Search of human proteins with 38044290

Search of human proteins with 38044290

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38044290 zinc finger, CCHC domain containing 8 [Homo
sapiens]
         (707 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38044290 zinc finger, CCHC domain containing 8 [Homo sapiens]     1438   0.0  
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    49   2e-05
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    46   1e-04
gi|167736355 mucin 4 isoform a [Homo sapiens]                          46   1e-04
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    45   2e-04
gi|24431935 reticulon 4 isoform A [Homo sapiens]                       45   3e-04
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    44   4e-04
gi|29294655 melanoma antigen family C, 3 isoform 2 [Homo sapiens]      44   4e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni...    44   4e-04
gi|47519490 reticulon 4 isoform D [Homo sapiens]                       44   7e-04
gi|195963410 MEF2 activating motif and SAP domain containing tra...    44   7e-04
gi|32698970 MEF2 activating motif and SAP domain containing tran...    44   7e-04
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2...    44   7e-04
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1...    44   7e-04
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           44   7e-04
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           44   7e-04
gi|5730045 solute carrier family 16, member 2 [Homo sapiens]           43   9e-04
gi|56549694 enabled homolog isoform a [Homo sapiens]                   42   0.001
gi|39930375 enabled homolog isoform b [Homo sapiens]                   42   0.001
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    42   0.001
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    42   0.001
gi|118498345 AT-binding transcription factor 1 [Homo sapiens]          42   0.001
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap...    42   0.001
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap...    42   0.001
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    42   0.002
gi|20162568 melanoma antigen family C, 3 isoform 1 [Homo sapiens]      42   0.002
gi|150170670 piccolo isoform 2 [Homo sapiens]                          42   0.002
gi|150378539 piccolo isoform 1 [Homo sapiens]                          42   0.002
gi|149999615 variable charge, X-linked 3B [Homo sapiens]               42   0.002
gi|239753435 PREDICTED: hypothetical protein XP_002345651 [Homo ...    42   0.003

>gi|38044290 zinc finger, CCHC domain containing 8 [Homo sapiens]
          Length = 707

 Score = 1438 bits (3723), Expect = 0.0
 Identities = 707/707 (100%), Positives = 707/707 (100%)

Query: 1   MAAEVYFGDLELFEPFDHPEESIPKPVHTRFKDDDGDEEDENGVGDAELRERLRQCEETI 60
           MAAEVYFGDLELFEPFDHPEESIPKPVHTRFKDDDGDEEDENGVGDAELRERLRQCEETI
Sbjct: 1   MAAEVYFGDLELFEPFDHPEESIPKPVHTRFKDDDGDEEDENGVGDAELRERLRQCEETI 60

Query: 61  EQLRAENQELKRKLNILTRPSGILVNDTKLDGPILQILFMNNAISKQYHQEIEEFVSNLV 120
           EQLRAENQELKRKLNILTRPSGILVNDTKLDGPILQILFMNNAISKQYHQEIEEFVSNLV
Sbjct: 61  EQLRAENQELKRKLNILTRPSGILVNDTKLDGPILQILFMNNAISKQYHQEIEEFVSNLV 120

Query: 121 KRFEEQQKNDVEKTSFNLLPQPSSIVLEEDHKVEESCAIKNNKEAFSVVGSVLYFTNFCL 180
           KRFEEQQKNDVEKTSFNLLPQPSSIVLEEDHKVEESCAIKNNKEAFSVVGSVLYFTNFCL
Sbjct: 121 KRFEEQQKNDVEKTSFNLLPQPSSIVLEEDHKVEESCAIKNNKEAFSVVGSVLYFTNFCL 180

Query: 181 DKLGQPLLNENPQLSEGWEIPKYHQVFSHIVSLEGQEIQVKAKRPKPHCFNCGSEEHQMK 240
           DKLGQPLLNENPQLSEGWEIPKYHQVFSHIVSLEGQEIQVKAKRPKPHCFNCGSEEHQMK
Sbjct: 181 DKLGQPLLNENPQLSEGWEIPKYHQVFSHIVSLEGQEIQVKAKRPKPHCFNCGSEEHQMK 240

Query: 241 DCPMPRNAARISEKRKEYMDACGEANNQNFQQRYHAEEVEERFGRFKPGVISEELQDALG 300
           DCPMPRNAARISEKRKEYMDACGEANNQNFQQRYHAEEVEERFGRFKPGVISEELQDALG
Sbjct: 241 DCPMPRNAARISEKRKEYMDACGEANNQNFQQRYHAEEVEERFGRFKPGVISEELQDALG 300

Query: 301 VTDKSLPPFIYRMRQLGYPPGWLKEAELENSGLALYDGKDGTDGETEVGEIQQNKSVTYD 360
           VTDKSLPPFIYRMRQLGYPPGWLKEAELENSGLALYDGKDGTDGETEVGEIQQNKSVTYD
Sbjct: 301 VTDKSLPPFIYRMRQLGYPPGWLKEAELENSGLALYDGKDGTDGETEVGEIQQNKSVTYD 360

Query: 361 LSKLVNYPGFNISTPRGIPDEWRIFGSIPMQACQQKDVFANYLTSNFQAPGVKSGNKRSS 420
           LSKLVNYPGFNISTPRGIPDEWRIFGSIPMQACQQKDVFANYLTSNFQAPGVKSGNKRSS
Sbjct: 361 LSKLVNYPGFNISTPRGIPDEWRIFGSIPMQACQQKDVFANYLTSNFQAPGVKSGNKRSS 420

Query: 421 SHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLPPDTPPLPRGTP 480
           SHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLPPDTPPLPRGTP
Sbjct: 421 SHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLPPDTPPLPRGTP 480

Query: 481 PPVFTPPLPKGTPPLTPSDSPQTRTASGAVDEDALTLEELEEQQRRIWAALEQAESVNSD 540
           PPVFTPPLPKGTPPLTPSDSPQTRTASGAVDEDALTLEELEEQQRRIWAALEQAESVNSD
Sbjct: 481 PPVFTPPLPKGTPPLTPSDSPQTRTASGAVDEDALTLEELEEQQRRIWAALEQAESVNSD 540

Query: 541 SDVPVDTPLTGNSVASSPCPNELDLPVPEGKTSEKQTLDEPEVPEIFTKKSEAGHASSPD 600
           SDVPVDTPLTGNSVASSPCPNELDLPVPEGKTSEKQTLDEPEVPEIFTKKSEAGHASSPD
Sbjct: 541 SDVPVDTPLTGNSVASSPCPNELDLPVPEGKTSEKQTLDEPEVPEIFTKKSEAGHASSPD 600

Query: 601 SEVTSLCQKEKAELAPVNTEGALLDNGSVVPNCDISNGGSQKLFPADTSPSTATKIHSPI 660
           SEVTSLCQKEKAELAPVNTEGALLDNGSVVPNCDISNGGSQKLFPADTSPSTATKIHSPI
Sbjct: 601 SEVTSLCQKEKAELAPVNTEGALLDNGSVVPNCDISNGGSQKLFPADTSPSTATKIHSPI 660

Query: 661 PDMSKFATGITPFEFENMAESTGMYLRIRSLLKNSPRNQQKNKKASE 707
           PDMSKFATGITPFEFENMAESTGMYLRIRSLLKNSPRNQQKNKKASE
Sbjct: 661 PDMSKFATGITPFEFENMAESTGMYLRIRSLLKNSPRNQQKNKKASE 707


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 36/112 (32%), Positives = 49/112 (43%), Gaps = 13/112 (11%)

Query: 404 TSNFQAPGVKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQ 463
           T + QAP   + +   +  S P SP  Q   S  A  P         + P  S ++   Q
Sbjct: 647 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP-SLAAPPLQ 705

Query: 464 FQPPLPPDTPPL-PRGTPPPVFTPPL----------PKGTPPLTPSDSPQTR 504
             PP PP +PP+ P  TPPP   PPL          P  +PP++PS +P  R
Sbjct: 706 V-PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPR 756



 Score = 37.0 bits (84), Expect = 0.063
 Identities = 20/47 (42%), Positives = 25/47 (53%), Gaps = 6/47 (12%)

Query: 466 PPLPPDTPPLPRGTP----PPVFTPPLPKGTPPLTP--SDSPQTRTA 506
           PPL P   P P+  P    PP+  PP P  +PPL+P  + SPQ   A
Sbjct: 609 PPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNA 655



 Score = 37.0 bits (84), Expect = 0.063
 Identities = 30/105 (28%), Positives = 45/105 (42%), Gaps = 13/105 (12%)

Query: 408 QAPGVKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPP 467
           QAP   +     +  S P SP      + S  +P  + +   ++ P     S   Q  P 
Sbjct: 620 QAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL-LQAPFSPPPSPPVQ-APF 677

Query: 468 LPPDTPPL-PRGTPP----------PVFTPPLPKGTPPLTPSDSP 501
            PP +PP+ P  TPP          P+  PP P  +PP++PS +P
Sbjct: 678 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 722



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 49/192 (25%), Positives = 73/192 (38%), Gaps = 30/192 (15%)

Query: 419 SSSHSSPGSPKKQKN--ESNSAGSPADMELDSDMEV-PHGSQSSESFQFQPP-LPPDTPP 474
           S S  +P SP    +   + S GSP      S + + P  +Q+S +   +P   PPD+PP
Sbjct: 397 SPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPP 456

Query: 475 LPRGTPPPVFTPPLPKGTPPLTPSDSPQT----------RTASGAVDEDALTLEELEEQQ 524
           L      P   P     +P ++P  SP T           + S      +L +  LE Q 
Sbjct: 457 LQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQS 516

Query: 525 RRIWAALE---------QAESVNSDSDVPVDT---PLTGNSVASSPCPNELDLPVPEGKT 572
                +L+           E++ S +  P+ T   PLT   + + PCP    L  P    
Sbjct: 517 SLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPL 576

Query: 573 SEKQTLDEPEVP 584
               T   PE P
Sbjct: 577 ----TTPPPETP 584



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 4/45 (8%)

Query: 466 PPLPPDTPPL-PRGTPPPVFTPPL---PKGTPPLTPSDSPQTRTA 506
           PP PP +PP+ P  TPPP   P L   P   PP  P+  P +  A
Sbjct: 738 PPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLA 782



 Score = 34.7 bits (78), Expect = 0.31
 Identities = 26/98 (26%), Positives = 39/98 (39%), Gaps = 11/98 (11%)

Query: 408 QAPGVKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPP 467
           QAP   +        S P SP    + +    +P  +     ++VP    +S      PP
Sbjct: 694 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP-LQVPPSPPAS------PP 746

Query: 468 LPPDTPPLPRGTP----PPVFTPPLPKGTPPLTPSDSP 501
           + P   P PR  P    PP+  PP P  + P++P   P
Sbjct: 747 MSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP 784



 Score = 31.2 bits (69), Expect = 3.5
 Identities = 33/137 (24%), Positives = 44/137 (32%), Gaps = 13/137 (9%)

Query: 386 GSIPMQACQQKDVFANYLTSNFQAPGVKSGNKRSSSHSSPGSPK-------KQKNESNSA 438
           G +   A +     A  L+S  ++     G  R+ +H S   PK        Q       
Sbjct: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD 291

