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Search of human proteins with 34878699
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|34878699 paired box protein 2 isoform a [Homo sapiens]
(416 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|34878699 paired box protein 2 isoform a [Homo sapiens] 854 0.0
gi|34878703 paired box protein 2 isoform e [Homo sapiens] 808 0.0
gi|34878701 paired box protein 2 isoform b [Homo sapiens] 791 0.0
gi|34878716 paired box protein 2 isoform d [Homo sapiens] 745 0.0
gi|34878709 paired box protein 2 isoform c [Homo sapiens] 680 0.0
gi|9951920 paired box 5 [Homo sapiens] 531 e-151
gi|7524361 paired box 8 isoform PAX8B [Homo sapiens] 484 e-137
gi|5803117 paired box 8 isoform PAX8A [Homo sapiens] 430 e-120
gi|7524363 paired box 8 isoform PAX8C [Homo sapiens] 372 e-103
gi|7524365 paired box 8 isoform PAX8D [Homo sapiens] 345 4e-95
gi|7669542 paired box 8 isoform PAX8E [Homo sapiens] 343 2e-94
gi|189083681 paired box gene 6 isoform a [Homo sapiens] 229 3e-60
gi|4505615 paired box gene 6 isoform a [Homo sapiens] 229 3e-60
gi|4580424 paired box gene 6 isoform b [Homo sapiens] 220 2e-57
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] 211 8e-55
gi|7524359 paired box 7 isoform 2 [Homo sapiens] 209 4e-54
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] 207 2e-53
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] 207 2e-53
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens] 207 2e-53
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens] 207 2e-53
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens] 207 2e-53
gi|4505619 paired box 7 isoform 1 [Homo sapiens] 204 1e-52
gi|207029223 paired box 7 isoform 3 [Homo sapiens] 204 1e-52
gi|197276661 paired box 1 [Homo sapiens] 202 5e-52
gi|7242167 paired box 9 [Homo sapiens] 199 3e-51
gi|7524356 paired box 3 isoform PAX3b [Homo sapiens] 194 1e-49
gi|6654638 paired box 3 isoform PAX3a [Homo sapiens] 194 1e-49
gi|170784824 paired box 4 [Homo sapiens] 165 6e-41
gi|122937319 even-skipped homeobox 2 [Homo sapiens] 42 0.001
gi|122937484 dorsal root ganglia homeobox [Homo sapiens] 41 0.002
>gi|34878699 paired box protein 2 isoform a [Homo sapiens]
Length = 416
Score = 854 bits (2206), Expect = 0.0
Identities = 416/416 (100%), Positives = 416/416 (100%)
Query: 1 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
Sbjct: 1 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
Query: 61 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
Sbjct: 61 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
Query: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
Sbjct: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
Query: 181 PVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDS 240
PVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDS
Sbjct: 181 PVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDS 240
Query: 241 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 300
QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL
Sbjct: 241 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 300
Query: 301 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 360
DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG
Sbjct: 301 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 360
Query: 361 MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSPYYYSAAPRSAPAAAAAAYDRH 416
MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSPYYYSAAPRSAPAAAAAAYDRH
Sbjct: 361 MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSPYYYSAAPRSAPAAAAAAYDRH 416
>gi|34878703 paired box protein 2 isoform e [Homo sapiens]
Length = 431
Score = 808 bits (2086), Expect = 0.0
Identities = 393/395 (99%), Positives = 393/395 (99%)
Query: 1 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
Sbjct: 1 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
Query: 61 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
Sbjct: 61 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
Query: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
Sbjct: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
Query: 181 PVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDS 240
PVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDS
Sbjct: 181 PVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDS 240
