Guide to the Human Genome
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Search of human proteins with 34878703

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|34878703 paired box protein 2 isoform e [Homo sapiens]
         (431 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|34878703 paired box protein 2 isoform e [Homo sapiens]             888   0.0  
gi|34878716 paired box protein 2 isoform d [Homo sapiens]             825   0.0  
gi|34878699 paired box protein 2 isoform a [Homo sapiens]             808   0.0  
gi|34878701 paired box protein 2 isoform b [Homo sapiens]             745   0.0  
gi|34878709 paired box protein 2 isoform c [Homo sapiens]             680   0.0  
gi|9951920 paired box 5 [Homo sapiens]                                498   e-141
gi|7524361 paired box 8 isoform PAX8B [Homo sapiens]                  464   e-131
gi|5803117 paired box 8 isoform PAX8A [Homo sapiens]                  410   e-114
gi|7524363 paired box 8 isoform PAX8C [Homo sapiens]                  374   e-104
gi|7524365 paired box 8 isoform PAX8D [Homo sapiens]                  345   5e-95
gi|7669542 paired box 8 isoform PAX8E [Homo sapiens]                  343   2e-94
gi|189083681 paired box gene 6 isoform a [Homo sapiens]               229   3e-60
gi|4505615 paired box gene 6 isoform a [Homo sapiens]                 229   3e-60
gi|4580424 paired box gene 6 isoform b [Homo sapiens]                 220   2e-57
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]                215   7e-56
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]                 210   2e-54
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]                 210   2e-54
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]                 210   2e-54
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]                 210   2e-54
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]                  210   2e-54
gi|7524359 paired box 7 isoform 2 [Homo sapiens]                      209   4e-54
gi|4505619 paired box 7 isoform 1 [Homo sapiens]                      204   1e-52
gi|207029223 paired box 7 isoform 3 [Homo sapiens]                    204   1e-52
gi|197276661 paired box 1 [Homo sapiens]                              202   5e-52
gi|7242167 paired box 9 [Homo sapiens]                                199   3e-51
gi|7524356 paired box 3 isoform PAX3b [Homo sapiens]                  194   1e-49
gi|6654638 paired box 3 isoform PAX3a [Homo sapiens]                  194   1e-49
gi|170784824 paired box 4 [Homo sapiens]                              165   6e-41
gi|126116581 retina and anterior neural fold homeobox [Homo sapi...    44   4e-04
gi|130492454 zinc finger RNA binding protein 2 isoform 1 [Homo s...    43   5e-04

>gi|34878703 paired box protein 2 isoform e [Homo sapiens]
          Length = 431

 Score =  888 bits (2294), Expect = 0.0
 Identities = 431/431 (100%), Positives = 431/431 (100%)

Query: 1   MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
           MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
Sbjct: 1   MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60

Query: 61  SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
           SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
Sbjct: 61  SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120

Query: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
           EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
Sbjct: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180

Query: 181 PVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDS 240
           PVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDS
Sbjct: 181 PVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDS 240

Query: 241 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 300
           QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL
Sbjct: 241 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 300

Query: 301 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 360
           DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG
Sbjct: 301 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 360

Query: 361 MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLMPPPGPPLPLLPLPMTATSYRGDHIKLQ 420
           MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLMPPPGPPLPLLPLPMTATSYRGDHIKLQ
Sbjct: 361 MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLMPPPGPPLPLLPLPMTATSYRGDHIKLQ 420

Query: 421 ADSFGLHIVPV 431
           ADSFGLHIVPV
Sbjct: 421 ADSFGLHIVPV 431


>gi|34878716 paired box protein 2 isoform d [Homo sapiens]
          Length = 408

 Score =  825 bits (2132), Expect = 0.0
 Identities = 408/431 (94%), Positives = 408/431 (94%), Gaps = 23/431 (5%)

Query: 1   MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
           MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
Sbjct: 1   MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60

Query: 61  SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
           SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
Sbjct: 61  SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120

Query: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
           EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
Sbjct: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180

Query: 181 PVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDS 240
           PVGSYSINGILGIPRSNGEKRKRDE                       DVSEGSVPNGDS
Sbjct: 181 PVGSYSINGILGIPRSNGEKRKRDE-----------------------DVSEGSVPNGDS 217

Query: 241 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 300
           QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL
Sbjct: 218 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 277

Query: 301 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 360
           DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG
Sbjct: 278 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 337

Query: 361 MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLMPPPGPPLPLLPLPMTATSYRGDHIKLQ 420
           MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLMPPPGPPLPLLPLPMTATSYRGDHIKLQ
Sbjct: 338 MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLMPPPGPPLPLLPLPMTATSYRGDHIKLQ 397

Query: 421 ADSFGLHIVPV 431
           ADSFGLHIVPV
Sbjct: 398 ADSFGLHIVPV 408


>gi|34878699 paired box protein 2 isoform a [Homo sapiens]
          Length = 416

 Score =  808 bits (2086), Expect = 0.0
 Identities = 393/395 (99%), Positives = 393/395 (99%)

