Query: 459 KRRKLVAIVDPHIKVDSGYRVHEELRNLGLYVKTRDGSDYEGWCWPGSAGYPDFTNPTMR 518
           KRRKLVAIVDPHIKVDSGYRVHEELRNLGLYVKTRDGSDYEGWCWPGSAGYPDFTNPTMR
Sbjct: 481 KRRKLVAIVDPHIKVDSGYRVHEELRNLGLYVKTRDGSDYEGWCWPGSAGYPDFTNPTMR 540

Query: 519 AWWANMFSYDNYEGSAPNLFVWNDMNEPSVFNGPEVTMLKDAQHYGGWEHRDVHNIYGLY 578
           AWWANMFSYDNYEGSAPNLFVWNDMNEPSVFNGPEVTMLKDAQHYGGWEHRDVHNIYGLY
Sbjct: 541 AWWANMFSYDNYEGSAPNLFVWNDMNEPSVFNGPEVTMLKDAQHYGGWEHRDVHNIYGLY 600

Query: 579 VHMATADGLRQRSGGMERPFVLARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLGL 638
           VHMATADGLRQRSGGMERPFVLARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLGL
Sbjct: 601 VHMATADGLRQRSGGMERPFVLARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLGL 660

Query: 639 VGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDIIR 698
           VGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDIIR
Sbjct: 661 VGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDIIR 720

Query: 699 DALGQRYSLLPFWYTLLYQAHREGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPVS 758
           DALGQRYSLLPFWYTLLYQAHREGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPVS
Sbjct: 721 DALGQRYSLLPFWYTLLYQAHREGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPVS 780

Query: 759 DSGAHGVQVYLPGQGEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRR 818
           DSGAHGVQVYLPGQGEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRR
Sbjct: 781 DSGAHGVQVYLPGQGEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRR 840

Query: 819 SSECMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRQEFLLRRFSFSGNTLVSSSAD 878
           SSECMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRQEFLLRRFSFSGNTLVSSSAD
Sbjct: 841 SSECMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRQEFLLRRFSFSGNTLVSSSAD 900

Query: 879 PEGHFETPIWIERVVIIGAGKPAAVVLQTKGSPESRLSFQHDPETSVLVLRKPGINVASD 938
           PEGHFETPIWIERVVIIGAGKPAAVVLQTKGSPESRLSFQHDPETSVLVLRKPGINVASD
Sbjct: 901 PEGHFETPIWIERVVIIGAGKPAAVVLQTKGSPESRLSFQHDPETSVLVLRKPGINVASD 960

Query: 939 WSIHLR 944
           WSIHLR
Sbjct: 961 WSIHLR 966


>gi|66346737 glucosidase, alpha; neutral C [Homo sapiens]
          Length = 914

 Score =  959 bits (2480), Expect = 0.0
 Identities = 458/913 (50%), Positives = 633/913 (69%), Gaps = 15/913 (1%)

Query: 32  AVDRSNFKTCEESSFCKRQRSIRPGLSPYRALLDSLQLGPDSLTVHLIHEVTKVLLVLEL 91
           AVD++ F+ C + +F +RQ+      S Y+ALLDS+    DS    +I+E +KV L+ E+
Sbjct: 15  AVDKNIFRDCNKIAFYRRQKQWLSKKSTYQALLDSVTTDEDSTRFQIINEASKVPLLAEI 74

Query: 92  QGLQKNMTRFRIDELEPRRPRYRVPDVLVADPPIARLSVSGRDENSVELTMAEGPYKIIL 151
            G++ N+ R +I+E  P +PR+ VPDVL + P   RL     D  S+ L   +G  K  +
Sbjct: 75  YGIEGNIFRLKINEETPLKPRFEVPDVLTSKPSTVRLISCSGDTGSLILADGKGDLKCHI 134

Query: 152 TARPFRLDLLEDRSLLLSVNARGLLEFEHQRAPRVSQGSKDPAEGDGAQPEETPRDGDKP 211
           TA PF++DL+ +  +++S+N+ G L FEH +     + +K+         EET  D  + 
Sbjct: 135 TANPFKVDLVSEEEVVISINSLGQLYFEHLQILHKQRAAKE-------NEEETSVDTSQE 187

Query: 212 EETQGKAEKDEPGAWEETFKTHSDSKPYGPMSVGLDFSLPGMEHVYGIPEHADNLRLKVT 271
            +       ++ G WEE F    D K  GP S+GLDFSL G EH+YGIP+HA++ +LK T
Sbjct: 188 NQ-------EDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGIPQHAESHQLKNT 240

Query: 272 EGGEPYRLYNLDVFQYELYNPMALYGSVPVLLAHNPHRDLGIFWLNAAETWVDISSNTAG 331
             G+ YRLYNLDV+ Y++Y+ M +YGSVP LLAH   R +GIFWLNA+ET V+I++  A 
Sbjct: 241 GDGDAYRLYNLDVYGYQIYDKMGIYGSVPYLLAHKLGRTIGIFWLNASETLVEINTEPAV 300

Query: 332 KTLFGKMMDYLQGSGETPQTDVRWMSETGIIDVFLLLGPSISDVFRQYASLTGTQALPPL 391
           +    +M           +T V WMSE+GIIDVFLL GP+ SDVF+QY+ LTGTQA+PPL
Sbjct: 301 EYTLTQMGPVAAKQKVRSRTHVHWMSESGIIDVFLLTGPTPSDVFKQYSHLTGTQAMPPL 360

Query: 392 FSLGYHQSRWNYRDEADVLEVDQGFDDHNLPCDVIWLDIEHADGKRYFTWDPSRFPQPRT 451
           FSLGYHQ RWNY DE DV  VD GFD+H++P D +WLDIEH +GKRYFTWD +RFP P+ 
Sbjct: 361 FSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDAMWLDIEHTEGKRYFTWDKNRFPNPKR 420

Query: 452 MLERLASKRRKLVAIVDPHIKVDSGYRVHEELRNLGLYVKTRDGSDYEGWCWPGSAGYPD 511
           M E L SK+RKLV I DPHIK+D  Y V+ + ++ G +VK ++G D+EG CWPG + Y D
Sbjct: 421 MQELLRSKKRKLVVISDPHIKIDPDYSVYVKAKDQGFFVKNQEGEDFEGVCWPGLSSYLD 480

Query: 512 FTNPTMRAWWANMFSYDNYEGSAPNLFVWNDMNEPSVFNGPEVTMLKDAQHYGGWEHRDV 571
           FTNP +R W++++F++  Y+GS   LF+WNDMNEPSVF GPE TM K+A H+G WEHR++
Sbjct: 481 FTNPKVREWYSSLFAFPVYQGSTDILFLWNDMNEPSVFRGPEQTMQKNAIHHGNWEHREL 540

Query: 572 HNIYGLYVHMATADGLRQRSGGMERPFVLARAFFAGSQRFGAVWTGDNTAEWDHLKISIP 631
           HNIYG Y  MATA+GL +RS G ERPFVL R+FFAGSQ++GAVWTGDNTAEW +LKISIP
Sbjct: 541 HNIYGFYHQMATAEGLIKRSKGKERPFVLTRSFFAGSQKYGAVWTGDNTAEWSNLKISIP 600

Query: 632 MCLSLGLVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLPS 691
           M L+L + G+SFCGAD+GGF  NPE ELLVRWYQ GAYQPFFR HA ++T RREPWL   
Sbjct: 601 MLLTLSITGISFCGADIGGFIGNPETELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGE 660

Query: 692 QHNDIIRDALGQRYSLLPFWYTLLYQAHREGIPVMRPLWVQYPQDVTTFNIDDQYLLGDA 751
           +H  +IR+A+ +RY LLP+WY+L Y AH    PVMRPLWV++P ++ TF+++D+Y+LG A
Sbjct: 661 EHTRLIREAIRERYGLLPYWYSLFYHAHVASQPVMRPLWVEFPDELKTFDMEDEYMLGSA 720

