Search of human proteins with 37577126

Search of human proteins with 37577126

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|37577126 ubiquitin conjugating enzyme E2, J2 isoform 1 [Homo
sapiens]
         (275 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|37577126 ubiquitin conjugating enzyme E2, J2 isoform 1 [Homo ...   566   e-162
gi|37577124 ubiquitin conjugating enzyme E2, J2 isoform 2 [Homo ...   521   e-148
gi|37577132 ubiquitin conjugating enzyme E2, J2 isoform 3 [Homo ...   425   e-119
gi|37577130 ubiquitin conjugating enzyme E2, J2 isoform 3 [Homo ...   425   e-119
gi|37577122 ubiquitin-conjugating enzyme E2, J1 [Homo sapiens]        123   2e-28
gi|4507779 ubiquitin-conjugating enzyme E2E 1 isoform 1 [Homo sa...    67   1e-11
gi|4507771 ubiquitin-conjugating enzyme E2B [Homo sapiens]             67   2e-11
gi|22749327 ubiquitin-conjugating enzyme E2E 2 [Homo sapiens]          66   3e-11
gi|33359694 ubiquitin-conjugating enzyme E2E 3 [Homo sapiens]          66   3e-11
gi|5454146 ubiquitin-conjugating enzyme E2E 3 [Homo sapiens]           66   3e-11
gi|32967280 ubiquitin-conjugating enzyme E2A isoform 1 [Homo sap...    66   3e-11
gi|8393719 ubiquitin-conjugating enzyme E2D 4 (putative) [Homo s...    60   3e-09
gi|150417999 ubiquitin-conjugating enzyme E2Z [Homo sapiens]           59   6e-09
gi|4507793 ubiquitin-conjugating enzyme E2N [Homo sapiens]             57   1e-08
gi|33149322 ubiquitin-conjugating enzyme E2D 3 isoform 2 [Homo s...    57   1e-08
gi|33149320 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo s...    57   1e-08
gi|33149318 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo s...    57   1e-08
gi|33149316 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo s...    57   1e-08
gi|33149314 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo s...    57   1e-08
gi|33149312 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo s...    57   1e-08
gi|33149310 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo s...    57   1e-08
gi|4507777 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo sa...    57   1e-08
gi|4507773 ubiquitin-conjugating enzyme E2D 1 [Homo sapiens]           57   2e-08
gi|4507775 ubiquitin-conjugating enzyme E2D 2 isoform 1 [Homo sa...    57   2e-08
gi|7661808 ubiquitin-conjugating enzyme E2T [Homo sapiens]             56   3e-08
gi|33359691 ubiquitin-conjugating enzyme E2E 1 isoform 2 [Homo s...    55   5e-08
gi|33149324 ubiquitin-conjugating enzyme E2D 3 isoform 3 [Homo s...    55   9e-08
gi|33188456 ubiquitin-conjugating enzyme E2D 2 isoform 2 [Homo s...    53   3e-07
gi|22212943 ubiquitin-conjugating enzyme UBC3B [Homo sapiens]          50   2e-06
gi|16357477 ubiquitin-conjugating enzyme Cdc34 [Homo sapiens]          50   2e-06

>gi|37577126 ubiquitin conjugating enzyme E2, J2 isoform 1 [Homo
           sapiens]
          Length = 275

 Score =  567 bits (1460), Expect = e-162
 Identities = 275/275 (100%), Positives = 275/275 (100%)

Query: 1   MSSTSSKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYR 60
           MSSTSSKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYR
Sbjct: 1   MSSTSSKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYR 60

Query: 61  HYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDT 120
           HYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDT
Sbjct: 61  HYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDT 120

Query: 121 WNPAWSVSTILTGLLSFMVEKGPTLGSIETSDFTKRQLAVQSLAFNLKDKVFCELFPEVV 180
           WNPAWSVSTILTGLLSFMVEKGPTLGSIETSDFTKRQLAVQSLAFNLKDKVFCELFPEVV
Sbjct: 121 WNPAWSVSTILTGLLSFMVEKGPTLGSIETSDFTKRQLAVQSLAFNLKDKVFCELFPEVV 180

Query: 181 EEIKQKQKAQDELSSRPQTLPLPDVVPDGETHLVQNGIQLLNGHAPGAVPNLAGLQQANR 240
           EEIKQKQKAQDELSSRPQTLPLPDVVPDGETHLVQNGIQLLNGHAPGAVPNLAGLQQANR
Sbjct: 181 EEIKQKQKAQDELSSRPQTLPLPDVVPDGETHLVQNGIQLLNGHAPGAVPNLAGLQQANR 240