Query: 1   MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
           MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
Sbjct: 1   MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60

Query: 61  SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
           SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
Sbjct: 61  SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120

Query: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
           EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
Sbjct: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180

Query: 181 PVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDS 240
           PVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDS
Sbjct: 181 PVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDS 240

Query: 241 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 300
           QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL
Sbjct: 241 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 300

Query: 301 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 360
           DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG
Sbjct: 301 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 360

Query: 361 MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLMPP 395
           MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALL  P
Sbjct: 361 MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSP 395


>gi|34878701 paired box protein 2 isoform b [Homo sapiens]
          Length = 393

 Score =  745 bits (1924), Expect = 0.0
 Identities = 370/395 (93%), Positives = 370/395 (93%), Gaps = 23/395 (5%)

Query: 1   MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
           MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
Sbjct: 1   MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60

Query: 61  SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
           SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
Sbjct: 61  SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120

Query: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
           EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
Sbjct: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180

Query: 181 PVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDS 240
           PVGSYSINGILGIPRSNGEKRKRDE                       DVSEGSVPNGDS
Sbjct: 181 PVGSYSINGILGIPRSNGEKRKRDE-----------------------DVSEGSVPNGDS 217

Query: 241 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 300
           QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL
Sbjct: 218 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 277

Query: 301 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 360
           DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG
Sbjct: 278 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 337

Query: 361 MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLMPP 395
           MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALL  P
Sbjct: 338 MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSP 372


>gi|34878709 paired box protein 2 isoform c [Homo sapiens]
          Length = 396

 Score =  680 bits (1755), Expect = 0.0
 Identities = 340/363 (93%), Positives = 340/363 (93%), Gaps = 23/363 (6%)

Query: 1   MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
           MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
Sbjct: 1   MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60

Query: 61  SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
           SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
Sbjct: 61  SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120

Query: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
           EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
Sbjct: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180

Query: 181 PVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDS 240
           PVGSYSINGILGIPRSNGEKRKRDE                       DVSEGSVPNGDS
Sbjct: 181 PVGSYSINGILGIPRSNGEKRKRDE-----------------------DVSEGSVPNGDS 217

Query: 241 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 300
           QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL
Sbjct: 218 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 277

Query: 301 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 360
           DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG
Sbjct: 278 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 337

Query: 361 MVP 363
           MVP
Sbjct: 338 MVP 340


>gi|9951920 paired box 5 [Homo sapiens]
          Length = 391

 Score =  498 bits (1282), Expect = e-141
 Identities = 260/384 (67%), Positives = 291/384 (75%), Gaps = 34/384 (8%)

Query: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
           GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET
Sbjct: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75

Query: 76  GSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSI 135
           GSIKPGVIGGSKPKVATPKVV+KIAEYKRQNPTMFAWEIRDRLLAE +CDNDTVPSVSSI
Sbjct: 76  GSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSI 135

Query: 136 NRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVG-SYSINGILGI- 193
           NRIIRTKVQQP           V A  H+IV + +   VSS S D  G SYSI+GILGI 
Sbjct: 136 NRIIRTKVQQP-------PNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYSISGILGIT 188

Query: 194 -PRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDSLRKHLR 252
            P ++  KRKRDE                        + E  VPNG S  G D LRK +R
Sbjct: 189 SPSADTNKRKRDE-----------------------GIQESPVPNGHSLPGRDFLRKQMR 225

Query: 253 ADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYS-LPALTPGLDEVKSSLSAST 311
            D FTQQQLE LDRVFER  Y D+F  +E IK EQ  EYS + +L  GLD++K++L++ T
Sbjct: 226 GDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPT 285

Query: 312 NPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNP 371
             ++GS+V G Q+YP+VTGRD+ASTTLPGYPPHVPP GQGSY   TL GMVPGSEFSG+P
Sbjct: 286 PADIGSSVPGPQSYPIVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSP 345

Query: 372 YSHPQYTAYNEAWRFSNPALLMPP 395
           YSHPQY++YN++WRF NP LL  P
Sbjct: 346 YSHPQYSSYNDSWRFPNPGLLGSP 369


>gi|7524361 paired box 8 isoform PAX8B [Homo sapiens]
          Length = 387

 Score =  464 bits (1194), Expect = e-131
 Identities = 246/414 (59%), Positives = 293/414 (70%), Gaps = 33/414 (7%)

Query: 9   PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
           P +++  GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 2   PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61

Query: 69  LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
           LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 62  LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121

Query: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
           VPSVSSINRIIRTKVQQPF+ P      T   +PGHT++PS+A  P  S  +D +GS YS
Sbjct: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181

Query: 187 INGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDS 246
           ING+LGI +   +KRK D+ +                    +D    S+   DSQS    
Sbjct: 182 INGLLGIAQPGSDKRKMDDSD--------------------QDSCRLSI---DSQSSSSG 218

Query: 247 LRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSS 306
            RKHLR D F+Q  LE L+  FER  YP+ + +  H K EQG  Y LP L   LD+ K++
Sbjct: 219 PRKHLRTDAFSQHHLEPLECPFERQHYPEAYASPSHTKGEQG-LYPLPLLNSTLDDGKAT 277

