Guide to the Human Genome
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Search of human proteins with 34878716

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|34878716 paired box protein 2 isoform d [Homo sapiens]
         (408 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|34878716 paired box protein 2 isoform d [Homo sapiens]             838   0.0  
gi|34878703 paired box protein 2 isoform e [Homo sapiens]             825   0.0  
gi|34878701 paired box protein 2 isoform b [Homo sapiens]             758   0.0  
gi|34878699 paired box protein 2 isoform a [Homo sapiens]             745   0.0  
gi|34878709 paired box protein 2 isoform c [Homo sapiens]             693   0.0  
gi|9951920 paired box 5 [Homo sapiens]                                511   e-145
gi|7524361 paired box 8 isoform PAX8B [Homo sapiens]                  474   e-134
gi|5803117 paired box 8 isoform PAX8A [Homo sapiens]                  420   e-117
gi|7524363 paired box 8 isoform PAX8C [Homo sapiens]                  384   e-107
gi|7524365 paired box 8 isoform PAX8D [Homo sapiens]                  355   3e-98
gi|7669542 paired box 8 isoform PAX8E [Homo sapiens]                  353   1e-97
gi|189083681 paired box gene 6 isoform a [Homo sapiens]               235   5e-62
gi|4505615 paired box gene 6 isoform a [Homo sapiens]                 235   5e-62
gi|4580424 paired box gene 6 isoform b [Homo sapiens]                 226   4e-59
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]                224   1e-58
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]                 219   3e-57
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]                 219   3e-57
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]                 219   3e-57
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]                 219   3e-57
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]                  219   3e-57
gi|7524359 paired box 7 isoform 2 [Homo sapiens]                      218   6e-57
gi|4505619 paired box 7 isoform 1 [Homo sapiens]                      213   2e-55
gi|207029223 paired box 7 isoform 3 [Homo sapiens]                    213   2e-55
gi|197276661 paired box 1 [Homo sapiens]                              203   3e-52
gi|7242167 paired box 9 [Homo sapiens]                                199   3e-51
gi|7524356 paired box 3 isoform PAX3b [Homo sapiens]                  194   1e-49
gi|6654638 paired box 3 isoform PAX3a [Homo sapiens]                  194   1e-49
gi|170784824 paired box 4 [Homo sapiens]                              169   3e-42
gi|126116581 retina and anterior neural fold homeobox [Homo sapi...    44   3e-04
gi|130492454 zinc finger RNA binding protein 2 isoform 1 [Homo s...    43   4e-04

>gi|34878716 paired box protein 2 isoform d [Homo sapiens]
          Length = 408

 Score =  838 bits (2166), Expect = 0.0
 Identities = 408/408 (100%), Positives = 408/408 (100%)

Query: 1   MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
           MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
Sbjct: 1   MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60

Query: 61  SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
           SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
Sbjct: 61  SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120

Query: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
           EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
Sbjct: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180

Query: 181 PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA 240
           PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA
Sbjct: 181 PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA 240

Query: 241 LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQ 300
           LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQ
Sbjct: 241 LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQ 300

Query: 301 TYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEA 360
           TYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEA
Sbjct: 301 TYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEA 360

Query: 361 WRFSNPALLMPPPGPPLPLLPLPMTATSYRGDHIKLQADSFGLHIVPV 408
           WRFSNPALLMPPPGPPLPLLPLPMTATSYRGDHIKLQADSFGLHIVPV
Sbjct: 361 WRFSNPALLMPPPGPPLPLLPLPMTATSYRGDHIKLQADSFGLHIVPV 408


>gi|34878703 paired box protein 2 isoform e [Homo sapiens]
          Length = 431

 Score =  825 bits (2132), Expect = 0.0
 Identities = 408/431 (94%), Positives = 408/431 (94%), Gaps = 23/431 (5%)

Query: 1   MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
           MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
Sbjct: 1   MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60

Query: 61  SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
           SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
Sbjct: 61  SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120

Query: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
           EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
Sbjct: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180

Query: 181 PVGSYSINGILGIPRSNGEKRKRDE-----------------------DVSEGSVPNGDS 217
           PVGSYSINGILGIPRSNGEKRKRDE                       DVSEGSVPNGDS
Sbjct: 181 PVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDS 240

Query: 218 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 277
           QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL
Sbjct: 241 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 300

Query: 278 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 337
           DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG
Sbjct: 301 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 360

Query: 338 MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLMPPPGPPLPLLPLPMTATSYRGDHIKLQ 397
           MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLMPPPGPPLPLLPLPMTATSYRGDHIKLQ
Sbjct: 361 MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLMPPPGPPLPLLPLPMTATSYRGDHIKLQ 420

Query: 398 ADSFGLHIVPV 408
           ADSFGLHIVPV
Sbjct: 421 ADSFGLHIVPV 431


>gi|34878701 paired box protein 2 isoform b [Homo sapiens]
          Length = 393

 Score =  758 bits (1958), Expect = 0.0
 Identities = 370/372 (99%), Positives = 370/372 (99%)