Query: 241 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 300
QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL
Sbjct: 241 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 300
Query: 301 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 360
DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG
Sbjct: 301 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 360
Query: 361 MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSP 395
MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALL P
Sbjct: 361 MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLMPP 395
>gi|34878701 paired box protein 2 isoform b [Homo sapiens]
Length = 393
Score = 791 bits (2044), Expect = 0.0
Identities = 393/416 (94%), Positives = 393/416 (94%), Gaps = 23/416 (5%)
Query: 1 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
Sbjct: 1 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
Query: 61 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
Sbjct: 61 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
Query: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
Sbjct: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
Query: 181 PVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDS 240
PVGSYSINGILGIPRSNGEKRKRDE DVSEGSVPNGDS
Sbjct: 181 PVGSYSINGILGIPRSNGEKRKRDE-----------------------DVSEGSVPNGDS 217
Query: 241 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 300
QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL
Sbjct: 218 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 277
Query: 301 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 360
DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG
Sbjct: 278 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 337
Query: 361 MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSPYYYSAAPRSAPAAAAAAYDRH 416
MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSPYYYSAAPRSAPAAAAAAYDRH
Sbjct: 338 MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSPYYYSAAPRSAPAAAAAAYDRH 393
>gi|34878716 paired box protein 2 isoform d [Homo sapiens]
Length = 408
Score = 745 bits (1924), Expect = 0.0
Identities = 370/395 (93%), Positives = 370/395 (93%), Gaps = 23/395 (5%)
Query: 1 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
Sbjct: 1 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
Query: 61 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
Sbjct: 61 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
Query: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
Sbjct: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
Query: 181 PVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDS 240
PVGSYSINGILGIPRSNGEKRKRDE DVSEGSVPNGDS
Sbjct: 181 PVGSYSINGILGIPRSNGEKRKRDE-----------------------DVSEGSVPNGDS 217
Query: 241 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 300
QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL
Sbjct: 218 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 277
Query: 301 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 360
DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG
Sbjct: 278 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 337
Query: 361 MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSP 395
MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALL P
Sbjct: 338 MVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLMPP 372
>gi|34878709 paired box protein 2 isoform c [Homo sapiens]
Length = 396
Score = 680 bits (1755), Expect = 0.0
Identities = 340/363 (93%), Positives = 340/363 (93%), Gaps = 23/363 (6%)
Query: 1 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
Sbjct: 1 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
Query: 61 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
Sbjct: 61 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 120
Query: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
Sbjct: 121 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 180
Query: 181 PVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDS 240
PVGSYSINGILGIPRSNGEKRKRDE DVSEGSVPNGDS
Sbjct: 181 PVGSYSINGILGIPRSNGEKRKRDE-----------------------DVSEGSVPNGDS 217
Query: 241 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 300
QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL
Sbjct: 218 QSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGL 277