Query: 307 LSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSE 366
           L+ S  P LG N+S  QTYPVV GR+M   TLPGYPPH+P +GQGSY +S +AGMV GSE
Sbjct: 278 LTPSNTP-LGRNLSTHQTYPVVAGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSE 336

Query: 367 FSGNPYSHPQYTAYNEAWRFSNPALLMPP---PGPPLPLLPLPMTATSYRGDHI 417
           +SGN Y H  Y++Y+EAWRF N +LL  P        P  P P TAT++  DH+
Sbjct: 337 YSGNAYGHTPYSSYSEAWRFPNSSLLSSPYYYSSTSRPSAP-PTTATAF--DHL 387


>gi|5803117 paired box 8 isoform PAX8A [Homo sapiens]
          Length = 450

 Score =  410 bits (1053), Expect = e-114
 Identities = 242/477 (50%), Positives = 290/477 (60%), Gaps = 96/477 (20%)

Query: 9   PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
           P +++  GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 2   PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61

Query: 69  LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
           LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 62  LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121

Query: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
           VPSVSSINRIIRTKVQQPF+ P      T   +PGHT++PS+A  P  S  +D +GS YS
Sbjct: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181

Query: 187 INGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDS 246
           ING+LGI +   +KRK D+ +                    +D    S+   DSQS    
Sbjct: 182 INGLLGIAQPGSDKRKMDDSD--------------------QDSCRLSI---DSQSSSSG 218

Query: 247 LRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSS 306
            RKHLR D F+Q  LE L+  FER  YP+ + +  H K EQG  Y LP L   LD+ K++
Sbjct: 219 PRKHLRTDAFSQHHLEPLECPFERQHYPEAYASPSHTKGEQG-LYPLPLLNSTLDDGKAT 277

Query: 307 LSASTNPELGSNVSGTQTYPVV------------TGRDMASTTLP--------------- 339
           L+ S  P LG N+S  QTYPVV            T    +S++ P               
Sbjct: 278 LTPSNTP-LGRNLSTHQTYPVVADPHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVG 336

Query: 340 -GYPPH-------------------------------VPP----TGQGSYPTSTLAGMVP 363
            G PP                                 PP    +GQGSY +S +AGMV 
Sbjct: 337 SGVPPFNAFPHAASVYGQFTGQALLSGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVA 396

Query: 364 GSEFSGNPYSHPQYTAYNEAWRFSNPALLMPP---PGPPLPLLPLPMTATSYRGDHI 417
           GSE+SGN Y H  Y++Y+EAWRF N +LL  P        P  P P TAT++  DH+
Sbjct: 397 GSEYSGNAYGHTPYSSYSEAWRFPNSSLLSSPYYYSSTSRPSAP-PTTATAF--DHL 450


>gi|7524363 paired box 8 isoform PAX8C [Homo sapiens]
          Length = 398

 Score =  374 bits (960), Expect = e-104
 Identities = 218/409 (53%), Positives = 260/409 (63%), Gaps = 41/409 (10%)

Query: 9   PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
           P +++  GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 2   PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61

Query: 69  LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
           LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 62  LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121

Query: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
           VPSVSSINRIIRTKVQQPF+ P      T   +PGHT++PS+A  P  S  +D +GS YS
Sbjct: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181

Query: 187 INGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDS 246
           ING+LGI +   +KRK D+ +                    +D    S+   DSQS    
Sbjct: 182 INGLLGIAQPGSDKRKMDDSD--------------------QDSCRLSI---DSQSSSSG 218

Query: 247 LRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSS 306
            RKHLR D F+Q  LE L+  FER  YP+ + +  H K EQG  Y LP L   LD+ K++
Sbjct: 219 PRKHLRTDAFSQHHLEPLECPFERQHYPEAYASPSHTKGEQG-LYPLPLLNSTLDDGKAT 277

Query: 307 LSASTNPELGSNVSGTQTYPVVTGRD--MASTTLPGYPPHVP-PTGQGSYPTSTLAGMVP 363
           L+ S  P LG N+S  QTYPVV      + S + PG  P +P P       +S       
Sbjct: 278 LTPSNTP-LGRNLSTHQTYPVVAAPPFWICSKSAPGSRPSMPFPMLPPCTGSSRARPSSQ 336

Query: 364 GSEFSG------NPYSHPQYTAY-----NEAWRFSNPALLMPPPGPPLP 401
           G  + G      +P S P   A      ++AW      L MP   PP P
Sbjct: 337 GERWWGPRCPDTHPTSPPADRAAMPPLPSQAWWQEVNTLAMPMATPPTP 385


>gi|7524365 paired box 8 isoform PAX8D [Homo sapiens]
          Length = 321

 Score =  345 bits (885), Expect = 5e-95
 Identities = 190/350 (54%), Positives = 228/350 (65%), Gaps = 36/350 (10%)

Query: 9   PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
           P +++  GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 2   PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61

Query: 69  LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
           LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 62  LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121

