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Search of human proteins with 35038601
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|35038601 spindle assembly abnormal protein 6 [Homo sapiens]
(657 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|35038601 spindle assembly abnormal protein 6 [Homo sapiens] 1283 0.0
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 86 1e-16
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 85 2e-16
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 84 5e-16
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 83 9e-16
gi|118498356 kinectin 1 isoform a [Homo sapiens] 83 9e-16
gi|118498368 kinectin 1 isoform c [Homo sapiens] 83 9e-16
gi|33620775 kinectin 1 isoform a [Homo sapiens] 83 9e-16
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 82 2e-15
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 82 2e-15
gi|156104908 myosin heavy chain 6 [Homo sapiens] 81 3e-15
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 80 6e-15
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 80 8e-15
gi|118498362 kinectin 1 isoform b [Homo sapiens] 80 8e-15
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 80 8e-15
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 79 1e-14
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 79 1e-14
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 79 1e-14
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 79 1e-14
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 79 2e-14
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 78 2e-14
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 78 2e-14
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 77 5e-14
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 77 5e-14
gi|71061468 centromere protein E [Homo sapiens] 77 5e-14
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 77 5e-14
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 77 7e-14
gi|219555661 intraflagellar transport 81-like isoform 1 [Homo sa... 77 7e-14
gi|32526901 intraflagellar transport 81-like isoform 1 [Homo sap... 77 7e-14
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 76 9e-14
>gi|35038601 spindle assembly abnormal protein 6 [Homo sapiens]
Length = 657
Score = 1283 bits (3321), Expect = 0.0
Identities = 657/657 (100%), Positives = 657/657 (100%)
Query: 1 MSQVLFHQLVPLQVKCKDCEERRVSIRMSIELQSVSNPVHRKDLVIRLTDDTDPFFLYNL 60
MSQVLFHQLVPLQVKCKDCEERRVSIRMSIELQSVSNPVHRKDLVIRLTDDTDPFFLYNL
Sbjct: 1 MSQVLFHQLVPLQVKCKDCEERRVSIRMSIELQSVSNPVHRKDLVIRLTDDTDPFFLYNL 60
Query: 61 VISEEDFQSLKFQQGLLVDFLAFPQKFIDLLQQCTQEHAKEIPRFLLQLVSPAAILDNSP 120
VISEEDFQSLKFQQGLLVDFLAFPQKFIDLLQQCTQEHAKEIPRFLLQLVSPAAILDNSP
Sbjct: 61 VISEEDFQSLKFQQGLLVDFLAFPQKFIDLLQQCTQEHAKEIPRFLLQLVSPAAILDNSP 120
Query: 121 AFLNVVETNPFKHLTHLSLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDF 180
AFLNVVETNPFKHLTHLSLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDF
Sbjct: 121 AFLNVVETNPFKHLTHLSLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDF 180
Query: 181 TRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLE 240
TRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLE
Sbjct: 181 TRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLE 240
Query: 241 ILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLR 300
ILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLR
Sbjct: 241 ILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLR 300
Query: 301 RENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGE 360
RENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGE
Sbjct: 301 RENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGE 360
Query: 361 KNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEE 420
KNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEE
Sbjct: 361 KNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEE 420
Query: 421 KLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNE 480
KLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNE
Sbjct: 421 KLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNE 480
Query: 481 NQLVRKQDVLGPSTTPPAHSSSNTIRSGISPNLNVVDGRLTYPTCGIGYPVSSAFAFQNT 540
NQLVRKQDVLGPSTTPPAHSSSNTIRSGISPNLNVVDGRLTYPTCGIGYPVSSAFAFQNT
Sbjct: 481 NQLVRKQDVLGPSTTPPAHSSSNTIRSGISPNLNVVDGRLTYPTCGIGYPVSSAFAFQNT 540
Query: 541 FPHSISAKNTSHPGSGTKVQFNLQFTKPNASLGDVQSGATISMPCSTDKENGENVGLESK 600
FPHSISAKNTSHPGSGTKVQFNLQFTKPNASLGDVQSGATISMPCSTDKENGENVGLESK
Sbjct: 541 FPHSISAKNTSHPGSGTKVQFNLQFTKPNASLGDVQSGATISMPCSTDKENGENVGLESK 600
Query: 601 YLKKREDSIPLRGLSQNLFSNSDHQRDGTLGALHTSSKPTALPSASSAYFPGQLPNS 657
YLKKREDSIPLRGLSQNLFSNSDHQRDGTLGALHTSSKPTALPSASSAYFPGQLPNS
Sbjct: 601 YLKKREDSIPLRGLSQNLFSNSDHQRDGTLGALHTSSKPTALPSASSAYFPGQLPNS 657
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 85.9 bits (211), Expect = 1e-16
Identities = 88/358 (24%), Positives = 165/358 (46%), Gaps = 34/358 (9%)
Query: 158 KCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNE 217
K KE K L +++ K+ +K+L ++K+ +L+ E S L + NE
Sbjct: 892 KTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNE 951
Query: 218 KEKA-LQAQV-QYQQQHEQQKKDLEILHQQ------NIHQLQNRLSE-LEAANKDLTERK 268
KE+ LQ + + +Q EQ+KK +E L + +L+N+L + L A ++L K
Sbjct: 952 KEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEK 1011
Query: 269 YK----------GDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVEC-------H 311
K T ++L++ G E EL T+Q++ S+ + S +
Sbjct: 1012 EKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIG 1071
Query: 312 EKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEA 371
+ K + +L+T A LEQ+ K+Q + +A IQ++K + E+ + +L ++E
Sbjct: 1072 NQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEE 1131
Query: 372 TIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKL----QKEQK 427
E+ K NE +K + + + LK + IQQ+ L K + L ++E++
Sbjct: 1132 IKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKR 1191
Query: 428 ELQDVGQSLRIKEQEVCK----LQEQLEATVKKLEESKQLLKNNEKLITWLNKELNEN 481
Q + ++ +E+E+ K + +L + +K+ E + + NE +T LNEN
Sbjct: 1192 NQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNEN 1249
Score = 84.3 bits (207), Expect = 3e-16
Identities = 84/355 (23%), Positives = 167/355 (47%), Gaps = 40/355 (11%)
Query: 161 KEEKLSLMQSLDDATKQLDFTRKTLAEKKQ----ELDKLRNEWASHTAALTNKHSQELTN 216
+EEK L Q + +++ + L + Q EL K++ E + L+ +L+
Sbjct: 806 EEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTV-KDKLSK 864
Query: 217 EKEKALQAQVQYQQQHEQQKK---DLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDS 273
+ ++ ++++++++ K DLE ++ HQLQ ++ K+L + K
Sbjct: 865 VSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKE 924
Query: 274 TIRELKAKLSGVEEE-------LQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQ--TKV 324
+LK +L+ ++E+ L++ ++E L+ + L +K+K + LQ K+
Sbjct: 925 ASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKI 984
Query: 325 AVLEQ-EIKDK-DQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLK 382
AVL++ E+++K Q + + + +E+ VL+ N EK+Q +L++ +ELL
Sbjct: 985 AVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLA 1044
Query: 383 ANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLL--------------AEKEEKLQKEQKE 428
+ +K ++ L L Q KL+ A+KE++LQ+ K
Sbjct: 1045 TRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKA 1104
Query: 429 LQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQL 483
LQD+ + +KE+E+ + KL E +++ EK IT LN+EL ++L
Sbjct: 1105 LQDIQKEKSLKEKELVNEK-------SKLAEIEEIKCRQEKEITKLNEELKSHKL 1152
Score = 75.5 bits (184), Expect = 1e-13
Identities = 80/320 (25%), Positives = 150/320 (46%), Gaps = 38/320 (11%)
Query: 190 QELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQ---KKDLEI-LHQQ 245
QEL KL+ S LT K+ Q LT K Q + +++H ++ KK+++ LHQ+
Sbjct: 288 QELQKLK----SSVNELTQKN-QTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQK 342
Query: 246 NI--HQLQNRLSELEAA-NKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRE 302
++ QLQ+RLS E + ++ E KG++T ++LK +LS VE + Q K E L+++
Sbjct: 343 DLDCQQLQSRLSASETSLHRIHVELSEKGEAT-QKLKEELSEVETKYQHLKAEFKQLQQQ 401
Query: 303 NSTLDVECHEKEKHVNQLQTKVAVLEQEI------------------KDKDQLVLRTKEA 344
+ + + +NQL +K+ E+++ DK+Q V +
Sbjct: 402 REEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLK 461
Query: 345 FDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLK 404
++EQ N + Q QL K + + A +++ Q DL+ ++ ++ K
Sbjct: 462 LSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDK 521
Query: 405 NTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVC---KLQEQLEATVKKLEESK 461
+ E LL + +E + +KE +D+ ++ E E +LQE+ +++ +
Sbjct: 522 DQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLT 581
Query: 462 QLLKNNEKLITWLNKELNEN 481
+ LKN + +K+ EN
Sbjct: 582 EKLKNQSE----SHKQAQEN 597
Score = 68.9 bits (167), Expect = 1e-11
Identities = 84/331 (25%), Positives = 152/331 (45%), Gaps = 54/331 (16%)
Query: 173 DATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNK--HSQELTNE----KEKALQAQV 226
D LD + L +K+QEL+K+ + TA L +K H +L + KEK L +
Sbjct: 664 DLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQ 723
Query: 227 QYQQQHEQQKK------DLEILHQQNIHQLQNRLS-----ELEAA--NKDLTERKYKGDS 273
+ ++ Q KK +++ +Q + LQ + EL A +K L K S
Sbjct: 724 KTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSS 783
Query: 274 TIRELKAK---LSGVEEELQRTKQEVLSLRRENSTLDVECH-EKEKHVNQLQTKVAVLEQ 329
T +L+ K L ++++L + ++E L+++ TL E + E+ N++QT V L++
Sbjct: 784 TRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQK 843
Query: 330 EIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKK 389
+K+ L+ D +L K+ ++K+ +E K N+ K
Sbjct: 844 VKMEKEALMTELSTVKD------------------KLSKVSDSLKNSKSEFEKENQKGKA 885
Query: 390 LQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQ 449
DL+ +LK+ + +Q E L KEQKEL+ +SL +++ +L+ +
Sbjct: 886 AILDLEKTC--KELKHQLQVQMENTL--------KEQKELK---KSLEKEKEASHQLKLE 932
Query: 450 LEATVKKLEESKQLLKNNEKLITWLNKELNE 480
L + ++L +++ LK NEK L +NE
Sbjct: 933 LNSMQEQLIQAQNTLKQNEKEEQQLQGNINE 963
Score = 67.8 bits (164), Expect = 3e-11
Identities = 73/337 (21%), Positives = 159/337 (47%), Gaps = 23/337 (6%)
Query: 161 KEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEK 220
K++K+ +++L +K+ +L EK++E + + A+ N+ ++ +E+
Sbjct: 521 KDQKIQNLEALLQKSKE----NISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQ 576
Query: 221 ALQAQVQYQQQHEQQKKDLEILHQQ------NIHQLQNRLSELEAA----NKDLTERKYK 270
Q + + Q E K+ E LH Q ++ Q+R+ LE + N L E K K
Sbjct: 577 VTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEK 636
Query: 271 GDSTIRELKAKLSGV-EEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQ 329
++KAK + E +T Q L+ T +K++ +N++ T++ +
Sbjct: 637 VSQLDIQIKAKTELLLSAEAAKTAQRA-DLQNHLDTAQNALQDKQQELNKITTQLDQVTA 695
Query: 330 EIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEAT---IKSLSAELLKANEI 386
+++DK + + + +E+ + LE+ E+ + Q+ KLEA +K+ + L+ +
Sbjct: 696 KLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQ 755
Query: 387 IKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKL 446
++L DL+ + +L + +++E +++ LQK+ + L+ + Q L +E+E L
Sbjct: 756 QRQLNTDLE--LRATELSKQLEMEKE-IVSSTRLDLQKKSEALESIKQKLTKQEEEKQIL 812
Query: 447 QEQLEATVKKLEESKQLLKNN-EKLITWLNKELNENQ 482
++ E ++ + + L N + +T L K E +
Sbjct: 813 KQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKE 849
Score = 66.2 bits (160), Expect = 9e-11
Identities = 70/332 (21%), Positives = 151/332 (45%), Gaps = 57/332 (17%)
Query: 161 KEEKLSLMQSLDDATKQLDFTRKTLAEK-KQELDKLRNEWASHTAALTNKHSQELTNEKE 219
K+E + + +D+ T + R+ +EK K E KL++++AS A ++ S+ +E
Sbjct: 227 KKELVQVQTLMDNMTLE----RERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQE 282
Query: 220 KALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELK 279
A+ + Q + +L++ ++EL N+ LTE K + +L+
Sbjct: 283 VAV--------------------YVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLE 322
Query: 280 AKLSGVEEELQRTKQEVLSLRRENSTL---DVECHEKEKHVNQLQTKVAVLEQEIKDKDQ 336
K + +E +S + +TL D++C + + ++ +T + + E+ +K +
Sbjct: 323 EKHN----------EESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGE 372
Query: 337 LVLRTKEAFDTIQ--------EQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIK 388
+ KE ++ E K + ++ EK Q L +L++ I L ++LL+ +
Sbjct: 373 ATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGL-QLQSEINQLHSKLLETERQLG 431
Query: 389 KLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQE 448
+ G +LK + EKL+ +KE+++ Q +L + + L+ K +LQ
Sbjct: 432 EAHG---------RLKEQRQLSSEKLM-DKEQQVADLQLKLSRLEEQLKEKVTNSTELQH 481
Query: 449 QLEATVKKLEESKQLLKNNEKLITWLNKELNE 480
QL+ T ++ +E + L ++ + +L +
Sbjct: 482 QLDKTKQQHQEQQALQQSTTAKLREAQNDLEQ 513
Score = 60.5 bits (145), Expect = 5e-09
Identities = 77/331 (23%), Positives = 137/331 (41%), Gaps = 41/331 (12%)
Query: 157 LKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRN--EWASHTAALTNKHSQEL 214
L +++ L Q + D L + E K+EL+K + + + L S EL
Sbjct: 78 LALKRDDVTLLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSSAEL 137
Query: 215 TNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSEL-----------EAANKD 263
++L+ Q++ Q K ++ L +Q QL ++++ EAA +
Sbjct: 138 -----QSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQK 192
Query: 264 ---LTERKYKGDSTIRELKAKL---SGVEEELQRTKQEV----------LSLRRENSTLD 307
LTE K + I++LK +L G+E+ K+ V L RE+ L
Sbjct: 193 VTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLK 252
Query: 308 VECHE-------KEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGE 360
EC + E ++QL++++A QE+ Q + + K + + + ++ L EN
Sbjct: 253 DECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLL 312
Query: 361 KNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEE 420
K + KLE S + + D + L +L T + L+EK E
Sbjct: 313 KKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGE 372
Query: 421 KLQKEQKELQDVGQSLRIKEQEVCKLQEQLE 451
QK ++EL +V + + E +LQ+Q E
Sbjct: 373 ATQKLKEELSEVETKYQHLKAEFKQLQQQRE 403
Score = 58.2 bits (139), Expect = 2e-08
Identities = 74/359 (20%), Positives = 154/359 (42%), Gaps = 40/359 (11%)
Query: 165 LSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQA 224
L + L +A +L R+ +EK + ++ + + L + +++TN E Q
Sbjct: 424 LETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQL 483
Query: 225 QVQYQQQHEQQ-------------KKDLE-ILHQ--------QNIHQL----QNRLSELE 258
QQ EQQ + DLE +L Q QN+ L + +S LE
Sbjct: 484 DKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLE 543
Query: 259 AANKDLTERKYKGD---STIRELKAKLSGVEEEL----QRTKQEVLSLRRENSTLDVECH 311
+DL + G+ + + +L+ K ++E++ ++ K + S ++ L +
Sbjct: 544 KEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQ 603
Query: 312 EKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQ-----KVVLEENGEKNQVQL 366
E++ H+ Q +V LE + + + + +KE + Q +++L K Q
Sbjct: 604 EQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKT-AQR 662
Query: 367 GKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQ 426
L+ + + L + + K+ L + KL+ K Q E L E +EK +
Sbjct: 663 ADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLE 722
Query: 427 KELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELN-ENQLV 484
++ +++ ++ E + +++ E ++ L++ +QL + E T L+K+L E ++V
Sbjct: 723 QKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIV 781
Score = 53.5 bits (127), Expect = 6e-07
Identities = 74/296 (25%), Positives = 137/296 (46%), Gaps = 47/296 (15%)
Query: 236 KKDLEILHQQNIHQLQNRLSELEAANKDLTER--KYKGDSTIRELKAKLSGV----EEEL 289
K+D L +Q + LQ L E + +++L + KY+G +++ +AK G+ EL
Sbjct: 81 KRDDVTLLRQEVQDLQASLKEEKWYSEELKKELEKYQG---LQQQEAKPDGLVTDSSAEL 137
Query: 290 QRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQ 349
Q +Q++ + EN + E+ QL T++A ++ + ++ L +EA
Sbjct: 138 QSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSL----REA----A 189
Query: 350 EQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEI-----IKKLQGDLKTLMGKLKLK 404
EQKV + +L K I+ L ELL+ I +KK ++TLM
Sbjct: 190 EQKVT------RLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLM------ 237
Query: 405 NTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLE---ESK 461
+ +T+++E+ + EKL+ E K+LQ S E + +L+ +L +++ +
Sbjct: 238 DNMTLERER----ESEKLKDECKKLQSQYAS---SEATISQLRSELAKGPQEVAVYVQEL 290
Query: 462 QLLKNNEKLITWLNKELNENQLVRKQDVLGPSTTPPAHSSSNTIRSGISPNLNVVD 517
Q LK++ +T N+ L EN L ++QD + H+ + + I L+ D
Sbjct: 291 QKLKSSVNELTQKNQTLTENLLKKEQDY---TKLEEKHNEESVSKKNIQATLHQKD 343
Score = 39.7 bits (91), Expect = 0.009
Identities = 47/188 (25%), Positives = 88/188 (46%), Gaps = 31/188 (16%)
Query: 162 EEKLSLM---QSLDDATKQLDFTRKTLAEK-KQELDKLRNEWASHTAALTNK-HSQELTN 216
++KL L SL A +Q ++ L ++ K+E ++L+ E+ A L ++ +E+
Sbjct: 1170 QQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGM 1229
Query: 217 EKEKALQAQVQYQ------------QQHEQQKKDLEILHQQNIHQLQNRLSELEAA---N 261
+K + +A++ Q ++ + ++ + L +Q L+ ++ LEA N
Sbjct: 1230 KKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQT-DDLRGEIAVLEATVQNN 1288
Query: 262 KD----LTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHV 317
+D L ER KG+ I +L+ K+ ++ +L T V L REN +L + KH
Sbjct: 1289 QDERRALLERCLKGEGEIEKLQTKVLELQRKLDNTTAAVQELGRENQSLQI------KHT 1342
Query: 318 NQLQTKVA 325
L K A
Sbjct: 1343 QALNRKWA 1350
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 84.7 bits (208), Expect = 2e-16
Identities = 108/500 (21%), Positives = 210/500 (42%), Gaps = 79/500 (15%)
Query: 8 QLVPLQVKCKDCEERRVSIRMSIELQSVSNPVHRKDLVIRLTDDTDPFFLYNLVISEEDF 67
QL LQ KD E+ + I+ L+ ++ V KD DF
Sbjct: 1497 QLRSLQADAKDLEQHK--IKQEEILKEINKIVAAKD---------------------SDF 1533
Query: 68 QSLKFQQGLLVDFLAFPQKFIDLLQQCTQEHAKEIPRFLLQLVSPAAILDNSPAFLNVVE 127
Q L ++ L + L QK I++ ++ H + + + L + A L+ + + +
Sbjct: 1534 QCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQ 1593
Query: 128 TNPF---KHLTHLS--LKLLPGNDVEIKKFLAGCLKCSKEE---KLSLMQSLDDATKQLD 179
+ L H L LL G+ V+ K L L+ + E K + ++ + ++L
Sbjct: 1594 QEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELS 1653
Query: 180 FTRKTL----AEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQ 235
F + L +E+K +L ++ QE+ E+E LQ ++ +H+ +
Sbjct: 1654 FQKGELNVQISERKTQLTLIK---------------QEIEKEEEN-LQVVLRQMSKHKTE 1697
Query: 236 KKDLEILHQQNIHQLQN-------RLSELEAANKDLTERKYKGDST---IRELKAKLSGV 285
K++ + Q H+LQ R+SELE + E K + ++ ++ K ++
Sbjct: 1698 LKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQ 1757
Query: 286 EEELQRTKQEVLSLRRENSTLD--VECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKE 343
++ L+R K+E+ + E+ L VEC KEK LQ K + E+++ +++
Sbjct: 1758 KQLLERDKREIERMTAESRALQSCVECLSKEKE--DLQEKCDIWEKKLAQTKRVL----- 1810
Query: 344 AFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKL 403
EEN + Q L KLE ++ L EL + N L D+ + +L+
Sbjct: 1811 ---------AAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQE 1861
Query: 404 KNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQL 463
K ++ LA ++ L +++L + + E +LQ+ + + E+ ++
Sbjct: 1862 KREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKE 1921
Query: 464 LKNNEKLITWLNKELNENQL 483
+ ++ + L E+ EN+L
Sbjct: 1922 EETKQQQLQVLQNEIEENKL 1941
Score = 63.9 bits (154), Expect = 4e-10
Identities = 75/353 (21%), Positives = 163/353 (46%), Gaps = 33/353 (9%)
Query: 150 KKFLAGCLKCSKEEKLSLMQSL---DDATKQLDFTRKTLAEKKQEL---DKLRNEWASH- 202
K F+ G ++ E L + +SL +D +++ KTL +++ EL D+L E S
Sbjct: 1391 KDFIDGNVESLMTE-LEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESEL 1449
Query: 203 --TAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAA 260
T T ++ T+ K LQ + ++ E++ ++ + N+ + +L L+A
Sbjct: 1450 SCTKEKTKNAVEKFTDAKRSLLQTESDAEEL-ERRAQETAV----NLVKADQQLRSLQAD 1504
Query: 261 NKDLTERKYKGDSTIRELKAKLSGVEEELQ--RTKQEVLSLRRENSTLDVECHEKEK--H 316
KDL + K K + ++E+ ++ + + Q K+E L+ + D+E E+ + H
Sbjct: 1505 AKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHH 1564
Query: 317 VNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSL 376
+ L+ +L+ + + ++L K + Q++ VL+ + +L L+ ++
Sbjct: 1565 LQVLKESEVLLQAKRAELEKL----KSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQA 1620
Query: 377 SAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSL 436
A+L +A + G+ + ++ ++ +E + E +Q +++ Q L
Sbjct: 1621 KADLQEALRL-----GETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQ-----L 1670
Query: 437 RIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQDV 489
+ +QE+ K +E L+ ++++ + K LKN ++ N EL +L Q V
Sbjct: 1671 TLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRV 1723
Score = 63.5 bits (153), Expect = 6e-10
Identities = 77/361 (21%), Positives = 157/361 (43%), Gaps = 66/361 (18%)
Query: 153 LAGCLKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQ 212
L C++C +EK +D ++ D K LA+ K+ L AA
Sbjct: 1778 LQSCVECLSKEK-------EDLQEKCDIWEKKLAQTKRVL-----------AAAEENSKM 1819
Query: 213 ELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGD 272
E +N ++ L + + QQ+ +Q +D LH +I +Q +L E A
Sbjct: 1820 EQSNLEKLELNVR-KLQQELDQLNRDKLSLHN-DISAMQQQLQEKREA------------ 1865
Query: 273 STIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQ------------- 319
+ L+ +L+ V++ L KQ++L + L E +K +++
Sbjct: 1866 --VNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEE 1923
Query: 320 -LQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQ-----------KVVLEENGEKNQVQLG 367
Q ++ VL+ EI++ +++ + F +Q++ KV L+E + + +L
Sbjct: 1924 TKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELT 1983
Query: 368 KLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQK 427
++ + + +++L A E ++ LQ + + L+ T++ Q ++ L+E+E++L ++
Sbjct: 1984 DQKSKLDQVLSKVLAAEERVRTLQEEERWCE---SLEKTLS-QTKRQLSEREQQLVEKSG 2039
Query: 428 ELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQ 487
EL + + + L+ Q KK E+ LK K+ +L +N L +KQ
Sbjct: 2040 ELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKI---QRSQLEKNLLEQKQ 2096
Query: 488 D 488
+
Sbjct: 2097 E 2097
Score = 62.4 bits (150), Expect = 1e-09
Identities = 98/412 (23%), Positives = 175/412 (42%), Gaps = 52/412 (12%)
Query: 138 SLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDA---TKQLDFTRKTLAEKKQELDK 194
SL+ L G V + + S EE L + L+ T++L + E+ + DK
Sbjct: 246 SLESLEGQPVTTQDRQEAFERFSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDK 305
Query: 195 LRNEWASHTAALTNKHSQELTNE--------KEKALQAQVQYQQQHEQQKKDLEILHQQN 246
L N+ A L + +EL ++ K+K ++ Q+Q+E +++
Sbjct: 306 L-NKSLKEEAMLQKQSCEELKSDLNTKNELLKQKTIELTRACQKQYELEQELAFYKIDAK 364
Query: 247 IHQLQNRLSELEAANKDLTERKYKGDSTI-RELKAKLSGVEEELQRTKQEVLS----LR- 300
L SE +K E Y G S R + A S + + Q + + + LR
Sbjct: 365 FEPLNYYPSEYAEIDKAPDESPYIGKSRYKRNMFATESYIIDSAQAVQIKKMEPDEQLRN 424
Query: 301 -----RENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVL 355
R ++ LD + +KEK ++ QT+++ L EI+ +Q +LR E F ++E
Sbjct: 425 DHMNLRGHTPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEE----- 479
Query: 356 EENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKN-TVTIQQEKL 414
+QL K+ K L + K+L G L+ L+ KL+ + + +Q EK
Sbjct: 480 -------AIQLKKISEAGKDL---------LYKQLSGRLQ-LVNKLRQEALDLELQMEKQ 522
Query: 415 LAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLE----ESKQLLKNNEKL 470
E K QKE K+LQ SL K+ + ++ Q ++L+ + +QL +++
Sbjct: 523 KQEIAGK-QKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEI 581
Query: 471 ITWLNKELNENQLVRKQDVLGPSTTPPA-HSSSNTIRSGISPNLNVVDGRLT 521
++ + KE E + + +Q G A + SG+ L + G+ T
Sbjct: 582 LSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQAT 633
Score = 56.2 bits (134), Expect = 9e-08
Identities = 84/369 (22%), Positives = 164/369 (44%), Gaps = 68/369 (18%)
Query: 148 EIKKFLAGCLKCSKE----EKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHT 203
EI+K L+ ++E E+ ++ + +A K L + K L+ + Q ++KLR E A
Sbjct: 459 EIEKAEQQILRATEEFKQLEEAIQLKKISEAGKDLLY--KQLSGRLQLVNKLRQE-ALDL 515
Query: 204 AALTNKHSQELTNEKEKALQAQV-------------QYQQQHEQQKKDLEILHQQNIHQL 250
K QE+ ++++ Q+ + Q +++ L+I+++Q QL
Sbjct: 516 ELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQQLDIMNKQ-YQQL 574
Query: 251 QNRLSELEAAN-------KDLTERKYKGDSTIRE-LKAKLSGVEEELQRTKQEVLSLRRE 302
++RL E+ + KDL E+ +G E LK L GV LQ + + +++ +
Sbjct: 575 ESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQ---EYLGTIKGQ 631
Query: 303 NSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKN 362
+ EC + L ++ +EQE +DQL + +A E
Sbjct: 632 ATQAQNECRKLRDEKETLLQRLTEVEQE---RDQLEIVAMDA---------------ENM 673
Query: 363 QVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKL 422
+ +L +LE+ ++ E + N +++ QGDL +L+ + + + L E+ EK+
Sbjct: 674 RKELAELESALQ----EQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKV 729
Query: 423 ----QKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKEL 478
Q EQ LQ E+ K ++ L+ + K + S++ + N +L L
Sbjct: 730 TRLTQLEQSALQ----------AELEKERQALKNALGKAQFSEEKEQENSELHAKLKHLQ 779
Query: 479 NENQLVRKQ 487
++N L+++Q
Sbjct: 780 DDNNLLKQQ 788
Score = 55.8 bits (133), Expect = 1e-07
Identities = 64/315 (20%), Positives = 135/315 (42%), Gaps = 39/315 (12%)
Query: 155 GCLKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQEL 214
G L C+ E +L++ +L+ + L KK+E W + + K +EL
Sbjct: 1309 GVLHCNVPEH----HNLENEVSRLEDIMQHLKSKKRE-----ERWMRASKRQSEKEMEEL 1359
Query: 215 TN------EKEKALQAQVQYQQ---QHEQQKKDL----------EILHQQNIHQLQNRLS 255
+ +++K+L+ +V+ Q QQ+KD E+ ++++ ++ +
Sbjct: 1360 HHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHEDIVD 1419
Query: 256 ELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEK 315
E+E K L +R+ S +RE L+ E EL TK++ + + + + E
Sbjct: 1420 EIECIEKTLLKRR----SELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTES 1475
Query: 316 HVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKS 375
+L+ + + DQ + + +++ K+ EE ++ + ++ +
Sbjct: 1476 DAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQC 1535
Query: 376 LSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQS 435
LS + K E ++KLQ D++ + ++L E E LQ ++ EL+ +
Sbjct: 1536 LSKKKEKLTEELQKLQKDIE-------MAERNEDHHLQVLKESEVLLQAKRAELEKLKSQ 1588
Query: 436 LRIKEQEVCKLQEQL 450
+ ++QE+ L QL
Sbjct: 1589 VTSQQQEMAVLDRQL 1603
Score = 55.1 bits (131), Expect = 2e-07
Identities = 58/253 (22%), Positives = 105/253 (41%), Gaps = 25/253 (9%)
Query: 234 QQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTK 293
Q +K++E LH NI L LE ++L K ++ K + G E L
Sbjct: 1351 QSEKEMEELHH-NIDDLLQEKKSLECEVEELHRTVQKR----QQQKDFIDGNVESLMTEL 1405
Query: 294 QEVLSLRRENSTLD-VECHEK-----EKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDT 347
+ SL+ +D +EC EK + + +A E E+ + E F
Sbjct: 1406 EIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTD 1465
Query: 348 IQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTV 407
+ + E + E+ LE + + L+KA++ ++ LQ D K L
Sbjct: 1466 AKRSLLQTESDAEE-------LERRAQETAVNLVKADQQLRSLQADAKDL-------EQH 1511
Query: 408 TIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNN 467
I+QE++L E + + + + Q + + +E+ KLQ+ +E + + Q+LK +
Sbjct: 1512 KIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKES 1571
Query: 468 EKLITWLNKELNE 480
E L+ EL +
Sbjct: 1572 EVLLQAKRAELEK 1584
Score = 53.9 bits (128), Expect = 5e-07
Identities = 94/375 (25%), Positives = 168/375 (44%), Gaps = 62/375 (16%)
Query: 158 KCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQ----ELDKLRNEWASHTAALTNKHSQE 213
K +EE L + + A K DF + L++KK+ EL KL+ + A H +
Sbjct: 1512 KIKQEEILKEINKIV-AAKDSDF--QCLSKKKEKLTEELQKLQKD--IEMAERNEDHHLQ 1566
Query: 214 LTNEKEKALQAQ----VQYQQQHEQQKKDLEILHQQ------NIHQLQNRLSELEAANKD 263
+ E E LQA+ + + Q Q++++ +L +Q +H LQ + + +A D
Sbjct: 1567 VLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKA---D 1623
Query: 264 LTERKYKGDST-------IRELKAKLSGVEEELQRTKQEV-LSLRRENSTLDVECHEKEK 315
L E G++ IRE+K+ L EEL K E+ + + + L + E EK
Sbjct: 1624 LQEALRLGETEVTEKCNHIREVKSLL----EELSFQKGELNVQISERKTQLTLIKQEIEK 1679
Query: 316 HVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEAT--- 372
LQ VL Q K K +L K D +Q + L+ ++ ++ +LE T
Sbjct: 1680 EEENLQV---VLRQMSKHKTEL----KNILDMLQLENHELQGLKLQHDQRVSELEKTQVA 1732
Query: 373 IKSLSAELLKANEIIKKLQGDL---KTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKEL 429
+ EL +I ++ +G++ K L+ + K + + + L E L KE+++L
Sbjct: 1733 VLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDL 1792
Query: 430 QD--------VGQSLRI--KEQEVCKLQ----EQLEATVKKLEESKQLLKNNEKLITWLN 475
Q+ + Q+ R+ +E K++ E+LE V+KL++ L N +KL +
Sbjct: 1793 QEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQL-NRDKLSLHND 1851
Query: 476 KELNENQLVRKQDVL 490
+ QL K++ +
Sbjct: 1852 ISAMQQQLQEKREAV 1866
Score = 47.8 bits (112), Expect = 3e-05
Identities = 97/439 (22%), Positives = 174/439 (39%), Gaps = 123/439 (28%)
Query: 159 CSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASH-----TAALTNKHSQ- 212
C KEE+ Q L +++ + L +++ +L+ E S T+ +T K Q
Sbjct: 1918 CQKEEETK-QQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQH 1976
Query: 213 ----ELTNEKEK---------ALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSEL-- 257
ELT++K K A + +V+ Q+ E+ + LE Q QL R +L
Sbjct: 1977 QLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVE 2036
Query: 258 ----------EA----------ANKDLTERKYKGDSTIRELKAKL----SGVEEELQRTK 293
EA N+ LTERK K + + LK L S +E+ L K
Sbjct: 2037 KSGELLALQKEADSMRADFSLLRNQFLTERK-KAEKQVASLKEALKIQRSQLEKNLLEQK 2095
Query: 294 QEVLSLRRENSTLDV---ECHEKE----KHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFD 346
QE +++E +T+++ + HE+ K +NQ+Q + L++++ ++ L R E D
Sbjct: 2096 QENSCIQKEMATIELVAQDNHERARRLMKELNQMQYEYTELKKQMANQKDLERRQMEISD 2155
Query: 347 TIQEQK----------------------VVLEENGEKNQVQLGKLEATIKSLSAELLKAN 384
++ K LE E+N+ G+LE+
Sbjct: 2156 AMRTLKSEVKDEIRTSLKNLNQFLPELPADLEAILERNENLEGELES------------- 2202
Query: 385 EIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAE--KEEKLQKEQKELQDVGQSLRIKEQE 442
L+ +L M + + + Q ++ E + E L+++ + +D R+K Q
Sbjct: 2203 -----LKENLPFTMNEGPFEEKLNFSQVHIMDEHWRGEALREKLRHRED-----RLKAQL 2252
Query: 443 VCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQDVLGPSTTPPAHSSS 502
+ +Q E +K +++ L + L R+ D LG T S
Sbjct: 2253 RHCMSKQAEVLIKGKRQTEGTL----------------HSLRRQVDALGELVT------S 2290
Query: 503 NTIRSGISPNLNVVDGRLT 521
+ S SP+L+ ++ LT
Sbjct: 2291 TSADSASSPSLSQLESSLT 2309
Score = 46.6 bits (109), Expect = 7e-05
Identities = 79/349 (22%), Positives = 136/349 (38%), Gaps = 66/349 (18%)
Query: 153 LAGCLKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQ 212
L L+ E SL Q+ D + L + E ++L+ E T LT
Sbjct: 680 LESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTR-LTQLEQS 738
Query: 213 ELTNEKEKALQA------QVQYQQQHEQQKKDLEI----------LHQQNIHQLQNRLS- 255
L E EK QA + Q+ ++ EQ+ +L L +Q + QN L+
Sbjct: 739 ALQAELEKERQALKNALGKAQFSEEKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNH 798
Query: 256 --------ELEAANKDLTERKYK---GDSTIRELKAKLSGVEEELQRTKQEVLSLRR-EN 303
E AA D RK K G+ I L +LQ+ E+L+ + E
Sbjct: 799 VVDGLVRPEEVAARVDELRRKLKLGTGEMNIHSPSDVLGKSLADLQKQFSEILARSKWER 858
Query: 304 STLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQ 363
V + ++ + Q K+A ++E + + L + FD Q + + + E +
Sbjct: 859 DEAQVRERKLQEEMALQQEKLATGQEEFRQACERALEARMNFDKRQHEARIQQMENEIHY 918
Query: 364 VQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQ 423
+Q E LK+ E I+ L T Q + E++E++
Sbjct: 919 LQ-------------ENLKSMEEIQGL-----------------TDLQLQEADEEKERIL 948
Query: 424 KEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLIT 472
+ +EL+ + K+ E K QEQ+ K+L++ K+ + ++KL T
Sbjct: 949 AQLRELE------KKKKLEDAKSQEQVFGLDKELKKLKKAVATSDKLAT 991
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 83.6 bits (205), Expect = 5e-16
Identities = 65/286 (22%), Positives = 148/286 (51%), Gaps = 28/286 (9%)
Query: 207 TNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTE 266
+++H + L E L+AQVQ + QK +L Q ++ Q+ + +LE +DL
Sbjct: 102 SHQHQEALRRE----LEAQVQTIRILTCQKTEL----QMALYYSQHAVKQLEGEARDLIS 153
Query: 267 RKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAV 326
R + EL+ LS V + ++ + + L +E L +E + +L+ K A
Sbjct: 154 RLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 213
Query: 327 LEQEIK----DKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLK 382
L+++++ +K ++ L KE ++ K++L + ++ Q + L ++S+SA
Sbjct: 214 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ--QQLQAEADHLGKELQSVSA---- 267
Query: 383 ANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQE 442
KLQ ++ + +L N + QQE+ + +EEK+Q+ ++++Q+ + +R +E++
Sbjct: 268 ------KLQAQVE----ENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEK 317
Query: 443 VCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQD 488
+ + +E + +K+ ++++ E+ I L ++++E + +R+Q+
Sbjct: 318 MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQE 363
Score = 76.3 bits (186), Expect = 9e-14
Identities = 68/347 (19%), Positives = 175/347 (50%), Gaps = 20/347 (5%)
Query: 157 LKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKK--QELDKLRNEWASHTAALTNK-HSQE 213
L+ + EK + ++ + ++L+ + L +++ E D L E S +A L + E
Sbjct: 218 LQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENE 277
Query: 214 LTN-----EKEKALQAQVQYQQQHEQQKKDLEILHQQN--IHQLQNRLSELEAANKDLTE 266
L N ++EK + + + Q++ E+ ++ E + +Q + + + + E E + E
Sbjct: 278 LWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE 337
Query: 267 RKYKGDSTIRELKAKLSGVE----EELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQT 322
++ + IREL+ K+ E +E +R ++E + + + + + +E+ + + +
Sbjct: 338 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 397
Query: 323 KVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLK 382
K+ E+ ++++++ + +E +E+ EE + + ++ + E I+ ++ +
Sbjct: 398 KIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 457
Query: 383 ANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQE 442
E++++ + + GK+ + +QE+ + +EEK+++++K++++ Q +I+EQE
Sbjct: 458 QEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIRE--QEEKIREQE 515
Query: 443 VCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQDV 489
+QEQ E K E+ +++ + EK+ K + + +R+Q+V
Sbjct: 516 E-MMQEQEE---KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEV 558
Score = 75.9 bits (185), Expect = 1e-13
Identities = 52/262 (19%), Positives = 140/262 (53%), Gaps = 22/262 (8%)
Query: 209 KHSQELTNEKEKALQAQVQYQQQHEQQKKDLE--------ILHQQNIHQLQNRLSELEAA 260
+ +E+ EKE+ ++ Q + + E++ ++LE I Q+ Q + ++ E E
Sbjct: 319 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK- 377
Query: 261 NKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQL 320
++ + ++ + IRE + K+ EE +Q ++++ + + E E+E+ + +
Sbjct: 378 RQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQ 437
Query: 321 QTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKL---EATIKSLS 377
+ K+ E++I+++++ I+EQ+ +++E EK Q GK+ EA ++
Sbjct: 438 EEKIREQEKKIREQEE----------KIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQE 487
Query: 378 AELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLR 437
++ + E I++ + ++ K++ + + +QE+ + E+EEK+ ++++++Q+ + +R
Sbjct: 488 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 547
Query: 438 IKEQEVCKLQEQLEATVKKLEE 459
+E+++ + + +L +K++E
Sbjct: 548 RQEEKMREQEVRLRQQEEKMQE 569
Score = 57.8 bits (138), Expect = 3e-08
Identities = 52/290 (17%), Positives = 138/290 (47%), Gaps = 50/290 (17%)
Query: 161 KEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEK 220
KEEK M+ ++ + + + L EK E +K+R + + ++ ++ K
Sbjct: 328 KEEK---MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 384
Query: 221 ALQAQVQYQQQHEQQKKDLEILHQQN--IHQLQNRLSELEAANKDLTERKYKGDSTIREL 278
+ + + ++Q E+ ++ E++ +Q + + + ++ E E ++ E+ + + IRE
Sbjct: 385 MWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQ 444
Query: 279 KAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLV 338
+ K+ EE+++ ++ + + + + E+E + + + K+ E++I+++++
Sbjct: 445 EKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEK-- 502