Query: 241 HHGLLGGALANLFVIVGFAAFAYTVKYVLRSIAQE 275
           HHGLLGGALANLFVIVGFAAFAYTVKYVLRSIAQE
Sbjct: 241 HHGLLGGALANLFVIVGFAAFAYTVKYVLRSIAQE 275


>gi|37577124 ubiquitin conjugating enzyme E2, J2 isoform 2 [Homo
           sapiens]
          Length = 259

 Score =  521 bits (1343), Expect = e-148
 Identities = 259/275 (94%), Positives = 259/275 (94%), Gaps = 16/275 (5%)

Query: 1   MSSTSSKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYR 60
           MSSTSSKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEW                
Sbjct: 1   MSSTSSKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEW---------------- 44

Query: 61  HYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDT 120
           HYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDT
Sbjct: 45  HYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDT 104

Query: 121 WNPAWSVSTILTGLLSFMVEKGPTLGSIETSDFTKRQLAVQSLAFNLKDKVFCELFPEVV 180
           WNPAWSVSTILTGLLSFMVEKGPTLGSIETSDFTKRQLAVQSLAFNLKDKVFCELFPEVV
Sbjct: 105 WNPAWSVSTILTGLLSFMVEKGPTLGSIETSDFTKRQLAVQSLAFNLKDKVFCELFPEVV 164

Query: 181 EEIKQKQKAQDELSSRPQTLPLPDVVPDGETHLVQNGIQLLNGHAPGAVPNLAGLQQANR 240
           EEIKQKQKAQDELSSRPQTLPLPDVVPDGETHLVQNGIQLLNGHAPGAVPNLAGLQQANR
Sbjct: 165 EEIKQKQKAQDELSSRPQTLPLPDVVPDGETHLVQNGIQLLNGHAPGAVPNLAGLQQANR 224

Query: 241 HHGLLGGALANLFVIVGFAAFAYTVKYVLRSIAQE 275
           HHGLLGGALANLFVIVGFAAFAYTVKYVLRSIAQE
Sbjct: 225 HHGLLGGALANLFVIVGFAAFAYTVKYVLRSIAQE 259


>gi|37577132 ubiquitin conjugating enzyme E2, J2 isoform 3 [Homo
           sapiens]
          Length = 207

 Score =  425 bits (1093), Expect = e-119
 Identities = 207/207 (100%), Positives = 207/207 (100%)

Query: 69  MTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDTWNPAWSVS 128
           MTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDTWNPAWSVS
Sbjct: 1   MTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDTWNPAWSVS 60

Query: 129 TILTGLLSFMVEKGPTLGSIETSDFTKRQLAVQSLAFNLKDKVFCELFPEVVEEIKQKQK 188
           TILTGLLSFMVEKGPTLGSIETSDFTKRQLAVQSLAFNLKDKVFCELFPEVVEEIKQKQK
Sbjct: 61  TILTGLLSFMVEKGPTLGSIETSDFTKRQLAVQSLAFNLKDKVFCELFPEVVEEIKQKQK 120

Query: 189 AQDELSSRPQTLPLPDVVPDGETHLVQNGIQLLNGHAPGAVPNLAGLQQANRHHGLLGGA 248
           AQDELSSRPQTLPLPDVVPDGETHLVQNGIQLLNGHAPGAVPNLAGLQQANRHHGLLGGA
Sbjct: 121 AQDELSSRPQTLPLPDVVPDGETHLVQNGIQLLNGHAPGAVPNLAGLQQANRHHGLLGGA 180

Query: 249 LANLFVIVGFAAFAYTVKYVLRSIAQE 275
           LANLFVIVGFAAFAYTVKYVLRSIAQE
Sbjct: 181 LANLFVIVGFAAFAYTVKYVLRSIAQE 207


>gi|37577130 ubiquitin conjugating enzyme E2, J2 isoform 3 [Homo
           sapiens]
          Length = 207

 Score =  425 bits (1093), Expect = e-119
 Identities = 207/207 (100%), Positives = 207/207 (100%)

Query: 69  MTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDTWNPAWSVS 128
           MTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDTWNPAWSVS
Sbjct: 1   MTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDTWNPAWSVS 60

Query: 129 TILTGLLSFMVEKGPTLGSIETSDFTKRQLAVQSLAFNLKDKVFCELFPEVVEEIKQKQK 188
           TILTGLLSFMVEKGPTLGSIETSDFTKRQLAVQSLAFNLKDKVFCELFPEVVEEIKQKQK
Sbjct: 61  TILTGLLSFMVEKGPTLGSIETSDFTKRQLAVQSLAFNLKDKVFCELFPEVVEEIKQKQK 120