Query: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
           VPSVSSINRIIRTKVQQPF+ P      T   +PGHT++PS+A  P  S  +D +GS YS
Sbjct: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181

Query: 187 INGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDS 246
           ING+LGI +   +KRK D+ +                    +D    S+   DSQS    
Sbjct: 182 INGLLGIAQPGSDKRKMDDSD--------------------QDSCRLSI---DSQSSSSG 218

Query: 247 LRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSS 306
            RKHLR D F+Q  LE L+  FER  YP+ + +  H K EQG  +  P   P        
Sbjct: 219 PRKHLRTDAFSQHHLEPLECPFERQHYPEAYASPSHTKGEQGERWWGPR-CPDTHPTSPP 277

Query: 307 LSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQ-GSYPT 355
              +  P L S             +++ +  +P   P  PPT + G+ PT
Sbjct: 278 ADRAAMPPLPSQ---------AWWQEVNTLAMPMATPPTPPTARPGASPT 318


>gi|7669542 paired box 8 isoform PAX8E [Homo sapiens]
          Length = 287

 Score =  343 bits (880), Expect = 2e-94
 Identities = 180/293 (61%), Positives = 211/293 (72%), Gaps = 26/293 (8%)

Query: 9   PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
           P +++  GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 2   PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61

Query: 69  LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
           LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 62  LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121

Query: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
           VPSVSSINRIIRTKVQQPF+ P      T   +PGHT++PS+A  P  S  +D +GS YS
Sbjct: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181

Query: 187 INGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDS 246
           ING+LGI +   +KRK D+ +                    +D    S+   DSQS    
Sbjct: 182 INGLLGIAQPGSDKRKMDDSD--------------------QDSCRLSI---DSQSSSSG 218

Query: 247 LRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQG-NEYSLPALTP 298
            RKHLR D F+Q  LE L+  FER  YP+ + +  H K EQ  N  ++P  TP
Sbjct: 219 PRKHLRTDAFSQHHLEPLECPFERQHYPEAYASPSHTKGEQEVNTLAMPMATP 271


>gi|189083681 paired box gene 6 isoform a [Homo sapiens]
          Length = 422

 Score =  229 bits (585), Expect = 3e-60
 Identities = 134/277 (48%), Positives = 165/277 (59%), Gaps = 51/277 (18%)

Query: 13  MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRY 72
           M   H GVNQLGGVFVNGRPLPD  RQ+IVELAH G RPCDISR L+VS+GCVSKILGRY
Sbjct: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60

Query: 73  YETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSV 132
           YETGSI+P  IGGSKP+VATP+VV KIA+YKR+ P++FAWEIRDRLL+EG+C ND +PSV
Sbjct: 61  YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120

Query: 133 SSINRIIRTKVQQPFHPTPDG-----------AGTGVTAPGHTIVPSTASPPVSSASNDP 181
           SSINR++R    +      DG            G+  T PG    P T+ P         
Sbjct: 121 SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGW--YPGTSVP--------- 169

Query: 182 VGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQ 241
                     G P  +G +++              GGG          +S     + ++Q
Sbjct: 170 ----------GQPTQDGCQQQ-------------EGGGE-----NTNSISSNGEDSDEAQ 201

Query: 242 SGVDSLRKHLRADT-FTQQQLEALDRVFERPSYPDVF 277
             +   RK  R  T FTQ+Q+EAL++ FER  YPDVF
Sbjct: 202 MRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVF 238


>gi|4505615 paired box gene 6 isoform a [Homo sapiens]
          Length = 422

 Score =  229 bits (585), Expect = 3e-60
 Identities = 134/277 (48%), Positives = 165/277 (59%), Gaps = 51/277 (18%)

Query: 13  MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRY 72
           M   H GVNQLGGVFVNGRPLPD  RQ+IVELAH G RPCDISR L+VS+GCVSKILGRY
Sbjct: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60

Query: 73  YETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSV 132
           YETGSI+P  IGGSKP+VATP+VV KIA+YKR+ P++FAWEIRDRLL+EG+C ND +PSV
Sbjct: 61  YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120

Query: 133 SSINRIIRTKVQQPFHPTPDG-----------AGTGVTAPGHTIVPSTASPPVSSASNDP 181
           SSINR++R    +      DG            G+  T PG    P T+ P         
Sbjct: 121 SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGW--YPGTSVP--------- 169

Query: 182 VGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQ 241
                     G P  +G +++              GGG          +S     + ++Q
Sbjct: 170 ----------GQPTQDGCQQQ-------------EGGGE-----NTNSISSNGEDSDEAQ 201

Query: 242 SGVDSLRKHLRADT-FTQQQLEALDRVFERPSYPDVF 277
             +   RK  R  T FTQ+Q+EAL++ FER  YPDVF
Sbjct: 202 MRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVF 238


>gi|4580424 paired box gene 6 isoform b [Homo sapiens]
          Length = 436

 Score =  220 bits (560), Expect = 2e-57
 Identities = 134/291 (46%), Positives = 165/291 (56%), Gaps = 65/291 (22%)

