Guide to the Human Genome
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Search of human proteins with 34577059

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|34577059 adipose differentiation-related protein [Homo
sapiens]
         (437 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|34577059 adipose differentiation-related protein [Homo sapiens]    848   0.0  
gi|20127486 mannose 6 phosphate receptor binding protein 1 [Homo...   351   6e-97
gi|116292172 lipid storage droplet protein 5 [Homo sapiens]           229   5e-60
gi|223718196 perilipin [Homo sapiens]                                 130   2e-30
gi|223718203 perilipin [Homo sapiens]                                 130   2e-30
gi|122937195 plasma membrane associated protein, S3-12 [Homo sap...    82   7e-16
gi|10440566 leucine zipper, putative tumor suppressor 1 [Homo sa...    37   0.035
gi|122937396 coiled-coil domain containing 150 [Homo sapiens]          37   0.046
gi|114155142 nuclear pore complex-associated protein TPR [Homo s...    35   0.10 
gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]       35   0.18 
gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]       35   0.18 
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]                   34   0.23 
gi|4826934 protein phosphatase 4, regulatory subunit 1 isoform b...    34   0.23 
gi|108936953 protein phosphatase 4, regulatory subunit 1 isoform...    34   0.23 
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         34   0.30 
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]         34   0.30 
gi|53729363 leucine rich repeat and sterile alpha motif containi...    33   0.39 
gi|53729361 leucine rich repeat and sterile alpha motif containi...    33   0.39 
gi|53729359 leucine rich repeat and sterile alpha motif containi...    33   0.39 
gi|24308303 SH3-binding domain protein 5-like [Homo sapiens]           33   0.51 
gi|118498356 kinectin 1 isoform a [Homo sapiens]                       32   0.87 
gi|118498368 kinectin 1 isoform c [Homo sapiens]                       32   0.87 
gi|33620775 kinectin 1 isoform a [Homo sapiens]                        32   0.87 
gi|64085252 hypothetical protein LOC145508 [Homo sapiens]              32   1.1  
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     32   1.5  
gi|118498362 kinectin 1 isoform b [Homo sapiens]                       32   1.5  
gi|25777650 small conductance calcium-activated potassium channe...    32   1.5  
gi|116805330 small conductance calcium-activated potassium chann...    32   1.5  
gi|89886447 nitric oxide synthase trafficker isoform 2 [Homo sap...    32   1.5  
gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens]     32   1.5  

>gi|34577059 adipose differentiation-related protein [Homo sapiens]
          Length = 437

 Score =  848 bits (2190), Expect = 0.0
 Identities = 437/437 (100%), Positives = 437/437 (100%)

Query: 1   MASVAVDPQPSVVTRVVNLPLVSSTYDLMSSAYLSTKDQYPYLKSVCEMAENGVKTITSV 60
           MASVAVDPQPSVVTRVVNLPLVSSTYDLMSSAYLSTKDQYPYLKSVCEMAENGVKTITSV
Sbjct: 1   MASVAVDPQPSVVTRVVNLPLVSSTYDLMSSAYLSTKDQYPYLKSVCEMAENGVKTITSV 60

Query: 61  AMTSALPIIQKLEPQIAVANTYACKGLDRIEERLPILNQPSTQIVANAKGAVTGAKDAVT 120
           AMTSALPIIQKLEPQIAVANTYACKGLDRIEERLPILNQPSTQIVANAKGAVTGAKDAVT
Sbjct: 61  AMTSALPIIQKLEPQIAVANTYACKGLDRIEERLPILNQPSTQIVANAKGAVTGAKDAVT 120

Query: 121 TTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSRMMQLVSSGVENAL 180
           TTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSRMMQLVSSGVENAL
Sbjct: 121 TTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSRMMQLVSSGVENAL 180

Query: 181 TKSELLVEQYLPLTEEELEKEAKKVEGFDLVQKPSYYVRLGSLSTKLHSRAYQQALSRVK 240
           TKSELLVEQYLPLTEEELEKEAKKVEGFDLVQKPSYYVRLGSLSTKLHSRAYQQALSRVK
Sbjct: 181 TKSELLVEQYLPLTEEELEKEAKKVEGFDLVQKPSYYVRLGSLSTKLHSRAYQQALSRVK 240

Query: 241 EAKQKSQQTISQLHSTVHLIEFARKNVYSANQKIQDAQDKLYLSWVEWKRSIGYDDTDES 300
           EAKQKSQQTISQLHSTVHLIEFARKNVYSANQKIQDAQDKLYLSWVEWKRSIGYDDTDES
Sbjct: 241 EAKQKSQQTISQLHSTVHLIEFARKNVYSANQKIQDAQDKLYLSWVEWKRSIGYDDTDES 300

Query: 301 HCAEHIESRTLAIARNLTQQLQTTCHTLLSNIQGVPQNIQDQAKHMGVMAGDIYSVFRNA 360
           HCAEHIESRTLAIARNLTQQLQTTCHTLLSNIQGVPQNIQDQAKHMGVMAGDIYSVFRNA
Sbjct: 301 HCAEHIESRTLAIARNLTQQLQTTCHTLLSNIQGVPQNIQDQAKHMGVMAGDIYSVFRNA 360

Query: 361 ASFKEVSDSLLTSSKGQLQKMKESLDDVMDYLVNNTPLNWLVGPFYPQLTESQNAQDQGA 420
           ASFKEVSDSLLTSSKGQLQKMKESLDDVMDYLVNNTPLNWLVGPFYPQLTESQNAQDQGA
Sbjct: 361 ASFKEVSDSLLTSSKGQLQKMKESLDDVMDYLVNNTPLNWLVGPFYPQLTESQNAQDQGA 420

Query: 421 EMDKSSQETQRSEHKTH 437
           EMDKSSQETQRSEHKTH
Sbjct: 421 EMDKSSQETQRSEHKTH 437


>gi|20127486 mannose 6 phosphate receptor binding protein 1 [Homo
           sapiens]
          Length = 434

 Score =  351 bits (901), Expect = 6e-97
 Identities = 175/409 (42%), Positives = 275/409 (67%), Gaps = 9/409 (2%)

Query: 9   QPSVVTRVVNLPLVSSTYDLMSSAYLSTKDQYPYLKSVCEMAENGVKTITSVAMTSALPI 68
           QPSVV RV ++PL+SST D++S+AY STK+ YP++K+VC+ AE GV+T+T+ A++ A PI
Sbjct: 22  QPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVCDAAEKGVRTLTAAAVSGAQPI 81

Query: 69  IQKLEPQIAVANTYACKGLDRIEERLPILNQPSTQIVANAKGAVTGAKDAVTTTVTGAKD 128
           + KLEPQIA A+ YA +GLD++EE LPIL QP+ +++A+ K  V+         V+ AKD
Sbjct: 82  LSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLADTKELVSSKVSGAQEMVSSAKD 141

Query: 129 SVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSRMMQLVSSGVENALTKSELLVE 188
           +VA+ ++  +D T+GAV   V+KTKSVV+G + +V+GSR+ Q+V SGV+  L KSE   +
Sbjct: 142 TVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGVDTVLGKSEEWAD 201

Query: 189 QYLPLTEEELEKEAKKVEGFDLV------QKPSYYVRLGSLSTKLHSRAYQQALSRVKEA 242
            +LPLT+ EL + A  ++GFD+       Q+ SY+VRLGSLS +L   AY+ +L +++  
Sbjct: 202 NHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLGSLSERLRQHAYEHSLGKLRAT 261

Query: 243 KQKSQQTISQLHSTVHLIEFARKNVYSANQKIQDAQDKLYLSWVEWKRSIGYDDTDESHC 302
           KQ++Q+ + QL   + L+E  ++ V   +QK+ + Q+KL+  W+ W +        E   
Sbjct: 262 KQRAQEALLQLSQALSLMETVKQGV---DQKLVEGQEKLHQMWLSWNQKQLQGPEKEPPK 318