Query: 189 AQDELSSRPQTLPLPDVVPDGETHLVQNGIQLLNGHAPGAVPNLAGLQQANRHHGLLGGA 248
           AQDELSSRPQTLPLPDVVPDGETHLVQNGIQLLNGHAPGAVPNLAGLQQANRHHGLLGGA
Sbjct: 121 AQDELSSRPQTLPLPDVVPDGETHLVQNGIQLLNGHAPGAVPNLAGLQQANRHHGLLGGA 180

Query: 249 LANLFVIVGFAAFAYTVKYVLRSIAQE 275
           LANLFVIVGFAAFAYTVKYVLRSIAQE
Sbjct: 181 LANLFVIVGFAAFAYTVKYVLRSIAQE 207


>gi|37577122 ubiquitin-conjugating enzyme E2, J1 [Homo sapiens]
          Length = 318

 Score =  123 bits (308), Expect = 2e-28
 Identities = 59/154 (38%), Positives = 91/154 (59%), Gaps = 18/154 (11%)

Query: 13  ATQRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYRHYVVRGPEMTPY 72
           A +RL ++   +K DP  +  A+PL  N+ EW                H+ VRGP  + +
Sbjct: 11  AVKRLMKEAAELK-DPTDHYHAQPLEDNLFEW----------------HFTVRGPPDSDF 53

Query: 73  EGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDTWNPAWSVSTILT 132
           +GG YHG+++ P E+P KPPSI ++T NGRF+   ++CLSI+  HP+TW P+WS+ T L 
Sbjct: 54  DGGVYHGRIVLPPEYPMKPPSIILLTANGRFEVGKKICLSISGHHPETWQPSWSIRTALL 113

Query: 133 GLLSFMVEKGP-TLGSIETSDFTKRQLAVQSLAF 165
            ++ FM  KG   +GS++ +   +R LA +S  F
Sbjct: 114 AIIGFMPTKGEGAIGSLDYTPEERRALAKKSQDF 147


>gi|4507779 ubiquitin-conjugating enzyme E2E 1 isoform 1 [Homo
           sapiens]
          Length = 193

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 45/161 (27%), Positives = 73/161 (45%), Gaps = 24/161 (14%)

Query: 1   MSSTSSKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYR 60
           +S + + +  +T+ +R++++   I  DP P   A P   NI EW                
Sbjct: 36  VSMSKNSKLLSTSAKRIQKELADITLDPPPNCSAGPKGDNIYEW---------------- 79

Query: 61  HYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTR--LCLSITDFHP 118
              + GP  + YEGG +   + F  E+PFKPP +   T       N++  +CL   D   
Sbjct: 80  RSTILGPPGSVYEGGVFFLDITFTPEYPFKPPKVTFRTRIYHCNINSQGVICL---DILK 136

Query: 119 DTWNPAWSVSTILTGLLSFMVE---KGPTLGSIETSDFTKR 156
           D W+PA ++S +L  + S + +     P +GSI T   T R
Sbjct: 137 DNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYMTNR 177


>gi|4507771 ubiquitin-conjugating enzyme E2B [Homo sapiens]
          Length = 152

 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 39/135 (28%), Positives = 68/135 (50%), Gaps = 21/135 (15%)

Query: 11  TTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYRHYVVRGPEMT 70
           T A +RL +D+ R+++DP   +   P  +NI++W                + V+ GPE T
Sbjct: 3   TPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQW----------------NAVIFGPEGT 46

Query: 71  PYEGGYYHGKLIFPREFPFKPPSIYMITP--NGRFKCNTRLCLSITDFHPDTWNPAWSVS 128
           P+E G +   + F  E+P KPP++  ++   +     +  +CL I     + W+P + VS
Sbjct: 47  PFEDGTFKLVIEFSEEYPNKPPTVRFLSKMFHPNVYADGSICLDILQ---NRWSPTYDVS 103

Query: 129 TILTGLLSFMVEKGP 143
           +ILT + S + E  P
Sbjct: 104 SILTSIQSLLDEPNP 118


>gi|22749327 ubiquitin-conjugating enzyme E2E 2 [Homo sapiens]
          Length = 201

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 47/159 (29%), Positives = 72/159 (45%), Gaps = 26/159 (16%)