Query: 13  MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLR------------- 59
           M   H GVNQLGGVFVNGRPLPD  RQ+IVELAH G RPCDISR L+             
Sbjct: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQ 60

Query: 60  -VSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRL 118
            VS+GCVSKILGRYYETGSI+P  IGGSKP+VATP+VV KIA+YKR+ P++FAWEIRDRL
Sbjct: 61  NVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 120

Query: 119 LAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDG-----------AGTGVTAPGHTIVP 167
           L+EG+C ND +PSVSSINR++R    +      DG            G+  T PG    P
Sbjct: 121 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGW--YP 178

Query: 168 STASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTL 227
            T+ P                   G P  +G +++              GGG        
Sbjct: 179 GTSVP-------------------GQPTQDGCQQQ-------------EGGGE-----NT 201

Query: 228 RDVSEGSVPNGDSQSGVDSLRKHLRADT-FTQQQLEALDRVFERPSYPDVF 277
             +S     + ++Q  +   RK  R  T FTQ+Q+EAL++ FER  YPDVF
Sbjct: 202 NSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVF 252


>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
          Length = 483

 Score =  215 bits (547), Expect = 7e-56
 Identities = 152/411 (36%), Positives = 194/411 (47%), Gaps = 85/411 (20%)

Query: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93

Query: 76  GSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSI 135
           GSI+PG IGGSKPKV TP V  KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSSI
Sbjct: 94  GSIRPGAIGGSKPKVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSI 153

Query: 136 NRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPR 195
           +RI+R+K  +      D                       +  ++    +SI+GIL    
Sbjct: 154 SRILRSKFGKGEEEEAD------------------LERKEAEESEKKAKHSIDGILS--- 192

Query: 196 SNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDS------LRK 249
                                                 S P  D  S +DS       RK
Sbjct: 193 -----------------------------------ERASAPQSDEGSDIDSEPDLPLKRK 217

Query: 250 HLRA-DTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLS 308
             R+  TFT +QLE L+R FER  YPD++   E  +  +  E  +           S+  
Sbjct: 218 QRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWF-------SNRR 270

Query: 309 ASTNPELGSNVSGTQTYPVVTG-RDMASTTLPGY--------PPHVP-----PTGQGSYP 354
           A    + G+N      + +  G    A  TLP Y        P  +P     P+     P
Sbjct: 271 ARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRP 330

Query: 355 TSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRFSN-PALLMPPPGPPLPLLP 404
                  V  S    NP S   Y   +    FS+     +PP GP  P+ P
Sbjct: 331 QPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNP 381


>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
          Length = 403

 Score =  210 bits (535), Expect = 2e-54
 Identities = 152/412 (36%), Positives = 194/412 (47%), Gaps = 86/412 (20%)

Query: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93

Query: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
           GSI+PG IGGSKPK V TP V  KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94  GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153

Query: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
           I+RI+R+K  +      D                       +  ++    +SI+GIL   
Sbjct: 154 ISRILRSKFGKGEEEEAD------------------LERKEAEESEKKAKHSIDGILS-- 193

Query: 195 RSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDS------LR 248
                                                  S P  D  S +DS       R
Sbjct: 194 ------------------------------------ERASAPQSDEGSDIDSEPDLPLKR 217

Query: 249 KHLRA-DTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSL 307
           K  R+  TFT +QLE L+R FER  YPD++   E  +  +  E  +           S+ 
Sbjct: 218 KQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWF-------SNR 270

Query: 308 SASTNPELGSNVSGTQTYPVVTG-RDMASTTLPGY--------PPHVP-----PTGQGSY 353
            A    + G+N      + +  G    A  TLP Y        P  +P     P+     
Sbjct: 271 RARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHR 330

Query: 354 PTSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRFSN-PALLMPPPGPPLPLLP 404
           P       V  S    NP S   Y   +    FS+     +PP GP  P+ P
Sbjct: 331 PQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNP 382


>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
          Length = 407

 Score =  210 bits (535), Expect = 2e-54
 Identities = 152/412 (36%), Positives = 194/412 (47%), Gaps = 86/412 (20%)

Query: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93

Query: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
           GSI+PG IGGSKPK V TP V  KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94  GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153

Query: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
           I+RI+R+K  +      D                       +  ++    +SI+GIL   
Sbjct: 154 ISRILRSKFGKGEEEEAD------------------LERKEAEESEKKAKHSIDGILS-- 193

Query: 195 RSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDS------LR 248
                                                  S P  D  S +DS       R
Sbjct: 194 ------------------------------------ERASAPQSDEGSDIDSEPDLPLKR 217

Query: 249 KHLRA-DTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSL 307
           K  R+  TFT +QLE L+R FER  YPD++   E  +  +  E  +           S+ 
Sbjct: 218 KQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWF-------SNR 270

Query: 308 SASTNPELGSNVSGTQTYPVVTG-RDMASTTLPGY--------PPHVP-----PTGQGSY 353
            A    + G+N      + +  G    A  TLP Y        P  +P     P+     
Sbjct: 271 RARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHR 330