Query: 303 AEHIESRTLAIARNLTQQLQTTCHTLLSNIQGVPQNIQDQAKHMGVMAGDIYSVFRNAAS 362
            E +ESR L + R++ QQLQ TC +L S+IQG+P N++DQ +       D+ + F +  S
Sbjct: 319 PEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQQARRQVEDLQATFSSIHS 378

Query: 363 FKEVSDSLLTSSKGQLQKMKESLDDVMDYLVNNTPLNWLVGPFYPQLTE 411
           F+++S S+L  S+ ++   +E+LD +++Y+  NTP+ WLVGPF P +TE
Sbjct: 379 FQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGPFAPGITE 427


>gi|116292172 lipid storage droplet protein 5 [Homo sapiens]
          Length = 463

 Score =  229 bits (583), Expect = 5e-60
 Identities = 142/416 (34%), Positives = 222/416 (53%), Gaps = 49/416 (11%)

Query: 2   ASVAVDPQPSVVTRVVNLPLVSSTYDLMSSAYLSTKDQYPYLKSVCEMAENGVKTITSVA 61
           +SV    Q +VV RVV LPLV +T   +   Y + KD++P L S C +AEN V  +T+ A
Sbjct: 12  SSVWEQDQQNVVQRVVALPLVRATCTAVCDVYSAAKDRHPLLGSACRLAENCVCGLTTRA 71

Query: 62  MTSALPIIQKLEPQIAVANTYACKGLDRIEERLPILNQPSTQIVANAKGAVTGAKDAVTT 121
           +  A P+++ L+PQ+A  N+ AC+GLD++EE+LP L QPS                   T
Sbjct: 72  LDHAQPLLEHLQPQLATMNSLACRGLDKLEEKLPFLQQPS------------------ET 113

Query: 122 TVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSRMMQLVSSGVENALT 181
            VT AKD VAS++TGV+D  +     SVE  +S                 VS  V+  L 
Sbjct: 114 VVTSAKDVVASSVTGVVDLARRGRRWSVELKRS-----------------VSHAVDVVLE 156

Query: 182 KSELLVEQYLPLTEEELEKEAKKVEG------FDLVQKPSYYVRLGSLSTKLHSRAYQQA 235
           KSE LV+ +LP+TEEEL   A + EG       D  ++  Y+VRLGSLS ++   AY+ +
Sbjct: 157 KSEELVDHFLPMTEEELAALAAEAEGPEVGSVEDQRRQQGYFVRLGSLSARIRHLAYEHS 216

Query: 236 LSRVKEAKQKSQQTISQLHSTVHLIEFARKNVYSANQKIQDAQDKLYLSWVEWKRSIGYD 295
           + +++++K ++Q T++QL  T+ LI+  +  V            K++  W EW +     
Sbjct: 217 VGKLRQSKHRAQDTLAQLQETLELIDHMQCGV---TPTAPACPGKVHELWGEWGQR---- 269

Query: 296 DTDESHCAEHIESRTLAIARNLTQQLQTTCHTLLSNIQGVPQNIQDQAKHMGVMAGDIYS 355
              ES      E  TL ++R+LTQ+LQ T   L S+++G+P   Q++   +      + +
Sbjct: 270 -PPESRRRSQAELETLVLSRSLTQELQGTVEALESSVRGLPAGAQEKVAEVRRSVDALQT 328

Query: 356 VFRNAASFKEVSDSLLTSSKGQLQKMKESLDDVMDYLVNNTPLNWLVGPFYPQLTE 411
            F +A  F++V  + L   +G++      +D++++ +V   PL WLVGPF P L E
Sbjct: 329 AFADARCFRDVPAAALAEGRGRVAHAHACVDELLELVVQAVPLPWLVGPFAPILVE 384


>gi|223718196 perilipin [Homo sapiens]
          Length = 522

 Score =  130 bits (327), Expect = 2e-30
 Identities = 117/453 (25%), Positives = 199/453 (43%), Gaps = 62/453 (13%)

Query: 9   QPSVVTRVVNLPLVSSTYDLMSSAYLSTKDQYPYLKSVCEMAENGVKTITSVAMTSALPI 68
           Q +V+ RV+ LP+VS T +     Y STK+ +P + SVC   E GV++ +S+A  S  P+
Sbjct: 17  QENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSASSLAAWSMEPV 76

Query: 69  IQKLEPQIAVANTYACKGLDRIEERLPILNQPSTQIVANAKGAVTGAKDAVTTTVTGAKD 128
           +++L  Q   AN  AC+GLD +EE++P L  P  +I +         KD ++T +  A++
Sbjct: 77  VRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASE-------LKDTISTRLRSARN 129

Query: 129 SVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSRMMQLVSSGVENALTKSELLVE 188
           S++  I    DK  GA     E    V   +      +R  +L S G + AL   E +VE
Sbjct: 130 SISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLALGSIEKVVE 189

Query: 189 QYLPLTEEELEKEAKKVEGFDLVQ-----KPSYYVRLGSLSTKLHSRAYQQALSRVKEAK 243
             LP  +E    E+    G    Q     KPS   R+G+L+  L SR   Q ++R   A 
Sbjct: 190 YLLPPDKE----ESAPAPGHQQAQKSPKAKPSLLSRVGALTNTL-SRYTVQTMAR---AL 241

Query: 244 QKSQQTISQLHSTVHLIEFARKNVYSANQKIQDAQDKLYLSWV-----------EWKRSI 292
           ++       +   V L   A+     A Q +   + ++ + W+           E +   
Sbjct: 242 EQGHTVAMWIPGVVPLSSLAQWGASVAMQAVSRRRSEVRVPWLHSLAAAQEEDHEDQTDT 301

Query: 293 GYDDTDESHCAEHIESRTLAIAR---------NLTQQLQTTCHTLLSNIQGVPQNIQDQA 343
             +DT+E    E  E++   +A           +   LQ T  T +S +   P  +    
Sbjct: 302 EGEDTEEEEELETEENKFSEVAALPGPRGLLGGVAHTLQKTLQTTISAVTWAPAAVLG-- 359

Query: 344 KHMGVMAGDIYSVFRNAASFKEVSDSLLTSSKGQLQKMKESL----DDVMDYLVNNTPLN 399
                MAG +  +    A         ++S+KG+   + ++L    D+V+D +V+  PL 
Sbjct: 360 -----MAGRVLHLTPAPA---------VSSTKGRAMSLSDALKGVTDNVVDTVVHYVPLP 405

Query: 400 WLVGPFYPQLTESQNAQDQGAEMDKSSQETQRS 432
            L        +E ++  +  AE+++   E + S
Sbjct: 406 RL--SLMEPESEFRDIDNPPAEVERREAERRAS 436


>gi|223718203 perilipin [Homo sapiens]
          Length = 522

 Score =  130 bits (327), Expect = 2e-30
 Identities = 117/453 (25%), Positives = 199/453 (43%), Gaps = 62/453 (13%)

Query: 9   QPSVVTRVVNLPLVSSTYDLMSSAYLSTKDQYPYLKSVCEMAENGVKTITSVAMTSALPI 68
           Q +V+ RV+ LP+VS T +     Y STK+ +P + SVC   E GV++ +S+A  S  P+
Sbjct: 17  QENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSASSLAAWSMEPV 76

Query: 69  IQKLEPQIAVANTYACKGLDRIEERLPILNQPSTQIVANAKGAVTGAKDAVTTTVTGAKD 128
           +++L  Q   AN  AC+GLD +EE++P L  P  +I +         KD ++T +  A++
Sbjct: 77  VRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASE-------LKDTISTRLRSARN 129

Query: 129 SVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSRMMQLVSSGVENALTKSELLVE 188
           S++  I    DK  GA     E    V   +      +R  +L S G + AL   E +VE
Sbjct: 130 SISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLALGSIEKVVE 189