Query: 5   SSKRAP--TTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYRHY 62
           SSK A   +T+ +R++++   I  DP P   A P   NI EW                  
Sbjct: 46  SSKTAAKLSTSAKRIQKELAEITLDPPPNCSAGPKGDNIYEW----------------RS 89

Query: 63  VVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTR--LCLSITDFHPDT 120
            + GP  + YEGG +   + F  ++PFKPP +   T       N++  +CL   D   D 
Sbjct: 90  TILGPPGSVYEGGVFFLDITFSPDYPFKPPKVTFRTRIYHCNINSQGVICL---DILKDN 146

Query: 121 WNPAWSVSTILTGLLSFMVE---KGPTLGSIETSDFTKR 156
           W+PA ++S +L  + S + +     P +GSI T   T R
Sbjct: 147 WSPALTISKVLLSICSLLTDCNPADPLVGSIATQYMTNR 185


>gi|33359694 ubiquitin-conjugating enzyme E2E 3 [Homo sapiens]
          Length = 207

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 46/160 (28%), Positives = 73/160 (45%), Gaps = 26/160 (16%)

Query: 2   SSTSSKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYRH 61
           S T++K +  T+ +R++++   I  DP P   A P   NI EW                 
Sbjct: 53  SKTTAKLS--TSAKRIQKELAEITLDPPPNCSAGPKGDNIYEW----------------R 94

Query: 62  YVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTR--LCLSITDFHPD 119
             + GP  + YEGG +   + F  ++PFKPP +   T       N++  +CL   D   D
Sbjct: 95  STILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICL---DILKD 151

Query: 120 TWNPAWSVSTILTGLLSFMVE---KGPTLGSIETSDFTKR 156
            W+PA ++S +L  + S + +     P +GSI T   T R
Sbjct: 152 NWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLTNR 191


>gi|5454146 ubiquitin-conjugating enzyme E2E 3 [Homo sapiens]
          Length = 207

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 46/160 (28%), Positives = 73/160 (45%), Gaps = 26/160 (16%)

Query: 2   SSTSSKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYRH 61
           S T++K +  T+ +R++++   I  DP P   A P   NI EW                 
Sbjct: 53  SKTTAKLS--TSAKRIQKELAEITLDPPPNCSAGPKGDNIYEW----------------R 94

Query: 62  YVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTR--LCLSITDFHPD 119
             + GP  + YEGG +   + F  ++PFKPP +   T       N++  +CL   D   D
Sbjct: 95  STILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICL---DILKD 151

Query: 120 TWNPAWSVSTILTGLLSFMVE---KGPTLGSIETSDFTKR 156
            W+PA ++S +L  + S + +     P +GSI T   T R
Sbjct: 152 NWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLTNR 191


>gi|32967280 ubiquitin-conjugating enzyme E2A isoform 1 [Homo
           sapiens]
          Length = 152

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 39/135 (28%), Positives = 67/135 (49%), Gaps = 21/135 (15%)

Query: 11  TTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYRHYVVRGPEMT 70
           T A +RL +D+ R+++DP   +   P  +NI+ W                + V+ GPE T
Sbjct: 3   TPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVW----------------NAVIFGPEGT 46

Query: 71  PYEGGYYHGKLIFPREFPFKPPSIYMITP--NGRFKCNTRLCLSITDFHPDTWNPAWSVS 128
           P+E G +   + F  E+P KPP++  ++   +     +  +CL I     + W+P + VS
Sbjct: 47  PFEDGTFKLTIEFTEEYPNKPPTVRFVSKMFHPNVYADGSICLDILQ---NRWSPTYDVS 103

Query: 129 TILTGLLSFMVEKGP 143
           +ILT + S + E  P
Sbjct: 104 SILTSIQSLLDEPNP 118


>gi|8393719 ubiquitin-conjugating enzyme E2D 4 (putative) [Homo
           sapiens]
          Length = 147

 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 33/133 (24%), Positives = 60/133 (45%), Gaps = 21/133 (15%)

Query: 13  ATQRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYRHYVVRGPEMTPY 72
           A +R++++   +++DP     A P+  ++  W                   + GP  +PY
Sbjct: 2   ALKRIQKELTDLQRDPPAQCSAGPVGDDLFHW----------------QATIMGPNDSPY 45

Query: 73  EGGYYHGKLIFPREFPFKPPSIYMITP--NGRFKCNTRLCLSITDFHPDTWNPAWSVSTI 130
           +GG +   + FP ++PFKPP +   T   +     N  +CL   D     W+PA +VS +
Sbjct: 46  QGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICL---DILRSQWSPALTVSKV 102