Query: 1   MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
           MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
Sbjct: 1   MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60

Query: 61  SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
           SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
Sbjct: 61  SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120

Query: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
           EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
Sbjct: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180

Query: 181 PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA 240
           PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA
Sbjct: 181 PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA 240

Query: 241 LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQ 300
           LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQ
Sbjct: 241 LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQ 300

Query: 301 TYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEA 360
           TYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEA
Sbjct: 301 TYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEA 360

Query: 361 WRFSNPALLMPP 372
           WRFSNPALL  P
Sbjct: 361 WRFSNPALLSSP 372


>gi|34878699 paired box protein 2 isoform a [Homo sapiens]
          Length = 416

 Score =  745 bits (1924), Expect = 0.0
 Identities = 370/395 (93%), Positives = 370/395 (93%), Gaps = 23/395 (5%)

Query: 1   MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
           MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
Sbjct: 1   MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60

Query: 61  SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
           SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
Sbjct: 61  SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120

Query: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
           EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
Sbjct: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180

Query: 181 PVGSYSINGILGIPRSNGEKRKRDE-----------------------DVSEGSVPNGDS 217
           PVGSYSINGILGIPRSNGEKRKRDE                       DVSEGSVPNGDS
Sbjct: 181 PVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDS 240

Query: 218 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 277
           QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL
Sbjct: 241 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 300

Query: 278 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 337
           DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG
Sbjct: 301 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 360

Query: 338 MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLMPP 372
           MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALL  P
Sbjct: 361 MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSP 395


>gi|34878709 paired box protein 2 isoform c [Homo sapiens]
          Length = 396

 Score =  693 bits (1789), Expect = 0.0
 Identities = 340/340 (100%), Positives = 340/340 (100%)

Query: 1   MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
           MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
Sbjct: 1   MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60

Query: 61  SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
           SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
Sbjct: 61  SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120

Query: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
           EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
Sbjct: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180

Query: 181 PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA 240
           PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA
Sbjct: 181 PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA 240

Query: 241 LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQ 300
           LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQ
Sbjct: 241 LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQ 300

Query: 301 TYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVP 340
           TYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVP
Sbjct: 301 TYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVP 340


>gi|9951920 paired box 5 [Homo sapiens]
          Length = 391

 Score =  511 bits (1316), Expect = e-145
 Identities = 260/361 (72%), Positives = 291/361 (80%), Gaps = 11/361 (3%)

Query: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
           GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET
Sbjct: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75

Query: 76  GSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSI 135
           GSIKPGVIGGSKPKVATPKVV+KIAEYKRQNPTMFAWEIRDRLLAE +CDNDTVPSVSSI
Sbjct: 76  GSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSI 135

Query: 136 NRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVG-SYSINGILGI- 193
           NRIIRTKVQQP           V A  H+IV + +   VSS S D  G SYSI+GILGI 
Sbjct: 136 NRIIRTKVQQP-------PNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYSISGILGIT 188

Query: 194 -PRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPD 252
            P ++  KRKRDE + E  VPNG S  G D LRK +R D FTQQQLE LDRVFER  Y D
Sbjct: 189 SPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSD 248

Query: 253 VFQASEHIKSEQGNEYS-LPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMA 311
           +F  +E IK EQ  EYS + +L  GLD++K++L++ T  ++GS+V G Q+YP+VTGRD+A
Sbjct: 249 IFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYPIVTGRDLA 308

Query: 312 STTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLMP 371
           STTLPGYPPHVPP GQGSY   TL GMVPGSEFSG+PYSHPQY++YN++WRF NP LL  
Sbjct: 309 STTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRFPNPGLLGS 368

Query: 372 P 372
           P
Sbjct: 369 P 369


>gi|7524361 paired box 8 isoform PAX8B [Homo sapiens]
          Length = 387

 Score =  474 bits (1221), Expect = e-134
 Identities = 244/391 (62%), Positives = 290/391 (74%), Gaps = 10/391 (2%)

Query: 9   PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
           P +++  GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 2   PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61

Query: 69  LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
           LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 62  LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121

Query: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
           VPSVSSINRIIRTKVQQPF+ P      T   +PGHT++PS+A  P  S  +D +GS YS
Sbjct: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181

Query: 187 INGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFE 246
           ING+LGI +   +KRK D+   +    + DSQS     RKHLR D F+Q  LE L+  FE
Sbjct: 182 INGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPFE 241

Query: 247 RPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVT 306
           R  YP+ + +  H K EQG  Y LP L   LD+ K++L+ S  P LG N+S  QTYPVV 
Sbjct: 242 RQHYPEAYASPSHTKGEQG-LYPLPLLNSTLDDGKATLTPSNTP-LGRNLSTHQTYPVVA 299

Query: 307 GRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRFSNP 366
           GR+M   TLPGYPPH+P +GQGSY +S +AGMV GSE+SGN Y H  Y++Y+EAWRF N 
Sbjct: 300 GREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYSSYSEAWRFPNS 359

Query: 367 ALLMPP---PGPPLPLLPLPMTATSYRGDHI 394
           +LL  P        P  P P TAT++  DH+
Sbjct: 360 SLLSSPYYYSSTSRPSAP-PTTATAF--DHL 387


>gi|5803117 paired box 8 isoform PAX8A [Homo sapiens]
          Length = 450

 Score =  420 bits (1080), Expect = e-117
 Identities = 240/454 (52%), Positives = 287/454 (63%), Gaps = 73/454 (16%)

Query: 9   PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
           P +++  GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 2   PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61

Query: 69  LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
           LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 62  LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121

Query: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
           VPSVSSINRIIRTKVQQPF+ P      T   +PGHT++PS+A  P  S  +D +GS YS
Sbjct: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181

Query: 187 INGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFE 246
           ING+LGI +   +KRK D+   +    + DSQS     RKHLR D F+Q  LE L+  FE
Sbjct: 182 INGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPFE 241

Query: 247 RPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVV- 305
           R  YP+ + +  H K EQG  Y LP L   LD+ K++L+ S  P LG N+S  QTYPVV 
Sbjct: 242 RQHYPEAYASPSHTKGEQG-LYPLPLLNSTLDDGKATLTPSNTP-LGRNLSTHQTYPVVA 299

Query: 306 -----------TGRDMASTTLP----------------GYPPH----------------- 321
                      T    +S++ P                G PP                  
Sbjct: 300 DPHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVGSGVPPFNAFPHAASVYGQFTGQA 359

Query: 322 --------------VPP----TGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRF 363
                          PP    +GQGSY +S +AGMV GSE+SGN Y H  Y++Y+EAWRF
Sbjct: 360 LLSGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYSSYSEAWRF 419

Query: 364 SNPALLMPP---PGPPLPLLPLPMTATSYRGDHI 394
            N +LL  P        P  P P TAT++  DH+
Sbjct: 420 PNSSLLSSPYYYSSTSRPSAP-PTTATAF--DHL 450


>gi|7524363 paired box 8 isoform PAX8C [Homo sapiens]
          Length = 398

 Score =  384 bits (987), Expect = e-107
 Identities = 216/386 (55%), Positives = 257/386 (66%), Gaps = 18/386 (4%)

Query: 9   PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
           P +++  GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 2   PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61

Query: 69  LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
           LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 62  LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121

Query: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
           VPSVSSINRIIRTKVQQPF+ P      T   +PGHT++PS+A  P  S  +D +GS YS
Sbjct: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181

Query: 187 INGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFE 246
           ING+LGI +   +KRK D+   +    + DSQS     RKHLR D F+Q  LE L+  FE
Sbjct: 182 INGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPFE 241

Query: 247 RPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVT 306
           R  YP+ + +  H K EQG  Y LP L   LD+ K++L+ S  P LG N+S  QTYPVV 
Sbjct: 242 RQHYPEAYASPSHTKGEQG-LYPLPLLNSTLDDGKATLTPSNTP-LGRNLSTHQTYPVVA 299

Query: 307 GRD--MASTTLPGYPPHVP-PTGQGSYPTSTLAGMVPGSEFSG------NPYSHPQYTAY 357
                + S + PG  P +P P       +S       G  + G      +P S P   A 
Sbjct: 300 APPFWICSKSAPGSRPSMPFPMLPPCTGSSRARPSSQGERWWGPRCPDTHPTSPPADRAA 359

Query: 358 -----NEAWRFSNPALLMPPPGPPLP 378
                ++AW      L MP   PP P
Sbjct: 360 MPPLPSQAWWQEVNTLAMPMATPPTP 385


>gi|7524365 paired box 8 isoform PAX8D [Homo sapiens]
          Length = 321

 Score =  355 bits (912), Expect = 3e-98
 Identities = 188/327 (57%), Positives = 225/327 (68%), Gaps = 13/327 (3%)

Query: 9   PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
           P +++  GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 2   PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61

Query: 69  LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
           LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 62  LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121

Query: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
           VPSVSSINRIIRTKVQQPF+ P      T   +PGHT++PS+A  P  S  +D +GS YS
Sbjct: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181

Query: 187 INGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFE 246
           ING+LGI +   +KRK D+   +    + DSQS     RKHLR D F+Q  LE L+  FE
Sbjct: 182 INGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPFE 241

Query: 247 RPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVT 306
           R  YP+ + +  H K EQG  +  P   P           +  P L S            
Sbjct: 242 RQHYPEAYASPSHTKGEQGERWWGPR-CPDTHPTSPPADRAAMPPLPSQ---------AW 291

Query: 307 GRDMASTTLPGYPPHVPPTGQ-GSYPT 332
            +++ +  +P   P  PPT + G+ PT
Sbjct: 292 WQEVNTLAMPMATPPTPPTARPGASPT 318


>gi|7669542 paired box 8 isoform PAX8E [Homo sapiens]
          Length = 287

 Score =  353 bits (907), Expect = 1e-97
 Identities = 178/270 (65%), Positives = 208/270 (77%), Gaps = 3/270 (1%)

Query: 9   PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
           P +++  GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 2   PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61