Query: 189 QYLPLTEEELEKEAKKVEGFDLVQ-----KPSYYVRLGSLSTKLHSRAYQQALSRVKEAK 243
             LP  +E    E+    G    Q     KPS   R+G+L+  L SR   Q ++R   A 
Sbjct: 190 YLLPPDKE----ESAPAPGHQQAQKSPKAKPSLLSRVGALTNTL-SRYTVQTMAR---AL 241

Query: 244 QKSQQTISQLHSTVHLIEFARKNVYSANQKIQDAQDKLYLSWV-----------EWKRSI 292
           ++       +   V L   A+     A Q +   + ++ + W+           E +   
Sbjct: 242 EQGHTVAMWIPGVVPLSSLAQWGASVAMQAVSRRRSEVRVPWLHSLAAAQEEDHEDQTDT 301

Query: 293 GYDDTDESHCAEHIESRTLAIAR---------NLTQQLQTTCHTLLSNIQGVPQNIQDQA 343
             +DT+E    E  E++   +A           +   LQ T  T +S +   P  +    
Sbjct: 302 EGEDTEEEEELETEENKFSEVAALPGPRGLLGGVAHTLQKTLQTTISAVTWAPAAVLG-- 359

Query: 344 KHMGVMAGDIYSVFRNAASFKEVSDSLLTSSKGQLQKMKESL----DDVMDYLVNNTPLN 399
                MAG +  +    A         ++S+KG+   + ++L    D+V+D +V+  PL 
Sbjct: 360 -----MAGRVLHLTPAPA---------VSSTKGRAMSLSDALKGVTDNVVDTVVHYVPLP 405

Query: 400 WLVGPFYPQLTESQNAQDQGAEMDKSSQETQRS 432
            L        +E ++  +  AE+++   E + S
Sbjct: 406 RL--SLMEPESEFRDIDNPPAEVERREAERRAS 436


>gi|122937195 plasma membrane associated protein, S3-12 [Homo sapiens]
          Length = 1357

 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 71/273 (26%), Positives = 128/273 (46%), Gaps = 29/273 (10%)

Query: 141  TKGAVTGSVEKTKSVVSGSINTVLGSRMMQLVSSGVENA----LTKSEL--LVEQYLPLT 194
            TKG  T     T+    G  +T L +      + G E A    + ++EL  L + + P+ 
Sbjct: 1099 TKGLATDVATFTQGAAPGREDTGLLA-----TTHGPEEAPRLAMLQNELEGLGDIFHPMN 1153

Query: 195  EEELEKEAKKVEGFDLV--QKPSYYVRLGSLSTKLHSRAYQQALSRVKEAKQKSQQTISQ 252
             EE  + A    G  ++  ++ SY+VRLG L      RA++ A+S ++  + +++ T++Q
Sbjct: 1154 AEEQAQLAASQPGPKVLSAEQGSYFVRLGDLGPSFRQRAFEHAVSHLQHGQFQARDTLAQ 1213

Query: 253  LHSTVHLIEFARKNVYSANQKIQDAQDKLYLSWVEWKRSIGYDDTDESHCAEHIESRTLA 312
            L     LIE A        Q+  + Q +L        +  G    D +   E  ++  L+
Sbjct: 1214 LQDCFRLIEKA--------QQAPEGQPRL-------DQGSGASAEDAA-VQEERDAGVLS 1257

Query: 313  IARNLTQQLQTTCHTLLSNIQGVPQNIQDQAKHMGVMAGDIYSVFRNAASFKEVSDSLLT 372
                L +QL T    L+S++QG+P  +Q           ++Y +  +A S +E+    L 
Sbjct: 1258 RVCGLLRQLHTAYSGLVSSLQGLPAELQQPVGRARHSLCELYGIVASAGSVEELPAERLV 1317

Query: 373  SSKGQLQKMKESLDDVMDYLVNNTPLNWLVGPF 405
             S+  + +  + L+ +++ L +N PL+WLVGPF
Sbjct: 1318 QSREGVHQAWQGLEQLLEGLQHNPPLSWLVGPF 1350



 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 44/154 (28%), Positives = 78/154 (50%), Gaps = 13/154 (8%)

Query: 18  NLPLVSSTYDLMSSAYLSTKDQY---PYLKSVCEMAENGVKTITSVAMTSALPIIQK-LE 73
           +LP  SS  +L+++A+ S + +    P      E A+   +       T+  P  +K L+
Sbjct: 10  SLPGFSSARNLVANAHSSARARPAADPTGAPAAEAAQPQAQVAAHPEQTA--PWTEKELQ 67

Query: 74  PQ----IAVANTYACKGLDRIEERLPILNQPSTQIVANAKGAVTGAKDAVTTTVTGAKDS 129
           P     ++ A    C  + R ++ +   +     +V  AKG V G  D   + +TG K+ 
Sbjct: 68  PSEKQMVSGAKDLVCSKMSRAKDAV---SSGVASVVDVAKGVVQGGLDTTRSALTGTKEV 124

Query: 130 VASTITGVMDKTKGAVTGSVEKTKSVVSGSINTV 163
           V+S +TG MD  KGAV G ++ +K+V++G+ +TV
Sbjct: 125 VSSGVTGAMDMAKGAVQGGLDTSKAVLTGTKDTV 158



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 44/151 (29%), Positives = 69/151 (45%), Gaps = 9/151 (5%)

Query: 22  VSSTYDLMSSAYLSTKDQ-YPYLKSVCEMA----ENGVKTITSVAMTSALPIIQKLEPQI 76
           V +  D   +    TKD  Y  + S   +A    + G+KT  ++A  +       +   +
Sbjct: 602 VQTGMDTTKTVLTGTKDTIYSGVTSAVNVAKGAVQTGLKTTQNIATGTKNTFGSGVTSAV 661

Query: 77  AVANTYACKGLDRIEERLPILNQPSTQ----IVANAKGAVTGAKDAVTTTVTGAKDSVAS 132
            VA   A  G+D  +  L       T      V  AKG V  + D   T +TG KD+V S
Sbjct: 662 NVAKGAAQTGVDTAKTVLTGTKDTVTTGLMGAVNVAKGTVQTSVDTTKTVLTGTKDTVCS 721

Query: 133 TITGVMDKTKGAVTGSVEKTKSVVSGSINTV 163
            +TG  +  KGA+ G ++ TKSV++G+ + V
Sbjct: 722 GVTGAANVAKGAIQGGLDTTKSVLTGTKDAV 752



 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)

Query: 52  NGVKTITSVAMTSALPIIQK-LEPQIAVANTYACKGLDRIEERLP----ILNQPSTQIVA 106
           +G K +    M+ A   +   +   + VA      GLD     L     +++   T  + 
Sbjct: 75  SGAKDLVCSKMSRAKDAVSSGVASVVDVAKGVVQGGLDTTRSALTGTKEVVSSGVTGAMD 134

Query: 107 NAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTV 163
            AKGAV G  D     +TG KD+V++ +TG ++  KG V   V+ TK+V++G+ +TV
Sbjct: 135 MAKGAVQGGLDTSKAVLTGTKDTVSTGLTGAVNVAKGTVQAGVDTTKTVLTGTKDTV 191



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 27/82 (32%), Positives = 45/82 (54%), Gaps = 2/82 (2%)

Query: 108 AKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLG-- 165
           AKG +    D   T +TG KD+V S +TG M+  KG +   V+ TK+V++G+ NTV    
Sbjct: 301 AKGTIQTGVDTSKTVLTGTKDTVCSGVTGAMNVAKGTIQTGVDTTKTVLTGTKNTVCSGV 360