Query: 752 LLVHPVSDSGAHGVQVYLPGQGEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVP 811
           LLVHPV++  A  V V+LPG  EVWYD +++    G  T+ +PV L +IPVFQRGG+++P
Sbjct: 721 LLVHPVTEPKATTVDVFLPGSNEVWYDYKTFAHWEGGCTVKIPVALDTIPVFQRGGSVIP 780

Query: 812 RWMRVRRSSECMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRQEFLLRRFSFSGNT 871
               V +S+  M +    L VALS +G++ GEL+LDDGH+F Y  +++FL R+FSF  + 
Sbjct: 781 IKTTVGKSTGWMTESSYGLRVALSTKGSSVGELYLDDGHSFQYLHQKQFLHRKFSFCSSV 840

Query: 872 LVSSSADPEGHFETPIWIERVVIIGAGK-PAAVVLQTKGSPESRLSFQHDPETSVLVLRK 930
           L++S AD  GH+ +   +E+++++G  K P++V   +    +  ++F +  +TS+L L K
Sbjct: 841 LINSFADQRGHYPSKCVVEKILVLGFRKEPSSVTTHSSDGKDQPVAFTYCAKTSILSLEK 900

Query: 931 PGINVASDWSIHL 943
             +N+A+DW + +
Sbjct: 901 LSLNIATDWEVRI 913


>gi|119393895 acid alpha-glucosidase preproprotein [Homo sapiens]
          Length = 952

 Score =  328 bits (842), Expect = 1e-89
 Identities = 238/729 (32%), Positives = 339/729 (46%), Gaps = 89/729 (12%)

Query: 246 LDFSLPGMEHVYGIPEHADNLRLKVTEGGEPYRLYNLDVFQYELYNPMALYGSVPVLLAH 305
           L  SLP  +++ G+ EH   L L  +       L+N D+      N   LYGS P  LA 
Sbjct: 248 LSTSLPS-QYITGLAEHLSPLMLSTS--WTRITLWNRDLAPTPGAN---LYGSHPFYLAL 301

Query: 306 NPHRDL-GIFWLNAAETWVDISSNTAGKTLFGKMMDYLQGSGETPQTDVRWMSETGIIDV 364
                  G+F LN         SN     L              P   + W S  GI+DV
Sbjct: 302 EDGGSAHGVFLLN---------SNAMDVVL-------------QPSPALSWRSTGGILDV 339

Query: 365 FLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNLPCD 424
           ++ LGP    V +QY  + G   +PP + LG+H  RW Y   A   +V +     + P D
Sbjct: 340 YIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLD 399

Query: 425 VIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVDPHIKVDS---GYRVHE 481
           V W D+++ D +R FT++   F     M++ L    R+ + IVDP I        YR ++
Sbjct: 400 VQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYD 459

Query: 482 ELRNLGLYVKTRDGSDYEGWCWPGSAGYPDFTNPTMRAWWANMFSYDNYEGSAPNLFVWN 541
           E    G+++    G    G  WPGS  +PDFTNPT  AWW +M +   +    P   +W 
Sbjct: 460 EGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVA--EFHDQVPFDGMWI 517

Query: 542 DMNEPSVF--------------NGPEV----------TMLKDAQHYGGWEHRDVHNIYGL 577
           DMNEPS F              N P V            +  + H     H ++HN+YGL
Sbjct: 518 DMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGL 577

Query: 578 YVHMATADGLRQRSGGMERPFVLARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLG 637
              +A+   L +  G   RPFV++R+ FAG  R+   WTGD  + W+ L  S+P  L   
Sbjct: 578 TEAIASHRALVKARG--TRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFN 635

Query: 638 LVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDII 697
           L+G+   GADV GF  N   EL VRW Q+GA+ PF R H  L +  +EP+         +
Sbjct: 636 LLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAM 695

Query: 698 RDALGQRYSLLPFWYTLLYQAHREGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPV 757
           R AL  RY+LLP  YTL +QAH  G  V RPL++++P+D +T+ +D Q L G+ALL+ PV
Sbjct: 696 RKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPV 755

Query: 758 SDSGAHGVQVYLPGQGEVWYDIQSYQK------------------HHGPQTLYLPVTLSS 799
             +G   V  Y P     WYD+Q+                     H   Q + LP  L +
Sbjct: 756 LQAGKAEVTGYFP--LGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDT 813

Query: 800 IPVFQRGGTIVPRWMRVRRSSECMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRQE 859
           I V  R G I+P       ++E  +  P+ L VAL+  G A+GELF DDG +     R  
Sbjct: 814 INVHLRAGYIIPLQGPGLTTTE-SRQQPMALAVALTKGGEARGELFWDDGESLEVLERGA 872

Query: 860 FLLRRFSFSGNTLVSS--SADPEGHFETPIWIERVVIIGAGKPAAVVLQTKGSPESRLSF 917
           +    F    NT+V+       EG     + +++V ++G       VL + G P S  +F
Sbjct: 873 YTQVIFLARNNTIVNELVRVTSEG---AGLQLQKVTVLGVATAPQQVL-SNGVPVS--NF 926

Query: 918 QHDPETSVL 926
            + P+T VL
Sbjct: 927 TYSPDTKVL 935


>gi|119393893 acid alpha-glucosidase preproprotein [Homo sapiens]
          Length = 952

 Score =  328 bits (842), Expect = 1e-89
 Identities = 238/729 (32%), Positives = 339/729 (46%), Gaps = 89/729 (12%)

Query: 246 LDFSLPGMEHVYGIPEHADNLRLKVTEGGEPYRLYNLDVFQYELYNPMALYGSVPVLLAH 305
           L  SLP  +++ G+ EH   L L  +       L+N D+      N   LYGS P  LA 
Sbjct: 248 LSTSLPS-QYITGLAEHLSPLMLSTS--WTRITLWNRDLAPTPGAN---LYGSHPFYLAL 301

Query: 306 NPHRDL-GIFWLNAAETWVDISSNTAGKTLFGKMMDYLQGSGETPQTDVRWMSETGIIDV 364
                  G+F LN         SN     L              P   + W S  GI+DV
Sbjct: 302 EDGGSAHGVFLLN---------SNAMDVVL-------------QPSPALSWRSTGGILDV 339

Query: 365 FLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNLPCD 424
           ++ LGP    V +QY  + G   +PP + LG+H  RW Y   A   +V +     + P D
Sbjct: 340 YIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLD 399

Query: 425 VIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVDPHIKVDS---GYRVHE 481
           V W D+++ D +R FT++   F     M++ L    R+ + IVDP I        YR ++
Sbjct: 400 VQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYD 459

Query: 482 ELRNLGLYVKTRDGSDYEGWCWPGSAGYPDFTNPTMRAWWANMFSYDNYEGSAPNLFVWN 541
           E    G+++    G    G  WPGS  +PDFTNPT  AWW +M +   +    P   +W 
Sbjct: 460 EGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVA--EFHDQVPFDGMWI 517

Query: 542 DMNEPSVF--------------NGPEV----------TMLKDAQHYGGWEHRDVHNIYGL 577
           DMNEPS F              N P V            +  + H     H ++HN+YGL
Sbjct: 518 DMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGL 577

Query: 578 YVHMATADGLRQRSGGMERPFVLARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLG 637
              +A+   L +  G   RPFV++R+ FAG  R+   WTGD  + W+ L  S+P  L   
Sbjct: 578 TEAIASHRALVKARG--TRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFN 635

Query: 638 LVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDII 697
           L+G+   GADV GF  N   EL VRW Q+GA+ PF R H  L +  +EP+         +
Sbjct: 636 LLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAM 695