Query: 339 LRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLM 398
+ +E + I+EQ+ +++E EK Q K+
Sbjct: 503 -KIREQEEKIREQEEMMQEQEEKMWEQEEKM----------------------------- 532
Query: 399 GKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQE 448
+QE+ + E+EEK++++++++++ Q +R+++QE K+QE
Sbjct: 533 ----------CEQEEKMQEQEEKMRRQEEKMRE--QEVRLRQQEE-KMQE 569
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 82.8 bits (203), Expect = 9e-16
Identities = 90/345 (26%), Positives = 160/345 (46%), Gaps = 26/345 (7%)
Query: 161 KEEKLSLMQSLDDATKQLDFTRKT---LAEKKQELDKLRNEWASHTAALTNKHSQELTNE 217
++ K L Q LDD LD R++ L +K+++ D+L E + +A + +
Sbjct: 1412 EKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEA 1471
Query: 218 KEKALQAQVQYQQQHE--QQKKDLEILHQQNIHQLQNRLSELEAANK---DLTERKYKGD 272
+EK +A + E +QK +LE L++Q ++++ +S + K +L + K +
Sbjct: 1472 REKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALE 1531
Query: 273 STIRELKAKLSGVEEELQRTKQEVLSLR-----------RENSTLDVECHEKEKH-VNQL 320
+ E+K +L +E+ELQ T+ L L R+ D + EK+K V Q+
Sbjct: 1532 QQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQV 1591
Query: 321 QTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLE---ENGEKNQVQLGKLEATIKSLS 377
+ A LE E K + V K+ +++ + ++ +N ++ QL KL+A +K
Sbjct: 1592 REMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCM 1651
Query: 378 AELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQ-QEKLLAEKEEK--LQKEQKELQDVGQ 434
EL +++ K KLK IQ QE+L A + K Q+E+ EL D
Sbjct: 1652 RELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIA 1711
Query: 435 SLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELN 479
+ K + + +LEA + +LEE + + N +LI K+ N
Sbjct: 1712 NSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKAN 1756
Score = 74.3 bits (181), Expect = 3e-13
Identities = 80/352 (22%), Positives = 165/352 (46%), Gaps = 38/352 (10%)
Query: 163 EKLSLMQSLDDATK---QLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKE 219
EKL L + L T+ + + R L KKQEL+++ ++ + + Q L EK+
Sbjct: 881 EKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEE-EEERCQHLQAEKK 939
Query: 220 KALQAQVQYQQQHEQ-----QKKDLE----------------ILHQQNIHQ------LQN 252
K Q + ++Q E+ QK LE IL QN L++
Sbjct: 940 KMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLED 999
Query: 253 RLSELEAANKDLTERKYKGDSTIR---ELKAKLSGVEEELQRTKQEVLSLRRENSTLDVE 309
R++E +LTE + K S + + +A ++ +EE L+R +++ L + L+ +
Sbjct: 1000 RIAEFTT---NLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGD 1056
Query: 310 CHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKL 369
+ + +LQ ++A L+ ++ K++ + + QK + + + + Q+ +L
Sbjct: 1057 STDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISEL 1116
Query: 370 EATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKEL 429
+ ++S A KA + + L +L+ L +L+ T Q++L +++E+++ +K L
Sbjct: 1117 QEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTL 1176
Query: 430 QDVGQSLRIKEQEVCKLQEQ-LEATVKKLEESKQLLKNNEKLITWLNKELNE 480
++ ++ + QE+ + Q +E ++LE++K++ N EK L E E
Sbjct: 1177 EEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGE 1228
Score = 67.8 bits (164), Expect = 3e-11
Identities = 69/309 (22%), Positives = 146/309 (47%), Gaps = 39/309 (12%)
Query: 182 RKTLAEKKQELDKLRNEWASHTAALTNKHSQ--ELTNEKEKALQAQVQYQQQHEQQKKDL 239
RK A+++Q+L ++ + A L ++ Q L + + LQ Q ++ ++++ +
Sbjct: 796 RKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELV 855
Query: 240 EILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIR----------ELKAKLSGVEEEL 289
++ +Q +NRL+E+E L K + ++ EL+A+L+ ++EL
Sbjct: 856 KVREKQLA--AENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQEL 913
Query: 290 QRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKD------QLVLRTKE 343
+ ++ + E + C + ++Q + LE+++++++ QL T E
Sbjct: 914 EEICHDLEARVEEE---EERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTE 970
Query: 344 A-FDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLK 402
A ++E++++LE+ K + LE I + L + E K L K
Sbjct: 971 AKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLA----------K 1020
Query: 403 LKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESK- 461
LKN + E ++ + EE+L++E+K+ Q++ ++ R E + L +Q+ ++ E K
Sbjct: 1021 LKN----KHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKM 1076
Query: 462 QLLKNNEKL 470
QL K E+L
Sbjct: 1077 QLAKKEEEL 1085
Score = 66.2 bits (160), Expect = 9e-11
Identities = 62/321 (19%), Positives = 142/321 (44%), Gaps = 10/321 (3%)
Query: 161 KEEKL-SLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELT-NEK 218
KEE+L + + +++ Q + K + E + ++ +L+ + S A+ Q+ E+
Sbjct: 1081 KEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEE 1140
Query: 219 EKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANK-DLTERKYKGDSTIRE 277
+AL+ +++ +++L +Q ++ L+ L E ++ + E + K + E
Sbjct: 1141 LEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEE 1200
Query: 278 LKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQL 337
L E+L++TK+ +L + TL+ E E V L E + K +
Sbjct: 1201 LA-------EQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQ 1253
Query: 338 VLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTL 397
+ + F+ + + L + K QV+L + + ++ K + L+ L+
Sbjct: 1254 LQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDT 1313
Query: 398 MGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKL 457
L+ +N + L + E++ +++L++ ++ E+++ L Q+ KK+
Sbjct: 1314 QELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKM 1373
Query: 458 EESKQLLKNNEKLITWLNKEL 478
E+S L+ E++ L K+L
Sbjct: 1374 EDSVGCLETAEEVKRKLQKDL 1394
Score = 62.0 bits (149), Expect = 2e-09
Identities = 78/320 (24%), Positives = 141/320 (44%), Gaps = 46/320 (14%)
Query: 162 EEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQ--ELTNEKE 219
E +L+ M++L QL + L E+ Q +L E A LT K + E+ ++ E
Sbjct: 865 ENRLTEMETLQS---QLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLE 921
Query: 220 KALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELK 279
++ + + Q + +KK + QQNI +L+ +L E E+A + L K
Sbjct: 922 ARVEEEEERCQHLQAEKKKM----QQNIQELEEQLEEEESARQKLQLEKVT--------- 968
Query: 280 AKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVL 339
E +L++ ++E + L +N L E E + + T + E+E K K L
Sbjct: 969 -----TEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLT--EEEEKSKSLAKL 1021
Query: 340 RTK-EAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLM 398
+ K EA T E+++ EE Q +LE T + L + ++ I +LQ +
Sbjct: 1022 KNKHEAMITDLEERLRREEK------QRQELEKTRRKLEGDSTDLSDQIAELQAQI---- 1071
Query: 399 GKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLE 458
+LK++ LA+KEE+LQ +++ + +++ +L+ Q+ + LE
Sbjct: 1072 AELKMQ----------LAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLE 1121
Query: 459 ESKQLLKNNEKLITWLNKEL 478
+ EK L +EL
Sbjct: 1122 SERASRNKAEKQKRDLGEEL 1141
Score = 59.3 bits (142), Expect = 1e-08
Identities = 80/372 (21%), Positives = 161/372 (43%), Gaps = 37/372 (9%)
Query: 132 KHLTHLSLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFTRKT------- 184
K LSL +E K L K + E LM S DD K + K+
Sbjct: 1474 KETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQ 1533
Query: 185 LAEKKQELDKLRNEWAS----------HTAALTNKHSQELTNEKEKALQAQVQYQQQHEQ 234
+ E K +L++L +E + + A+ + ++L E++ + + Q +Q +
Sbjct: 1534 VEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVRE 1593
Query: 235 QKKDLEILHQQNI------HQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEE 288
+ +LE +Q +L+ L +LEA + + + +R+L+A++ E
Sbjct: 1594 MEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRE 1653
Query: 289 LQRT---KQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLE----QEIKDKDQL---V 338
L T ++E+L+ +EN + + E + QLQ ++A E Q +++D+L +
Sbjct: 1654 LDDTRASREEILAQAKEN---EKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEI 1710
Query: 339 LRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLM 398
+ E+K LE + + +L + + + ++ L KAN I ++ DL
Sbjct: 1711 ANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLER 1770
Query: 399 GKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQD-VGQSLRIKEQEVCKLQEQLEATVKKL 457
+ Q E+ E + KLQ+ + ++ S+ E ++ +L+EQL+ K+
Sbjct: 1771 SHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKER 1830
Query: 458 EESKQLLKNNEK 469
+ + + ++ EK
Sbjct: 1831 QAACKQVRRTEK 1842
Score = 58.2 bits (139), Expect = 2e-08
Identities = 73/326 (22%), Positives = 137/326 (42%), Gaps = 40/326 (12%)
Query: 164 KLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQ 223
K L +LD Q + K E L E +H A + QE+ + +A++
Sbjct: 1145 KTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQI-----QEMRQKHSQAVE 1199
Query: 224 AQVQYQQQHEQQKKDLEILHQ---QNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKA 280
+ +Q ++ K +LE Q +L N + L D ++ K ++ ++EL+
Sbjct: 1200 ELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQV 1259
Query: 281 KLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVL- 339
K + E +V L+ E + + + ++L + LE +++D +L+
Sbjct: 1260 KFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQE 1319
Query: 340 --RTKEAFDT----IQEQKVVLEENGEKNQVQLGKLEATIKSLSAE-------------- 379
R K + T ++++K E E+ + LE I +L A+
Sbjct: 1320 ENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGC 1379
Query: 380 LLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLA-EKEEKLQ-KEQKELQDVGQSLR 437
L A E+ +KLQ DL+ L + +EK+ A +K EK + + Q+EL D+ L
Sbjct: 1380 LETAEEVKRKLQKDLEGLSQR---------HEEKVAAYDKLEKTKTRLQQELDDLLVDLD 1430
Query: 438 IKEQEVCKLQEQLEATVKKLEESKQL 463
+ Q C L+++ + + L E K +
Sbjct: 1431 HQRQSACNLEKKQKKFDQLLAEEKTI 1456
Score = 56.2 bits (134), Expect = 9e-08
Identities = 77/382 (20%), Positives = 155/382 (40%), Gaps = 61/382 (15%)
Query: 169 QSLDDATKQLDFTRKT---LAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQ 225
Q++++ +QL+ T++ L + KQ L+ R E A+ L + K K ++AQ
Sbjct: 1196 QAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGD--SEHKRKKVEAQ 1253
Query: 226 VQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGV 285
+Q Q + + + + +LQ L + + K L+++L
Sbjct: 1254 LQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDT 1313
Query: 286 EEELQRTKQEVLSLRR-------ENSTLDVECHEKEKHVNQLQTKVAVLEQEI------- 331
+E LQ ++ LSL E ++ + E+E+ + L+ ++A L ++
Sbjct: 1314 QELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKM 1373
Query: 332 ------------------KDKDQLVLRTKE---AFDTIQEQKVVLEE------------- 357
KD + L R +E A+D +++ K L++
Sbjct: 1374 EDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQR 1433
Query: 358 ----NGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEK 413
N EK Q + +L A K++SA+ + + + + +T L ++Q+
Sbjct: 1434 QSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKA 1493
Query: 414 LLAEKEEKLQKEQKELQ----DVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEK 469
L ++ + E ++L DVG+S+ E+ L++Q+E +LEE + L+ E
Sbjct: 1494 ELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATED 1553
Query: 470 LITWLNKELNENQLVRKQDVLG 491
L L + ++D+ G
Sbjct: 1554 AKLRLEVNLQAMKAQFERDLQG 1575
Score = 50.8 bits (120), Expect = 4e-06
Identities = 70/313 (22%), Positives = 135/313 (43%), Gaps = 47/313 (15%)
Query: 166 SLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQ 225
S ++ D+A KQL RK A+ K + +L + AS L E +K K+++A+
Sbjct: 1628 SANKNRDEAIKQL---RKLQAQMKDCMRELDDTRASREEILAQAKENE---KKLKSMEAE 1681
Query: 226 VQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGV 285
+ Q+ + + QQ +L + ++ E K R L+A+++ +
Sbjct: 1682 MIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEK-------RRLEARIAQL 1734
Query: 286 EEELQ-----------RTKQEVLSLRRENSTLDVECHEKEKHVN----------QLQTKV 324
EEEL+ R K+ L + + N+ L++E +K+ N +L+ K+
Sbjct: 1735 EEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKL 1794
Query: 325 AVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKAN 384
+E +K K + + EA I + + L+ ++ Q ++ T K L LL+ +
Sbjct: 1795 QEMEGTVKSKYKASITALEA--KIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVD 1852
Query: 385 EIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQ-------KEQKELQDVGQSLR 437
+ + + + +T Q ++ L E EE+ Q K Q+EL+D ++
Sbjct: 1853 DERRNAE----QYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETAD 1908
Query: 438 IKEQEVCKLQEQL 450
+EV L+ +L
Sbjct: 1909 AMNREVSSLKNKL 1921
Score = 49.7 bits (117), Expect = 9e-06
Identities = 62/294 (21%), Positives = 118/294 (40%), Gaps = 49/294 (16%)
Query: 167 LMQSLDDATKQLDFTRKT----LAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKAL 222
L + D ++LD TR + LA+ K+ KL++ A +L E A
Sbjct: 1643 LQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMI---------QLQEELAAAE 1693
Query: 223 QAQVQYQQQHEQ-----------------QKKDLEILHQQNIHQLQNRLSELEAANKDLT 265
+A+ Q QQ+ ++ +K+ LE I QL+ L E + + +
Sbjct: 1694 RAKRQAQQERDELADEIANSSGKGALALEEKRRLEA----RIAQLEEELEEEQGNTELIN 1749
Query: 266 ERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQ------ 319
+R K + I ++ L+ Q+ + L R+N L V+ E E V
Sbjct: 1750 DRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASI 1809
Query: 320 --LQTKVAVLEQEIKDKDQ-------LVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLE 370
L+ K+A LE+++ ++ + V RT++ + Q N E+ + Q K
Sbjct: 1810 TALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKAS 1869
Query: 371 ATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQK 424
+K L +L +A E ++ + L +L+ + ++ + KL++
Sbjct: 1870 TRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRR 1923
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 82.8 bits (203), Expect = 9e-16
Identities = 121/498 (24%), Positives = 216/498 (43%), Gaps = 57/498 (11%)
Query: 12 LQVKCKDCEERRVSIRMSIELQSVSNPVHRKDLVIRLTDDTDPFFLYNLVISEEDFQSLK 71
L+V+ ++ E R ++ I ++ + ++DL + V E + QSL
Sbjct: 486 LKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKF------------VAKENEVQSLH 533
Query: 72 FQQGLLVDFLAFPQKFIDLLQQCTQEHAKEIPRFLLQLVSPAAILDNSPAFLNVVETNPF 131
+ L D L Q+ L Q + K + + + IL+ + A ++
Sbjct: 534 SK---LTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHS 590
Query: 132 KHLTHLSLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDAT------KQLDFTRKTL 185
+ S +L E+ K +A K K+ + SL D T K + L
Sbjct: 591 QIAAQTSASVLAE---ELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLL 647
Query: 186 AEKKQELDKLRNEWASHTAALTN-KHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQ 244
+ Q+L L NE A+ L + S + ++K + L+ Q+Q++ ++ + + +IL+
Sbjct: 648 KAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKME--EFKILND 705
Query: 245 QN------IHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQR------T 292
QN + +LQ +SE NKD+ E+ K I+E KL VEE L+ T
Sbjct: 706 QNKALKSEVQKLQTLVSE--QPNKDVVEQMEK---CIQEKDEKLKTVEELLETGLIQVAT 760
Query: 293 KQEVLS-LRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIK----DKDQLVLRTKEAFDT 347
K+E L+ +R ENS+L E + + N Q A L +E+K +KD + +E +
Sbjct: 761 KEEELNAIRTENSSLTKEVQDLKAKQND-QVSFASLVEELKKVIHEKDGKIKSVEELLEA 819
Query: 348 IQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTV 407
+ E+ + + ++ L+ I ++ E + I K+Q L GK + NT+
Sbjct: 820 ELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTM 879
Query: 408 TIQQEKLLAEKEEKLQKEQKELQDV---GQSLRIKEQEVCKLQEQLEATVKKLEESKQLL 464
+ +L EKE+ L K LQD+ +SL+ QEV + + ++ + EE + +L
Sbjct: 880 ----KAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVL 935
Query: 465 KNNEKLITWLNKELNENQ 482
K E + L L E +
Sbjct: 936 KEKENELKRLEAMLKERE 953
Score = 63.5 bits (153), Expect = 6e-10
Identities = 86/376 (22%), Positives = 163/376 (43%), Gaps = 51/376 (13%)
Query: 146 DVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAA 205
+++ K G ++ K ++LS+ + + L + + K L++ + A+
Sbjct: 837 EIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLAN---- 892
Query: 206 LTNKHSQELTNEKEKALQAQVQYQQQHE-------QQKKDLEILHQQNIHQLQNRLSELE 258
T K Q+L E E +L+A VQ QH Q ++LEI+ ++ ++L+ + L+
Sbjct: 893 -TGKWLQDLQEENE-SLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLK 950
Query: 259 AANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHV- 317
DL+ + E K S +E+ Q+ Q+ S L V E+EK +
Sbjct: 951 ERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKV-ISEREKEIS 1009
Query: 318 ---NQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKN------QVQLGK 368
N+L + +E + K + L + EA + + + +L++ K QV+ +
Sbjct: 1010 GLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVE 1069
Query: 369 LEA--TIKSLSAELL----------------KANEIIKKLQG--DLKTLMGKLK----LK 404
LEA +K L ++ KA E + G ++K L KLK +
Sbjct: 1070 LEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMH 1129
Query: 405 NTVTIQQEK---LLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESK 461
+ ++ EK +LAE E LQK Q+ ++ ++K E K +Q++++ E+
Sbjct: 1130 TLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQEL 1189
Query: 462 QLLKNNEKLITWLNKE 477
+ L++ K I L +E
Sbjct: 1190 ERLRSENKDIENLRRE 1205
Score = 62.8 bits (151), Expect = 1e-09
Identities = 89/436 (20%), Positives = 187/436 (42%), Gaps = 98/436 (22%)
Query: 127 ETNPFKHLTHLSLKLLPGNDV---EIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFTRK 183
E N F++ H+S + + ++++ + + K+E L ++ + T QL+
Sbjct: 386 EHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLE---- 441
Query: 184 TLAEKKQELDKLRNEWASHTAALTNKHSQ------ELTNEKEKALQAQVQYQQ------- 230
+++ EL+KLR ++A LT K + + N ++ A Q +VQ Q+
Sbjct: 442 --SKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEE 499
Query: 231 ----------QHEQQKKDLE---ILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRE 277
+HE ++DL+ + + + L ++L++ + + L +R + + E
Sbjct: 500 VQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQ----LME 555
Query: 278 LKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQE----IKD 333
+ K EE LQ Q++L +N L + + + QT +VL +E I +
Sbjct: 556 SEQKRVNKEESLQMQVQDILE---QNEALKAQIQQFHSQI-AAQTSASVLAEELHKVIAE 611
Query: 334 KDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSA----------ELLKA 383
KD+ + +T+++ + +++ EE + Q L+A ++ L A EL K
Sbjct: 612 KDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKM 671
Query: 384 NEII-----------KKLQGDLKTLMGKLKLKNT-----------------------VTI 409
+ + ++LQ ++ M + K+ N V
Sbjct: 672 QQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVE 731
Query: 410 QQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEK 469
Q EK + EK+EKL+ ++ L+ + KE+E+ ++ + + K++++ K K N++
Sbjct: 732 QMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLK--AKQNDQ 789
Query: 470 -----LITWLNKELNE 480
L+ L K ++E
Sbjct: 790 VSFASLVEELKKVIHE 805
Score = 47.0 bits (110), Expect = 6e-05
Identities = 47/239 (19%), Positives = 97/239 (40%), Gaps = 17/239 (7%)
Query: 247 IHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTL 306
IHQLQ + L A +D K + +E+ + + R K + +L +E++
Sbjct: 331 IHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVF 390
Query: 307 DVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQL 366
+ H + Q+Q K + ++++ E + +ENG
Sbjct: 391 QNKIHVSYQETQQMQMKFQQVREQME----------------AEIAHLKQENGILRDAVS 434
Query: 367 GKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQ 426
SAEL K + +L +L GKL+ + E+ + + +LQ+ +
Sbjct: 435 NTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAE 494
Query: 427 KELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVR 485
+ ++V +R + E Q+ L++ E Q L +++ T ++K+ E +L++
Sbjct: 495 RRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSL-HSKLTDTLVSKQQLEQRLMQ 552
Score = 37.4 bits (85), Expect = 0.044
Identities = 38/209 (18%), Positives = 91/209 (43%), Gaps = 29/209 (13%)
Query: 161 KEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEK 220
++E+ +D++ K + + + +QEL++LR+E NK + L E+E
Sbjct: 1158 EQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSE---------NKDIENLRREREH 1208
Query: 221 A---LQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRE 277
L+ + + + ++L+ L + +L + SE N++L K + + T+ +
Sbjct: 1209 LEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTK 1268
Query: 278 LKAK----------LSGVEEELQRTKQEVLSLRRENSTLD-------VECHEKEKHVNQL 320
L+ + L ++ L+ + +++ + + ++ E EKE L
Sbjct: 1269 LRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSL 1328
Query: 321 QTKVAVLEQEIKDKDQLVLRTKEAFDTIQ 349
V L+Q ++ +Q + + KE + ++
Sbjct: 1329 NQTVTQLQQLLQAVNQQLTKEKEHYQVLE 1357
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 82.8 bits (203), Expect = 9e-16
Identities = 121/498 (24%), Positives = 216/498 (43%), Gaps = 57/498 (11%)
Query: 12 LQVKCKDCEERRVSIRMSIELQSVSNPVHRKDLVIRLTDDTDPFFLYNLVISEEDFQSLK 71
L+V+ ++ E R ++ I ++ + ++DL + V E + QSL
Sbjct: 486 LKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKF------------VAKENEVQSLH 533
Query: 72 FQQGLLVDFLAFPQKFIDLLQQCTQEHAKEIPRFLLQLVSPAAILDNSPAFLNVVETNPF 131
+ L D L Q+ L Q + K + + + IL+ + A ++
Sbjct: 534 SK---LTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHS 590
Query: 132 KHLTHLSLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDAT------KQLDFTRKTL 185
+ S +L E+ K +A K K+ + SL D T K + L
Sbjct: 591 QIAAQTSASVLAE---ELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLL 647
Query: 186 AEKKQELDKLRNEWASHTAALTN-KHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQ 244
+ Q+L L NE A+ L + S + ++K + L+ Q+Q++ ++ + + +IL+
Sbjct: 648 KAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKME--EFKILND 705
Query: 245 QN------IHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQR------T 292
QN + +LQ +SE NKD+ E+ K I+E KL VEE L+ T
Sbjct: 706 QNKALKSEVQKLQTLVSE--QPNKDVVEQMEK---CIQEKDEKLKTVEELLETGLIQVAT 760
Query: 293 KQEVLS-LRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIK----DKDQLVLRTKEAFDT 347
K+E L+ +R ENS+L E + + N Q A L +E+K +KD + +E +
Sbjct: 761 KEEELNAIRTENSSLTKEVQDLKAKQND-QVSFASLVEELKKVIHEKDGKIKSVEELLEA 819
Query: 348 IQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTV 407
+ E+ + + ++ L+ I ++ E + I K+Q L GK + NT+
Sbjct: 820 ELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTM 879
Query: 408 TIQQEKLLAEKEEKLQKEQKELQDV---GQSLRIKEQEVCKLQEQLEATVKKLEESKQLL 464
+ +L EKE+ L K LQD+ +SL+ QEV + + ++ + EE + +L
Sbjct: 880 ----KAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVL 935
Query: 465 KNNEKLITWLNKELNENQ 482
K E + L L E +
Sbjct: 936 KEKENELKRLEAMLKERE 953
Score = 62.8 bits (151), Expect = 1e-09
Identities = 89/436 (20%), Positives = 187/436 (42%), Gaps = 98/436 (22%)
Query: 127 ETNPFKHLTHLSLKLLPGNDV---EIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFTRK 183
E N F++ H+S + + ++++ + + K+E L ++ + T QL+
Sbjct: 386 EHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLE---- 441
Query: 184 TLAEKKQELDKLRNEWASHTAALTNKHSQ------ELTNEKEKALQAQVQYQQ------- 230
+++ EL+KLR ++A LT K + + N ++ A Q +VQ Q+
Sbjct: 442 --SKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEE 499
Query: 231 ----------QHEQQKKDLE---ILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRE 277
+HE ++DL+ + + + L ++L++ + + L +R + + E
Sbjct: 500 VQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQ----LME 555
Query: 278 LKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQE----IKD 333
+ K EE LQ Q++L +N L + + + QT +VL +E I +
Sbjct: 556 SEQKRVNKEESLQMQVQDILE---QNEALKAQIQQFHSQI-AAQTSASVLAEELHKVIAE 611
Query: 334 KDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSA----------ELLKA 383
KD+ + +T+++ + +++ EE + Q L+A ++ L A EL K
Sbjct: 612 KDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKM 671
Query: 384 NEII-----------KKLQGDLKTLMGKLKLKNT-----------------------VTI 409
+ + ++LQ ++ M + K+ N V
Sbjct: 672 QQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVE 731
Query: 410 QQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEK 469
Q EK + EK+EKL+ ++ L+ + KE+E+ ++ + + K++++ K K N++
Sbjct: 732 QMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLK--AKQNDQ 789
Query: 470 -----LITWLNKELNE 480
L+ L K ++E
Sbjct: 790 VSFASLVEELKKVIHE 805
Score = 59.3 bits (142), Expect = 1e-08
Identities = 77/348 (22%), Positives = 150/348 (43%), Gaps = 24/348 (6%)
Query: 146 DVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAA 205
+++ K G ++ K ++LS+ + + L + + K L++ + A+
Sbjct: 837 EIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLAN---- 892
Query: 206 LTNKHSQELTNEKEKALQAQVQYQQQHE-------QQKKDLEILHQQNIHQLQNRLSELE 258
T K Q+L E E +L+A VQ QH Q ++LEI+ ++ ++L+ + L+
Sbjct: 893 -TGKWLQDLQEENE-SLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLK 950
Query: 259 AANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVN 318
DL+ + E K S +E+ Q+ Q+ S L V E+EK ++
Sbjct: 951 ERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKV-ISEREKEIS 1009
Query: 319 QLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQ-EQKVVLEENGEKNQVQ--------LGKL 369
L ++ L+ ++ + + ++ + ++ E K VL++ K V L
Sbjct: 1010 GLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGF 1069
Query: 370 EATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKEL 429
E K A +E +K L+ LK L + + +LAE E LQK Q+ +
Sbjct: 1070 EKKAKECMAGT-SGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSV 1128
Query: 430 QDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKE 477
+ ++K E K +Q++++ E+ + L++ K I L +E
Sbjct: 1129 EQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRRE 1176
Score = 52.0 bits (123), Expect = 2e-06
Identities = 85/380 (22%), Positives = 165/380 (43%), Gaps = 64/380 (16%)
Query: 148 EIKKFLAGCLKCSKEEKLSLMQS-LDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAAL 206
E++ L G KEE+++ M++ L++ K L T K L + ++E + L+
Sbjct: 864 ELQNLLKG-----KEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLK---------- 908
Query: 207 TNKHSQELTNEKEKALQAQVQYQQ------QHEQQKKDLEILHQQNIHQLQNR---LSEL 257
H QE+ K + Q+++ + E + K LE + ++ L ++ L ++
Sbjct: 909 --AHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDV 966
Query: 258 EAANK-------DLTERKYKGDST----------IRELKAKLSGVEEELQRTKQEVLSLR 300
+ NK L ++ Y+ S+ I E + ++SG+ EL K V R
Sbjct: 967 QDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQR 1026
Query: 301 RENSTLDVECH----EKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTI-----QEQ 351
++N+ + E ++ + +L KV+V + + L K+A + + E+
Sbjct: 1027 KKNNERQQQVEAVELEAKEVLKKLFPKVSV-PSNLSYGEWLHGFEKKAKECMAGTSGSEE 1085
Query: 352 KVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLK-----NT 406
VLE ++ L+ + + L + I++KLQ ++ K K+K T
Sbjct: 1086 VKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKT 1145
Query: 407 VTIQQEKLLAEKE--EKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLL 464
+ Q + ++ E+L+ E K+++++ + E E+ K + + V ++ E K L
Sbjct: 1146 IKQMQSSFTSSEQELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKAQL 1205
Query: 465 KNNEKLITWLNKELNENQLV 484
NE L T L E NE Q V
Sbjct: 1206 --NETL-TKLRTEQNERQKV 1222
Score = 47.0 bits (110), Expect = 6e-05
Identities = 47/239 (19%), Positives = 97/239 (40%), Gaps = 17/239 (7%)
Query: 247 IHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTL 306
IHQLQ + L A +D K + +E+ + + R K + +L +E++
Sbjct: 331 IHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVF 390
Query: 307 DVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQL 366
+ H + Q+Q K + ++++ E + +ENG
Sbjct: 391 QNKIHVSYQETQQMQMKFQQVREQME----------------AEIAHLKQENGILRDAVS 434
Query: 367 GKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQ 426
SAEL K + +L +L GKL+ + E+ + + +LQ+ +
Sbjct: 435 NTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAE 494
Query: 427 KELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVR 485
+ ++V +R + E Q+ L++ E Q L +++ T ++K+ E +L++
Sbjct: 495 RRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSL-HSKLTDTLVSKQQLEQRLMQ 552
Score = 38.1 bits (87), Expect = 0.026
Identities = 33/190 (17%), Positives = 82/190 (43%), Gaps = 19/190 (10%)
Query: 161 KEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEK 220
++E+ +D++ K + + + +QEL++LR+E NK + L E+E
Sbjct: 1129 EQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSE---------NKDIENLRREREH 1179
Query: 221 ALQAQVQYQQQHEQQKKDLE-ILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELK 279
+ E +K ++E + + +L+ +L+E + + K + + +
Sbjct: 1180 L---------EMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQ 1230
Query: 280 AKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVL 339
L ++ ++ + + + + + + E EKE L V L+Q ++ +Q +
Sbjct: 1231 QSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAVNQQLT 1290
Query: 340 RTKEAFDTIQ 349
+ KE + ++
Sbjct: 1291 KEKEHYQVLE 1300
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 82.8 bits (203), Expect = 9e-16
Identities = 121/498 (24%), Positives = 216/498 (43%), Gaps = 57/498 (11%)
Query: 12 LQVKCKDCEERRVSIRMSIELQSVSNPVHRKDLVIRLTDDTDPFFLYNLVISEEDFQSLK 71
L+V+ ++ E R ++ I ++ + ++DL + V E + QSL
Sbjct: 486 LKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKF------------VAKENEVQSLH 533
Query: 72 FQQGLLVDFLAFPQKFIDLLQQCTQEHAKEIPRFLLQLVSPAAILDNSPAFLNVVETNPF 131
+ L D L Q+ L Q + K + + + IL+ + A ++
Sbjct: 534 SK---LTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHS 590
Query: 132 KHLTHLSLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDAT------KQLDFTRKTL 185
+ S +L E+ K +A K K+ + SL D T K + L
Sbjct: 591 QIAAQTSASVLAE---ELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLL 647
Query: 186 AEKKQELDKLRNEWASHTAALTN-KHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQ 244
+ Q+L L NE A+ L + S + ++K + L+ Q+Q++ ++ + + +IL+
Sbjct: 648 KAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKME--EFKILND 705
Query: 245 QN------IHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQR------T 292
QN + +LQ +SE NKD+ E+ K I+E KL VEE L+ T
Sbjct: 706 QNKALKSEVQKLQTLVSE--QPNKDVVEQMEK---CIQEKDEKLKTVEELLETGLIQVAT 760
Query: 293 KQEVLS-LRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIK----DKDQLVLRTKEAFDT 347
K+E L+ +R ENS+L E + + N Q A L +E+K +KD + +E +
Sbjct: 761 KEEELNAIRTENSSLTKEVQDLKAKQND-QVSFASLVEELKKVIHEKDGKIKSVEELLEA 819
Query: 348 IQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTV 407
+ E+ + + ++ L+ I ++ E + I K+Q L GK + NT+
Sbjct: 820 ELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTM 879
Query: 408 TIQQEKLLAEKEEKLQKEQKELQDV---GQSLRIKEQEVCKLQEQLEATVKKLEESKQLL 464
+ +L EKE+ L K LQD+ +SL+ QEV + + ++ + EE + +L
Sbjct: 880 ----KAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVL 935
Query: 465 KNNEKLITWLNKELNENQ 482
K E + L L E +
Sbjct: 936 KEKENELKRLEAMLKERE 953
Score = 63.5 bits (153), Expect = 6e-10
Identities = 86/376 (22%), Positives = 163/376 (43%), Gaps = 51/376 (13%)
Query: 146 DVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAA 205
+++ K G ++ K ++LS+ + + L + + K L++ + A+
Sbjct: 837 EIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLAN---- 892
Query: 206 LTNKHSQELTNEKEKALQAQVQYQQQHE-------QQKKDLEILHQQNIHQLQNRLSELE 258
T K Q+L E E +L+A VQ QH Q ++LEI+ ++ ++L+ + L+
Sbjct: 893 -TGKWLQDLQEENE-SLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLK 950
Query: 259 AANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHV- 317
DL+ + E K S +E+ Q+ Q+ S L V E+EK +
Sbjct: 951 ERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKV-ISEREKEIS 1009
Query: 318 ---NQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKN------QVQLGK 368
N+L + +E + K + L + EA + + + +L++ K QV+ +
Sbjct: 1010 GLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVE 1069
Query: 369 LEA--TIKSLSAELL----------------KANEIIKKLQG--DLKTLMGKLK----LK 404
LEA +K L ++ KA E + G ++K L KLK +
Sbjct: 1070 LEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMH 1129
Query: 405 NTVTIQQEK---LLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESK 461
+ ++ EK +LAE E LQK Q+ ++ ++K E K +Q++++ E+
Sbjct: 1130 TLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQEL 1189
Query: 462 QLLKNNEKLITWLNKE 477
+ L++ K I L +E
Sbjct: 1190 ERLRSENKDIENLRRE 1205
Score = 62.8 bits (151), Expect = 1e-09
Identities = 89/436 (20%), Positives = 187/436 (42%), Gaps = 98/436 (22%)
Query: 127 ETNPFKHLTHLSLKLLPGNDV---EIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFTRK 183
E N F++ H+S + + ++++ + + K+E L ++ + T QL+
Sbjct: 386 EHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLE---- 441
Query: 184 TLAEKKQELDKLRNEWASHTAALTNKHSQ------ELTNEKEKALQAQVQYQQ------- 230
+++ EL+KLR ++A LT K + + N ++ A Q +VQ Q+
Sbjct: 442 --SKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEE 499
Query: 231 ----------QHEQQKKDLE---ILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRE 277
+HE ++DL+ + + + L ++L++ + + L +R + + E
Sbjct: 500 VQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQ----LME 555
Query: 278 LKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQE----IKD 333
+ K EE LQ Q++L +N L + + + QT +VL +E I +
Sbjct: 556 SEQKRVNKEESLQMQVQDILE---QNEALKAQIQQFHSQI-AAQTSASVLAEELHKVIAE 611
Query: 334 KDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSA----------ELLKA 383
KD+ + +T+++ + +++ EE + Q L+A ++ L A EL K
Sbjct: 612 KDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKM 671
Query: 384 NEII-----------KKLQGDLKTLMGKLKLKNT-----------------------VTI 409
+ + ++LQ ++ M + K+ N V
Sbjct: 672 QQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVE 731
Query: 410 QQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEK 469
Q EK + EK+EKL+ ++ L+ + KE+E+ ++ + + K++++ K K N++
Sbjct: 732 QMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLK--AKQNDQ 789
Query: 470 -----LITWLNKELNE 480
L+ L K ++E
Sbjct: 790 VSFASLVEELKKVIHE 805
Score = 47.0 bits (110), Expect = 6e-05
Identities = 47/239 (19%), Positives = 97/239 (40%), Gaps = 17/239 (7%)
Query: 247 IHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTL 306
IHQLQ + L A +D K + +E+ + + R K + +L +E++
Sbjct: 331 IHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVF 390
Query: 307 DVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQL 366
+ H + Q+Q K + ++++ E + +ENG
Sbjct: 391 QNKIHVSYQETQQMQMKFQQVREQME----------------AEIAHLKQENGILRDAVS 434
Query: 367 GKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQ 426
SAEL K + +L +L GKL+ + E+ + + +LQ+ +
Sbjct: 435 NTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAE 494
Query: 427 KELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVR 485
+ ++V +R + E Q+ L++ E Q L +++ T ++K+ E +L++
Sbjct: 495 RRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSL-HSKLTDTLVSKQQLEQRLMQ 552
Score = 37.4 bits (85), Expect = 0.044
Identities = 38/209 (18%), Positives = 91/209 (43%), Gaps = 29/209 (13%)
Query: 161 KEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEK 220
++E+ +D++ K + + + +QEL++LR+E NK + L E+E
Sbjct: 1158 EQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSE---------NKDIENLRREREH 1208
Query: 221 A---LQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRE 277
L+ + + + ++L+ L + +L + SE N++L K + + T+ +
Sbjct: 1209 LEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTK 1268
Query: 278 LKAK----------LSGVEEELQRTKQEVLSLRRENSTLD-------VECHEKEKHVNQL 320
L+ + L ++ L+ + +++ + + ++ E EKE L
Sbjct: 1269 LRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSL 1328
Query: 321 QTKVAVLEQEIKDKDQLVLRTKEAFDTIQ 349
V L+Q ++ +Q + + KE + ++
Sbjct: 1329 NQTVTQLQQLLQAVNQQLTKEKEHYQVLE 1357
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 81.6 bits (200), Expect = 2e-15
Identities = 84/315 (26%), Positives = 152/315 (48%), Gaps = 29/315 (9%)
Query: 181 TRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKA-LQAQVQYQQQHEQQKKDL 239
T K +A K+E K+++E A A + +T KEK LQ QVQ + +
Sbjct: 851 TEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADA--- 907
Query: 240 EILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSL 299
++ QL +LEA K++TER + EL AK +E+E K+++ L
Sbjct: 908 ----EERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 963
Query: 300 RRENSTLDVECHEKEKHVNQLQTKVAVLEQEI----KDKDQLVLRTKEAFDTIQ--EQKV 353