Query: 301 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 360
DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG
Sbjct: 278 DEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAG 337
Query: 361 MVP 363
MVP
Sbjct: 338 MVP 340
>gi|9951920 paired box 5 [Homo sapiens]
Length = 391
Score = 531 bits (1368), Expect = e-151
Identities = 278/406 (68%), Positives = 310/406 (76%), Gaps = 35/406 (8%)
Query: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET
Sbjct: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
Query: 76 GSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSI 135
GSIKPGVIGGSKPKVATPKVV+KIAEYKRQNPTMFAWEIRDRLLAE +CDNDTVPSVSSI
Sbjct: 76 GSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSI 135
Query: 136 NRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVG-SYSINGILGI- 193
NRIIRTKVQQP V A H+IV + + VSS S D G SYSI+GILGI
Sbjct: 136 NRIIRTKVQQP-------PNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYSISGILGIT 188
Query: 194 -PRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDSLRKHLR 252
P ++ KRKRDE + E VPNG S G D LRK +R
Sbjct: 189 SPSADTNKRKRDE-----------------------GIQESPVPNGHSLPGRDFLRKQMR 225
Query: 253 ADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYS-LPALTPGLDEVKSSLSAST 311
D FTQQQLE LDRVFER Y D+F +E IK EQ EYS + +L GLD++K++L++ T
Sbjct: 226 GDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPT 285
Query: 312 NPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNP 371
++GS+V G Q+YP+VTGRD+ASTTLPGYPPHVPP GQGSY TL GMVPGSEFSG+P
Sbjct: 286 PADIGSSVPGPQSYPIVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSP 345
Query: 372 YSHPQYTAYNEAWRFSNPALLSSPYYYSAAPR-SAPAAAAAAYDRH 416
YSHPQY++YN++WRF NP LL SPYYYSAA R +AP AAA AYDRH
Sbjct: 346 YSHPQYSSYNDSWRFPNPGLLGSPYYYSAAARGAAPPAAATAYDRH 391
>gi|7524361 paired box 8 isoform PAX8B [Homo sapiens]
Length = 387
Score = 484 bits (1246), Expect = e-137
Identities = 251/409 (61%), Positives = 297/409 (72%), Gaps = 28/409 (6%)
Query: 9 PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
P +++ GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 2 PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61
Query: 69 LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 62 LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121
Query: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
VPSVSSINRIIRTKVQQPF+ P T +PGHT++PS+A P S +D +GS YS
Sbjct: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181
Query: 187 INGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDS 246
ING+LGI + +KRK D+ + +D S+ DSQS
Sbjct: 182 INGLLGIAQPGSDKRKMDDSD--------------------QDSCRLSI---DSQSSSSG 218
Query: 247 LRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSS 306
RKHLR D F+Q LE L+ FER YP+ + + H K EQG Y LP L LD+ K++
Sbjct: 219 PRKHLRTDAFSQHHLEPLECPFERQHYPEAYASPSHTKGEQGL-YPLPLLNSTLDDGKAT 277
Query: 307 LSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSE 366
L+ S P LG N+S QTYPVV GR+M TLPGYPPH+P +GQGSY +S +AGMV GSE
Sbjct: 278 LTPSNTP-LGRNLSTHQTYPVVAGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSE 336
Query: 367 FSGNPYSHPQYTAYNEAWRFSNPALLSSPYYYSAAPR-SAPAAAAAAYD 414
+SGN Y H Y++Y+EAWRF N +LLSSPYYYS+ R SAP A A+D
Sbjct: 337 YSGNAYGHTPYSSYSEAWRFPNSSLLSSPYYYSSTSRPSAPPTTATAFD 385
>gi|5803117 paired box 8 isoform PAX8A [Homo sapiens]
Length = 450
Score = 430 bits (1105), Expect = e-120
Identities = 247/472 (52%), Positives = 294/472 (62%), Gaps = 91/472 (19%)
Query: 9 PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
P +++ GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 2 PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61
Query: 69 LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 62 LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121
Query: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
VPSVSSINRIIRTKVQQPF+ P T +PGHT++PS+A P S +D +GS YS
Sbjct: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181
Query: 187 INGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDS 246
ING+LGI + +KRK D+ + +D S+ DSQS
Sbjct: 182 INGLLGIAQPGSDKRKMDDSD--------------------QDSCRLSI---DSQSSSSG 218
Query: 247 LRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSS 306
RKHLR D F+Q LE L+ FER YP+ + + H K EQG Y LP L LD+ K++
Sbjct: 219 PRKHLRTDAFSQHHLEPLECPFERQHYPEAYASPSHTKGEQG-LYPLPLLNSTLDDGKAT 277
Query: 307 LSASTNPELGSNVSGTQTYPVV------------TGRDMASTTLP--------------- 339