Query: 439 GSPADMELDSDMEVPHGSQSSESFQFQPP------LPPDTPPLPRGTPPPVFTPPLPKGT 492
            +PA   L S          +++    PP      LP   PP P    P    PP P   
Sbjct: 292 AAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAP 351

Query: 493 PPLTPSDSPQTRTASGA 509
           P L    SP     S A
Sbjct: 352 PSLQTLPSPPATPPSQA 368


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
           sapiens]
          Length = 2524

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 59/267 (22%), Positives = 93/267 (34%), Gaps = 39/267 (14%)

Query: 410 PGVKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLP 469
           P   + +  + S  SP +   +    N    PA +  D     P G  +        P  
Sbjct: 739 PATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGP---PPGPPTPPPEDIPAPTE 795

Query: 470 PDTPPLPRGTPPPVFTPPLPKGTPPLTPSDSPQTRTASGAVDEDALTLEELEEQQRRIWA 529
           P       G P P   PP P   PP+ P +  +  TA+      A  +EE EEQ+     
Sbjct: 796 PTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAA------APPVEEGEEQKP---P 846

Query: 530 ALEQAESVNSDSDVPVDTPLTGNSVASSPCPNELDLPVPEGKTSEKQTLDEPEVPEIFTK 589
           A E+       ++ PV           S C  E +    +GK +E          +   K
Sbjct: 847 AAEELAVDTGKAEEPV----------KSECTEEAEEGPAKGKDAEAAEATAEGALKAEKK 896

Query: 590 KSEAGHASS-------PDSEVTSLCQKEKAELAPVNTEGALLD--NGSVVPNCD-ISNGG 639
           +  +G A++        DS+ ++ C  ++ + A    +  LL      + P  D  +N  
Sbjct: 897 EGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANAS 956

Query: 640 SQKLFP-------ADTSPSTATKIHSP 659
            QK          A   P   TK+H P
Sbjct: 957 PQKPLDLKQLKQRAAAIPPIVTKVHEP 983


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 63/275 (22%), Positives = 104/275 (37%), Gaps = 29/275 (10%)

Query: 418  RSSSHSSPGSPKKQKNESNSAGSPADMELDSDME----VPHGSQSSESFQFQPPLPPDTP 473
            R +  SSP SP     E+ +    A  +          +   SQ++++F   PP PP   
Sbjct: 884  RPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSIT 943

Query: 474  PLPRGTPPPVFTPPLPKGTPPLTPSDSPQTRTASGAVDEDALTLEELEEQQRRIWAALE- 532
                 +P           T  L+PS S +T T +   +   L +             L  
Sbjct: 944  STGLTSP--------QTETHTLSPSGSGKTFTTALISNATPLPVTYASSASTGHTTPLHV 995

Query: 533  -QAESVNSD--SDVPVDTPLTGNSVASSPCP--------NELDLPVPEGKTSEKQTLDEP 581
              A SV++   + +PV +P + ++  ++P P             P+P    S   T D  
Sbjct: 996  TDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGDST 1055

Query: 582  EVPEIFTKKSEAGHASS-PDSEVTSLCQKEKAELAPVNTEGALLDNGSVVPNCD---ISN 637
             +P   T  +  GH +  P + ++S    +   L   +T  A   + + +P  D   +S 
Sbjct: 1056 PLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHATSLPVTDTSSVST 1115

Query: 638  GGSQKLFPADT-SPSTATKIHSPIPDMSKFATGIT 671
            G +  L   DT S ST      P+ D S  +TG T
Sbjct: 1116 GHTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHT 1150



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 7/128 (5%)

Query: 547  TPLTGNSVASSPCPNELDLPVPEGKTSEKQTLDEPEVPEIFTKKSEAGHASS-PDSEVTS 605
            TPL   S++S    +   LPV +  TS   T     +P   T  +  GHA+  PD++ +S
Sbjct: 2799 TPLPVTSLSSVSTGDTTPLPVTD--TSSASTGHATSLPVTDTSSASTGHATPLPDTDTSS 2856

Query: 606  LCQKEKAELAPVNTEGALLDNGSVVPNCDISNGGSQKLFPAD-TSPSTATKIHS---PIP 661
                    L   +T  A + + + +P  D S+  +    P   TSPS+A+  H+   P+ 
Sbjct: 2857 ASTGHATLLPVTDTSSASIGHATSLPVTDTSSISTGHATPLHVTSPSSASTGHATPLPVT 2916

Query: 662  DMSKFATG 669
            D S  +TG
Sbjct: 2917 DTSSASTG 2924



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 77/318 (24%), Positives = 115/318 (36%), Gaps = 50/318 (15%)

Query: 412  VKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDSDME------VPHGSQSSESFQFQ 465
            V S +  S+ H++P       + S    +P  +   S         +P    SS S    
Sbjct: 3619 VTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSASTGQA 3678

Query: 466  PPLPP---------DTPPLP----------RGTPPPVFTP---------PLPKGTPPLTP 497
             PLP          DT PLP            TP PV  P         PLP  +P    
Sbjct: 3679 TPLPVTSLSSVSTGDTTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSAS 3738

Query: 498  SDS----PQTRTASGAV-DEDALTLEELEEQQRRIWAALEQAESVNSDSDVPVDTPLTGN 552
            +      P T  +S +  D   L + +      R    L   ++ ++ +D     P+T  
Sbjct: 3739 TGHATPLPVTGLSSASTGDTTPLPVTDTSSASTRHATPLPVTDTSSASTDDTTRLPVTDV 3798

Query: 553  SVASSPCPNELDLPVPEGKTSEKQTLDEPEVPEIFTKKSEAGHASS-PDSEVTSLCQKEK 611
            S AS+        P+P   TS   T D   +P   T     GHA+S P +  +S      
Sbjct: 3799 SSASTGHAT----PLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHA 3854

Query: 612  AELAPVNTEGALLDNGSVVPNCDISNGGSQKLFPAD-TSPSTATKIHS---PIPDMSKFA 667
              L   +T      + + +P    S+  +    P   TSPS+A+  H+   P+   S  +
Sbjct: 3855 TPLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSAS 3914

Query: 668  TG-ITPFEFENMAE-STG 683
            TG  TP    N +  STG
Sbjct: 3915 TGDTTPLPVTNASSLSTG 3932



 Score = 38.5 bits (88), Expect = 0.022
 Identities = 63/289 (21%), Positives = 100/289 (34%), Gaps = 34/289 (11%)

Query: 412  VKSGNKRSSSHSSPGSPKKQKNESNSAGSP------ADMELDSDMEVPHGSQSSESFQFQ 465
            V S +  S+ H++P       + S    +P      +    D    +P    SS S    
Sbjct: 1651 VTSPSSASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSASTGQA 1710

Query: 466  PPLPP---------DTPPLPRGTP---------PPVFTPPLPKGTPPLTPSDSPQTRTAS 507
             PLP          DT PLP  +P         P + T      T   TP     T + S
Sbjct: 1711 TPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDTSSVS 1770

Query: 508  GAVDEDALTLEELEEQQRRIWAALEQAESVNSDSDVPVDTPLTGNSVASSPCPNELDLPV 567
             A     L +  L          L   +  ++ +   +  P+T  S AS+        P+
Sbjct: 1771 TA-HATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTT----PL 1825

Query: 568  PEGKTSEKQTLDEPEVPEIFTKKSEAGHASS-PDSEVTSLCQKEKAELAPVNTEGALLDN 626
            P    S   T D   +P      + +GH +S P ++ +S+       L   +       +
Sbjct: 1826 PVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVSTGD 1885

Query: 627  GSVVPNCD---ISNGGSQKLFPAD-TSPSTATKIHSPIPDMSKFATGIT 671
             + +P  D    S G +  L   D +S ST      P+  +S  +TG T
Sbjct: 1886 TTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDT 1934



 Score = 38.1 bits (87), Expect = 0.028
 Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 7/125 (5%)

Query: 566  PVPEGKTSEKQTLDEPEVPEIFTKKSEAGHASS-PDSEVTSLCQKEKAELAPVNTEGALL 624
            P+P    S   T D   +P   T     GHA+S P ++ +S        L   +T  A  
Sbjct: 2128 PLPVTSPSSASTGDTTPLPVTDTSSVSTGHATSLPVTDTSSASTGHATSLPVTDTSSAST 2187

Query: 625  DNGSVVPNCDISNGGSQKLFPAD-TSPSTATKIHS---PIPDMSKFATG-ITPFEFENMA 679
             + + +P  D S+  + +  P   TSPS+A+  H+    + D S  +TG  TP    +++
Sbjct: 2188 GHATPLPVTDTSSASTGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLS 2247

Query: 680  E-STG 683
              STG
Sbjct: 2248 SASTG 2252



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 61/248 (24%), Positives = 88/248 (35%), Gaps = 42/248 (16%)

Query: 452  VPHGSQSSESFQFQPPLP-PDTPPLPRGTPPPVFTPPLPKGTPPLTPSDSPQTRTA---- 506
            +P  S SS S     PLP  DTP    G   P+          P+T + S  TR A    
Sbjct: 2497 LPVTSPSSASTGHTTPLPVTDTPSASTGDTTPL----------PVTNASSLSTRHATSLH 2546

Query: 507  ----SGAVDEDALTLEELEEQQRRIWAALEQAESVNSDSDVPVDTPLTGNSVASSPCPNE 562
                S A    A +L   +        A     +  S +     TPL      S+     
Sbjct: 2547 VTSPSSASTGHATSLPVTDTSAASTGHATPLPVTSTSSASTGDTTPLPVTDTYSASTGQA 2606

Query: 563  LDLPVPEGKTSEKQTLDEPEVPEIFTKKSEAGHASS-PDSEVTSLCQKEKAELAPVNTEG 621
              LPV +  TS   T D   +P   T  +  GHA+  P +  +S+       L   +   
Sbjct: 2607 TPLPVTD--TSSASTGDTTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATPLHVTSPSS 2664

Query: 622  ALLDNGSVVPNCD---ISNGGSQKLFPADTS--------------PSTATKIHS---PIP 661
            A   + + +P  D   +S G +  L   D S              PS+A+  H+   P+ 
Sbjct: 2665 ASTGHTTPLPVTDASSVSTGHATSLPVTDASSVFTGHATSLPVTIPSSASSGHTTPLPVT 2724

Query: 662  DMSKFATG 669
            D S  +TG
Sbjct: 2725 DASSVSTG 2732



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 67/303 (22%), Positives = 111/303 (36%), Gaps = 50/303 (16%)

Query: 412  VKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQ------SSESFQFQ 465
            V S +  S+ H++P       + S    +P  +   S     H +       SS S    
Sbjct: 2899 VTSPSSASTGHATPLPVTDTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHA 2958

Query: 466  PPLPP---------DTPPLPRGTPPPVFTPPLPKGTPPLTPSDS-----------PQTRT 505
             PLP          DT PLP  +P    T      T PL  +D+           P T T
Sbjct: 2959 TPLPVTSLSSVSTGDTTPLPVTSPSSASTGH----TTPLPVTDTSSASTGQATALPVTST 3014