Query: 166 SRMMQLVSSGVENALTKSELLV 187
           +  + L    ++  L  ++ +V
Sbjct: 361 TGAVNLAKEAIQGGLDTTKSMV 382



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 31/88 (35%), Positives = 51/88 (57%), Gaps = 9/88 (10%)

Query: 108 AKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSR 167
           AKGAV G  D   + +TG KD+V++ +TG ++  KG V   V+ TK+V++G+ +T     
Sbjct: 466 AKGAVQGGLDTTKSVLTGTKDAVSTGLTGAVNVAKGTVQTGVDTTKTVLTGTKDT----- 520

Query: 168 MMQLVSSGVENALTKSELLVEQYLPLTE 195
               V SGV +A+  ++  V+  L  T+
Sbjct: 521 ----VCSGVTSAVNVAKGAVQGGLDTTK 544



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 33/86 (38%), Positives = 44/86 (51%), Gaps = 22/86 (25%)

Query: 105  VANAKGAVTGAKDAVTTTVTGA----------------------KDSVASTITGVMDKTK 142
            V  AK  ++GAKDAVTT VTGA                      KD+V S +TG M   K
Sbjct: 936  VDTAKTVLSGAKDAVTTGVTGAVNVAKGTVQTGVDASKAVLMGTKDTVFSGVTGAMSMAK 995

Query: 143  GAVTGSVEKTKSVVSGSINTVLGSRM 168
            GAV G ++ TK+V++G+ + V    M
Sbjct: 996  GAVQGGLDTTKTVLTGTKDAVSAGLM 1021



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 27/62 (43%), Positives = 37/62 (59%)

Query: 102 TQIVANAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSIN 161
           T  V  AKG V    D   T +TG KD+V S +T  ++  KGAV G ++ TKSVV G+ +
Sbjct: 493 TGAVNVAKGTVQTGVDTTKTVLTGTKDTVCSGVTSAVNVAKGAVQGGLDTTKSVVIGTKD 552

Query: 162 TV 163
           T+
Sbjct: 553 TM 554



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 23/56 (41%), Positives = 38/56 (67%)

Query: 108 AKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTV 163
           AKGAV G  D   + +TG KD+V++ +TG ++  KG V   V+ +K+V++G+ +TV
Sbjct: 862 AKGAVQGGLDTTKSVLTGTKDAVSTGLTGAVNLAKGTVQTGVDTSKTVLTGTKDTV 917



 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 33/94 (35%), Positives = 47/94 (50%), Gaps = 9/94 (9%)

Query: 102 TQIVANAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSIN 161
           T  V  AKG V    D   T +TG KD+V S +TG  +  KGAV   V+  K+V++G+ +
Sbjct: 757 TGAVKLAKGTVQTGMDTTKTVLTGTKDAVCSGVTGAANVAKGAVQMGVDTAKTVLTGTKD 816

Query: 162 TVLGSRMMQLVSSGVENALTKSELLVEQYLPLTE 195
           T         V SGV  A   ++  V+  L  T+
Sbjct: 817 T---------VCSGVTGAANVAKGAVQTGLKTTQ 841



 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 25/62 (40%), Positives = 38/62 (61%)

Query: 102 TQIVANAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSIN 161
           T  V  AKGAV G  D   + V G KD++++ +TG  +  KGAV   V+  K+V++G+ +
Sbjct: 526 TSAVNVAKGAVQGGLDTTKSVVIGTKDTMSTGLTGAANVAKGAVQTGVDTAKTVLTGTKD 585

Query: 162 TV 163
           TV
Sbjct: 586 TV 587



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 26/59 (44%), Positives = 37/59 (62%), Gaps = 1/59 (1%)

Query: 108 AKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGS 166
           AKGAV    D   T +TG KD+V S +TG  +  KGAV   ++ T+++ +G+ NT LGS
Sbjct: 796 AKGAVQMGVDTAKTVLTGTKDTVCSGVTGAANVAKGAVQTGLKTTQNIATGTKNT-LGS 853



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 32/97 (32%), Positives = 51/97 (52%), Gaps = 9/97 (9%)

Query: 102  TQIVANAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSIN 161
            T  V  AKG V    D   T ++GAKD+V + +TG ++  KG V   V+ +K+V+ G+ +
Sbjct: 922  TGAVNVAKGTVQTGVDTAKTVLSGAKDAVTTGVTGAVNVAKGTVQTGVDASKAVLMGTKD 981

Query: 162  TVLGSRMMQLVSSGVENALTKSELLVEQYLPLTEEEL 198
            TV          SGV  A++ ++  V+  L  T+  L
Sbjct: 982  TVF---------SGVTGAMSMAKGAVQGGLDTTKTVL 1009



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 22/56 (39%), Positives = 35/56 (62%)

Query: 108 AKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTV 163
           AKG +    D   T +TG KD+V S +TG M+  KG +   V+ +K+V++G+ +TV
Sbjct: 268 AKGTIQTGVDTSKTVLTGTKDTVCSGVTGAMNVAKGTIQTGVDTSKTVLTGTKDTV 323



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 4/117 (3%)

Query: 51  ENGVKTITSVAMTSALPIIQKLEPQIAVANTYACKGLDRIEERLP----ILNQPSTQIVA 106
           + G+KT  ++A  +   +   +     VA      GLD  +  L      ++   T  V 
Sbjct: 834 QTGLKTTQNIATGTKNTLGSGVTGAAKVAKGAVQGGLDTTKSVLTGTKDAVSTGLTGAVN 893

Query: 107 NAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTV 163
            AKG V    D   T +TG KD+V S +TG ++  KG V   V+  K+V+SG+ + V
Sbjct: 894 LAKGTVQTGVDTSKTVLTGTKDTVCSGVTGAVNVAKGTVQTGVDTAKTVLSGAKDAV 950



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 23/62 (37%), Positives = 38/62 (61%)

Query: 102 TQIVANAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSIN 161
           T  V  A+G++    D   T +TG KD+V S +TG M+  KG +   V+ +K+V++G+ +
Sbjct: 229 TGAVNVARGSIQTGVDTSKTVLTGTKDTVCSGVTGAMNVAKGTIQTGVDTSKTVLTGTKD 288

Query: 162 TV 163
           TV
Sbjct: 289 TV 290



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 22/56 (39%), Positives = 34/56 (60%)

Query: 108 AKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTV 163
           A+G +    D     +TG KD+V S +TG  +  KGAV G ++ TKSV++G+ + V
Sbjct: 433 ARGTIQTGVDTTKIVLTGTKDTVCSGVTGAANVAKGAVQGGLDTTKSVLTGTKDAV 488



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 28/88 (31%), Positives = 48/88 (54%), Gaps = 9/88 (10%)

Query: 108 AKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSR 167
           AKGAV    D   T +TG KD+V + + G ++  KG V   ++ TK+V++G+ +T+    
Sbjct: 565 AKGAVQTGVDTAKTVLTGTKDTVTTGLVGAVNVAKGTVQTGMDTTKTVLTGTKDTIY--- 621

Query: 168 MMQLVSSGVENALTKSELLVEQYLPLTE 195
                 SGV +A+  ++  V+  L  T+
Sbjct: 622 ------SGVTSAVNVAKGAVQTGLKTTQ 643



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 21/56 (37%), Positives = 36/56 (64%)

Query: 108 AKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTV 163
           AKGA+ G  D   + +TG KD+V++ +TG +   KG V   ++ TK+V++G+ + V
Sbjct: 730 AKGAIQGGLDTTKSVLTGTKDAVSTGLTGAVKLAKGTVQTGMDTTKTVLTGTKDAV 785



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 21/56 (37%), Positives = 35/56 (62%)

Query: 108 AKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTV 163
           AKG +    D   T +TG K++V S +TG ++  K A+ G ++ TKS+V G+ +T+
Sbjct: 334 AKGTIQTGVDTTKTVLTGTKNTVCSGVTGAVNLAKEAIQGGLDTTKSMVMGTKDTM 389