L+ S P LG N+S QTYPVV T +S++ P
Sbjct: 278 LTPSNTP-LGRNLSTHQTYPVVADPHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVG 336
Query: 340 -GYPPH-------------------------------VPP----TGQGSYPTSTLAGMVP 363
G PP PP +GQGSY +S +AGMV
Sbjct: 337 SGVPPFNAFPHAASVYGQFTGQALLSGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVA 396
Query: 364 GSEFSGNPYSHPQYTAYNEAWRFSNPALLSSPYYYSAAPR-SAPAAAAAAYD 414
GSE+SGN Y H Y++Y+EAWRF N +LLSSPYYYS+ R SAP A A+D
Sbjct: 397 GSEYSGNAYGHTPYSSYSEAWRFPNSSLLSSPYYYSSTSRPSAPPTTATAFD 448
>gi|7524363 paired box 8 isoform PAX8C [Homo sapiens]
Length = 398
Score = 372 bits (956), Expect = e-103
Identities = 202/342 (59%), Positives = 239/342 (69%), Gaps = 29/342 (8%)
Query: 9 PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
P +++ GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 2 PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61
Query: 69 LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 62 LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121
Query: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
VPSVSSINRIIRTKVQQPF+ P T +PGHT++PS+A P S +D +GS YS
Sbjct: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181
Query: 187 INGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDS 246
ING+LGI + +KRK D+ + +D S+ DSQS
Sbjct: 182 INGLLGIAQPGSDKRKMDDSD--------------------QDSCRLSI---DSQSSSSG 218
Query: 247 LRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSS 306
RKHLR D F+Q LE L+ FER YP+ + + H K EQG Y LP L LD+ K++
Sbjct: 219 PRKHLRTDAFSQHHLEPLECPFERQHYPEAYASPSHTKGEQG-LYPLPLLNSTLDDGKAT 277
Query: 307 LSASTNPELGSNVSGTQTYPVVTGRD--MASTTLPGYPPHVP 346
L+ S P LG N+S QTYPVV + S + PG P +P
Sbjct: 278 LTPSNTP-LGRNLSTHQTYPVVAAPPFWICSKSAPGSRPSMP 318
>gi|7524365 paired box 8 isoform PAX8D [Homo sapiens]
Length = 321
Score = 345 bits (885), Expect = 4e-95
Identities = 190/350 (54%), Positives = 228/350 (65%), Gaps = 36/350 (10%)
Query: 9 PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
P +++ GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 2 PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61
Query: 69 LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 62 LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121
Query: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
VPSVSSINRIIRTKVQQPF+ P T +PGHT++PS+A P S +D +GS YS
Sbjct: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181
Query: 187 INGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDS 246
ING+LGI + +KRK D+ + +D S+ DSQS
Sbjct: 182 INGLLGIAQPGSDKRKMDDSD--------------------QDSCRLSI---DSQSSSSG 218
Query: 247 LRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSS 306
RKHLR D F+Q LE L+ FER YP+ + + H K EQG + P P
Sbjct: 219 PRKHLRTDAFSQHHLEPLECPFERQHYPEAYASPSHTKGEQGERWWGPR-CPDTHPTSPP 277
Query: 307 LSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQ-GSYPT 355
+ P L S +++ + +P P PPT + G+ PT
Sbjct: 278 ADRAAMPPLPSQ---------AWWQEVNTLAMPMATPPTPPTARPGASPT 318
>gi|7669542 paired box 8 isoform PAX8E [Homo sapiens]
Length = 287
Score = 343 bits (880), Expect = 2e-94
Identities = 180/293 (61%), Positives = 211/293 (72%), Gaps = 26/293 (8%)
Query: 9 PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
P +++ GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 2 PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61
Query: 69 LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 62 LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121
Query: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
VPSVSSINRIIRTKVQQPF+ P T +PGHT++PS+A P S +D +GS YS
Sbjct: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181
Query: 187 INGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDS 246
ING+LGI + +KRK D+ + +D S+ DSQS
Sbjct: 182 INGLLGIAQPGSDKRKMDDSD--------------------QDSCRLSI---DSQSSSSG 218
Query: 247 LRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQG-NEYSLPALTP 298
RKHLR D F+Q LE L+ FER YP+ + + H K EQ N ++P TP
Sbjct: 219 PRKHLRTDAFSQHHLEPLECPFERQHYPEAYASPSHTKGEQEVNTLAMPMATP 271
>gi|189083681 paired box gene 6 isoform a [Homo sapiens]
Length = 422
Score = 229 bits (585), Expect = 3e-60
Identities = 134/277 (48%), Positives = 165/277 (59%), Gaps = 51/277 (18%)
Query: 13 MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRY 72
M H GVNQLGGVFVNGRPLPD RQ+IVELAH G RPCDISR L+VS+GCVSKILGRY
