Guide to the Human Genome
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Name: MTHFD1L Sequence: fasta or formatted (978aa) NCBI GI: 36796743
Description:

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like

Referenced in:

Mitochondria
Vitamin Pathways, Coenzymes, and 1-Carbon Metabolism

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.6         84           3
 C cysteine            1.6         16           2
 D aspartate           5.4         53           2
 E glutamate           5.5         54           3
 F phenylalanine       3.0         29           2
 G glycine             9.0         88           9
 H histidine           2.0         20           1
 I isoleucine          6.4         63           2
 K lysine              5.8         57           2
 L leucine            10.7        105           2
 M methionine          1.6         16           1
 N asparagine          3.5         34           2
 P proline             5.4         53           2
 Q glutamine           4.9         48           2
 R arginine            5.6         55           2
 S serine              5.5         54           2
 T threonine           5.2         51           2
 V valine              8.2         80           3
 W tryptophan          0.6          6           1
 Y tyrosine            1.2         12           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   methylenetetrahydrofolate dehydrogenase (NADP+ depen... 
MTHFD1                0.572   methylenetetrahydrofolate dehydrogenase 1 
MTHFD2L               0.029   methylenetetrahydrofolate dehydrogenase 2-like [Hom...
MTHFD2                0.025   methylenetetrahydrofolate dehydrogenase 2 precursor ...
C9orf150              0.009   hypothetical protein LOC286343 
LOC100292172          0.007   PREDICTED: hypothetical protein 
LOC100289763          0.007   PREDICTED: hypothetical protein XP_002347867 
LOC100289681          0.007   PREDICTED: hypothetical protein XP_002343623 
BPTF                  0.007   bromodomain PHD finger transcription factor isoform ...
BPTF                  0.007   bromodomain PHD finger transcription factor isoform ...
ZSWIM6                0.006   zinc finger, SWIM-type containing 6 
LOC728767             0.006   PREDICTED: hypothetical protein 
LOC728767             0.006   PREDICTED: hypothetical protein 
LMO2                  0.006   LIM domain only 2 isoform 1 
HNRNPUL2              0.006   heterogeneous nuclear ribonucleoprotein U-like 2 [H...
ANO8                  0.005   anoctamin 8 
GPC2                  0.005   glypican 2 
LOC100287499          0.005   PREDICTED: hypothetical protein 
LOC100287499          0.005   PREDICTED: hypothetical protein XP_002343643 
CASC3                 0.005   metastatic lymph node 51 
XYLT1                 0.005   xylosyltransferase I 
LOC100292082          0.005   PREDICTED: hypothetical protein XP_002345881 
LOC100292376          0.005   PREDICTED: hypothetical protein 
LOC100290709          0.005   PREDICTED: hypothetical protein XP_002346752 
LOC100290765          0.005   PREDICTED: hypothetical protein XP_002346483 
LOC100287864          0.005   PREDICTED: hypothetical protein XP_002342323 
SMAD6                 0.005   SMAD family member 6 isoform 1 
BAT2                  0.005   HLA-B associated transcript-2 
KIF3C                 0.005   kinesin family member 3C 
LOC100292058          0.005   PREDICTED: hypothetical protein XP_002344766 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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