Query: 506  ASGAV-DEDALTLEELEE----QQRRIWAALEQAESVNSDSDVPVDTPLTGNSVASSP-- 558
            +S +  D   L + +       Q   +      + S    + +PV +P + ++  ++P  
Sbjct: 3015 SSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLL 3074

Query: 559  ------CPNELDLPVPEGKTSEKQTLDEPEVPEIFTKKSEAGHASS-PDSEVTSLCQKEK 611
                         P+P    S   T D   +P      +  GHA+S P ++ +S    + 
Sbjct: 3075 VTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDT 3134

Query: 612  AELAPVNTEGALLDNGSVVPNCDISN---GGSQKLFPADTSPSTATKIHSP--IPDMSKF 666
              L   +T  A   + + +P  D S+   G +  L   +TS S +T   +P  + D S  
Sbjct: 3135 TSLPVTDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLVTETS-SVSTGHATPLLVTDASSA 3193

Query: 667  ATG 669
            +TG
Sbjct: 3194 STG 3196



 Score = 35.4 bits (80), Expect = 0.18
 Identities = 37/143 (25%), Positives = 59/143 (41%), Gaps = 11/143 (7%)

Query: 534  AESVNSDSDVPVDTPLTGNSVASSPCPNELDLPVPEGKTSEKQTLDEPEVPEIFTKKSEA 593
            A SV++    P+  P+T +S ASS        P+P    S   T D   +P   T  +  
Sbjct: 2358 ASSVSTGDTTPL--PVTSSSSASSGHTT----PLPVTDASSASTGDTTPLPVTDTSSAST 2411

Query: 594  GHASS-PDSEVTSLCQKEKAELAPVNTEGALLDNGSVVPNCDISNG--GSQKLFPADTSP 650
            GHA+  P + ++S    +   L   N   A   + + +P    S+   G     P   + 
Sbjct: 2412 GHATHLPVTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSASTGDTTPLPGTDTS 2471

Query: 651  STATKIHSP--IPDMSKFATGIT 671
            S +T   +P  + D S  +TG T
Sbjct: 2472 SVSTGHTTPLLVTDASSVSTGDT 2494



 Score = 34.7 bits (78), Expect = 0.31
 Identities = 44/155 (28%), Positives = 63/155 (40%), Gaps = 23/155 (14%)

Query: 536  SVNSDSDVPVDTPLTGNSVASSPCPNELDL------------PVPEGKTSEKQTLDEPEV 583
            SV++    P+  P+TG S AS+     L +            P+P   TS   T D   +
Sbjct: 3224 SVSTGHATPL--PVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDTMPL 3281

Query: 584  PEIFTKKSEAGHASSPDSEVTSLCQKEKAELAPV-NTEGALLDNGSVVPNCDISNGGSQK 642
            P      +  GHA+      TS      A   PV +T  A   + + +P  D S+  +  
Sbjct: 3282 PVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSSASTGD 3341

Query: 643  LFPAD-TSPSTA-----TKIHSPIPDMSKFATGIT 671
              P   TSPS+A     T +H  IP  S  +TG T
Sbjct: 3342 TTPLPVTSPSSASTGHTTPLHVTIP--SSASTGDT 3374



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 59/240 (24%), Positives = 82/240 (34%), Gaps = 28/240 (11%)

Query: 447  DSDMEVPHGSQSSESFQFQPPLPP---------DTPPLPRGTPPPVFTPPLPKGTPPLTP 497
            D    +P    SS S     PLP          DT PLP      V T      + P+T 
Sbjct: 3788 DDTTRLPVTDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHAT--SLPVTS 3845

Query: 498  SDSPQTRTASGAVDEDALTLEELEEQQRRIWAALEQAESVNSDSDVPVDTPLTGNSVASS 557
              S  T  A+     D  ++         + +      SV++    P+  P+T  S AS+
Sbjct: 3846 RSSASTGHATPLPVTDTSSVSTGHATPLPVTST----SSVSTGHATPL--PVTSPSSAST 3899

Query: 558  PCPNELDLPVPEGKTSEKQTLDEPEVPEIFTKKSEAGHASSPDSEVTSLCQKEKAELAPV 617
                    PVP   TS   T D   +P         GHA+       S   +      PV
Sbjct: 3900 GHAT----PVPVTSTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASRGDTSTLPV 3955

Query: 618  NTEGALLDNGSVVP-----NCDISNGGSQKLFPADT-SPSTATKIHSPIPDMSKFATGIT 671
             T+ +    G   P        +S G +  L   DT S ST      P+  +S  +TG T
Sbjct: 3956 -TDASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDT 4014



 Score = 31.6 bits (70), Expect = 2.6
 Identities = 33/141 (23%), Positives = 55/141 (39%), Gaps = 13/141 (9%)

Query: 536  SVNSDSDVPVDTPLTGNSVASSPCPNELDLPVPEGKTSEKQTLDEPEVPEIFTKKSEAGH 595
            S    + +PV +P + +S  ++P P      VP G  +     D   V          GH
Sbjct: 1930 STGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVTDASSV--------STGH 1981

Query: 596  ASS-PDSEVTSLCQKEKAELAPVNTEGALLDNGSVVPNCDISN---GGSQKLFPADT-SP 650
            A+  P ++ +S+       L   +T        + +P   +S+   G +  L   DT S 
Sbjct: 1982 ATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSASTGDTTPLPVTDTSSA 2041

Query: 651  STATKIHSPIPDMSKFATGIT 671
            ST      P+  +S  +TG T
Sbjct: 2042 STGQDTPLPVTSLSSVSTGDT 2062



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 62/268 (23%), Positives = 86/268 (32%), Gaps = 49/268 (18%)

Query: 440  SPADMELDSDMEVPHGSQSSESFQFQPPLP---------PDTPPLPRGTPPPVFTPPLPK 490
            SP+         +P    SS S     PLP          DT PLP        T    +
Sbjct: 3941 SPSSASRGDTSTLPVTDASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTG---Q 3997

Query: 491  GTP-PLTPSDSPQTRTASGAVDEDALTLEELEEQQRRIWAALEQAESVNSDSDVPVDTPL 549
             TP P+T   S  T    G      +T+             +  A SV++    P+  P+
Sbjct: 3998 ATPLPVTSLSSVST----GDTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTPL--PV 4051

Query: 550  TGNSVASSPCPNELDLPVPEGKTSEKQTLDEPEVPEIFTKKSEAGHASSPDSEVTSLCQK 609
            T  S AS+        P+P   TS   T     +P   T  +  GHA+     VTSL   
Sbjct: 4052 TSTSSASTGDTT----PLPVTDTSSASTGHATPLPVTDTSSASTGHAT--PLPVTSLSSV 4105

Query: 610  EKAELAPVNTEGA-------------LLDNGSVVPNCDISNGGSQKLFPADTS------- 649
                  P+    A             +   G   P+     G      P  T+       
Sbjct: 4106 STGHATPLAVSSATSASTVSSDSPLKMETPGMTTPSLKTDGGRRTATSPPPTTSQTIIST 4165

Query: 650  -PSTATKIHS---PIPDMSKFATGITPF 673
             PSTA    S   PIP + +    + P+
Sbjct: 4166 IPSTAMHTRSTAAPIPILPERGVSLFPY 4193


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 52/184 (28%), Positives = 72/184 (39%), Gaps = 23/184 (12%)

Query: 323 LKEAELENSGLALYDGKDGTDGETEVGEIQQNKSVTYDLSKLVNYPGFNISTPRGI---P 379
           L+ A+ +     L D + GT    +V +I    +   + SK  N  G   +  RG    P
Sbjct: 38  LRRADPKGRSALLADIQQGTRLR-KVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPP 96

Query: 380 DEWRIF-GSIP-MQACQQKDVFANYLTSNFQAPGVKSGNKRSSSHSSPGSPKKQKNESNS 437
               +F G  P ++   Q+DV            G K+G    S   SP  P K    S  
Sbjct: 97  TLGDLFAGGFPVLRPAGQRDV-----------AGGKTGQGPGSRAPSPRLPNK--TISGP 143

Query: 438 AGSPADMELDSDMEVPHGSQSSESFQFQPPLPPDTPPLPRGTPPPVFTPPLPKGTPPLTP 497
              PA   L +  E    ++++      P  PP TPP     PPP   PPLP  +P  TP
Sbjct: 144 LIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPP----PPPPPLPPPLPSSSPIKTP 199

Query: 498 SDSP 501
             SP
Sbjct: 200 LVSP 203



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 1/82 (1%)

Query: 466 PPLPPDTPPLPRGTPPPVFTPPLPKGTPPLTPSDSPQTRTASGAVDEDALTLEELEEQQR 525
           PPLPP  PPL    PPP   PP+   T  L  +D P+ R+A  A  +    L ++ +   
Sbjct: 9   PPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRAD-PKGRSALLADIQQGTRLRKVTQIND 67

Query: 526 RIWAALEQAESVNSDSDVPVDT 547
           R    +E ++  N +     +T
Sbjct: 68  RSAPQIESSKGTNKEGGGSANT 89



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 48/191 (25%), Positives = 62/191 (32%), Gaps = 28/191 (14%)

Query: 466 PPLPPDTPPLPRGTPP--------------PVFTPPLPKGTPPLTPSDSPQTRTASGAVD 511
           PP PP  PP P   PP              P+  PP+P   P L P   P  +    +  
Sbjct: 224 PPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPA 283

Query: 512 EDAL-------TLEELEEQQRRIWAALEQAESVNSDSDVPVDTPLTGNSVASSPCPNELD 564
           +DA         L        R          VNS S+ P   P    S  + P      
Sbjct: 284 QDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQ 343

Query: 565 L----PVPEGKTS--EKQTLDEPEVPEIFTKKSEAGHASSPDSEVTSLCQKEKAELAPVN 618
                P P G     +K+    P           A  A SP +E++S  Q+  A   P  
Sbjct: 344 ALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATA-WTPTQ 402

Query: 619 TEGALLDNGSV 629
             G  L NGS+
Sbjct: 403 QPGGQLRNGSL 413



 Score = 34.3 bits (77), Expect = 0.41
 Identities = 14/37 (37%), Positives = 20/37 (54%)

Query: 474 PLPRGTPPPVFTPPLPKGTPPLTPSDSPQTRTASGAV 510
           P+P   PPP+  PP P G PP  P  +P   T + ++
Sbjct: 2   PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSL 38


>gi|24431935 reticulon 4 isoform A [Homo sapiens]
          Length = 1192

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 59/230 (25%), Positives = 91/230 (39%), Gaps = 32/230 (13%)

Query: 425 PGSPKKQKNESNSAGS---PADMELDSDMEVPHGSQSSESFQFQPPLPPDTPPLPRGTPP 481
           P +P++Q +   S  S   PA   L +    P      +    +PP PP     P+  P 
Sbjct: 99  PVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEP- 157

Query: 482 PVFTPPLP-KGTPPLTPSDSPQTRTASGAVDEDALTLE--------------ELEEQQ-R 525
            V+TPP P    PP TP+ +P+ R +SG+VDE    L               +L+EQ   
Sbjct: 158 -VWTPPAPAPAAPPSTPA-APKRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGN 215