Query: 354 PTSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRFSN-PALLMPPPGPPLPLLP 404
           P       V  S    NP S   Y   +    FS+     +PP GP  P+ P
Sbjct: 331 PQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNP 382


>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
          Length = 505

 Score =  210 bits (535), Expect = 2e-54
 Identities = 152/412 (36%), Positives = 194/412 (47%), Gaps = 86/412 (20%)

Query: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93

Query: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
           GSI+PG IGGSKPK V TP V  KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94  GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153

Query: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
           I+RI+R+K  +      D                       +  ++    +SI+GIL   
Sbjct: 154 ISRILRSKFGKGEEEEAD------------------LERKEAEESEKKAKHSIDGILS-- 193

Query: 195 RSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDS------LR 248
                                                  S P  D  S +DS       R
Sbjct: 194 ------------------------------------ERASAPQSDEGSDIDSEPDLPLKR 217

Query: 249 KHLRA-DTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSL 307
           K  R+  TFT +QLE L+R FER  YPD++   E  +  +  E  +           S+ 
Sbjct: 218 KQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWF-------SNR 270

Query: 308 SASTNPELGSNVSGTQTYPVVTG-RDMASTTLPGY--------PPHVP-----PTGQGSY 353
            A    + G+N      + +  G    A  TLP Y        P  +P     P+     
Sbjct: 271 RARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHR 330

Query: 354 PTSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRFSN-PALLMPPPGPPLPLLP 404
           P       V  S    NP S   Y   +    FS+     +PP GP  P+ P
Sbjct: 331 PQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNP 382


>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
          Length = 484

 Score =  210 bits (535), Expect = 2e-54
 Identities = 152/412 (36%), Positives = 194/412 (47%), Gaps = 86/412 (20%)

Query: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93

Query: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
           GSI+PG IGGSKPK V TP V  KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94  GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153

Query: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
           I+RI+R+K  +      D                       +  ++    +SI+GIL   
Sbjct: 154 ISRILRSKFGKGEEEEAD------------------LERKEAEESEKKAKHSIDGILS-- 193

Query: 195 RSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDS------LR 248
                                                  S P  D  S +DS       R
Sbjct: 194 ------------------------------------ERASAPQSDEGSDIDSEPDLPLKR 217

Query: 249 KHLRA-DTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSL 307
           K  R+  TFT +QLE L+R FER  YPD++   E  +  +  E  +           S+ 
Sbjct: 218 KQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWF-------SNR 270

Query: 308 SASTNPELGSNVSGTQTYPVVTG-RDMASTTLPGY--------PPHVP-----PTGQGSY 353
            A    + G+N      + +  G    A  TLP Y        P  +P     P+     
Sbjct: 271 RARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHR 330

Query: 354 PTSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRFSN-PALLMPPPGPPLPLLP 404
           P       V  S    NP S   Y   +    FS+     +PP GP  P+ P
Sbjct: 331 PQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNP 382


>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
          Length = 479

 Score =  210 bits (535), Expect = 2e-54
 Identities = 152/412 (36%), Positives = 194/412 (47%), Gaps = 86/412 (20%)

Query: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93

Query: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
           GSI+PG IGGSKPK V TP V  KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94  GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153

Query: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
           I+RI+R+K  +      D                       +  ++    +SI+GIL   
Sbjct: 154 ISRILRSKFGKGEEEEAD------------------LERKEAEESEKKAKHSIDGILS-- 193

Query: 195 RSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDS------LR 248
                                                  S P  D  S +DS       R
Sbjct: 194 ------------------------------------ERASAPQSDEGSDIDSEPDLPLKR 217

Query: 249 KHLRA-DTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSL 307
           K  R+  TFT +QLE L+R FER  YPD++   E  +  +  E  +           S+ 
Sbjct: 218 KQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWF-------SNR 270

Query: 308 SASTNPELGSNVSGTQTYPVVTG-RDMASTTLPGY--------PPHVP-----PTGQGSY 353
            A    + G+N      + +  G    A  TLP Y        P  +P     P+     
Sbjct: 271 RARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHR 330

Query: 354 PTSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRFSN-PALLMPPPGPPLPLLP 404
           P       V  S    NP S   Y   +    FS+     +PP GP  P+ P
Sbjct: 331 PQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNP 382


>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
          Length = 518

 Score =  209 bits (532), Expect = 4e-54
 Identities = 142/363 (39%), Positives = 187/363 (51%), Gaps = 73/363 (20%)

Query: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93

Query: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
           GSI+PG IGGSKP+ VATP V  KI EYKR+NP MF+WEIRDRLL +G CD  TVPSVSS
Sbjct: 94  GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSS 153

Query: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
           I+R++R K  +                                  +    +SI+GIL   
Sbjct: 154 ISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGIL--- 190

Query: 195 RSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDSLRKHLRA- 253
              G+K  R                          + EGS  + +S+  +   RK  R+ 
Sbjct: 191 ---GDKGNR--------------------------LDEGS--DVESEPDLPLKRKQRRSR 219