Query: 698 RDALGQRYSLLPFWYTLLYQAHREGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPV 757
           R AL  RY+LLP  YTL +QAH  G  V RPL++++P+D +T+ +D Q L G+ALL+ PV
Sbjct: 696 RKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPV 755

Query: 758 SDSGAHGVQVYLPGQGEVWYDIQSYQK------------------HHGPQTLYLPVTLSS 799
             +G   V  Y P     WYD+Q+                     H   Q + LP  L +
Sbjct: 756 LQAGKAEVTGYFP--LGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDT 813

Query: 800 IPVFQRGGTIVPRWMRVRRSSECMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRQE 859
           I V  R G I+P       ++E  +  P+ L VAL+  G A+GELF DDG +     R  
Sbjct: 814 INVHLRAGYIIPLQGPGLTTTE-SRQQPMALAVALTKGGEARGELFWDDGESLEVLERGA 872

Query: 860 FLLRRFSFSGNTLVSS--SADPEGHFETPIWIERVVIIGAGKPAAVVLQTKGSPESRLSF 917
           +    F    NT+V+       EG     + +++V ++G       VL + G P S  +F
Sbjct: 873 YTQVIFLARNNTIVNELVRVTSEG---AGLQLQKVTVLGVATAPQQVL-SNGVPVS--NF 926

Query: 918 QHDPETSVL 926
            + P+T VL
Sbjct: 927 TYSPDTKVL 935


>gi|119393891 acid alpha-glucosidase preproprotein [Homo sapiens]
          Length = 952

 Score =  328 bits (842), Expect = 1e-89
 Identities = 238/729 (32%), Positives = 339/729 (46%), Gaps = 89/729 (12%)

Query: 246 LDFSLPGMEHVYGIPEHADNLRLKVTEGGEPYRLYNLDVFQYELYNPMALYGSVPVLLAH 305
           L  SLP  +++ G+ EH   L L  +       L+N D+      N   LYGS P  LA 
Sbjct: 248 LSTSLPS-QYITGLAEHLSPLMLSTS--WTRITLWNRDLAPTPGAN---LYGSHPFYLAL 301

Query: 306 NPHRDL-GIFWLNAAETWVDISSNTAGKTLFGKMMDYLQGSGETPQTDVRWMSETGIIDV 364
                  G+F LN         SN     L              P   + W S  GI+DV
Sbjct: 302 EDGGSAHGVFLLN---------SNAMDVVL-------------QPSPALSWRSTGGILDV 339

Query: 365 FLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNLPCD 424
           ++ LGP    V +QY  + G   +PP + LG+H  RW Y   A   +V +     + P D
Sbjct: 340 YIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLD 399

Query: 425 VIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVDPHIKVDS---GYRVHE 481
           V W D+++ D +R FT++   F     M++ L    R+ + IVDP I        YR ++
Sbjct: 400 VQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYD 459

Query: 482 ELRNLGLYVKTRDGSDYEGWCWPGSAGYPDFTNPTMRAWWANMFSYDNYEGSAPNLFVWN 541
           E    G+++    G    G  WPGS  +PDFTNPT  AWW +M +   +    P   +W 
Sbjct: 460 EGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVA--EFHDQVPFDGMWI 517

Query: 542 DMNEPSVF--------------NGPEV----------TMLKDAQHYGGWEHRDVHNIYGL 577
           DMNEPS F              N P V            +  + H     H ++HN+YGL
Sbjct: 518 DMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGL 577

Query: 578 YVHMATADGLRQRSGGMERPFVLARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLG 637
              +A+   L +  G   RPFV++R+ FAG  R+   WTGD  + W+ L  S+P  L   
Sbjct: 578 TEAIASHRALVKARG--TRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFN 635

Query: 638 LVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDII 697
           L+G+   GADV GF  N   EL VRW Q+GA+ PF R H  L +  +EP+         +
Sbjct: 636 LLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAM 695

Query: 698 RDALGQRYSLLPFWYTLLYQAHREGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPV 757
           R AL  RY+LLP  YTL +QAH  G  V RPL++++P+D +T+ +D Q L G+ALL+ PV
Sbjct: 696 RKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPV 755

Query: 758 SDSGAHGVQVYLPGQGEVWYDIQSYQK------------------HHGPQTLYLPVTLSS 799
             +G   V  Y P     WYD+Q+                     H   Q + LP  L +
Sbjct: 756 LQAGKAEVTGYFP--LGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDT 813

Query: 800 IPVFQRGGTIVPRWMRVRRSSECMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRQE 859
           I V  R G I+P       ++E  +  P+ L VAL+  G A+GELF DDG +     R  
Sbjct: 814 INVHLRAGYIIPLQGPGLTTTE-SRQQPMALAVALTKGGEARGELFWDDGESLEVLERGA 872

Query: 860 FLLRRFSFSGNTLVSS--SADPEGHFETPIWIERVVIIGAGKPAAVVLQTKGSPESRLSF 917
           +    F    NT+V+       EG     + +++V ++G       VL + G P S  +F
Sbjct: 873 YTQVIFLARNNTIVNELVRVTSEG---AGLQLQKVTVLGVATAPQQVL-SNGVPVS--NF 926

Query: 918 QHDPETSVL 926
            + P+T VL
Sbjct: 927 TYSPDTKVL 935


>gi|221316699 maltase-glucoamylase [Homo sapiens]
          Length = 1857

 Score =  281 bits (719), Expect = 2e-75
 Identities = 198/635 (31%), Positives = 310/635 (48%), Gaps = 47/635 (7%)

Query: 349 PQTDVRWMSETGIIDVFLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEAD 408
           P   + + +  GI+D ++ LG +   V ++Y  L G  ALP  ++LG+H SR+ Y    +
Sbjct: 333 PAPAITYRTIGGILDFYVFLGNTPEQVVQEYLELIGRPALPSYWALGFHLSRYEYGTLDN 392

Query: 409 VLEVDQGFDDHNLPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVD 468
           + EV +      LP DV   DI++ D +R FT+D   F      +  L +  +KLV IVD
Sbjct: 393 MREVVERNRAAQLPYDVQHADIDYMDERRDFTYDSVDFKGFPEFVNELHNNGQKLVIIVD 452

Query: 469 PHIKVDSG----YRVHEELRNLGLYVKTRDG-SDYEGWCWPGSAGYPDFTNPTMRAWWAN 523
           P I  +S     Y  ++   ++ ++V + DG +   G  WPG   +PD+TNP    WW  
Sbjct: 453 PAISNNSSSSKPYGPYDRGSDMKIWVNSSDGVTPLIGEVWPGQTVFPDYTNPNCAVWWTK 512

Query: 524 MFSYDNYEGSAPNLFVWNDMNEPSVF-------------NGPEVT------------MLK 558
            F   + +       +W DMNE S F             N P  T            +  
Sbjct: 513 EFELFHNQVEFDG--IWIDMNEVSNFVDGSVSGCSTNNLNNPPFTPRILDGYLFCKTLCM 570

Query: 559 DA-QHYGGWEHRDVHNIYGLYVHMATADGLRQRSGGMERPFVLARAFFAGSQRFGAVWTG 617
           DA QH+G  +  D+HN+YG  + +ATA+  +      +R F+L R+ FAGS +F A W G
Sbjct: 571 DAVQHWG--KQYDIHNLYGYSMAVATAEAAKTVFPN-KRSFILTRSTFAGSGKFAAHWLG 627

Query: 618 DNTAEWDHLKISIPMCLSLGLVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHA 677
           DNTA WD L+ SIP  L   L G+   G D+ GF  +   EL  RW Q+GA+ PF R H 
Sbjct: 628 DNTATWDDLRWSIPGVLEFNLFGIPMVGPDICGFALDTPEELCRRWMQLGAFYPFSRNHN 687