Query: 526 RIWAALEQAESV--NSDSDVPVDTPLTGNSVASSPCPNELDLPVP-EGKTSEKQTLDEPE 582
            I A  E   SV   + + +P  +PL+  S         L   +P EG   E        
Sbjct: 216 TISAGQEDFPSVLLETAASLPSLSPLSAASFKEHEYLGNLSTVLPTEGTLQE-------N 268

Query: 583 VPEIFTKKSEAGHASSPDSEVTSLCQKEKAELAPVNTEGALLDNGSVVPN 632
           V E   + SE       D ++T   + E +E+    +     ++  +V N
Sbjct: 269 VSEASKEVSEKAKTLLIDRDLTEFSELEYSEMGSSFSVSPKAESAVIVAN 318


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
           sapiens]
          Length = 2462

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 59/270 (21%), Positives = 94/270 (34%), Gaps = 40/270 (14%)

Query: 408 QAPGVKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPP 467
           +A    + +  + S  SP +   +    N    PA +  D     P G  +        P
Sbjct: 720 EAEATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGP---PPGPPTPPPEDIPAP 776

Query: 468 LPPDTPPLPRGTPPPVFTPPLPKGTPPLTPSDSPQTRTASGAVDEDALTLEELEEQQRRI 527
             P       G P P   PP P   PP+ P +  +  TA+      A  +EE EEQ+   
Sbjct: 777 TEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAA------APPVEEGEEQKP-- 828

Query: 528 WAALEQAESVNSDSDVPVDTPLTGNSVASSPCPNELDLPVPEGKTSEKQTLDEPEVPEIF 587
             A E+       ++ PV           S C  E +    +GK +E          +  
Sbjct: 829 -PAAEELAVDTGKAEEPV----------KSECTEEAEEGPAKGKDAEAAEATAEGALKAE 877

Query: 588 TKKSEAGHASS-------PDSEVTSLCQKEKAELAPVNTEGALLD--NGSVVPNCD-ISN 637
            K+  +G A++        DS+ ++ C  ++ + A    +  LL      + P  D  +N
Sbjct: 878 KKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRAN 937

Query: 638 GGSQKLF--------PADTSPSTATKIHSP 659
              QK           A   P   TK+H P
Sbjct: 938 ASPQKPLDLKQLKQRAAAIPPIQVTKVHEP 967


>gi|29294655 melanoma antigen family C, 3 isoform 2 [Homo sapiens]
          Length = 346

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 5/119 (4%)

Query: 419 SSSHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLPPDTPPLPRG 478
           SS+ SS        + S S+ SP    L S + +             PPLP   P +P  
Sbjct: 40  SSTSSSSFHFLFPSSSSLSSSSPLSSPLPSTLILGVPEDEDMPAAGMPPLPQSPPEIPPQ 99

Query: 479 TPPPVFTPPLPKGTPPLTPSDSPQTRTASGAVDEDALTLEELEEQQRRIWAALEQAESV 537
            PP + +P  P  +PP +P DS  +      +DE++ +    EE+    W AL ++ES+
Sbjct: 100 GPPKI-SPQGPPQSPPQSPLDSCSSPLLWTRLDEESSS----EEEDTATWHALPESESL 153



 Score = 30.0 bits (66), Expect = 7.7
 Identities = 30/99 (30%), Positives = 40/99 (40%), Gaps = 9/99 (9%)

Query: 518 EELEEQQRRIWAALEQAESVNSDSD---VPVDTPLTGNSVASSPCPNELDLPVPEGKTSE 574
           E+L + Q  I    E A S +S S     P  + L+ +S  SSP P+ L L VPE +   
Sbjct: 23  EDLVDAQDSIDEEEEDASSTSSSSFHFLFPSSSSLSSSSPLSSPLPSTLILGVPEDEDMP 82

Query: 575 KQTL-----DEPEVPEIFTKK-SEAGHASSPDSEVTSLC 607
              +       PE+P     K S  G   SP       C
Sbjct: 83  AAGMPPLPQSPPEIPPQGPPKISPQGPPQSPPQSPLDSC 121


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 59/245 (24%), Positives = 81/245 (33%), Gaps = 40/245 (16%)

Query: 453  PHGSQSSESFQFQPPLPPDTPPLPRGTP----------PPVFTPPLPKGTPPLTP----S 498
            P G  ++ S +  P  P  TPP P+G P          PP  TPP PKG+P  TP    +
Sbjct: 973  PKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGA 1032

Query: 499  DSPQTRTASGAVDEDALTLEELEEQQRRIWAALEQAESVNSDSDVPVDTPLTGNSVASSP 558
             +P   T        A T            A    A ++ S    P    L G     +P
Sbjct: 1033 STPPAATPPSPKGSPAAT-------PLPKGAPTTPAATLPSPKGGPATPSLKG-----AP 1080

Query: 559  CPNELDLPVPEGKTSEKQTLDEPEVPEIFTKKSEAGHASSP----DSEVTSLCQKEKAEL 614
             P     P P+G  +       P  P       + G A+ P     +   +     K  L
Sbjct: 1081 TPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGL 1140

Query: 615  APVNTEGALLDNGSVVPNCDISNGG-------SQKLFPADTSPSTATKIHSPIPDMSKFA 667
            A    +GA     +  P+     GG            PA T PS    + +P P  +   
Sbjct: 1141 ATPPPKGAPTTPAATPPS---PKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1197

Query: 668  TGITP 672
               TP
Sbjct: 1198 PAATP 1202



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 61/246 (24%), Positives = 87/246 (35%), Gaps = 27/246 (10%)

Query: 423  SSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLPPDTPPLPRG---T 479
            ++P SPK      +  G+P           P G  ++ S +  P  P  TPP P+G   T
Sbjct: 1177 ATPPSPKGGLATPSPKGAPTTPAATPPS--PKGGLATPSPKGAPTTPAATPPSPKGGLAT 1234

Query: 480  PPPVFTPPLPKGTPPLTPSDSPQTRTASGAVDEDALTLEELEEQQRRIWAALEQAESVNS 539
            P P   P  P  TPP +P   P T    GA    A T   L+        A    +   +
Sbjct: 1235 PSPKGAPTTPAATPP-SPKGGPATPPPKGAPTPPAATPPSLKG-----GLATPPHKGAPN 1288

Query: 540  DSDVPVDTPLTGNSVA---SSPCPNELDLPVPEGKTSEKQTLDEPEVPEIFTKKSEAGHA 596
             + V   +P  G + +    +P P     P P+G          P  P + T  S  G  
Sbjct: 1289 PAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAV-TPPSPKGTP 1347

Query: 597  SSPDSEVTSLCQKEKAELAPVNTEGALLDNGSVVPNCDISNGGSQKLFPADTSPSTATKI 656
            + P +  +S    +     P + E      G   P    S+ G   + P   SP     I
Sbjct: 1348 TLPATTPSS----KGGPTTPSSKE------GPTPPAATPSHKGGPAMTP--PSPKRGPAI 1395

Query: 657  HSPIPD 662
             SP  D
Sbjct: 1396 PSPKGD 1401



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 47/198 (23%), Positives = 69/198 (34%), Gaps = 13/198 (6%)

Query: 408  QAPGVKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPP 467
            QAP +   +       +  +PK      +  G+P           P G  ++ S ++ P 
Sbjct: 907  QAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPS--PKGGPATPSPKWAPT 964

Query: 468  LPPDTPPLPRGTP--PPVFTPPLPKGTPPLTPSDSPQTRTASGAVDEDALTLEELEEQQR 525
             P  TPP P+G P  P     P P    P +P   P T +  GA    A+T    +    
Sbjct: 965  PPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA 1024

Query: 526  RI----WAALEQAESVNSDSDVPVDTPLTGNSVASSPCPNELDLPVPEGKTSEKQTLDEP 581
                   A+   A +  S    P  TPL       +P      LP P+G  +       P
Sbjct: 1025 ATPFPKGASTPPAATPPSPKGSPAATPLP----KGAPTTPAATLPSPKGGPATPSLKGAP 1080

Query: 582  EVPEIFTKKSEAGHASSP 599
              P   T  S  G  ++P
Sbjct: 1081 -TPPAATPPSPKGGPATP 1097



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 57/242 (23%), Positives = 79/242 (32%), Gaps = 20/242 (8%)

Query: 424  SPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLPPDTPPLPRGTPPPV 483
            +P SPK     S   G+P           P GS  +   +  P  P  TPP P+GTP   
Sbjct: 1293 TPPSPKGGPATSPPKGAPTPPAATPPS--PKGSPGTPPPKGAPTPPAVTPPSPKGTPTLP 1350

Query: 484  FTPPLPKGTPPLTPSDSPQTRTASGAVDEDALTLEELEEQQRRIWAALEQAESVNSDSDV 543
             T P  KG P    S    T  A+    +    +     ++           S   D   
Sbjct: 1351 ATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG------PAIPSPKGDPTS 1404

Query: 544  PVDTPLTGNSVASSPCPNELDLPVPEGKTSEKQTLDEPEVPEIFTKKSEAGHASSPDSEV 603
            P   PL+     ++P   E         T  K  L  P V  +  KK+ A   S+P    
Sbjct: 1405 PAVIPLSPKKAPATPVTRE------GAATPSKGDLTPPAVTPVSLKKAPA--TSAPKGGP 1456

Query: 604  TSLCQKEKAELAPVNTEGALLDNGSVVPNCDISNGGSQKLFPADTSPSTATKIHSPIPDM 663
             +   K    L  V             P   ++   S K  PA  +P  A  + + IP  
Sbjct: 1457 ATPSSKGDPTLPAVTPPS---PKEPPAPK-QVATSSSPKKAPATPAPMGAPTLPAVIPSS 1512

Query: 664  SK 665
             K
Sbjct: 1513 PK 1514



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 30/97 (30%), Positives = 39/97 (40%), Gaps = 6/97 (6%)

Query: 423  SSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLPPDTPPLPRG---T 479
            ++P SPK         G+P           P G  ++ S +  P  P  TPP P+G   T
Sbjct: 1154 ATPPSPKGGLATPPPKGAPTTPAATPPS--PKGGLATPSPKGAPTTPAATPPSPKGGLAT 1211

Query: 480  PPPVFTPPLPKGTPPLTPSDSPQTRTASGAVDEDALT 516
            P P   P  P  TPP +P     T +  GA    A T
Sbjct: 1212 PSPKGAPTTPAATPP-SPKGGLATPSPKGAPTTPAAT 1247



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 73/317 (23%), Positives = 107/317 (33%), Gaps = 81/317 (25%)

Query: 423  SSPGSPKKQKNESNSAGSPADMEL--DSDMEVPHGSQSSESFQFQPPLPPDTPPLPRGTP 480
            ++  SPKK        G+P    +   S  EVP    S        P+ P    L + TP
Sbjct: 1485 ATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRD-----PIAPTATLLSKKTP 1539

Query: 481  ----------PPVFTPPLPKGTPPL-TPSDSPQTRTASGAVDEDALTLEELE----EQQR 525
                      PP  T P PK TP + TP ++P T ++  A    A+T    +     ++ 
Sbjct: 1540 ATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKEL 1599

Query: 526  RIWAAL-------------------EQAESVNSDSDVPVDTPLTGNSVASSPC------- 559
             I  A+                   E+  +  +    P   P+T +S+  SP        
Sbjct: 1600 LIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTC 1659