Query: 254 DTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNP 313
            TFT +QLE L++ FER  YPD++   E  +  +  E  +           S+  A    
Sbjct: 220 TTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWF-------SNRRARWRK 272

Query: 314 ELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYS 373
           + G+N      + +  G     T +P  PP+  P    +YPT+T+      S+  G+   
Sbjct: 273 QAGANQLAAFNHLLPGG--FPPTGMPTLPPYQLP--DSTYPTTTI------SQDGGSTVH 322

Query: 374 HPQ 376
            PQ
Sbjct: 323 RPQ 325


>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
          Length = 520

 Score =  204 bits (519), Expect = 1e-52
 Identities = 142/365 (38%), Positives = 187/365 (51%), Gaps = 75/365 (20%)

Query: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93

Query: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPS--V 132
           GSI+PG IGGSKP+ VATP V  KI EYKR+NP MF+WEIRDRLL +G CD  TVPS  V
Sbjct: 94  GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153

Query: 133 SSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILG 192
           SSI+R++R K  +                                  +    +SI+GIL 
Sbjct: 154 SSISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGIL- 192

Query: 193 IPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDSLRKHLR 252
                G+K  R                          + EGS  + +S+  +   RK  R
Sbjct: 193 -----GDKGNR--------------------------LDEGS--DVESEPDLPLKRKQRR 219

Query: 253 A-DTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSAST 311
           +  TFT +QLE L++ FER  YPD++   E  +  +  E  +           S+  A  
Sbjct: 220 SRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWF-------SNRRARW 272

Query: 312 NPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNP 371
             + G+N      + +  G     T +P  PP+  P    +YPT+T+      S+  G+ 
Sbjct: 273 RKQAGANQLAAFNHLLPGG--FPPTGMPTLPPYQLP--DSTYPTTTI------SQDGGST 322

Query: 372 YSHPQ 376
              PQ
Sbjct: 323 VHRPQ 327


>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
          Length = 505

 Score =  204 bits (519), Expect = 1e-52
 Identities = 142/365 (38%), Positives = 187/365 (51%), Gaps = 75/365 (20%)

Query: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93

Query: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPS--V 132
           GSI+PG IGGSKP+ VATP V  KI EYKR+NP MF+WEIRDRLL +G CD  TVPS  V
Sbjct: 94  GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153

Query: 133 SSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILG 192
           SSI+R++R K  +                                  +    +SI+GIL 
Sbjct: 154 SSISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGIL- 192

Query: 193 IPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDSLRKHLR 252
                G+K  R                          + EGS  + +S+  +   RK  R
Sbjct: 193 -----GDKGNR--------------------------LDEGS--DVESEPDLPLKRKQRR 219

Query: 253 A-DTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSAST 311
           +  TFT +QLE L++ FER  YPD++   E  +  +  E  +           S+  A  
Sbjct: 220 SRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWF-------SNRRARW 272

Query: 312 NPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNP 371
             + G+N      + +  G     T +P  PP+  P    +YPT+T+      S+  G+ 
Sbjct: 273 RKQAGANQLAAFNHLLPGG--FPPTGMPTLPPYQLP--DSTYPTTTI------SQDGGST 322

Query: 372 YSHPQ 376
              PQ
Sbjct: 323 VHRPQ 327


>gi|197276661 paired box 1 [Homo sapiens]
          Length = 534

 Score =  202 bits (514), Expect = 5e-52
 Identities = 112/193 (58%), Positives = 131/193 (67%), Gaps = 9/193 (4%)

Query: 12  AMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGR 71
           AM   +G VNQLGGVFVNGRPLP+ +R RIVELA  G+RPCDISRQLRVSHGCVSKIL R
Sbjct: 94  AMEQTYGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILAR 153

Query: 72  YYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPS 131
           Y ETGSI PG IGGSKP+V TP VV  I +YK+ +P +FAWEIRDRLLA+G+CD   VPS
Sbjct: 154 YNETGSILPGAIGGSKPRVTTPNVVKHIRDYKQGDPGIFAWEIRDRLLADGVCDKYNVPS 213

Query: 132 VSSINRIIRTKVQQPFHPTPDGAG----TGVTAPGHTI----VPSTASPPVSSASNDPVG 183
           VSSI+RI+R K+     P P  A     +  T P + I     PS  SP  +   + P G
Sbjct: 214 VSSISRILRNKIGSLAQPGPYEASKQPPSQPTLPYNHIYQYPYPSPVSPTGAKMGSHP-G 272

Query: 184 SYSINGILGIPRS 196
                G + IPRS
Sbjct: 273 VPGTAGHVSIPRS 285


>gi|7242167 paired box 9 [Homo sapiens]
          Length = 341

 Score =  199 bits (507), Expect = 3e-51
 Identities = 111/209 (53%), Positives = 131/209 (62%), Gaps = 33/209 (15%)

Query: 13  MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRY 72
           M P  G VNQLGGVFVNGRPLP+ +R RIVELA  G+RPCDISRQLRVSHGCVSKIL RY
Sbjct: 1   MEPAFGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARY 60

