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Search of human proteins with 34878701
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|34878701 paired box protein 2 isoform b [Homo sapiens]
(393 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|34878701 paired box protein 2 isoform b [Homo sapiens] 805 0.0
gi|34878699 paired box protein 2 isoform a [Homo sapiens] 791 0.0
gi|34878716 paired box protein 2 isoform d [Homo sapiens] 758 0.0
gi|34878703 paired box protein 2 isoform e [Homo sapiens] 745 0.0
gi|34878709 paired box protein 2 isoform c [Homo sapiens] 693 0.0
gi|9951920 paired box 5 [Homo sapiens] 544 e-155
gi|7524361 paired box 8 isoform PAX8B [Homo sapiens] 494 e-140
gi|5803117 paired box 8 isoform PAX8A [Homo sapiens] 440 e-124
gi|7524363 paired box 8 isoform PAX8C [Homo sapiens] 383 e-106
gi|7524365 paired box 8 isoform PAX8D [Homo sapiens] 355 3e-98
gi|7669542 paired box 8 isoform PAX8E [Homo sapiens] 353 1e-97
gi|189083681 paired box gene 6 isoform a [Homo sapiens] 235 5e-62
gi|4505615 paired box gene 6 isoform a [Homo sapiens] 235 5e-62
gi|4580424 paired box gene 6 isoform b [Homo sapiens] 226 4e-59
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] 221 1e-57
gi|7524359 paired box 7 isoform 2 [Homo sapiens] 218 6e-57
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] 216 3e-56
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] 216 3e-56
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens] 216 3e-56
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens] 216 3e-56
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens] 216 3e-56
gi|4505619 paired box 7 isoform 1 [Homo sapiens] 213 2e-55
gi|207029223 paired box 7 isoform 3 [Homo sapiens] 213 2e-55
gi|197276661 paired box 1 [Homo sapiens] 202 3e-52
gi|7242167 paired box 9 [Homo sapiens] 199 3e-51
gi|7524356 paired box 3 isoform PAX3b [Homo sapiens] 194 1e-49
gi|6654638 paired box 3 isoform PAX3a [Homo sapiens] 194 1e-49
gi|170784824 paired box 4 [Homo sapiens] 169 3e-42
gi|122937319 even-skipped homeobox 2 [Homo sapiens] 41 0.002
gi|122937484 dorsal root ganglia homeobox [Homo sapiens] 41 0.002
>gi|34878701 paired box protein 2 isoform b [Homo sapiens]
Length = 393
Score = 805 bits (2078), Expect = 0.0
Identities = 393/393 (100%), Positives = 393/393 (100%)
Query: 1 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
Sbjct: 1 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
Query: 61 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
Sbjct: 61 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
Query: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
Sbjct: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
Query: 181 PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA 240
PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA
Sbjct: 181 PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA 240
Query: 241 LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQ 300
LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQ
Sbjct: 241 LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQ 300
Query: 301 TYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEA 360
TYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEA
Sbjct: 301 TYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEA 360
Query: 361 WRFSNPALLSSPYYYSAAPRSAPAAAAAAYDRH 393
WRFSNPALLSSPYYYSAAPRSAPAAAAAAYDRH
Sbjct: 361 WRFSNPALLSSPYYYSAAPRSAPAAAAAAYDRH 393
>gi|34878699 paired box protein 2 isoform a [Homo sapiens]
Length = 416
Score = 791 bits (2044), Expect = 0.0
Identities = 393/416 (94%), Positives = 393/416 (94%), Gaps = 23/416 (5%)
Query: 1 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
Sbjct: 1 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
Query: 61 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
Sbjct: 61 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
Query: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
Sbjct: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
Query: 181 PVGSYSINGILGIPRSNGEKRKRDE-----------------------DVSEGSVPNGDS 217
PVGSYSINGILGIPRSNGEKRKRDE DVSEGSVPNGDS
Sbjct: 181 PVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDS 240