+ ++ E H E V L ++A L++ I K+K L ++ D +Q E KV
Sbjct: 964 ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKV 1023
Query: 354 -VLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQE 412
L + K + Q+ LE +++ + +KL+GDLK L ++ + I+ E
Sbjct: 1024 NTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLK-----LAQESIMDIENE 1078
Query: 413 KLLAEKEEKLQKEQKELQDV------GQSLRIK-EQEVCKLQEQLEATVKKLEESKQLLK 465
K + +EKL+K++ E+ ++ Q+L I+ ++++ +LQ ++E +++E +
Sbjct: 1079 K--QQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRA 1136
Query: 466 NNEKLITWLNKELNE 480
EK + L++EL E
Sbjct: 1137 KAEKQRSDLSRELEE 1151
Score = 63.9 bits (154), Expect = 4e-10
Identities = 72/316 (22%), Positives = 144/316 (45%), Gaps = 42/316 (13%)
Query: 163 EKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALT--NKHSQELTNEKEK 220
+K L + K +D TLA+ ++E N+ + T + ++ +LT EK+
Sbjct: 945 KKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKA 1004
Query: 221 ALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKA 280
+A Q + ++ + L + I +L+ ++ +LE + + E+K + D + K
Sbjct: 1005 LQEAHQQTLDDLQAEEDKVNTLTKAKI-KLEQQVDDLEGSLEQ--EKKLRMD--LERAKR 1059
Query: 281 KLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLR 340
KL G +L+ ++ ++ + E LD + +KE ++ LQ+K I+D+ L ++
Sbjct: 1060 KLEG---DLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSK-------IEDEQALGIQ 1109
Query: 341 TKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGK 400
++ +Q + LEE E + K E LS EL + +E +++ G
Sbjct: 1110 LQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG-------- 1161
Query: 401 LKLKNTVTIQQEKLLAEKEEKLQKEQKELQD-------VGQSLRIKEQE-VCKLQEQ--- 449
T Q ++ ++E + QK +++L++ +LR K + V +L EQ
Sbjct: 1162 ------ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDN 1215
Query: 450 LEATVKKLEESKQLLK 465
L+ +KLE+ K +K
Sbjct: 1216 LQRVKQKLEKEKSEMK 1231
Score = 61.6 bits (148), Expect = 2e-09
Identities = 73/326 (22%), Positives = 142/326 (43%), Gaps = 22/326 (6%)
Query: 167 LMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQV 226
L + +D+ + K +E K E+D L + + + A N T E Q
Sbjct: 1209 LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED----QLSE 1264
Query: 227 QYQQQHEQQKKDLEILHQQNIHQLQN-----RLSELEAANKDLTERKYKGDSTIRELKAK 281
++ EQQ+ ++ Q+ Q ++ +L E EA L+ K I ELK +
Sbjct: 1265 LKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQ 1324
Query: 282 LSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRT 341
L + + S R + L + E+++ +LQ ++ E+ RT
Sbjct: 1325 LEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQ-----WRT 1379
Query: 342 KEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKL 401
K D IQ + LEE +K +L E +++++A+ + ++LQ +++ LM +
Sbjct: 1380 KYETDAIQRTEE-LEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDV 1438
Query: 402 KLKNTVTIQQEK-------LLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATV 454
+ N +K +LAE ++K ++ EL+ + R E+ K++ E ++
Sbjct: 1439 ERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESL 1498
Query: 455 KKLEESKQLLKNNEKLITWLNKELNE 480
+LE K+ KN ++ I+ L +++ E
Sbjct: 1499 DQLETLKRENKNLQQEISDLTEQIAE 1524
Score = 55.5 bits (132), Expect = 2e-07
Identities = 70/344 (20%), Positives = 150/344 (43%), Gaps = 45/344 (13%)
Query: 146 DVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNE---WASH 202
+++ K LA L+ S+ + D +Q + +++ AE ++ L K E W +
Sbjct: 1328 EIKAKNALAHALQSSRHD-------CDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380
Query: 203 TAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSEL----- 257
+ ++EL K+K Q ++Q ++H + ++ +LQN + +L
Sbjct: 1381 YETDAIQRTEELEEAKKKLAQ-RLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVE 1439
Query: 258 --EAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEK 315
AA L +++ D + E K K EL+ +++E SL E + E
Sbjct: 1440 RTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLD 1499
Query: 316 HVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKS 375
+ L+ + L+QEI D + + + +++ K +E+ + Q L + EA+++
Sbjct: 1500 QLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEH 1559
Query: 376 LSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQS 435
++L ++Q +L N V + ++ +AEK+E++ + ++
Sbjct: 1560 EEGKIL-------RIQLEL----------NQVKSEVDRKIAEKDEEIDQLKR------NH 1596
Query: 436 LRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELN 479
+RI E +Q L+A ++ ++ +L K E + + +LN
Sbjct: 1597 IRIVE----SMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLN 1636
Score = 51.2 bits (121), Expect = 3e-06
Identities = 66/353 (18%), Positives = 160/353 (45%), Gaps = 43/353 (12%)
Query: 165 LSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKE----- 219
L + L+ ++D + +AEK +E+D+L+ ++ + E+ + +
Sbjct: 1565 LRIQLELNQVKSEVD---RKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLK 1621
Query: 220 KALQA---QVQYQQQHEQQKKDLEILHQQN----IHQLQNRLSELEAANKDLTE------ 266
K ++ +++ Q H + + + +N + Q L + + +DL E
Sbjct: 1622 KKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVE 1681
Query: 267 -RKYKGDSTIRELKAKLSGVEEELQRTKQEVLS-------LRRENSTLDVECHEKEKHVN 318
R + I EL+A L E + +QE+L L +N++L + E ++
Sbjct: 1682 RRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDIS 1741
Query: 319 QLQTKVAVLEQEIKDKDQLVLRTKEAFD--TIQEQKVVLEENGEKNQVQLGK-LEATIKS 375
Q+Q ++ + QE ++ ++ + K+A + +++ E++ + ++ K +E T+K
Sbjct: 1742 QMQGEMEDILQEARNAEE---KAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKD 1798
Query: 376 LSAELLKANEI--------IKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQK 427
L L +A ++ I+KL+ ++ L G+++ + + K L + E ++++
Sbjct: 1799 LQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTY 1858
Query: 428 ELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNE 480
+ ++ +++ + V KLQ ++++ ++ EE+++ N L EL E
Sbjct: 1859 QTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEE 1911
Score = 49.7 bits (117), Expect = 9e-06
Identities = 50/254 (19%), Positives = 107/254 (42%), Gaps = 15/254 (5%)
Query: 209 KHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERK 268
K + + LQA+++ + +Q + + +Q + R+ L N L K
Sbjct: 1674 KEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTK 1733
Query: 269 YKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLE 328
K ++ I +++ ++ + +E + +++ + + + E +++ L+ +E
Sbjct: 1734 KKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 1793
Query: 329 QEIKD-------KDQLVLR-TKEAFDTIQEQKVVLEENGEKNQVQ-------LGKLEATI 373
Q +KD +QL L+ K+ ++ + LE E Q + L K E +
Sbjct: 1794 QTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRV 1853
Query: 374 KSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVG 433
K L+ + + + I +LQ + L K+K + E+ K +K Q EL++
Sbjct: 1854 KELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAE 1913
Query: 434 QSLRIKEQEVCKLQ 447
+ I E +V KL+
Sbjct: 1914 ERADIAESQVNKLR 1927
Score = 44.7 bits (104), Expect = 3e-04
Identities = 75/368 (20%), Positives = 145/368 (39%), Gaps = 52/368 (14%)
Query: 160 SKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKE 219
SK+ L+ S+D Q F + K L L A L + T +
Sbjct: 744 SKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITR-----TQARC 798
Query: 220 KALQAQVQYQQQHEQQKKDLEILHQQNIHQLQN-----------------RLSELEAANK 262
+ A+V+YQ+ E+++ I Q NI N + +E E
Sbjct: 799 RGFLARVEYQRMVERREAIFCI--QYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMA 856
Query: 263 DLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRE-----NSTLDVE--CHEKEK 315
+ E K + + +AK +EE++ +E L+ + D E C + K
Sbjct: 857 TMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIK 916
Query: 316 HVNQLQTKVAVLEQEIKDKD----QLVLRTKEAFDTIQE------------QKVVLEENG 359
QL+ K+ + + +D++ +L + ++ D E KV E++
Sbjct: 917 TKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHA 976
Query: 360 EKNQV-----QLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKL 414
+N+V ++ L+ TI L+ E E ++ DL+ K+ I+ E+
Sbjct: 977 TENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQ 1036
Query: 415 LAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWL 474
+ + E L++E+K D+ ++ R E ++ QE + + ++ + LK E I+ L
Sbjct: 1037 VDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNL 1096
Query: 475 NKELNENQ 482
++ + Q
Sbjct: 1097 QSKIEDEQ 1104
Score = 39.3 bits (90), Expect = 0.012
Identities = 40/171 (23%), Positives = 88/171 (51%), Gaps = 11/171 (6%)
Query: 319 QLQTKVAVLEQEI-KDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLS 377
+ + ++A +++E K KD+L +++ ++E+ V L + EKN +QL +++A + L+
Sbjct: 850 ETEKEMATMKEEFQKIKDELA-KSEAKRKELEEKMVTLLK--EKNDLQL-QVQAEAEGLA 905
Query: 378 AELLKANEIIK-KLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSL 436
+ +++IK K+Q L K+K +E++ AE K +K + E ++ + +
Sbjct: 906 DAEERCDQLIKTKIQ-----LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960
Query: 437 RIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQ 487
E + K++++ AT K++ + + ++ I L KE Q +Q
Sbjct: 961 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQ 1011
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 81.6 bits (200), Expect = 2e-15
Identities = 84/315 (26%), Positives = 152/315 (48%), Gaps = 29/315 (9%)
Query: 181 TRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKA-LQAQVQYQQQHEQQKKDL 239
T K +A K+E K+++E A A + +T KEK LQ QVQ + +
Sbjct: 851 TEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADA--- 907
Query: 240 EILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSL 299
++ QL +LEA K++TER + EL AK +E+E K+++ L
Sbjct: 908 ----EERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 963
Query: 300 RRENSTLDVECHEKEKHVNQLQTKVAVLEQEI----KDKDQLVLRTKEAFDTIQ--EQKV 353
+ ++ E H E V L ++A L++ I K+K L ++ D +Q E KV
Sbjct: 964 ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKV 1023
Query: 354 -VLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQE 412
L + K + Q+ LE +++ + +KL+GDLK L ++ + I+ E
Sbjct: 1024 NTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLK-----LAQESIMDIENE 1078
Query: 413 KLLAEKEEKLQKEQKELQDV------GQSLRIK-EQEVCKLQEQLEATVKKLEESKQLLK 465
K + +EKL+K++ E+ ++ Q+L I+ ++++ +LQ ++E +++E +
Sbjct: 1079 K--QQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRA 1136
Query: 466 NNEKLITWLNKELNE 480
EK + L++EL E
Sbjct: 1137 KAEKQRSDLSRELEE 1151
Score = 63.9 bits (154), Expect = 4e-10
Identities = 72/316 (22%), Positives = 144/316 (45%), Gaps = 42/316 (13%)
Query: 163 EKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALT--NKHSQELTNEKEK 220
+K L + K +D TLA+ ++E N+ + T + ++ +LT EK+
Sbjct: 945 KKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKA 1004
Query: 221 ALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKA 280
+A Q + ++ + L + I +L+ ++ +LE + + E+K + D + K
Sbjct: 1005 LQEAHQQTLDDLQAEEDKVNTLTKAKI-KLEQQVDDLEGSLEQ--EKKLRMD--LERAKR 1059
Query: 281 KLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLR 340
KL G +L+ ++ ++ + E LD + +KE ++ LQ+K I+D+ L ++
Sbjct: 1060 KLEG---DLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSK-------IEDEQALGIQ 1109
Query: 341 TKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGK 400
++ +Q + LEE E + K E LS EL + +E +++ G
Sbjct: 1110 LQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG-------- 1161
Query: 401 LKLKNTVTIQQEKLLAEKEEKLQKEQKELQD-------VGQSLRIKEQE-VCKLQEQ--- 449
T Q ++ ++E + QK +++L++ +LR K + V +L EQ
Sbjct: 1162 ------ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDN 1215
Query: 450 LEATVKKLEESKQLLK 465
L+ +KLE+ K +K
Sbjct: 1216 LQRVKQKLEKEKSEMK 1231
Score = 61.6 bits (148), Expect = 2e-09
Identities = 73/326 (22%), Positives = 142/326 (43%), Gaps = 22/326 (6%)
Query: 167 LMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQV 226
L + +D+ + K +E K E+D L + + + A N T E Q
Sbjct: 1209 LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED----QLSE 1264
Query: 227 QYQQQHEQQKKDLEILHQQNIHQLQN-----RLSELEAANKDLTERKYKGDSTIRELKAK 281
++ EQQ+ ++ Q+ Q ++ +L E EA L+ K I ELK +
Sbjct: 1265 LKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQ 1324
Query: 282 LSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRT 341
L + + S R + L + E+++ +LQ ++ E+ RT
Sbjct: 1325 LEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQ-----WRT 1379
Query: 342 KEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKL 401
K D IQ + LEE +K +L E +++++A+ + ++LQ +++ LM +
Sbjct: 1380 KYETDAIQRTEE-LEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDV 1438
Query: 402 KLKNTVTIQQEK-------LLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATV 454
+ N +K +LAE ++K ++ EL+ + R E+ K++ E ++
Sbjct: 1439 ERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESL 1498
Query: 455 KKLEESKQLLKNNEKLITWLNKELNE 480
+LE K+ KN ++ I+ L +++ E
Sbjct: 1499 DQLETLKRENKNLQQEISDLTEQIAE 1524
Score = 55.5 bits (132), Expect = 2e-07
Identities = 70/344 (20%), Positives = 150/344 (43%), Gaps = 45/344 (13%)
Query: 146 DVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNE---WASH 202
+++ K LA L+ S+ + D +Q + +++ AE ++ L K E W +
Sbjct: 1328 EIKAKNALAHALQSSRHD-------CDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380
Query: 203 TAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSEL----- 257
+ ++EL K+K Q ++Q ++H + ++ +LQN + +L
Sbjct: 1381 YETDAIQRTEELEEAKKKLAQ-RLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVE 1439
Query: 258 --EAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEK 315
AA L +++ D + E K K EL+ +++E SL E + E
Sbjct: 1440 RTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLD 1499
Query: 316 HVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKS 375
+ L+ + L+QEI D + + + +++ K +E+ + Q L + EA+++
Sbjct: 1500 QLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEH 1559
Query: 376 LSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQS 435
++L ++Q +L N V + ++ +AEK+E++ + ++
Sbjct: 1560 EEGKIL-------RIQLEL----------NQVKSEVDRKIAEKDEEIDQLKR------NH 1596
Query: 436 LRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELN 479
+RI E +Q L+A ++ ++ +L K E + + +LN
Sbjct: 1597 IRIVE----SMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLN 1636
Score = 51.2 bits (121), Expect = 3e-06
Identities = 66/353 (18%), Positives = 160/353 (45%), Gaps = 43/353 (12%)
Query: 165 LSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKE----- 219
L + L+ ++D + +AEK +E+D+L+ ++ + E+ + +
Sbjct: 1565 LRIQLELNQVKSEVD---RKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLK 1621
Query: 220 KALQA---QVQYQQQHEQQKKDLEILHQQN----IHQLQNRLSELEAANKDLTE------ 266
K ++ +++ Q H + + + +N + Q L + + +DL E
Sbjct: 1622 KKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVE 1681
Query: 267 -RKYKGDSTIRELKAKLSGVEEELQRTKQEVLS-------LRRENSTLDVECHEKEKHVN 318
R + I EL+A L E + +QE+L L +N++L + E ++
Sbjct: 1682 RRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDIS 1741
Query: 319 QLQTKVAVLEQEIKDKDQLVLRTKEAFD--TIQEQKVVLEENGEKNQVQLGK-LEATIKS 375
Q+Q ++ + QE ++ ++ + K+A + +++ E++ + ++ K +E T+K
Sbjct: 1742 QMQGEMEDILQEARNAEE---KAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKD 1798
Query: 376 LSAELLKANEI--------IKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQK 427
L L +A ++ I+KL+ ++ L G+++ + + K L + E ++++
Sbjct: 1799 LQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTY 1858
Query: 428 ELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNE 480
+ ++ +++ + V KLQ ++++ ++ EE+++ N L EL E
Sbjct: 1859 QTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEE 1911
Score = 49.7 bits (117), Expect = 9e-06
Identities = 50/254 (19%), Positives = 107/254 (42%), Gaps = 15/254 (5%)
Query: 209 KHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERK 268
K + + LQA+++ + +Q + + +Q + R+ L N L K
Sbjct: 1674 KEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTK 1733
Query: 269 YKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLE 328
K ++ I +++ ++ + +E + +++ + + + E +++ L+ +E
Sbjct: 1734 KKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 1793
Query: 329 QEIKD-------KDQLVLR-TKEAFDTIQEQKVVLEENGEKNQVQ-------LGKLEATI 373
Q +KD +QL L+ K+ ++ + LE E Q + L K E +
Sbjct: 1794 QTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRV 1853
Query: 374 KSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVG 433
K L+ + + + I +LQ + L K+K + E+ K +K Q EL++
Sbjct: 1854 KELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAE 1913
Query: 434 QSLRIKEQEVCKLQ 447
+ I E +V KL+
Sbjct: 1914 ERADIAESQVNKLR 1927
Score = 44.7 bits (104), Expect = 3e-04
Identities = 75/368 (20%), Positives = 145/368 (39%), Gaps = 52/368 (14%)
Query: 160 SKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKE 219
SK+ L+ S+D Q F + K L L A L + T +
Sbjct: 744 SKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITR-----TQARC 798
Query: 220 KALQAQVQYQQQHEQQKKDLEILHQQNIHQLQN-----------------RLSELEAANK 262
+ A+V+YQ+ E+++ I Q NI N + +E E
Sbjct: 799 RGFLARVEYQRMVERREAIFCI--QYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMA 856
Query: 263 DLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRE-----NSTLDVE--CHEKEK 315
+ E K + + +AK +EE++ +E L+ + D E C + K
Sbjct: 857 TMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIK 916
Query: 316 HVNQLQTKVAVLEQEIKDKD----QLVLRTKEAFDTIQE------------QKVVLEENG 359
QL+ K+ + + +D++ +L + ++ D E KV E++
Sbjct: 917 TKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHA 976
Query: 360 EKNQV-----QLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKL 414
+N+V ++ L+ TI L+ E E ++ DL+ K+ I+ E+
Sbjct: 977 TENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQ 1036
Query: 415 LAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWL 474
+ + E L++E+K D+ ++ R E ++ QE + + ++ + LK E I+ L
Sbjct: 1037 VDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNL 1096
Query: 475 NKELNENQ 482
++ + Q
Sbjct: 1097 QSKIEDEQ 1104
Score = 39.3 bits (90), Expect = 0.012
Identities = 40/171 (23%), Positives = 88/171 (51%), Gaps = 11/171 (6%)
Query: 319 QLQTKVAVLEQEI-KDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLS 377
+ + ++A +++E K KD+L +++ ++E+ V L + EKN +QL +++A + L+
Sbjct: 850 ETEKEMATMKEEFQKIKDELA-KSEAKRKELEEKMVTLLK--EKNDLQL-QVQAEAEGLA 905
Query: 378 AELLKANEIIK-KLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSL 436
+ +++IK K+Q L K+K +E++ AE K +K + E ++ + +
Sbjct: 906 DAEERCDQLIKTKIQ-----LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960
Query: 437 RIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQ 487
E + K++++ AT K++ + + ++ I L KE Q +Q
Sbjct: 961 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQ 1011
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 81.3 bits (199), Expect = 3e-15
Identities = 80/316 (25%), Positives = 154/316 (48%), Gaps = 31/316 (9%)
Query: 181 TRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLE 240
T K +A K+E +++ T + +EL + LQ + Q Q + ++ +L
Sbjct: 847 TEKEMATMKEEFGRIKE-----TLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLN 901
Query: 241 ILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLR 300
++ ++N++ +LEA K++ ER + EL AK +E+E K+++ L
Sbjct: 902 DAEERCDQLIKNKI-QLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLE 960
Query: 301 RENSTLDVECHEKEKHVNQLQTKVAVLEQEI----KDKDQLVLRTKEAFDTIQ--EQKV- 353
+ ++ E H E V L ++A L++ I K+K L ++A D +Q E KV
Sbjct: 961 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVN 1020
Query: 354 VLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEK 413
L ++ K + Q+ LE +++ + +KL+GDLK L ++ + ++ +K
Sbjct: 1021 SLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK-----LTQESIMDLENDK 1075
Query: 414 LLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQ---------LEATVKKLEESKQLL 464
L + EEKL+K++ ++ Q+ +I++++V LQ Q +E ++LE +
Sbjct: 1076 L--QLEEKLKKKEFDINQ--QNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTAR 1131
Query: 465 KNNEKLITWLNKELNE 480
EKL + L++EL E
Sbjct: 1132 AKVEKLRSDLSRELEE 1147
Score = 77.0 bits (188), Expect = 5e-14
Identities = 82/382 (21%), Positives = 158/382 (41%), Gaps = 56/382 (14%)
Query: 157 LKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTN 216
L+ K E +L + + D T+QL K + E ++ +L E +AL + L +
Sbjct: 1497 LETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEAS-LEH 1555
Query: 217 EKEKALQAQVQYQQ----------QHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTE 266
E+ K L+AQ+++ Q + +++ + + HQ+ + LQ L + ++
Sbjct: 1556 EEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLR 1615
Query: 267 RKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLR-------------------------- 300
K K + + E++ +LS +++V SL+
Sbjct: 1616 VKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAI 1675
Query: 301 --RENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEEN 358
R N+ L E E V Q + + EQE+ + T E + Q L
Sbjct: 1676 VERRNNLLQAELEELRAVVEQTERSRKLAEQEL-------IETSERVQLLHSQNTSLINQ 1728
Query: 359 GEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEK 418
+K + L +L++ ++ E A E KK D + +LK + + E++
Sbjct: 1729 KKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNM 1788
Query: 419 EEKLQKEQKELQDVGQ--------SLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKL 470
E+ ++ Q L + Q L+ E V +L+ +LEA K+ ES + ++ +E+
Sbjct: 1789 EQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERR 1848
Query: 471 ITWLNKELNENQ--LVRKQDVL 490
I L + E++ L+R QD++
Sbjct: 1849 IKELTYQTEEDKKNLLRLQDLV 1870
Score = 69.7 bits (169), Expect = 8e-12
Identities = 66/357 (18%), Positives = 160/357 (44%), Gaps = 44/357 (12%)
Query: 161 KEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQEL-TNEKE 219
+E+ +SL+Q +D Q+ + L + ++ D+L + NK E E
Sbjct: 876 EEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQL----------IKNKIQLEAKVKEMN 925
Query: 220 KALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELK 279
+ L+ + + + +K+ LE +L+ + +LE + + K+ ++ ++ L
Sbjct: 926 ERLEDEEEMNAELTAKKRKLE----DECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 981
Query: 280 AKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVL 339
+++G++E + + +E +L+ + + +E VN L LEQ++ D + +
Sbjct: 982 EEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLE 1041
Query: 340 R---------------------TKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSA 378
+ T+E+ ++ K+ LEE +K + + + + I+
Sbjct: 1042 QEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQV 1101
Query: 379 ELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRI 438
L+ + +K+ Q ++ L +L+ + T + EKL ++ +L++ + L++ G + +
Sbjct: 1102 LALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSV 1161
Query: 439 -------KEQEVCKLQEQL-EATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQ 487
+E E K++ L EAT++ + L K + + L ++++ Q V+++
Sbjct: 1162 QIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQK 1218
Score = 68.9 bits (167), Expect = 1e-11
Identities = 78/341 (22%), Positives = 148/341 (43%), Gaps = 32/341 (9%)
Query: 173 DATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELT-----NEKEKALQAQV- 226
D+ +L L KQ+L+K ++E+ +T+ Q + + + L+ Q
Sbjct: 1200 DSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQAN 1259
Query: 227 QYQQQHEQQKKDLEILHQQNIH------QLQNRLSELEAANKDLTERKYKGDSTIRELKA 280
+Y+ + E+ ++ L Q +L +L E EA LT K + +LK
Sbjct: 1260 EYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKR 1319
Query: 281 KLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLR 340
+L + + S R + L + E+ + +LQ ++ E+ R
Sbjct: 1320 QLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQ-----WR 1374
Query: 341 TKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGK 400
TK D IQ + LEE +K +L E +++++A+ + +LQ +++ LM
Sbjct: 1375 TKYETDAIQRTEE-LEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 1433
Query: 401 LKLKNTVTIQQEK-------LLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEAT 453
++ N +K +LAE ++K ++ Q EL+ + R E+ KL+ E +
Sbjct: 1434 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEES 1493
Query: 454 VKKLEESKQLLKNNEKLITWLNKELNEN-------QLVRKQ 487
++ LE K+ KN ++ I+ L ++L E + VRKQ
Sbjct: 1494 LEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQ 1534
Score = 67.0 bits (162), Expect = 5e-11
Identities = 67/338 (19%), Positives = 156/338 (46%), Gaps = 23/338 (6%)
Query: 161 KEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAAL--TNKHSQELTNEK 218
+E K L Q L DA + ++ + ++ +L+NE + +N + L ++
Sbjct: 1389 EEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQ 1448
Query: 219 EKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIREL 278
+ +++Q++E+ + +LE Q+ L L +L+ A ++ E + L
Sbjct: 1449 RNFDKILAEWKQKYEESQSELES-SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNL 1507
Query: 279 KAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLV 338
+ ++S + E+L + V L + L+VE E LQ+ + E ++ ++ +
Sbjct: 1508 QEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLE-------LQSALEEAEASLEHEEGKI 1560
Query: 339 LRTKEAFDTIQEQ--KVVLEENGEKNQVQLGK---LEATIKSLSAELLKANEII---KKL 390
LR + F+ I+ + + + E++ E Q + +++ SL AE NE++ KK+
Sbjct: 1561 LRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKM 1620
Query: 391 QGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQL 450
+GDL + +L N + + +K + + L+ Q +L D ++ ++ + ++ +
Sbjct: 1621 EGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRN 1680
Query: 451 EATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQD 488
+LEE + +++ E+ +++L E +L+ +
Sbjct: 1681 NLLQAELEELRAVVEQTER-----SRKLAEQELIETSE 1713
Score = 53.9 bits (128), Expect = 5e-07
Identities = 67/333 (20%), Positives = 141/333 (42%), Gaps = 58/333 (17%)
Query: 164 KLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTN--------KHSQELT 215
K + L++ QL + AE ++++ L++ L + K + +
Sbjct: 1617 KKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIV 1676
Query: 216 NEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTI 275
+ LQA+++ + +Q + L +Q + + R+ L + N L +K K +S +
Sbjct: 1677 ERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDL 1736
Query: 276 RELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKD 335
+L+ S VEE +Q EC E+ + T A++ +E+K +
Sbjct: 1737 TQLQ---SEVEEAVQ------------------ECRNAEEKAKKAITDAAMMAEELKKE- 1774
Query: 336 QLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEI--------I 387
Q+ LE +KN +E TIK L L +A +I +
Sbjct: 1775 -------------QDTSAHLERM-KKN------MEQTIKDLQHRLDEAEQIALKGGKKQL 1814
Query: 388 KKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQ 447
+KL+ ++ L G+L+ + + K + + E ++++ + ++ ++L + V KLQ
Sbjct: 1815 QKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQ 1874
Query: 448 EQLEATVKKLEESKQLLKNNEKLITWLNKELNE 480
+++A ++ EE+++ N + EL+E
Sbjct: 1875 LKVKAYKRQAEEAEEQANTNLSKFRKVQHELDE 1907
Score = 52.4 bits (124), Expect = 1e-06
Identities = 77/344 (22%), Positives = 145/344 (42%), Gaps = 52/344 (15%)
Query: 135 THLSLKLLPGNDV-EIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELD 193
T L + N+V +KK + G L + + + +A KQ+ + L + + +LD
Sbjct: 1601 TSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLD 1660
Query: 194 KL--RNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQ 251
N+ A+ + + L E E+ L+A V+ Q E+ +K L +Q + +
Sbjct: 1661 DAVRANDDLKENIAIVERRNNLLQAELEE-LRAVVE---QTERSRK----LAEQELIETS 1712
Query: 252 NRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECH 311
R+ L + N L +K K +S + +L++++ +E + +++ + + + E
Sbjct: 1713 ERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELK 1772
Query: 312 EKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEA 371
+++ L+ +EQ IKD + E + + + G+K QL KLEA
Sbjct: 1773 KEQDTSAHLERMKKNMEQTIKDLQH----------RLDEAEQIALKGGKK---QLQKLEA 1819
Query: 372 TIKSLSAEL--------------LKANEIIKKLQGD----------LKTLMGKLKLKNTV 407
++ L EL K+ IK+L L+ L+ KL+LK
Sbjct: 1820 RVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKA 1879
Query: 408 TIQQEKLLAEKEE----KLQKEQKELQDVGQSLRIKEQEVCKLQ 447
+Q + E+ K +K Q EL + + I E +V KL+
Sbjct: 1880 YKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLR 1923
Score = 52.0 bits (123), Expect = 2e-06
Identities = 80/372 (21%), Positives = 151/372 (40%), Gaps = 82/372 (22%)
Query: 163 EKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHS--QELTNEKEK 220
+K L + K +D TLA+ ++E N+ + T + +LT EK K
Sbjct: 941 KKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEK-K 999
Query: 221 ALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLT---ERKYKGDSTIRE 277
ALQ + H+Q DL++ + ++ L +LE DL E++ K +
Sbjct: 1000 ALQ------EAHQQALDDLQV-EEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLER 1052
Query: 278 LKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVA-------VLEQE 330
K KL G +L+ T++ ++ L + L+ + +KE +NQ +K+ L+++
Sbjct: 1053 AKRKLEG---DLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKK 1109
Query: 331 IKDKDQLVLRTKEAFDT------------------IQEQKVVLEENGEKNQVQLG----- 367
+K+ + +E + ++E LEE G VQ+
Sbjct: 1110 LKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR 1169
Query: 368 ----------------KLEATIKSLS-------AELLKANEIIKKLQGDLKTLMGKLKLK 404
+ EAT +L AEL + + +++++ L+ + KL+
Sbjct: 1170 EAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 1229
Query: 405 -NTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEV-----------CKLQEQLEA 452
+ VT E+++ K L+K + L+D R+K +E KLQ +
Sbjct: 1230 LDDVTSNMEQIIKAKAN-LEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGE 1288
Query: 453 TVKKLEESKQLL 464
++LEE + L+
Sbjct: 1289 LARQLEEKEALI 1300
Score = 48.1 bits (113), Expect = 3e-05
Identities = 47/216 (21%), Positives = 102/216 (47%), Gaps = 22/216 (10%)
Query: 278 LKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQL 337
+K L E + +++++SL +E + L ++ ++ ++N + + +Q IK+K QL
Sbjct: 861 IKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERC---DQLIKNKIQL 917
Query: 338 VLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTL 397
+ KE + +++++ + E K + KLE L ++ + K++ +
Sbjct: 918 EAKVKEMNERLEDEEEMNAELTAKKR----KLEDECSELKKDIDDLELTLAKVEKEKHAT 973
Query: 398 MGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQS----LRIKEQEV-------CKL 446
K+K ++++A KL KE+K LQ+ Q L+++E +V KL
Sbjct: 974 ENKVKNLTEEMAGLDEIIA----KLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKL 1029
Query: 447 QEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQ 482
++Q++ LE+ K++ + E+ L +L Q
Sbjct: 1030 EQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQ 1065
Score = 42.4 bits (98), Expect = 0.001
Identities = 42/171 (24%), Positives = 83/171 (48%), Gaps = 12/171 (7%)
Query: 323 KVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEEN-----GEKNQVQLGKLEATIKSLS 377
K A E+E+ + R KE + + ++ LEE EKN +QL +++A +L+
Sbjct: 843 KSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQL-QVQAEQDNLN 901
Query: 378 AELLKANEIIK-KLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSL 436
+ +++IK K+Q L K+K N +E++ AE K +K + E ++ + +
Sbjct: 902 DAEERCDQLIKNKIQ-----LEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDI 956
Query: 437 RIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQ 487
E + K++++ AT K++ + + +++I L KE Q +Q
Sbjct: 957 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1007
Score = 30.0 bits (66), Expect = 7.1
Identities = 51/229 (22%), Positives = 94/229 (41%), Gaps = 26/229 (11%)
Query: 263 DLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQT 322
D+ +YK T KA L G+ EE++ + + R Q Q
Sbjct: 752 DIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRM-----------------QAQA 794
Query: 323 KVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSL--SAEL 380
+ ++ E K ++ ++A IQ + G KN + KL IK L SAE
Sbjct: 795 RGQLMRIEFKK----IVERRDALLVIQWN--IRAFMGVKNWPWM-KLYFKIKPLLKSAET 847
Query: 381 LKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKE 440
K +K+ G +K + K + + ++ L +++ LQ + + QD +
Sbjct: 848 EKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERC 907
Query: 441 QEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQDV 489
++ K + QLEA VK++ E + + +T ++L + K+D+
Sbjct: 908 DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDI 956
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 80.1 bits (196), Expect = 6e-15
Identities = 85/317 (26%), Positives = 151/317 (47%), Gaps = 33/317 (10%)
Query: 181 TRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKA-LQAQVQYQQQHEQQKKDL 239
T K +A K+E +K + E A A + +T +EK LQ QVQ +
Sbjct: 849 TEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADA--- 905
Query: 240 EILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSL 299
++ QL +LEA K++TER + EL AK +E+E K+++ L
Sbjct: 906 ----EERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 961
Query: 300 RRENSTLDVECHEKEKHVNQLQTKVAVLEQEI----KDKDQLVLRTKEAFDTIQ--EQKV 353
+ ++ E H E V L ++A L++ I K+K L ++ D +Q E KV
Sbjct: 962 ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKV 1021
Query: 354 -VLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQE 412
L + K + Q+ LE +++ + +KL+GDLK L ++T+ I+ +
Sbjct: 1022 NTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLK-----LAQESTMDIEND 1076
Query: 413 KLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQ-----EQLEATVKKLEESKQLLKNN 467
K + +EKL+K KE + G +I++++ +Q ++L+A +++LEE + + +
Sbjct: 1077 K--QQLDEKLKK--KEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERAS 1132
Query: 468 ----EKLITWLNKELNE 480
EK + L++EL E
Sbjct: 1133 RAKAEKQRSDLSRELEE 1149
Score = 65.1 bits (157), Expect = 2e-10
Identities = 74/352 (21%), Positives = 166/352 (47%), Gaps = 34/352 (9%)
Query: 161 KEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTN--EK 218
+E+ ++LMQ +D Q+ +LA+ ++ D+L T +E+T E
Sbjct: 878 EEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQL-----IKTKIQLEAKIKEVTERAED 932
Query: 219 EKALQAQV-----QYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDS 273
E+ + A++ + + + + KKD++ L + + +++ E K+LTE D
Sbjct: 933 EEEINAELTAKKRKLEDECSELKKDIDDL-ELTLAKVEKEKHATENKVKNLTEEMAGLDE 991
Query: 274 TIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKD 333
TI +L + ++E Q+T ++ + + +TL + E+ V+ L+ LEQE K
Sbjct: 992 TIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLE---GSLEQEKKI 1048
Query: 334 KDQL----------VLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKA 383
+ L + +E+ I+ K L+E +K + ++ L++ I+ A ++
Sbjct: 1049 RMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQL 1108
Query: 384 NEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVG-------QSL 436
+ IK+LQ ++ L +++ + + EK ++ +L++ + L++ G +
Sbjct: 1109 QKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMN 1168
Query: 437 RIKEQEVCKLQEQL-EATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQ 487
+ +E E K++ L EAT++ + L K + + L ++++ Q V+++
Sbjct: 1169 KKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK 1220
Score = 61.2 bits (147), Expect = 3e-09
Identities = 80/338 (23%), Positives = 150/338 (44%), Gaps = 43/338 (12%)
Query: 157 LKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTN 216
+K +EE+ L+ L +L + + E D L ++ + A T + +EL
Sbjct: 1263 IKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQ-IEELKR 1321
Query: 217 EKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIR 276
+ E+ ++A+ + + D ++L +Q E + A +L K +S +
Sbjct: 1322 QLEEEIKAKSALAHALQSSRHDCDLLREQ--------YEEEQEAKAELQRAMSKANSEVA 1373
Query: 277 ELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQ------- 329
+ + K + +QRT++ L L + E+HV + K A LE+
Sbjct: 1374 QWRTKYE--TDAIQRTEE----LEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQN 1427
Query: 330 EIKDKDQLVLRTKEAFDTIQEQK----VVLEENGEKNQVQLGKLEATIK---SLSAELLK 382
E++D V RT A + +++ +L E +K + +LEA+ K SLS EL K
Sbjct: 1428 EVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFK 1487
Query: 383 ANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQE 442
++ L+TL K + KN +QQE +++ E++ + K + ++ + + EQE
Sbjct: 1488 IKNAYEESLDQLETL--KRENKN---LQQE--ISDLTEQIAEGGKRIHELEKIKKQVEQE 1540