Sbjct: 1 MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60
Query: 73 YETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSV 132
YETGSI+P IGGSKP+VATP+VV KIA+YKR+ P++FAWEIRDRLL+EG+C ND +PSV
Sbjct: 61 YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120
Query: 133 SSINRIIRTKVQQPFHPTPDG-----------AGTGVTAPGHTIVPSTASPPVSSASNDP 181
SSINR++R + DG G+ T PG P T+ P
Sbjct: 121 SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGW--YPGTSVP--------- 169
Query: 182 VGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQ 241
G P +G +++ GGG +S + ++Q
Sbjct: 170 ----------GQPTQDGCQQQ-------------EGGGE-----NTNSISSNGEDSDEAQ 201
Query: 242 SGVDSLRKHLRADT-FTQQQLEALDRVFERPSYPDVF 277
+ RK R T FTQ+Q+EAL++ FER YPDVF
Sbjct: 202 MRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVF 238
>gi|4505615 paired box gene 6 isoform a [Homo sapiens]
Length = 422
Score = 229 bits (585), Expect = 3e-60
Identities = 134/277 (48%), Positives = 165/277 (59%), Gaps = 51/277 (18%)
Query: 13 MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRY 72
M H GVNQLGGVFVNGRPLPD RQ+IVELAH G RPCDISR L+VS+GCVSKILGRY
Sbjct: 1 MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60
Query: 73 YETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSV 132
YETGSI+P IGGSKP+VATP+VV KIA+YKR+ P++FAWEIRDRLL+EG+C ND +PSV
Sbjct: 61 YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120
Query: 133 SSINRIIRTKVQQPFHPTPDG-----------AGTGVTAPGHTIVPSTASPPVSSASNDP 181
SSINR++R + DG G+ T PG P T+ P
Sbjct: 121 SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGW--YPGTSVP--------- 169
Query: 182 VGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQ 241
G P +G +++ GGG +S + ++Q
Sbjct: 170 ----------GQPTQDGCQQQ-------------EGGGE-----NTNSISSNGEDSDEAQ 201
Query: 242 SGVDSLRKHLRADT-FTQQQLEALDRVFERPSYPDVF 277
+ RK R T FTQ+Q+EAL++ FER YPDVF
Sbjct: 202 MRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVF 238
>gi|4580424 paired box gene 6 isoform b [Homo sapiens]
Length = 436
Score = 220 bits (560), Expect = 2e-57
Identities = 134/291 (46%), Positives = 165/291 (56%), Gaps = 65/291 (22%)
Query: 13 MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLR------------- 59
M H GVNQLGGVFVNGRPLPD RQ+IVELAH G RPCDISR L+
Sbjct: 1 MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQ 60
Query: 60 -VSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRL 118
VS+GCVSKILGRYYETGSI+P IGGSKP+VATP+VV KIA+YKR+ P++FAWEIRDRL
Sbjct: 61 NVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 120
Query: 119 LAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDG-----------AGTGVTAPGHTIVP 167
L+EG+C ND +PSVSSINR++R + DG G+ T PG P
Sbjct: 121 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGW--YP 178
Query: 168 STASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTL 227
T+ P G P +G +++ GGG
Sbjct: 179 GTSVP-------------------GQPTQDGCQQQ-------------EGGGE-----NT 201
Query: 228 RDVSEGSVPNGDSQSGVDSLRKHLRADT-FTQQQLEALDRVFERPSYPDVF 277
+S + ++Q + RK R T FTQ+Q+EAL++ FER YPDVF
Sbjct: 202 NSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVF 252
>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
Length = 483
Score = 211 bits (538), Expect = 8e-55
Identities = 123/273 (45%), Positives = 151/273 (55%), Gaps = 63/273 (23%)
Query: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 76 GSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSI 135
GSI+PG IGGSKPKV TP V KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSSI
Sbjct: 94 GSIRPGAIGGSKPKVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSI 153
Query: 136 NRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPR 195
+RI+R+K + D + ++ +SI+GIL
Sbjct: 154 SRILRSKFGKGEEEEAD------------------LERKEAEESEKKAKHSIDGILS--- 192
Query: 196 SNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDS------LRK 249
S P D S +DS RK
Sbjct: 193 -----------------------------------ERASAPQSDEGSDIDSEPDLPLKRK 217
Query: 250 HLRA-DTFTQQQLEALDRVFERPSYPDVFQASE 281
R+ TFT +QLE L+R FER YPD++ E
Sbjct: 218 QRRSRTTFTAEQLEELERAFERTHYPDIYTREE 250
>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
Length = 518
Score = 209 bits (532), Expect = 4e-54
Identities = 142/363 (39%), Positives = 187/363 (51%), Gaps = 73/363 (20%)
Query: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
GSI+PG IGGSKP+ VATP V KI EYKR+NP MF+WEIRDRLL +G CD TVPSVSS