Query: 218 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 277
QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL
Sbjct: 241 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 300
Query: 278 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 337
DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG
Sbjct: 301 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 360
Query: 338 MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSPYYYSAAPRSAPAAAAAAYDRH 393
MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSPYYYSAAPRSAPAAAAAAYDRH
Sbjct: 361 MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSPYYYSAAPRSAPAAAAAAYDRH 416
>gi|34878716 paired box protein 2 isoform d [Homo sapiens]
Length = 408
Score = 758 bits (1958), Expect = 0.0
Identities = 370/372 (99%), Positives = 370/372 (99%)
Query: 1 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
Sbjct: 1 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
Query: 61 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
Sbjct: 61 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
Query: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
Sbjct: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
Query: 181 PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA 240
PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA
Sbjct: 181 PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA 240
Query: 241 LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQ 300
LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQ
Sbjct: 241 LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQ 300
Query: 301 TYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEA 360
TYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEA
Sbjct: 301 TYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEA 360
Query: 361 WRFSNPALLSSP 372
WRFSNPALL P
Sbjct: 361 WRFSNPALLMPP 372
>gi|34878703 paired box protein 2 isoform e [Homo sapiens]
Length = 431
Score = 745 bits (1924), Expect = 0.0
Identities = 370/395 (93%), Positives = 370/395 (93%), Gaps = 23/395 (5%)
Query: 1 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
Sbjct: 1 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
Query: 61 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
Sbjct: 61 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
Query: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
Sbjct: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
Query: 181 PVGSYSINGILGIPRSNGEKRKRDE-----------------------DVSEGSVPNGDS 217
PVGSYSINGILGIPRSNGEKRKRDE DVSEGSVPNGDS
Sbjct: 181 PVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDS 240
Query: 218 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 277
QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL
Sbjct: 241 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 300
Query: 278 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 337
DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG
Sbjct: 301 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 360
Query: 338 MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSP 372
MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALL P
Sbjct: 361 MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLMPP 395
>gi|34878709 paired box protein 2 isoform c [Homo sapiens]
Length = 396
Score = 693 bits (1789), Expect = 0.0
Identities = 340/340 (100%), Positives = 340/340 (100%)
Query: 1 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
Sbjct: 1 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
Query: 61 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
Sbjct: 61 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
Query: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
Sbjct: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
Query: 181 PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA 240
PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA
Sbjct: 181 PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA 240
Query: 241 LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQ 300
LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQ
Sbjct: 241 LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQ 300
Query: 301 TYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVP 340
TYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVP
Sbjct: 301 TYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVP 340
>gi|9951920 paired box 5 [Homo sapiens]
Length = 391
Score = 544 bits (1402), Expect = e-155
Identities = 278/383 (72%), Positives = 310/383 (80%), Gaps = 12/383 (3%)
Query: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET
Sbjct: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
Query: 76 GSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSI 135
GSIKPGVIGGSKPKVATPKVV+KIAEYKRQNPTMFAWEIRDRLLAE +CDNDTVPSVSSI
Sbjct: 76 GSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSI 135
Query: 136 NRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVG-SYSINGILGI- 193
NRIIRTKVQQP V A H+IV + + VSS S D G SYSI+GILGI
Sbjct: 136 NRIIRTKVQQP-------PNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYSISGILGIT 188
Query: 194 -PRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPD 252
P ++ KRKRDE + E VPNG S G D LRK +R D FTQQQLE LDRVFER Y D
Sbjct: 189 SPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSD 248
Query: 253 VFQASEHIKSEQGNEYS-LPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMA 311
+F +E IK EQ EYS + +L GLD++K++L++ T ++GS+V G Q+YP+VTGRD+A
Sbjct: 249 IFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYPIVTGRDLA 308
Query: 312 STTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSS 371
STTLPGYPPHVPP GQGSY TL GMVPGSEFSG+PYSHPQY++YN++WRF NP LL S
Sbjct: 309 STTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRFPNPGLLGS 368
Query: 372 PYYYSAAPR-SAPAAAAAAYDRH 393
PYYYSAA R +AP AAA AYDRH
Sbjct: 369 PYYYSAAARGAAPPAAATAYDRH 391
>gi|7524361 paired box 8 isoform PAX8B [Homo sapiens]
Length = 387
Score = 494 bits (1273), Expect = e-140
Identities = 249/386 (64%), Positives = 294/386 (76%), Gaps = 5/386 (1%)
Query: 9 PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
P +++ GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 2 PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61
Query: 69 LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 62 LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121
Query: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
VPSVSSINRIIRTKVQQPF+ P T +PGHT++PS+A P S +D +GS YS
Sbjct: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181
Query: 187 INGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFE 246
ING+LGI + +KRK D+ + + DSQS RKHLR D F+Q LE L+ FE
Sbjct: 182 INGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPFE 241
Query: 247 RPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVT 306
R YP+ + + H K EQG Y LP L LD+ K++L+ S P LG N+S QTYPVV
Sbjct: 242 RQHYPEAYASPSHTKGEQGL-YPLPLLNSTLDDGKATLTPSNTP-LGRNLSTHQTYPVVA 299
Query: 307 GRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRFSNP 366
GR+M TLPGYPPH+P +GQGSY +S +AGMV GSE+SGN Y H Y++Y+EAWRF N
Sbjct: 300 GREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYSSYSEAWRFPNS 359
Query: 367 ALLSSPYYYSAAPR-SAPAAAAAAYD 391
+LLSSPYYYS+ R SAP A A+D
Sbjct: 360 SLLSSPYYYSSTSRPSAPPTTATAFD 385
>gi|5803117 paired box 8 isoform PAX8A [Homo sapiens]
Length = 450
Score = 440 bits (1132), Expect = e-124
Identities = 245/449 (54%), Positives = 291/449 (64%), Gaps = 68/449 (15%)
Query: 9 PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
P +++ GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 2 PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61
Query: 69 LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 62 LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121
Query: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
VPSVSSINRIIRTKVQQPF+ P T +PGHT++PS+A P S +D +GS YS
Sbjct: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181
Query: 187 INGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFE 246
ING+LGI + +KRK D+ + + DSQS RKHLR D F+Q LE L+ FE
Sbjct: 182 INGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPFE 241
Query: 247 RPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVV- 305
R YP+ + + H K EQG Y LP L LD+ K++L+ S P LG N+S QTYPVV
Sbjct: 242 RQHYPEAYASPSHTKGEQG-LYPLPLLNSTLDDGKATLTPSNTP-LGRNLSTHQTYPVVA 299
Query: 306 -----------TGRDMASTTLP----------------GYPPH----------------- 321
T +S++ P G PP