Query: 560  -------PNELDLPVPEGKTSEKQTL--DEPEVPEIFTKKSEAGHASSPDSEVT-SLCQK 609
                        LP  +G T+ K+ L    PE   I T  +  G  +   S  +  +C  
Sbjct: 1660 KMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPD 1719

Query: 610  EKAELAPVNTEGALLDNGSVVPNCDISNGGSQKLFPADTSPSTATK----IHSP----IP 661
              A+            NGS  P   +S      L P     S   K     HSP     P
Sbjct: 1720 PSAK------------NGSKGP---LSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAP 1764

Query: 662  DMSKFATGITPFEFENM 678
              SK +T +T   FE +
Sbjct: 1765 PESKASTPLTAAAFEKV 1781



 Score = 37.0 bits (84), Expect = 0.063
 Identities = 56/248 (22%), Positives = 73/248 (29%), Gaps = 70/248 (28%)

Query: 423  SSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLPPDTPPLPRG---T 479
            ++P SPK      +  G+P           P G  ++ S +  P  P  TPP P+G   T
Sbjct: 1200 ATPPSPKGGLATPSPKGAPTTPAATPPS--PKGGLATPSPKGAPTTPAATPPSPKGGPAT 1257

Query: 480  PPP------------------------------VFTPPLPKGTP---------------P 494
            PPP                              V TPP PKG P               P
Sbjct: 1258 PPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATP 1317

Query: 495  LTPSDSPQTRTASGAVDEDALTLEELEEQQRRIWAALEQAESVNSDSDVPVDTPLTGNSV 554
             +P  SP T    GA    A+T                   S      +P  TP   +S 
Sbjct: 1318 PSPKGSPGTPPPKGAPTPPAVT-----------------PPSPKGTPTLPATTP---SSK 1357

Query: 555  ASSPCPNELDLPVPEGKTSEKQTLDEPEVPEIFTKKSEAGHASSPDSEVTSLCQKEKAEL 614
                 P+  + P P   T   +       P      +       P S        +KA  
Sbjct: 1358 GGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA 1417

Query: 615  APVNTEGA 622
             PV  EGA
Sbjct: 1418 TPVTREGA 1425



 Score = 36.6 bits (83), Expect = 0.082
 Identities = 61/263 (23%), Positives = 102/263 (38%), Gaps = 55/263 (20%)

Query: 424  SPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQP----PLPPDTPPLPRGT 479
            +P +P  ++  S  A +P+  +         G+ S +     P    P P + P  P  T
Sbjct: 1570 APATPSSKEASSPPAVTPSTYK---------GAPSPKELLIPPAVTSPSPKEAPTPPAVT 1620

Query: 480  PP-PVFTP--PLPKGTP---PLTPSDSPQTRTASGAVD-EDALTLEELEE--QQRRIWAA 530
            PP P   P  P PKGTP   P+TPS    + T+  +V  +   T+ +  +    ++   A
Sbjct: 1621 PPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTA 1680

Query: 531  LEQAESVNSDSDVPVDT------PLTGNSVASSP--CPNELDLPVPEGKTSEKQTLDE-P 581
            L++     +    P+ T      P T  S A+SP  CP+      P  K   K  L    
Sbjct: 1681 LKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPD------PSAKNGSKGPLSTVA 1734

Query: 582  EVPEIFTKKSEAGHASSPDSEVTSLCQKEKAELAPVNTEGALLDNGSVVPNCDISNGGSQ 641
              P +  +K  +  A   D+         K  LAP  ++           +  ++    +
Sbjct: 1735 PAPLLPVQKDSSKTAKGKDAS-----HSPKGPLAPPESKA----------STPLTAAAFE 1779

Query: 642  KLFPADTSPSTATKIHSPIPDMS 664
            K+ P    P +A+   +P P +S
Sbjct: 1780 KVLP---KPESASVSAAPSPPVS 1799



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 29/97 (29%), Positives = 38/97 (39%), Gaps = 6/97 (6%)

Query: 423  SSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLPPDTPPLPRG---T 479
            ++P SPK         G+P           P G  ++   +  P  P  TPP P+G   T
Sbjct: 1131 ATPPSPKGGLATPPPKGAPTTPAATPPS--PKGGLATPPPKGAPTTPAATPPSPKGGLAT 1188

Query: 480  PPPVFTPPLPKGTPPLTPSDSPQTRTASGAVDEDALT 516
            P P   P  P  TPP +P     T +  GA    A T
Sbjct: 1189 PSPKGAPTTPAATPP-SPKGGLATPSPKGAPTTPAAT 1224



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 58/266 (21%), Positives = 76/266 (28%), Gaps = 38/266 (14%)

Query: 439  GSPADMELDSDMEVPHGSQSSESFQFQPPLPPDTPPLPRGTPP----------------- 481
            G PA   L      P  +  S       P P   P  P  TPP                 
Sbjct: 1069 GGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT 1128

Query: 482  PVFTPPLPKG---TPPLTPSDSPQTRTASGAVDEDALTLEELEEQQRRIWAALEQAE--- 535
            P  TPP PKG   TPP  P  +P T  A+    +  L     +       A     +   
Sbjct: 1129 PAATPPSPKGGLATPP--PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1186

Query: 536  ---SVNSDSDVPVDTPLTGNSVASSPCPNELDL------PVPEGKTSEKQTLDEPEVPEI 586
               S       P  TP +     ++P P           P P+G  +       P  P  
Sbjct: 1187 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1246

Query: 587  FTKKSEAGHASSPDSEVTSLCQKEKAELAPVNTEGALLDNGSVVPNCDISNGGSQKLFPA 646
                 + G A+ P     +      A   P    G         PN  +    S K  PA
Sbjct: 1247 TPPSPKGGPATPPPKGAPT----PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPA 1302

Query: 647  DTSPSTATKIHSPIPDMSKFATGITP 672
             + P  A    +  P   K + G  P
Sbjct: 1303 TSPPKGAPTPPAATPPSPKGSPGTPP 1328



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 50/209 (23%), Positives = 75/209 (35%), Gaps = 27/209 (12%)

Query: 412  VKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDSDMEVP-HGSQSSESFQFQPPLPP 470
            V    KR  +      P       +S  SP +     +  +   GS+ S +    P    
Sbjct: 801  VSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSP---- 856

Query: 471  DTPPLPRGTP-PPVFTPPLPKGT---PPLTPSDS------PQTRTASGAVDE-DALTLEE 519
             TPP P+G P P   TP  PKG    P  TP+ S      P+   A+ A  +  AL++  
Sbjct: 857  -TPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTS 915

Query: 520  LEEQQRRIWAALEQAESVNSDSDVPV------DTPLTGNSVAS---SPCPNELDLPVPEG 570
               ++ R   A +   +  S    P        +P  G +  S   +P P     P P+G
Sbjct: 916  SSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKG 975

Query: 571  KTSEKQTLDEPEVPEIFTKKSEAGHASSP 599
              +       P  P   T  S  G  ++P
Sbjct: 976  GPATPSPKGAP-TPPAATPPSPKGGPATP 1003



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 26/77 (33%), Positives = 33/77 (42%), Gaps = 17/77 (22%)

Query: 423  SSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLPPDTPPLPRGTPPP 482
            ++P SPK         GSPA   L      P G+ ++ +     P      P  +G P P
Sbjct: 1038 ATPPSPK---------GSPAATPL------PKGAPTTPAATLPSPKGGPATPSLKGAPTP 1082

Query: 483  -VFTPPLPKGTPPLTPS 498
               TPP PKG  P TPS
Sbjct: 1083 PAATPPSPKG-GPATPS 1098


>gi|47519490 reticulon 4 isoform D [Homo sapiens]
          Length = 392

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 35/112 (31%), Positives = 51/112 (45%), Gaps = 7/112 (6%)

Query: 425 PGSPKKQKNESNSAGS---PADMELDSDMEVPHGSQSSESFQFQPPLPPDTPPLPRGTPP 481
           P +P++Q +   S  S   PA   L +    P      +    +PP PP     P+  P 
Sbjct: 99  PVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEP- 157

Query: 482 PVFTPPLP-KGTPPLTPSDSPQTRTASGAVDEDALTLEELEEQQRRIWAALE 532
            V+TPP P    PP TP+ +P+ R +SG+VDE    L    E   R  A ++
Sbjct: 158 -VWTPPAPAPAAPPSTPA-APKRRGSSGSVDETLFALPAASEPVIRSSAVVD 207


>gi|195963410 MEF2 activating motif and SAP domain containing
           transcriptional regulator isoform 1 [Homo sapiens]
          Length = 415

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 61/225 (27%), Positives = 88/225 (39%), Gaps = 39/225 (17%)

Query: 375 PRGIPDEWRIFGSIPMQACQQKDVFANYLTSNFQAPGVK-SGNK-----RSSSHSSPGSP 428
           P G+P        + +Q  + +++  + L    +  G+  SG K     R    + P   
Sbjct: 152 PPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRER 211

Query: 429 KKQKNESNSAGSPADMELDSDMEVPH--GSQSSESFQFQPPLP--PDTPPLPRGTPPPVF 484
            K + E + AG+P        +      GS    +   +PPLP   DTP    GT P   
Sbjct: 212 PKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTP----GTAPAPT 267

Query: 485 TPPLPKGTPPLTPSDSPQTRTASGAVDEDALTL-EELEEQQRR--------IWAALE-QA 534
             P P   P LTPS  P +          ALTL EEL+E  RR        I   LE Q 
Sbjct: 268 PTPAPAAAPALTPSSGPGSA---------ALTLEEELQEAIRRAQLLPNRGIDDILEDQV 318

Query: 535 ESVNSDSDVPVDTPLTGNSVASSPCPNEL------DLPVPEGKTS 573
           E  +    +P+D P + + ++ SP    L       LP P   +S
Sbjct: 319 EPDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSS 363


>gi|32698970 MEF2 activating motif and SAP domain containing
           transcriptional regulator isoform 2 [Homo sapiens]
          Length = 312

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 61/225 (27%), Positives = 88/225 (39%), Gaps = 39/225 (17%)

Query: 375 PRGIPDEWRIFGSIPMQACQQKDVFANYLTSNFQAPGVK-SGNK-----RSSSHSSPGSP 428
           P G+P        + +Q  + +++  + L    +  G+  SG K     R    + P   
Sbjct: 49  PPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRER 108

Query: 429 KKQKNESNSAGSPADMELDSDMEVPH--GSQSSESFQFQPPLP--PDTPPLPRGTPPPVF 484
            K + E + AG+P        +      GS    +   +PPLP   DTP    GT P   
Sbjct: 109 PKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTP----GTAPAPT 164

Query: 485 TPPLPKGTPPLTPSDSPQTRTASGAVDEDALTL-EELEEQQRR--------IWAALE-QA 534
             P P   P LTPS  P +          ALTL EEL+E  RR        I   LE Q 
Sbjct: 165 PTPAPAAAPALTPSSGPGSA---------ALTLEEELQEAIRRAQLLPNRGIDDILEDQV 215

Query: 535 ESVNSDSDVPVDTPLTGNSVASSPCPNEL------DLPVPEGKTS 573
           E  +    +P+D P + + ++ SP    L       LP P   +S
Sbjct: 216 EPDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSS 260