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 28/73 (38%), Positives = 39/73 (53%), Gaps = 5/73 (6%)

Query: 109 KGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSRM 168
           K  +TG KDAV+T +TGA      T+   MD TK  +TG+ +   S V+G+ N   G+  
Sbjct: 742 KSVLTGTKDAVSTGLTGAVKLAKGTVQTGMDTTKTVLTGTKDAVCSGVTGAANVAKGA-- 799

Query: 169 MQLVSSGVENALT 181
              V  GV+ A T
Sbjct: 800 ---VQMGVDTAKT 809



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 26/73 (35%), Positives = 42/73 (57%), Gaps = 5/73 (6%)

Query: 109 KGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSRM 168
           K  +TG KDAV+T +TGA +    T+   +D +K  +TG+ +   S V+G++N   G+  
Sbjct: 874 KSVLTGTKDAVSTGLTGAVNLAKGTVQTGVDTSKTVLTGTKDTVCSGVTGAVNVAKGT-- 931

Query: 169 MQLVSSGVENALT 181
              V +GV+ A T
Sbjct: 932 ---VQTGVDTAKT 941



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 42/152 (27%), Positives = 70/152 (46%), Gaps = 9/152 (5%)

Query: 21  LVSSTYDLMSSAYLSTKDQYPY-LKSVCEMAENGVK---TITSVAMTSALPIIQK-LEPQ 75
           +VS   DL+ S     KD     + SV ++A+  V+     T  A+T    ++   +   
Sbjct: 73  MVSGAKDLVCSKMSRAKDAVSSGVASVVDVAKGVVQGGLDTTRSALTGTKEVVSSGVTGA 132

Query: 76  IAVANTYACKGLDRIEERLP----ILNQPSTQIVANAKGAVTGAKDAVTTTVTGAKDSVA 131
           + +A      GLD  +  L      ++   T  V  AKG V    D   T +TG KD+V 
Sbjct: 133 MDMAKGAVQGGLDTSKAVLTGTKDTVSTGLTGAVNVAKGTVQAGVDTTKTVLTGTKDTVT 192

Query: 132 STITGVMDKTKGAVTGSVEKTKSVVSGSINTV 163
           + + G ++  KG V   VE +K+V++G+ + V
Sbjct: 193 TGVMGAVNLAKGTVQTGVETSKAVLTGTKDAV 224



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 22/73 (30%), Positives = 41/73 (56%), Gaps = 5/73 (6%)

Query: 109 KGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSRM 168
           + A+TG K+ V++ VTGA D     + G +D +K  +TG+ +   + ++G++N   G+  
Sbjct: 115 RSALTGTKEVVSSGVTGAMDMAKGAVQGGLDTSKAVLTGTKDTVSTGLTGAVNVAKGT-- 172

Query: 169 MQLVSSGVENALT 181
              V +GV+   T
Sbjct: 173 ---VQAGVDTTKT 182



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 26/79 (32%), Positives = 42/79 (53%), Gaps = 5/79 (6%)

Query: 105 VANAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVL 164
           V  AK  +TG KD VTT + GA +    T+   MD TK  +TG+ +   S V+ ++N   
Sbjct: 573 VDTAKTVLTGTKDTVTTGLVGAVNVAKGTVQTGMDTTKTVLTGTKDTIYSGVTSAVNVAK 632

Query: 165 GS-----RMMQLVSSGVEN 178
           G+     +  Q +++G +N
Sbjct: 633 GAVQTGLKTTQNIATGTKN 651



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 8/81 (9%)

Query: 108 AKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSR 167
           AKG V    D   T +TG KD++ S +T  ++  KGAV   ++ T+++ +G+ NT  GS 
Sbjct: 598 AKGTVQTGMDTTKTVLTGTKDTIYSGVTSAVNVAKGAVQTGLKTTQNIATGTKNT-FGSG 656

Query: 168 MMQLVS-------SGVENALT 181
           +   V+       +GV+ A T
Sbjct: 657 VTSAVNVAKGAAQTGVDTAKT 677



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 24/72 (33%), Positives = 40/72 (55%), Gaps = 5/72 (6%)

Query: 108 AKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSR 167
           +K  +TG KD V+T +TGA +    T+   +D TK  +TG+ +   + V G++N   G+ 
Sbjct: 147 SKAVLTGTKDTVSTGLTGAVNVAKGTVQAGVDTTKTVLTGTKDTVTTGVMGAVNLAKGT- 205

Query: 168 MMQLVSSGVENA 179
               V +GVE +
Sbjct: 206 ----VQTGVETS 213



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 29/91 (31%), Positives = 45/91 (49%), Gaps = 9/91 (9%)

Query: 108 AKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSR 167
           AKGA+    +      TG KD+V S +TG M+  +G +   V+ TK V++G+ +T     
Sbjct: 400 AKGAMQTGLNTTQNIATGTKDTVCSGVTGAMNLARGTIQTGVDTTKIVLTGTKDT----- 454

Query: 168 MMQLVSSGVENALTKSELLVEQYLPLTEEEL 198
               V SGV  A   ++  V+  L  T+  L
Sbjct: 455 ----VCSGVTGAANVAKGAVQGGLDTTKSVL 481



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 5/77 (6%)

Query: 105 VANAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVL 164
           V   K  +TG KD V + VTGA +     + G +D TK  +TG+ +   + ++G++N   
Sbjct: 441 VDTTKIVLTGTKDTVCSGVTGAANVAKGAVQGGLDTTKSVLTGTKDAVSTGLTGAVNVAK 500

Query: 165 GSRMMQLVSSGVENALT 181
           G+     V +GV+   T
Sbjct: 501 GT-----VQTGVDTTKT 512



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 46/175 (26%), Positives = 78/175 (44%), Gaps = 17/175 (9%)

Query: 3   SVAVDPQPSVVTRVVNLP--LVSSTYDLMSSAYLSTKDQYPY-LKSVCEMA----ENGVK 55
           S A D   S V  VV++   +V    D   SA   TK+     +    +MA    + G+ 
Sbjct: 86  SRAKDAVSSGVASVVDVAKGVVQGGLDTTRSALTGTKEVVSSGVTGAMDMAKGAVQGGLD 145

Query: 56  TITSVAMTSALPIIQKLEPQIAVANTYACKGLDRIEERLPILNQPSTQIVANAKGAVTGA 115
           T  +V   +   +   L   + VA      G+D  +    +L      +     GAV  A
Sbjct: 146 TSKAVLTGTKDTVSTGLTGAVNVAKGTVQAGVDTTKT---VLTGTKDTVTTGVMGAVNLA 202

Query: 116 KDAVTTTV-------TGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTV 163
           K  V T V       TG KD+V++ +TG ++  +G++   V+ +K+V++G+ +TV
Sbjct: 203 KGTVQTGVETSKAVLTGTKDAVSTGLTGAVNVARGSIQTGVDTSKTVLTGTKDTV 257



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 22/56 (39%), Positives = 32/56 (57%)

Query: 108 AKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTV 163
           AKGAV           TG K+++ S +TG     KGAV G ++ TKSV++G+ + V
Sbjct: 829 AKGAVQTGLKTTQNIATGTKNTLGSGVTGAAKVAKGAVQGGLDTTKSVLTGTKDAV 884



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 5/77 (6%)

Query: 105 VANAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVL 164
           V   K  +TG KD VTT V GA +    T+   ++ +K  +TG+ +   + ++G++N   
Sbjct: 177 VDTTKTVLTGTKDTVTTGVMGAVNLAKGTVQTGVETSKAVLTGTKDAVSTGLTGAVNVAR 236

Query: 165 GSRMMQLVSSGVENALT 181
           GS     + +GV+ + T
Sbjct: 237 GS-----IQTGVDTSKT 248



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 25/77 (32%), Positives = 42/77 (54%), Gaps = 5/77 (6%)