Sbjct: 300 DPHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVGSGVPPFNAFPHAASVYGQFTGQA 359
Query: 322 --------------VPP----TGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRF 363
PP +GQGSY +S +AGMV GSE+SGN Y H Y++Y+EAWRF
Sbjct: 360 LLSGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYSSYSEAWRF 419
Query: 364 SNPALLSSPYYYSAAPR-SAPAAAAAAYD 391
N +LLSSPYYYS+ R SAP A A+D
Sbjct: 420 PNSSLLSSPYYYSSTSRPSAPPTTATAFD 448
>gi|7524363 paired box 8 isoform PAX8C [Homo sapiens]
Length = 398
Score = 383 bits (983), Expect = e-106
Identities = 200/319 (62%), Positives = 236/319 (73%), Gaps = 6/319 (1%)
Query: 9 PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
P +++ GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 2 PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61
Query: 69 LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 62 LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121
Query: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
VPSVSSINRIIRTKVQQPF+ P T +PGHT++PS+A P S +D +GS YS
Sbjct: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181
Query: 187 INGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFE 246
ING+LGI + +KRK D+ + + DSQS RKHLR D F+Q LE L+ FE
Sbjct: 182 INGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPFE 241
Query: 247 RPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVT 306
R YP+ + + H K EQG Y LP L LD+ K++L+ S P LG N+S QTYPVV
Sbjct: 242 RQHYPEAYASPSHTKGEQG-LYPLPLLNSTLDDGKATLTPSNTP-LGRNLSTHQTYPVVA 299
Query: 307 GRD--MASTTLPGYPPHVP 323
+ S + PG P +P
Sbjct: 300 APPFWICSKSAPGSRPSMP 318
>gi|7524365 paired box 8 isoform PAX8D [Homo sapiens]
Length = 321
Score = 355 bits (912), Expect = 3e-98
Identities = 188/327 (57%), Positives = 225/327 (68%), Gaps = 13/327 (3%)
Query: 9 PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
P +++ GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 2 PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61
Query: 69 LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 62 LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121
Query: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
VPSVSSINRIIRTKVQQPF+ P T +PGHT++PS+A P S +D +GS YS
Sbjct: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181
Query: 187 INGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFE 246
ING+LGI + +KRK D+ + + DSQS RKHLR D F+Q LE L+ FE
Sbjct: 182 INGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPFE 241
Query: 247 RPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVT 306
R YP+ + + H K EQG + P P + P L S
Sbjct: 242 RQHYPEAYASPSHTKGEQGERWWGPR-CPDTHPTSPPADRAAMPPLPSQ---------AW 291
Query: 307 GRDMASTTLPGYPPHVPPTGQ-GSYPT 332
+++ + +P P PPT + G+ PT
Sbjct: 292 WQEVNTLAMPMATPPTPPTARPGASPT 318
>gi|7669542 paired box 8 isoform PAX8E [Homo sapiens]
Length = 287
Score = 353 bits (907), Expect = 1e-97
Identities = 178/270 (65%), Positives = 208/270 (77%), Gaps = 3/270 (1%)
Query: 9 PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
P +++ GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 2 PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61
Query: 69 LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 62 LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121
Query: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
VPSVSSINRIIRTKVQQPF+ P T +PGHT++PS+A P S +D +GS YS
Sbjct: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181
Query: 187 INGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFE 246
ING+LGI + +KRK D+ + + DSQS RKHLR D F+Q LE L+ FE
Sbjct: 182 INGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPFE 241
Query: 247 RPSYPDVFQASEHIKSEQG-NEYSLPALTP 275
R YP+ + + H K EQ N ++P TP
Sbjct: 242 RQHYPEAYASPSHTKGEQEVNTLAMPMATP 271
>gi|189083681 paired box gene 6 isoform a [Homo sapiens]
Length = 422
Score = 235 bits (600), Expect = 5e-62
Identities = 137/257 (53%), Positives = 162/257 (63%), Gaps = 34/257 (13%)
Query: 13 MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRY 72
M H GVNQLGGVFVNGRPLPD RQ+IVELAH G RPCDISR L+VS+GCVSKILGRY
Sbjct: 1 MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60
Query: 73 YETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSV 132
YETGSI+P IGGSKP+VATP+VV KIA+YKR+ P++FAWEIRDRLL+EG+C ND +PSV