>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
           [Homo sapiens]
          Length = 1481

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 57/218 (26%), Positives = 86/218 (39%), Gaps = 40/218 (18%)

Query: 414 SGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLPP--- 470
           +G  +   +S     K  K +      P  + L  ++  P  +++SE  +  PPLP    
Sbjct: 478 TGKVKLDENSEKHLVKDLKAQGTRDSKP--IALKEEIVTPKETETSEK-ETPPPLPTIAS 534

Query: 471 DTPPLPRGTPPPVFTPPLP--------KGTPPLTPSD--------------SPQTRTASG 508
             PPLP  TPPP  TPPLP           PPL PS                P T + + 
Sbjct: 535 PPPPLPTTTPPPQ-TPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTS 593

Query: 509 AVDEDALTLEELE---EQQRRIWAALEQAESVNSDSDVPVDTPLTGNSVASSPCPNELDL 565
           AV   A +   ++   + Q  + AA+   ++ ++   +P+   L G+    SP       
Sbjct: 594 AVSSQANSQPPVQVSVKTQVSVTAAIPHLKT-STLPPLPLPPLLPGDDDMDSPKETLPSK 652

Query: 566 PVPEGKTSEKQTL--DEPEVPEIFTKKSEAGHASSPDS 601
           PV + K    + L  D P  PE+       G  S PDS
Sbjct: 653 PVKKEKEQRTRHLLTDLPLPPEL-----PGGDLSPPDS 685


>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
           [Homo sapiens]
          Length = 1490

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 57/218 (26%), Positives = 86/218 (39%), Gaps = 40/218 (18%)

Query: 414 SGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLPP--- 470
           +G  +   +S     K  K +      P  + L  ++  P  +++SE  +  PPLP    
Sbjct: 478 TGKVKLDENSEKHLVKDLKAQGTRDSKP--IALKEEIVTPKETETSEK-ETPPPLPTIAS 534

Query: 471 DTPPLPRGTPPPVFTPPLP--------KGTPPLTPSD--------------SPQTRTASG 508
             PPLP  TPPP  TPPLP           PPL PS                P T + + 
Sbjct: 535 PPPPLPTTTPPPQ-TPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTS 593

Query: 509 AVDEDALTLEELE---EQQRRIWAALEQAESVNSDSDVPVDTPLTGNSVASSPCPNELDL 565
           AV   A +   ++   + Q  + AA+   ++ ++   +P+   L G+    SP       
Sbjct: 594 AVSSQANSQPPVQVSVKTQVSVTAAIPHLKT-STLPPLPLPPLLPGDDDMDSPKETLPSK 652

Query: 566 PVPEGKTSEKQTL--DEPEVPEIFTKKSEAGHASSPDS 601
           PV + K    + L  D P  PE+       G  S PDS
Sbjct: 653 PVKKEKEQRTRHLLTDLPLPPEL-----PGGDLSPPDS 685



 Score = 31.6 bits (70), Expect = 2.6
 Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 3/45 (6%)

Query: 466  PP--LPPDT-PPLPRGTPPPVFTPPLPKGTPPLTPSDSPQTRTAS 507
            PP  LPP+  PP P G PPP   PPL +G     P +     TA+
Sbjct: 1256 PPHILPPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAA 1300


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 55/212 (25%), Positives = 79/212 (37%), Gaps = 30/212 (14%)

Query: 466  PPLPPDTPPLPRGTPPPVFTPPLPKGTPPLTPSDSPQTRTASGAV--DEDALTLEE---L 520
            PPLPP+ PP           PPLP   PP+TP   P+      A+  ++ ALT E     
Sbjct: 1147 PPLPPEEPPT---------MPPLPPEEPPMTPPLPPEEPPEGPALPTEQSALTAENTWPT 1197

Query: 521  EEQQRRIWAALEQAESVNSDSDVPVDTPLTGNSVASSPCPNELDLPVPEGKTSEKQTLDE 580
            E        ++ Q E   S S++   + +  +   S+  P+ L   V E   +  +   E
Sbjct: 1198 EVPSSPSEESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVL---VSEAAVTVPEPPPE 1254

Query: 581  PEVPEIFTKKSEA----GHASSPDSEVTSLCQKEKAELA---------PVNTEGALLDNG 627
            PE     T    A     H   P+  VT +  +  A  A         PV +E A   + 
Sbjct: 1255 PESSITLTPVESAVVAEEHEVVPERPVTCMVSETPAMSAEPTVLASEPPVMSETAETFDS 1314

Query: 628  SVVPNCDISNGGSQKLFPADTSPSTATKIHSP 659
                    S   +  L PA T+P  A  I  P
Sbjct: 1315 MRASGHVASEVSTSLLVPAVTTPVLAESILEP 1346


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 55/212 (25%), Positives = 79/212 (37%), Gaps = 30/212 (14%)

Query: 466  PPLPPDTPPLPRGTPPPVFTPPLPKGTPPLTPSDSPQTRTASGAV--DEDALTLEE---L 520
            PPLPP+ PP           PPLP   PP+TP   P+      A+  ++ ALT E     
Sbjct: 1147 PPLPPEEPPT---------MPPLPPEEPPMTPPLPPEEPPEGPALPTEQSALTAENTWPT 1197

Query: 521  EEQQRRIWAALEQAESVNSDSDVPVDTPLTGNSVASSPCPNELDLPVPEGKTSEKQTLDE 580
            E        ++ Q E   S S++   + +  +   S+  P+ L   V E   +  +   E
Sbjct: 1198 EVPSSPSEESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVL---VSEAAVTVPEPPPE 1254

Query: 581  PEVPEIFTKKSEA----GHASSPDSEVTSLCQKEKAELA---------PVNTEGALLDNG 627
            PE     T    A     H   P+  VT +  +  A  A         PV +E A   + 
Sbjct: 1255 PESSITLTPVESAVVAEEHEVVPERPVTCMVSETPAMSAEPTVLASEPPVMSETAETFDS 1314

Query: 628  SVVPNCDISNGGSQKLFPADTSPSTATKIHSP 659
                    S   +  L PA T+P  A  I  P
Sbjct: 1315 MRASGHVASEVSTSLLVPAVTTPVLAESILEP 1346


>gi|5730045 solute carrier family 16, member 2 [Homo sapiens]
          Length = 613

 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 33/100 (33%), Positives = 44/100 (44%), Gaps = 9/100 (9%)

Query: 413 KSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLPPDT 472
           +SG+   SSHS P +   Q   S  A  P   E D + + P GS   ES   +P   P+ 
Sbjct: 60  QSGSSGPSSHSPPAAMALQSQASEEAKGPW-QEADQEQQEPVGSPEPES---EPEPEPEP 115

Query: 473 PPLPRGTPPPVFTPPLPKGTPPLTPSDSPQTRTASGAVDE 512
            P+P   PPP    P P+  P   P+  P+    S  V E
Sbjct: 116 EPVP--VPPP---EPQPEPQPLPDPAPLPELEFESERVHE 150


>gi|56549694 enabled homolog isoform a [Homo sapiens]
          Length = 591

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 22/44 (50%), Positives = 22/44 (50%), Gaps = 1/44 (2%)

Query: 466 PPLPPDTPPLPR-GTPPPVFTPPLPKGTPPLTPSDSPQTRTASG 508
           PP PP  PPLP  G PPP   PPLP   PP  P        ASG
Sbjct: 333 PPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPASG 376



 Score = 38.1 bits (87), Expect = 0.028
 Identities = 30/98 (30%), Positives = 36/98 (36%), Gaps = 17/98 (17%)

Query: 417 KRSSSHSSPGSPKKQKNE---SNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLPPDTP 473
           +R SS ++P S +   N     +SA  P         E P    S +     P  PP  P
Sbjct: 262 RRISSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETP----SQQGIVLGPLAPPPPP 317

Query: 474 PLPRG----------TPPPVFTPPLPKGTPPLTPSDSP 501
           PLP G           P P   PPLP   PP  P   P
Sbjct: 318 PLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPP 355


>gi|39930375 enabled homolog isoform b [Homo sapiens]
          Length = 570

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 22/44 (50%), Positives = 22/44 (50%), Gaps = 1/44 (2%)

Query: 466 PPLPPDTPPLPR-GTPPPVFTPPLPKGTPPLTPSDSPQTRTASG 508
           PP PP  PPLP  G PPP   PPLP   PP  P        ASG
Sbjct: 333 PPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPASG 376



 Score = 38.1 bits (87), Expect = 0.028
 Identities = 30/98 (30%), Positives = 36/98 (36%), Gaps = 17/98 (17%)

Query: 417 KRSSSHSSPGSPKKQKNE---SNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLPPDTP 473
           +R SS ++P S +   N     +SA  P         E P    S +     P  PP  P
Sbjct: 262 RRISSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETP----SQQGIVLGPLAPPPPP 317

Query: 474 PLPRG----------TPPPVFTPPLPKGTPPLTPSDSP 501
           PLP G           P P   PPLP   PP  P   P
Sbjct: 318 PLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPP 355


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 31/90 (34%), Positives = 40/90 (44%), Gaps = 21/90 (23%)

Query: 423 SSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLPPDTPPLPRGTP-- 480
           S P +P  Q   + S GSP               Q++ SF   PPL P   P P+  P  
Sbjct: 356 SPPATPPSQA--TTSLGSPT-------------LQATHSFLPSPPLSPLATPPPQAPPAL 400

Query: 481 --PPVFTPPLPKGTPPLTP--SDSPQTRTA 506
             PP+  PP P  +PPL+P  + SPQ   A
Sbjct: 401 ALPPLQAPPSPPASPPLSPLATPSPQAPNA 430



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 33/99 (33%), Positives = 43/99 (43%), Gaps = 5/99 (5%)

Query: 404 TSNFQAPGVKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQ 463
           T + QAP   + +   +  S P SP  Q   S  A  P         + P  S ++   Q
Sbjct: 422 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP-SLAAPPLQ 480

Query: 464 FQPPLPPDTPPL-PRGTPPPVFTPPLPKGTPPLTPSDSP 501
             PP PP +PP+ P  TPPP   PPL    PPL  +  P
Sbjct: 481 V-PPSPPASPPMSPSATPPPQAPPPL--AAPPLQLAKPP 516



 Score = 37.4 bits (85), Expect = 0.048
 Identities = 30/105 (28%), Positives = 45/105 (42%), Gaps = 13/105 (12%)

Query: 408 QAPGVKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPP 467
           QAP   +     +  S P SP      + S  +P  + +   ++ P     S   Q  P 
Sbjct: 395 QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL-LQAPFSPPPSPPVQ-APF 452

Query: 468 LPPDTPPL-PRGTPP----------PVFTPPLPKGTPPLTPSDSP 501
            PP +PP+ P  TPP          P+  PP P  +PP++PS +P
Sbjct: 453 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 497



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 23/62 (37%)

Query: 466 PPLPPDTPPL-PRGTP----------------------PPVFTPPLPKGTPPLTPSDSPQ 502
           PP PP +PPL P  TP                      PPV  P  P  +PP++PS +P 
Sbjct: 408 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 467