Query: 73  YETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSV 132
            ETGSI PG IGGSKP+V TP VV  I  YK+++P +FAWEIRDRLLA+G+CD   VPSV
Sbjct: 61  NETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSV 120

Query: 133 SSINRIIRTKV-----------QQPFHPTPD-----------------GAGTGVTAPGHT 164
           SSI+RI+R K+            +   PTP                   A    T PG  
Sbjct: 121 SSISRILRNKIGNLAQQGHYDSYKQHQPTPQPALPYNHIYSYPSPITAAAAKVPTPPGVP 180

Query: 165 IVPSTASPPVSSASNDPVGSYSINGILGI 193
            +P + + P +  S     S+S+  ILGI
Sbjct: 181 AIPGSVAMPRTWPS-----SHSVTDILGI 204


>gi|7524356 paired box 3 isoform PAX3b [Homo sapiens]
          Length = 206

 Score =  194 bits (493), Expect = 1e-49
 Identities = 93/128 (72%), Positives = 109/128 (85%), Gaps = 1/128 (0%)

Query: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93

Query: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
           GSI+PG IGGSKPK V TP V  KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94  GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153

Query: 135 INRIIRTK 142
           I+RI+R+K
Sbjct: 154 ISRILRSK 161


>gi|6654638 paired box 3 isoform PAX3a [Homo sapiens]
          Length = 215

 Score =  194 bits (493), Expect = 1e-49
 Identities = 93/128 (72%), Positives = 109/128 (85%), Gaps = 1/128 (0%)

Query: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93

Query: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
           GSI+PG IGGSKPK V TP V  KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94  GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153

Query: 135 INRIIRTK 142
           I+RI+R+K
Sbjct: 154 ISRILRSK 161


>gi|170784824 paired box 4 [Homo sapiens]
          Length = 343

 Score =  165 bits (418), Expect = 6e-41
 Identities = 89/170 (52%), Positives = 116/170 (68%), Gaps = 8/170 (4%)

Query: 20  VNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIK 79
           +NQLGG+FVNGRPLP   RQ+IV LA  G+RPCDISR L+VS+GCVSKILGRYY TG ++
Sbjct: 1   MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTGVLE 60

Query: 80  PGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRII 139
           P  IGGSKP++ATP VV +IA+ K + P +FAWEI+ +L AEG+C  D  PSVSSINR++
Sbjct: 61  PKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSVSSINRVL 120

Query: 140 RTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSING 189
           R   +    P      T + +P   + P+  +P   S S  P G++   G
Sbjct: 121 RALQEDQGLPC-----TRLRSPA-VLAPAVLTP--HSGSETPRGTHPGTG 162


>gi|126116581 retina and anterior neural fold homeobox [Homo
           sapiens]
          Length = 346

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 47/165 (28%), Positives = 64/165 (38%), Gaps = 17/165 (10%)

Query: 248 RKHLR-ADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSS 306
           +KH R   TFT  QL  L+R FE+  YPDV+      + E   + +LP +   +      
Sbjct: 134 KKHRRNRTTFTTYQLHELERAFEKSHYPDVYS-----REELAGKVNLPEVRVQVWFQNRR 188

Query: 307 LSASTNPELGSNVSGTQTYPVVT-GRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGS 365
                  +L  +    Q  P+++  R   S TL    P     G G  P     G +P  
Sbjct: 189 AKWRRQEKLEVSSMKLQDSPLLSFSRSPPSATL---SPLGAGPGSGGGPA---GGALPLE 242

Query: 366 EFSGNPYSHPQYTAYNEAWRFSNPALLMP----PPGPPLPLLPLP 406
            + G P      TA      F  PA  +P    PP PP P L  P
Sbjct: 243 SWLGPPLPGGGATALQSLPGFGPPAQSLPASYTPPPPPPPFLNSP 287


>gi|130492454 zinc finger RNA binding protein 2 isoform 1 [Homo
           sapiens]
          Length = 939

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 37/104 (35%), Positives = 44/104 (42%), Gaps = 12/104 (11%)

Query: 317 SNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPY---- 372
           S+    Q  P+V     AST   GY     PT  G  P S+ + +      S NP     
Sbjct: 142 SHAQPPQQAPIVESGQPASTLSSGY---TYPTATGVQPESSASIVTSYPPPSYNPTCTAY 198

Query: 373 ---SHPQYTA--YNEAWRFSNPALLMPPPGPPLPLLPLPMTATS 411
              S+P Y A  Y+ A  F  PA   PPPGPP  L P P  A S
Sbjct: 199 TAPSYPNYDASVYSAASPFYPPAQPPPPPGPPQQLPPPPAPAGS 242


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.134    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,365,737
Number of Sequences: 37866
Number of extensions: 1117771
Number of successful extensions: 5287
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 97
Number of HSP's successfully gapped in prelim test: 149
Number of HSP's that attempted gapping in prelim test: 4734
Number of HSP's gapped (non-prelim): 673
length of query: 431
length of database: 18,247,518
effective HSP length: 105
effective length of query: 326
effective length of database: 14,271,588
effective search space: 4652537688
effective search space used: 4652537688
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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