Sbjct: 61 YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120
Query: 133 SSINRIIRTKVQQPFHPTPDG-----------AGTGVTAPG---HTIVPSTASPPVSSAS 178
SSINR++R + DG G+ T PG T VP P
Sbjct: 121 SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVP--GQPTQDGCQ 178
Query: 179 NDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADT-FTQQQ 237
G + N I SNGE D D ++Q + RK R T FTQ+Q
Sbjct: 179 QQEGGGENTNSI----SSNGE----DSD---------EAQMRLQLKRKLQRNRTSFTQEQ 221
Query: 238 LEALDRVFERPSYPDVF 254
+EAL++ FER YPDVF
Sbjct: 222 IEALEKEFERTHYPDVF 238
>gi|4505615 paired box gene 6 isoform a [Homo sapiens]
Length = 422
Score = 235 bits (600), Expect = 5e-62
Identities = 137/257 (53%), Positives = 162/257 (63%), Gaps = 34/257 (13%)
Query: 13 MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRY 72
M H GVNQLGGVFVNGRPLPD RQ+IVELAH G RPCDISR L+VS+GCVSKILGRY
Sbjct: 1 MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60
Query: 73 YETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSV 132
YETGSI+P IGGSKP+VATP+VV KIA+YKR+ P++FAWEIRDRLL+EG+C ND +PSV
Sbjct: 61 YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120
Query: 133 SSINRIIRTKVQQPFHPTPDG-----------AGTGVTAPG---HTIVPSTASPPVSSAS 178
SSINR++R + DG G+ T PG T VP P
Sbjct: 121 SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVP--GQPTQDGCQ 178
Query: 179 NDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADT-FTQQQ 237
G + N I SNGE D D ++Q + RK R T FTQ+Q
Sbjct: 179 QQEGGGENTNSI----SSNGE----DSD---------EAQMRLQLKRKLQRNRTSFTQEQ 221
Query: 238 LEALDRVFERPSYPDVF 254
+EAL++ FER YPDVF
Sbjct: 222 IEALEKEFERTHYPDVF 238
>gi|4580424 paired box gene 6 isoform b [Homo sapiens]
Length = 436
Score = 226 bits (575), Expect = 4e-59
Identities = 137/271 (50%), Positives = 162/271 (59%), Gaps = 48/271 (17%)
Query: 13 MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLR------------- 59
M H GVNQLGGVFVNGRPLPD RQ+IVELAH G RPCDISR L+
Sbjct: 1 MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQ 60
Query: 60 -VSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRL 118
VS+GCVSKILGRYYETGSI+P IGGSKP+VATP+VV KIA+YKR+ P++FAWEIRDRL
Sbjct: 61 NVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 120
Query: 119 LAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDG-----------AGTGVTAPG---HT 164
L+EG+C ND +PSVSSINR++R + DG G+ T PG T
Sbjct: 121 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGT 180
Query: 165 IVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSL 224
VP P G + N I SNGE D D ++Q +
Sbjct: 181 SVP--GQPTQDGCQQQEGGGENTNSI----SSNGE----DSD---------EAQMRLQLK 221
Query: 225 RKHLRADT-FTQQQLEALDRVFERPSYPDVF 254
RK R T FTQ+Q+EAL++ FER YPDVF
Sbjct: 222 RKLQRNRTSFTQEQIEALEKEFERTHYPDVF 252
>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
Length = 483
Score = 221 bits (562), Expect = 1e-57
Identities = 121/244 (49%), Positives = 154/244 (63%), Gaps = 28/244 (11%)
Query: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 76 GSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSI 135
GSI+PG IGGSKPKV TP V KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSSI
Sbjct: 94 GSIRPGAIGGSKPKVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSI 153
Query: 136 NRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPR 195
+RI+R+K + D + ++ +SI+GIL R
Sbjct: 154 SRILRSKFGKGEEEEAD------------------LERKEAEESEKKAKHSIDGILS-ER 194
Query: 196 SNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYPDVF 254
++ + D+ DS+ + RK R+ TFT +QLE L+R FER YPD++
Sbjct: 195 ASAPQSDEGSDI--------DSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIY 246
Query: 255 QASE 258
E
Sbjct: 247 TREE 250
>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
Length = 518
Score = 218 bits (556), Expect = 6e-57
Identities = 140/340 (41%), Positives = 183/340 (53%), Gaps = 50/340 (14%)
Query: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
GSI+PG IGGSKP+ VATP V KI EYKR+NP MF+WEIRDRLL +G CD TVPSVSS
Sbjct: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSS 153
Query: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
I+R++R K + + +SI+GILG
Sbjct: 154 ISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGILG-- 191
Query: 195 RSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYPDV 253