Query: 678 HLDTGRREP--WLLPSQHNDIIRDALGQRYSLLPFWYTLLYQAHREGIPVMRPLWVQYPQ 735
                 ++P  +   S   +  R  L  RY+LLP+ YTL ++AH  G  V RPL  ++ +
Sbjct: 688 GQGYKDQDPASFGADSLLLNSSRHYLNIRYTLLPYLYTLFFRAHSRGDTVARPLLHEFYE 747

Query: 736 DVTTFNIDDQYLLGDALLVHPVSDSGAHGVQVYLPGQGEVWYDIQS-YQKHHGPQTLYLP 794
           D +T+++  Q+L G  LL+ PV D GA  V  Y+P    VWYD ++  Q     Q + + 
Sbjct: 748 DNSTWDVHQQFLWGPGLLITPVLDEGAEKVMAYVP--DAVWYDYETGSQVRWRKQKVEME 805

Query: 795 VTLSSIPVFQRGGTIVPRWMRVRRSSECMKDDPITLFVALSPQGTAQGELFLDDGHTFNY 854
           +    I +  RGG I P   +   ++   + +P+ L +AL     A+GELF D+G T + 
Sbjct: 806 LPGDKIGLHLRGGYIFPT-QQPNTTTLASRKNPLGLIIALDENKEAKGELFWDNGETKDT 864

Query: 855 QTRQEFLLRRFSFSGNTLVSSSADPEGHFETPIWIERVVIIGAGKPAAVVLQTKGSP-ES 913
              + +LL  FS + N L  + +         +    + I+G  +P+ V ++  G P ++
Sbjct: 865 VANKVYLLCEFSVTQNRLEVNISQSTYKDPNNLAFNEIKILGTEEPSNVTVKHNGVPSQT 924

Query: 914 RLSFQHDPETSVLVLRKPGINVAS----DWSIHLR 944
             +  +D    V ++    + +      +WSI +R
Sbjct: 925 SPTVTYDSNLKVAIITDIDLLLGEAYTVEWSIKIR 959



 Score =  253 bits (646), Expect = 6e-67
 Identities = 193/652 (29%), Positives = 302/652 (46%), Gaps = 70/652 (10%)

Query: 349  PQTDVRWMSETGIIDVFLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEAD 408
            P   + + +  G++D ++ LGP+   V +QY  L G   + P +SLG+   R+ Y+++++
Sbjct: 1199 PLPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSE 1258

Query: 409  VLEVDQGFDDHNLPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVD 468
            +  +        +P DV + DI++ + +  FT  P +F     ++ R+ +   +++ I+D
Sbjct: 1259 IASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSP-KFAGFPALINRMKADGMRVILILD 1317

Query: 469  PHIKVDSGYRVHEELRNL--GLYVK-TRDGSDYEGWCWP--------GS----------- 506
            P I  +         R +   +++K   DG    G  WP        GS           
Sbjct: 1318 PAISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQVELYR 1377

Query: 507  --AGYPDFTNPTMRAWWANMFS--YDNYEGSAPNLF---VWNDMNEPSVF-NGPEVTMLK 558
                +PDF   +   WW       Y+N +    +L    +W DMNEPS F NG      +
Sbjct: 1378 AYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCR 1437

Query: 559  DAQ--------HYGGWE-----------------------HRDVHNIYGLYVHMATADGL 587
            DA         H    +                       H +VHN+YG      T + +
Sbjct: 1438 DASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRPTYEAV 1497

Query: 588  RQRSGGMERPFVLARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLGLVGLSFCGAD 647
            ++ +G  +R  V+ R+ F  S R+   W GDNTA WD LK SI   +   L G+S+ GAD
Sbjct: 1498 QEVTG--QRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGAD 1555

Query: 648  VGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDIIRDALGQRYSL 707
            + GFF++ E E+ VRW Q+GA+ PF R H  + T R++P        +I R  L  RY+L
Sbjct: 1556 ICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDVAFVNISRTVLQTRYTL 1615

Query: 708  LPFWYTLLYQAHREGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQV 767
            LP+ YTL+++AH EG+ V+RPL  ++  D  T++ID Q+LLG A LV PV +  A  V  
Sbjct: 1616 LPYLYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTA 1675

Query: 768  YLPGQGEVWYDIQS-YQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSECMKDD 826
            Y P     WYD  +    +   +   LP  L  I +  RGG I+P W     ++   +  
Sbjct: 1676 YFPRAR--WYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILP-WQEPALNTHLSRQK 1732

Query: 827  PITLFVALSPQGTAQGELFLDDGHTFNYQTRQEFLLRRFSFSGNTLVSSSADPEGHFET- 885
             +   +AL  +GTA G LF DDG + +   +  + L  FS S NT+ S          T 
Sbjct: 1733 FMGFKIALDDEGTAGGWLFWDDGQSIDTYGKGLYYLASFSASQNTMQSHIIFNNYITGTN 1792

Query: 886  PIWIERVVIIGAGK-PAAVVLQTKGSPESRLSFQHDPETSVLVLRKPGINVA 936
            P+ +  + I G G  P   V  +        SF +DP T VL +     N++
Sbjct: 1793 PLKLGYIEIWGVGSVPVTSVSISVSGMVITPSFNNDPTTQVLSIDVTDRNIS 1844


>gi|157364974 sucrase-isomaltase [Homo sapiens]
          Length = 1827

 Score =  277 bits (709), Expect = 3e-74
 Identities = 205/635 (32%), Positives = 305/635 (48%), Gaps = 55/635 (8%)

Query: 349 PQTDVRWMSETGIIDVFLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEAD 408
           P   V +    GI+D ++LLG +   V +QY  L G  A+P  ++LG+  SRWNY+    
Sbjct: 308 PTPIVTYRVTGGILDFYILLGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSRWNYKSLDV 367

Query: 409 VLEVDQGFDDHNLPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVD 468
           V EV +   +  +P D    DI++ + K+ FT+D   F      ++ L    +K V I+D
Sbjct: 368 VKEVVRRNREAGIPFDTQVTDIDYMEDKKDFTYDQVAFNGLPQFVQDLHDHGQKYVIILD 427

Query: 469 PHIKVD-----SGYRVHEELRNLGLYVKTRDGSD-YEGWCWPGSAGYPDFTNPTMRAWWA 522
           P I +      + Y  +E      +++   DGS    G  WPG   YPDFTNP    WWA
Sbjct: 428 PAISIGRRANGTTYATYERGNTQHVWINESDGSTPIIGEVWPGLTVYPDFTNPNCIDWWA 487

Query: 523 NMFSYDNYEGSAPNLFVWNDMNEPSVF-------------NGPEVT------------ML 557
           N  S  + E     L  W DMNE S F             N P  T            + 
Sbjct: 488 NECSIFHQEVQYDGL--WIDMNEVSSFIQGSTKGCNVNKLNYPPFTPDILDKLMYSKTIC 545

Query: 558 KDAQHYGGWEHRDVHNIYGLYVHMATADGLRQRSGGMERPFVLARAFFAGSQRFGAVWTG 617
            DA    G ++ DVH++YG  + +AT   + Q+    +R F+L R+ FAGS R  A W G
Sbjct: 546 MDAVQNWGKQY-DVHSLYGYSMAIATEQAV-QKVFPNKRSFILTRSTFAGSGRHAAHWLG 603

Query: 618 DNTAEWDHLKISIPMCLSLGLVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHA 677
           DNTA W+ ++ SI   L   L G+   GAD+ GF      EL  RW Q+GA+ PF R H 
Sbjct: 604 DNTASWEQMEWSITGMLEFSLFGIPLVGADICGFVAETTEELCRRWMQLGAFYPFSRNHN 663

Query: 678 HLDTGRREPWLLPSQHNDII---RDALGQRYSLLPFWYTLLYQAHREGIPVMRPLWVQYP 734
                 ++P     Q++ ++   R  L  RY+LLPF YTL Y+AH  G  V RP+  ++ 
Sbjct: 664 SDGYEHQDPAFF-GQNSLLVKSSRQYLTIRYTLLPFLYTLFYKAHVFGETVARPVLHEFY 722