Query: 131 LTGLLSFMVEKGP 143
           L  + S + +  P
Sbjct: 103 LLSICSLLCDPNP 115


>gi|150417999 ubiquitin-conjugating enzyme E2Z [Homo sapiens]
          Length = 354

 Score = 58.5 bits (140), Expect = 6e-09
 Identities = 40/147 (27%), Positives = 66/147 (44%), Gaps = 24/147 (16%)

Query: 2   SSTSSKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYRH 61
           S    +R       R+K+D + I K+P P +   P   ++ +                 H
Sbjct: 89  SDWDGERTAPQCLLRIKRDIMSIYKEPPPGMFVVPDTVDMTKI----------------H 132

Query: 62  YVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITP-------NGRFKCNTRLCLSIT 114
            ++ GP  TPYEGG++      P ++P  PP + ++T        N  F  N ++CLSI 
Sbjct: 133 ALITGPFDTPYEGGFFLFVFRCPPDYPIHPPRVKLMTTGNNTVRFNPNFYRNGKVCLSIL 192

Query: 115 -DFHPDTWNPAWSVSTILTGLLSFMVE 140
             +    W+PA S+S++L  + S M E
Sbjct: 193 GTWTGPAWSPAQSISSVLISIQSLMTE 219


>gi|4507793 ubiquitin-conjugating enzyme E2N [Homo sapiens]
          Length = 152

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 37/131 (28%), Positives = 60/131 (45%), Gaps = 21/131 (16%)

Query: 15  QRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYRHYVVRGPEMTPYEG 74
           +R+ ++  R+  +PVP I AEP  SN                  Y H V+ GP+ +P+EG
Sbjct: 6   RRIIKETQRLLAEPVPGIKAEPDESNAR----------------YFHVVIAGPQDSPFEG 49

Query: 75  GYYHGKLIFPREFPFKPPSIYMITP--NGRFKCNTRLCLSITDFHPDTWNPAWSVSTILT 132
           G +  +L  P E+P   P +  +T   +       R+CL   D   D W+PA  + T+L 
Sbjct: 50  GTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICL---DILKDKWSPALQIRTVLL 106

Query: 133 GLLSFMVEKGP 143
            + + +    P
Sbjct: 107 SIQALLSAPNP 117


>gi|33149322 ubiquitin-conjugating enzyme E2D 3 isoform 2 [Homo
           sapiens]
          Length = 148

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 34/135 (25%), Positives = 59/135 (43%), Gaps = 25/135 (18%)

Query: 13  ATQRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYRHYVVRGPEMTPY 72
           A +R+ ++   + +DP     A P+  ++  W                   + GP  +PY
Sbjct: 2   ALKRINKELSDLARDPPAQCSAGPVGDDMFHW----------------QATIMGPNDSPY 45

Query: 73  EGGYYHGKLIFPREFPFKPPSIYMIT----PNGRFKCNTRLCLSITDFHPDTWNPAWSVS 128
           +GG +   + FP ++PFKPP +   T    PN     N  +CL   D     W+PA ++S
Sbjct: 46  QGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPN--INSNGSICL---DILRSQWSPALTIS 100

Query: 129 TILTGLLSFMVEKGP 143
            +L  + S + +  P
Sbjct: 101 KVLLSICSLLCDPNP 115


>gi|33149320 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
           sapiens]
          Length = 147

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 34/135 (25%), Positives = 59/135 (43%), Gaps = 25/135 (18%)

Query: 13  ATQRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYRHYVVRGPEMTPY 72
           A +R+ ++   + +DP     A P+  ++  W                   + GP  +PY
Sbjct: 2   ALKRINKELSDLARDPPAQCSAGPVGDDMFHW----------------QATIMGPNDSPY 45

Query: 73  EGGYYHGKLIFPREFPFKPPSIYMIT----PNGRFKCNTRLCLSITDFHPDTWNPAWSVS 128
           +GG +   + FP ++PFKPP +   T    PN     N  +CL   D     W+PA ++S
Sbjct: 46  QGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPN--INSNGSICL---DILRSQWSPALTIS 100

Query: 129 TILTGLLSFMVEKGP 143
            +L  + S + +  P
Sbjct: 101 KVLLSICSLLCDPNP 115


>gi|33149318 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
           sapiens]
          Length = 147

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 34/135 (25%), Positives = 59/135 (43%), Gaps = 25/135 (18%)