Query: 69  LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
           LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 62  LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121

Query: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
           VPSVSSINRIIRTKVQQPF+ P      T   +PGHT++PS+A  P  S  +D +GS YS
Sbjct: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181

Query: 187 INGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFE 246
           ING+LGI +   +KRK D+   +    + DSQS     RKHLR D F+Q  LE L+  FE
Sbjct: 182 INGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPFE 241

Query: 247 RPSYPDVFQASEHIKSEQG-NEYSLPALTP 275
           R  YP+ + +  H K EQ  N  ++P  TP
Sbjct: 242 RQHYPEAYASPSHTKGEQEVNTLAMPMATP 271


>gi|189083681 paired box gene 6 isoform a [Homo sapiens]
          Length = 422

 Score =  235 bits (600), Expect = 5e-62
 Identities = 137/257 (53%), Positives = 162/257 (63%), Gaps = 34/257 (13%)

Query: 13  MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRY 72
           M   H GVNQLGGVFVNGRPLPD  RQ+IVELAH G RPCDISR L+VS+GCVSKILGRY
Sbjct: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60

Query: 73  YETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSV 132
           YETGSI+P  IGGSKP+VATP+VV KIA+YKR+ P++FAWEIRDRLL+EG+C ND +PSV
Sbjct: 61  YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120

Query: 133 SSINRIIRTKVQQPFHPTPDG-----------AGTGVTAPG---HTIVPSTASPPVSSAS 178
           SSINR++R    +      DG            G+  T PG    T VP    P      
Sbjct: 121 SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVP--GQPTQDGCQ 178

Query: 179 NDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADT-FTQQQ 237
               G  + N I     SNGE    D D         ++Q  +   RK  R  T FTQ+Q
Sbjct: 179 QQEGGGENTNSI----SSNGE----DSD---------EAQMRLQLKRKLQRNRTSFTQEQ 221

Query: 238 LEALDRVFERPSYPDVF 254
           +EAL++ FER  YPDVF
Sbjct: 222 IEALEKEFERTHYPDVF 238


>gi|4505615 paired box gene 6 isoform a [Homo sapiens]
          Length = 422

 Score =  235 bits (600), Expect = 5e-62
 Identities = 137/257 (53%), Positives = 162/257 (63%), Gaps = 34/257 (13%)

Query: 13  MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRY 72
           M   H GVNQLGGVFVNGRPLPD  RQ+IVELAH G RPCDISR L+VS+GCVSKILGRY
Sbjct: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60

Query: 73  YETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSV 132
           YETGSI+P  IGGSKP+VATP+VV KIA+YKR+ P++FAWEIRDRLL+EG+C ND +PSV
Sbjct: 61  YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120

Query: 133 SSINRIIRTKVQQPFHPTPDG-----------AGTGVTAPG---HTIVPSTASPPVSSAS 178
           SSINR++R    +      DG            G+  T PG    T VP    P      
Sbjct: 121 SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVP--GQPTQDGCQ 178

Query: 179 NDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADT-FTQQQ 237
               G  + N I     SNGE    D D         ++Q  +   RK  R  T FTQ+Q
Sbjct: 179 QQEGGGENTNSI----SSNGE----DSD---------EAQMRLQLKRKLQRNRTSFTQEQ 221

Query: 238 LEALDRVFERPSYPDVF 254
           +EAL++ FER  YPDVF
Sbjct: 222 IEALEKEFERTHYPDVF 238


>gi|4580424 paired box gene 6 isoform b [Homo sapiens]
          Length = 436

 Score =  226 bits (575), Expect = 4e-59
 Identities = 137/271 (50%), Positives = 162/271 (59%), Gaps = 48/271 (17%)

Query: 13  MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLR------------- 59
           M   H GVNQLGGVFVNGRPLPD  RQ+IVELAH G RPCDISR L+             
Sbjct: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQ 60

Query: 60  -VSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRL 118
            VS+GCVSKILGRYYETGSI+P  IGGSKP+VATP+VV KIA+YKR+ P++FAWEIRDRL
Sbjct: 61  NVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 120

Query: 119 LAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDG-----------AGTGVTAPG---HT 164
           L+EG+C ND +PSVSSINR++R    +      DG            G+  T PG    T
Sbjct: 121 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGT 180

Query: 165 IVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSL 224
            VP    P          G  + N I     SNGE    D D         ++Q  +   
Sbjct: 181 SVP--GQPTQDGCQQQEGGGENTNSI----SSNGE----DSD---------EAQMRLQLK 221

Query: 225 RKHLRADT-FTQQQLEALDRVFERPSYPDVF 254
           RK  R  T FTQ+Q+EAL++ FER  YPDVF
Sbjct: 222 RKLQRNRTSFTQEQIEALEKEFERTHYPDVF 252


>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
          Length = 483

 Score =  224 bits (571), Expect = 1e-58
 Identities = 150/382 (39%), Positives = 197/382 (51%), Gaps = 50/382 (13%)