Query: 443 VCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNE 480
+LQ LE E++ L++ E I + ELN+
Sbjct: 1541 KSELQAALE-------EAEASLEHEEGKILRIQLELNQ 1571
Score = 60.1 bits (144), Expect = 6e-09
Identities = 71/316 (22%), Positives = 143/316 (45%), Gaps = 42/316 (13%)
Query: 163 EKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALT--NKHSQELTNEKEK 220
+K L + K +D TLA+ ++E N+ + T + ++ +LT EK+
Sbjct: 943 KKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKA 1002
Query: 221 ALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKA 280
+A Q + ++ + L + I +L+ ++ +LE + + E+K + D + K
Sbjct: 1003 LQEAHQQTLDDLQAEEDKVNTLTKAKI-KLEQQVDDLEGSLEQ--EKKIRMD--LERAKR 1057
Query: 281 KLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLR 340
KL G +L+ ++ + + + LD + +KE ++ LQ+K I+D+ L ++
Sbjct: 1058 KLEG---DLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSK-------IEDEQALGMQ 1107
Query: 341 TKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGK 400
++ +Q + LEE E + K E LS EL + +E +++ G
Sbjct: 1108 LQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG-------- 1159
Query: 401 LKLKNTVTIQQEKLLAEKEEKLQKEQKELQD-------VGQSLRIKEQE-VCKLQEQ--- 449
T Q ++ ++E + QK +++L++ +LR K + V +L EQ
Sbjct: 1160 ------ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDN 1213
Query: 450 LEATVKKLEESKQLLK 465
L+ +KLE+ K +K
Sbjct: 1214 LQRVKQKLEKEKSEMK 1229
Score = 59.7 bits (143), Expect = 8e-09
Identities = 74/331 (22%), Positives = 149/331 (45%), Gaps = 32/331 (9%)
Query: 167 LMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQV 226
L + +D+ + K +E K E+D L + + + A N + +AL+ Q+
Sbjct: 1207 LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGN------LEKMCRALEDQL 1260
Query: 227 -QYQQQHEQQKKDLEILHQQNIH------QLQNRLSELEAANKDLTERKYKGDSTIRELK 279
+ + + E+Q++ + L Q + +L E + L+ K I ELK
Sbjct: 1261 SEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELK 1320
Query: 280 AKLSGVEEELQRTKQEVLSLRRENSTLDV--ECHEKEKHVN-QLQTKVAVLEQEIKDKDQ 336
+L EEE++ +L+ D+ E +E+E+ +LQ ++ E+
Sbjct: 1321 RQL---EEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQ--- 1374
Query: 337 LVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKT 396
RTK D IQ + LEE +K +L E +++++A+ + ++LQ +++
Sbjct: 1375 --WRTKYETDAIQRTEE-LEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVED 1431
Query: 397 LMGKLKLKNTVTIQQEK-------LLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQ 449
LM ++ N +K +LAE ++K ++ EL+ + R E+ K++
Sbjct: 1432 LMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNA 1491
Query: 450 LEATVKKLEESKQLLKNNEKLITWLNKELNE 480
E ++ +LE K+ KN ++ I+ L +++ E
Sbjct: 1492 YEESLDQLETLKRENKNLQQEISDLTEQIAE 1522
Score = 57.0 bits (136), Expect = 5e-08
Identities = 66/332 (19%), Positives = 144/332 (43%), Gaps = 43/332 (12%)
Query: 164 KLSLMQSLDDATKQLDFTRKTLAEK---KQELDKLRNEWASHTAALTNKHSQELTNEKEK 220
K +L +L + D R+ E+ K EL + ++ S A K+ + E+
Sbjct: 1330 KSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEE 1389
Query: 221 ALQAQVQYQQQHEQQKKDLEILH------QQNIHQLQNRLSEL-------EAANKDLTER 267
+A+ + Q+ + ++ +E ++ ++ +LQN + +L AA L ++
Sbjct: 1390 LEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKK 1449
Query: 268 KYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVL 327
+ D + E K K EL+ +++E SL E + E + L+ + L
Sbjct: 1450 QRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNL 1509
Query: 328 EQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEII 387
+QEI D + + + +++ K +E+ + Q L + EA+++ ++L
Sbjct: 1510 QQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKIL------ 1563
Query: 388 KKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQ 447
++Q +L N V + ++ +AEK+E++ + ++ +RI E +Q
Sbjct: 1564 -RIQLEL----------NQVKSEVDRKIAEKDEEIDQMKR------NHIRIVE----SMQ 1602
Query: 448 EQLEATVKKLEESKQLLKNNEKLITWLNKELN 479
L+A ++ ++ +L K E + + +LN
Sbjct: 1603 STLDAEIRSRNDAIRLKKKMEGDLNEMEIQLN 1634
Score = 56.2 bits (134), Expect = 9e-08
Identities = 63/289 (21%), Positives = 127/289 (43%), Gaps = 32/289 (11%)
Query: 204 AALTNKHSQELTNEKEKALQAQVQYQ-QQHEQQKKDLEILHQQNIHQLQNRLSELEAANK 262
+A T K + E EK + + + ++ E ++K + ++ ++N QLQ ++A
Sbjct: 846 SAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQ-----VQAEAD 900
Query: 263 DLTERKYKGDSTIR---ELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQ 319
L + + + D I+ +L+AK+ V E + ++ L + L+ EC E +K ++
Sbjct: 901 SLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 960
Query: 320 LQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQ-LGKLEATIKSLSA 378
L+ +A +E+E K A EN KN + + L+ TI L+
Sbjct: 961 LELTLAKVEKE-----------KHA-----------TENKVKNLTEEMAGLDETIAKLTK 998
Query: 379 ELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRI 438
E E ++ DL+ K+ I+ E+ + + E L++E+K D+ ++ R
Sbjct: 999 EKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRK 1058
Query: 439 KEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQ 487
E ++ QE ++ + LK E ++ L ++ + Q + Q
Sbjct: 1059 LEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQ 1107
Score = 52.0 bits (123), Expect = 2e-06
Identities = 66/353 (18%), Positives = 161/353 (45%), Gaps = 43/353 (12%)
Query: 165 LSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKE----- 219
L + L+ ++D + +AEK +E+D+++ ++ + E+ + +
Sbjct: 1563 LRIQLELNQVKSEVD---RKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLK 1619
Query: 220 KALQA---QVQYQQQHEQQKKDLEILHQQNIHQL----QNRLSELEAANKDLTE------ 266
K ++ +++ Q H + + + +N + Q L + + +DL E
Sbjct: 1620 KKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVE 1679
Query: 267 -RKYKGDSTIRELKAKLSGVEEELQRTKQEVLS-------LRRENSTLDVECHEKEKHVN 318
R + I EL+A L E + +QE+L L +N++L + E ++
Sbjct: 1680 RRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDIS 1739
Query: 319 QLQTKVAVLEQEIKDKDQLVLRTKEAFD--TIQEQKVVLEENGEKNQVQLGK-LEATIKS 375
Q+Q ++ + QE ++ ++ + K+A + +++ E++ + ++ K LE T+K
Sbjct: 1740 QIQGEMEDIIQEARNAEE---KAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKD 1796
Query: 376 LSAELLKANEI--------IKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQK 427
L L +A ++ I+KL+ ++ L G+++ + ++ K L + E K+++
Sbjct: 1797 LQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTY 1856
Query: 428 ELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNE 480
+ ++ +++ + V KLQ ++++ ++ EE+++ N + EL E
Sbjct: 1857 QTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEE 1909
Score = 50.1 bits (118), Expect = 7e-06
Identities = 51/254 (20%), Positives = 110/254 (43%), Gaps = 15/254 (5%)
Query: 209 KHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERK 268
K + + LQA+++ + +Q + + +Q + R+ L N L K
Sbjct: 1672 KEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTK 1731
Query: 269 YKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLE 328
K ++ I +++ ++ + +E + +++ + + + E +++ L+ LE
Sbjct: 1732 KKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLE 1791
Query: 329 QEIKD-------KDQLVLR-TKEAFDTIQEQKVVLE---ENGEKNQVQ----LGKLEATI 373
Q +KD +QL L+ K+ ++ + LE E+ +K V+ L K E +
Sbjct: 1792 QTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKV 1851
Query: 374 KSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVG 433
K L+ + + + I +LQ + L K+K + E+ K ++ Q EL++
Sbjct: 1852 KELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAE 1911
Query: 434 QSLRIKEQEVCKLQ 447
+ I E +V KL+
Sbjct: 1912 ERADIAESQVNKLR 1925
Score = 42.0 bits (97), Expect = 0.002
Identities = 42/171 (24%), Positives = 82/171 (47%), Gaps = 12/171 (7%)
Query: 323 KVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEEN-----GEKNQVQLGKLEATIKSLS 377
K A E+E+ + + +TKE + ++ LEE EKN +QL +++A SL+
Sbjct: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQL-QVQAEADSLA 903
Query: 378 AELLKANEIIK-KLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSL 436
+ +++IK K+Q L K+K +E++ AE K +K + E ++ + +
Sbjct: 904 DAEERCDQLIKTKIQ-----LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 958
Query: 437 RIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQ 487
E + K++++ AT K++ + + ++ I L KE Q +Q
Sbjct: 959 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQ 1009
Score = 40.8 bits (94), Expect = 0.004
Identities = 48/214 (22%), Positives = 95/214 (44%), Gaps = 29/214 (13%)
Query: 281 KLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLR 340
K + E+E+ K+E + E + + + E E+ + L + L+ +++ + +
Sbjct: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLAD 904
Query: 341 TKEAFDTIQEQKVVLE-------ENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGD 393
+E D + + K+ LE E E + +L A + L E + +KK D
Sbjct: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE----LKKDIDD 960
Query: 394 LKTLMGKLKLKNTVTIQQEKLLAEKE-------EKLQKEQKELQDVGQ----SLRIKEQE 442
L+ + K++ + T + K L E+ KL KE+K LQ+ Q L+ +E +
Sbjct: 961 LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK 1020
Query: 443 V-------CKLQEQLEATVKKLEESKQLLKNNEK 469
V KL++Q++ LE+ K++ + E+
Sbjct: 1021 VNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLER 1054
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 79.7 bits (195), Expect = 8e-15
Identities = 64/338 (18%), Positives = 170/338 (50%), Gaps = 17/338 (5%)
Query: 161 KEEKLSLMQSLDDATKQLDFTRKTLAEK---KQELDKLRNEWASHTAALTNKHSQELTNE 217
+EEK + + + K+ + K ++ +++ +K+R + H QE E
Sbjct: 409 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE 468
Query: 218 KEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRE 277
+EK Q+Q E +++ +I Q+ I + + ++ E E + E+ ++ + IRE
Sbjct: 469 EEKR-------QEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIRE 521
Query: 278 LKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEK-----HVNQLQTKVAVLEQEIK 332
+ K+ EE++ R ++++ + E + + HE+EK + + K+ E++I+
Sbjct: 522 QEEKIREQEEKMWRQEEKIRE-QEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIR 580
Query: 333 DKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQG 392
++++ V R +E +E++ EE K + ++ + E I+ ++ + E I++ +
Sbjct: 581 EQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEE 640
Query: 393 DLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEA 452
+ K+ + +QE+ + E+EE + ++++++++ + +R +E+++ + +E ++
Sbjct: 641 MTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQE 700
Query: 453 TVKKL-EESKQLLKNNEKLITWLNKELNENQLVRKQDV 489
+K+ E+ +++ + EK+ K + + + +Q+V
Sbjct: 701 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738
Score = 73.9 bits (180), Expect = 4e-13
Identities = 65/299 (21%), Positives = 146/299 (48%), Gaps = 29/299 (9%)
Query: 194 KLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILH------QQNI 247
K+ N T HS E +E++ + Q Q +++ E Q + IL Q +
Sbjct: 89 KINNGTNPETTTSGGCHSPE--DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMAL 146
Query: 248 HQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLD 307
+ Q+ + +LE +DL R + EL+ LS V + ++ + + L +E L
Sbjct: 147 YYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALS 206
Query: 308 VECHEKEKHVNQLQTKVAVLEQEIK----DKDQLVLRTKEAFDTIQEQKVVLEENGEKNQ 363
+E + +L+ K A L+++++ +K ++ L KE ++ K++L + ++ Q
Sbjct: 207 LELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ--QQLQ 264
Query: 364 VQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQ 423
+ L ++S+SA KLQ ++ + +L N + QQE+ + +EEK+Q
Sbjct: 265 AEADHLGKELQSVSA----------KLQAQVE----ENELWNRLNQQQEEKMWRQEEKIQ 310
Query: 424 KEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQ 482
+ ++++Q+ + +R +E+++ + +E++ + + E ++ ++ E+++ W +E Q
Sbjct: 311 EWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM-WEKEEKMRRQ 368
Score = 72.4 bits (176), Expect = 1e-12
Identities = 62/329 (18%), Positives = 170/329 (51%), Gaps = 23/329 (6%)
Query: 161 KEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEK 220
KEEK+ + L++ + + R+ EK+QE +K+R + + ++ ++EK
Sbjct: 389 KEEKI---RELEEKMHEQEKIREQ-EEKRQEEEKIREQ------EKRQEQEAKMWRQEEK 438
Query: 221 ALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKA 280
+ + + ++Q ++ + E +H+Q + + + E E + E K I K
Sbjct: 439 IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ--EEKIHEQEEIWRQKE 496
Query: 281 KLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLR 340
K+ EE+++ KQE R+E + E+E+ + + + K+ E++I++++++
Sbjct: 497 KMHEQEEKIR--KQEEKVWRQEE-----KIREQEEKIREQEEKMWRQEEKIREQEEM--- 546
Query: 341 TKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGK 400
+E +++K+ EE ++ + ++ + E I+ ++ + E I++ + + K
Sbjct: 547 WREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEK 606
Query: 401 LKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEES 460
+ + +QE+ + E+EEK++++++++++ + + +E+++ + +E++ +K++E
Sbjct: 607 MWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ 666
Query: 461 KQLLKNNEKLITWLNKELNE-NQLVRKQD 488
++ + E+ I K++ E + +R+Q+
Sbjct: 667 EETMWRQEEKIREQEKKIREQEEKIREQE 695
Score = 67.4 bits (163), Expect = 4e-11
Identities = 51/297 (17%), Positives = 150/297 (50%), Gaps = 12/297 (4%)
Query: 161 KEEKLSLMQSLDDATKQLDFTRKTLAEKK---QELDKLRNEWASHTAALTNKHSQELTNE 217
+EEK+ + + + K+ + E+K QE + E K +++ +
Sbjct: 456 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQ 515
Query: 218 KEKALQAQVQYQQQHEQQ-KKDLEILHQQNIHQLQNRLSELEAA-----NKDLTERKYKG 271
+EK + + + ++Q E+ +++ +I Q+ + + + ++ E E ++ ++ ++
Sbjct: 516 EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQ 575
Query: 272 DSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEI 331
+ IRE + K+ EE+++ +++ + + + E+E+ + + + K+ E++I
Sbjct: 576 EEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKI 635
Query: 332 KDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQ 391
++++++ +E +E+ EE ++ + + + E I+ ++ + E I++ +
Sbjct: 636 REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQE 695
Query: 392 GDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQE 448
++ K+ + +QE+ + E+EEK++++++++ + Q +R+++QE K+QE
Sbjct: 696 EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWE--QEVRLRQQEE-KMQE 749
Score = 63.5 bits (153), Expect = 6e-10
Identities = 57/285 (20%), Positives = 146/285 (51%), Gaps = 23/285 (8%)
Query: 209 KHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERK 268
+ +E+ EKE+ ++ Q + + E++ ++LE + +H+ Q ++ E E ++ E K
Sbjct: 366 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE----EKMHE-QEKIREQEEKRQE--EEK 418
Query: 269 YKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEK----HVNQLQTKV 324
+ +E +AK+ EE+++ ++++ ++ + + HE+EK Q Q ++
Sbjct: 419 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEM 478
Query: 325 AVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKAN 384
E++I ++++ + R KE +E+ EE + + ++ + E I+ ++ +
Sbjct: 479 WRQEEKIHEQEE-IWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQE 537
Query: 385 EIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVC 444
E I++ + ++ + +QEK+ +EEK Q+++ ++ + +R +E++V
Sbjct: 538 EKIREQE--------EMWREEEKMHEQEKIW--EEEKRQEQEDKMWRQEEKIREQEEKVW 587
Query: 445 KLQEQL-EATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQD 488
+ +E++ E K+ E+ +++ K EK+ K + + +R+Q+
Sbjct: 588 RQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQE 632
Score = 62.0 bits (149), Expect = 2e-09
Identities = 62/345 (17%), Positives = 158/345 (45%), Gaps = 42/345 (12%)
Query: 157 LKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALT------NKH 210
L C K E + A KQL+ + L + + K E +A+ +++
Sbjct: 135 LTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRY 194
Query: 211 SQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYK 270
+ELT E++ AL ++ +++ K+ Q+ + +++ SE++ K+L + +
Sbjct: 195 IEELTKERD-ALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 253
Query: 271 GDSTI--RELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLE 328
+ ++L+A+ + +ELQ ++ + EN + ++E+ + + + K+ E
Sbjct: 254 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 313
Query: 329 QEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIK 388
++I+++++ + +E + I+EQ EE + + + + E ++ + + E ++
Sbjct: 314 EKIQEQEEKI---REQEEKIREQ----EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366
Query: 389 KLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLR-----IKEQEV 443
+ QE+++ EKEEK++++++ + + + +R + EQE
Sbjct: 367 R---------------------QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 405
Query: 444 CKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQD 488
+ QE+ +K+ E ++ + K+ K + + +R+Q+
Sbjct: 406 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 450
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 79.7 bits (195), Expect = 8e-15
Identities = 127/502 (25%), Positives = 216/502 (43%), Gaps = 88/502 (17%)
Query: 12 LQVKCKDCEERRVSIRMSIELQSVSNPVHRKDLVIRLTDDTDPFFLYNLVISEEDFQSLK 71
L+V+ ++ E R ++ I ++ + ++DL + V E + QSL
Sbjct: 486 LKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKF------------VAKENEVQSLH 533
Query: 72 FQQGLLVDFLAFPQKFIDLLQQCTQEHAKEIPRFLLQLVSPAAILDNSPAFLNVVETNPF 131
+ L D L Q+ L Q + K + + + IL+ + A ++
Sbjct: 534 SK---LTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHS 590
Query: 132 KHLTHLSLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDAT------KQLDFTRKTL 185
+ S +L E+ K +A K K+ + SL D T K + L
Sbjct: 591 QIAAQTSASVLAE---ELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLL 647
Query: 186 AEKKQELDKLRNEWASHTAALTN-KHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQ 244
+ Q+L L NE A+ L + S + ++K + L+ Q+Q++ ++ + + +IL+
Sbjct: 648 KAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKME--EFKILND 705
Query: 245 QN------IHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQR------T 292
QN + +LQ +SE NKD+ E+ K I+E KL VEE L+ T
Sbjct: 706 QNKALKSEVQKLQTLVSE--QPNKDVVEQMEK---CIQEKDEKLKTVEELLETGLIQVAT 760
Query: 293 KQEVLS-LRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQ 351
K+E L+ +R ENS+L E + + N Q A L +E+K
Sbjct: 761 KEEELNAIRTENSSLTKEVQDLKAKQND-QVSFASLVEELK------------------- 800
Query: 352 KVVLEENGEKNQVQLGKLEATIKSLSAELLK-ANE-------IIKKLQGDLKTLMGKLKL 403
KV+ E++G K+++ + L AELLK AN+ I K+Q L GK +
Sbjct: 801 KVIHEKDG--------KIKSVEELLEAELLKVANKEKTVQLSITSKVQELQNLLKGKEEQ 852
Query: 404 KNTVTIQQEKLLAEKEEKLQKEQKELQDV---GQSLRIKEQEVCKLQEQLEATVKKLEES 460
NT+ + +L EKE+ L K LQD+ +SL+ QEV + + ++ + EE
Sbjct: 853 MNTM----KAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEEL 908
Query: 461 KQLLKNNEKLITWLNKELNENQ 482
+ +LK E + L L E +
Sbjct: 909 EIVLKEKENELKRLEAMLKERE 930
Score = 63.2 bits (152), Expect = 8e-10
Identities = 117/522 (22%), Positives = 214/522 (40%), Gaps = 81/522 (15%)
Query: 31 ELQSVSNPVHRKDLVIRLTDDTDPFFLYNLVISEEDFQSLKFQQGLL------VDFLAFP 84
EL+ + V+ KD IRL ++ + N + E+F+ L Q L + L
Sbjct: 667 ELEKMQQSVYVKDDKIRLLEEQLQHEISNKM---EEFKILNDQNKALKSEVQKLQTLVSE 723
Query: 85 QKFIDLLQQ---CTQEHAKEIPRFLLQLVSPAAILDNSPAFLNVVETNPFKHLTHLS-LK 140
Q D+++Q C QE +++ L + + LN + T + LK
Sbjct: 724 QPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLK 783
Query: 141 LLPGNDVEIKKFLAGCLKC--SKEEKLSLMQSLDDA----------TKQLDFTRKTLAEK 188
+ V + K K+ K+ ++ L +A T QL T K ++
Sbjct: 784 AKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQLSITSKV--QE 841
Query: 189 KQELDKLRNEWASHTAALTNKHSQELTN---------EKEKALQAQVQYQQQHE------ 233
Q L K + E + A+ + ++L N E+ ++L+A VQ QH
Sbjct: 842 LQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASS 901
Query: 234 -QQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRT 292
Q ++LEI+ ++ ++L+ + L+ DL+ + E K S +E+ Q+
Sbjct: 902 ASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQN 961
Query: 293 KQEVLSLRRENSTLDVECHEKEKHV----NQLQTKVAVLEQEIKDKDQLVLRTKEAFDTI 348
Q+ S L V E+EK + N+L + +E + K + L + EA + +
Sbjct: 962 YQQASSFPPHEELLKV-ISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEAL 1020
Query: 349 QEQKVVLEENGEKN------QVQLGKLEA--TIKSLSAELL----------------KAN 384
+ +L++ K QV+ +LEA +K L ++ KA
Sbjct: 1021 ASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAK 1080
Query: 385 EIIKKLQG--DLKTLMGKLK----LKNTVTIQQEK---LLAEKEEKLQKEQKELQDVGQS 435
E + G ++K L KLK + + ++ EK +LAE E LQK Q+ ++
Sbjct: 1081 ECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENK 1140
Query: 436 LRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKE 477
++K E K +Q++++ E+ + L++ K I L +E
Sbjct: 1141 WKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRRE 1182
Score = 59.7 bits (143), Expect = 8e-09
Identities = 81/369 (21%), Positives = 161/369 (43%), Gaps = 57/369 (15%)
Query: 127 ETNPFKHLTHLSLKLLPGNDV---EIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFTRK 183
E N F++ H+S + + ++++ + + K+E L ++ + T QL+
Sbjct: 386 EHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLE---- 441
Query: 184 TLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILH 243
+++ EL+KLR ++A LT K + QQ E QKK+ E
Sbjct: 442 --SKQSAELNKLRQDYARLVNELTEKTGK----------------LQQEEVQKKNAEQAA 483
Query: 244 QQNIHQLQ--------------NRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEEL 289
Q QLQ R +E EAA +DL + ++ ++ L +KL+
Sbjct: 484 TQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSK 543
Query: 290 QRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKD-KDQLVLRTKEAFDTI 348
Q+ +Q ++ L + + V + + L+ +I+ Q+ +T +
Sbjct: 544 QQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAE 603
Query: 349 QEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVT 408
+ KV+ E++ Q+ + E ++ S L E +K D++ + LK +
Sbjct: 604 ELHKVIAEKD-----KQIKQTEDSLASERDRLTSKEEELK----DIQNMNFLLKAE---- 650
Query: 409 IQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATV-KKLEESKQLLKNN 467
+Q+ + LA ++ E +++Q QS+ +K+ ++ L+EQL+ + K+EE K L N
Sbjct: 651 VQKLQALANEQAAAAHELEKMQ---QSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQN 707
Query: 468 EKLITWLNK 476
+ L + + K
Sbjct: 708 KALKSEVQK 716
Score = 49.7 bits (117), Expect = 9e-06
Identities = 78/335 (23%), Positives = 145/335 (43%), Gaps = 31/335 (9%)
Query: 174 ATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHS--QELTNEKEKALQAQVQYQQQ 231
+ Q + L EK+ EL +L + L++K Q++ +E K ++Q++ +Q
Sbjct: 901 SASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDEN-KLFKSQIEQLKQ 959
Query: 232 HEQQKKDLEILHQQNIHQLQNRLSELEA------ANKDLTERKYKGDSTIRELKAK---- 281
Q+ H++ + + R E+ + KD E + K ++ +RE +
Sbjct: 960 QNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEA 1019
Query: 282 LSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRT 341
L+ E+ LQ K S R+ VE KE + +L KV+V + + L
Sbjct: 1020 LASTEKMLQ-DKVNKTSKERQQQVEAVELEAKEV-LKKLFPKVSV-PSNLSYGEWLHGFE 1076
Query: 342 KEAFDTI-----QEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKT 396
K+A + + E+ VLE ++ L+ + + L + I++KLQ ++
Sbjct: 1077 KKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQ 1136
Query: 397 LMGKLKLK-----NTVTIQQEKLLAEKE--EKLQKEQKELQDVGQSLRIKEQEVCKLQEQ 449
K K+K T+ Q + ++ E+L+ E K+++++ + E E+ K + +
Sbjct: 1137 EENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHLEMELEKAEME 1196
Query: 450 LEATVKKLEESKQLLKNNEKLITWLNKELNENQLV 484
V ++ E K L NE L T L E NE Q V
Sbjct: 1197 RSTYVTEVRELKAQL--NETL-TKLRTEQNERQKV 1228
Score = 47.0 bits (110), Expect = 6e-05
Identities = 47/239 (19%), Positives = 97/239 (40%), Gaps = 17/239 (7%)
Query: 247 IHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTL 306
IHQLQ + L A +D K + +E+ + + R K + +L +E++
Sbjct: 331 IHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVF 390
Query: 307 DVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQL 366
+ H + Q+Q K + ++++ E + +ENG
Sbjct: 391 QNKIHVSYQETQQMQMKFQQVREQME----------------AEIAHLKQENGILRDAVS 434
Query: 367 GKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQ 426
SAEL K + +L +L GKL+ + E+ + + +LQ+ +
Sbjct: 435 NTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAE 494
Query: 427 KELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVR 485
+ ++V +R + E Q+ L++ E Q L +++ T ++K+ E +L++
Sbjct: 495 RRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSL-HSKLTDTLVSKQQLEQRLMQ 552
Score = 38.1 bits (87), Expect = 0.026
Identities = 33/190 (17%), Positives = 82/190 (43%), Gaps = 19/190 (10%)
Query: 161 KEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEK 220
++E+ +D++ K + + + +QEL++LR+E NK + L E+E
Sbjct: 1135 EQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSE---------NKDIENLRREREH 1185
Query: 221 ALQAQVQYQQQHEQQKKDLE-ILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELK 279
+ E +K ++E + + +L+ +L+E + + K + + +
Sbjct: 1186 L---------EMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQ 1236
Query: 280 AKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVL 339
L ++ ++ + + + + + + E EKE L V L+Q ++ +Q +
Sbjct: 1237 QSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAVNQQLT 1296
Query: 340 RTKEAFDTIQ 349
+ KE + ++
Sbjct: 1297 KEKEHYQVLE 1306
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 79.7 bits (195), Expect = 8e-15
Identities = 66/312 (21%), Positives = 156/312 (50%), Gaps = 21/312 (6%)
Query: 194 KLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILH------QQNI 247
K+ N T HS E +E++ + Q Q +++ E Q + IL Q +
Sbjct: 150 KINNGTNPETTTSGGCHSPE--DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMAL 207
Query: 248 HQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLD 307
+ Q+ + +LE +DL R + EL+ LS V + ++ + + L +E L
Sbjct: 208 YYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALS 267
Query: 308 VECHEKEKHVNQLQTKVAVLEQEIK----DKDQLVLRTKEAFDTIQEQKVVLEENGEKNQ 363
+E + +L+ K A L+++++ +K ++ L KE ++ K++L + ++ Q
Sbjct: 268 LELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ--QQLQ 325
Query: 364 VQLGKLEATIKSLSAEL---LKANEIIKKLQGDLKTLMGKLKLK----NTVTIQQEKLLA 416
+ L ++S+SA+L ++ NE+ +L + M + + K +QE+ +
Sbjct: 326 AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR 385
Query: 417 EKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNK 476
E+EEK+++++++++ + + KE+++ + +E + +K+ ++++ E+ I L +
Sbjct: 386 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 445
Query: 477 ELNENQLVRKQD 488
+++E + +R+Q+
Sbjct: 446 KMHEQEKIREQE 457
Score = 79.7 bits (195), Expect = 8e-15
Identities = 65/308 (21%), Positives = 163/308 (52%), Gaps = 25/308 (8%)
Query: 161 KEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEK 220
KEEK+ + L++ + + R+ EK+QE +K+R + + ++ ++EK
Sbjct: 436 KEEKI---RELEEKMHEQEKIREQ-EEKRQEEEKIREQ------EKRQEQEAKMWRQEEK 485
Query: 221 ALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKA 280
+ + + ++Q E+ + E +H+Q + + + E E + E K + I K
Sbjct: 486 IREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ--EEKIREQEEIWRQKE 543
Query: 281 KLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLR 340
K+ EE+++ KQE R+E + H++E+ + + + KV E++I+++++ +
Sbjct: 544 KIHEQEEKIR--KQEEKMWRQEE-----KMHDQEEKIREQEEKVWRQEEKIREQEEKI-- 594
Query: 341 TKEAFDTIQEQKVVLEENGEKNQVQLGKL---EATIKSLSAELLKANEIIKKLQGDLKTL 397
+E + I+EQ+ + +E EK Q K+ E ++ ++ + E I++ + ++
Sbjct: 595 -REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQ 653
Query: 398 MGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKL 457
K++ + + +QE+ + E+EEK+ ++++++Q+ + +R +E+++ + + +L +K+
Sbjct: 654 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 713
Query: 458 EESKQLLK 465
+E ++ L+
Sbjct: 714 QEHQEHLE 721
Score = 65.9 bits (159), Expect = 1e-10
Identities = 63/362 (17%), Positives = 170/362 (46%), Gaps = 31/362 (8%)
Query: 157 LKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALT------NKH 210
L C K E + A KQL+ + L + + K E +A+ +++
Sbjct: 196 LTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRY 255
Query: 211 SQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYK 270
+ELT E++ AL ++ +++ K+ Q+ + +++ SE++ K+L + +
Sbjct: 256 IEELTKERD-ALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 314
Query: 271 GDSTI--RELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLE 328
+ ++L+A+ + +ELQ ++ + EN + ++E+ + + + K+ E
Sbjct: 315 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 374
Query: 329 QEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIK 388
++I+++++ + +E +E+ EE + + ++ + E + ++ + E++
Sbjct: 375 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 434
Query: 389 KLQGDLKTLMGKLKLKNTVTIQQEK-----------LLAEKEEKLQKEQKELQDVGQSLR 437
+ + ++ L K+ + + Q+EK E+E K+ ++++++++ + +R
Sbjct: 435 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 494
Query: 438 IKEQEVCKLQEQLEATVK-----KLEESKQLLKNNEKL----ITWLNKEL--NENQLVRK 486
+E+++ + +E++ K K +E +++ + EK+ W KE + + +RK
Sbjct: 495 EQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRK 554
Query: 487 QD 488
Q+
Sbjct: 555 QE 556
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 79.0 bits (193), Expect = 1e-14
Identities = 66/312 (21%), Positives = 156/312 (50%), Gaps = 21/312 (6%)
Query: 194 KLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILH------QQNI 247
K+ N T HS E +E++ + Q Q +++ E Q + IL Q +
Sbjct: 89 KINNGTNPETTTSGGCHSPE--DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMAL 146
Query: 248 HQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLD 307
+ Q+ + +LE +DL R + EL+ LS V + ++ + + L +E L
Sbjct: 147 YYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALS 206
Query: 308 VECHEKEKHVNQLQTKVAVLEQEIK----DKDQLVLRTKEAFDTIQEQKVVLEENGEKNQ 363
+E + +L+ K A L+++++ +K ++ L KE ++ K++L + ++ Q
Sbjct: 207 LELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ--QQLQ 264
Query: 364 VQLGKLEATIKSLSAEL---LKANEIIKKLQGDLKTLMGKLKLK----NTVTIQQEKLLA 416
+ L ++S+SA+L ++ NE+ +L + M + + K +QE+ +
Sbjct: 265 AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR 324
Query: 417 EKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNK 476
E+EEK+++++++++ + + KE+++ + +E + +K+ ++++ E+ I L +
Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEE 384
Query: 477 ELNENQLVRKQD 488
+++E + +R+Q+
Sbjct: 385 KMHEQEKIREQE 396
Score = 76.6 bits (187), Expect = 7e-14
Identities = 54/280 (19%), Positives = 148/280 (52%), Gaps = 14/280 (5%)
Query: 212 QELTNEKEKALQAQVQYQQQHEQQKKDLEIL--HQQNIHQLQNRLSELEAANKDLTERKY 269
+++ ++EK + + + ++Q E+ ++ E++ ++ + + + + E E + L E +
Sbjct: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMW 373
Query: 270 KGDSTIRELKAKLSGVEE--ELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVL 327
+ + IREL+ K+ E+ E + +QE +R + E+E + + + K+
Sbjct: 374 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR-----QEQEAKMWRQEEKIREQ 428
Query: 328 EQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEII 387
E++I+++++ + R +E I EQ+ + EE + Q ++ + E I+ E+ + E +
Sbjct: 429 EEKIREQEKKMWRQEEK---IHEQEKIREEEKRQEQEEMWRQEEKIRE-QEEIWRQKEKM 484
Query: 388 KKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQ 447
+ Q ++ K+ + QE+ + E+EEK+ ++++++++ + +R +E+++ + +
Sbjct: 485 HE-QEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQE 543
Query: 448 EQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQ 487
E ++ +K+ E ++ ++ EK+ K + + +R+Q
Sbjct: 544 EMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQ 583
Score = 75.5 bits (184), Expect = 1e-13
Identities = 66/337 (19%), Positives = 171/337 (50%), Gaps = 51/337 (15%)
Query: 161 KEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEK 220
KEEK M+ L++ + + + L EK E +K+R + + +E E+EK
Sbjct: 361 KEEK---MRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEK-------RQEEEKIREQEK 410
Query: 221 ALQAQVQYQQQHEQQKKDLEILHQQN---------IHQLQNRLSELEAANKDLTERKYKG 271
+ + + +Q E+ ++ E + +Q IH+ Q ++ E E + E ++
Sbjct: 411 RQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHE-QEKIREEEKRQEQ--EEMWRQ 467
Query: 272 DSTIRELKAKLSGVEEELQRTKQ---EVLSLRRENSTL---DVECHEKEKHVNQLQTKVA 325
+ IRE +EE+ R K+ E +R++ + + + H++E+ + + + K+
Sbjct: 468 EEKIRE--------QEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMW 519
Query: 326 VLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANE 385
E++I+++++ + +E + I+EQ+ +++E EK +G+ E E ++ E
Sbjct: 520 RQEEKIREQEEKI---REQEEKIREQEEMMQEQEEK----MGEQE--------EKMQEQE 564
Query: 386 IIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCK 445
+++ + ++ K++ + +QE+ + E+EEK++++++ +Q+ + + +E+++C+
Sbjct: 565 KMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCE 624
Query: 446 LQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQ 482
+E+++ +K+ ++ + E + +++ E+Q
Sbjct: 625 QEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ 661
Score = 71.2 bits (173), Expect = 3e-12
Identities = 61/297 (20%), Positives = 147/297 (49%), Gaps = 26/297 (8%)
Query: 161 KEEKLSLMQSLDDATKQLDFTRKTLAEK---KQELDKLRNEWASHTAALTNKHSQELTNE 217
+EEK + + + K+ + K ++ +++ +K+R + H QE E
Sbjct: 395 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE 454
Query: 218 KEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRE 277
+EK Q+Q E +++ +I Q+ I + + ++ E E K E+ ++ + + +
Sbjct: 455 EEKR-------QEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ-EEKVWRQEEKMHD 506
Query: 278 LKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQL 337
+ K+ EE++ R ++++ + + + E+E+ + + + K+ EQE K ++Q
Sbjct: 507 QEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMG--EQEEKMQEQE 564
Query: 338 VLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTL 397
+R +E + I+EQ+ + E EK I+ ++ + E I++ + ++
Sbjct: 565 KMRRQE--EKIREQEEKIREQKEK-----------IREQEEKIWEQEEKIREQEEMMQEQ 611
Query: 398 MGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATV 454
K+ + +QE+ + E+EEK++++++++ + LR +E+++ + QE LEA +
Sbjct: 612 EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668
Score = 70.1 bits (170), Expect = 6e-12
Identities = 67/361 (18%), Positives = 178/361 (49%), Gaps = 30/361 (8%)
Query: 157 LKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALT------NKH 210
L C K E + A KQL+ + L + + K E +A+ +++
Sbjct: 135 LTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRY 194
Query: 211 SQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYK 270
+ELT E++ AL ++ +++ K+ Q+ + +++ SE++ K+L + +
Sbjct: 195 IEELTKERD-ALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 253
Query: 271 GDSTI--RELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLE 328
+ ++L+A+ + +ELQ ++ + EN + ++E+ + + + K+ E
Sbjct: 254 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 313
Query: 329 QEIKDKDQLVL----RTKEAFDTIQEQKVVLEENGEKNQVQ---LGKLEATIKSLSAELL 381
++I+++++ + + +E + ++ Q+ ++ E EK + Q + + E ++ L +
Sbjct: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMW 373
Query: 382 KANEIIKKLQGDL----KTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLR 437
+ E I++L+ + K + K + I++++ E+E K+ ++++++++ + +R
Sbjct: 374 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 433
Query: 438 IKEQEVCKLQEQLEATVK-----KLEESKQLLKNNEKL----ITWLNKE-LNENQLVRKQ 487
+E+++ + +E++ K K +E +++ + EK+ W KE ++E + +RKQ
Sbjct: 434 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493
Query: 488 D 488
+
Sbjct: 494 E 494
Score = 67.8 bits (164), Expect = 3e-11
Identities = 63/311 (20%), Positives = 155/311 (49%), Gaps = 28/311 (9%)
Query: 187 EKKQELDKLRNEWASHTAALTNK-HSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQ 245
EK + L+++ E L K H QE E+E+ Q + + ++Q ++Q+++ ++ Q+
Sbjct: 363 EKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 422
Query: 246 NIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENST 305
++ E E ++ ++ ++ + I E + + EE +R +QE + + E
Sbjct: 423 E------KIREQEEKIREQEKKMWRQEEKIHEQEK----IREEEKRQEQEEMWRQEEKIR 472
Query: 306 LDVEC-------HEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEEN 358
E HE+EK + + + KV E+++ D+++ + +E + + Q+ + E
Sbjct: 473 EQEEIWRQKEKMHEQEK-IRKQEEKVWRQEEKMHDQEEKI---REQEEKMWRQEEKIREQ 528
Query: 359 GEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEK 418
EK + Q K+ + + + K E +K+Q K + K++ +QE+ + E+
Sbjct: 529 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIR-----EQEEKIREQ 583
Query: 419 EEKLQKEQKELQDVGQSLRIKEQEVCKLQEQL-EATVKKLEESKQLLKNNEKLITWLNKE 477