G + DV +S+ + RK R+ TFT +QLE L++ FER YPD+
Sbjct: 192 -DKGNRLDEGSDV--------ESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDI 242
Query: 254 FQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMAST 313
+ E + + E + S+ A + G+N + + G T
Sbjct: 243 YTREELAQRTKLTEARVQVWF-------SNRRARWRKQAGANQLAAFNHLLPGG--FPPT 293
Query: 314 TLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQ 353
+P PP+ P +YPT+T+ S+ G+ PQ
Sbjct: 294 GMPTLPPYQLP--DSTYPTTTI------SQDGGSTVHRPQ 325
>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
Length = 403
Score = 216 bits (550), Expect = 3e-56
Identities = 121/245 (49%), Positives = 154/245 (62%), Gaps = 29/245 (11%)
Query: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
GSI+PG IGGSKPK V TP V KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94 GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153
Query: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
I+RI+R+K + D + ++ +SI+GIL
Sbjct: 154 ISRILRSKFGKGEEEEAD------------------LERKEAEESEKKAKHSIDGILS-E 194
Query: 195 RSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYPDV 253
R++ + D+ DS+ + RK R+ TFT +QLE L+R FER YPD+
Sbjct: 195 RASAPQSDEGSDI--------DSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDI 246
Query: 254 FQASE 258
+ E
Sbjct: 247 YTREE 251
>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
Length = 407
Score = 216 bits (550), Expect = 3e-56
Identities = 121/245 (49%), Positives = 154/245 (62%), Gaps = 29/245 (11%)
Query: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
GSI+PG IGGSKPK V TP V KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94 GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153
Query: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
I+RI+R+K + D + ++ +SI+GIL
Sbjct: 154 ISRILRSKFGKGEEEEAD------------------LERKEAEESEKKAKHSIDGILS-E 194
Query: 195 RSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYPDV 253
R++ + D+ DS+ + RK R+ TFT +QLE L+R FER YPD+
Sbjct: 195 RASAPQSDEGSDI--------DSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDI 246
Query: 254 FQASE 258
+ E
Sbjct: 247 YTREE 251
>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
Length = 505
Score = 216 bits (550), Expect = 3e-56
Identities = 121/245 (49%), Positives = 154/245 (62%), Gaps = 29/245 (11%)
Query: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
GSI+PG IGGSKPK V TP V KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94 GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153
Query: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
I+RI+R+K + D + ++ +SI+GIL
Sbjct: 154 ISRILRSKFGKGEEEEAD------------------LERKEAEESEKKAKHSIDGILS-E 194
Query: 195 RSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYPDV 253
R++ + D+ DS+ + RK R+ TFT +QLE L+R FER YPD+
Sbjct: 195 RASAPQSDEGSDI--------DSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDI 246
Query: 254 FQASE 258
+ E
Sbjct: 247 YTREE 251
>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
Length = 484
Score = 216 bits (550), Expect = 3e-56
Identities = 121/245 (49%), Positives = 154/245 (62%), Gaps = 29/245 (11%)
Query: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
GSI+PG IGGSKPK V TP V KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94 GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153
Query: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
I+RI+R+K + D + ++ +SI+GIL
Sbjct: 154 ISRILRSKFGKGEEEEAD------------------LERKEAEESEKKAKHSIDGILS-E 194
Query: 195 RSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYPDV 253
R++ + D+ DS+ + RK R+ TFT +QLE L+R FER YPD+
Sbjct: 195 RASAPQSDEGSDI--------DSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDI 246
Query: 254 FQASE 258
+ E
Sbjct: 247 YTREE 251
>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
Length = 479
Score = 216 bits (550), Expect = 3e-56
Identities = 121/245 (49%), Positives = 154/245 (62%), Gaps = 29/245 (11%)
Query: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
GSI+PG IGGSKPK V TP V KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94 GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153
Query: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
I+RI+R+K + D + ++ +SI+GIL
Sbjct: 154 ISRILRSKFGKGEEEEAD------------------LERKEAEESEKKAKHSIDGILS-E 194