Query: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93

Query: 76  GSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSI 135
           GSI+PG IGGSKPKV TP V  KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSSI
Sbjct: 94  GSIRPGAIGGSKPKVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSI 153

Query: 136 NRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPR 195
           +RI+R+K  +      D                       +  ++    +SI+GIL   R
Sbjct: 154 SRILRSKFGKGEEEEAD------------------LERKEAEESEKKAKHSIDGILS-ER 194

Query: 196 SNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYPDVF 254
           ++  +     D+        DS+  +   RK  R+  TFT +QLE L+R FER  YPD++
Sbjct: 195 ASAPQSDEGSDI--------DSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIY 246

Query: 255 QASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTG-RDMAST 313
              E  +  +  E  +           S+  A    + G+N      + +  G    A  
Sbjct: 247 TREELAQRAKLTEARVQVWF-------SNRRARWRKQAGANQLMAFNHLIPGGFPPTAMP 299

Query: 314 TLPGY--------PPHVP-----PTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEA 360
           TLP Y        P  +P     P+     P       V  S    NP S   Y   +  
Sbjct: 300 TLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTR 359

Query: 361 WRFSN-PALLMPPPGPPLPLLP 381
             FS+     +PP GP  P+ P
Sbjct: 360 HGFSSYTDSFVPPSGPSNPMNP 381


>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
          Length = 403

 Score =  219 bits (559), Expect = 3e-57
 Identities = 150/383 (39%), Positives = 197/383 (51%), Gaps = 51/383 (13%)

Query: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93

Query: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
           GSI+PG IGGSKPK V TP V  KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94  GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153

Query: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
           I+RI+R+K  +      D                       +  ++    +SI+GIL   
Sbjct: 154 ISRILRSKFGKGEEEEAD------------------LERKEAEESEKKAKHSIDGILS-E 194

Query: 195 RSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYPDV 253
           R++  +     D+        DS+  +   RK  R+  TFT +QLE L+R FER  YPD+
Sbjct: 195 RASAPQSDEGSDI--------DSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDI 246

Query: 254 FQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTG-RDMAS 312
           +   E  +  +  E  +           S+  A    + G+N      + +  G    A 
Sbjct: 247 YTREELAQRAKLTEARVQVWF-------SNRRARWRKQAGANQLMAFNHLIPGGFPPTAM 299

Query: 313 TTLPGY--------PPHVP-----PTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNE 359
            TLP Y        P  +P     P+     P       V  S    NP S   Y   + 
Sbjct: 300 PTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPST 359

Query: 360 AWRFSN-PALLMPPPGPPLPLLP 381
              FS+     +PP GP  P+ P
Sbjct: 360 RHGFSSYTDSFVPPSGPSNPMNP 382


>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
          Length = 407

 Score =  219 bits (559), Expect = 3e-57
 Identities = 150/383 (39%), Positives = 197/383 (51%), Gaps = 51/383 (13%)

Query: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93

Query: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
           GSI+PG IGGSKPK V TP V  KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94  GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153

Query: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
           I+RI+R+K  +      D                       +  ++    +SI+GIL   
Sbjct: 154 ISRILRSKFGKGEEEEAD------------------LERKEAEESEKKAKHSIDGILS-E 194

Query: 195 RSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYPDV 253
           R++  +     D+        DS+  +   RK  R+  TFT +QLE L+R FER  YPD+
Sbjct: 195 RASAPQSDEGSDI--------DSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDI 246

Query: 254 FQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTG-RDMAS 312
           +   E  +  +  E  +           S+  A    + G+N      + +  G    A 
Sbjct: 247 YTREELAQRAKLTEARVQVWF-------SNRRARWRKQAGANQLMAFNHLIPGGFPPTAM 299

Query: 313 TTLPGY--------PPHVP-----PTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNE 359
            TLP Y        P  +P     P+     P       V  S    NP S   Y   + 
Sbjct: 300 PTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPST 359

Query: 360 AWRFSN-PALLMPPPGPPLPLLP 381
              FS+     +PP GP  P+ P
Sbjct: 360 RHGFSSYTDSFVPPSGPSNPMNP 382


>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
          Length = 505

 Score =  219 bits (559), Expect = 3e-57
 Identities = 150/383 (39%), Positives = 197/383 (51%), Gaps = 51/383 (13%)

Query: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93

Query: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
           GSI+PG IGGSKPK V TP V  KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94  GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153

Query: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
           I+RI+R+K  +      D                       +  ++    +SI+GIL   
Sbjct: 154 ISRILRSKFGKGEEEEAD------------------LERKEAEESEKKAKHSIDGILS-E 194

Query: 195 RSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYPDV 253
           R++  +     D+        DS+  +   RK  R+  TFT +QLE L+R FER  YPD+
Sbjct: 195 RASAPQSDEGSDI--------DSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDI 246

Query: 254 FQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTG-RDMAS 312
           +   E  +  +  E  +           S+  A    + G+N      + +  G    A 
Sbjct: 247 YTREELAQRAKLTEARVQVWF-------SNRRARWRKQAGANQLMAFNHLIPGGFPPTAM 299