Query: 105 VANAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVL 164
           V  +K  +TG KD V + VTGA +    TI   +D +K  +TG+ +   S V+G++N   
Sbjct: 243 VDTSKTVLTGTKDTVCSGVTGAMNVAKGTIQTGVDTSKTVLTGTKDTVCSGVTGAMNVAK 302

Query: 165 GSRMMQLVSSGVENALT 181
           G+     + +GV+ + T
Sbjct: 303 GT-----IQTGVDTSKT 314



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 5/77 (6%)

Query: 105 VANAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVL 164
           V   K  +TG KD V + VTGA +     I G +D TK  +TG+ +   + ++G++    
Sbjct: 705 VDTTKTVLTGTKDTVCSGVTGAANVAKGAIQGGLDTTKSVLTGTKDAVSTGLTGAVKLAK 764

Query: 165 GSRMMQLVSSGVENALT 181
           G+     V +G++   T
Sbjct: 765 GT-----VQTGMDTTKT 776



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 20/62 (32%), Positives = 36/62 (58%)

Query: 102 TQIVANAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSIN 161
           T  V  AK A+ G  D   + V G KD++++ +TG  +  KGA+   +  T+++ +G+ +
Sbjct: 361 TGAVNLAKEAIQGGLDTTKSMVMGTKDTMSTGLTGAANVAKGAMQTGLNTTQNIATGTKD 420

Query: 162 TV 163
           TV
Sbjct: 421 TV 422



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 5/77 (6%)

Query: 105 VANAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVL 164
           V   K  +TG KD V + VT A +     + G +D TK  V G+ +   + ++G+ N   
Sbjct: 507 VDTTKTVLTGTKDTVCSGVTSAVNVAKGAVQGGLDTTKSVVIGTKDTMSTGLTGAANVAK 566

Query: 165 GSRMMQLVSSGVENALT 181
           G+     V +GV+ A T
Sbjct: 567 GA-----VQTGVDTAKT 578



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 26/73 (35%), Positives = 40/73 (54%), Gaps = 5/73 (6%)

Query: 99  QPST-QIVANAKGAVTG----AKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTK 153
           QPS  Q+V+ AK  V      AKDAV++ V    D     + G +D T+ A+TG+ E   
Sbjct: 67  QPSEKQMVSGAKDLVCSKMSRAKDAVSSGVASVVDVAKGVVQGGLDTTRSALTGTKEVVS 126

Query: 154 SVVSGSINTVLGS 166
           S V+G+++   G+
Sbjct: 127 SGVTGAMDMAKGA 139



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 2/77 (2%)

Query: 105 VANAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVL 164
           V   K  +TG K+ V + VTGA +     I G +D TK  V G+ +   + ++G+ N   
Sbjct: 342 VDTTKTVLTGTKNTVCSGVTGAVNLAKEAIQGGLDTTKSMVMGTKDTMSTGLTGAANVAK 401

Query: 165 GSRMMQLVSSGVENALT 181
           G+  MQ   +  +N  T
Sbjct: 402 GA--MQTGLNTTQNIAT 416



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 19/59 (32%), Positives = 30/59 (50%)

Query: 108  AKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGS 166
            +K  + G KD V + VTGA       + G +D TK  +TG+ +   + + GS N   G+
Sbjct: 972  SKAVLMGTKDTVFSGVTGAMSMAKGAVQGGLDTTKTVLTGTKDAVSAGLMGSGNVATGA 1030



 Score = 33.9 bits (76), Expect = 0.30
 Identities = 17/43 (39%), Positives = 25/43 (58%)

Query: 102  TQIVANAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGA 144
            T  ++ AKGAV G  D   T +TG KD+V++ + G  +   GA
Sbjct: 988  TGAMSMAKGAVQGGLDTTKTVLTGTKDAVSAGLMGSGNVATGA 1030



 Score = 32.3 bits (72), Expect = 0.87
 Identities = 42/178 (23%), Positives = 65/178 (36%), Gaps = 22/178 (12%)

Query: 11  SVVTRVVNLP--LVSSTYDLMSSAYLSTKDQYPY-LKSVCEMAENGVKTITSVAMTSAL- 66
           S VT  VN+    V    D   S  + TKD     L     +A+  V+T    A T    
Sbjct: 523 SGVTSAVNVAKGAVQGGLDTTKSVVIGTKDTMSTGLTGAANVAKGAVQTGVDTAKTVLTG 582

Query: 67  ---PIIQKLEPQIAVANTYACKGLDRIEERLP----ILNQPSTQIVANAKGAVTGAKDAV 119
               +   L   + VA      G+D  +  L      +    T  V  AKGAV       
Sbjct: 583 TKDTVTTGLVGAVNVAKGTVQTGMDTTKTVLTGTKDTIYSGVTSAVNVAKGAVQTGLKTT 642

Query: 120 TTTVTGAKDSVASTITGVMDKTKG-----------AVTGSVEKTKSVVSGSINTVLGS 166
               TG K++  S +T  ++  KG            +TG+ +   + + G++N   G+
Sbjct: 643 QNIATGTKNTFGSGVTSAVNVAKGAAQTGVDTAKTVLTGTKDTVTTGLMGAVNVAKGT 700


>gi|10440566 leucine zipper, putative tumor suppressor 1 [Homo
           sapiens]
          Length = 596

 Score = 37.0 bits (84), Expect = 0.035
 Identities = 54/259 (20%), Positives = 105/259 (40%), Gaps = 17/259 (6%)

Query: 187 VEQYLPLTEEELEKEAKKVEGFDLVQKPSYYVRLGSLSTKLHSRAYQQALSRVKEAKQKS 246
           +EQ L   E  L+K  +  E  +L    +Y  R      +L     +   +++K+A QKS
Sbjct: 266 LEQKLLEREGALQKLQRSFEEKELASSLAYEERPRRCRDELEGPEPKGG-NKLKQASQKS 324

Query: 247 QQTISQLHSTVHLIEFARKNVYSANQKIQDAQDKL---YLSWVEWKRSIG--YDDTDESH 301
           Q+    LH  V  ++  ++ +    + +   QD L     S+   K S G   ++T    
Sbjct: 325 QRAQQVLHLQVLQLQQEKRQLRQELESLMKEQDLLETKLRSYEREKTSFGPALEETQWEV 384

Query: 302 CAEHIESRTLAIARNLTQQLQTTCHTLLSNIQGVPQNIQD---QAKHMGVMAGDIYSVFR 358
           C    +S  +++ +   ++ QT  +   S I G+   ++D   + + + +   D+    R
Sbjct: 385 CQ---KSGEISLLKQQLKESQTEVNAKASEILGLKAQLKDTRGKLEGLELRTQDLEGALR 441

Query: 359 NAASFKEVSDSLLTSSKGQLQKMKES---LDDVMDYLVNNTPLNWLVGPFYPQLTESQNA 415
                 EV ++ L   K + + ++E    L+  +  L     L   +GP  P   E   A
Sbjct: 442 TKGLELEVCENELQRKKNEAELLREKVNLLEQELQELRAQAALARDMGP--PTFPEDVPA 499

Query: 416 QDQGAEMDKSSQETQRSEH 434
             +  E  ++    +R  H
Sbjct: 500 LQRELERLRAELREERQGH 518


>gi|122937396 coiled-coil domain containing 150 [Homo sapiens]
          Length = 1101

 Score = 36.6 bits (83), Expect = 0.046
 Identities = 27/125 (21%), Positives = 52/125 (41%), Gaps = 17/125 (13%)

Query: 233 QQALSRVKEAKQKSQQTISQLHSTVHLIEFARKNVYSANQKIQDAQDKLYLSWVEWKRSI 292
           +Q L  VKE + K+Q  + +L +T+ +    +KN     ++++  + K+ L   E +R +
Sbjct: 161 RQQLRAVKEEEDKAQDEVQRLTATLKIASQTKKNAAIIEEELKTTKRKMNLKIQELRRQL 220