Query: 13  ATQRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYRHYVVRGPEMTPY 72
           A +R+ ++   + +DP     A P+  ++  W                   + GP  +PY
Sbjct: 2   ALKRINKELSDLARDPPAQCSAGPVGDDMFHW----------------QATIMGPNDSPY 45

Query: 73  EGGYYHGKLIFPREFPFKPPSIYMIT----PNGRFKCNTRLCLSITDFHPDTWNPAWSVS 128
           +GG +   + FP ++PFKPP +   T    PN     N  +CL   D     W+PA ++S
Sbjct: 46  QGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPN--INSNGSICL---DILRSQWSPALTIS 100

Query: 129 TILTGLLSFMVEKGP 143
            +L  + S + +  P
Sbjct: 101 KVLLSICSLLCDPNP 115


>gi|33149316 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
           sapiens]
          Length = 147

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 34/135 (25%), Positives = 59/135 (43%), Gaps = 25/135 (18%)

Query: 13  ATQRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYRHYVVRGPEMTPY 72
           A +R+ ++   + +DP     A P+  ++  W                   + GP  +PY
Sbjct: 2   ALKRINKELSDLARDPPAQCSAGPVGDDMFHW----------------QATIMGPNDSPY 45

Query: 73  EGGYYHGKLIFPREFPFKPPSIYMIT----PNGRFKCNTRLCLSITDFHPDTWNPAWSVS 128
           +GG +   + FP ++PFKPP +   T    PN     N  +CL   D     W+PA ++S
Sbjct: 46  QGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPN--INSNGSICL---DILRSQWSPALTIS 100

Query: 129 TILTGLLSFMVEKGP 143
            +L  + S + +  P
Sbjct: 101 KVLLSICSLLCDPNP 115


>gi|33149314 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
           sapiens]
          Length = 147

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 34/135 (25%), Positives = 59/135 (43%), Gaps = 25/135 (18%)

Query: 13  ATQRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYRHYVVRGPEMTPY 72
           A +R+ ++   + +DP     A P+  ++  W                   + GP  +PY
Sbjct: 2   ALKRINKELSDLARDPPAQCSAGPVGDDMFHW----------------QATIMGPNDSPY 45

Query: 73  EGGYYHGKLIFPREFPFKPPSIYMIT----PNGRFKCNTRLCLSITDFHPDTWNPAWSVS 128
           +GG +   + FP ++PFKPP +   T    PN     N  +CL   D     W+PA ++S
Sbjct: 46  QGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPN--INSNGSICL---DILRSQWSPALTIS 100

Query: 129 TILTGLLSFMVEKGP 143
            +L  + S + +  P
Sbjct: 101 KVLLSICSLLCDPNP 115


>gi|33149312 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
           sapiens]
          Length = 147

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 34/135 (25%), Positives = 59/135 (43%), Gaps = 25/135 (18%)

Query: 13  ATQRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYRHYVVRGPEMTPY 72
           A +R+ ++   + +DP     A P+  ++  W                   + GP  +PY
Sbjct: 2   ALKRINKELSDLARDPPAQCSAGPVGDDMFHW----------------QATIMGPNDSPY 45

Query: 73  EGGYYHGKLIFPREFPFKPPSIYMIT----PNGRFKCNTRLCLSITDFHPDTWNPAWSVS 128
           +GG +   + FP ++PFKPP +   T    PN     N  +CL   D     W+PA ++S
Sbjct: 46  QGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPN--INSNGSICL---DILRSQWSPALTIS 100

Query: 129 TILTGLLSFMVEKGP 143
            +L  + S + +  P
Sbjct: 101 KVLLSICSLLCDPNP 115


>gi|33149310 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
           sapiens]
          Length = 147

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 34/135 (25%), Positives = 59/135 (43%), Gaps = 25/135 (18%)

Query: 13  ATQRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYRHYVVRGPEMTPY 72
           A +R+ ++   + +DP     A P+  ++  W                   + GP  +PY
Sbjct: 2   ALKRINKELSDLARDPPAQCSAGPVGDDMFHW----------------QATIMGPNDSPY 45

Query: 73  EGGYYHGKLIFPREFPFKPPSIYMIT----PNGRFKCNTRLCLSITDFHPDTWNPAWSVS 128
           +GG +   + FP ++PFKPP +   T    PN     N  +CL   D     W+PA ++S
Sbjct: 46  QGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPN--INSNGSICL---DILRSQWSPALTIS 100

Query: 129 TILTGLLSFMVEKGP 143
            +L  + S + +  P
Sbjct: 101 KVLLSICSLLCDPNP 115


>gi|4507777 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
           sapiens]
          Length = 147