Sbjct: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSS 153
Query: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
I+R++R K + + +SI+GIL
Sbjct: 154 ISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGIL--- 190
Query: 195 RSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDSLRKHLRA- 253
G+K R + EGS + +S+ + RK R+
Sbjct: 191 ---GDKGNR--------------------------LDEGS--DVESEPDLPLKRKQRRSR 219
Query: 254 DTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNP 313
TFT +QLE L++ FER YPD++ E + + E + S+ A
Sbjct: 220 TTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWF-------SNRRARWRK 272
Query: 314 ELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYS 373
+ G+N + + G T +P PP+ P +YPT+T+ S+ G+
Sbjct: 273 QAGANQLAAFNHLLPGG--FPPTGMPTLPPYQLP--DSTYPTTTI------SQDGGSTVH 322
Query: 374 HPQ 376
PQ
Sbjct: 323 RPQ 325
>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
Length = 403
Score = 207 bits (526), Expect = 2e-53
Identities = 123/274 (44%), Positives = 151/274 (55%), Gaps = 64/274 (23%)
Query: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
GSI+PG IGGSKPK V TP V KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94 GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153
Query: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
I+RI+R+K + D + ++ +SI+GIL
Sbjct: 154 ISRILRSKFGKGEEEEAD------------------LERKEAEESEKKAKHSIDGILS-- 193
Query: 195 RSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDS------LR 248
S P D S +DS R
Sbjct: 194 ------------------------------------ERASAPQSDEGSDIDSEPDLPLKR 217
Query: 249 KHLRA-DTFTQQQLEALDRVFERPSYPDVFQASE 281
K R+ TFT +QLE L+R FER YPD++ E
Sbjct: 218 KQRRSRTTFTAEQLEELERAFERTHYPDIYTREE 251
>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
Length = 407
Score = 207 bits (526), Expect = 2e-53
Identities = 123/274 (44%), Positives = 151/274 (55%), Gaps = 64/274 (23%)
Query: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
GSI+PG IGGSKPK V TP V KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94 GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153
Query: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
I+RI+R+K + D + ++ +SI+GIL
Sbjct: 154 ISRILRSKFGKGEEEEAD------------------LERKEAEESEKKAKHSIDGILS-- 193
Query: 195 RSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDS------LR 248
S P D S +DS R
Sbjct: 194 ------------------------------------ERASAPQSDEGSDIDSEPDLPLKR 217
Query: 249 KHLRA-DTFTQQQLEALDRVFERPSYPDVFQASE 281
K R+ TFT +QLE L+R FER YPD++ E
Sbjct: 218 KQRRSRTTFTAEQLEELERAFERTHYPDIYTREE 251
>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
Length = 505
Score = 207 bits (526), Expect = 2e-53
Identities = 123/274 (44%), Positives = 151/274 (55%), Gaps = 64/274 (23%)
Query: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
GSI+PG IGGSKPK V TP V KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94 GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153
Query: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
I+RI+R+K + D + ++ +SI+GIL
Sbjct: 154 ISRILRSKFGKGEEEEAD------------------LERKEAEESEKKAKHSIDGILS-- 193
Query: 195 RSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDS------LR 248
S P D S +DS R
Sbjct: 194 ------------------------------------ERASAPQSDEGSDIDSEPDLPLKR 217
Query: 249 KHLRA-DTFTQQQLEALDRVFERPSYPDVFQASE 281
K R+ TFT +QLE L+R FER YPD++ E
Sbjct: 218 KQRRSRTTFTAEQLEELERAFERTHYPDIYTREE 251
>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
Length = 484
Score = 207 bits (526), Expect = 2e-53
Identities = 123/274 (44%), Positives = 151/274 (55%), Gaps = 64/274 (23%)
Query: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
GSI+PG IGGSKPK V TP V KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94 GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153
Query: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
I+RI+R+K + D + ++ +SI+GIL
Sbjct: 154 ISRILRSKFGKGEEEEAD------------------LERKEAEESEKKAKHSIDGILS-- 193
Query: 195 RSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDS------LR 248
S P D S +DS R
Sbjct: 194 ------------------------------------ERASAPQSDEGSDIDSEPDLPLKR 217
Query: 249 KHLRA-DTFTQQQLEALDRVFERPSYPDVFQASE 281
K R+ TFT +QLE L+R FER YPD++ E
Sbjct: 218 KQRRSRTTFTAEQLEELERAFERTHYPDIYTREE 251
>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
Length = 479