Query: 293 GYDDTDESHCAEHIE-------------SRTLAIARNLTQQLQTTCHTLLSNIQGVPQNI 339
                 E +  E +E               T+ + R     LQ  C  L  +IQ   + +
Sbjct: 221 ----AQEKYLRESLEKSASAMLLKIQEMGSTVEVERKQVHILQQNCIALRDSIQSAQELL 276

Query: 340 QDQAK 344
             + K
Sbjct: 277 AQEQK 281


>gi|114155142 nuclear pore complex-associated protein TPR [Homo
            sapiens]
          Length = 2363

 Score = 35.4 bits (80), Expect = 0.10
 Identities = 59/290 (20%), Positives = 113/290 (38%), Gaps = 45/290 (15%)

Query: 133  TITGVMDK----TKGAVTGSVEKTKSVVSG---SINTVLGSRMMQLVSSGVENALTKSEL 185
            TI G++++    TK  ++  +EK +  +S     +   +  R     +  V+   TK +L
Sbjct: 821  TIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQL 880

Query: 186  LVEQYLPLTEEELEKEAKKVEGFDLVQKPSYYVRLGSLSTKLHS---------------- 229
              E  L L  +EL K A+K          +  V++ S S++                   
Sbjct: 881  DTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQ 940

Query: 230  -RAYQQALSRVKEAKQKSQQTISQLHSTV-----------HLIEFARKNVYSANQKIQDA 277
             R  ++ ++ +KE  + S   + Q  + V            + E  RKN+    ++  + 
Sbjct: 941  LRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEF 1000

Query: 278  QDKLYLSWVEWKRSIGYDDTDESHCAEHIES------RTLAIARNLTQQLQTTCHTLLSN 331
            Q +L    +E ++       D+    E +E       +TL+  +N  Q+      T LSN
Sbjct: 1001 QTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSN 1060

Query: 332  IQGVPQNIQDQAKHMGVMAGDIYSVFRNAASFKEVSDSLLTSSKGQLQKM 381
             Q   ++ Q+QAK    +A +  + +             L ++K Q+ KM
Sbjct: 1061 EQQARRDCQEQAK----IAVEAQNKYERELMLHAADVEALQAAKEQVSKM 1106


>gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]
          Length = 1111

 Score = 34.7 bits (78), Expect = 0.18
 Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 16/162 (9%)

Query: 234  QALSRVKEAKQKSQQTISQLHSTVHLIEFARKNVYS-----ANQKIQDAQDKLYLSWVEW 288
            Q LSR   AK ++Q+ +S  ++T + +E   KN+        N+K +  +    LS++  
Sbjct: 922  QLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQ 981

Query: 289  KRSIGYDDTDESHCAEHIESRTLAIARNLTQQLQTTCHTLLSNIQGVPQNIQDQAKHMGV 348
            K S   D T ++        R L  A    Q+ +      L     + Q I        V
Sbjct: 982  KVSDASDKTQQA-------ERALGSAAADAQRAKNGAGEALEISSEIEQEIGSLNLEANV 1034

Query: 349  MAGDIYSVFRNAASFKEVSDSLLTSSKGQLQKMKESLDDVMD 390
             A    ++ +  AS K    S +   +G+L++ +   D  MD
Sbjct: 1035 TADGALAMEKGLASLK----SEMREVEGELERKELEFDTNMD 1072


>gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]
          Length = 1193

 Score = 34.7 bits (78), Expect = 0.18
 Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 16/162 (9%)

Query: 234  QALSRVKEAKQKSQQTISQLHSTVHLIEFARKNVYS-----ANQKIQDAQDKLYLSWVEW 288
            Q LSR   AK ++Q+ +S  ++T + +E   KN+        N+K +  +    LS++  
Sbjct: 922  QLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQ 981

Query: 289  KRSIGYDDTDESHCAEHIESRTLAIARNLTQQLQTTCHTLLSNIQGVPQNIQDQAKHMGV 348
            K S   D T ++        R L  A    Q+ +      L     + Q I        V
Sbjct: 982  KVSDASDKTQQA-------ERALGSAAADAQRAKNGAGEALEISSEIEQEIGSLNLEANV 1034

Query: 349  MAGDIYSVFRNAASFKEVSDSLLTSSKGQLQKMKESLDDVMD 390
             A    ++ +  AS K    S +   +G+L++ +   D  MD
Sbjct: 1035 TADGALAMEKGLASLK----SEMREVEGELERKELEFDTNMD 1072


>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
          Length = 1417

 Score = 34.3 bits (77), Expect = 0.23
 Identities = 37/193 (19%), Positives = 78/193 (40%), Gaps = 22/193 (11%)

Query: 202 AKKVEGFDLVQKPSYYVRLGSLSTKLHSRAYQQALSRVKEAKQKSQQTISQLHSTVHLIE 261
           A +   F L+Q+    +   S S+KL S   ++    +   KQ  ++ ++         E
Sbjct: 665 AHRTSQFQLIQEE--LLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAE 722

Query: 262 FARKNVYSANQKIQDAQDKLYLSWVEWKRSIGYDDTDESHCAEHIESRTLAIARNLTQQL 321
             ++ +   N+KI+  +  +       K  + ++   + H  +H             +++
Sbjct: 723 LEQE-LMEKNEKIRSLETNINTE--HEKICLAFEKAKKIHLEQH-------------KEM 766

Query: 322 QTTCHTLLSNIQGVPQNIQDQAKHMGVMAGDIYSVFRNAASFKEVSDSLLTSSKGQLQKM 381
           +     L + ++   Q  ++Q K M ++  DI     +  S     D LLT SKG+++K 
Sbjct: 767 EKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESL----DRLLTESKGEMKKE 822

Query: 382 KESLDDVMDYLVN 394
               D+ +  L N
Sbjct: 823 NMKKDEALKALQN 835


>gi|4826934 protein phosphatase 4, regulatory subunit 1 isoform b
           [Homo sapiens]
          Length = 933

 Score = 34.3 bits (77), Expect = 0.23
 Identities = 41/189 (21%), Positives = 77/189 (40%), Gaps = 24/189 (12%)

Query: 233 QQALSRVKEAKQKSQQTISQLHSTVHLIEFARKNVYSANQ----KIQDAQDKL----YLS 284
           + ++  + +A +    T+  +HS   L   +  + +S ++    K+QD   +     YLS
Sbjct: 554 EDSVPLISDAVENMDSTLHYIHSDSDL---SNNSSFSPDEERRTKVQDVVPQALLDQYLS 610

Query: 285 WVEWKRSIGYDDTDESHCAEHIESRTLAIARNLTQQLQTTCHTLLSNIQ-----GVPQNI 339
             +  R+   D     HCA  +    L + R     L+ T  TL S++Q      +  +I
Sbjct: 611 MTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSI 670

Query: 340 QDQAKHMG--VMAGDIYSVFRN-AASFKEVSDSLLTSSKG-----QLQKMKESLDDVMDY 391
            + A  +G  + A D+  +F        EV   +L           + K +E L  + ++
Sbjct: 671 HELAVILGDQLTAADLVPIFNGFLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEF 730

Query: 392 LVNNTPLNW 400
           LV +   NW
Sbjct: 731 LVTDNSRNW 739


>gi|108936953 protein phosphatase 4, regulatory subunit 1 isoform a
           [Homo sapiens]
          Length = 950

 Score = 34.3 bits (77), Expect = 0.23
 Identities = 41/189 (21%), Positives = 77/189 (40%), Gaps = 24/189 (12%)

Query: 233 QQALSRVKEAKQKSQQTISQLHSTVHLIEFARKNVYSANQ----KIQDAQDKL----YLS 284
           + ++  + +A +    T+  +HS   L   +  + +S ++    K+QD   +     YLS
Sbjct: 571 EDSVPLISDAVENMDSTLHYIHSDSDL---SNNSSFSPDEERRTKVQDVVPQALLDQYLS 627