Query: 313 TTLPGY--------PPHVP-----PTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNE 359
            TLP Y        P  +P     P+     P       V  S    NP S   Y   + 
Sbjct: 300 PTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPST 359

Query: 360 AWRFSN-PALLMPPPGPPLPLLP 381
              FS+     +PP GP  P+ P
Sbjct: 360 RHGFSSYTDSFVPPSGPSNPMNP 382


>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
          Length = 484

 Score =  219 bits (559), Expect = 3e-57
 Identities = 150/383 (39%), Positives = 197/383 (51%), Gaps = 51/383 (13%)

Query: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93

Query: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
           GSI+PG IGGSKPK V TP V  KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94  GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153

Query: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
           I+RI+R+K  +      D                       +  ++    +SI+GIL   
Sbjct: 154 ISRILRSKFGKGEEEEAD------------------LERKEAEESEKKAKHSIDGILS-E 194

Query: 195 RSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYPDV 253
           R++  +     D+        DS+  +   RK  R+  TFT +QLE L+R FER  YPD+
Sbjct: 195 RASAPQSDEGSDI--------DSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDI 246

Query: 254 FQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTG-RDMAS 312
           +   E  +  +  E  +           S+  A    + G+N      + +  G    A 
Sbjct: 247 YTREELAQRAKLTEARVQVWF-------SNRRARWRKQAGANQLMAFNHLIPGGFPPTAM 299

Query: 313 TTLPGY--------PPHVP-----PTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNE 359
            TLP Y        P  +P     P+     P       V  S    NP S   Y   + 
Sbjct: 300 PTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPST 359

Query: 360 AWRFSN-PALLMPPPGPPLPLLP 381
              FS+     +PP GP  P+ P
Sbjct: 360 RHGFSSYTDSFVPPSGPSNPMNP 382


>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
          Length = 479

 Score =  219 bits (559), Expect = 3e-57
 Identities = 150/383 (39%), Positives = 197/383 (51%), Gaps = 51/383 (13%)

Query: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93

Query: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
           GSI+PG IGGSKPK V TP V  KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94  GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153

Query: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
           I+RI+R+K  +      D                       +  ++    +SI+GIL   
Sbjct: 154 ISRILRSKFGKGEEEEAD------------------LERKEAEESEKKAKHSIDGILS-E 194

Query: 195 RSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYPDV 253
           R++  +     D+        DS+  +   RK  R+  TFT +QLE L+R FER  YPD+
Sbjct: 195 RASAPQSDEGSDI--------DSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDI 246

Query: 254 FQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTG-RDMAS 312
           +   E  +  +  E  +           S+  A    + G+N      + +  G    A 
Sbjct: 247 YTREELAQRAKLTEARVQVWF-------SNRRARWRKQAGANQLMAFNHLIPGGFPPTAM 299

Query: 313 TTLPGY--------PPHVP-----PTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNE 359
            TLP Y        P  +P     P+     P       V  S    NP S   Y   + 
Sbjct: 300 PTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPST 359

Query: 360 AWRFSN-PALLMPPPGPPLPLLP 381
              FS+     +PP GP  P+ P
Sbjct: 360 RHGFSSYTDSFVPPSGPSNPMNP 382


>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
          Length = 518

 Score =  218 bits (556), Expect = 6e-57
 Identities = 140/340 (41%), Positives = 183/340 (53%), Gaps = 50/340 (14%)

Query: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93

Query: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
           GSI+PG IGGSKP+ VATP V  KI EYKR+NP MF+WEIRDRLL +G CD  TVPSVSS
Sbjct: 94  GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSS 153

Query: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
           I+R++R K  +                                  +    +SI+GILG  
Sbjct: 154 ISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGILG-- 191

Query: 195 RSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYPDV 253
              G +     DV        +S+  +   RK  R+  TFT +QLE L++ FER  YPD+
Sbjct: 192 -DKGNRLDEGSDV--------ESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDI 242

Query: 254 FQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMAST 313
           +   E  +  +  E  +           S+  A    + G+N      + +  G     T
Sbjct: 243 YTREELAQRTKLTEARVQVWF-------SNRRARWRKQAGANQLAAFNHLLPGG--FPPT 293

Query: 314 TLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQ 353
            +P  PP+  P    +YPT+T+      S+  G+    PQ
Sbjct: 294 GMPTLPPYQLP--DSTYPTTTI------SQDGGSTVHRPQ 325


>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
          Length = 520

 Score =  213 bits (543), Expect = 2e-55
 Identities = 140/342 (40%), Positives = 183/342 (53%), Gaps = 52/342 (15%)

Query: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93

Query: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPS--V 132
           GSI+PG IGGSKP+ VATP V  KI EYKR+NP MF+WEIRDRLL +G CD  TVPS  V
Sbjct: 94  GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153

Query: 133 SSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILG 192
           SSI+R++R K  +                                  +    +SI+GILG
Sbjct: 154 SSISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGILG 193