Query: 735 QDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQVYLPGQGEVWYDIQSYQKHHGPQ---TL 791
           +D  ++  D ++L G ALL+ PV   GA  V  Y+P    +WYD +S  K    +    +
Sbjct: 723 EDTNSWIEDTEFLWGPALLITPVLKQGADTVSAYIP--DAIWYDYESGAKRPWRKQRVDM 780

Query: 792 YLPVTLSSIPVFQRGGTIVPRWMRVRRSSECMKDDPITLFVALSPQGTAQGELFLDDGHT 851
           YLP     I +  RGG I+P       ++   + +P+ L VAL    TA+G+ F DDG T
Sbjct: 781 YLPA--DKIGLHLRGGYIIP-IQEPDVTTTASRKNPLGLIVALGENNTAKGDFFWDDGET 837

Query: 852 FNYQTRQEFLLRRFSFSGNTL---VSSSADPEGHFETPIWIERVVIIGAGKPAAVVLQTK 908
            +      ++L  FS S NTL    + S+  EG   T +  + V I+G       V   +
Sbjct: 838 KDTIQNGNYILYTFSVSNNTLDIVCTHSSYQEG---TTLAFQTVKILGLTDSVTEVRVAE 894

Query: 909 GSP--ESRLSFQHDPETSVLVLRKPGINVASDWSI 941
            +    +  +F +D    VL++    +N+  ++S+
Sbjct: 895 NNQPMNAHSNFTYDASNQVLLIADLKLNLGRNFSV 929



 Score =  221 bits (563), Expect = 2e-57
 Identities = 176/657 (26%), Positives = 292/657 (44%), Gaps = 73/657 (11%)

Query: 349  PQTDVRWMSETGIIDVFLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEAD 408
            P   + + +  GI+D ++ LGP+     +QY  + G   +P  ++LG+   R+ Y + ++
Sbjct: 1179 PTPALTYRTVGGILDFYMFLGPTPEVATKQYHEVIGHPVMPAYWALGFQLCRYGYANTSE 1238

Query: 409  VLEVDQGFDDHNLPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVD 468
            V E+       N+P DV + DI++ + +  FT   +    P+  ++++  +  + + I+D
Sbjct: 1239 VRELYDAMVAANIPYDVQYTDIDYMERQLDFTIGEAFQDLPQ-FVDKIRGEGMRYIIILD 1297

Query: 469  PHIKVDSG--YRVHEELRNLGLYVKTRDGSDYEGWCWP---------------------- 504
            P I  +    Y   E  +   ++VK  + +D    CW                       
Sbjct: 1298 PAISGNETKTYPAFERGQQNDVFVKWPNTNDI---CWAKVWPDLPNITIDKTLTEDEAVN 1354

Query: 505  ---GSAGYPDFTNPTMRAWWANMFSYDNYEGSAPNLFVWNDMNEPSVF-NG--------- 551
                   +PDF   +   WWA     D Y        +W DMNEPS F NG         
Sbjct: 1355 ASRAHVAFPDFFRTSTAEWWAREI-VDFYNEKMKFDGLWIDMNEPSSFVNGTTTNQCRND 1413

Query: 552  --------PEVTMLKDAQHYG--------------GWEHRDVHNIYGLYVHMATADGLRQ 589
                    PE+T   D  H+                  H DVHN+YG      T D L++
Sbjct: 1414 ELNYPPYFPELTKRTDGLHFRTICMEAEQILSDGTSVLHYDVHNLYGWSQMKPTHDALQK 1473

Query: 590  RSGGMERPFVLARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLGLVGLSFCGADVG 649
             +G  +R  V++R+ +  S R+G  W GDN A WD++  SI   +   L G+S+ GAD+ 
Sbjct: 1474 TTG--KRGIVISRSTYPTSGRWGGHWLGDNYARWDNMDKSIIGMMEFSLFGMSYTGADIC 1531

Query: 650  GFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDIIRDALGQRYSLLP 709
            GFF N E  L  RW Q+GA+ P+ R H   +T R++P        ++ R+ L  RY+LLP
Sbjct: 1532 GFFNNSEYHLCTRWMQLGAFYPYSRNHNIANTRRQDPASWNETFAEMSRNILNIRYTLLP 1591

Query: 710  FWYTLLYQAHREGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQVYL 769
            ++YT +++ H  G  V+RPL  ++  +  T++I  Q+L G A +V PV +     V  Y+
Sbjct: 1592 YFYTQMHEIHANGGTVIRPLLHEFFDEKPTWDIFKQFLWGPAFMVTPVLEPYVQTVNAYV 1651

Query: 770  PGQGEVWYDIQSYQKHHGPQTLYLPVTLS--SIPVFQRGGTIVPRWMRVRRSSECMKDDP 827
            P     W+D  +  K  G +  +     S  +I +  RGG I+P      +++   +   
Sbjct: 1652 PNAR--WFDYHT-GKDIGVRGQFQTFNASYDTINLHVRGGHILP-CQEPAQNTFYSRQKH 1707

Query: 828  ITLFVALSPQGTAQGELFLDDGHTFNYQTRQEFLLRRFSFSGNTLVSSSADPEGHFETPI 887
            + L VA      AQG LF DDG + +   R  +L  +F+ +  TL S+        ++  
Sbjct: 1708 MKLIVAADDNQMAQGSLFWDDGESIDTYERDLYLSVQFNLNQTTLTSTILKRGYINKSET 1767

Query: 888  WIERVVIIGAG-KPAAVVLQTKGSPESRLSFQHDPETSVLVLRKPGINVASDWSIHL 943
             +  + + G G  P   V  T    ++ L F  D    +L +     NV  +  I +
Sbjct: 1768 RLGSLHVWGKGTTPVNAVTLTYNGNKNSLPFNEDTTNMILRIDLTTHNVTLEEPIEI 1824


>gi|169171979 PREDICTED: similar to sucrase-isomaltase [Homo sapiens]
          Length = 1492

 Score =  253 bits (645), Expect = 8e-67
 Identities = 191/652 (29%), Positives = 302/652 (46%), Gaps = 70/652 (10%)

Query: 349  PQTDVRWMSETGIIDVFLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEAD 408
            P   + + +  G++D ++ LGP+   V +QY  L G   + P +SLG+   R+ Y+++++
Sbjct: 834  PLPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSE 893

Query: 409  VLEVDQGFDDHNLPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVD 468
            +  +        +P DV + DI++ + +  FT  P +F     ++ R+ +   +++ I+D
Sbjct: 894  ISSLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSP-KFAGFPALINRMKADGMRVILILD 952

Query: 469  PHIKVDSGYRVHEELRNL--GLYVK-TRDGSDYEGWCWP--------GS----------- 506
            P I  +         R +   +++K   DG    G  WP        GS           
Sbjct: 953  PAISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQVELYR 1012

Query: 507  --AGYPDFTNPTMRAWWANMFS--YDNYEGSAPNLF---VWNDMNEPSVFNGPEV----- 554
                +PDF   +   WW       Y+N +    +L    +W DMNEPS F    V     
Sbjct: 1013 AYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCR 1072

Query: 555  -----------------------TMLKDAQHY----GGWEHRDVHNIYGLYVHMATADGL 587
                                   T+  ++Q         +H +VHN+YG      T + +
Sbjct: 1073 DASLNHPPYMPYLESRDRGLSSKTLCMESQQILPDGSPVQHYNVHNLYGWSQTRPTYEAV 1132

Query: 588  RQRSGGMERPFVLARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLGLVGLSFCGAD 647
            ++ +G  +R  V+ R+ F  S R+   W GDNTA WD LK SI   +   L G+S+ GAD
Sbjct: 1133 QEVTG--QRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGAD 1190