Query: 195 RSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYPDV 253
R++ + D+ DS+ + RK R+ TFT +QLE L+R FER YPD+
Sbjct: 195 RASAPQSDEGSDI--------DSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDI 246
Query: 254 FQASE 258
+ E
Sbjct: 247 YTREE 251
>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
Length = 520
Score = 213 bits (543), Expect = 2e-55
Identities = 140/342 (40%), Positives = 183/342 (53%), Gaps = 52/342 (15%)
Query: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPS--V 132
GSI+PG IGGSKP+ VATP V KI EYKR+NP MF+WEIRDRLL +G CD TVPS V
Sbjct: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
Query: 133 SSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILG 192
SSI+R++R K + + +SI+GILG
Sbjct: 154 SSISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGILG 193
Query: 193 IPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYP 251
G + DV +S+ + RK R+ TFT +QLE L++ FER YP
Sbjct: 194 ---DKGNRLDEGSDV--------ESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYP 242
Query: 252 DVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMA 311
D++ E + + E + S+ A + G+N + + G
Sbjct: 243 DIYTREELAQRTKLTEARVQVWF-------SNRRARWRKQAGANQLAAFNHLLPGG--FP 293
Query: 312 STTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQ 353
T +P PP+ P +YPT+T+ S+ G+ PQ
Sbjct: 294 PTGMPTLPPYQLP--DSTYPTTTI------SQDGGSTVHRPQ 327
>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
Length = 505
Score = 213 bits (543), Expect = 2e-55
Identities = 140/342 (40%), Positives = 183/342 (53%), Gaps = 52/342 (15%)
Query: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPS--V 132
GSI+PG IGGSKP+ VATP V KI EYKR+NP MF+WEIRDRLL +G CD TVPS V
Sbjct: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
Query: 133 SSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILG 192
SSI+R++R K + + +SI+GILG
Sbjct: 154 SSISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGILG 193
Query: 193 IPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYP 251
G + DV +S+ + RK R+ TFT +QLE L++ FER YP
Sbjct: 194 ---DKGNRLDEGSDV--------ESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYP 242
Query: 252 DVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMA 311
D++ E + + E + S+ A + G+N + + G
Sbjct: 243 DIYTREELAQRTKLTEARVQVWF-------SNRRARWRKQAGANQLAAFNHLLPGG--FP 293
Query: 312 STTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQ 353
T +P PP+ P +YPT+T+ S+ G+ PQ
Sbjct: 294 PTGMPTLPPYQLP--DSTYPTTTI------SQDGGSTVHRPQ 327
>gi|197276661 paired box 1 [Homo sapiens]
Length = 534
Score = 202 bits (515), Expect = 3e-52
Identities = 147/362 (40%), Positives = 182/362 (50%), Gaps = 52/362 (14%)
Query: 12 AMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGR 71
AM +G VNQLGGVFVNGRPLP+ +R RIVELA G+RPCDISRQLRVSHGCVSKIL R
Sbjct: 94 AMEQTYGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILAR 153
Query: 72 YYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPS 131
Y ETGSI PG IGGSKP+V TP VV I +YK+ +P +FAWEIRDRLLA+G+CD VPS
Sbjct: 154 YNETGSILPGAIGGSKPRVTTPNVVKHIRDYKQGDPGIFAWEIRDRLLADGVCDKYNVPS 213
Query: 132 VSSINRIIRTKVQQPFHPTPDGAG----TGVTAPGHTI----VPSTASPPVSSASNDPVG 183
VSSI+RI+R K+ P P A + T P + I PS SP + + P G
Sbjct: 214 VSSISRILRNKIGSLAQPGPYEASKQPPSQPTLPYNHIYQYPYPSPVSPTGAKMGSHP-G 272
Query: 184 SYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQ--QLEAL 241
G + IPR S P+ S S + +R TF +Q L
Sbjct: 273 VPGTAGHVSIPR---------------SWPSAHSVSNILGIR------TFMEQTGALAGS 311
Query: 242 DRVFERPSYPD-------VFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGS 294
+ P D F A+ + N PAL ++K + SAST +G
Sbjct: 312 EGTAYSPKMEDWAGVNRTAFPATPAV-----NGLEKPALEA---DIKYTQSASTLSAVGG 363
Query: 295 NVSGTQTYPVVTGRDMASTTLPGY----PPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYS 350
+ YP + S GY PP P G P + G + +
Sbjct: 364 FLPAC-AYPASNQHGVYSAPGGGYLAPGPPWPPAQGPPLAPPGAGVAVHGGELAAAMTFK 422
Query: 351 HP 352
HP
Sbjct: 423 HP 424
>gi|7242167 paired box 9 [Homo sapiens]
Length = 341
Score = 199 bits (507), Expect = 3e-51
Identities = 111/209 (53%), Positives = 131/209 (62%), Gaps = 33/209 (15%)
Query: 13 MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRY 72
M P G VNQLGGVFVNGRPLP+ +R RIVELA G+RPCDISRQLRVSHGCVSKIL RY