+EK++++++++ + + +R +E+ + + +E++ E K E+ +++ + EK+ K
Sbjct: 584 KEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 643
Query: 478 LNENQLVRKQD 488
+ +R+Q+
Sbjct: 644 WEQEVRLRQQE 654
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 79.0 bits (193), Expect = 1e-14
Identities = 82/382 (21%), Positives = 156/382 (40%), Gaps = 56/382 (14%)
Query: 157 LKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTN 216
L+ K E +L + + D T+QL + KT+ E ++ +L E +AL + L +
Sbjct: 1495 LETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEAS-LEH 1553
Query: 217 EKEKALQAQVQYQQ----------QHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTE 266
E+ K L+AQ+++ Q + +++ + + H + + LQ L + +
Sbjct: 1554 EEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALR 1613
Query: 267 RKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLR-------------------------- 300
K K + + E++ +LS +++V SL+
Sbjct: 1614 VKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAI 1673
Query: 301 --RENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEEN 358
R N+ L E E V Q + + EQE+ + T E + Q L
Sbjct: 1674 VERRNNLLQAELEELRAVVEQTERSRKLAEQEL-------IETSERVQLLHSQNTSLINQ 1726
Query: 359 GEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEK 418
+K L +L+ ++ E A E KK D + +LK + + E++
Sbjct: 1727 KKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNM 1786
Query: 419 EEKLQKEQKELQDVGQ--------SLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKL 470
E+ ++ Q L + Q L+ E V +L+ +LEA K+ ES + ++ +E+
Sbjct: 1787 EQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERR 1846
Query: 471 ITWLNKELNENQ--LVRKQDVL 490
I L + E++ L+R QD++
Sbjct: 1847 IKELTYQTEEDRKNLLRLQDLV 1868
Score = 73.2 bits (178), Expect = 7e-13
Identities = 70/357 (19%), Positives = 161/357 (45%), Gaps = 44/357 (12%)
Query: 161 KEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQEL-TNEKE 219
+E+ +SL+Q +D Q+ + LA+ ++ D+L + NK E E
Sbjct: 874 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQL----------IKNKIQLEAKVKEMN 923
Query: 220 KALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELK 279
+ L+ + + + +K+ LE +L+ + +LE + + K+ ++ ++ L
Sbjct: 924 ERLEDEEEMNAELTAKKRKLE----DECSELKRDIDDLELTLAKVEKEKHATENKVKNLT 979
Query: 280 AKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVL 339
+++G++E + + +E +L+ + + +E VN L LEQ++ D + +
Sbjct: 980 EEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLE 1039
Query: 340 R---------------------TKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSA 378
+ T+E+ ++ K L+E +K +L L A I+ A
Sbjct: 1040 QEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQA 1099
Query: 379 ELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRI 438
+ + +K+LQ ++ L +L+ + T + EKL ++ +L++ + L++ G + +
Sbjct: 1100 LGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSV 1159
Query: 439 -------KEQEVCKLQEQL-EATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQ 487
+E E K++ L EAT++ + L K + + L ++++ Q V+++
Sbjct: 1160 QIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQK 1216
Score = 71.6 bits (174), Expect = 2e-12
Identities = 78/343 (22%), Positives = 161/343 (46%), Gaps = 36/343 (10%)
Query: 173 DATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQH 232
D+ +L L KQ+L+K ++E+ +T+ Q + + + Q +
Sbjct: 1198 DSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMN 1257
Query: 233 EQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIREL-KAKLSGVE--EEL 289
E + K E Q++++ L ++ ++L+ N +L+ + + ++ I +L + KL+ + E+L
Sbjct: 1258 EHRSKAEET--QRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDL 1315
Query: 290 QRTKQEVL-----------SLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLV 338
+R +E + S R + L + E+ + +LQ ++ E+
Sbjct: 1316 KRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQ----- 1370
Query: 339 LRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLM 398
RTK D IQ + LEE +K +L + E +++++A+ + +LQ +++ LM
Sbjct: 1371 WRTKYETDAIQRTEE-LEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLM 1429
Query: 399 GKLKLKNTVTIQQEK-------LLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLE 451
++ N +K +LAE ++K ++ Q EL+ + R E+ KL+ E
Sbjct: 1430 VDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYE 1489
Query: 452 ATVKKLEESKQLLKNNEKLITWLNKEL-------NENQLVRKQ 487
+++ LE K+ KN ++ I+ L ++L +E + VRKQ
Sbjct: 1490 ESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQ 1532
Score = 66.2 bits (160), Expect = 9e-11
Identities = 79/391 (20%), Positives = 168/391 (42%), Gaps = 71/391 (18%)
Query: 164 KLSLMQSLDDATKQLDFTRKTLAEK---KQELDKLRNEWASHTAALTNKHSQELTNEKEK 220
K +L +L A D R+ E+ K EL ++ ++ S A K+ + E+
Sbjct: 1326 KNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEE 1385
Query: 221 ALQAQVQYQQQHEQQKKDLEILH------QQNIHQLQNRLSEL-------EAANKDLTER 267
+A+ + Q+ ++ ++ +E ++ ++ H+LQN + +L AA L ++
Sbjct: 1386 LEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKK 1445
Query: 268 KYKGDSTIRELKAKLSGVEEELQRTKQEVLSL---------------------RRENSTL 306
+ D + E K K + EL+ +++E SL +REN L
Sbjct: 1446 QRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNL 1505
Query: 307 DVEC--------------HEKEKHVNQLQTKVAVLEQEIKD-------KDQLVLRTKEAF 345
E HE EK QL+ + L+ +++ ++ +LR + F
Sbjct: 1506 QEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEF 1565
Query: 346 DTIQEQ--KVVLEENGEKNQVQLGKL---EATIKSLSAELLKANEII---KKLQGDLKTL 397
+ I+ + + + E++ E Q + L ++ SL AE NE + KK++GDL +
Sbjct: 1566 NQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEM 1625
Query: 398 MGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKL 457
+L N + + +K + + L+ Q +L D ++ ++ + ++ + +L
Sbjct: 1626 EIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAEL 1685
Query: 458 EESKQLLKNNEKLITWLNKELNENQLVRKQD 488
EE + +++ E+ +++L E +L+ +
Sbjct: 1686 EELRAVVEQTER-----SRKLAEQELIETSE 1711
Score = 58.2 bits (139), Expect = 2e-08
Identities = 67/304 (22%), Positives = 133/304 (43%), Gaps = 45/304 (14%)
Query: 186 AEKKQELDKLRNEWASHTAALTNKHSQ--ELTNEKEKALQAQVQYQQQHEQQKKDLEILH 243
AE+++E+ ++ E+ AL ++ EL + LQ + Q Q + ++ +L
Sbjct: 843 AEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 902
Query: 244 QQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRREN 303
++ ++N++ +LEA K++ ER + EL AK +E+E K+++ L
Sbjct: 903 ERCDQLIKNKI-QLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE--- 958
Query: 304 STLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQ 363
L + EKEKH + KV L +E+ D+++ + + ++K L+E ++
Sbjct: 959 --LTLAKVEKEKHATE--NKVKNLTEEMAGLDEIIAK-------LTKEKKALQEAHQQ-- 1005
Query: 364 VQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQ 423
+ L AE K N + K K+KL+ V + E L+
Sbjct: 1006 --------ALDDLQAEEDKVNTLTK----------AKVKLEQQVD--------DLEGSLE 1039
Query: 424 KEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQL 483
+E+K D+ ++ R E ++ QE + ++ + LK + + LN + + Q
Sbjct: 1040 QEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQA 1099
Query: 484 VRKQ 487
+ Q
Sbjct: 1100 LGSQ 1103
Score = 52.8 bits (125), Expect = 1e-06
Identities = 80/362 (22%), Positives = 154/362 (42%), Gaps = 25/362 (6%)
Query: 123 LNVVETNPFKHLTHLSLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFTR 182
L + + KH T +K L + + +A K K + + Q+LDD + D
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN 1018
Query: 183 KTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEIL 242
TL + K +L++ ++ + K +L K K L+ ++ Q+ DLE
Sbjct: 1019 -TLTKAKVKLEQQVDDLEG-SLEQEKKVRMDLERAKRK-LEGDLKLTQESIM---DLEND 1072
Query: 243 HQQNIHQLQNRLSELEAANKDLTERKYKGDST---IRELKAKLSGVEEELQRTKQEVLSL 299
QQ +L+ + EL A N + + + G ++EL+A++ +EEEL+ + +
Sbjct: 1073 KQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKV 1132
Query: 300 RRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENG 359
+ S L E E + + + +V Q+ + K + Q+ + LEE
Sbjct: 1133 EKLRSDLSRELEEISERLEEAGGATSV---------QIEMNKKREAE-FQKMRRDLEEAT 1182
Query: 360 EKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLK-NTVTIQQEKLLAEK 418
+++ L AEL + + +++++ L+ + KL+ + VT E+++ K
Sbjct: 1183 LQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAK 1242
Query: 419 EEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLE----ESKQLLKNNEKLITWL 474
L+K + L+D R K +E + L + KL+ E + L E LI+ L
Sbjct: 1243 AN-LEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQL 1301
Query: 475 NK 476
+
Sbjct: 1302 TR 1303
Score = 52.8 bits (125), Expect = 1e-06
Identities = 63/325 (19%), Positives = 138/325 (42%), Gaps = 42/325 (12%)
Query: 164 KLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTN--------KHSQELT 215
K + L++ QL + AE ++++ L++ L + K + +
Sbjct: 1615 KKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIV 1674
Query: 216 NEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTI 275
+ LQA+++ + +Q + L +Q + + R+ L + N L +K K D+ +
Sbjct: 1675 ERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADL 1734
Query: 276 RELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKD 335
+L+ ++ +E + +++ + + + E +++ L+ +EQ IKD
Sbjct: 1735 SQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQ 1794
Query: 336 QLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLK 395
+ E + + + G+K QL KLEA ++ L NE+ + + + +
Sbjct: 1795 H----------RLDEAEQIALKGGKK---QLQKLEARVRELE------NELEAEQKRNAE 1835
Query: 396 TLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVK 455
++ G K + + K L + E+ +K LQD+ V KLQ +++A +
Sbjct: 1836 SVKGMRKSERRI-----KELTYQTEEDRKNLLRLQDL----------VDKLQLKVKAYKR 1880
Query: 456 KLEESKQLLKNNEKLITWLNKELNE 480
+ EE+++ N + EL+E
Sbjct: 1881 QAEEAEEQANTNLSKFRKVQHELDE 1905
Score = 52.4 bits (124), Expect = 1e-06
Identities = 67/318 (21%), Positives = 137/318 (43%), Gaps = 25/318 (7%)
Query: 147 VEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKL--RNEWASHTA 204
+ +KK + G L + + + +A KQ+ + L + + +LD N+
Sbjct: 1612 LRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENI 1671
Query: 205 ALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDL 264
A+ + + L E E+ L+A V+ Q E+ +K L +Q + + R+ L + N L
Sbjct: 1672 AIVERRNNLLQAELEE-LRAVVE---QTERSRK----LAEQELIETSERVQLLHSQNTSL 1723
Query: 265 TERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKV 324
+K K D+ + +L+ ++ +E + +++ + + + E +++ L+
Sbjct: 1724 INQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMK 1783
Query: 325 AVLEQEIKD-------KDQLVLRT-KEAFDTIQEQKVVLEENGEKNQVQ-------LGKL 369
+EQ IKD +Q+ L+ K+ ++ + LE E Q + + K
Sbjct: 1784 KNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKS 1843
Query: 370 EATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKEL 429
E IK L+ + + + + +LQ + L K+K + E+ K +K Q EL
Sbjct: 1844 ERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHEL 1903
Query: 430 QDVGQSLRIKEQEVCKLQ 447
+ + I E +V KL+
Sbjct: 1904 DEAEERADIAESQVNKLR 1921
Score = 45.1 bits (105), Expect = 2e-04
Identities = 43/171 (25%), Positives = 84/171 (49%), Gaps = 12/171 (7%)
Query: 323 KVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEEN-----GEKNQVQLGKLEATIKSLS 377
K A E+E+ + R KEA + + ++ LEE EKN +QL +++A +L+
Sbjct: 841 KSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQL-QVQAEQDNLA 899
Query: 378 AELLKANEIIK-KLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSL 436
+ +++IK K+Q L K+K N +E++ AE K +K + E ++ + +
Sbjct: 900 DAEERCDQLIKNKIQ-----LEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDI 954
Query: 437 RIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQ 487
E + K++++ AT K++ + + +++I L KE Q +Q
Sbjct: 955 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1005
Score = 33.9 bits (76), Expect = 0.49
Identities = 47/227 (20%), Positives = 97/227 (42%), Gaps = 22/227 (9%)
Query: 263 DLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQT 322
D+ +YK T KA L G+ EE++ + + R + + V + K + + +
Sbjct: 750 DIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLARMEYKKLLERRD 809
Query: 323 KVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLK 382
+ V++ I+ AF ++ + K ++ + E + S+ E +
Sbjct: 810 SLLVIQWNIR-----------AFMGVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFTR 858
Query: 383 ANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQE 442
E ++K + K L K+ V++ QEK + + ++Q EQ L D + +
Sbjct: 859 LKEALEKSEARRKELEEKM-----VSLLQEK--NDLQLQVQAEQDNLADAEERC----DQ 907
Query: 443 VCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQDV 489
+ K + QLEA VK++ E + + +T ++L + K+D+
Sbjct: 908 LIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDI 954
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 79.0 bits (193), Expect = 1e-14
Identities = 85/345 (24%), Positives = 160/345 (46%), Gaps = 42/345 (12%)
Query: 161 KEEKLSLMQSLDDATKQLDFTRKT---LAEKKQELDKLRNEWASHTAALTNKHSQELTNE 217
++ K L Q LDD T LD R+ L +K+++ D+L E S +A + +
Sbjct: 1419 EKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEA 1478
Query: 218 KEK-------------ALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDL 264
+EK AL+A+ ++++Q++Q + D+E L + + ELE + + L
Sbjct: 1479 REKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSK-DDVGKNVHELEKSKRAL 1537
Query: 265 TERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLR-----------RENSTLDVECHEK 313
++ + E++ +L +E+ELQ T+ L L R+ T D + EK
Sbjct: 1538 EQQ-------VEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEK 1590
Query: 314 EKH-VNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEE-NGEKNQV--QLGKL 369
++ + Q++ A LE E K + V K+ +++ + +E N +++V QL KL
Sbjct: 1591 KRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKL 1650
Query: 370 EATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKE---EKLQKEQ 426
+A +K EL +A ++ K KLK +Q ++ LA E ++E+
Sbjct: 1651 QAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQER 1710
Query: 427 KELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLI 471
EL D + + + + +LEA + +LEE + ++N +L+
Sbjct: 1711 DELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELL 1755
Score = 76.6 bits (187), Expect = 7e-14
Identities = 80/310 (25%), Positives = 145/310 (46%), Gaps = 41/310 (13%)
Query: 182 RKTLAEKKQELDKLRNEWASHTAALTNKHSQ--ELTNEKEKALQAQVQYQQQHEQQKKDL 239
RK A+K+Q+L L+ + A L +H Q + + + LQ +Q+ E Q KD
Sbjct: 803 RKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVT---RQEEELQAKDE 859
Query: 240 EILH-QQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLS 298
E+L ++ +++ L E+E ++ L E K + A+ E EL +E+ +
Sbjct: 860 ELLKVKEKQTKVEGELEEMERKHQQLLEEK--------NILAEQLQAETELFAEAEEMRA 911
Query: 299 -LRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEE 357
L + L+ H+ E V + + + +L+ E K + +E D EE
Sbjct: 912 RLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLD---------EE 962
Query: 358 NGEKNQVQLGKL--EATIKSLSAELLKANEIIKKLQGDLKTLMGKL------------KL 403
G + ++QL K+ EA IK + E+L + K + K + ++ K
Sbjct: 963 EGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKA 1022
Query: 404 KNTVTIQ--QEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESK 461
KN I+ QE ++++ EE+L+KE+K Q++ ++ R + E LQ+Q+ +++E K
Sbjct: 1023 KNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELK 1082
Query: 462 -QLLKNNEKL 470
QL K E+L
Sbjct: 1083 LQLAKKEEEL 1092
Score = 74.3 bits (181), Expect = 3e-13
Identities = 88/354 (24%), Positives = 159/354 (44%), Gaps = 52/354 (14%)
Query: 162 EEKLSLMQSLDDATK---QLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEK 218
EEK L + L T+ + + R LA KKQEL+++ ++ S + +Q L NEK
Sbjct: 887 EEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEE-EEERNQILQNEK 945
Query: 219 EKALQAQVQ------YQQQHEQQKKDLE-ILHQQNIHQLQNRLSELEAANKDLTERKYKG 271
+K +QA +Q +++ +QK LE + + I +++ + LE N + K
Sbjct: 946 KK-MQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLM 1004
Query: 272 DSTIRELKAKLSGVEEELQ-----RTKQEVL------SLRRENST----------LDVEC 310
+ I E ++L+ EE+ + R KQEV+ L++E T LD E
Sbjct: 1005 EDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGET 1064
Query: 311 HEKEKHVNQLQTKVAVLEQEIKDK-----------DQLVLRTKEAFDTIQE---QKVVLE 356
+ + + +LQ ++ L+ ++ K D L A ++E Q L+
Sbjct: 1065 TDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQ 1124
Query: 357 ENGEKNQVQLGKLEATIKSLSAELLKANEIIK-KLQGDLKTLMGKLKLKNTVTIQQEKLL 415
E+ E + K E + LS EL E +K +L+ L T + +L+ + +L
Sbjct: 1125 EDFESEKASRNKAEKQKRDLSEEL----EALKTELEDTLDTTAAQQELRTKREQEVAELK 1180
Query: 416 AEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEK 469
EE+ + + ++QD+ Q +E+ + EQ + LE++KQ L+ + K
Sbjct: 1181 KALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNK 1234
Score = 66.2 bits (160), Expect = 9e-11
Identities = 70/346 (20%), Positives = 151/346 (43%), Gaps = 23/346 (6%)
Query: 157 LKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTN 216
++ EE +Q+ +DA +L+ + + + + + R+E L K +EL
Sbjct: 1544 MRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEA 1603
Query: 217 EKE---KALQAQVQYQQQHEQQKKDLEI-------LHQQNIHQLQNRLSELEAANKDLTE 266
E E K V +++ E KDLE + I QL+ ++++ ++L E
Sbjct: 1604 ELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEE 1663
Query: 267 RKYKGDSTI---RELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTK 323
+ D +E + KL +E E+ + ++E+ S R + E E + +
Sbjct: 1664 ARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASG 1723
Query: 324 VAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKA 383
+ L E + + + + +E + Q +L + K +Q+ L A + + + K+
Sbjct: 1724 KSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKS 1783
Query: 384 NEIIKKLQGDLKTLMGKL---------KLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQ 434
+ ++L+ K L KL K K T++ + K+ + EE+L++E KE +
Sbjct: 1784 DNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKI-GQLEEQLEQEAKERAAANK 1842
Query: 435 SLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNE 480
+R E+++ ++ Q+E + ++ K+ ++ + L ++L E
Sbjct: 1843 LVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEE 1888
Score = 63.5 bits (153), Expect = 6e-10
Identities = 85/366 (23%), Positives = 160/366 (43%), Gaps = 57/366 (15%)
Query: 161 KEEKLS-LMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTN--KHSQELTNE 217
KEE+L + DD T + K + E + ++ +L+ ++ S A+ K ++L+ E
Sbjct: 1088 KEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEE 1147
Query: 218 KEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSEL----EAANKDLTERKYKGDS 273
E AL+ +++ +++L +Q + +L+ L E EA +D+ +R
Sbjct: 1148 LE-ALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALE 1206
Query: 274 TIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECH-------EKEKHVNQLQTKVAV 326
+ E + + L++ KQ L +N L E E E +L +V
Sbjct: 1207 ELSEQLEQAKRFKANLEKNKQ---GLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQE 1263
Query: 327 LEQEIKDKDQLVLRTKEAFDTIQEQK---VVLEENGEKNQVQLGKLEATIKSLSAELLKA 383
L ++ + D+L + E +Q + L E EK ++ K A SL ++L
Sbjct: 1264 LHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAA---SLESQLQDT 1320
Query: 384 NEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEV 443
E++++ KL L + + + L E++ LQ++Q+E ++ ++L E++V
Sbjct: 1321 QELLQE------ETRQKLNLSSRI-----RQLEEEKNSLQEQQEEEEEARKNL---EKQV 1366
Query: 444 CKLQEQLEATVKKL-----------EESKQLLKN--------NEKLITWLNKELNENQLV 484
LQ QL T KK+ E K+LLK+ EK + + E +N+L
Sbjct: 1367 LALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQ 1426
Query: 485 RKQDVL 490
++ D L
Sbjct: 1427 QELDDL 1432
Score = 62.0 bits (149), Expect = 2e-09
Identities = 75/339 (22%), Positives = 142/339 (41%), Gaps = 21/339 (6%)
Query: 177 QLDFTRKTLAEKKQELDKLRNEWASHTAALTN---KHSQELTNEKE---KALQAQVQYQQ 230
Q+ + L K +EL K++ + L KH Q+L EK + LQA+ +
Sbjct: 846 QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKH-QQLLEEKNILAEQLQAETELFA 904
Query: 231 QHEQQKKDLEILHQQN---IHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEE 287
+ E+ + L Q+ +H L++R+ E E N+ L K K + I++L+ +L EE
Sbjct: 905 EAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLD--EE 962
Query: 288 ELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDT 347
E R K L+ E T + + + E+ + L+ + + +E K + +
Sbjct: 963 EGARQK-----LQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAE 1017
Query: 348 IQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTV 407
+E+ L + K +V + LE +K + + +KL G+ L ++
Sbjct: 1018 EEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQ 1077
Query: 408 TIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNN 467
+ + LA+KEE+LQ G + + K+ +L+A + +L+E + K +
Sbjct: 1078 IDELKLQLAKKEEELQGALAR----GDDETLHKNNALKVVRELQAQIAELQEDFESEKAS 1133
Query: 468 EKLITWLNKELNENQLVRKQDVLGPSTTPPAHSSSNTIR 506
++L+E K ++ T A T R
Sbjct: 1134 RNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKR 1172
Score = 61.6 bits (148), Expect = 2e-09
Identities = 86/367 (23%), Positives = 160/367 (43%), Gaps = 45/367 (12%)
Query: 157 LKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNK--HSQEL 214
L C + + + K+LD + L K E D+LR E A + L N+ + L
Sbjct: 1236 LACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTL 1295
Query: 215 TNEKEK----------ALQAQVQYQQQHEQQKKDLEILHQQNIHQ-------LQNRLSEL 257
E EK +L++Q+Q Q+ Q++ ++ I Q LQ + E
Sbjct: 1296 LEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEE 1355
Query: 258 EAANKDLTERKYKGDSTIRELKAKLS---GVEEELQRTKQ------EVLSLRRENSTLDV 308
E A K+L ++ S + + K K+ G E L+ K+ E LS R E L
Sbjct: 1356 EEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAY 1415
Query: 309 ECHEKEKHVNQLQTKVAVLEQEIKDKDQL---VLRTKEAFDTI--QEQKVVLEENGEKNQ 363
+ EK K N+LQ ++ L ++ + Q+ + + ++ FD + +E+ + E+++
Sbjct: 1416 DKLEKTK--NRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDR 1473
Query: 364 VQLGKLEATIKSLS-----AELLKANEII----KKLQGDLKTLMGKLKLKNTVTIQQEKL 414
+ E K+LS E L+A E K+L+ D++ LM + EK
Sbjct: 1474 AEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKS 1533
Query: 415 LAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLL-KNNEKLITW 473
E+++++ + +L+++ L+ E +L+ ++A + E Q + NE+
Sbjct: 1534 KRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRL 1593
Query: 474 LNKELNE 480
L K++ E
Sbjct: 1594 LIKQVRE 1600
Score = 60.1 bits (144), Expect = 6e-09
Identities = 66/345 (19%), Positives = 157/345 (45%), Gaps = 53/345 (15%)
Query: 167 LMQSLDDATKQLDFTRKTLAEKKQELDKLRNEW--------ASHTAALTNKHSQ------ 212
LM S DD K + K+ +Q+++++R + A+ A L + +
Sbjct: 1516 LMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQ 1575
Query: 213 ---------ELTNEKEKALQAQV---QYQQQHEQQKKDLEILHQQNIH-QLQNRLSELEA 259
E EK++ L QV + + + E++++ L + ++ + L++ +++EA
Sbjct: 1576 FERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEA 1635
Query: 260 ANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQ 319
ANK D I++L+ KL ++ QR +E + R E + + E EK +
Sbjct: 1636 ANK-------ARDEVIKQLR-KLQAQMKDYQRELEEARASRDE---IFAQSKESEKKLKS 1684
Query: 320 LQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQ-------KVVLEENGEKNQVQLGKLEAT 372
L+ ++ L++E+ ++ ++ D + ++ K L + + + ++ +LE
Sbjct: 1685 LEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEE 1744
Query: 373 IKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDV 432
++ + + N+ +K + TL +L + + + + + E + ++ + +LQ++
Sbjct: 1745 LEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQEL 1804
Query: 433 GQSLRIK--------EQEVCKLQEQLEATVKKLEESKQLLKNNEK 469
+++ K E ++ +L+EQLE K+ + +L++ EK
Sbjct: 1805 EGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEK 1849
Score = 59.3 bits (142), Expect = 1e-08
Identities = 75/359 (20%), Positives = 168/359 (46%), Gaps = 57/359 (15%)
Query: 160 SKEEKLSLMQSLDDATKQLDFTRKTLA-----EKKQELDKLRNEWASHTAALTNKHSQEL 214
++E+K L++ + + +L+ RK A +KK E+D L++ A AA NK E+
Sbjct: 1587 NEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEID-LKDLEAQIEAA--NKARDEV 1643
Query: 215 TNEKEKALQAQVQ-YQQQHEQQKKDLEILHQQN-------------IHQLQNRLSELEAA 260
+ K LQAQ++ YQ++ E+ + + + Q+ I QLQ L+ E A
Sbjct: 1644 IKQLRK-LQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERA 1702
Query: 261 NKDLTERKYK----------GDSTI----RELKAKLSGVEEELQ--RTKQEVLSLRRENS 304
+ + + + G S + R L+A+++ +EEEL+ ++ E+L+ R +
Sbjct: 1703 RRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKT 1762
Query: 305 TLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKN-- 362
TL V+ E L + + ++ + QL + KE +QE + ++ +
Sbjct: 1763 TLQVDTLNAE-----LAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATIS 1817
Query: 363 --QVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEK-E 419
+ ++G+LE ++ + E AN+++++ + LK + + ++ E+ A++ +
Sbjct: 1818 ALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIF--------MQVEDERRHADQYK 1869
Query: 420 EKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKEL 478
E+++K ++ + + L E+E + ++L+++ + + + ++ L L
Sbjct: 1870 EQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRL 1928
Score = 54.3 bits (129), Expect = 3e-07
Identities = 76/356 (21%), Positives = 151/356 (42%), Gaps = 40/356 (11%)
Query: 162 EEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHS---------- 211
+E+ +L +QL+ + +L E+++E ++ R AL ++ +
Sbjct: 1325 QEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDL 1384
Query: 212 ---QELTNEKEKALQAQVQYQQQHEQQKKDLEILH------QQNIHQLQNRLSELEAANK 262
+ L K+K L+ Q+ E++ + L QQ + L L
Sbjct: 1385 GTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVAS 1444
Query: 263 DLTERKYKGDSTIRELKAKLSGVEEELQRTKQEV-------LSLRRENSTLDVECHEKEK 315
+L +++ K D + E K+ + EE R + E LSL R L+ KE+
Sbjct: 1445 NLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLAR---ALEEALEAKEE 1501
Query: 316 HVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKS 375
Q + A +E + KD + E +++ K LE+ E+ + QL +LE +++
Sbjct: 1502 FERQNKQLRADMEDLMSSKDDVGKNVHE----LEKSKRALEQQVEEMRTQLEELEDELQA 1557
Query: 376 LSAELLKANEIIKKLQG----DLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQD 431
L+ ++ ++ DL+T + + K + I+Q + E E +L+ E+K+
Sbjct: 1558 TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVR---ELEAELEDERKQRAL 1614
Query: 432 VGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQ 487
S + E ++ L+ Q+EA K +E + L+ + + +EL E + R +
Sbjct: 1615 AVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDE 1670
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 79.0 bits (193), Expect = 1e-14
Identities = 77/358 (21%), Positives = 168/358 (46%), Gaps = 11/358 (3%)
Query: 132 KHLTHLSLKLLPGNDVEIKKFLAGCL-KCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQ 190
K LT L+++L + K+ L K EEK L+ + D + ++D K +
Sbjct: 1374 KQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALE 1433
Query: 191 ELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEI-LHQQNIHQ 249
++D N+++ ++ +Q KE +Q +++ ++ +E KD +I L ++ + Q
Sbjct: 1434 QVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYE---KDEQINLLKEELDQ 1490
Query: 250 LQNRLSELEAANKDLTERKYKGDSTIR-ELKAKLSGVEEELQRTKQEVLSLRRENSTLDV 308
R L+ +D + K +S + ELK++ + + E Q+ + + N L
Sbjct: 1491 QNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKN 1550
Query: 309 ECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGK 368
+K+ +L K+ ++ ++KD V +E T++ Q ++ E + +L
Sbjct: 1551 YNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEH 1610
Query: 369 LEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQK- 427
+ ++KS EL KA E + + K K K + + +++LL++ EEK ++ +K
Sbjct: 1611 VNLSVKSKEEEL-KALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKG 1669
Query: 428 ---ELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQ 482
L ++ L+ +E+EV L+E+L++ E+ + ++ + + + +E ++Q
Sbjct: 1670 TESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQ 1727
Score = 76.6 bits (187), Expect = 7e-14
Identities = 80/326 (24%), Positives = 155/326 (47%), Gaps = 32/326 (9%)
Query: 181 TRKTLAEKKQELDKLRNEWASHTAALTNKHSQEL------TNEKEKALQAQVQYQQQHEQ 234
T + L K+ EL+ L +E S +K +EL T++ ++ L+A++ Q+ H Q
Sbjct: 675 TLEKLDVKQTELESLSSE-LSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQ 733
Query: 235 QK-----KDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEEL 289
Q+ K+ E+ Q+ L++++++LE K+ + + + + L+A + E EL
Sbjct: 734 QQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGEL 793
Query: 290 QRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQ 349
Q+ ++ + S + E+ + QLQ K+ LE E +++L + A Q
Sbjct: 794 QQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETE-----RILLTKQVAEVEAQ 848
Query: 350 EQKVVLEENGEKNQVQLGKLEATIKSLSAELLKAN-EIIKKLQGDLKTLMGKLKLKNTVT 408
++ V E + K QVQ L +L K N E+ +K++ + KL+ N
Sbjct: 849 KKDVCTELDAHKIQVQ---------DLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQ 899
Query: 409 IQQEKLLAEKEEKL----QKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLL 464
Q +++L EKE + + ++KE++ + Q L KE + L E+ E K E+ + +
Sbjct: 900 EQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKV 959
Query: 465 KNNEK-LITWLNKELNENQLVRKQDV 489
K K + L K+L + + K+++
Sbjct: 960 KQKAKEMQETLKKKLLDQEAKLKKEL 985
Score = 72.0 bits (175), Expect = 2e-12
Identities = 88/344 (25%), Positives = 157/344 (45%), Gaps = 51/344 (14%)
Query: 158 KCSKEEKLSLMQSLDDATKQL-DFTRKTLAEKKQELDKLRN-EWASHTAALTNK---HSQ 212
K S+EE++SL Q L +++ D +K+ E+ +L KL E A LT K +
Sbjct: 446 KTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTRER 505
Query: 213 ELTNEKEKALQ-AQVQY----QQQHEQQKKDLEILH-----------------QQNIHQL 250
E + + AL+ +Q +Y Q++ +Q+ LE L QQ
Sbjct: 506 EFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETY 565
Query: 251 QNRLSELEAA-NKDLTERKYKGDSTIRELKAKLSGVEEEL----QRTKQEVLSLRRENST 305
+ R+ ELE++ K L E K + L+A+ + +E+ ++ K E+ SL+ +
Sbjct: 566 RTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDA 625
Query: 306 LDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQ 365
L E + K Q QT++ L ++ + + + +L+ KE +EE EK +
Sbjct: 626 LWTEKLQVLKQ--QYQTEMEKLREKCEQEKETLLKDKEIIFQAH-----IEEMNEKTLEK 678
Query: 366 LGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKE 425
L + ++SLS+EL + + KL+ +L L Q +K+ E E K+ ++
Sbjct: 679 LDVKQTELESLSSELSEVLKARHKLEEELSVLKD----------QTDKMKQELEAKMDEQ 728
Query: 426 QKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEK 469
+ Q S+ IKE EV +Q +A ++ + + LLK +K
Sbjct: 729 KNHHQQQVDSI-IKEHEV-SIQRTEKALKDQINQLELLLKERDK 770
Score = 66.6 bits (161), Expect = 7e-11
Identities = 89/377 (23%), Positives = 172/377 (45%), Gaps = 64/377 (16%)
Query: 162 EEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKL-------RNEWASHTAALTNKHS--Q 212
EE+ +L S AT QL+ + K +++ L + E + A + K S
Sbjct: 1283 EEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCIT 1342
Query: 213 ELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQ----NIHQLQNR--LSELEAA----NK 262
+L E + + A +++ +++K ++ L +Q N+ QLQN LSE EAA K
Sbjct: 1343 QLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNV-QLQNSISLSEKEAAISSLRK 1401
Query: 263 DLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEK----EKHVN 318
E K + +++L K+ + +E ++V + S + + + V
Sbjct: 1402 QYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVK 1461
Query: 319 QLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQ----KVVLEENGEKNQVQLGKLEATIK 374
+LQ ++ + +E +KD+ + KE D ++ K +E++ K + + LE +K
Sbjct: 1462 ELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELK 1521
Query: 375 SLSAELLKA--------------NEIIKKL--QGDL--KTLMGKLKLKNTVTIQQEKLLA 416
S +A +++ NE++K Q D+ K L+ KL+ + +++ +
Sbjct: 1522 SQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVK 1581
Query: 417 EKEEK--------------LQKEQKELQDVGQSLRIKEQEVCKLQEQLEA-TVKKLEESK 461
E EEK L+ ++KEL+ V S++ KE+E+ L+++LE+ + KL E K
Sbjct: 1582 EAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELK 1641
Query: 462 QLLKNNEKLITWLNKEL 478
+ E+ I + K+L
Sbjct: 1642 ---RKAEQKIAAIKKQL 1655
Score = 65.5 bits (158), Expect = 2e-10
Identities = 75/358 (20%), Positives = 156/358 (43%), Gaps = 32/358 (8%)
Query: 126 VETNPFKHLTHLSLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFTRKTL 185
++ N F + LK+L D L LK + EE SL S + + K L+
Sbjct: 1147 LKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEF 1206
Query: 186 AEKKQELDKLRNEWASHTAALTNKHSQELTN---EKEKALQAQVQYQQQHEQQKKDLEIL 242
+ +EL + T AL + EL N K A+ +++ + Q + K+ ++
Sbjct: 1207 KKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLI 1266
Query: 243 HQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRE 302
+ SELEA + LTE + + + ++ +L E +++ K ++ SL E
Sbjct: 1267 KTCTV-------SELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTE 1319
Query: 303 NSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGE-- 360
L E +++ ++ ++ + L++E+ + V KE ++E+KV + +
Sbjct: 1320 KEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKE---ELKEKKVEISSLSKQL 1376
Query: 361 -------KNQVQLGKLEATIKSLSAELLKAN-EIIKKLQGDLKTLMGKLKLKNTVTIQQ- 411
+N + L + EA I SL + + E++ ++Q DL + L + ++Q
Sbjct: 1377 TDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQ-DLSFKVDTLSKEKISALEQV 1435
Query: 412 ---EKLLAEKEEKLQ----KEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQ 462
+E ++K Q + Q ++++ L +K +E + EQ+ ++L++ +
Sbjct: 1436 DDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNK 1493
Score = 62.8 bits (151), Expect = 1e-09
Identities = 137/621 (22%), Positives = 247/621 (39%), Gaps = 157/621 (25%)
Query: 7 HQLVPLQVKCKDCEERRVSIRMSIELQSVSNPVHRKDLVIRLTDDTDPFFLYNLVISEE- 65
++L LQ + + R + + S+E N KDL + L + + V+ E+
Sbjct: 553 NKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKH 612
Query: 66 --DFQSLKFQQGLLVDFLAFPQKFIDLLQQCTQEHAKEIPRFLLQLVSPAAIL--DNSPA 121
+ +SLK QQ L + + LQ Q++ E+ + + L D
Sbjct: 613 KTELESLKHQQDAL---------WTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEII 663
Query: 122 FLNVVETNPFKHLTHLSLKL--LPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQ-- 177
F +E K L L +K L E+ + L K EE+LS+++ D KQ
Sbjct: 664 FQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKL--EEELSVLKDQTDKMKQEL 721
Query: 178 -------------------------LDFTRKTLAEKKQELDKLRNE----WASHTAALTN 208
+ T K L ++ +L+ L E H A + N
Sbjct: 722 EAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVEN 781
Query: 209 KHS----------------------QELTNEKEKALQAQVQYQQQH-------------- 232
+ Q T+E+ KA + Q+ QQ
Sbjct: 782 LEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQ 841
Query: 233 ----EQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEE 288
E QKKD+ + Q+Q+ + +LE N ++ E+K K + + E +KL +E
Sbjct: 842 VAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEM-EQKVKSLTQVYE--SKLEDGNKE 898
Query: 289 LQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEI---------------KD 333
++TKQ + + +EN L + +K K + L K++ E I K
Sbjct: 899 QEQTKQ--ILVEKENMILQMREGQK-KEIEILTQKLSAKEDSIHILNEEYETKFKNQEKK 955
Query: 334 KDQLVLRTKEAFDTIQ----EQKVVLEENGEKNQVQLGKLEATIKSLSAELLKAN----- 384
+++ + KE +T++ +Q+ L++ E ++L + E + E+ +AN
Sbjct: 956 MEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGIS 1015
Query: 385 ------EIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEE-------KLQKEQKELQD 431
E +K Q + T + + +L + ++I ++KL + EE +LQ++++E+ +
Sbjct: 1016 DAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAE 1075
Query: 432 VGQSLRI---------------KEQEVCK------LQEQLE---ATVKKLEESKQLLKNN 467
+ Q + + KE+ V + LQEQL+ A V L + + LK +
Sbjct: 1076 LKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAH 1135
Query: 468 -EKLITWLNKELNENQLVRKQ 487
EKL LNK L EN +++Q
Sbjct: 1136 LEKLEVDLNKSLKENTFLQEQ 1156
Score = 62.4 bits (150), Expect = 1e-09
Identities = 81/347 (23%), Positives = 160/347 (46%), Gaps = 47/347 (13%)
Query: 161 KEEKLSLM-QSLDDATKQLDFTRKTLAEKKQELDK----LRNEWASHTAALTN--KHSQE 213
K+E+++L+ + LD K+ D + + + K +++K L E S TA + H +
Sbjct: 1477 KDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQ 1536
Query: 214 LTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDS 273
T E E + Y QQ KD+E H++ + +LQ+ ++L E K D+
Sbjct: 1537 KTIEIESLNEVLKNYNQQ-----KDIE--HKELVQKLQHF--------QELGEEK---DN 1578