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 34/135 (25%), Positives = 59/135 (43%), Gaps = 25/135 (18%)

Query: 13  ATQRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYRHYVVRGPEMTPY 72
           A +R+ ++   + +DP     A P+  ++  W                   + GP  +PY
Sbjct: 2   ALKRINKELSDLARDPPAQCSAGPVGDDMFHW----------------QATIMGPNDSPY 45

Query: 73  EGGYYHGKLIFPREFPFKPPSIYMIT----PNGRFKCNTRLCLSITDFHPDTWNPAWSVS 128
           +GG +   + FP ++PFKPP +   T    PN     N  +CL   D     W+PA ++S
Sbjct: 46  QGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPN--INSNGSICL---DILRSQWSPALTIS 100

Query: 129 TILTGLLSFMVEKGP 143
            +L  + S + +  P
Sbjct: 101 KVLLSICSLLCDPNP 115


>gi|4507773 ubiquitin-conjugating enzyme E2D 1 [Homo sapiens]
          Length = 147

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 33/133 (24%), Positives = 60/133 (45%), Gaps = 21/133 (15%)

Query: 13  ATQRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYRHYVVRGPEMTPY 72
           A +R++++   +++DP  +  A P+  ++  W                   + GP  + Y
Sbjct: 2   ALKRIQKELSDLQRDPPAHCSAGPVGDDLFHW----------------QATIMGPPDSAY 45

Query: 73  EGGYYHGKLIFPREFPFKPPSIYMITP--NGRFKCNTRLCLSITDFHPDTWNPAWSVSTI 130
           +GG +   + FP ++PFKPP I   T   +     N  +CL   D     W+PA +VS +
Sbjct: 46  QGGVFFLTVHFPTDYPFKPPKIAFTTKIYHPNINSNGSICL---DILRSQWSPALTVSKV 102

Query: 131 LTGLLSFMVEKGP 143
           L  + S + +  P
Sbjct: 103 LLSICSLLCDPNP 115


>gi|4507775 ubiquitin-conjugating enzyme E2D 2 isoform 1 [Homo
           sapiens]
          Length = 147

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 34/135 (25%), Positives = 59/135 (43%), Gaps = 25/135 (18%)

Query: 13  ATQRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYRHYVVRGPEMTPY 72
           A +R+ ++   + +DP     A P+  ++  W                   + GP  +PY
Sbjct: 2   ALKRIHKELNDLARDPPAQCSAGPVGDDMFHW----------------QATIMGPNDSPY 45

Query: 73  EGGYYHGKLIFPREFPFKPPSIYMIT----PNGRFKCNTRLCLSITDFHPDTWNPAWSVS 128
           +GG +   + FP ++PFKPP +   T    PN     N  +CL   D     W+PA ++S
Sbjct: 46  QGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPN--INSNGSICL---DILRSQWSPALTIS 100

Query: 129 TILTGLLSFMVEKGP 143
            +L  + S + +  P
Sbjct: 101 KVLLSICSLLCDPNP 115


>gi|7661808 ubiquitin-conjugating enzyme E2T [Homo sapiens]
          Length = 197

 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 39/134 (29%), Positives = 62/134 (46%), Gaps = 16/134 (11%)

Query: 64  VRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITP--NGRFKCNTRLCLSITDFHP-DT 120
           + G   TPYE G +  ++I P  +PF+PP I  +TP  +       R+CL +    P   
Sbjct: 38  ILGGANTPYEKGVFKLEVIIPERYPFEPPQIRFLTPIYHPNIDSAGRICLDVLKLPPKGA 97

Query: 121 WNPAWSVSTILTGLLSFMVEKGP--TLGSIETSDFTKRQLAVQSLAFNLKDKVFCELFPE 178
           W P+ +++T+LT +   M E  P   L +  +S+F   + A    A    +K        
Sbjct: 98  WRPSLNIATVLTSIQLLMSEPNPDDPLMADISSEFKYNKPAFLKNARQWTEK-------- 149

Query: 179 VVEEIKQKQKAQDE 192
                +QKQKA +E
Sbjct: 150 ---HARQKQKADEE 160


>gi|33359691 ubiquitin-conjugating enzyme E2E 1 isoform 2 [Homo
           sapiens]
          Length = 176

 Score = 55.5 bits (132), Expect = 5e-08
 Identities = 44/164 (26%), Positives = 69/164 (42%), Gaps = 28/164 (17%)