Query: 193 IPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYP 251
                G +     DV        +S+  +   RK  R+  TFT +QLE L++ FER  YP
Sbjct: 194 ---DKGNRLDEGSDV--------ESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYP 242

Query: 252 DVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMA 311
           D++   E  +  +  E  +           S+  A    + G+N      + +  G    
Sbjct: 243 DIYTREELAQRTKLTEARVQVWF-------SNRRARWRKQAGANQLAAFNHLLPGG--FP 293

Query: 312 STTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQ 353
            T +P  PP+  P    +YPT+T+      S+  G+    PQ
Sbjct: 294 PTGMPTLPPYQLP--DSTYPTTTI------SQDGGSTVHRPQ 327


>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
          Length = 505

 Score =  213 bits (543), Expect = 2e-55
 Identities = 140/342 (40%), Positives = 183/342 (53%), Gaps = 52/342 (15%)

Query: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93

Query: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPS--V 132
           GSI+PG IGGSKP+ VATP V  KI EYKR+NP MF+WEIRDRLL +G CD  TVPS  V
Sbjct: 94  GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153

Query: 133 SSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILG 192
           SSI+R++R K  +                                  +    +SI+GILG
Sbjct: 154 SSISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGILG 193

Query: 193 IPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYP 251
                G +     DV        +S+  +   RK  R+  TFT +QLE L++ FER  YP
Sbjct: 194 ---DKGNRLDEGSDV--------ESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYP 242

Query: 252 DVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMA 311
           D++   E  +  +  E  +           S+  A    + G+N      + +  G    
Sbjct: 243 DIYTREELAQRTKLTEARVQVWF-------SNRRARWRKQAGANQLAAFNHLLPGG--FP 293

Query: 312 STTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQ 353
            T +P  PP+  P    +YPT+T+      S+  G+    PQ
Sbjct: 294 PTGMPTLPPYQLP--DSTYPTTTI------SQDGGSTVHRPQ 327


>gi|197276661 paired box 1 [Homo sapiens]
          Length = 534

 Score =  203 bits (516), Expect = 3e-52
 Identities = 156/408 (38%), Positives = 194/408 (47%), Gaps = 59/408 (14%)

Query: 12  AMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGR 71
           AM   +G VNQLGGVFVNGRPLP+ +R RIVELA  G+RPCDISRQLRVSHGCVSKIL R
Sbjct: 94  AMEQTYGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILAR 153

Query: 72  YYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPS 131
           Y ETGSI PG IGGSKP+V TP VV  I +YK+ +P +FAWEIRDRLLA+G+CD   VPS
Sbjct: 154 YNETGSILPGAIGGSKPRVTTPNVVKHIRDYKQGDPGIFAWEIRDRLLADGVCDKYNVPS 213

Query: 132 VSSINRIIRTKVQQPFHPTPDGAG----TGVTAPGHTI----VPSTASPPVSSASNDPVG 183
           VSSI+RI+R K+     P P  A     +  T P + I     PS  SP  +   + P G
Sbjct: 214 VSSISRILRNKIGSLAQPGPYEASKQPPSQPTLPYNHIYQYPYPSPVSPTGAKMGSHP-G 272

Query: 184 SYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQ--QLEAL 241
                G + IPR               S P+  S S +  +R      TF +Q   L   
Sbjct: 273 VPGTAGHVSIPR---------------SWPSAHSVSNILGIR------TFMEQTGALAGS 311

Query: 242 DRVFERPSYPD-------VFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGS 294
           +     P   D        F A+  +     N    PAL     ++K + SAST   +G 
Sbjct: 312 EGTAYSPKMEDWAGVNRTAFPATPAV-----NGLEKPALEA---DIKYTQSASTLSAVGG 363

Query: 295 NVSGTQTYPVVTGRDMASTTLPGY----PPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYS 350
            +     YP      + S    GY    PP  P  G    P      +  G   +   + 
Sbjct: 364 FLPAC-AYPASNQHGVYSAPGGGYLAPGPPWPPAQGPPLAPPGAGVAVHGGELAAAMTFK 422

Query: 351 HPQYTAYNEAWRFSNPALLMPPPGPPLPLLPLPMTATSYRGDHIKLQA 398
           HP           S PA    P  P +     P      RG   + +A
Sbjct: 423 HPSREG-------SLPAPAARPRTPSVAYTDCPSRPRPPRGSSPRTRA 463


>gi|7242167 paired box 9 [Homo sapiens]
          Length = 341

 Score =  199 bits (507), Expect = 3e-51
 Identities = 111/209 (53%), Positives = 131/209 (62%), Gaps = 33/209 (15%)

Query: 13  MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRY 72
           M P  G VNQLGGVFVNGRPLP+ +R RIVELA  G+RPCDISRQLRVSHGCVSKIL RY
Sbjct: 1   MEPAFGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARY 60

Query: 73  YETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSV 132
            ETGSI PG IGGSKP+V TP VV  I  YK+++P +FAWEIRDRLLA+G+CD   VPSV
Sbjct: 61  NETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSV 120