Query: 274 TIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHV----NQLQTKVAVLEQ 329
++E + K+ +E ++ K E+ + ++E +++ KE+ + ++L+++ A
Sbjct: 1579 RVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLA 1638
Query: 330 EIKDK-DQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIK 388
E+K K +Q + K+ + E+K + G ++ L +L ++ E+ E +K
Sbjct: 1639 ELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESH--LSELNTKLQEREREVHILEEKLK 1696
Query: 389 KLQGDL-KTLMGKLKLKNTV--TIQQE--------KLLAEKEEKLQK----EQKELQDVG 433
++ +TL+ KN T Q+E K EK LQ+ ++K LQ VG
Sbjct: 1697 SVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVG 1756
Query: 434 QSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNE 480
Q +++ Q + + KLE ++ ++ +I L +EL E
Sbjct: 1757 QEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEE 1803
Score = 55.8 bits (133), Expect = 1e-07
Identities = 58/266 (21%), Positives = 126/266 (47%), Gaps = 34/266 (12%)
Query: 244 QQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAK----LSGVEEELQRTKQEVLSL 299
++++ + + SEL A + L K K + + + K ++ + EELQ +Q L
Sbjct: 147 ERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLRRIAELREELQMDQQAKKHL 206
Query: 300 RRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKD--KDQLVLRTKEAFDTIQEQKVVLEE 357
+ E D EK+++++ LQT+V++L+Q +++ + VL+ + Q + EE
Sbjct: 207 QEE---FDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQLEP-QAEVFTKEE 262
Query: 358 NGEKN---QVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKL 414
N E + V+ G T+++L + + ++K+ + +T+ + +T ++E L
Sbjct: 263 NPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCK---ETIQSHKEQCTLLTSEKEAL 319
Query: 415 LAEKEEKLQKEQK--------------ELQDVGQSLRIKEQE----VCKLQEQLEATVKK 456
+ +E+LQ+ +K +L+D + EQ+ + + + Q+ T++
Sbjct: 320 QEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEM 379
Query: 457 LEESKQLLKNNEKLITWLNKELNENQ 482
EE L++ K +T +EL E +
Sbjct: 380 KEEEIAQLRSRIKQMTTQGEELREQK 405
Score = 55.5 bits (132), Expect = 2e-07
Identities = 90/412 (21%), Positives = 173/412 (41%), Gaps = 103/412 (25%)
Query: 174 ATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHE 233
+ K L+ ++ + ++ L + + SH T LT+EKE ALQ Q+ + Q
Sbjct: 277 SVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTL-----LTSEKE-ALQEQLDERLQEL 330
Query: 234 QQKKDLEI----------------------------------------LHQQNIHQLQNR 253
++ KDL + + ++ I QL++R
Sbjct: 331 EKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSR 390
Query: 254 LSELEAANKDLTERKYKGDSTI------------------RELKAKLS------------ 283
+ ++ ++L E+K K + R+LKA++
Sbjct: 391 IKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEE 450
Query: 284 ---GVEEELQRTKQEVLSLRRENSTLDV----ECHEKE--KHVNQLQTKVAVLEQEIKDK 334
+++EL R KQEV+ + +++S + + HEKE + +L K+ E+E +++
Sbjct: 451 ERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQ 510
Query: 335 DQLVLR------TKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIK 388
++ L K + + Q++ + LEE + + L + E ++ L E I
Sbjct: 511 MKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRIL 570
Query: 389 KLQGDLKTLMGKLKLKN---TVTIQQEKLLAEKE-----EKLQKEQKELQDVGQSLRIKE 440
+L+ L+ + + K ++ V ++ EK KE EK + E + L+ +L ++
Sbjct: 571 ELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEK 630
Query: 441 QEVCKLQEQ--LEATVKKLEESKQ-LLKNNEKLITWLNKELNENQLVRKQDV 489
+V K Q Q +E +K E+ K+ LLK+ E + +E+NE L K DV
Sbjct: 631 LQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTL-EKLDV 681
Score = 55.1 bits (131), Expect = 2e-07
Identities = 79/321 (24%), Positives = 136/321 (42%), Gaps = 39/321 (12%)
Query: 162 EEKLSLMQSLDDATKQLDFTRKTLAEKKQ----ELDKLRNEWASHTAALT----NKHSQ- 212
+EK Q L+ K+LD L +K+ E+++L +++ A NK ++
Sbjct: 1843 QEKELTCQILEQKIKELD---SCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTEL 1899
Query: 213 --ELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYK 270
E T EK K+ Q + E Q DLE + Q E+ KDL + +
Sbjct: 1900 LEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKE 1959
Query: 271 GDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQE 330
+ LK + EE + +QE L L + NSTL ++ + + T++A EQE
Sbjct: 1960 HQQELEILKKEYDQEREEKIKQEQEDLEL-KHNSTL-------KQLMREFNTQLAQKEQE 2011
Query: 331 IKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGK--------LEATIKSLSAELLK 382
++ + KE + QE + L E+ ++ QL K L+ T K L
Sbjct: 2012 LE------MTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDA 2065
Query: 383 ANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQD---VGQSLRIK 439
E + DL+T + +L+ K ++QE+ + + Q +L + ++K
Sbjct: 2066 REEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLK 2125
Query: 440 EQEVCKLQEQLEATVKKLEES 460
EQE + LE +KK E++
Sbjct: 2126 EQEFREQIHNLEDRLKKYEKN 2146
Score = 50.8 bits (120), Expect = 4e-06
Identities = 67/335 (20%), Positives = 141/335 (42%), Gaps = 23/335 (6%)
Query: 159 CSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEK 218
C KEE + L + + D T L E+ ++ N A L H ++L +
Sbjct: 1085 CEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKL-KAHLEKLEVDL 1143
Query: 219 EKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIREL 278
K+L+ Q+Q + K E ++ + +L ++L + + L K + ++ +
Sbjct: 1144 NKSLKENTFLQEQLVELKMLAEE-DKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDK 1202
Query: 279 KAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLV 338
+ + EEL Q + ++ + L+ + +E +N +K + I
Sbjct: 1203 SLEFKKLSEEL--AIQLDICCKKTEALLEAKTNEL---INISSSKTNAILSRISHCQHRT 1257
Query: 339 LRTKEAF----DTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDL 394
+ KEA T+ E + L + E+ L + + + +L + IK ++ D+
Sbjct: 1258 TKVKEALLIKTCTVSELEAQLRQLTEEQNT----LNISFQQATHQLEEKENQIKSMKADI 1313
Query: 395 KTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQD-------VGQSLRIKEQEVCKLQ 447
++L+ + + Q++ +EKE + + +KEL + + + L+ K+ E+ L
Sbjct: 1314 ESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLS 1373
Query: 448 EQLEATVKKLEESKQLLKNNEKLITWLNKELNENQ 482
+QL +L+ S L E I+ L K+ +E +
Sbjct: 1374 KQLTDLNVQLQNSIS-LSEKEAAISSLRKQYDEEK 1407
Score = 50.1 bits (118), Expect = 7e-06
Identities = 80/348 (22%), Positives = 146/348 (41%), Gaps = 61/348 (17%)
Query: 155 GCLKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQEL 214
GC++ + EEK+S++Q + L EK++ L ++ E + H +
Sbjct: 1728 GCVQKTYEEKISVLQ-------------RNLTEKEKLLQRVGQE----KEETVSSHFEMR 1770
Query: 215 TNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDST 274
+E+ ++ + +QHE Q I H Q + +N+ L A K G +
Sbjct: 1771 CQYQERLIKLEHAEAKQHEDQSM---IGHLQEELEEKNKKYSLIVAQH---VEKEGGKNN 1824
Query: 275 IRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQL------QTKVAVLE 328
I + K L V +++Q+T QE ++ C E+ + +L Q +V +E
Sbjct: 1825 I-QAKQNLENVFDDVQKTLQEK----------ELTCQILEQKIKELDSCLVRQKEVHRVE 1873
Query: 329 QEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQ-------LGKLEATIKSLSAELL 381
E L+ + D + +LEEN E+ L +EA L +L
Sbjct: 1874 MEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLA 1933
Query: 382 KANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQ 441
A +KL ++ L L++ QQE + +KE ++E+K Q EQ
Sbjct: 1934 GAEREKQKLGKEIVRLQKDLRMLRKEH-QQELEILKKEYDQEREEKIKQ---------EQ 1983
Query: 442 EVCKLQEQLEATVKKL--EESKQLLKNNEKLITWLNKELNENQLVRKQ 487
E +L+ +T+K+L E + QL + ++L + + +N+ Q V +
Sbjct: 1984 EDLELKH--NSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAE 2029
Score = 48.5 bits (114), Expect = 2e-05
Identities = 75/331 (22%), Positives = 140/331 (42%), Gaps = 66/331 (19%)
Query: 214 LTNEKEKALQ--AQVQYQQQHEQQ-KKDLEILHQQNIHQLQNRLSELEAANKDLTERKYK 270
L+ ++K+L+ A+++ + Q +QQ KK L+ ++ + +S L+ L +R
Sbjct: 178 LSQSQDKSLRRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRN 237
Query: 271 GDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVE-CHEKEKHVNQLQTKVAVLEQ 329
G + LK Q Q + + EN D E E V L+T L+Q
Sbjct: 238 GPMNVDVLKPLP-------QLEPQAEVFTKEENPESDGEPVVEDGTSVKTLET----LQQ 286
Query: 330 EIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGK----LE-------ATIKSLSA 378
+K ++ L+ R KE + +EQ +L E Q QL + LE A L
Sbjct: 287 RVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLIT 346
Query: 379 ELLKANEIIKKLQGDLKTLMGKLKLK-------------------NTVTIQQEKLLAEKE 419
+L A +I++L+ D ++ + K + +T Q E+L +KE
Sbjct: 347 QLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKE 406
Query: 420 EKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQ----------------- 462
+ + +EL+ + + E+ KL+ +++ +K +E++ +
Sbjct: 407 KSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEV 466
Query: 463 ---LLKNNEKLITWLNKELNENQLVRKQDVL 490
+ K++E+ I L K L+E +L RK+ L
Sbjct: 467 VDVMKKSSEEQIAKLQK-LHEKELARKEQEL 496
Score = 47.8 bits (112), Expect = 3e-05
Identities = 69/331 (20%), Positives = 137/331 (41%), Gaps = 38/331 (11%)
Query: 162 EEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKA 221
E++ ++Q + K+++ + L+ K+ + L E+ T + E +K K
Sbjct: 908 EKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEY--ETKFKNQEKKMEKVKQKAKE 965
Query: 222 LQAQVQYQ--QQHEQQKKDLEI------------------LHQQNIHQLQNRLSELEAAN 261
+Q ++ + Q + KK+LE + Q N + + +S LE
Sbjct: 966 MQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQ 1025
Query: 262 KD----LTE-RKYKGDSTIRELKAKLSGVEEELQR--------TKQEVLSLRRENSTLDV 308
K+ LTE + + + I + KL+ EELQ +QEV L+++
Sbjct: 1026 KEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGC 1085
Query: 309 ECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGK 368
E E K + L+ + + + + + + + +++ + + L+ + EK +V L K
Sbjct: 1086 EKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNK 1145
Query: 369 LEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEK-LQKEQK 427
L +L++ + ++ + + L KLK + Q K EK K L+ +
Sbjct: 1146 SLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDE-EFQSLKSSHEKSNKSLEDKSL 1204
Query: 428 ELQDVGQSLRIKEQEVCKLQEQ-LEATVKKL 457
E + + + L I+ CK E LEA +L
Sbjct: 1205 EFKKLSEELAIQLDICCKKTEALLEAKTNEL 1235
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 78.6 bits (192), Expect = 2e-14
Identities = 85/346 (24%), Positives = 153/346 (44%), Gaps = 50/346 (14%)
Query: 181 TRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKA-LQAQVQYQQQHEQQKKDL 239
T K +A K+E +K + E A A + +T +EK LQ QVQ + D
Sbjct: 849 TEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEA-------DA 901
Query: 240 EILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSL 299
++ QL +LEA K++TER + EL AK +E+E K+++ L
Sbjct: 902 LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 961
Query: 300 RRENSTLDVECHEKEKHVNQLQTKVAVLEQEI----KDKDQLVLRTKEAFDTIQ--EQKV 353
+ ++ E H E V L ++A L++ I K+K L ++ D +Q E KV
Sbjct: 962 ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKV 1021
Query: 354 -VLEENGEKNQVQLGKLEATI---KSLSAELLKA-------------------------N 384
L + K + Q+ LE ++ K L +L +A N
Sbjct: 1022 NTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLN 1081
Query: 385 EIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVC 444
E +KK + ++ L GK++ + + IQ +K + E + ++++ ++E++ S E++
Sbjct: 1082 EKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1141
Query: 445 KLQEQLEATVKKLEESK-------QLLKNNEKLITWLNKELNENQL 483
L +LE ++LEE+ ++ K E + ++L E+ L
Sbjct: 1142 DLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTL 1187
Score = 62.4 bits (150), Expect = 1e-09
Identities = 70/347 (20%), Positives = 156/347 (44%), Gaps = 25/347 (7%)
Query: 164 KLSLMQSLDDATKQLDFTRKTLAEK---KQELDKLRNEWASHTAALTNKHSQELTNEKEK 220
K +L +L A D R+ E+ K EL + ++ S A K+ + E+
Sbjct: 1330 KSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEE 1389
Query: 221 ALQAQVQYQQQHEQQKKDLEILH------QQNIHQLQNRLSEL-------EAANKDLTER 267
+A+ + Q+ + ++ +E ++ ++ +LQN + +L AA L ++
Sbjct: 1390 LEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKK 1449
Query: 268 KYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVL 327
+ D + E K K + EL+ +++E SL E + E H+ L+ + L
Sbjct: 1450 QRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNL 1509
Query: 328 EQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEII 387
+QEI D + + + +++ K L+ + Q L + EA+++ ++L+ +
Sbjct: 1510 QQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLEL 1569
Query: 388 KKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKE-QKELQDVGQSLRIK---EQEV 443
+++ ++ K+ K+ Q ++ E +Q E++ +LRIK E ++
Sbjct: 1570 NQVKSEIDR---KIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDL 1626
Query: 444 CKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQDVL 490
+++ QL ++ E+ + L+N + ++ + +L+ + +R QD L
Sbjct: 1627 NEMEIQLNHANRQAAEALRNLRNTQGILK--DTQLHLDDAIRGQDDL 1671
Score = 58.5 bits (140), Expect = 2e-08
Identities = 85/384 (22%), Positives = 161/384 (41%), Gaps = 74/384 (19%)
Query: 162 EEKLSLMQSLDDATK-QLDFTRKTLAE---KKQELDKLRNEWASHTAALTNKHSQELTNE 217
EE ++ AT Q++ +K AE +++L++ + + AAL KH+ +
Sbjct: 1148 EEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAEL 1207
Query: 218 KEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRE 277
E+ Q + +Q+ E++K +L++ I+ L + + + A + + + + E
Sbjct: 1208 GEQIDSLQ-RVKQKLEKEKSELKM----EINDLASNMETVSKAKANFEKMCRTLEDQLSE 1262
Query: 278 LKAKLSGVEEELQRTKQEVLS----LRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKD 333
+K K EEE QR E+ + L E+ + EK+ V+QL Q+I++
Sbjct: 1263 IKTK----EEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEE 1318
Query: 334 -KDQLVLRTK--------------------EAFDTIQEQKVVLEENGEKNQVQLG----- 367
K QL TK E ++ QE K L+ K ++
Sbjct: 1319 LKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTK 1378
Query: 368 ----------KLEATIKSLSAELLKANEII--------------KKLQGDLKTLMGKLKL 403
+LE K L+ L A E + ++LQ +++ LM ++
Sbjct: 1379 YETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVER 1438
Query: 404 KNTVTI-------QQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKK 456
N I +K+LAE ++K ++ Q EL+ + R E+ K++ E ++
Sbjct: 1439 SNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDH 1498
Query: 457 LEESKQLLKNNEKLITWLNKELNE 480
LE K+ KN ++ I+ L +++ E
Sbjct: 1499 LETLKRENKNLQQEISDLTEQIAE 1522
Score = 57.4 bits (137), Expect = 4e-08
Identities = 79/354 (22%), Positives = 147/354 (41%), Gaps = 55/354 (15%)
Query: 163 EKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALT--NKHSQELTNEKEK 220
+K L + K +D TLA+ ++E N+ + T + ++ +LT EK K
Sbjct: 943 KKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEK-K 1001
Query: 221 ALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLT---ERKYKGDSTIRE 277
ALQ + H+Q DL+ + + ++ L ++LE DL E++ K +
Sbjct: 1002 ALQ------EAHQQTLDDLQ-MEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLER 1054
Query: 278 LKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQL 337
K KL G +L+ ++ + + L+ + +KE ++ LQ K I+D+ L
Sbjct: 1055 AKRKLEG---DLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGK-------IEDEQAL 1104
Query: 338 VLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIK--------- 388
++ ++ +Q + LEE E + K E LS EL + +E ++
Sbjct: 1105 AIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQ 1164
Query: 389 ------------KLQGDLK-------TLMGKLKLKNTVTI----QQEKLLAEKEEKLQKE 425
K++ DL+ L+ K+ ++ +Q L ++KL+KE
Sbjct: 1165 IEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKE 1224
Query: 426 QKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELN 479
+ EL+ L + V K + E + LE+ +K E+ L EL+
Sbjct: 1225 KSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELS 1278
Score = 52.4 bits (124), Expect = 1e-06
Identities = 67/354 (18%), Positives = 158/354 (44%), Gaps = 45/354 (12%)
Query: 165 LSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQA 224
L + L+ ++D + +AEK +ELD+L+ ++ + E+ + + AL+
Sbjct: 1563 LRIQLELNQVKSEID---RKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRND-ALRI 1618
Query: 225 QVQYQQQHEQQKKDLEILHQQNIHQLQN-------------RLSELEAANKDLTE----- 266
+ + + + + L ++Q L+N L + DL E
Sbjct: 1619 KKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMV 1678
Query: 267 --RKYKGDSTIRELKAKLSGVEEELQRTKQEVLS-------LRRENSTLDVECHEKEKHV 317
R + + EL+A L E + +QE+L L +N++L + E +
Sbjct: 1679 ERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1738
Query: 318 NQLQTKVAVLEQEIKDKDQLVLRTKEAFD--TIQEQKVVLEENGEKNQVQLGK-LEATIK 374
+Q+Q ++ + QE ++ ++ + K+A + +++ E++ + ++ K +E T+K
Sbjct: 1739 SQIQGEMEDIVQEARNAEE---KAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVK 1795
Query: 375 SLSAELLKANEI--------IKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQ 426
L L +A ++ I+KL+ ++ L +++ + ++ K L + E ++++
Sbjct: 1796 DLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELT 1855
Query: 427 KELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNE 480
+ ++ +++ + V KLQ +++A ++ EE+++ N L EL E
Sbjct: 1856 YQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEE 1909
Score = 51.2 bits (121), Expect = 3e-06
Identities = 64/358 (17%), Positives = 152/358 (42%), Gaps = 17/358 (4%)
Query: 123 LNVVETNPFKHLTHLSLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFTR 182
L + + KH T +K L + + +A K K + + Q+LDD + D
Sbjct: 963 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVN 1022
Query: 183 KTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEIL 242
TL + K +L++ ++ + K +L K K L+ ++ Q+ ++ +
Sbjct: 1023 -TLTKAKTKLEQQVDDLEG-SLEQEKKLCMDLERAKRK-LEGDLKLAQESTMDTENDKQQ 1079
Query: 243 HQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRE 302
+ + + + +S L+ +D + I+EL+A++ +EEE++ + ++
Sbjct: 1080 LNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQ 1139
Query: 303 NSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKN 362
S L E E + + + + Q+ + K + Q+ + LEE+ ++
Sbjct: 1140 RSDLSRELEEISERLEEAGGATSA---------QIEMNKKREAE-FQKMRRDLEESTLQH 1189
Query: 363 QVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKL 422
+ L AEL + + +++++ L+ +LK++ + +++ +
Sbjct: 1190 EATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANF 1249
Query: 423 QKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLE----ESKQLLKNNEKLITWLNK 476
+K + L+D ++ KE+E +L +L A +L E + L + +++ L++
Sbjct: 1250 EKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSR 1307
Score = 49.3 bits (116), Expect = 1e-05
Identities = 52/272 (19%), Positives = 124/272 (45%), Gaps = 25/272 (9%)
Query: 209 KHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERK 268
K + + +QA+V+ + ++ + + +Q + R+ L N L K
Sbjct: 1672 KEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTK 1731
Query: 269 YKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLE 328
K ++ I +++ ++ + +E + +++ + + + E +++ L+ +E
Sbjct: 1732 KKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 1791
Query: 329 QEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAEL-------L 381
Q +KD L LR EA EQ L G K Q+Q KLEA ++ L +E+ +
Sbjct: 1792 QTVKD---LQLRLDEA-----EQ---LALKGGKKQIQ--KLEARVRELESEVESEQKHNV 1838
Query: 382 KANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQ 441
+A + ++K + +K L + + ++ + L+ + + K++ +++ ++ + +
Sbjct: 1839 EAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLA 1898
Query: 442 EVCKLQEQLE-----ATVKKLEESKQLLKNNE 468
+ KLQ +LE A + + + +K +K+ E
Sbjct: 1899 KFRKLQHELEEAKERADIAESQVNKLRVKSRE 1930
Score = 43.1 bits (100), Expect = 8e-04
Identities = 49/214 (22%), Positives = 96/214 (44%), Gaps = 29/214 (13%)
Query: 281 KLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLR 340
K + E+E+ K+E + E + + + E E+ + L + L+ +++ + +
Sbjct: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALAD 904
Query: 341 TKEAFDTIQEQKVVLE-------ENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGD 393
+E D + + K+ LE E E + +L A + L E + +KK D
Sbjct: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE----LKKDIDD 960
Query: 394 LKTLMGKLKLKNTVTIQQEKLLAEKE-------EKLQKEQKELQDVGQ----SLRIKEQE 442
L+ + K++ + T + K L E+ KL KE+K LQ+ Q L+++E +
Sbjct: 961 LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDK 1020
Query: 443 V-------CKLQEQLEATVKKLEESKQLLKNNEK 469
V KL++Q++ LE+ K+L + E+
Sbjct: 1021 VNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLER 1054
Score = 40.8 bits (94), Expect = 0.004
Identities = 41/171 (23%), Positives = 82/171 (47%), Gaps = 12/171 (7%)
Query: 323 KVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEEN-----GEKNQVQLGKLEATIKSLS 377
K A E+E+ + + +TKE + ++ LEE EKN +QL +++A +L+
Sbjct: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQL-QVQAEADALA 903
Query: 378 AELLKANEIIK-KLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSL 436
+ +++IK K+Q L K+K +E++ AE K +K + E ++ + +
Sbjct: 904 DAEERCDQLIKTKIQ-----LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 958
Query: 437 RIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQ 487
E + K++++ AT K++ + + ++ I L KE Q +Q
Sbjct: 959 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQ 1009
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 78.2 bits (191), Expect = 2e-14
Identities = 86/346 (24%), Positives = 149/346 (43%), Gaps = 50/346 (14%)
Query: 181 TRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKA-LQAQVQYQQQHEQQKKDL 239
T K +A K+E K ++E A A + +T KEK LQ QVQ + D
Sbjct: 848 TEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQ-------SEADS 900
Query: 240 EILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSL 299
++ QL +LEA K++TER + + EL AK +E+E K+++ L
Sbjct: 901 LADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDL 960
Query: 300 RRENSTLDVECHEKEKHVNQLQTKVAVLEQEI----KDKDQLVLRTKEAFDTIQ--EQKV 353
+ ++ E H E V L ++A L++ I K+K L ++ D +Q E KV
Sbjct: 961 ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKV 1020
Query: 354 -VLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLK----------------- 395
+L + K + Q+ LE +++ + +KL+GDLK
Sbjct: 1021 NILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLD 1080
Query: 396 -----------TLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVC 444
L+ K++ + V IQ +K + E + ++++ +E++ S E++
Sbjct: 1081 EKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRS 1140
Query: 445 KLQEQLEATVKKLEES-------KQLLKNNEKLITWLNKELNENQL 483
L +LE ++LEE+ +L K E L ++L E L
Sbjct: 1141 DLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATL 1186
Score = 63.9 bits (154), Expect = 4e-10
Identities = 72/341 (21%), Positives = 154/341 (45%), Gaps = 29/341 (8%)
Query: 168 MQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQV- 226
M L + L ++ L ++K EL ++ +S+ A++ + ++L+ QV
Sbjct: 1203 MAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGN--LEKMCRSLEDQVS 1260
Query: 227 QYQQQHEQQKKDLEILHQQNIH------QLQNRLSELEAANKDLTERKYKGDSTIRELKA 280
+ + + E+Q++ + L Q + +L E +A L+ K I ELK
Sbjct: 1261 ELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKH 1320
Query: 281 KLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLR 340
+L + + S R + L + E+++ +LQ ++ E+ R
Sbjct: 1321 QLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQ-----WR 1375
Query: 341 TKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGK 400
TK D IQ + LEE +K +L + E +++++A+ + ++LQ +++ LM
Sbjct: 1376 TKYETDAIQRTEE-LEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLD 1434
Query: 401 LKLKNTVTI-------QQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEAT 453
++ N +K+L+E ++K ++ Q EL+ + R E+ K++ E +
Sbjct: 1435 VERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEES 1494
Query: 454 VKKLEESKQLLKNNEKLITWL-------NKELNENQLVRKQ 487
+ +LE ++ KN ++ I+ L K+++E + ++KQ
Sbjct: 1495 LDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQ 1535
Score = 59.3 bits (142), Expect = 1e-08
Identities = 73/375 (19%), Positives = 158/375 (42%), Gaps = 42/375 (11%)
Query: 157 LKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTN 216
L+ + E +L Q + D T+Q+ K + E ++ ++ E AAL + L +
Sbjct: 1498 LETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEA-SLEH 1556
Query: 217 EKEKALQAQVQYQQ----------QHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTE 266
E+ K L+ Q++ Q + +++ L+ H + + +Q+ L + D
Sbjct: 1557 EEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALR 1616
Query: 267 RKYKGDSTIRELKAKLS--------------GVEEELQRTKQEVLSLRRENSTLDVECHE 312
K K + + E++ +L+ + L+ T+ + R L +
Sbjct: 1617 VKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAI 1676
Query: 313 KEKHVNQLQTKV----AVLEQEIKDK---DQLVLRTKEAFDTIQEQKVVLEENGEKNQVQ 365
E+ N LQ ++ A LEQ + + +Q +L E + Q L +K +
Sbjct: 1677 VERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLEND 1736
Query: 366 LGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKE 425
+ +L++ ++ + E A E KK D + +LK + + E++ E+ ++
Sbjct: 1737 VSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDL 1796
Query: 426 QKELQDVGQ--------SLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKE 477
Q L + Q ++ E V +L+ ++E K+ E+ + L+ +E+ + L +
Sbjct: 1797 QHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQ 1856
Query: 478 LNENQ--LVRKQDVL 490
E++ ++R QD++
Sbjct: 1857 TEEDRKNVLRLQDLV 1871
Score = 53.5 bits (127), Expect = 6e-07
Identities = 65/332 (19%), Positives = 143/332 (43%), Gaps = 43/332 (12%)
Query: 164 KLSLMQSLDDATKQLDFTRKTLAEK---KQELDKLRNEWASHTAALTNKHSQELTNEKEK 220
K +L +L + D R+ E+ K EL + ++ S A K+ + E+
Sbjct: 1329 KNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEE 1388
Query: 221 ALQAQVQYQQQHEQQKKDLEILH------QQNIHQLQNRLSEL-------EAANKDLTER 267
+A+ + Q+ ++ ++ +E ++ ++ +LQN + +L AA L ++
Sbjct: 1389 LEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKK 1448
Query: 268 KYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVL 327
+ D + E K K + EL+ +++E SL E + E + L+ + L
Sbjct: 1449 QRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNL 1508
Query: 328 EQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEII 387
+QEI D + + + +++ K +E+ + Q L + EA+++ ++L
Sbjct: 1509 QQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKIL------ 1562
Query: 388 KKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQ 447
++Q +L N V + ++ +AEK+E ++ Q R + V +Q
Sbjct: 1563 -RIQLEL----------NQVKSEVDRKIAEKDE----------EIDQLKRNHTRVVETMQ 1601
Query: 448 EQLEATVKKLEESKQLLKNNEKLITWLNKELN 479
L+A ++ ++ ++ K E + + +LN
Sbjct: 1602 STLDAEIRSRNDALRVKKKMEGDLNEMEIQLN 1633
Score = 53.5 bits (127), Expect = 6e-07
Identities = 71/356 (19%), Positives = 160/356 (44%), Gaps = 49/356 (13%)
Query: 165 LSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQA 224
L + L+ ++D + +AEK +E+D+L+ +HT + S + +
Sbjct: 1562 LRIQLELNQVKSEVD---RKIAEKDEEIDQLKR---NHTRVVETMQSTLDAEIRSRNDAL 1615
Query: 225 QVQYQQQHEQQKKDLEILH---------------QQNIHQLQNRLSELEAANKDLTE--- 266
+V+ + + + + ++++ H Q + + Q L + +DL E
Sbjct: 1616 RVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLA 1675
Query: 267 ----RKYKGDSTIRELKAKLSGVEEELQRTKQEVLS-------LRRENSTLDVECHEKEK 315
R + I EL A L E + +QE+L L +N++L + E
Sbjct: 1676 IVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLEN 1735
Query: 316 HVNQLQTKVAVLEQEIKDKDQLVLRTKEAFD--TIQEQKVVLEENGEKNQVQLGK-LEAT 372
V+QLQ++V + QE ++ ++ + K+A + +++ E++ + ++ K LE T
Sbjct: 1736 DVSQLQSEVEEVIQESRNAEE---KAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQT 1792
Query: 373 IKSLSAELLKANEI--------IKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQK 424
+K L L +A ++ I+KL+ ++ L G+++ + + K L + E ++++
Sbjct: 1793 VKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKE 1852
Query: 425 EQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNE 480
+ ++ +++ + V KLQ ++++ ++ EE+++ N L EL E
Sbjct: 1853 LTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEE 1908
Score = 52.4 bits (124), Expect = 1e-06
Identities = 71/365 (19%), Positives = 153/365 (41%), Gaps = 31/365 (8%)
Query: 123 LNVVETNPFKHLTHLSLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLD--- 179
L + + KH T +K L + + +A K K + + Q+LDD + D
Sbjct: 962 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVN 1021
Query: 180 FTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQH----EQQ 235
K + +Q++D L K +L K K L+ ++ Q+ E
Sbjct: 1022 ILTKAKTKLEQQVDDLEGSLEQE-----KKLRMDLERAKRK-LEGDLKLAQESTMDMEND 1075
Query: 236 KKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQE 295
K+ L+ ++ ++ N +S++E D + + I+EL+A++ + EE++ +
Sbjct: 1076 KQQLDEKLEKKEFEISNLISKIE----DEQAVEIQLQKKIKELQARIEELGEEIEAERAS 1131
Query: 296 VLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVL 355
++ S L E E + + + + Q+ L K + Q+ + L
Sbjct: 1132 RAKAEKQRSDLSRELEEISERLEEAGGATSA---------QVELNKKREAE-FQKLRRDL 1181
Query: 356 EENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLL 415
EE +++ + L AEL + + +++++ L+ +LK++ + +
Sbjct: 1182 EEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAI 1241
Query: 416 AEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLE----ESKQLLKNNEKLI 471
++ + L+K + L+D L+ KE+E +L L A +L+ E + L + L+
Sbjct: 1242 SKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALV 1301
Query: 472 TWLNK 476
+ L++
Sbjct: 1302 SQLSR 1306
Score = 50.4 bits (119), Expect = 5e-06
Identities = 52/254 (20%), Positives = 109/254 (42%), Gaps = 15/254 (5%)
Query: 209 KHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERK 268
K + + LQA+++ +Q + + +Q + R+ L N L K
Sbjct: 1671 KEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTK 1730
Query: 269 YKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLE 328
K ++ + +L++++ V +E + +++ + + + E +++ L+ LE
Sbjct: 1731 KKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLE 1790
Query: 329 QEIKD-------KDQLVLR-TKEAFDTIQEQKVVLE---ENGEKNQVQ----LGKLEATI 373
Q +KD +QL L+ K+ ++ + LE EN +K + L K E +
Sbjct: 1791 QTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRV 1850
Query: 374 KSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVG 433
K L+ + + + + +LQ + L K+K + E+ K +K Q EL++
Sbjct: 1851 KELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAE 1910
Query: 434 QSLRIKEQEVCKLQ 447
+ I E +V KL+
Sbjct: 1911 ERADIAESQVNKLR 1924
Score = 42.4 bits (98), Expect = 0.001
Identities = 52/227 (22%), Positives = 100/227 (44%), Gaps = 31/227 (13%)
Query: 255 SELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKE 314
+E E + E K + + +AK +EE++ ++L +E + L ++ +
Sbjct: 846 AETEKEMATMKEEFQKTKDELAKSEAKRKELEEKM-------VTLLKEKNDLQLQVQSEA 898
Query: 315 KHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIK 374
+ + + EQ IK+K QL + KE + +E++ + E K + KLE
Sbjct: 899 DSLADAEER---CEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKR----KLEDECS 951
Query: 375 SLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKL-LAEKEEKLQKEQKELQDVG 433
L ++ + K++ + K+K + +E L E KL KE+K LQ+
Sbjct: 952 ELKKDIDDLELTLAKVEKEKHATENKVK-----NLTEEMAGLDETIAKLSKEKKALQETH 1006
Query: 434 Q----SLRIKEQEV-------CKLQEQLEATVKKLEESKQLLKNNEK 469
Q L+ +E +V KL++Q++ LE+ K+L + E+
Sbjct: 1007 QQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLER 1053
Score = 40.8 bits (94), Expect = 0.004
Identities = 39/170 (22%), Positives = 85/170 (50%), Gaps = 9/170 (5%)
Query: 319 QLQTKVAVLEQEI-KDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLS 377
+ + ++A +++E K KD+L +++ ++E+ V L + EKN +QL ++S +
Sbjct: 847 ETEKEMATMKEEFQKTKDELA-KSEAKRKELEEKMVTLLK--EKNDLQL-----QVQSEA 898
Query: 378 AELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLR 437
L A E ++L + L K+K ++E++ AE K +K + E ++ + +
Sbjct: 899 DSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDID 958
Query: 438 IKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQ 487
E + K++++ AT K++ + + ++ I L+KE Q +Q
Sbjct: 959 DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQ 1008
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 78.2 bits (191), Expect = 2e-14
Identities = 85/392 (21%), Positives = 163/392 (41%), Gaps = 73/392 (18%)
Query: 161 KEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEK 220
++ + L + + ++L R++ AEK +++++ + E A+H A L + ELT +
Sbjct: 929 EDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEE-KCESAAHEADLKRQKVIELTGTARQ 987
Query: 221 ALQAQVQYQQQHEQQKKDLEILHQQN---------------IHQLQNRLSELEAANKDLT 265
QY++ E K + EI+H + + Q + L + A K+L
Sbjct: 988 VKIEMDQYKE--ELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELE 1045
Query: 266 ERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTL-------DVECHEKEKHVN 318
+ ++ ++ + E K +E ELQ E+ S R+ L + EK +
Sbjct: 1046 KLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIK 1105
Query: 319 QLQTKVAVLEQEIKDKDQLVLRTKEAF------------DTIQEQKVVLEENGEKNQVQL 366
L ++ + EI+DK Q +L +A + E GE Q ++
Sbjct: 1106 DLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQ-KI 1164
Query: 367 GKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEK------------- 413
KLE T++ EL + N+ I+ L L+ +L+ K + +Q E+
Sbjct: 1165 IKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQ 1224
Query: 414 --------LLAEKEEKLQKEQKELQDVGQSLRIKEQEV--------------CKLQEQLE 451
++ E+E+ + + KE D+GQ LR+ ++V + Q ++E
Sbjct: 1225 QRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIE 1284
Query: 452 ATVKKLEESKQLLKNNEKLITWLNKELNENQL 483
+LE+ KQL K + L +EL +++
Sbjct: 1285 RLSSELEDMKQLSKEKDAHGNHLAEELGASKV 1316
Score = 75.1 bits (183), Expect = 2e-13
Identities = 98/465 (21%), Positives = 205/465 (44%), Gaps = 85/465 (18%)
Query: 85 QKFIDLLQQ---CTQEHAKEIPRFLLQLVSPAAILDNSPAFLNVVETNPFKHLTHLSLKL 141
+K + +LQQ C Q H + + R L + + + N K +L+
Sbjct: 788 EKTMSMLQQDIICKQHHLESLDRLLTESKG------------EMKKENMKKDEALKALQN 835
Query: 142 LPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWAS 201
+ + L L+ KEE + + L+ ++ + K L +K +E+ L+ E
Sbjct: 836 QVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFE---KQLKKKSEEVYCLQKELK- 891
Query: 202 HTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQK-------KDLEILHQQNIHQLQNRL 254
HS + T+E+ LQ +Q QQQ QQ+ +D + ++ + +L+ L
Sbjct: 892 -----IKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQEL 946
Query: 255 S-ELEAANKDLTERKYKGDS-----------------TIRELKAKLSGVEEELQRTKQEV 296
+ E++ + L + + K +S T R++K ++ +EEL + ++E+
Sbjct: 947 QKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEI 1006
Query: 297 LSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTK-EAFDTIQEQKVVL 355
+ L+R+ + + + ++Q +T++ +K+ ++L T+ E + +Q+++V+
Sbjct: 1007 MHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLE 1066
Query: 356 EE----NGE----------------KNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLK 395
E +GE K Q+ L + TIK L+AEL + I+ + +L
Sbjct: 1067 TELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELL 1126
Query: 396 TLMGKLKLKN-------------TVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQE 442
+ LK +N +TI++ + E E+K+ K + L+ L+ ++
Sbjct: 1127 EMDQALKERNWELKQRAAQVTHLDMTIREHR--GEMEQKIIKLEGTLEKSELELKECNKQ 1184
Query: 443 VCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQ 487
+ L ++L+ ++L E + ++ NE+ I+ L KE+ Q K+
Sbjct: 1185 IESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKE 1229
Score = 67.4 bits (163), Expect = 4e-11
Identities = 79/356 (22%), Positives = 157/356 (44%), Gaps = 38/356 (10%)
Query: 156 CLKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAA---LTNKHSQ 212
C+ C + KL + + R LA K+ E+ KL ++ + +T SQ
Sbjct: 548 CIGCCEANKLVISE-----------LRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQ 596
Query: 213 ELTNEKEKALQAQ------------VQYQQQH---EQQKKDLEILHQQNIHQLQNRLSEL 257
E + K +L+ + V+ Q QH +Q +K+ + L I +L+ +L ++
Sbjct: 597 E--SSKLSSLETEPVKLGGHQVAESVKDQNQHTMNKQYEKERQRL-VTGIEELRTKLIQI 653
Query: 258 EAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHV 317
EA N DL S + ++ +L + + E+ + TL+ + EK
Sbjct: 654 EAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAY 713
Query: 318 NQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGK-LEATIKSL 376
+ + K A LEQE+ +K++ + + +T E+ + E +K ++ K +E I+ L
Sbjct: 714 SSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERL 773
Query: 377 SAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSL 436
A+L K ++ K+ + + L + K ++LL E + +++KE + + ++L
Sbjct: 774 EAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKAL 833