Query: 503 TR 504
           ++
Sbjct: 468 SQ 469



 Score = 31.2 bits (69), Expect = 3.5
 Identities = 40/175 (22%), Positives = 64/175 (36%), Gaps = 16/175 (9%)

Query: 412 VKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDSDME-VPHGSQSSESFQFQPPLPP 470
           V S ++ S++  SP + +++ +       PA   L S    +   ++S  S +  P  P 
Sbjct: 209 VSSASEHSTTEPSPAA-RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA 267

Query: 471 D-TPPLPRGTP---PPVFTPPLPKGTPPLTPSDSPQTRTASGAVDEDALTLEELEEQQRR 526
             + P P+G     PP  TPP     P L P  S    T S +          L+ Q   
Sbjct: 268 HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA--------ALQSQAPP 319

Query: 527 IWAALEQAESVNSDSDVPVDTPLTGNSVASSPCPNELDLPVPEGKTSEKQTLDEP 581
              A   + S+      P+  PL   S ++ P    L  P     +    +L  P
Sbjct: 320 TLPATPHSSSLTCQLATPL--PLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSP 372



 Score = 30.0 bits (66), Expect = 7.7
 Identities = 34/114 (29%), Positives = 43/114 (37%), Gaps = 10/114 (8%)

Query: 453 PHGSQSSESFQFQPPLPPDTPPLPRGTPPPVFTPPLPKGTPP---LTPSDSPQTRTASGA 509
           PH S  S + Q   PLP   PP P   PP + T P P  TPP    T   SP  +     
Sbjct: 325 PHSS--SLTCQLATPLPL-APPSP-SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSF 380

Query: 510 VDEDALTLEELEEQQRRIWAALEQAESVNSDSDVPVDTPLTGNSVASSPCPNEL 563
           +    L+       Q     AL   ++  S    P   PL+  +  S   PN L
Sbjct: 381 LPSPPLSPLATPPPQAPPALALPPLQAPPSP---PASPPLSPLATPSPQAPNAL 431


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 31/90 (34%), Positives = 40/90 (44%), Gaps = 21/90 (23%)

Query: 423 SSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLPPDTPPLPRGTP-- 480
           S P +P  Q   + S GSP               Q++ SF   PPL P   P P+  P  
Sbjct: 317 SPPATPPSQA--TTSLGSPT-------------LQATHSFLPSPPLSPLATPPPQAPPAL 361

Query: 481 --PPVFTPPLPKGTPPLTP--SDSPQTRTA 506
             PP+  PP P  +PPL+P  + SPQ   A
Sbjct: 362 ALPPLQAPPSPPASPPLSPLATPSPQAPNA 391



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 33/99 (33%), Positives = 43/99 (43%), Gaps = 5/99 (5%)

Query: 404 TSNFQAPGVKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQ 463
           T + QAP   + +   +  S P SP  Q   S  A  P         + P  S ++   Q
Sbjct: 383 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP-SLAAPPLQ 441

Query: 464 FQPPLPPDTPPL-PRGTPPPVFTPPLPKGTPPLTPSDSP 501
             PP PP +PP+ P  TPPP   PPL    PPL  +  P
Sbjct: 442 V-PPSPPASPPMSPSATPPPQAPPPL--AAPPLQLAKPP 477



 Score = 37.4 bits (85), Expect = 0.048
 Identities = 30/105 (28%), Positives = 45/105 (42%), Gaps = 13/105 (12%)

Query: 408 QAPGVKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPP 467
           QAP   +     +  S P SP      + S  +P  + +   ++ P     S   Q  P 
Sbjct: 356 QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL-LQAPFSPPPSPPVQ-APF 413

Query: 468 LPPDTPPL-PRGTPP----------PVFTPPLPKGTPPLTPSDSP 501
            PP +PP+ P  TPP          P+  PP P  +PP++PS +P
Sbjct: 414 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 458



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 23/62 (37%)

Query: 466 PPLPPDTPPL-PRGTP----------------------PPVFTPPLPKGTPPLTPSDSPQ 502
           PP PP +PPL P  TP                      PPV  P  P  +PP++PS +P 
Sbjct: 369 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 428

Query: 503 TR 504
           ++
Sbjct: 429 SQ 430



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 38/154 (24%), Positives = 52/154 (33%), Gaps = 9/154 (5%)

Query: 413 KSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLPPDT 472
           +SG     +  +P  P + K +   A  P  +        P     S S    P   P  
Sbjct: 245 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS--PSA 302

Query: 473 PPLPRGTPPPVFTPPLPKGTPP---LTPSDSPQTRTASGAVDEDALTLEELEEQQRRIWA 529
           PP P   PP + T P P  TPP    T   SP  +     +    L+       Q     
Sbjct: 303 PPSP-SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 361

Query: 530 ALEQAESVNSDSDVPVDTPLTGNSVASSPCPNEL 563
           AL   ++  S    P   PL+  +  S   PN L
Sbjct: 362 ALPPLQAPPSP---PASPPLSPLATPSPQAPNAL 392


>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
          Length = 3703

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 18/37 (48%), Positives = 22/37 (59%), Gaps = 1/37 (2%)

Query: 466  PPLPPDTPPLPRGTPPPVFTPPLPKGTPPLT-PSDSP 501
            PP PP  PPLP   P P  TP +P   PP+T P+ +P
Sbjct: 2042 PPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAP 2078



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 24/79 (30%), Positives = 32/79 (40%), Gaps = 6/79 (7%)

Query: 411  GVKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLPP 470
            G+ S    S    + G P K  + S S+ +PA   +    + P   Q  +    Q P   
Sbjct: 3153 GLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPPQQQQQQ----QQPQVQ 3208

Query: 471  DTPPLPRGTPPPVFTPPLP 489
              PP P   PPP  TP LP
Sbjct: 3209 QPPPPPAAQPPP--TPQLP 3225



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 18/60 (30%), Positives = 30/60 (50%), Gaps = 2/60 (3%)

Query: 462  FQFQPPLPPDTPPLPRGTPPPV-FTPPLPKGTPPLTPSDSPQTRTASGAVDEDALTLEEL 520
            +  +P  P   PP P   PPP+   PP P  TP + P+ +P   + + A  + ++ L +L
Sbjct: 2030 YPLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAI-PASAPPITSPTIAPAQPSVPLTQL 2088


>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo
           sapiens]
          Length = 1758

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 17/28 (60%), Positives = 18/28 (64%)

Query: 467 PLPPDTPPLPRGTPPPVFTPPLPKGTPP 494
           P PP T PLP G PPP F+P  P G PP
Sbjct: 566 PPPPHTLPLPPGVPPPQFSPQFPPGQPP 593



 Score = 34.3 bits (77), Expect = 0.41
 Identities = 23/50 (46%), Positives = 24/50 (48%), Gaps = 7/50 (14%)

Query: 458 SSESFQFQPPLPPDTP-----PLPRGTPPPVFTPPLPKGTPPLTPSDSPQ 502
           S  S + Q P  P TP     P P   PPP  T PLP G PP  P  SPQ
Sbjct: 539 SERSQRTQGPSLPATPVFVPVPPPPLYPPPPHTLPLPPGVPP--PQFSPQ 586



 Score = 33.9 bits (76), Expect = 0.53
 Identities = 26/69 (37%), Positives = 31/69 (44%), Gaps = 6/69 (8%)

Query: 463 QFQPPLPPDTPPLPRG--TPPPVFTPPLPKGTPPLTPSDSPQTRTASGAVDEDA--LTLE 518
           QF P  PP  PP P G   PPP F PP P        S   QT  ++      A  L+ E
Sbjct: 582 QFSPQFPPGQPP-PAGYSVPPPGF-PPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSRE 639

Query: 519 ELEEQQRRI 527
           E   +QRR+
Sbjct: 640 EFYREQRRL 648


>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo
           sapiens]
          Length = 1792

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 17/28 (60%), Positives = 18/28 (64%)

Query: 467 PLPPDTPPLPRGTPPPVFTPPLPKGTPP 494
           P PP T PLP G PPP F+P  P G PP
Sbjct: 566 PPPPHTLPLPPGVPPPQFSPQFPPGQPP 593



 Score = 34.3 bits (77), Expect = 0.41
 Identities = 23/50 (46%), Positives = 24/50 (48%), Gaps = 7/50 (14%)

Query: 458 SSESFQFQPPLPPDTP-----PLPRGTPPPVFTPPLPKGTPPLTPSDSPQ 502
           S  S + Q P  P TP     P P   PPP  T PLP G PP  P  SPQ
Sbjct: 539 SERSQRTQGPSLPATPVFVPVPPPPLYPPPPHTLPLPPGVPP--PQFSPQ 586



 Score = 33.9 bits (76), Expect = 0.53
 Identities = 26/69 (37%), Positives = 31/69 (44%), Gaps = 6/69 (8%)

Query: 463 QFQPPLPPDTPPLPRG--TPPPVFTPPLPKGTPPLTPSDSPQTRTASGAVDEDA--LTLE 518
           QF P  PP  PP P G   PPP F PP P        S   QT  ++      A  L+ E
Sbjct: 582 QFSPQFPPGQPP-PAGYSVPPPGF-PPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSRE 639

Query: 519 ELEEQQRRI 527
           E   +QRR+
Sbjct: 640 EFYREQRRL 648


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 25/67 (37%), Positives = 34/67 (50%), Gaps = 2/67 (2%)

Query: 443 DMELDSDMEVPHGSQSSESFQFQPP-LPPDTPPLPRG-TPPPVFTPPLPKGTPPLTPSDS 500
           D E  SD+E+   S S +S    P  LPP  PP P G TPPP+     P  +PP+   + 
Sbjct: 769 DKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEE 828

Query: 501 PQTRTAS 507
           P+   A+
Sbjct: 829 PEELPAA 835



 Score = 35.4 bits (80), Expect = 0.18
 Identities = 53/217 (24%), Positives = 75/217 (34%), Gaps = 27/217 (12%)

Query: 452  VPHGSQSSESFQFQPPLPPDTPPLPRGTPPPVFTPP---LPKGT-----PPLTPSDSPQT 503
            VP   +  E      PLPP  PP P   P PV  PP   +P+GT     PP    D    
Sbjct: 823  VPAKEEPEELPAAPGPLPPPPPP-PPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVI 881

Query: 504  RTASGAVDEDALTLEELEEQQRRIWAALEQAESVNSDSDVPVDTPLTGNSVASSPC---P 560
               S   DE+    EE EE++       E  E    D +   +                 
Sbjct: 882  NINSS--DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEE 939

Query: 561  NELDLPVPEGKTSEKQTLDEPEVPEIFTKKSEAGHASSPDSEVTSLC----QKEKAELAP 616
             EL+    E    E++ L+E E  E  T   E    + P   +           K +  P
Sbjct: 940  GELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEP 999

Query: 617  VNTEGALLDNGSVVPNCDISNGGSQKLFPADTSPSTA 653
                G LL         ++   G+++   ADT+P+ A
Sbjct: 1000 EPEPGLLL---------EVEEPGTEEERGADTAPTLA 1027



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 43/189 (22%), Positives = 63/189 (33%), Gaps = 30/189 (15%)