Query: 133 SSINRIIRTKV-----------QQPFHPTPD-----------------GAGTGVTAPGHT 164
           SSI+RI+R K+            +   PTP                   A    T PG  
Sbjct: 121 SSISRILRNKIGNLAQQGHYDSYKQHQPTPQPALPYNHIYSYPSPITAAAAKVPTPPGVP 180

Query: 165 IVPSTASPPVSSASNDPVGSYSINGILGI 193
            +P + + P +  S     S+S+  ILGI
Sbjct: 181 AIPGSVAMPRTWPS-----SHSVTDILGI 204


>gi|7524356 paired box 3 isoform PAX3b [Homo sapiens]
          Length = 206

 Score =  194 bits (493), Expect = 1e-49
 Identities = 93/128 (72%), Positives = 109/128 (85%), Gaps = 1/128 (0%)

Query: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93

Query: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
           GSI+PG IGGSKPK V TP V  KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94  GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153

Query: 135 INRIIRTK 142
           I+RI+R+K
Sbjct: 154 ISRILRSK 161


>gi|6654638 paired box 3 isoform PAX3a [Homo sapiens]
          Length = 215

 Score =  194 bits (493), Expect = 1e-49
 Identities = 93/128 (72%), Positives = 109/128 (85%), Gaps = 1/128 (0%)

Query: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93

Query: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
           GSI+PG IGGSKPK V TP V  KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94  GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153

Query: 135 INRIIRTK 142
           I+RI+R+K
Sbjct: 154 ISRILRSK 161


>gi|170784824 paired box 4 [Homo sapiens]
          Length = 343

 Score =  169 bits (429), Expect = 3e-42
 Identities = 100/233 (42%), Positives = 131/233 (56%), Gaps = 45/233 (19%)

Query: 20  VNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIK 79
           +NQLGG+FVNGRPLP   RQ+IV LA  G+RPCDISR L+VS+GCVSKILGRYY TG ++
Sbjct: 1   MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTGVLE 60

Query: 80  PGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRII 139
           P  IGGSKP++ATP VV +IA+ K + P +FAWEI+ +L AEG+C  D  PSVSSINR++
Sbjct: 61  PKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSVSSINRVL 120

Query: 140 RTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGE 199
           R   +    P      T + +P   + P+  +P   S S  P G++   G          
Sbjct: 121 RALQEDQGLPC-----TRLRSPA-VLAPAVLTP--HSGSETPRGTHPGTG---------- 162

Query: 200 KRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPD 252
                                      H     F+  Q EAL++ F+R  YPD
Sbjct: 163 ---------------------------HRNRTIFSPSQAEALEKEFQRGQYPD 188


>gi|126116581 retina and anterior neural fold homeobox [Homo
           sapiens]
          Length = 346

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 47/165 (28%), Positives = 64/165 (38%), Gaps = 17/165 (10%)

Query: 225 RKHLR-ADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSS 283
           +KH R   TFT  QL  L+R FE+  YPDV+      + E   + +LP +   +      
Sbjct: 134 KKHRRNRTTFTTYQLHELERAFEKSHYPDVYS-----REELAGKVNLPEVRVQVWFQNRR 188

Query: 284 LSASTNPELGSNVSGTQTYPVVT-GRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGS 342
                  +L  +    Q  P+++  R   S TL    P     G G  P     G +P  
Sbjct: 189 AKWRRQEKLEVSSMKLQDSPLLSFSRSPPSATL---SPLGAGPGSGGGPA---GGALPLE 242

Query: 343 EFSGNPYSHPQYTAYNEAWRFSNPALLMP----PPGPPLPLLPLP 383
            + G P      TA      F  PA  +P    PP PP P L  P
Sbjct: 243 SWLGPPLPGGGATALQSLPGFGPPAQSLPASYTPPPPPPPFLNSP 287


>gi|130492454 zinc finger RNA binding protein 2 isoform 1 [Homo
           sapiens]
          Length = 939

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 37/104 (35%), Positives = 44/104 (42%), Gaps = 12/104 (11%)

Query: 294 SNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPY---- 349
           S+    Q  P+V     AST   GY     PT  G  P S+ + +      S NP     
Sbjct: 142 SHAQPPQQAPIVESGQPASTLSSGY---TYPTATGVQPESSASIVTSYPPPSYNPTCTAY 198

Query: 350 ---SHPQYTA--YNEAWRFSNPALLMPPPGPPLPLLPLPMTATS 388
              S+P Y A  Y+ A  F  PA   PPPGPP  L P P  A S
Sbjct: 199 TAPSYPNYDASVYSAASPFYPPAQPPPPPGPPQQLPPPPAPAGS 242


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.134    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,260,670
Number of Sequences: 37866
Number of extensions: 1059392
Number of successful extensions: 5353
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 89
Number of HSP's successfully gapped in prelim test: 181
Number of HSP's that attempted gapping in prelim test: 4805
Number of HSP's gapped (non-prelim): 698
length of query: 408
length of database: 18,247,518
effective HSP length: 105
effective length of query: 303
effective length of database: 14,271,588
effective search space: 4324291164
effective search space used: 4324291164
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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