Query: 437 RIKEQEVCKLQEQLEATVKKLEES-----KQLLKNNEKLITWLNKELNENQLVRKQ 487
+ + E QL++ ++ +E QL N EK L K+ E ++K+
Sbjct: 834 QNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKE 889
Score = 59.3 bits (142), Expect = 1e-08
Identities = 68/291 (23%), Positives = 132/291 (45%), Gaps = 24/291 (8%)
Query: 171 LDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTN--KHSQELTNEKEKALQAQVQY 228
L +A +L+ ++K + EK+Q L + + E L K + ++ +AL +
Sbjct: 307 LREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAEEL 366
Query: 229 QQQHEQQKKDL-EILHQQNIHQ--LQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGV 285
+ +Q KK + E L + + L+ L+ E NK L ER S + LK KL +
Sbjct: 367 SKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQL 426
Query: 286 EEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAF 345
+EE K+++ + +NS + + E + + LE E+++KD+++ ++ F
Sbjct: 427 KEENNNGKEKLRIMAVKNSEVMAQLTESRQ-------SILKLESELENKDEIL---RDKF 476
Query: 346 DTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKN 405
+ E + + +N+ +L + I+S EL +II +L + L G K+
Sbjct: 477 SLMNENRELKVRVAAQNE-RLDLCQQEIESSRVELRSLEKIISQLPLK-RELFG---FKS 531
Query: 406 TVTIQQEKLLAEKEEK----LQKEQKELQDVGQSLRIKEQEVCKLQEQLEA 452
++ Q + KE++ + + + ++ L IKE E+ KL L A
Sbjct: 532 YLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTA 582
Score = 59.3 bits (142), Expect = 1e-08
Identities = 76/327 (23%), Positives = 151/327 (46%), Gaps = 40/327 (12%)
Query: 163 EKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKE--- 219
E L ++ T Q ++ L EK KL +E +T K SQ LT EK+
Sbjct: 656 ENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESE-------MTKKCSQLLTLEKQLEE 708
Query: 220 -----KALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLS-ELEAANKDLTERKYKGDS 273
++ A+ +Q +K + + NI+ ++ E A K E+ + +
Sbjct: 709 KIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEK 768
Query: 274 TIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKD 333
I L+A+L +++ + ++ + L++ D+ C K+ H+ L + + E+K
Sbjct: 769 QIERLEAQLEKKDQQFKEQEKTMSMLQQ-----DIIC--KQHHLESLDRLLTESKGEMKK 821
Query: 334 ----KDQLV--LRTKEAFDTIQEQKV--VLEENGEKNQVQLGKLEATIKSLSAELLKANE 385
KD+ + L+ + + +TI+ +++ LE E+ + L +LE + +L K +E
Sbjct: 822 ENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSE 881
Query: 386 IIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKE---QKELQDVGQSLRIKEQE 442
+ LQ +LK L+ + + + L ++++ LQ+E EL+D L E++
Sbjct: 882 EVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKL---EKQ 938
Query: 443 VCKLQEQLEATVKKLEESKQLLKNNEK 469
V KL+++L+ K+ E S + L+ E+
Sbjct: 939 VSKLEQELQ---KQRESSAEKLRKMEE 962
Score = 57.4 bits (137), Expect = 4e-08
Identities = 82/393 (20%), Positives = 165/393 (41%), Gaps = 44/393 (11%)
Query: 125 VVETNPFKHLTHLSLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFTRKT 184
V E +H T L ++ ++ L L+ + E S ++ L + L + +
Sbjct: 1041 VKELEKLQHSTETELT----EALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLS 1096
Query: 185 LAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQ 244
L EK + L E + +K + L E ++AL+ + +Q Q L++ +
Sbjct: 1097 LEEKYTTIKDLTAELRECKMEIEDKKQELL--EMDQALKERNWELKQRAAQVTHLDMTIR 1154
Query: 245 QNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENS 304
++ +++ ++ +LE + + + I L KL +E+L+ ++E + L+ E
Sbjct: 1155 EHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLR--EKEFIMLQNEQ- 1211
Query: 305 TLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVL-RTKEAFDTIQEQKVVLEE------ 357
E + +K + + Q ++ +E +K+++Q + + KEA D QE ++ E+
Sbjct: 1212 ----EISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHT 1267
Query: 358 ---NGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKL 414
QVQ + I+ LS+EL ++ K+ L +L E
Sbjct: 1268 ELAEARHQQVQA---QREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEAR 1324
Query: 415 LAEKEEKLQKEQKELQDVGQSLRIKEQE---------------VCKLQEQLEATVKKLEE 459
+ + +KL E + L++ I QE V +L EQLE +LEE
Sbjct: 1325 MQAEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEE 1384
Query: 460 SKQLLKNNEKLITWLNKEL---NENQLVRKQDV 489
++ + N + + N+ + NE L + ++V
Sbjct: 1385 AQDTVSNLHQQVQDRNEVIEAANEALLTKGENV 1417
Score = 50.8 bits (120), Expect = 4e-06
Identities = 78/369 (21%), Positives = 153/369 (41%), Gaps = 71/369 (19%)
Query: 111 SPAAILDNSPAFLNVVETNPFKHLTHLSLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQS 170
S ILD P+ ++ +P++++ +S G+ + +K +++ S
Sbjct: 179 SEKLILDVQPSHPGLLNYSPYENVCKIS-----GSSTDFQKK-------PRDKMFSSSAP 226
Query: 171 LDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQ---------ELTNEKEKA 221
+D K L +++L+KLR + + +T HS ELT +
Sbjct: 227 VDQEIKSL----------REKLNKLRQQ---NACLVTQNHSLMTKFESIHFELTQSR--- 270
Query: 222 LQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAK 281
A+V + +QQ + IL +Q I N +E+ A +K L E + K + + + + K
Sbjct: 271 --AKVSMLESAQQQAASVPILEEQII----NLEAEVSAQDKVLREAENKLEQSQKMVIEK 324
Query: 282 LSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRT 341
E+ LQ +K+E + L+ V+ E+ K + + + +++ +
Sbjct: 325 ----EQSLQESKEECIKLK-------VDLLEQTKQGKRAE----------RQRNEALYNA 363
Query: 342 KEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKL 401
+E Q+ K + E EK Q + LE + + E + E + +L+ L KL
Sbjct: 364 EELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKL 423
Query: 402 KLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESK 461
+ Q ++ +EKL+ + +V L Q + KL+ +LE + L +
Sbjct: 424 R-------QLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILRDKF 476
Query: 462 QLLKNNEKL 470
L+ N +L
Sbjct: 477 SLMNENREL 485
Score = 42.0 bits (97), Expect = 0.002
Identities = 58/256 (22%), Positives = 111/256 (43%), Gaps = 35/256 (13%)
Query: 245 QNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENS 304
Q I L+ +L++L N L + + L K + EL +++ +V L
Sbjct: 229 QEIKSLREKLNKLRQQNACLVTQNHS-------LMTKFESIHFELTQSRAKVSMLE---- 277
Query: 305 TLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQV 364
++ V L+ ++ LE E+ +D+++ + + Q QK+V+E K Q
Sbjct: 278 ----SAQQQAASVPILEEQIINLEAEVSAQDKVLREAENKLE--QSQKMVIE----KEQS 327
Query: 365 QLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQK 424
E IK L +LL+ + K+ + + + + Q +K +AEK L+K
Sbjct: 328 LQESKEECIK-LKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEK---LEK 383
Query: 425 EQKELQDVGQSLRIKEQEVCKLQE-------QLEATVKKLEESKQLLKNNE---KLITWL 474
Q E + + ++L E+E +LQE +LE +KL + K+ N + +++
Sbjct: 384 VQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKLRIMAVK 443
Query: 475 NKELNENQLVRKQDVL 490
N E+ +Q +L
Sbjct: 444 NSEVMAQLTESRQSIL 459
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 77.0 bits (188), Expect = 5e-14
Identities = 75/364 (20%), Positives = 172/364 (47%), Gaps = 44/364 (12%)
Query: 157 LKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQ--ELDKLRNEWASHTAALTN------ 208
L+ + EK + ++ D ++L+ + L +++ E D+L E S +A L
Sbjct: 227 LRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENE 286
Query: 209 --------------KHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQN-------- 246
+ +++ ++EK + +++ ++Q E+ + E +H+Q
Sbjct: 287 LWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQED 346
Query: 247 -IHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENST 305
+ + + ++ E E ++ E+ ++ + IRE K+ EEE+ R ++++ R +
Sbjct: 347 KMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKI---REQEEK 403
Query: 306 LDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQ 365
+ +EK + + K+ E+E+ +++ + +E + +Q+Q+ L E EK Q +
Sbjct: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI---RELEEMMQDQEEKLREVEEKMQEE 460
Query: 366 LGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKL--KNTVTIQQEKLLAEKEEKLQ 423
K++ + + + K E +K K L + K+ + +QE+ + E+EEK+Q
Sbjct: 461 EEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQ 520
Query: 424 KEQKELQDVGQSLRIKE----QEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELN 479
++++++Q + +R +E Q+ K+QEQ E +++LEE L +L+ +E
Sbjct: 521 EQEEKMQRQEEKMREQEVRLWQQEEKMQEQ-EVRLQELEERLGKLGQKAELLGGAGRESG 579
Query: 480 ENQL 483
+L
Sbjct: 580 SQRL 583
Score = 75.9 bits (185), Expect = 1e-13
Identities = 70/316 (22%), Positives = 162/316 (51%), Gaps = 12/316 (3%)
Query: 181 TRKTLAEKKQEL-DKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDL 239
T + L EK EL +KLR + + N + E+ + L Q Q Q + ++ K+L
Sbjct: 212 TDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKEL 271
Query: 240 EILHQQNIHQLQ-NRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLS 298
+ + + Q++ N L L N+ E+ ++ + I+E + K+ E+EL+ +QE
Sbjct: 272 QSVSAKLQAQVEENELWNL--LNQQQEEKMWRQEEKIQEQEEKMC--EQELKIREQEEKM 327
Query: 299 LRRENSTLDVE--CHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAF----DTIQEQK 352
R+E + E E+E + + + K+ E++I+++++ + R +E + IQEQ+
Sbjct: 328 WRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE 387
Query: 353 VVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQE 412
+ EK + Q K + + ++ + +E I++ + ++ K++ + QE
Sbjct: 388 EEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQE 447
Query: 413 KLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLIT 472
+ L E EEK+Q+E++++Q+ + ++ +E+++ + +E+ K L++ +++ + EK+
Sbjct: 448 EKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWR 507
Query: 473 WLNKELNENQLVRKQD 488
K + + +++Q+
Sbjct: 508 QEEKMWEQEEKMQEQE 523
Score = 53.9 bits (128), Expect = 5e-07
Identities = 52/261 (19%), Positives = 122/261 (46%), Gaps = 22/261 (8%)
Query: 238 DLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVL 297
D E + + ++ E++++ K E+ + + T R K +++ R +
Sbjct: 112 DDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFR----KRVVIKKPWLRLGEVTA 167
Query: 298 SLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEE 357
R ENS L+ H H ++ T + L +E + R + ++E+ L+E
Sbjct: 168 QKRPENSLLEETLHFD--HAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQE 225
Query: 358 N-----GEKNQVQLGKLEATIKSLSAELLKANEIIK----KLQGDLKTLMGKLK------ 402
EK+++QL + K A+LL + ++ +L +L+++ KL+
Sbjct: 226 KLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEEN 285
Query: 403 -LKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESK 461
L N + QQE+ + +EEK+Q++++++ + +R +E+++ + +E++ +K+ E +
Sbjct: 286 ELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQE 345
Query: 462 QLLKNNEKLITWLNKELNENQ 482
+ E+ I +++ E +
Sbjct: 346 DKMWRQEEKIREQEEKIREQE 366
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 77.0 bits (188), Expect = 5e-14
Identities = 75/364 (20%), Positives = 172/364 (47%), Gaps = 44/364 (12%)
Query: 157 LKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQ--ELDKLRNEWASHTAALTN------ 208
L+ + EK + ++ D ++L+ + L +++ E D+L E S +A L
Sbjct: 227 LRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENE 286
Query: 209 --------------KHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQN-------- 246
+ +++ ++EK + +++ ++Q E+ + E +H+Q
Sbjct: 287 LWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQED 346
Query: 247 -IHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENST 305
+ + + ++ E E ++ E+ ++ + IRE K+ EEE+ R ++++ R +
Sbjct: 347 KMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKI---REQEEK 403
Query: 306 LDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQ 365
+ +EK + + K+ E+E+ +++ + +E + +Q+Q+ L E EK Q +
Sbjct: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI---RELEEMMQDQEEKLREVEEKMQEE 460
Query: 366 LGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKL--KNTVTIQQEKLLAEKEEKLQ 423
K++ + + + K E +K K L + K+ + +QE+ + E+EEK+Q
Sbjct: 461 EEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQ 520
Query: 424 KEQKELQDVGQSLRIKE----QEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELN 479
++++++Q + +R +E Q+ K+QEQ E +++LEE L +L+ +E
Sbjct: 521 EQEEKMQRQEEKMREQEVRLWQQEEKMQEQ-EVRLQELEERLGKLGQKAELLGGAGRESG 579
Query: 480 ENQL 483
+L
Sbjct: 580 SQRL 583
Score = 75.9 bits (185), Expect = 1e-13
Identities = 70/316 (22%), Positives = 162/316 (51%), Gaps = 12/316 (3%)
Query: 181 TRKTLAEKKQEL-DKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDL 239
T + L EK EL +KLR + + N + E+ + L Q Q Q + ++ K+L
Sbjct: 212 TDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKEL 271
Query: 240 EILHQQNIHQLQ-NRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLS 298
+ + + Q++ N L L N+ E+ ++ + I+E + K+ E+EL+ +QE
Sbjct: 272 QSVSAKLQAQVEENELWNL--LNQQQEEKMWRQEEKIQEQEEKMC--EQELKIREQEEKM 327
Query: 299 LRRENSTLDVE--CHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAF----DTIQEQK 352
R+E + E E+E + + + K+ E++I+++++ + R +E + IQEQ+
Sbjct: 328 WRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE 387
Query: 353 VVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQE 412
+ EK + Q K + + ++ + +E I++ + ++ K++ + QE
Sbjct: 388 EEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQE 447
Query: 413 KLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLIT 472
+ L E EEK+Q+E++++Q+ + ++ +E+++ + +E+ K L++ +++ + EK+
Sbjct: 448 EKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWR 507
Query: 473 WLNKELNENQLVRKQD 488
K + + +++Q+
Sbjct: 508 QEEKMWEQEEKMQEQE 523
Score = 54.3 bits (129), Expect = 3e-07
Identities = 54/264 (20%), Positives = 124/264 (46%), Gaps = 28/264 (10%)
Query: 238 DLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVL 297
D E + + ++ E++++ K E+ + + T R K +++ R +
Sbjct: 112 DDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFR----KRVVIKKPWLRLGEVTA 167
Query: 298 SLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVL---RTKEAFDTIQEQKVV 354
R ENS L E+ H + +E+ K++D L L R + ++E+
Sbjct: 168 QKRPENSLL-----EETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAE 222
Query: 355 LEEN-----GEKNQVQLGKLEATIKSLSAELLKANEIIK----KLQGDLKTLMGKLK--- 402
L+E EK+++QL + K A+LL + ++ +L +L+++ KL+
Sbjct: 223 LQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQV 282
Query: 403 ----LKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLE 458
L N + QQE+ + +EEK+Q++++++ + +R +E+++ + +E++ +K+
Sbjct: 283 EENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIR 342
Query: 459 ESKQLLKNNEKLITWLNKELNENQ 482
E + + E+ I +++ E +
Sbjct: 343 EQEDKMWRQEEKIREQEEKIREQE 366
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 77.0 bits (188), Expect = 5e-14
Identities = 86/346 (24%), Positives = 158/346 (45%), Gaps = 48/346 (13%)
Query: 170 SLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQ 229
SL +L + + L EK +E+ + NE L N+ S T E+EK L + Q
Sbjct: 860 SLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQ 919
Query: 230 QQHE-----QQKKDLEILHQQ----------NIHQLQNRLSELEAANKDLTERKYKGDST 274
E Q+K DL+ L + +IH N + + ++ E + T
Sbjct: 920 TLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQET 979
Query: 275 IRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDK 334
I LK+K+S EE+ R +L E +T + + ++K V + + + E K+
Sbjct: 980 INTLKSKIS---EEVSR------NLHMEENTGETKDEFQQKMVGIDKKQ----DLEAKNT 1026
Query: 335 DQLVLRTKEAFDTIQEQKVVLEENGEKNQVQ--LGKLEATIKSLSAELLKANEIIKKLQG 392
L K+ + I++Q+ + EKN++Q L + A + L +L + E+ + Q
Sbjct: 1027 QTLTADVKDN-EIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQE 1085
Query: 393 DLKTLMGKLKLKNTVTIQQEKLLAEKE-------EKLQKEQKELQDVGQSLRIKEQEVCK 445
+L+ L +LK + + Q++ +KE ++L + +++L++ Q L+ K+Q++
Sbjct: 1086 ELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLN 1145
Query: 446 LQEQLEATVKKLEESKQL---LKNNEKLITWLNKE-------LNEN 481
+QE++ KK+ E + L LKN E + + E LNEN
Sbjct: 1146 VQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNEN 1191
Score = 72.0 bits (175), Expect = 2e-12
Identities = 82/347 (23%), Positives = 162/347 (46%), Gaps = 27/347 (7%)
Query: 148 EIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELD---KLRNEWASHTA 204
E+K+F K ++ K S +QS++ +K L+ T + L E ++E+ K + E
Sbjct: 1549 ELKQF-----KEHRKAKDSALQSIE--SKMLELTNR-LQESQEEIQIMIKEKEEMKRVQE 1600
Query: 205 ALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDL 264
AL + Q N KE + + E Q+K+ + L +++ Q ++ E+E +
Sbjct: 1601 ALQIERDQLKENTKEIVAKMK-------ESQEKEYQFLKMTAVNETQEKMCEIEHLKEQF 1653
Query: 265 TERKYKGDSTIRE---LKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQ 321
+K ++ E L L EE++ +E LR TL VE + ++++ +
Sbjct: 1654 ETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETI 1713
Query: 322 TKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELL 381
T+ ++E+K + + KE +TI + + ++ E + LE + +L A+ L
Sbjct: 1714 TRDLEKQEELKI---VHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDL 1770
Query: 382 KANEIIKKLQGDLKTLMGKL-KLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKE 440
K E ++ LK + KL+ V+ + +KL + ++ L+ +LQ+ Q L+ E
Sbjct: 1771 KIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKL-SNMQKDLENSNAKLQEKIQELKANE 1829
Query: 441 QEVCKLQEQLEATVKKLEESKQLLKN-NEKLITWLNKELNENQLVRK 486
++ L++ + T KK+ E +QL K ++ +T E+ L +K
Sbjct: 1830 HQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQK 1876
Score = 71.6 bits (174), Expect = 2e-12
Identities = 76/369 (20%), Positives = 166/369 (44%), Gaps = 49/369 (13%)
Query: 163 EKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHS------QELTN 216
E++ L+ L +++ RK + +K +EL + +E + + +K S +E+
Sbjct: 741 EEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGK 800
Query: 217 EKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKD---LTERKYKGDS 273
K+ Q Y+ +Q+ ++ + LH + + L E E N++ L++ K DS
Sbjct: 801 TKDDLATTQSNYKST-DQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDS 859
Query: 274 TIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKD 333
++ LK +LS +ELQ +EV E L + ++ + ++ + ++ ++++
Sbjct: 860 SLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQ- 918
Query: 334 KDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIK-------SLSAELLKANEI 386
+T E T+ ++K L++ E Q++ +L++ I +L A E
Sbjct: 919 ------QTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALES 972
Query: 387 IKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQK-----------EQKELQDVGQS 435
+K+ Q + TL K+ + + + E+ E +++ Q+ E K Q +
Sbjct: 973 LKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTAD 1032
Query: 436 LRIKE------------QEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELN--EN 481
++ E QE +LQ+ LE+ + + E+ K LK N ++ +EL +
Sbjct: 1033 VKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGD 1092
Query: 482 QLVRKQDVL 490
+L ++Q+++
Sbjct: 1093 ELKKQQEIV 1101
Score = 69.3 bits (168), Expect = 1e-11
Identities = 80/333 (24%), Positives = 158/333 (47%), Gaps = 46/333 (13%)
Query: 176 KQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQ 235
++L L E ++ +D+LR + TA + N E ++ K Q + HE+Q
Sbjct: 1235 EELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTK-----LQEEIPVLHEEQ 1289
Query: 236 KKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQE 295
+ + + + + + Q ++ELE + T K +T+ ++ + + E+ Q +++E
Sbjct: 1290 EL---LPNVKEVSETQETMNELELLTEQSTT---KDSTTLARIEMERLRLNEKFQESQEE 1343
Query: 296 VLSLRRENSTL-------DVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTI 348
+ SL +E L +V+ + ++H+ + K+ QE + K + L KE +
Sbjct: 1344 IKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKI----QESQSKQEQSLNMKEKDN-- 1397
Query: 349 QEQKVVLE-ENGEKNQVQLGKLEATIKSLSAELLKANEIIK----------KLQGDLKTL 397
+ K+V E E + L ++E + LS L ++++ +K +LQ L++
Sbjct: 1398 ETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSE 1457
Query: 398 MGKLKLKNTVTIQQEKLLAEKEEKLQ----KEQKE-LQDVGQSLRIKEQEVCKLQEQLEA 452
+LK +N I + L E+E K+ KEQ+E + ++ +L KE E+ +Q+QLEA
Sbjct: 1458 SDQLK-ENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEA 1516
Query: 453 TVKKLEESKQLLKNNE-----KLITWLNKELNE 480
KL+ Q + E K I+ + +++NE
Sbjct: 1517 INDKLQNKIQEIYEKEEQFNIKQISEVQEKVNE 1549
Score = 69.3 bits (168), Expect = 1e-11
Identities = 72/323 (22%), Positives = 162/323 (50%), Gaps = 32/323 (9%)
Query: 176 KQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQ 235
++L L E+++ +DKLR + T L+N ++L N K LQ ++Q + +E Q
Sbjct: 1774 EELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQ-KDLENSNAK-LQEKIQELKANEHQ 1831
Query: 236 KKDLEILHQQNIHQLQNRLSELEAANKDLTERKY---KGDSTIRELKAKLSGVEEELQRT 292
L+ +++++ Q ++SE+E K + ++ K + L KL EE++
Sbjct: 1832 LITLK----KDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSV 1887
Query: 293 KQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQE-- 350
+E +LRR TL +E + ++ + + + + ++QE+K L KE D ++E
Sbjct: 1888 MKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKI 1947
Query: 351 -QKVV----LEENGEKNQVQLGKLEATIKSLSAELLKANEIIK---KLQGDLKTLMGKLK 402
+K + ++++ +K++ +L K ++ +LL+ E + K +++ L + +
Sbjct: 1948 SEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFE 2007
Query: 403 LKN----TVTIQQEKLLAEKEEKLQ------KEQKELQDVGQSLRI-KEQEVCKLQEQL- 450
+N +V + +L + E L+ KE+ EL+ + +SL++ ++Q + L+E +
Sbjct: 2008 AQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIA 2067
Query: 451 -EATVKKLEESKQLLKNNEKLIT 472
+ +++ K+LL + ++ +T
Sbjct: 2068 RDRQNHQVKPEKRLLSDGQQHLT 2090
Score = 63.2 bits (152), Expect = 8e-10
Identities = 74/366 (20%), Positives = 162/366 (44%), Gaps = 53/366 (14%)
Query: 157 LKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTN 216
LK E++S +++ T + T+ +K +DK ++ A +T LT
Sbjct: 983 LKSKISEEVSRNLHMEENTGE---TKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEII 1039
Query: 217 EKEKALQAQVQYQQQHEQ-------QKKDLEILHQQNIHQLQNRLSELEAANKDLTER-- 267
E+++ + + +Q + + +Q +K+ L+ ++NI EL +L ++
Sbjct: 1040 EQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQE 1099
Query: 268 ----------KYKGDST-----IRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHE 312
K +G+ + + E++ KL ++LQ +Q++L+++ E S + + +E
Sbjct: 1100 IVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINE 1159
Query: 313 KEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFD---TIQEQKVVLEENGEKNQVQLGKL 369
E N+L+ K LE ++ +L + E ++ +I +++ VL+E + + + L
Sbjct: 1160 IENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHL 1219
Query: 370 EATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKEL 429
I+ + A L+ E +K LK E +E + + ++ +
Sbjct: 1220 RGYIREIEATGLQTKEELKIAHIHLK---------------------EHQETIDELRRSV 1258
Query: 430 QDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQDV 489
+ + I Q++ K +L+ + L E ++LL N K ++ + +NE +L+ +Q
Sbjct: 1259 SEKTAQI-INTQDLEKSHTKLQEEIPVLHEEQELLP-NVKEVSETQETMNELELLTEQST 1316
Query: 490 LGPSTT 495
STT
Sbjct: 1317 TKDSTT 1322
Score = 62.4 bits (150), Expect = 1e-09
Identities = 73/326 (22%), Positives = 151/326 (46%), Gaps = 55/326 (16%)
Query: 176 KQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQ-ELTNEKEKALQAQVQYQQQHEQ 234
++L L E ++ +DKLR + T ++N E +N+ KA ++Q
Sbjct: 1721 EELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQ------- 1773
Query: 235 QKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQ 294
++L I H ++ + Q + +L + T++ + AKL +EL+ +
Sbjct: 1774 --EELRIAHM-HLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEH 1830
Query: 295 EVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKD-KDQLVLRTK----------E 343
++++L+++ VN+ Q KV+ +EQ K KDQ + +K +
Sbjct: 1831 QLITLKKD--------------VNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQK 1876
Query: 344 AFDTIQEQKVVLEENGEKNQVQLG-KLEATIKSLSAELLKANEIIKKLQGDLKTL-MGKL 401
+ ++E K V++E +V+ KLE S + KA ++ ++Q +LKT M
Sbjct: 1877 LHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDL--EIQQELKTARMLSK 1934
Query: 402 KLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESK 461
+ K TV +EK+ +EK ++ QK+L K +++L+ +++L++ +
Sbjct: 1935 EHKETVDKLREKI-SEKTIQISDIQKDLD--------------KSKDELQKKIQELQKKE 1979
Query: 462 QLLKNNEKLITWLNKELNENQLVRKQ 487
L ++ + +K++NE + ++KQ
Sbjct: 1980 LQLLRVKEDVNMSHKKINEMEQLKKQ 2005
Score = 53.5 bits (127), Expect = 6e-07
Identities = 72/311 (23%), Positives = 141/311 (45%), Gaps = 33/311 (10%)
Query: 160 SKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKE 219
S+EE SL + D+ L ++ L K +L + E + +K Q L N KE
Sbjct: 1340 SQEEIKSLTKERDN----LKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSL-NMKE 1394
Query: 220 KALQAQVQYQQQHEQQKKDLEILHQQ-NIHQLQNRLSELEAANKDLTERKYKGDSTIREL 278
K + + + + KD +L + + L RL E K + + K ++ L
Sbjct: 1395 KDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEK----DDLQRL 1450
Query: 279 KAKLSGVEEELQRTKQEVLS--LRRENSTLDVEC--HEKEKHVNQLQTKVAVLEQEIKDK 334
+ L ++L+ +E+++ L E C E+E+ +N+L+ ++ E EI
Sbjct: 1451 QEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEI--- 1507
Query: 335 DQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDL 394
+ + EA + + K+ +E EK + + IK +S K NE +K+ +
Sbjct: 1508 -STIQKQLEAINDKLQNKI--QEIYEKEE------QFNIKQISEVQEKVNE-LKQFKEHR 1557
Query: 395 KTLMGKLKLKNTVTIQQEKLLAEKEEKLQ---KEQKELQDVGQSLRIKEQEVCKLQEQLE 451
K L+ + ++ L E +E++Q KE++E++ V ++L+I+ + L+E +
Sbjct: 1558 KAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQ---LKENTK 1614
Query: 452 ATVKKLEESKQ 462
V K++ES++
Sbjct: 1615 EIVAKMKESQE 1625
Score = 51.2 bits (121), Expect = 3e-06
Identities = 100/403 (24%), Positives = 170/403 (42%), Gaps = 90/403 (22%)
Query: 139 LKLLPGNDVEIKKFLAGCLKCSKEEKLSL-----MQSLDDAT--KQLDFTRKTLA-EKKQ 190
++LL + +IKK L + K E + + ++S++D KQ F +T+A + K+
Sbjct: 581 VELLREKEDQIKK-LQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKR 639
Query: 191 ELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKK---DLEILHQQNI 247
E LR+E L K + T K+ Q+ YQ Q E +KK DLE Q
Sbjct: 640 ESAFLRSE----NLELKEKMKELATTYKQMENDIQL-YQSQLEAKKKMQVDLEKELQSAF 694
Query: 248 HQ---------------------LQNRLSELEAA-NKDLTERKYKGDSTI--RELKAKLS 283
++ L+ ++++L+ NK++ E + + I ELK+ S
Sbjct: 695 NEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPS 754
Query: 284 GVE---EELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLR 340
VE +E+Q +E+ + E L E KE V L ++ + ++
Sbjct: 755 EVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKS 814
Query: 341 TKEAF--------DTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQG 392
T + F D Q+ K+VLEEN NQ E++ ++ +K
Sbjct: 815 TDQEFQNFKTLHMDFEQKYKMVLEENERMNQ---------------EIVNLSKEAQKFDS 859
Query: 393 DLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQ-------SLRIKEQEVCK 445
L L +L K QE L EK ++Q+ E++ + + +L+ E+E
Sbjct: 860 SLGALKTELSYKT-----QE--LQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTL 912
Query: 446 LQEQLEATVKKLEESKQLLKNNEKLITWLNKELNEN-QLVRKQ 487
+ E+L+ T LEE K L + + L K+L E+ Q+ R Q
Sbjct: 913 ITEKLQQT---LEEVKTLTQEKDDL-----KQLQESLQIERDQ 947
Score = 47.8 bits (112), Expect = 3e-05
Identities = 72/320 (22%), Positives = 136/320 (42%), Gaps = 45/320 (14%)
Query: 189 KQELDKLRNEWAS----HTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQ 244
+ EL+ LR ++ + + T K EL +++ L +++ + KKD E+
Sbjct: 497 ESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLD---EFEALERKTKKDQEMQLI 553
Query: 245 QNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENS 304
I L+N + E N+DL +RE + ++ ++E + K E + + +
Sbjct: 554 HEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKM---DL 610
Query: 305 TLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTK--EAFDTIQEQKVVLEENGEKN 362
+ +E E K + Q + + K ++ LR++ E + ++E ++
Sbjct: 611 SYSLESIEDPKQMKQTLFDAETVALDAK-RESAFLRSENLELKEKMKELATTYKQMENDI 669
Query: 363 QVQLGKLEATIK---SLSAELLKANEIIKKLQGDL-----KTLMGKLKLKNTVTIQQEKL 414
Q+ +LEA K L EL A I KL + K L+ L+L+ +T Q++L
Sbjct: 670 QLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKEL 729
Query: 415 LAEKEE-------------------KLQKEQKELQDVGQSLRIKEQEVCKLQEQL---EA 452
E EE ++++ +KE+QD + L I E KL ++ E+
Sbjct: 730 NKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKES 789
Query: 453 TVKKLEESKQLLKNNEKLIT 472
V+ L E ++ K + L T
Sbjct: 790 RVQGLLE--EIGKTKDDLAT 807
Score = 47.4 bits (111), Expect = 4e-05
Identities = 61/296 (20%), Positives = 131/296 (44%), Gaps = 36/296 (12%)
Query: 198 EWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSEL 257
EW T L ++ + N V +Q +K+++E+ ++ +N L E
Sbjct: 483 EWNPATKLLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKE-----KNDLDEF 537
Query: 258 EAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHV 317
EA ERK K D + +L ++S ++ ++ + L E S+ EKE +
Sbjct: 538 EAL-----ERKTKKDQEM-QLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQI 591
Query: 318 NQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQL-GKLEATIKSL 376
+LQ + + + + + + + ++I++ K + + + V L K E+ L
Sbjct: 592 KKLQEYI-----DSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAF--L 644
Query: 377 SAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSL 436
+E L+ E +K+L K + ++L + ++K+ + E++LQ E+ + +
Sbjct: 645 RSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLI 704
Query: 437 --RIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQDVL 490
++ + +C L+ LE + L++ LNKE+ EN+ +R++ +L
Sbjct: 705 DGKVPKDLLCNLE--LEGKITDLQKE-------------LNKEVEENEALREEVIL 745
Score = 45.4 bits (106), Expect = 2e-04
Identities = 62/292 (21%), Positives = 120/292 (41%), Gaps = 36/292 (12%)
Query: 198 EWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSEL 257
E+ +A ++ + Q+L + KEK + YQ K L Q N N+ +
Sbjct: 2316 EFEERSATISKEWEQDLKSLKEKNEKLFKNYQTL----KTSLASGAQVNPTTQDNKNPHV 2371
Query: 258 EAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENST-------LDVEC 310
+ LT K IREL+ L +E + +++ +++E L +
Sbjct: 2372 TSRATQLTTEK------IRELENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKV 2425
Query: 311 HEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLE 370
HE K + + + + VL+ D++ L K + I++ K+ L + + + E
Sbjct: 2426 HESNKCLEKTKETIQVLQ------DKVALGAKPYKEEIEDLKMKLVKIDLEKMKNAKEFE 2479
Query: 371 ATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQ 430
I + A + E+I+ L+ +L+ + Q +++E + Q K L
Sbjct: 2480 KEISATKATVEYQKEVIRLLRENLR---------RSQQAQDTSVISEHTDP-QPSNKPLT 2529
Query: 431 DVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQ 482
G S ++ + L+ + K++ + KQ NE+LI N+ L+ NQ
Sbjct: 2530 CGGGSGIVQNTKALILKSEHIRLEKEISKLKQ---QNEQLIKQKNELLSNNQ 2578
Score = 42.4 bits (98), Expect = 0.001
Identities = 57/270 (21%), Positives = 118/270 (43%), Gaps = 28/270 (10%)
Query: 201 SHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAA 260
S LT + +EL N +A ++ + + + + +K+LE+ + I +LQ ++ E +
Sbjct: 2373 SRATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKELEVTNDI-IAKLQAKVHE---S 2428
Query: 261 NKDLTERKYKGDSTIRELKAKLS----GVEEELQRTKQEVLSLRRENSTLDVECHEKEKH 316
NK L + K TI+ L+ K++ +EE++ K +++ + E E EK
Sbjct: 2429 NKCLEKTK----ETIQVLQDKVALGAKPYKEEIEDLKMKLVKIDLEKMK---NAKEFEKE 2481
Query: 317 VNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEK---NQVQLGKLEATI 373
++ + V ++ I+ + + R+++A DT V+ E + + G +
Sbjct: 2482 ISATKATVEYQKEVIRLLRENLRRSQQAQDT----SVISEHTDPQPSNKPLTCGGGSGIV 2537
Query: 374 KSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVG 433
++ A +LK+ I L+ + KLK +N I+Q+ L + L E K ++
Sbjct: 2538 QNTKALILKSEHI------RLEKEISKLKQQNEQLIKQKNELLSNNQHLSNEVKTWKERT 2591
Query: 434 QSLRIKEQEVCKLQEQLEATVKKLEESKQL 463
+Q C+ + + KQ+
Sbjct: 2592 LKREAHKQVTCENSPKSPKVTGTASKKKQI 2621
Score = 41.6 bits (96), Expect = 0.002
Identities = 62/284 (21%), Positives = 121/284 (42%), Gaps = 42/284 (14%)
Query: 208 NKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTER 267
NK + +E EK Q ++ + QH QQ D+ +++ QN +E KD +E
Sbjct: 2192 NKFEMDFIDEVEK--QKELLIKIQHLQQDCDVPSRELRDLKLNQNMDLHIEEILKDFSES 2249
Query: 268 KYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTK---- 323
++ T E + LS +E+ + +E L+ R + L ++ + Q+
Sbjct: 2250 EFPSIKT--EFQQVLSN-RKEMTQFLEEWLNTRFDIEKLKNGIQKENDRICQVNNFFNNR 2306
Query: 324 -VAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLK 382
+A++ + + +++ +KE ++ K EKN+ KL ++L L
Sbjct: 2307 IIAIMNESTEFEERSATISKEWEQDLKSLK-------EKNE----KLFKNYQTLKTSLAS 2355
Query: 383 ANEIIKKLQGDLKTLMGKLKLKNT-VTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQ 441
++ Q + KN VT + +L EK +L+ L + +S KE
Sbjct: 2356 GAQVNPTTQDN----------KNPHVTSRATQLTTEKIRELENS---LHEAKESAMHKES 2402
Query: 442 EVCKLQEQLEAT-------VKKLEESKQLLKNNEKLITWLNKEL 478
++ K+Q++LE T K+ ES + L+ ++ I L ++
Sbjct: 2403 KIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKV 2446
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 77.0 bits (188), Expect = 5e-14
Identities = 85/357 (23%), Positives = 162/357 (45%), Gaps = 56/357 (15%)
Query: 158 KCSKEEKLSLMQSLDDAT-KQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQ-ELT 215
K K+++L+ ++ L+ A K+L+ R+T+ + K++L K E AS + A + + E T
Sbjct: 1059 KEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPT 1118
Query: 216 NEKEKALQAQV-QYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDST 274
K +AL+A+V + +QQ ++Q++ + L + LEA ER DS
Sbjct: 1119 GPKLEALRAEVSKLEQQCQKQQEQADSLERS-----------LEAERASRAER----DSA 1163
Query: 275 IRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDK 334
+ L+ +L +EL ++ + S +RE + + + K ++ + +VA QE + K
Sbjct: 1164 LETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERK 1223
Query: 335 DQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDL 394
+ L+ +E + Q VLE+ GE K L ++ +E +KL+
Sbjct: 1224 NSLISSLEEEVSILNRQ--VLEKEGES------------KELKRLVMAESEKSQKLE--- 1266
Query: 395 KTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATV 454
+L+L T AE+ L++E + L++ + R+ + L+++L +
Sbjct: 1267 ----ERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASE---NLRQELTSQA 1319
Query: 455 KKLEESKQLLKNNEKLITWLNKELNENQLVRKQDVLGPSTTPPAHSSSNTIRSGISP 511
++ EE Q LK W K + Q + ST H+S+ + S + P
Sbjct: 1320 ERAEELGQELK------AWQEKFFQKEQAL--------STLQLEHTSTQALVSELLP 1362
Score = 75.5 bits (184), Expect = 1e-13
Identities = 81/310 (26%), Positives = 140/310 (45%), Gaps = 45/310 (14%)
Query: 163 EKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKAL 222
E L Q L Q+D L+E+ +L E+ASH L + + ELT E KA
Sbjct: 294 ETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALN-ELTEEHSKAT 352
Query: 223 QAQVQYQQQHEQQK----KDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIREL 278
Q ++ Q Q E++ +D + L ++N LQ +LS+LE L + +
Sbjct: 353 QEWLEKQAQLEKELSAALQDKKCLEEKN-EILQGKLSQLEEHLSQLQDNP-------PQE 404
Query: 279 KAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLV 338
K ++ G +L+ KQE +L N+ QLQ +V +LE E ++ +
Sbjct: 405 KGEVLGDVLQLETLKQEAATLAANNT--------------QLQARVEMLETERGQQEAKL 450
Query: 339 LRTKEAFDTIQEQKVVL---------------EENGEKNQVQLGKLEATIKSLSAELLKA 383
L + F+ ++Q L EE + +Q +L A + SL++EL
Sbjct: 451 LAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTL 510
Query: 384 NEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEV 443
N I++ +L L + K K Q + L ++E+ Q + +++ + SL+ KEQ++
Sbjct: 511 NATIQQQDQELAGLKQQAKEKQA---QLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQL 567
Query: 444 CKLQEQLEAT 453
++ E+ EAT
Sbjct: 568 KEVAEKQEAT 577
Score = 67.0 bits (162), Expect = 5e-11
Identities = 84/375 (22%), Positives = 161/375 (42%), Gaps = 61/375 (16%)
Query: 160 SKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKE 219
++ EK L + +++ ++ R+ E + ++ +L L + Q+ EKE
Sbjct: 641 AQREKAELSRKVEELQACVETARQEQHEAQAQVAELE---------LQLRSEQQKATEKE 691
Query: 220 KALQAQVQYQQQHEQQKKDLEI----LHQQN------IHQLQNRLSELEAANKDLTERKY 269
+ Q + Q Q+Q + K+ L++ L ++ + + Q +SEL+A + L E+
Sbjct: 692 RVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHK 751
Query: 270 KGDSTIRELKAKLSGVEEELQRT----KQEVLSLRRENSTLDVECHEKEKHVNQLQTKVA 325
+ + E +A G+E LQ+ + E LRRE + H E QL +VA
Sbjct: 752 RERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVA 811
Query: 326 VLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEK------------------NQVQLG 367
+ +D Q + F QEQ + L+E EK +++Q+
Sbjct: 812 AWRERYEDSQQEEAQYGAMF---QEQLMTLKEECEKARQELQEAKEKVAGIESHSELQIS 868
Query: 368 KLEATIKSLSAELLKANEII-------KKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEE 420
+ + + L A L +A + + +KL DL TL K+ + + E L+ + E