Score = 207 bits (526), Expect = 2e-53
Identities = 123/274 (44%), Positives = 151/274 (55%), Gaps = 64/274 (23%)
Query: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
GSI+PG IGGSKPK V TP V KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94 GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153
Query: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
I+RI+R+K + D + ++ +SI+GIL
Sbjct: 154 ISRILRSKFGKGEEEEAD------------------LERKEAEESEKKAKHSIDGILS-- 193
Query: 195 RSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDS------LR 248
S P D S +DS R
Sbjct: 194 ------------------------------------ERASAPQSDEGSDIDSEPDLPLKR 217
Query: 249 KHLRA-DTFTQQQLEALDRVFERPSYPDVFQASE 281
K R+ TFT +QLE L+R FER YPD++ E
Sbjct: 218 KQRRSRTTFTAEQLEELERAFERTHYPDIYTREE 251
>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
Length = 520
Score = 204 bits (519), Expect = 1e-52
Identities = 142/365 (38%), Positives = 187/365 (51%), Gaps = 75/365 (20%)
Query: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPS--V 132
GSI+PG IGGSKP+ VATP V KI EYKR+NP MF+WEIRDRLL +G CD TVPS V
Sbjct: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
Query: 133 SSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILG 192
SSI+R++R K + + +SI+GIL
Sbjct: 154 SSISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGIL- 192
Query: 193 IPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDSLRKHLR 252
G+K R + EGS + +S+ + RK R
Sbjct: 193 -----GDKGNR--------------------------LDEGS--DVESEPDLPLKRKQRR 219
Query: 253 A-DTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSAST 311
+ TFT +QLE L++ FER YPD++ E + + E + S+ A
Sbjct: 220 SRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWF-------SNRRARW 272
Query: 312 NPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNP 371
+ G+N + + G T +P PP+ P +YPT+T+ S+ G+
Sbjct: 273 RKQAGANQLAAFNHLLPGG--FPPTGMPTLPPYQLP--DSTYPTTTI------SQDGGST 322
Query: 372 YSHPQ 376
PQ
Sbjct: 323 VHRPQ 327
>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
Length = 505
Score = 204 bits (519), Expect = 1e-52
Identities = 142/365 (38%), Positives = 187/365 (51%), Gaps = 75/365 (20%)
Query: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPS--V 132
GSI+PG IGGSKP+ VATP V KI EYKR+NP MF+WEIRDRLL +G CD TVPS V
Sbjct: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
Query: 133 SSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILG 192
SSI+R++R K + + +SI+GIL
Sbjct: 154 SSISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGIL- 192
Query: 193 IPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDSLRKHLR 252
G+K R + EGS + +S+ + RK R
Sbjct: 193 -----GDKGNR--------------------------LDEGS--DVESEPDLPLKRKQRR 219
Query: 253 A-DTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSAST 311
+ TFT +QLE L++ FER YPD++ E + + E + S+ A
Sbjct: 220 SRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWF-------SNRRARW 272
Query: 312 NPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNP 371
+ G+N + + G T +P PP+ P +YPT+T+ S+ G+
Sbjct: 273 RKQAGANQLAAFNHLLPGG--FPPTGMPTLPPYQLP--DSTYPTTTI------SQDGGST 322
Query: 372 YSHPQ 376
PQ
Sbjct: 323 VHRPQ 327
>gi|197276661 paired box 1 [Homo sapiens]
Length = 534
Score = 202 bits (514), Expect = 5e-52
Identities = 112/193 (58%), Positives = 131/193 (67%), Gaps = 9/193 (4%)
Query: 12 AMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGR 71
AM +G VNQLGGVFVNGRPLP+ +R RIVELA G+RPCDISRQLRVSHGCVSKIL R
Sbjct: 94 AMEQTYGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILAR 153
Query: 72 YYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPS 131
Y ETGSI PG IGGSKP+V TP VV I +YK+ +P +FAWEIRDRLLA+G+CD VPS
Sbjct: 154 YNETGSILPGAIGGSKPRVTTPNVVKHIRDYKQGDPGIFAWEIRDRLLADGVCDKYNVPS 213
Query: 132 VSSINRIIRTKVQQPFHPTPDGAG----TGVTAPGHTI----VPSTASPPVSSASNDPVG 183
VSSI+RI+R K+ P P A + T P + I PS SP + + P G
Sbjct: 214 VSSISRILRNKIGSLAQPGPYEASKQPPSQPTLPYNHIYQYPYPSPVSPTGAKMGSHP-G 272
Query: 184 SYSINGILGIPRS 196
G + IPRS
Sbjct: 273 VPGTAGHVSIPRS 285
>gi|7242167 paired box 9 [Homo sapiens]
Length = 341
Score = 199 bits (507), Expect = 3e-51
Identities = 111/209 (53%), Positives = 131/209 (62%), Gaps = 33/209 (15%)
Query: 13 MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRY 72
M P G VNQLGGVFVNGRPLP+ +R RIVELA G+RPCDISRQLRVSHGCVSKIL RY
Sbjct: 1 MEPAFGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARY 60