Sbjct: 1 MEPAFGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARY 60
Query: 73 YETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSV 132
ETGSI PG IGGSKP+V TP VV I YK+++P +FAWEIRDRLLA+G+CD VPSV
Sbjct: 61 NETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSV 120
Query: 133 SSINRIIRTKV-----------QQPFHPTPD-----------------GAGTGVTAPGHT 164
SSI+RI+R K+ + PTP A T PG
Sbjct: 121 SSISRILRNKIGNLAQQGHYDSYKQHQPTPQPALPYNHIYSYPSPITAAAAKVPTPPGVP 180
Query: 165 IVPSTASPPVSSASNDPVGSYSINGILGI 193
+P + + P + S S+S+ ILGI
Sbjct: 181 AIPGSVAMPRTWPS-----SHSVTDILGI 204
>gi|7524356 paired box 3 isoform PAX3b [Homo sapiens]
Length = 206
Score = 194 bits (493), Expect = 1e-49
Identities = 93/128 (72%), Positives = 109/128 (85%), Gaps = 1/128 (0%)
Query: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
GSI+PG IGGSKPK V TP V KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94 GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153
Query: 135 INRIIRTK 142
I+RI+R+K
Sbjct: 154 ISRILRSK 161
>gi|6654638 paired box 3 isoform PAX3a [Homo sapiens]
Length = 215
Score = 194 bits (493), Expect = 1e-49
Identities = 93/128 (72%), Positives = 109/128 (85%), Gaps = 1/128 (0%)
Query: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
GSI+PG IGGSKPK V TP V KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94 GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153
Query: 135 INRIIRTK 142
I+RI+R+K
Sbjct: 154 ISRILRSK 161
>gi|170784824 paired box 4 [Homo sapiens]
Length = 343
Score = 169 bits (429), Expect = 3e-42
Identities = 100/233 (42%), Positives = 131/233 (56%), Gaps = 45/233 (19%)
Query: 20 VNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIK 79
+NQLGG+FVNGRPLP RQ+IV LA G+RPCDISR L+VS+GCVSKILGRYY TG ++
Sbjct: 1 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTGVLE 60
Query: 80 PGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRII 139
P IGGSKP++ATP VV +IA+ K + P +FAWEI+ +L AEG+C D PSVSSINR++
Sbjct: 61 PKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSVSSINRVL 120
Query: 140 RTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGE 199
R + P T + +P + P+ +P S S P G++ G
Sbjct: 121 RALQEDQGLPC-----TRLRSPA-VLAPAVLTP--HSGSETPRGTHPGTG---------- 162
Query: 200 KRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPD 252
H F+ Q EAL++ F+R YPD
Sbjct: 163 ---------------------------HRNRTIFSPSQAEALEKEFQRGQYPD 188
>gi|122937319 even-skipped homeobox 2 [Homo sapiens]
Length = 476
Score = 40.8 bits (94), Expect = 0.002
Identities = 53/205 (25%), Positives = 81/205 (39%), Gaps = 35/205 (17%)
Query: 208 SEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNE 267
S GS G S SG D +R++ A FT++Q+ L++ F R +Y S + E
Sbjct: 172 SGGSAALGGSGSGADQVRRYRTA--FTREQIARLEKEFYRENY-----VSRPRRCELAAA 224
Query: 268 YSLPALT-------PGLDEVKSSLSAS-TNPELGSNVSGTQTYPVVTGR---DMASTTLP 316
+LP T + + + L+ S +P S + T+ TG S
Sbjct: 225 LNLPETTIKVWFQNRRMKDKRQRLAMSWPHPADPSFYTYMMTHAAATGSLPYPFHSHVPL 284
Query: 317 GYPPHVPPTGQGSYPTSTLAGMVPGSEFS------------GNPYSHPQYTAYNEAWRFS 364
Y PHV T + ++ A S F+ +PYS P+ F
Sbjct: 285 HYYPHVGVTAAAAAAAASGAAAAASSPFATSIRPLDTFRALSHPYSRPELLC-----SFR 339
Query: 365 NPALLSSPYYYSAAPRSAPAAAAAA 389
+P L +P + +A AAAAAA
Sbjct: 340 HPGLYQAPAAAAGLNSAASAAAAAA 364
>gi|122937484 dorsal root ganglia homeobox [Homo sapiens]
Length = 268
Score = 40.8 bits (94), Expect = 0.002
Identities = 21/49 (42%), Positives = 27/49 (55%)
Query: 210 GSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASE 258
G+ +GD G ++ TFT QQLEAL+ VF + YPDVF E
Sbjct: 22 GNHSSGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREE 70
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,723,221
Number of Sequences: 37866
Number of extensions: 919743
Number of successful extensions: 3545
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 83
Number of HSP's successfully gapped in prelim test: 118
Number of HSP's that attempted gapping in prelim test: 3197
Number of HSP's gapped (non-prelim): 436
length of query: 393
length of database: 18,247,518
effective HSP length: 104
effective length of query: 289
effective length of database: 14,309,454
effective search space: 4135432206
effective search space used: 4135432206
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.