Sbjct: 869 RQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGE 928
Query: 421 KLQKEQKELQDVGQSLRIKEQEVCKLQEQ-------LEATVKKLE-ESKQLLKNNEKLIT 472
+ + +EL V + R +++ L+EQ +A ++ +E E++Q+ E+L
Sbjct: 929 QQETASREL--VKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRA 986
Query: 473 WLNKELNENQLVRKQ 487
L + + Q R Q
Sbjct: 987 ALMESQGQQQEERGQ 1001
Score = 66.6 bits (161), Expect = 7e-11
Identities = 83/350 (23%), Positives = 154/350 (44%), Gaps = 30/350 (8%)
Query: 157 LKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAAL--TNKHSQEL 214
L K+ ++++MQ D L+ + + +EL++LR++ S T L T K Q+L
Sbjct: 243 LLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQDL 302
Query: 215 TNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDST 274
EK + + ++ Q ++ DL + + + L +L+ A +LTE K
Sbjct: 303 KTEKSQ-MDRKIN---QLSEENGDLSF----KLREFASHLQQLQDALNELTEEHSKATQE 354
Query: 275 IRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDK 334
E +A+L E+EL Q+ L +N L + + E+H++QLQ + E+
Sbjct: 355 WLEKQAQL---EKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLG- 410
Query: 335 DQLVLRT-KEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKS----LSAELLKANEIIKK 389
D L L T K+ T+ L+ E + + G+ EA + + E + + +I
Sbjct: 411 DVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITD 470
Query: 390 LQGDLKTL-MGKLKLKNT-------VTIQQEKLLAEK---EEKLQKEQKELQDVGQSLRI 438
LQ + L K +L+ +T Q L +E +Q++ +EL + Q +
Sbjct: 471 LQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKE 530
Query: 439 KEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQD 488
K+ ++ + +Q E + L + L ++ K KE+ E Q +QD
Sbjct: 531 KQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQD 580
Score = 61.2 bits (147), Expect = 3e-09
Identities = 102/468 (21%), Positives = 203/468 (43%), Gaps = 87/468 (18%)
Query: 77 LVDFLAFPQKFIDLLQQCTQEHAKEIPRFL-----LQLVSPAAILDNS------------ 119
L +F + Q+ D L + T+EH+K +L L+ AA+ D
Sbjct: 327 LREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGK 386
Query: 120 ----PAFLNVVETNPFKH--------LTHLSLK----LLPGNDVEIK------------- 150
L+ ++ NP + L +LK L N+ +++
Sbjct: 387 LSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQ 446
Query: 151 --KFLA--GCLKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELD-KLRNEWASHTAA 205
K LA G + K++ SL+ L + L ++ L + Q +L + AS T+
Sbjct: 447 EAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSE 506
Query: 206 LT------NKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEA 259
LT + QEL K++A + Q Q Q +QQ++ + L Q + QL + L + E
Sbjct: 507 LTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQ-VEQLSSSLKQKEQ 565
Query: 260 ANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQ 319
K++ E K ++T ++ +L+ EE + + +E R+ + +E EKEK
Sbjct: 566 QLKEVAE---KQEATRQDHAQQLATAAEEREASLRE-----RDAALKQLEALEKEK---- 613
Query: 320 LQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAE 379
K+ +L+Q+++ ++ + + Q +K L E +L+A +++ E
Sbjct: 614 -AAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVE-------ELQACVETARQE 665
Query: 380 LLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIK 439
+A + +L+ L++ K K V ++++L +E+LQ ++ L+ SL +
Sbjct: 666 QHEAQAQVAELELQLRSEQQKATEKERVAQEKDQL----QEQLQALKESLKVTKGSLEEE 721
Query: 440 EQEVCKLQEQLEATVKKLE-ESKQLLKNNEKLITWLNKELNENQLVRK 486
++ E+ + + +L+ E++ L++ +++ KEL E + RK
Sbjct: 722 KRRAADALEEQQRCISELKAETRSLVEQHKR----ERKELEEERAGRK 765
Score = 59.3 bits (142), Expect = 1e-08
Identities = 77/335 (22%), Positives = 146/335 (43%), Gaps = 40/335 (11%)
Query: 158 KCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTN------KHS 211
+ S+ L + T +L T+ ++ QEL L+ + A L + S
Sbjct: 487 QASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQAS 546
Query: 212 QELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKG 271
Q L ++ E+ + Q +QQ ++ + E Q + QL E EA+ ++ +
Sbjct: 547 QGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQL 606
Query: 272 DSTIRELKAKLSGVEEELQ-------RTKQEVLSLRRENSTLD---------VECHEKEK 315
++ +E AKL ++++LQ + V +RE + L VE +E+
Sbjct: 607 EALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQ 666
Query: 316 HVNQLQTKVAVLEQEIKDKDQLVL---RTKEAFDTIQEQKVVLEENGEKNQVQLGKLEAT 372
H + Q +VA LE +++ + Q R + D +QEQ L+E+ +V G LE
Sbjct: 667 H--EAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKES---LKVTKGSLEEE 721
Query: 373 IKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDV 432
+ + L + I +L+ + ++L+ + K ++ K L E+ + + LQ +
Sbjct: 722 KRRAADALEEQQRCISELKAETRSLVEQHK-------RERKELEEERAGRKGLEARLQQL 774
Query: 433 GQSLRIKEQEVCK--LQEQLEATVKKLEESKQLLK 465
G++ + E EV + L E + A E +QL+K
Sbjct: 775 GEAHQ-AETEVLRRELAEAMAAQHTAESECEQLVK 808
Score = 57.0 bits (136), Expect = 5e-08
Identities = 106/495 (21%), Positives = 213/495 (43%), Gaps = 49/495 (9%)
Query: 3 QVLFHQLVPLQVKCKDCEERRVSIRMSIELQSVSNPVHRKDLVIRLTDDTDPFFLYNLVI 62
+ L ++ L+ +C+ +E+ S+ S+E + S +D +
Sbjct: 1123 EALRAEVSKLEQQCQKQQEQADSLERSLEAERASRA--ERDSALETLQGQ---------- 1170
Query: 63 SEEDFQSLKFQQGLLVDFLAFPQKFIDLLQQCTQEHAKEIPRFLLQLVSPAAILDNSPAF 122
EE Q L Q L A Q+ + + Q+H+K + Q+ + +
Sbjct: 1171 LEEKAQELGHSQSAL----ASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSL 1226
Query: 123 LNVVETNPFKHLTHLSLKLLP--GNDVEIKKF-LAGCLKCSK-EEKLSLMQSLDDATKQL 178
++ +E + ++ L+ ++L G E+K+ +A K K EE+L L+Q+ + A+
Sbjct: 1227 ISSLE----EEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQA-ETASNSA 1281
Query: 179 DFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKA--LQAQVQYQQQHEQQK 236
++ A ++E+ LR E A N QELT++ E+A L +++ Q+ QK
Sbjct: 1282 RAAERSSA-LREEVQSLREEAEKQRVASENLR-QELTSQAERAEELGQELKAWQEKFFQK 1339
Query: 237 KDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEV 296
+Q + LQ + +A +L K+ E A EEL+++KQ
Sbjct: 1340 -------EQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAA 1392
Query: 297 LSLRRENSTLDVECHE----KEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQK 352
LR E E E ++K Q +T + ++ +QL + K+A + E+
Sbjct: 1393 GGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSM-LKKAHGLLAEEN 1451
Query: 353 VVLEENGEKN----QVQLGKL-EATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTV 407
L E +V+L + E ++ L+A A + ++Q + ++ +L++
Sbjct: 1452 RGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAK 1511
Query: 408 TIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNN 467
+ + E+ ++ Q+E+++L + L + ++E K Q+E KKL +S Q K
Sbjct: 1512 YEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTK---QVEELSKKLADSDQASKVQ 1568
Query: 468 EKLITWLNKELNENQ 482
++ + + + E+Q
Sbjct: 1569 QQKLKAVQAQGGESQ 1583
Score = 54.7 bits (130), Expect = 3e-07
Identities = 85/359 (23%), Positives = 149/359 (41%), Gaps = 73/359 (20%)
Query: 125 VVETNPFKHLTHLSLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFT--- 181
V E P KHL + L +K L+ SK+ L L A ++L
Sbjct: 1357 VSELLPAKHLC----QQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPL 1412
Query: 182 RKTLAEKKQELDKLRNEWASHTAALTN-KHSQELTNEKEKALQAQVQYQQQHEQQKKDLE 240
R+ +AE+++ +LR E AS+ L+ K + L E+ + L + +Q LE
Sbjct: 1413 RQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQF------LE 1466
Query: 241 ILHQQNIHQLQNRLSELEA-ANKDLTERKYKGDSTIRELK---AKLSGVE----EELQRT 292
+ Q + L+ + A A L E + + ST REL+ AK G + EE QR
Sbjct: 1467 VELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRF 1526
Query: 293 KQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQK 352
++E L + L+V E+ K V +L K+A +Q K +Q+QK
Sbjct: 1527 QEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASK---------------VQQQK 1571
Query: 353 V-VLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQ 411
+ ++ G ++Q + +L+A + L A+L
Sbjct: 1572 LKAVQAQGGESQQEAQRLQAQLNELQAQL------------------------------- 1600
Query: 412 EKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKL 470
++KE+ + + +++ K+Q+ +LQEQL + + +E+K+L E+L
Sbjct: 1601 ----SQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERL 1655
Score = 53.9 bits (128), Expect = 5e-07
Identities = 66/309 (21%), Positives = 142/309 (45%), Gaps = 46/309 (14%)
Query: 198 EWASHTAALT--NKHSQELTNEKEKA----LQAQVQYQQQHEQQKKDLEILHQQNIHQLQ 251
++ S AAL + ++++ NE E+ +++Q Q Q++ QQ++++ L Q+ + Q
Sbjct: 959 QFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQER-GRAQ 1017
Query: 252 NRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRT-------KQEVLSLRRENS 304
L+ +AA +L R + + E + + + ++E L QE+ LR +
Sbjct: 1018 ADLALEKAARAELEMRL---QNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEA 1074
Query: 305 TLDVECHEKEKHVNQLQTKVAVLEQEIKD----KDQLVLRTKEA---FDTIQEQKVVLEE 357
E E + V QL+ ++A E+E + + RT+ + ++ + LE+
Sbjct: 1075 AQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQ 1134
Query: 358 NGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAE 417
+K Q Q LE ++++ A + + ++ LQG L+ ++ + L
Sbjct: 1135 QCQKQQEQADSLERSLEAERASRAERDSALETLQGQLE--------------EKAQELGH 1180
Query: 418 KEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATV----KKLEESKQLLKNNEKLITW 473
+ L Q+EL + R K Q+ K +++ +A V ++ E L+ + E+ ++
Sbjct: 1181 SQSALASAQREL----AAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSI 1236
Query: 474 LNKELNENQ 482
LN+++ E +
Sbjct: 1237 LNRQVLEKE 1245
Score = 41.2 bits (95), Expect = 0.003
Identities = 49/272 (18%), Positives = 121/272 (44%), Gaps = 38/272 (13%)
Query: 209 KHSQELTNEKEKALQAQVQYQQQHEQQKKDLEIL-----------------HQQNIHQLQ 251
K+ QEL + A + Q++ + ++LE++ Q+ +L
Sbjct: 1475 KYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLT 1534
Query: 252 NRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECH 311
++ +LE ++ T++ + EL KL+ ++ + +Q++ +++ + E
Sbjct: 1535 AQVEQLEVFQREQTKQ-------VEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQ 1587
Query: 312 EKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEE---NGEKNQVQLGK 368
+ +N+LQ +++ EQ + + + K +D ++Q L+E + E+ Q + +
Sbjct: 1588 RLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKE 1647
Query: 369 LEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKE 428
L A + L EL +A K+ + + L +++ E +A +++L ++ +
Sbjct: 1648 LRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVR-------SLEAQVAHADQQL-RDLGK 1699
Query: 429 LQDVGQSLRIKEQEVCKLQEQLEATVKKLEES 460
Q +L+ +E + + QL+ ++ L+ S
Sbjct: 1700 FQVATDALKSREPQA---KPQLDLSIDSLDLS 1728
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 76.6 bits (187), Expect = 7e-14
Identities = 73/336 (21%), Positives = 155/336 (46%), Gaps = 26/336 (7%)
Query: 161 KEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEK 220
++++ + L + L ++ L ++K EL ++ AS+ AL+ S N +
Sbjct: 1197 RKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKS----NIERT 1252
Query: 221 ALQAQVQYQQQHEQQKKDLEILHQQNIH---------QLQNRLSELEAANKDLTERKYKG 271
+ Q+ + + ++ +++H N+ +L +R+ E E+ LT+ K
Sbjct: 1253 CRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQAL 1312
Query: 272 DSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEI 331
+ ELK ++ + + S R + L + E+++ +LQ ++ E+
Sbjct: 1313 TQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEV 1372
Query: 332 KDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQ 391
RTK D IQ + LEE +K +L + E ++ +++ + ++LQ
Sbjct: 1373 AQ-----WRTKYETDAIQRTEE-LEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQ 1426
Query: 392 GDLKTLMGKLKLKNTV--TIQQ-----EKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVC 444
G+++ LM L+ +T T+ + +K+LAE ++KL + Q EL+ + R E+
Sbjct: 1427 GEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELF 1486
Query: 445 KLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNE 480
K++ E V +LE ++ KN ++ I+ L +++ E
Sbjct: 1487 KMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAE 1522
Score = 75.1 bits (183), Expect = 2e-13
Identities = 84/317 (26%), Positives = 151/317 (47%), Gaps = 37/317 (11%)
Query: 183 KTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEIL 242
K +A K++ ++ + E A A +EL + LQ + Q Q + + ++L
Sbjct: 851 KEMATMKEDFERTKEELARSEA-----RRKELEEKMVSLLQEKNDLQLQVQSETENLMDA 905
Query: 243 HQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRE 302
++ +++++ LEA K+LTER + + EL AK +E++ K+++ L
Sbjct: 906 EERCEGLIKSKIL-LEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELT 964
Query: 303 NSTLDVECHEKEKHVNQLQTKVAVLEQEI----KDKDQLVLRTKEAFDTIQ--EQKVVLE 356
+ ++ E H E V L ++ LE+ I K+K L ++ D +Q E KV
Sbjct: 965 LTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKV--- 1021
Query: 357 ENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDL----KTLMGKLKLKNTVTIQQE 412
NG L K+ A ++ + +L + E KKL+ DL + L G LK+ + E
Sbjct: 1022 -NG------LIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLE 1074
Query: 413 KLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQ-----EQLEATVKKLEESKQ----L 463
+ EEKL+K++ EL + +I +++V LQ ++L+A +++LEE + L
Sbjct: 1075 NDKQQIEEKLKKKEFELSQL--QAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTL 1132
Query: 464 LKNNEKLITWLNKELNE 480
EK + L +EL E
Sbjct: 1133 RAKIEKQRSDLARELEE 1149
Score = 72.4 bits (176), Expect = 1e-12
Identities = 71/330 (21%), Positives = 147/330 (44%), Gaps = 40/330 (12%)
Query: 162 EEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKA 221
EEK SL+ L + + L + L + +E K +N A A +++H +L E+ +
Sbjct: 1296 EEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAH--ALQSSRHDCDLLREQYEE 1353
Query: 222 LQAQVQYQQQHEQQKKDLEILHQQNIHQLQ--NRLSELEAANKDLTERKYKGDSTIRELK 279
Q + + + Q K + E+ + ++ R ELE A K L +R + +
Sbjct: 1354 EQ-EAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETAN 1412
Query: 280 AKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVL 339
+K + +E+ QR + EV L R+ + + T A L+++ ++ D+++
Sbjct: 1413 SKCASLEKTKQRLQGEVEDLMRD--------------LERSHTACATLDKKQRNFDKVLA 1458
Query: 340 RTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMG 399
K+ D ++Q +L + +SLS EL K +++ L+TL
Sbjct: 1459 EWKQKLD--------------ESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRR 1504
Query: 400 KLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEE 459
+ K +Q+E +++ E++ + K LQ+ ++ ++ EQE LQ LE LE
Sbjct: 1505 ENK-----NLQEE--ISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEH 1557
Query: 460 SKQLLKNNEKLITWLNKELNENQLVRKQDV 489
+ + + ++ + EL+ + + +++
Sbjct: 1558 EESKILRVQLELSQVKSELDRKVIEKDEEI 1587
Score = 69.7 bits (169), Expect = 8e-12
Identities = 72/338 (21%), Positives = 156/338 (46%), Gaps = 33/338 (9%)
Query: 175 TKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQH-- 232
T++L+ +K LA++ QE ++ E A+ A K Q L E E ++ ++ H
Sbjct: 1387 TEELEEAKKKLAQRLQEAEE-NTETANSKCASLEKTKQRLQGEVEDLMR---DLERSHTA 1442
Query: 233 ----EQQKKDLEILHQQNIHQLQNRLSELEAANKD---LTERKYKGDSTIRELKAKLSGV 285
++++++ + + + +L +ELEAA K+ L+ +K + E+ +L +
Sbjct: 1443 CATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETL 1502
Query: 286 EEELQRTKQEVLSLRRENSTLDVECHEKEK-------HVNQLQTKVAVLEQEIKDKDQLV 338
E + ++E+ L + + E EK + LQ + +E ++ ++ +
Sbjct: 1503 RRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKI 1562
Query: 339 LRTKEAFDTIQEQ--KVVLEENGEKNQVQLGK---LEATIKSLSAELLKANEII---KKL 390
LR + ++ + + V+E++ E Q++ EA L AE+ N+ + KK+
Sbjct: 1563 LRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKM 1622
Query: 391 QGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQL 450
+GDL + +L N + +K L + +L+ Q L D +S ++++ ++ +
Sbjct: 1623 EGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRN 1682
Query: 451 EATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQD 488
+++LEE K L+ E+ + L+E +L+ D
Sbjct: 1683 GLLLEELEEMKVALEQTER-----TRRLSEQELLDASD 1715
Score = 66.2 bits (160), Expect = 9e-11
Identities = 69/307 (22%), Positives = 138/307 (44%), Gaps = 18/307 (5%)
Query: 183 KTLAEKKQELDKLRNEWASHTAALTNKHSQELTN--EKEKALQAQVQYQQQHEQQKKDLE 240
K L+E+ L++ ++ +L H Q L + +E + ++ + EQQ DLE
Sbjct: 980 KNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLE 1039
Query: 241 ILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLR 300
++ Q + ++LE A + L +I +L+ +EE+L++ + E+ L+
Sbjct: 1040 ----GSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQ 1095
Query: 301 RENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLR-TKEAFDTIQEQKVVLEENG 359
+ V + +K + +LQ ++ LE+EI+ + L + K+ D +E LEE
Sbjct: 1096 AKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARE----LEEIS 1151
Query: 360 EKNQVQLGKLEATI---KSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTI----QQE 412
E+ + G A I K AE K +++ + L+ K ++ +Q
Sbjct: 1152 ERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQI 1211
Query: 413 KLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLIT 472
L ++KL+KE+ EL+ + + + K + +E T + +E+ +K ++ T
Sbjct: 1212 DNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQT 1271
Query: 473 WLNKELN 479
L +LN
Sbjct: 1272 QLIHDLN 1278
Score = 48.9 bits (115), Expect = 1e-05
Identities = 52/225 (23%), Positives = 103/225 (45%), Gaps = 24/225 (10%)
Query: 277 ELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQ 336
E + +++ ++E+ +RTK+E+ L+ + + N LQ +V + + D ++
Sbjct: 848 EAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEE 907
Query: 337 L---VLRTKEAFDT-IQEQKVVLEENGEKNQVQLGK---LEATIKSLSAELLKANEIIKK 389
++++K + ++E LEE E N + K LE SL ++ + K
Sbjct: 908 RCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTK 967
Query: 390 LQGDLKTLMGKLK-LKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQ----SLRIKEQEV- 443
++ + K+K L +T +E + KL KE+K LQ+ Q L+++E +V
Sbjct: 968 VEKEKHATENKVKNLSEEMTALEENI-----SKLTKEKKSLQEAHQQTLDDLQVEEDKVN 1022
Query: 444 ------CKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQ 482
KL++Q + LE+ K+L + E+ L +L +Q
Sbjct: 1023 GLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQ 1067
Score = 46.2 bits (108), Expect = 1e-04
Identities = 66/329 (20%), Positives = 138/329 (41%), Gaps = 34/329 (10%)
Query: 157 LKCSKEEKLSLMQ-SLDDATKQLDFTRKTLAEKKQEL--------DKLR-NEWASHTAAL 206
LK E L+ M+ L + +Q+ T+K L + +L D LR NE A+
Sbjct: 1618 LKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAI 1677
Query: 207 TNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTE 266
+ + L E E+ A Q ++ L +Q + +R+ L + N L
Sbjct: 1678 VERRNGLLLEELEEMKVALEQTERTRR--------LSEQELLDASDRVQLLHSQNTSLIN 1729
Query: 267 RKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAV 326
K K ++ I + +A++ +E + +++ + + + E +++ L+
Sbjct: 1730 TKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1789
Query: 327 LEQEIKD-------KDQLVL--------RTKEAFDTIQEQKVVLEENGEKNQVQLGKLEA 371
LEQ +KD +QL L + + ++ + V ++ G + K E
Sbjct: 1790 LEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYER 1849
Query: 372 TIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQD 431
+K ++ + + ++ I +LQ + L K+K + E+ + + ++ Q EL++
Sbjct: 1850 KVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEE 1909
Query: 432 VGQSLRIKEQEVCKLQ-EQLEATVKKLEE 459
+ I E +V KL+ + + +K+EE
Sbjct: 1910 AAERADIAESQVNKLRAKSRDVGSQKMEE 1938
Score = 43.1 bits (100), Expect = 8e-04
Identities = 65/366 (17%), Positives = 163/366 (44%), Gaps = 49/366 (13%)
Query: 155 GCLKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQEL 214
G L+ + + L + L +LD + + EK +E+++L+ AL + E+
Sbjct: 1553 GSLEHEESKILRVQLELSQVKSELD---RKVIEKDEEIEQLKRNSQRAAEALQSVLDAEI 1609
Query: 215 TNEKEKALQAQVQYQQQHEQQKKDLEILH--------QQNIHQLQNRLSELEA------- 259
+ + +++ + + + + ++++ H Q+++ +Q +L + +
Sbjct: 1610 RSRNDAL---RLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALR 1666
Query: 260 ANKDLTERKYKGD-------STIRELKAKLSGVEEELQRTKQEVLS-------LRRENST 305
+N+DL E+ + + E+K L E + ++QE+L L +N++
Sbjct: 1667 SNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTS 1726
Query: 306 LDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFD--TIQEQKVVLEENGEKNQ 363
L + E + Q Q +V QE ++ ++ + K+A + +++ E++ +
Sbjct: 1727 LINTKKKLEADIAQCQAEVENSIQESRNAEE---KAKKAITDAAMMAEELKKEQDTSAHL 1783
Query: 364 VQLGK-LEATIKSLSAELLKANEI--------IKKLQGDLKTLMGKLKLKNTVTIQQEKL 414
++ K LE T+K L L +A ++ I+KL+ ++ L +L ++ + K
Sbjct: 1784 ERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKG 1843
Query: 415 LAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWL 474
+ E K+++ + ++ +++ + V KLQ ++++ ++ EE+++ +
Sbjct: 1844 AHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRV 1903
Query: 475 NKELNE 480
EL E
Sbjct: 1904 QHELEE 1909
Score = 37.0 bits (84), Expect = 0.058
Identities = 44/167 (26%), Positives = 77/167 (46%), Gaps = 15/167 (8%)
Query: 323 KVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLK 382
K A E+E+ + RTKE + ++ LEE + L+ ++S + L+
Sbjct: 845 KSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMD 904
Query: 383 ANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKE--EKLQKEQKELQDVGQSLRIK- 439
A E + +G +K+ K+ L+ V E+L E+E +L +++ L+D SL+
Sbjct: 905 AEE---RCEGLIKS---KILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDI 958
Query: 440 ---EQEVCKLQEQLEAT---VKKLEESKQLLKNNEKLITWLNKELNE 480
E + K++++ AT VK L E L+ N +T K L E
Sbjct: 959 DDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQE 1005
>gi|219555661 intraflagellar transport 81-like isoform 1 [Homo
sapiens]
Length = 676
Score = 76.6 bits (187), Expect = 7e-14
Identities = 100/471 (21%), Positives = 202/471 (42%), Gaps = 86/471 (18%)
Query: 72 FQQGLLVDFLAFPQKFIDLLQQCTQEHAKE--IPRFLLQLVSPAAIL------DNSPAFL 123
F+QGL++ + L Q T E K + RFL++L P+ L D + +
Sbjct: 86 FRQGLVIGSKPVIYPVLHWLLQRTNELKKRAYLARFLIKLEVPSEFLQDETVADTNKQYE 145
Query: 124 NVVETNPFKHLTHLSLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFTR- 182
++E H + LK+ + EI+K ++ +EEK L++ ++ K+++ +
Sbjct: 146 ELMEAFKTLHKEYEQLKISGFSTAEIRKDISAM----EEEKDQLIKRVEHLKKRVETAQN 201
Query: 183 ------------------KTLAEKKQE-----------LDKLRNEWASHTAALTNKHSQE 213
+ LA++KQE L +++N+ S A + +
Sbjct: 202 HQWMLKIARQLRVEKEREEYLAQQKQEQKNQLFHAVQRLQRVQNQLKSMRQAAADAKPES 261
Query: 214 LTNEKEKALQAQV-----QYQQQHEQQKKDLEILHQ---------QNIHQLQNRLSELEA 259
L E+ ++ + ++ ++ E +KK+L L + ++ +L+++++E+
Sbjct: 262 LMKRLEEEIKFNLYMVTEKFPKELENKKKELHFLQKVVSEPAMGHSDLLELESKINEINT 321
Query: 260 ANKDLTERKYKGDSTIRE-----------LKAKLSGVEEELQRTKQEVLSLRRENS---- 304
L E+K + I + K EELQ K+++ SL RE S
Sbjct: 322 EINQLIEKKMMRNEPIEGKLSLYRQQASIISRKKEAKAEELQEAKEKLASLEREASVKRN 381
Query: 305 -------TLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEE 357
T ++ E +++VN+L++K V K K Q++ K F +Q + +L++
Sbjct: 382 QTREFDGTEVLKGDEFKRYVNKLRSKSTVF----KKKHQIIAELKAEFGLLQRTEELLKQ 437
Query: 358 NGEKNQVQLGKLEATIKSLSAELLKANEI--IKKLQGDLKTLMGK-LKLKNTVTIQQEKL 414
E Q QL +E K +S E+ + L+ ++ + G+ L + + + L
Sbjct: 438 RHENIQQQLQTMEEK-KGISGYSYTQEELERVSALKSEVDEMKGRTLDDMSEMVKKLYSL 496
Query: 415 LAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLK 465
++EK+ L KEL+ + Q + QE + + Q ++ LE ++ L+
Sbjct: 497 VSEKKSALASVIKELRQLRQKYQELTQECDEKKSQYDSCAAGLESNRSKLE 547
Score = 35.4 bits (80), Expect = 0.17
Identities = 49/193 (25%), Positives = 86/193 (44%), Gaps = 31/193 (16%)
Query: 163 EKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHS---QELTNEKE 219
EK S + S+ +QL R+ E QE D+ ++++ S A L + S QE+ +E
Sbjct: 499 EKKSALASVIKELRQL---RQKYQELTQECDEKKSQYDSCAAGLESNRSKLEQEVRRLRE 555
Query: 220 KALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELK 279
+ LQ + +Y + K+LE+ QL+ E++A + K K IRE
Sbjct: 556 ECLQEESRYHYTN-CMIKNLEV-------QLRRATDEMKAYISSDQQEKRK---AIREQY 604
Query: 280 AKLSGVEEELQRTKQEVLSLRRENSTLD-------------VECHEKEKHVNQLQTKVAV 326
K + +E L + +E + RE+ + +EC ++ Q QT +
Sbjct: 605 TKNTAEQENLGKKLREKQKVIRESHGPNMKQAKMWRDLEQLMECKKQCFLKQQSQTSIGQ 664
Query: 327 LEQEIKDKDQLVL 339
+ QE +D+L+L
Sbjct: 665 VIQE-GGEDRLIL 676
Score = 31.2 bits (69), Expect = 3.2
Identities = 44/216 (20%), Positives = 89/216 (41%), Gaps = 47/216 (21%)
Query: 189 KQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIH 248
K E+D+++ + + K L +EK+ AL + ++ +
Sbjct: 472 KSEVDEMKGRTLDDMSEMVKK-LYSLVSEKKSALASVIK------------------ELR 512
Query: 249 QLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDV 308
QL+ + EL ++ E+K + DS L++ S +E+E++R ++
Sbjct: 513 QLRQKYQEL---TQECDEKKSQYDSCAAGLESNRSKLEQEVRRLRE-------------- 555
Query: 309 ECHEKEKHVNQLQTKVAVLEQEIK---DKDQLVLRTKEAFDTIQEQKVVLEENGEKN--- 362
EC ++E + + LE +++ D+ + + + + QE++ + E KN
Sbjct: 556 ECLQEESRYHYTNCMIKNLEVQLRRATDEMKAYISSDQ-----QEKRKAIREQYTKNTAE 610
Query: 363 QVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLM 398
Q LGK + + E N K+ DL+ LM
Sbjct: 611 QENLGKKLREKQKVIRESHGPNMKQAKMWRDLEQLM 646
>gi|32526901 intraflagellar transport 81-like isoform 1 [Homo
sapiens]
Length = 676
Score = 76.6 bits (187), Expect = 7e-14
Identities = 100/471 (21%), Positives = 202/471 (42%), Gaps = 86/471 (18%)
Query: 72 FQQGLLVDFLAFPQKFIDLLQQCTQEHAKE--IPRFLLQLVSPAAIL------DNSPAFL 123
F+QGL++ + L Q T E K + RFL++L P+ L D + +
Sbjct: 86 FRQGLVIGSKPVIYPVLHWLLQRTNELKKRAYLARFLIKLEVPSEFLQDETVADTNKQYE 145
Query: 124 NVVETNPFKHLTHLSLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFTR- 182
++E H + LK+ + EI+K ++ +EEK L++ ++ K+++ +
Sbjct: 146 ELMEAFKTLHKEYEQLKISGFSTAEIRKDISAM----EEEKDQLIKRVEHLKKRVETAQN 201
Query: 183 ------------------KTLAEKKQE-----------LDKLRNEWASHTAALTNKHSQE 213
+ LA++KQE L +++N+ S A + +
Sbjct: 202 HQWMLKIARQLRVEKEREEYLAQQKQEQKNQLFHAVQRLQRVQNQLKSMRQAAADAKPES 261
Query: 214 LTNEKEKALQAQV-----QYQQQHEQQKKDLEILHQ---------QNIHQLQNRLSELEA 259
L E+ ++ + ++ ++ E +KK+L L + ++ +L+++++E+
Sbjct: 262 LMKRLEEEIKFNLYMVTEKFPKELENKKKELHFLQKVVSEPAMGHSDLLELESKINEINT 321
Query: 260 ANKDLTERKYKGDSTIRE-----------LKAKLSGVEEELQRTKQEVLSLRRENS---- 304
L E+K + I + K EELQ K+++ SL RE S
Sbjct: 322 EINQLIEKKMMRNEPIEGKLSLYRQQASIISRKKEAKAEELQEAKEKLASLEREASVKRN 381
Query: 305 -------TLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEE 357
T ++ E +++VN+L++K V K K Q++ K F +Q + +L++
Sbjct: 382 QTREFDGTEVLKGDEFKRYVNKLRSKSTVF----KKKHQIIAELKAEFGLLQRTEELLKQ 437
Query: 358 NGEKNQVQLGKLEATIKSLSAELLKANEI--IKKLQGDLKTLMGK-LKLKNTVTIQQEKL 414
E Q QL +E K +S E+ + L+ ++ + G+ L + + + L
Sbjct: 438 RHENIQQQLQTMEEK-KGISGYSYTQEELERVSALKSEVDEMKGRTLDDMSEMVKKLYSL 496
Query: 415 LAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLK 465
++EK+ L KEL+ + Q + QE + + Q ++ LE ++ L+
Sbjct: 497 VSEKKSALASVIKELRQLRQKYQELTQECDEKKSQYDSCAAGLESNRSKLE 547
Score = 35.4 bits (80), Expect = 0.17
Identities = 49/193 (25%), Positives = 86/193 (44%), Gaps = 31/193 (16%)
Query: 163 EKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHS---QELTNEKE 219
EK S + S+ +QL R+ E QE D+ ++++ S A L + S QE+ +E
Sbjct: 499 EKKSALASVIKELRQL---RQKYQELTQECDEKKSQYDSCAAGLESNRSKLEQEVRRLRE 555
Query: 220 KALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELK 279
+ LQ + +Y + K+LE+ QL+ E++A + K K IRE
Sbjct: 556 ECLQEESRYHYTN-CMIKNLEV-------QLRRATDEMKAYISSDQQEKRK---AIREQY 604
Query: 280 AKLSGVEEELQRTKQEVLSLRRENSTLD-------------VECHEKEKHVNQLQTKVAV 326
K + +E L + +E + RE+ + +EC ++ Q QT +
Sbjct: 605 TKNTAEQENLGKKLREKQKVIRESHGPNMKQAKMWRDLEQLMECKKQCFLKQQSQTSIGQ 664
Query: 327 LEQEIKDKDQLVL 339
+ QE +D+L+L
Sbjct: 665 VIQE-GGEDRLIL 676
Score = 31.2 bits (69), Expect = 3.2
Identities = 44/216 (20%), Positives = 89/216 (41%), Gaps = 47/216 (21%)
Query: 189 KQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIH 248
K E+D+++ + + K L +EK+ AL + ++ +
Sbjct: 472 KSEVDEMKGRTLDDMSEMVKK-LYSLVSEKKSALASVIK------------------ELR 512
Query: 249 QLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDV 308
QL+ + EL ++ E+K + DS L++ S +E+E++R ++
Sbjct: 513 QLRQKYQEL---TQECDEKKSQYDSCAAGLESNRSKLEQEVRRLRE-------------- 555
Query: 309 ECHEKEKHVNQLQTKVAVLEQEIK---DKDQLVLRTKEAFDTIQEQKVVLEENGEKN--- 362
EC ++E + + LE +++ D+ + + + + QE++ + E KN
Sbjct: 556 ECLQEESRYHYTNCMIKNLEVQLRRATDEMKAYISSDQ-----QEKRKAIREQYTKNTAE 610
Query: 363 QVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLM 398
Q LGK + + E N K+ DL+ LM
Sbjct: 611 QENLGKKLREKQKVIRESHGPNMKQAKMWRDLEQLM 646
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 76.3 bits (186), Expect = 9e-14
Identities = 75/324 (23%), Positives = 155/324 (47%), Gaps = 23/324 (7%)
Query: 181 TRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLE 240
TR T +KK K+ N T HS E +EK+ + Q Q +++ E Q +
Sbjct: 42 TRATDTKKK----KINNGTNPETTTSEGCHSPE--DEKKASHQHQEALRREIEAQDHTIR 95
Query: 241 ILHQQN------IHQLQNRLSELEAAN----KDLTERKYKGDSTIRELKAKLSGVEEELQ 290
IL Q ++ Q+ + E N KDL R + EL+ LS V +
Sbjct: 96 ILTCQKTELETALYYSQDAARKFEDGNLGESKDLAGRLHHSWHFAGELQRALSAVSTWHK 155
Query: 291 RTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIK----DKDQLVLRTKEAFD 346
+ + + L +E L +E + +L+ K A L+++++ +K ++ L KE
Sbjct: 156 KADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKR 215
Query: 347 TIQEQKVVLEENGEKN-QVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKN 405
++ K +L + Q ++ + E ++ ++ K E + + + L+ GK++ +
Sbjct: 216 KLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQE 275
Query: 406 TVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLK 465
+QEK L E+E++L++++KEL++ + LR +E+++ + +E++ +K+ E ++ +
Sbjct: 276 EKMRRQEKRLREQEKELREQEKELRE-QKKLREQEEQMQEQEEKMWEQEEKMREQEEKMW 334
Query: 466 NNEKLITWLNKELNE-NQLVRKQD 488
E+ + K++ E Q +R Q+
Sbjct: 335 RQEERLWEQEKQMREQEQKMRDQE 358
Score = 69.3 bits (168), Expect = 1e-11
Identities = 58/314 (18%), Positives = 163/314 (51%), Gaps = 14/314 (4%)
Query: 161 KEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLR-NEWASHTAALTNKHSQELTNEKE 219
+EEK+ + + + K++ +T+ E+++++ K N W Q L +KE
Sbjct: 384 QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEW---QQQRLPEQKE 440
Query: 220 KALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELK 279
K + + +Q+ + +++ +I Q+ + + ++ E ++ ++ ++ + +R+ +
Sbjct: 441 KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM-REQEDQMWEQEEKMRDQE 499
Query: 280 AKLSGVEEEL----QRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKD 335
K+ EE + +R +++ +R + E +E+ Q Q K +QE K ++
Sbjct: 500 QKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEK-KTWDQEEKMRE 558
Query: 336 QLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLK 395
+ +R +E ++E++ ++ E EK Q Q K+ + + + K E +K+ + +
Sbjct: 559 EERMREREK--KMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW-EQE 615
Query: 396 TLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVK 455
M + + ++ + +QE+++ E+EEK+Q++++++ + + +R +E+++ + +E+++ +
Sbjct: 616 EKMWEQEEEDKMQ-EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 674
Query: 456 KLEESKQLLKNNEK 469
K+ E ++ ++ E+
Sbjct: 675 KMREQEEKMQGQEE 688
Score = 67.8 bits (164), Expect = 3e-11
Identities = 57/297 (19%), Positives = 147/297 (49%), Gaps = 29/297 (9%)
Query: 212 QELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKG 271
Q++ +++E+ + + +++ E+ ++ ++ Q+ + + + E E D E K +
Sbjct: 500 QKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWD-QEEKMRE 558
Query: 272 DSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEI 331
+ +RE + K+ EEE+ R ++E + + E + E+E+ + + + K+ E+++
Sbjct: 559 EERMREREKKMRE-EEEMMREQEEKMQEQEE------KMREQEEKMWEQEEKMQEQEEKM 611
Query: 332 KDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQ 391
++++ + +E D +QEQ+ ++ E EK Q Q K+ + + + K E +K+Q
Sbjct: 612 WEQEEKMWEQEEE-DKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 670
Query: 392 GDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLE 451
G QE+ + E+EEK+Q +++++++ + +R +E+++ +E++
Sbjct: 671 G------------------QEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMW 712
Query: 452 ATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQDVLGPSTTPPAHSSSNTIRSG 508
+K+ +++ + E++ KE + +L ++ PP+ N +G
Sbjct: 713 GQEEKMWGQEEMREKEERIRD--QKEKMQERLPEHEERCSEPCLPPSKVLCNMSHTG 767
Score = 65.9 bits (159), Expect = 1e-10
Identities = 69/350 (19%), Positives = 163/350 (46%), Gaps = 44/350 (12%)
Query: 146 DVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAA 205
++E + L C K E + + DA ++ F L E K +L + W
Sbjct: 86 EIEAQDHTIRILTCQKTELETALYYSQDAARK--FEDGNLGESKDLAGRLHHSW------ 137
Query: 206 LTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQ----NIHQLQNRLS--ELEA 259
E ++AL A + H++ + +E L ++ ++ +N ++ EL+
Sbjct: 138 -------HFAGELQRALSAVSTW---HKKADRYIEELTKERDALSLELYRNTITNEELKK 187
Query: 260 ANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQ 319
N +L E+ +S E++ + ++ +L+R K L + + +TL E +E+ + +
Sbjct: 188 KNAELQEKLRLAESEKSEIQLNVKELKRKLERAK--FLLPQVQTNTLQEEMWRQEEELRE 245
Query: 320 LQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAE 379
+ K+ E+++ +++ ++EQ+ + E EK + Q +L K L +
Sbjct: 246 QEKKIRKQEEKMWRQEE----------RLREQEGKMREQEEKMRRQEKRLREQEKELREQ 295
Query: 380 LLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIK 439
+ E Q L+ +++ + +QE+ + E+EEK+ ++++ L + + +R +
Sbjct: 296 EKELRE-----QKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ 350
Query: 440 EQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKE-LNENQLVRKQD 488
EQ++ +E++ ++L E ++ ++ EK+ W +E + E + +R+++
Sbjct: 351 EQKMRDQEERMWEQDERLREKEERMREQEKM--WEQEEKMQEEERIRERE 398
Score = 60.1 bits (144), Expect = 6e-09
Identities = 58/338 (17%), Positives = 166/338 (49%), Gaps = 10/338 (2%)
Query: 157 LKCSKEEKLSLMQSLDDATKQLDFTRKT--LAEKKQELDKLRNEWASHTAALTNKHSQEL 214
LK E L+ + T Q + R+ L E+++++ K + L + +
Sbjct: 213 LKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMR 272
Query: 215 TNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDST 274
E++ Q + +Q+ E ++++ E+ Q+ + + + ++ E E + E+ + +
Sbjct: 273 EQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK 332
Query: 275 IRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDK 334
+ + +L E++++ +Q++ D EKE+ + + Q K+ E++++++
Sbjct: 333 MWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMRE-QEKMWEQEEKMQEE 391
Query: 335 DQLVLRTK---EAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQ 391
+++ R K E +T++EQ+ +++ E+N + + E + L + K E K +
Sbjct: 392 ERIREREKKMREEEETMREQEEKMQKQ-EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQE 450
Query: 392 GDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLE 451
+ K + K+++ + ++ ++EK+++++ ++ + + +R +EQ++ +E++
Sbjct: 451 QEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMW 510
Query: 452 ATVKKLEESKQLLKNNEKLITWLNKE-LNENQLVRKQD 488
++L E ++ ++ +K+ W +E + E + ++Q+
Sbjct: 511 EQDERLREKEERMREQKKM--WQQEEKMREEKKTQEQE 546
Score = 43.5 bits (101), Expect = 6e-04
Identities = 44/224 (19%), Positives = 100/224 (44%), Gaps = 29/224 (12%)
Query: 161 KEEKLSLMQSLDDATKQLDFTRKTLAEKKQELD---KLRNEWASHTAALTNKHSQELTNE 217
KEE++ + + +++ +KT ++K+ D K+R E + +E+ E
Sbjct: 519 KEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 578
Query: 218 KEKALQAQV-------------------QYQQQHEQQKKDLEILHQQNIHQLQNRLSELE 258
+E+ +Q Q Q ++ EQ++K E + + + + + E E
Sbjct: 579 QEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQE 638
Query: 259 AANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVN 318
++ E+ ++ + +RE + K+ EE++Q ++++ + + + E+E+ +
Sbjct: 639 EKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMR 698
Query: 319 QLQTKVAVLE-----QEIKDKDQLVLRTKEAFDTIQEQKVVLEE 357
+ K+ E QE K Q +R KE + I++QK ++E
Sbjct: 699 GQEEKMWGQEEKMWGQEEKMWGQEEMREKE--ERIRDQKEKMQE 740
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.348
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,220,575
Number of Sequences: 37866
Number of extensions: 1140585
Number of successful extensions: 17972
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 569
Number of HSP's successfully gapped in prelim test: 1000
Number of HSP's that attempted gapping in prelim test: 6148
Number of HSP's gapped (non-prelim): 6023
length of query: 657
length of database: 18,247,518
effective HSP length: 109
effective length of query: 548
effective length of database: 14,120,124
effective search space: 7737827952
effective search space used: 7737827952
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.