Query: 648  VGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDIIRDALGQRYSL 707
            + GFF++ E E+ VRW Q+GA+ PF R H  + T R++P        +I R  L  RY+L
Sbjct: 1191 ICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDVAFVNISRTVLQTRYTL 1250

Query: 708  LPFWYTLLYQAHREGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQV 767
            LP+ YTL+++AH EG+ V+RPL  ++  D  T++ID Q+LLG A LV PV +  A  V  
Sbjct: 1251 LPYLYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTA 1310

Query: 768  YLPGQGEVWYDIQS-YQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSECMKDD 826
            Y P     WYD  +    +   +   LP  L  I +  RGG I+P W     ++   +  
Sbjct: 1311 YFPRAR--WYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILP-WQEPALNTHLSRQK 1367

Query: 827  PITLFVALSPQGTAQGELFLDDGHTFNYQTRQEFLLRRFSFSGNTLVSSSADPEGHFET- 885
             +   +AL  +GTA G LF DDG + +   +  + L  FS S NT+ S          T 
Sbjct: 1368 FMGFKIALDDEGTAGGWLFWDDGQSIDTYGKGLYYLASFSASQNTMQSHIIFNNYITGTN 1427

Query: 886  PIWIERVVIIGAGK-PAAVVLQTKGSPESRLSFQHDPETSVLVLRKPGINVA 936
            P+ +  + I G G  P   V  +        SF +DP T VL +     N++
Sbjct: 1428 PLKLGYIEIWGVGSVPVTSVSISVSGMVITPSFNNDPTTQVLSIDVTDRNIS 1479



 Score =  234 bits (598), Expect = 2e-61
 Identities = 174/601 (28%), Positives = 285/601 (47%), Gaps = 55/601 (9%)

Query: 390 PLFSLGYHQSRWNYRDEADVLEVDQGFDDHNLPCDVIWLDIEHADGKRYFTWDPSRFPQP 449
           P +SLG+   R+ Y++++++  +        +P DV + DI++ + +  FT  P +F   
Sbjct: 3   PYWSLGFQLCRYGYQNDSEIASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSP-KFAGF 61

Query: 450 RTMLERLASKRRKLVAIVDPHIKVDSGYRVHEELRNL--GLYVK-TRDGSDYEGWCWPGS 506
             ++ R+ +   +++ I+DP I  +         R +   +++K   DG    G  +   
Sbjct: 62  PALINRMKADGMRVILILDPAISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKLYRAY 121

Query: 507 AGYPDFTNPTMRAWWANMFS--YDNYEGSAPNLF---VWNDMNEPSVF-NGPEVTMLKDA 560
             +PDF   +   WW       Y+N +    +L    +W DMNEPS F NG      +DA
Sbjct: 122 VAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCRDA 181

Query: 561 Q--------HYGGWE-----------------------HRDVHNIYGLYVHMATADGLRQ 589
                    H    +                       H +VHN+YG      T + +++
Sbjct: 182 SLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRPTYEAVQE 241

Query: 590 RSGGMERPFVLARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLGLVGLSFCGADVG 649
            +G  +R  V+ R+ F  S R+   W GDNTA WD LK SI   +      L   GAD+ 
Sbjct: 242 VTG--QRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSI---IGSFYFLLFQTGADIC 296

Query: 650 GFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDIIRDALGQRYSLLP 709
           GFF++ E E+ VRW Q+GA+ PF R H  + T R++P    +   +I R+ L  RY+LLP
Sbjct: 297 GFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDAAFVNISRNVLQTRYTLLP 356

Query: 710 FWYTLLYQAHREGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQVYL 769
           + YTL+ +AH EG+ V+RPL  ++  D  T++ID Q+LLG A LV PV +  A  V  Y 
Sbjct: 357 YLYTLMQKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTAYF 416

Query: 770 PGQGEVWYDIQS-YQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSECMKDDPI 828
           P     WYD  +    +   +   LP  L  I +  RGG I+P W     ++   + +P+
Sbjct: 417 PRAR--WYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILP-WQEPALNTHLSRKNPL 473

Query: 829 TLFVALSPQGTAQGELFLDDGHTFNYQTRQEFLLRRFSFSGNTLVSSSADPEGHFETPIW 888
            L +AL     A+GELF DDG T +   ++ +LL  FS + N L  + +         + 
Sbjct: 474 GLIIALDENKEAKGELFWDDGQTKDTVAKKVYLLCEFSVTQNHLEVTISQSTYKDPNNLA 533

Query: 889 IERVVIIGAGKPAAVVLQTKGSP-ESRLSFQHDPETSVLVLRKPGINVAS----DWSIHL 943
              + I+G  +P+ V ++  G P ++  +  +D    V ++    + +      +WSI +
Sbjct: 534 FNEIKILGMEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDINLFLGEAYTVEWSIKI 593

Query: 944 R 944
           R
Sbjct: 594 R 594


>gi|153791946 hypothetical protein LOC57462 [Homo sapiens]
          Length = 714

 Score = 77.0 bits (188), Expect = 8e-14
 Identities = 105/415 (25%), Positives = 150/415 (36%), Gaps = 49/415 (11%)

Query: 405 DEADVLEVDQGFDDHNLPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLV 464
           D+  VL   Q    H+     + +D  +      F +D  +FP    M  RL     ++ 
Sbjct: 329 DQDKVLRFAQQIRLHHFNSSHLEIDDMYTPAYGDFDFDEVKFPNASDMFRRLRDAGFRVT 388

Query: 465 AIVDPHIKVDSGYRVHEELRNLGLYVKTRDGSDYEGWCWPGSAGYPDFTNPTMRAWWANM 524
             V P +  +S        R L +   T        W W G     DFT+P  R W+   
Sbjct: 389 LWVHPFVNYNSSRFGEGVERELFVREPTGRLPALVRW-WNGIGAVLDFTHPKARDWFQGH 447

Query: 525 FSYDNYEGSAPNLFVWNDMNEPSVFNGPEVTMLKDAQHYGGWEHRDVHNIYGLYVHMATA 584
                   S  +            F+  EV+ L           RD    +  Y  +   
Sbjct: 448 LRRLRSRYSVASF----------KFDAGEVSYLP----------RD----FSTYRPLPDP 483

Query: 585 DGLRQRSGGMERPFVLARAFFAG--SQRFGAVWT-GDNTAEWDH---LKISIPMCLSLGL 638
               +R   M  PF        G  SQ     +   D  + W +   L+  IP  L++ +
Sbjct: 484 SVWSRRYTEMALPFFSLAEVRVGYQSQNISCFFRLVDRDSVWGYDLGLRSLIPAVLTVSM 543

Query: 639 VGLSFCGAD-VGGFFKN--------PEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLL 689
           +G  F   D VGG            PE EL +RW ++ A+ P  +           PW  
Sbjct: 544 LGYPFILPDMVGGNAVPQRTAGGDVPERELYIRWLEVAAFMPAMQFSI-------PPWRY 596

Query: 690 PSQHNDIIRDALGQRYSLL-PFWYTLLYQAHREGIPVMRPLWVQYPQDVTTFNIDDQYLL 748
            ++   I +     R SL+ P    L  +    G P++RPLW   P D T   ID Q+L+
Sbjct: 597 DAEVVAIAQKFAALRASLVAPLLLELAGEVTDTGDPIVRPLWWIAPGDETAHRIDSQFLI 656

Query: 749 GDALLVHPVSDSGAHGVQVYLPGQGEVWYDIQSYQKHHGPQTLYLPVTLSSIPVF 803
           GD LLV PV + G     VYLP      Y  + + K     T Y PV L  I  F
Sbjct: 657 GDTLLVAPVLEPGKQERDVYLPAGKWRSYKGELFDKTPVLLTDY-PVDLDEIAYF 710


>gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens]
          Length = 1175

 Score = 33.5 bits (75), Expect = 0.96
 Identities = 29/107 (27%), Positives = 45/107 (42%), Gaps = 23/107 (21%)