Query: 432  KNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLPPDTPPLPRGTPPPVFTPPLPKG 491
            + E        + EL+   ++  G+   E  +  PP P   P LP    PP   P     
Sbjct: 943  EEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPE 1002

Query: 492  TPPLTPSDSPQTRTASGAVDEDALTLEELEEQQRRIWAALEQAESVNSDSDVPVDTPLTG 551
               L   + P T    GA     L  E L  Q                      +    G
Sbjct: 1003 PGLLLEVEEPGTEEERGADTAPTLAPEALPSQG---------------------EVEREG 1041

Query: 552  NSVASSPCPNELDLPVPEGKTSEKQTLDEPEVPEIFTK-----KSEAGHASSPDSEVTSL 606
             S A+ P P EL     E + S   TL E E  +   K     ++ A      ++E  +L
Sbjct: 1042 ESPAAGPPPQEL----VEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEAL 1097

Query: 607  CQKEKAELA 615
             +KE+ + A
Sbjct: 1098 QEKEQDDTA 1106


>gi|20162568 melanoma antigen family C, 3 isoform 1 [Homo sapiens]
          Length = 643

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 5/72 (6%)

Query: 466 PPLPPDTPPLPRGTPPPVFTPPLPKGTPPLTPSDSPQTRTASGAVDEDALTLEELEEQQR 525
           PPLP   P +P   PP + +P  P  +PP +P DS  +      +DE++ +    EE+  
Sbjct: 385 PPLPQSPPEIPPQGPPKI-SPQGPPQSPPQSPLDSCSSPLLWTRLDEESSS----EEEDT 439

Query: 526 RIWAALEQAESV 537
             W AL ++ES+
Sbjct: 440 ATWHALPESESL 451


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 24/57 (42%), Positives = 27/57 (47%), Gaps = 1/57 (1%)

Query: 438  AGSPADMELDSDMEVPHGSQSSESFQFQPPLPPDTPPLPRGTPPPVFTPPLPKGTPP 494
            +GSP+   L +    P    SS     QPP PP  PP P   PPP   PPLP  T P
Sbjct: 2378 SGSPSVSSLPAKPR-PFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 41/186 (22%), Positives = 70/186 (37%), Gaps = 24/186 (12%)

Query: 417 KRSSSHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLPPDTPPLP 476
           K+ + H SP +  KQ  E++S   PA          P    S  S Q + P+  D P  P
Sbjct: 708 KQPTLHGSPSAKAKQPPEADSLSKPA----------PPKEPSVPSEQDKAPVADDKPKQP 757

Query: 477 RGTPPPVFTPPLPKGTPPLTPSDSPQTRTASGAVDEDALTLEELEEQQRRIWAALEQAES 536
           +   P   T  L   +   T  D P ++  S A  E+  T     +  +   +     E 
Sbjct: 758 KMVKP---TTDLVSSSSATTKPDIPSSKVQSQA--EEKTTPPLKTDSAKPSQSFPPTGEK 812

Query: 537 VNSDSDVPVDTPLTGNSVASSPCPNELDLPVPEGKTSEKQTLDEPEVPEIFTKKSEAGHA 596
           V+      +  P + + + S P P+           S+ Q   +P   +   KK++   +
Sbjct: 813 VSPFDSKAIPRPASDSKIISHPGPS---------SESKGQKQVDPVQKKEEPKKAQTKMS 863

Query: 597 SSPDSE 602
             PD++
Sbjct: 864 PKPDAK 869



 Score = 34.3 bits (77), Expect = 0.41
 Identities = 39/164 (23%), Positives = 58/164 (35%), Gaps = 6/164 (3%)

Query: 420 SSHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLPPDTPP--LPR 477
           S  S   + KKQK      G P  +      + P      +    + PL  D  P  +  
Sbjct: 182 SEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISS 241

Query: 478 GTPPPVFTPPLPKGTPPLTPSDSPQTRTASGAVDEDALTLEELEEQQRRIWAALEQAESV 537
             P  + + P   G P   P+ +PQT  A   +  DA      + +Q  I        S+
Sbjct: 242 QQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDA---SRPQTKQADIVRGESVKPSL 298

Query: 538 NSDSDVPVDTPLTGNSVASSPCPNELDLPVPEGKTSEKQTLDEP 581
            S S  P+  P  G   A  P  +E   P P    ++   L +P
Sbjct: 299 PSPSKPPIQQPTPGKPPAQQP-GHEKSQPGPAKPPAQPSGLTKP 341



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 31/115 (26%), Positives = 45/115 (39%), Gaps = 22/115 (19%)

Query: 410 PGVKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSES-------- 461
           P +K+ + + S    P   K    +S +   PA    DS + + H   SSES        
Sbjct: 793 PPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPAS---DSKI-ISHPGPSSESKGQKQVDP 848

Query: 462 ---------FQFQPPLPPDTPPLPRGTPPPVFTPPLPKGTPPLTPSDSPQTRTAS 507
                     Q +    PD  P+P+G+P P    P    T P TP  SP+ +  S
Sbjct: 849 VQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVP-TPQQSPKPQEQS 902


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 24/57 (42%), Positives = 27/57 (47%), Gaps = 1/57 (1%)

Query: 438  AGSPADMELDSDMEVPHGSQSSESFQFQPPLPPDTPPLPRGTPPPVFTPPLPKGTPP 494
            +GSP+   L +    P    SS     QPP PP  PP P   PPP   PPLP  T P
Sbjct: 2378 SGSPSVSSLPAKPR-PFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 41/186 (22%), Positives = 70/186 (37%), Gaps = 24/186 (12%)

Query: 417 KRSSSHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLPPDTPPLP 476
           K+ + H SP +  KQ  E++S   PA          P    S  S Q + P+  D P  P
Sbjct: 708 KQPTLHGSPSAKAKQPPEADSLSKPA----------PPKEPSVPSEQDKAPVADDKPKQP 757

Query: 477 RGTPPPVFTPPLPKGTPPLTPSDSPQTRTASGAVDEDALTLEELEEQQRRIWAALEQAES 536
           +   P   T  L   +   T  D P ++  S A  E+  T     +  +   +     E 
Sbjct: 758 KMVKP---TTDLVSSSSATTKPDIPSSKVQSQA--EEKTTPPLKTDSAKPSQSFPPTGEK 812

Query: 537 VNSDSDVPVDTPLTGNSVASSPCPNELDLPVPEGKTSEKQTLDEPEVPEIFTKKSEAGHA 596
           V+      +  P + + + S P P+           S+ Q   +P   +   KK++   +
Sbjct: 813 VSPFDSKAIPRPASDSKIISHPGPS---------SESKGQKQVDPVQKKEEPKKAQTKMS 863

Query: 597 SSPDSE 602
             PD++
Sbjct: 864 PKPDAK 869



 Score = 34.3 bits (77), Expect = 0.41
 Identities = 39/164 (23%), Positives = 58/164 (35%), Gaps = 6/164 (3%)

Query: 420 SSHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSESFQFQPPLPPDTPP--LPR 477
           S  S   + KKQK      G P  +      + P      +    + PL  D  P  +  
Sbjct: 182 SEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISS 241

Query: 478 GTPPPVFTPPLPKGTPPLTPSDSPQTRTASGAVDEDALTLEELEEQQRRIWAALEQAESV 537
             P  + + P   G P   P+ +PQT  A   +  DA      + +Q  I        S+
Sbjct: 242 QQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDA---SRPQTKQADIVRGESVKPSL 298

Query: 538 NSDSDVPVDTPLTGNSVASSPCPNELDLPVPEGKTSEKQTLDEP 581
            S S  P+  P  G   A  P  +E   P P    ++   L +P
Sbjct: 299 PSPSKPPIQQPTPGKPPAQQP-GHEKSQPGPAKPPAQPSGLTKP 341



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 31/115 (26%), Positives = 45/115 (39%), Gaps = 22/115 (19%)

Query: 410 PGVKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDSDMEVPHGSQSSES-------- 461
           P +K+ + + S    P   K    +S +   PA    DS + + H   SSES        
Sbjct: 793 PPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPAS---DSKI-ISHPGPSSESKGQKQVDP 848

Query: 462 ---------FQFQPPLPPDTPPLPRGTPPPVFTPPLPKGTPPLTPSDSPQTRTAS 507
                     Q +    PD  P+P+G+P P    P    T P TP  SP+ +  S
Sbjct: 849 VQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVP-TPQQSPKPQEQS 902


>gi|149999615 variable charge, X-linked 3B [Homo sapiens]
          Length = 216

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 51/216 (23%), Positives = 86/216 (39%), Gaps = 32/216 (14%)

Query: 409 APGVKSGNKRSSSHSSPGSPKK------------QKNESNSAGSPADMELDSDMEVPHGS 456
           A   ++G ++SSS  SP  PKK            ++      G+   M   +  E   G 
Sbjct: 12  AKAKEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAESGP 71

Query: 457 QSSESFQFQPPLPPDTP--PLPRGTPPPVFTPPLPKGT--PPLTPSDSPQTRTASGAVDE 512
            +        P P D P   LP+   PP    P+ +GT   PL+     +   +  +  E
Sbjct: 72  AA--------PGPSDQPSQELPQHELPP--EEPVSEGTQHDPLSQESELEEPLSQESEVE 121

Query: 513 DALTLEELEEQQRRIWAALEQAESVNSDSDVPVDTPLTGNSVASSPCPNE--LDLPVPEG 570
           + L+ E   E+     + +E+  S  S     V+ PL+  S    P   E  ++ P+ + 
Sbjct: 122 EPLSQESQVEEPLSQESEVEEPLSQESQ----VEEPLSQESEVEEPLSQESQVEEPLSQE 177

Query: 571 KTSEKQTLDEPEVPEIFTKKSEAGHASSPDSEVTSL 606
              E+    E +V E  +++SE     S +SE+  L
Sbjct: 178 SEMEEPLSQESQVEEPLSQESEMEEPLSQESEMEEL 213


>gi|239753435 PREDICTED: hypothetical protein XP_002345651 [Homo
           sapiens]
          Length = 218

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 25/87 (28%), Positives = 35/87 (40%), Gaps = 2/87 (2%)

Query: 465 QPPLPPDTP-PLPRGTPPPVFTPPLPKGTPPLTPSDSPQTRTASGAVDEDALTLEELEEQ 523
           +PP PP  P PLP   P P   PP P   PPL P   P+  +  G           +   
Sbjct: 32  KPPRPPKPPRPLPPNPPRPPLPPPRPP-KPPLPPPRPPKPPSPLGLAQSKVTLFPSISPS 90

Query: 524 QRRIWAALEQAESVNSDSDVPVDTPLT 550
                AAL  +  + S    P++ P++
Sbjct: 91  SMASLAALASSSLLKSTKPNPLEDPVS 117


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.130    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,323,286
Number of Sequences: 37866
Number of extensions: 1837197
Number of successful extensions: 16362
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 183
Number of HSP's successfully gapped in prelim test: 615
Number of HSP's that attempted gapping in prelim test: 10418
Number of HSP's gapped (non-prelim): 3968
length of query: 707
length of database: 18,247,518
effective HSP length: 109
effective length of query: 598
effective length of database: 14,120,124
effective search space: 8443834152
effective search space used: 8443834152
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.