Query: 73 YETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSV 132
ETGSI PG IGGSKP+V TP VV I YK+++P +FAWEIRDRLLA+G+CD VPSV
Sbjct: 61 NETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSV 120
Query: 133 SSINRIIRTKV-----------QQPFHPTPD-----------------GAGTGVTAPGHT 164
SSI+RI+R K+ + PTP A T PG
Sbjct: 121 SSISRILRNKIGNLAQQGHYDSYKQHQPTPQPALPYNHIYSYPSPITAAAAKVPTPPGVP 180
Query: 165 IVPSTASPPVSSASNDPVGSYSINGILGI 193
+P + + P + S S+S+ ILGI
Sbjct: 181 AIPGSVAMPRTWPS-----SHSVTDILGI 204
>gi|7524356 paired box 3 isoform PAX3b [Homo sapiens]
Length = 206
Score = 194 bits (493), Expect = 1e-49
Identities = 93/128 (72%), Positives = 109/128 (85%), Gaps = 1/128 (0%)
Query: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
GSI+PG IGGSKPK V TP V KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94 GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153
Query: 135 INRIIRTK 142
I+RI+R+K
Sbjct: 154 ISRILRSK 161
>gi|6654638 paired box 3 isoform PAX3a [Homo sapiens]
Length = 215
Score = 194 bits (493), Expect = 1e-49
Identities = 93/128 (72%), Positives = 109/128 (85%), Gaps = 1/128 (0%)
Query: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
GSI+PG IGGSKPK V TP V KI EYKR+NP MF+WEIRD+LL + +CD +TVPSVSS
Sbjct: 94 GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153
Query: 135 INRIIRTK 142
I+RI+R+K
Sbjct: 154 ISRILRSK 161
>gi|170784824 paired box 4 [Homo sapiens]
Length = 343
Score = 165 bits (418), Expect = 6e-41
Identities = 89/170 (52%), Positives = 116/170 (68%), Gaps = 8/170 (4%)
Query: 20 VNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIK 79
+NQLGG+FVNGRPLP RQ+IV LA G+RPCDISR L+VS+GCVSKILGRYY TG ++
Sbjct: 1 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTGVLE 60
Query: 80 PGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRII 139
P IGGSKP++ATP VV +IA+ K + P +FAWEI+ +L AEG+C D PSVSSINR++
Sbjct: 61 PKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSVSSINRVL 120
Query: 140 RTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSING 189
R + P T + +P + P+ +P S S P G++ G
Sbjct: 121 RALQEDQGLPC-----TRLRSPA-VLAPAVLTP--HSGSETPRGTHPGTG 162
>gi|122937319 even-skipped homeobox 2 [Homo sapiens]
Length = 476
Score = 41.6 bits (96), Expect = 0.001
Identities = 68/281 (24%), Positives = 107/281 (38%), Gaps = 47/281 (16%)
Query: 161 PGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRG--- 217
PGH S A+ +S+ VG ++ G+ + K + + Y + G
Sbjct: 102 PGHY---SEAAAEADMSSDVEVGCSALRSPGGL---GAAQLKENNGKGYAESGSAAGTTT 155
Query: 218 ---GGGLHLVWTLRDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYP 274
G GL + S GS G S SG D +R++ A FT++Q+ L++ F R +Y
Sbjct: 156 SASGSGLGSLHGGSGGSGGSAALGGSGSGADQVRRYRTA--FTREQIARLEKEFYRENY- 212
Query: 275 DVFQASEHIKSEQGNEYSLPALT-------PGLDEVKSSLSAS-TNPELGSNVSGTQTYP 326
S + E +LP T + + + L+ S +P S + T+
Sbjct: 213 ----VSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPHPADPSFYTYMMTHA 268
Query: 327 VVTGR---DMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFS------------GNP 371
TG S Y PHV T + ++ A S F+ +P
Sbjct: 269 AATGSLPYPFHSHVPLHYYPHVGVTAAAAAAAASGAAAAASSPFATSIRPLDTFRALSHP 328
Query: 372 YSHPQYTAYNEAWRFSNPALLSSPYYYSAAPRSAPAAAAAA 412
YS P+ F +P L +P + +A AAAAAA
Sbjct: 329 YSRPELLC-----SFRHPGLYQAPAAAAGLNSAASAAAAAA 364
>gi|122937484 dorsal root ganglia homeobox [Homo sapiens]
Length = 268
Score = 40.8 bits (94), Expect = 0.002
Identities = 21/49 (42%), Positives = 27/49 (55%)
Query: 233 GSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASE 281
G+ +GD G ++ TFT QQLEAL+ VF + YPDVF E
Sbjct: 22 GNHSSGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREE 70
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.132 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,828,288
Number of Sequences: 37866
Number of extensions: 978122
Number of successful extensions: 3479
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 91
Number of HSP's successfully gapped in prelim test: 86
Number of HSP's that attempted gapping in prelim test: 3127
Number of HSP's gapped (non-prelim): 404
length of query: 416
length of database: 18,247,518
effective HSP length: 105
effective length of query: 311
effective length of database: 14,271,588
effective search space: 4438463868
effective search space used: 4438463868
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.