Query: 628  ISIPMCLSLGLVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPW 687
            +S+P+  SL L  +   G  +GG+F             +   QP+F     L+     P 
Sbjct: 992  LSVPVLSSLLLQMVLVTGVQLGGYF-------------LTLAQPWF---VPLNRTVAAPD 1035

Query: 688  LLPSQHNDIIRDALGQRYSLLPFWYTLLYQAHREGIPVMRPLWVQYP 734
             LP+  N ++       +SL  F Y +L  A  +G P  RPL+   P
Sbjct: 1036 NLPNYENTVV-------FSLSSFQYLILAAAVSKGAPFRRPLYTNVP 1075


>gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens]
          Length = 1180

 Score = 33.5 bits (75), Expect = 0.96
 Identities = 29/107 (27%), Positives = 45/107 (42%), Gaps = 23/107 (21%)

Query: 628  ISIPMCLSLGLVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPW 687
            +S+P+  SL L  +   G  +GG+F             +   QP+F     L+     P 
Sbjct: 997  LSVPVLSSLLLQMVLVTGVQLGGYF-------------LTLAQPWF---VPLNRTVAAPD 1040

Query: 688  LLPSQHNDIIRDALGQRYSLLPFWYTLLYQAHREGIPVMRPLWVQYP 734
             LP+  N ++       +SL  F Y +L  A  +G P  RPL+   P
Sbjct: 1041 NLPNYENTVV-------FSLSSFQYLILAAAVSKGAPFRRPLYTNVP 1080


>gi|7706589 GNAS complex locus NESP55 [Homo sapiens]
          Length = 245

 Score = 33.1 bits (74), Expect = 1.3
 Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 4/65 (6%)

Query: 182 RAPRVSQGSKDPAEGDGAQPEE-TPRDGDKPEETQGKAEKDEPGAWEETFKTHSDSKPYG 240
           RAP  +Q  + P EG+  +PE+  PRD   PEE++   E+ +    +    T  D+ P  
Sbjct: 177 RAPPSTQEPQSPREGEELKPEDKDPRD---PEESKEPKEEKQRRRCKPKKPTRRDASPES 233

Query: 241 PMSVG 245
           P   G
Sbjct: 234 PSKKG 238


>gi|157885806 chromosome 12 open reading frame 51 [Homo sapiens]
          Length = 3996

 Score = 33.1 bits (74), Expect = 1.3
 Identities = 21/69 (30%), Positives = 36/69 (52%), Gaps = 5/69 (7%)

Query: 146  PYKIILTARPFRLDLLEDRSLLLSVNARGLLEFEHQRAPRVSQGSKDPAEGDGAQPEETP 205
            P K++ T RP      +D+++L SV+   L E    + P V   S + ++ D   PE++P
Sbjct: 3341 PVKVVSTKRPITKPPAKDKAVLNSVSRTALSE----KKPTVKPKSPEKSKPDEKDPEKSP 3396

Query: 206  -RDGDKPEE 213
             +  + PEE
Sbjct: 3397 TKKQEVPEE 3405


>gi|157743252 pecanex-like 3 [Homo sapiens]
          Length = 2034

 Score = 32.7 bits (73), Expect = 1.6
 Identities = 38/157 (24%), Positives = 62/157 (39%), Gaps = 6/157 (3%)

Query: 108 PRRPRYRVPDVLVADPPIARLS-VSGRDENSVELTMAEGPYKIILTARPFRLDLLEDRSL 166
           P+ P   VPD  +A    +  S ++G        +MA+ P   +L     +   L    L
Sbjct: 197 PQTPPGAVPDPSLASTDSSEPSPLAGDGAPWSGSSMADTPMSPLLKGSLSQE--LSKSFL 254

Query: 167 LLSVNARGLLEFEHQRAPRVSQGSKDPAEGDGAQPEETPRDGDKPEETQGKAEKDEPGAW 226
            L+   R L+    +R  R   G   P +  G+  E TP+     +      +++   ++
Sbjct: 255 TLTQPDRALVRTSSRREQRRGAGGYQPLDRRGSG-EPTPQKAGSSDSCFSGTDRETLSSF 313

Query: 227 --EETFKTHSDSKPYGPMSVGLDFSLPGMEHVYGIPE 261
             E+T  TH DS P GP   G D   P    +   P+
Sbjct: 314 KSEKTNSTHLDSPPGGPAPEGSDTDPPSEAELPASPD 350


>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
           sapiens]
          Length = 521

 Score = 32.3 bits (72), Expect = 2.1
 Identities = 32/123 (26%), Positives = 49/123 (39%), Gaps = 11/123 (8%)

Query: 106 LEPRRPRYRVPDVLVADPPIARLSVSGRDENSVELTMAEGPYKIILTARPFRLDLLEDRS 165
           L P  P    P     D P +  S    D + V      GP   + T   +   + +D+ 
Sbjct: 5   LSPGSPGDPRPPTPETDYPESLTSYPEEDYSPVGSFGEPGPTSPLTTPPGWSCHVSQDKQ 64

Query: 166 LLLSVNARGLLEFEHQRAPRVSQGSKDPAEGDGAQPEETPRDGDKPEETQGKAEKDEPGA 225
           +L + +      F  ++ P  +  S   +  DG    +TP     PEE +  AE DE G+
Sbjct: 65  MLYTNH------FTQEQVPVPAPRSIHKSSQDG----DTPAQASPPEE-KVPAELDEVGS 113

Query: 226 WEE 228
           WEE
Sbjct: 114 WEE 116


>gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B
            subunit [Homo sapiens]
          Length = 2339

 Score = 32.3 bits (72), Expect = 2.1
 Identities = 25/106 (23%), Positives = 47/106 (44%), Gaps = 13/106 (12%)

Query: 184  PRVSQGSKDPAEG-----------DGAQPEETPRDGDKPEETQGKAEKDEPGAWEETFKT 232
            PR ++  ++PA             +  + E T ++  + E    +A+K++     +  + 
Sbjct: 966  PREAESGEEPARRHRARHKAQPAHEAVEKETTEKEATEKEAEIVEADKEKELRNHQPREP 1025

Query: 233  HSDSKPYGPMSVGLDFSLPG--MEHVYGIPEHADNLRLKVTEGGEP 276
            H D +  G ++VG   +LP   ++ V   PE ADN R     G +P
Sbjct: 1026 HCDLETSGTVTVGPMHTLPSTCLQKVEEQPEDADNQRNVTRMGSQP 1071


>gi|21389567 chemokine-like factor superfamily 2 [Homo sapiens]
          Length = 248

 Score = 32.0 bits (71), Expect = 2.8
 Identities = 17/43 (39%), Positives = 27/43 (62%), Gaps = 4/43 (9%)

Query: 183 APRVSQGSK-DPAEGD---GAQPEETPRDGDKPEETQGKAEKD 221
           AP+ ++G+K +PA      GA+PEE  +DG +P +   KA +D
Sbjct: 2   APKAAKGAKPEPAPAPPPPGAKPEEDKKDGKEPSDKPQKAVQD 44


>gi|83716024 kinesin family member 21B [Homo sapiens]
          Length = 1624

 Score = 32.0 bits (71), Expect = 2.8
 Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 1/58 (1%)

Query: 181 QRAPRVSQGSKDPAEGDGAQPEETPRDGDKPEETQGKAEKDEPGAWEETFKTHSDSKP 238
           ++  ++ Q + +  + + A+ EE  RD    EE +G+ ++DE    EE+    SDS P
Sbjct: 569 KKRAKLQQENSEETDENEAEEEEEERDESGCEEEEGREDEDEDSGSEESL-VDSDSDP 625


>gi|12751473 DNA cytosine methyltransferase 3 alpha isoform a [Homo
           sapiens]
          Length = 912