Query: 2   SSTSSKRAPTTATQRLKQDYLRIKKDP----VPYICAEPLPSNILEWFKRFSWLSLLSSW 57
           SS++ +    T T + K+  + + K+          A P   NI EW             
Sbjct: 16  SSSNQQTEKETNTPKKKESKVSMSKNSKLLSTSAKSAGPKGDNIYEW------------- 62

Query: 58  DYRHYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTR--LCLSITD 115
                 + GP  + YEGG +   + F  E+PFKPP +   T       N++  +CL   D
Sbjct: 63  ---RSTILGPPGSVYEGGVFFLDITFTPEYPFKPPKVTFRTRIYHCNINSQGVICL---D 116

Query: 116 FHPDTWNPAWSVSTILTGLLSFMVE---KGPTLGSIETSDFTKR 156
              D W+PA ++S +L  + S + +     P +GSI T   T R
Sbjct: 117 ILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYMTNR 160


>gi|33149324 ubiquitin-conjugating enzyme E2D 3 isoform 3 [Homo
           sapiens]
          Length = 149

 Score = 54.7 bits (130), Expect = 9e-08
 Identities = 33/131 (25%), Positives = 56/131 (42%), Gaps = 25/131 (19%)

Query: 17  LKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYRHYVVRGPEMTPYEGGY 76
           L ++   + +DP     A P+  ++  W                   + GP  +PY+GG 
Sbjct: 8   LSKELSDLARDPPAQCSAGPVGDDMFHW----------------QATIMGPNDSPYQGGV 51

Query: 77  YHGKLIFPREFPFKPPSIYMIT----PNGRFKCNTRLCLSITDFHPDTWNPAWSVSTILT 132
           +   + FP ++PFKPP +   T    PN     N  +CL   D     W+PA ++S +L 
Sbjct: 52  FFLTIHFPTDYPFKPPKVAFTTRIYHPN--INSNGSICL---DILRSQWSPALTISKVLL 106

Query: 133 GLLSFMVEKGP 143
            + S + +  P
Sbjct: 107 SICSLLCDPNP 117


>gi|33188456 ubiquitin-conjugating enzyme E2D 2 isoform 2 [Homo
           sapiens]
          Length = 118

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 9/84 (10%)

Query: 64  VRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMIT----PNGRFKCNTRLCLSITDFHPD 119
           + GP  +PY+GG +   + FP ++PFKPP +   T    PN     N  +CL   D    
Sbjct: 8   IMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPN--INSNGSICL---DILRS 62

Query: 120 TWNPAWSVSTILTGLLSFMVEKGP 143
            W+PA ++S +L  + S + +  P
Sbjct: 63  QWSPALTISKVLLSICSLLCDPNP 86


>gi|22212943 ubiquitin-conjugating enzyme UBC3B [Homo sapiens]
          Length = 238

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 31/101 (30%), Positives = 49/101 (48%), Gaps = 19/101 (18%)

Query: 54  LSSWDYRHYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITP--NGRFKCNTRLCL 111
           L +W+     + GP  T YEGGY+   + FP ++P+ PP+   +T   +     N  +C+
Sbjct: 38  LYNWEV---AIFGPPNTLYEGGYFKAHIKFPIDYPYSPPTFRFLTKMWHPNIYENGDVCI 94

Query: 112 SITDFHP------------DTWNPAWSVSTILTGLLSFMVE 140
           SI   HP            + WNP  +V TIL  ++S + E
Sbjct: 95  SI--LHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNE 133


>gi|16357477 ubiquitin-conjugating enzyme Cdc34 [Homo sapiens]
          Length = 236

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 31/101 (30%), Positives = 49/101 (48%), Gaps = 19/101 (18%)

Query: 54  LSSWDYRHYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITP--NGRFKCNTRLCL 111
           L +W+     + GP  T YEGGY+  +L FP ++P+ PP+   +T   +        +C+
Sbjct: 38  LYNWEV---AIFGPPNTYYEGGYFKARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCI 94

Query: 112 SITDFHP------------DTWNPAWSVSTILTGLLSFMVE 140
           SI   HP            + WNP  +V TIL  ++S + E
Sbjct: 95  SI--LHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNE 133


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,491,960
Number of Sequences: 37866
Number of extensions: 549673
Number of successful extensions: 1480
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 1385
Number of HSP's gapped (non-prelim): 86
length of query: 275
length of database: 18,247,518
effective HSP length: 101
effective length of query: 174
effective length of database: 14,423,052
effective search space: 2509611048
effective search space used: 2509611048
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.