 Score = 31.6 bits (70), Expect = 3.6
 Identities = 15/62 (24%), Positives = 25/62 (40%)

Query: 184 PRVSQGSKDPAEGDGAQPEETPRDGDKPEETQGKAEKDEPGAWEETFKTHSDSKPYGPMS 243
           P +            A+ EE  +DG++ EE +GK E+ EP             + + P+ 
Sbjct: 2   PAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVE 61

Query: 244 VG 245
            G
Sbjct: 62  SG 63


>gi|28559071 DNA cytosine methyltransferase 3 alpha isoform c [Homo
           sapiens]
          Length = 166

 Score = 31.6 bits (70), Expect = 3.6
 Identities = 15/62 (24%), Positives = 25/62 (40%)

Query: 184 PRVSQGSKDPAEGDGAQPEETPRDGDKPEETQGKAEKDEPGAWEETFKTHSDSKPYGPMS 243
           P +            A+ EE  +DG++ EE +GK E+ EP             + + P+ 
Sbjct: 2   PAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVE 61

Query: 244 VG 245
            G
Sbjct: 62  SG 63


>gi|28559069 DNA cytosine methyltransferase 3 alpha isoform a [Homo
           sapiens]
          Length = 912

 Score = 31.6 bits (70), Expect = 3.6
 Identities = 15/62 (24%), Positives = 25/62 (40%)

Query: 184 PRVSQGSKDPAEGDGAQPEETPRDGDKPEETQGKAEKDEPGAWEETFKTHSDSKPYGPMS 243
           P +            A+ EE  +DG++ EE +GK E+ EP             + + P+ 
Sbjct: 2   PAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVE 61

Query: 244 VG 245
            G
Sbjct: 62  SG 63


>gi|50428933 C1q domain containing 1 isoform 1 [Homo sapiens]
          Length = 1127

 Score = 31.6 bits (70), Expect = 3.6
 Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 5/70 (7%)

Query: 170 VNARGLLEFEHQRAPRVSQGSKDPAEGDGAQPEETPRDGDKPEETQGKAEKDEP-GAWEE 228
           +N R + E ++       QG + P E D A+    P+  D   E  G+ +K E   +WE 
Sbjct: 370 LNRRYMTEVDYSN----KQGEEQPWEADYARKPNLPKRWDMLTEPDGQEKKQESFKSWEA 425

Query: 229 TFKTHSDSKP 238
           + K    SKP
Sbjct: 426 SGKHQEVSKP 435


>gi|50428931 C1q domain containing 1 isoform 3 [Homo sapiens]
          Length = 793

 Score = 31.6 bits (70), Expect = 3.6
 Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 5/70 (7%)

Query: 170 VNARGLLEFEHQRAPRVSQGSKDPAEGDGAQPEETPRDGDKPEETQGKAEKDEP-GAWEE 228
           +N R + E ++       QG + P E D A+    P+  D   E  G+ +K E   +WE 
Sbjct: 37  LNRRYMTEVDYSN----KQGEEQPWEADYARKPNLPKRWDMLTEPDGQEKKQESFKSWEA 92

Query: 229 TFKTHSDSKP 238
           + K    SKP
Sbjct: 93  SGKHQEVSKP 102


>gi|23503235 C1q domain containing 1 isoform 2 [Homo sapiens]
          Length = 1077

 Score = 31.6 bits (70), Expect = 3.6
 Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 5/70 (7%)

Query: 170 VNARGLLEFEHQRAPRVSQGSKDPAEGDGAQPEETPRDGDKPEETQGKAEKDEP-GAWEE 228
           +N R + E ++       QG + P E D A+    P+  D   E  G+ +K E   +WE 
Sbjct: 370 LNRRYMTEVDYSN----KQGEEQPWEADYARKPNLPKRWDMLTEPDGQEKKQESFKSWEA 425

Query: 229 TFKTHSDSKP 238
           + K    SKP
Sbjct: 426 SGKHQEVSKP 435


>gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens]
          Length = 1158

 Score = 31.2 bits (69), Expect = 4.8
 Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 23/103 (22%)

Query: 628  ISIPMCLSLGLVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPW 687
            +S+P+  SL L  +   G  +GG+F             +   QP+F     L+     P 
Sbjct: 953  LSVPVLSSLLLQMVLVTGVQLGGYF-------------LTLAQPWF---VPLNRTVAAPD 996

Query: 688  LLPSQHNDIIRDALGQRYSLLPFWYTLLYQAHREGIPVMRPLW 730
             LP+  N ++       +SL  F Y +L  A  +G P  RPL+
Sbjct: 997  NLPNYENTVV-------FSLSSFQYLILAAAVSKGAPFRRPLY 1032


>gi|47106061 KRAB-A domain containing 2 [Homo sapiens]
          Length = 492

 Score = 31.2 bits (69), Expect = 4.8
 Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 3/82 (3%)

Query: 710 FWYTLLYQAHREGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQVYL 769
           F + L YQ H     ++RPL  +   +V +  +D   +LG   ++   SDSG       +
Sbjct: 278 FKFILYYQDHSTKFIILRPLRTKQAHEVVSVLLDIFTILGTPSVLD--SDSGVEFTNQVV 335

Query: 770 PGQGEVWYDIQSYQ-KHHGPQT 790
               E+W D++    K+H  Q+
Sbjct: 336 HELNELWPDLKIVSGKYHPGQS 357


>gi|126723149 chromosome 19 open reading frame 29 [Homo sapiens]
          Length = 758

 Score = 30.8 bits (68), Expect = 6.2
 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 2/82 (2%)

Query: 187 SQGSKDPAEGDGAQPEETPRDGDKPEETQGKAEKDEPGAWEETFKTHSDSKPYGPMSVGL 246
           S+G    AE DGA P E   DGD   E +G+A   E    +++   + D+  Y P  +  
Sbjct: 508 SEGGPAEAEVDGATPTEGDGDGDGEGEGEGEAVLMEEDLIQQSLDDY-DAGRYSPRLL-T 565

Query: 247 DFSLPGMEHVYGIPEHADNLRL 268
              LP   HV    E    L+L
Sbjct: 566 AHELPLDAHVLEPDEDLQRLQL 587


>gi|122937392 chromosome 19 open reading frame 29 [Homo sapiens]
          Length = 758

 Score = 30.8 bits (68), Expect = 6.2
 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 2/82 (2%)

Query: 187 SQGSKDPAEGDGAQPEETPRDGDKPEETQGKAEKDEPGAWEETFKTHSDSKPYGPMSVGL 246
           S+G    AE DGA P E   DGD   E +G+A   E    +++   + D+  Y P  +  
Sbjct: 508 SEGGPAEAEVDGATPTEGDGDGDGEGEGEGEAVLMEEDLIQQSLDDY-DAGRYSPRLL-T 565

Query: 247 DFSLPGMEHVYGIPEHADNLRL 268
              LP   HV    E    L+L
Sbjct: 566 AHELPLDAHVLEPDEDLQRLQL 587


>gi|239756047 PREDICTED: heparan sulfate 6-O-sulfotransferase 3
           [Homo sapiens]
          Length = 471

 Score = 30.4 bits (67), Expect = 8.1
 Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 2/47 (4%)

Query: 179 EHQRAPRVSQGSKDPAEGD--GAQPEETPRDGDKPEETQGKAEKDEP 223
           E +R P++    + P EG    A PEE   +   P E + + E+DEP
Sbjct: 64  EWERRPQLPPPPRGPPEGPRGAAAPEEEDEEPGDPREGEEEEEEDEP 110


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.138    0.436 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,141,766
Number of Sequences: 37866
Number of extensions: 1970060
Number of successful extensions: 4735
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 4637
Number of HSP's gapped (non-prelim): 64
length of query: 944
length of database: 18,247,518
effective HSP length: 112
effective length of query: 832
effective length of database: 14,006,526
effective search space: 11653429632
effective search space used: 11653429632
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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