Query: 285 WVEWKRSIGYDDTDESHCAEHIESRTLAIARNLTQQLQTTCHTLLSNIQ-----GVPQNI 339
             +  R+   D     HCA  +    L + R     L+ T  TL S++Q      +  +I
Sbjct: 628 MTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSI 687

Query: 340 QDQAKHMG--VMAGDIYSVFRN-AASFKEVSDSLLTSSKG-----QLQKMKESLDDVMDY 391
            + A  +G  + A D+  +F        EV   +L           + K +E L  + ++
Sbjct: 688 HELAVILGDQLTAADLVPIFNGFLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEF 747

Query: 392 LVNNTPLNW 400
           LV +   NW
Sbjct: 748 LVTDNSRNW 756


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 33.9 bits (76), Expect = 0.30
 Identities = 50/240 (20%), Positives = 83/240 (34%), Gaps = 6/240 (2%)

Query: 90   IEERLPILNQPSTQIVANAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSV 149
            + E +  L Q   Q+    +             V      V+S + GV+  T     GSV
Sbjct: 976  LNEEVKSLKQEKEQVSLRCRELEIIINHNRAENVQSCDTQVSSLLDGVVTMTSRGAEGSV 1035

Query: 150  EKT-KSVVSGSINTVLGSRMMQLVSSGVENALTKSELLVEQYLPLTEEELEKEAKKVEGF 208
             K  KS    S   V      + ++ G E+   K E L+  +LP   +E    A +    
Sbjct: 1036 SKVNKSFGEESKIMVEDKVSFENMTVGEES---KQEQLILDHLPSVTKESSLRATQPSEN 1092

Query: 209  DLVQKPSYYVRLGSLSTKLHSRAYQQALSRVKEAKQKSQQTISQLHSTVHLIEFARKNVY 268
            D +QK    ++      +L   A +  LS V        +   +      L     + ++
Sbjct: 1093 DKLQKELNVLKSEQNDLRLQMEAQRICLSLVYSTHVDQVREYMENEKDKALCSLKEELIF 1152

Query: 269  SANQKIQDAQDKLYLSWVEWKRSIGYDDTDESHCAEHIESRTLAIARNLTQQLQTTCHTL 328
            +  +KI++ Q    L     K     D+    H    I     A++   +  LQT C  L
Sbjct: 1153 AQEEKIKELQKIHQLELQTMKTQETGDEGKPLHLL--IGKLQKAVSEECSYFLQTLCSVL 1210


>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
          Length = 3899

 Score = 33.9 bits (76), Expect = 0.30
 Identities = 50/240 (20%), Positives = 83/240 (34%), Gaps = 6/240 (2%)

Query: 90   IEERLPILNQPSTQIVANAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSV 149
            + E +  L Q   Q+    +             V      V+S + GV+  T     GSV
Sbjct: 976  LNEEVKSLKQEKEQVSLRCRELEIIINHNRAENVQSCDTQVSSLLDGVVTMTSRGAEGSV 1035

Query: 150  EKT-KSVVSGSINTVLGSRMMQLVSSGVENALTKSELLVEQYLPLTEEELEKEAKKVEGF 208
             K  KS    S   V      + ++ G E+   K E L+  +LP   +E    A +    
Sbjct: 1036 SKVNKSFGEESKIMVEDKVSFENMTVGEES---KQEQLILDHLPSVTKESSLRATQPSEN 1092

Query: 209  DLVQKPSYYVRLGSLSTKLHSRAYQQALSRVKEAKQKSQQTISQLHSTVHLIEFARKNVY 268
            D +QK    ++      +L   A +  LS V        +   +      L     + ++
Sbjct: 1093 DKLQKELNVLKSEQNDLRLQMEAQRICLSLVYSTHVDQVREYMENEKDKALCSLKEELIF 1152

Query: 269  SANQKIQDAQDKLYLSWVEWKRSIGYDDTDESHCAEHIESRTLAIARNLTQQLQTTCHTL 328
            +  +KI++ Q    L     K     D+    H    I     A++   +  LQT C  L
Sbjct: 1153 AQEEKIKELQKIHQLELQTMKTQETGDEGKPLHLL--IGKLQKAVSEECSYFLQTLCSVL 1210


>gi|53729363 leucine rich repeat and sterile alpha motif containing
           1 [Homo sapiens]
          Length = 723

 Score = 33.5 bits (75), Expect = 0.39
 Identities = 36/172 (20%), Positives = 72/172 (41%), Gaps = 20/172 (11%)

Query: 91  EERLPILNQPSTQIVANAKGAVTGAKDAVTTTVTGAKDSVASTITGV---MDKTKGAVTG 147
           E RL +  +  TQ++  +    +  KD +  TV   +  +   ++     ++  +  +  
Sbjct: 271 ERRLELGQREHTQLLQQS----SSQKDEILQTVKEEQSRLEQGLSEHQRHLNAERQRLQE 326

Query: 148 SVEKTKSVVSGSINTVLGSRMMQLVSSGVENALTKSELLVEQYLPLTEEELEKEAKKVEG 207
            +++T+  +S  I  +L     Q  SS +  +L    + +EQ + +T+EE E   ++   
Sbjct: 327 QLKQTEQNISSRIQKLLQDNQRQKKSSEILKSLENERIRMEQLMSITQEETESLRRRD-- 384

Query: 208 FDLVQKPSYYVRLGSLSTKLHSRAY--------QQALSRVKEAKQKSQQTIS 251
              V      +   S   +L   AY        QQA S + E  ++ QQ +S
Sbjct: 385 ---VASAMQQMLTESCKNRLIQMAYESQRQNLVQQACSSMAEMDERFQQILS 433


>gi|53729361 leucine rich repeat and sterile alpha motif containing
           1 [Homo sapiens]
          Length = 723

 Score = 33.5 bits (75), Expect = 0.39
 Identities = 36/172 (20%), Positives = 72/172 (41%), Gaps = 20/172 (11%)

Query: 91  EERLPILNQPSTQIVANAKGAVTGAKDAVTTTVTGAKDSVASTITGV---MDKTKGAVTG 147
           E RL +  +  TQ++  +    +  KD +  TV   +  +   ++     ++  +  +  
Sbjct: 271 ERRLELGQREHTQLLQQS----SSQKDEILQTVKEEQSRLEQGLSEHQRHLNAERQRLQE 326

Query: 148 SVEKTKSVVSGSINTVLGSRMMQLVSSGVENALTKSELLVEQYLPLTEEELEKEAKKVEG 207
            +++T+  +S  I  +L     Q  SS +  +L    + +EQ + +T+EE E   ++   
Sbjct: 327 QLKQTEQNISSRIQKLLQDNQRQKKSSEILKSLENERIRMEQLMSITQEETESLRRRD-- 384

Query: 208 FDLVQKPSYYVRLGSLSTKLHSRAY--------QQALSRVKEAKQKSQQTIS 251
              V      +   S   +L   AY        QQA S + E  ++ QQ +S
Sbjct: 385 ---VASAMQQMLTESCKNRLIQMAYESQRQNLVQQACSSMAEMDERFQQILS 433


>gi|53729359 leucine rich repeat and sterile alpha motif containing
           1 [Homo sapiens]
          Length = 723

 Score = 33.5 bits (75), Expect = 0.39
 Identities = 36/172 (20%), Positives = 72/172 (41%), Gaps = 20/172 (11%)

Query: 91  EERLPILNQPSTQIVANAKGAVTGAKDAVTTTVTGAKDSVASTITGV---MDKTKGAVTG 147
           E RL +  +  TQ++  +    +  KD +  TV   +  +   ++     ++  +  +  
Sbjct: 271 ERRLELGQREHTQLLQQS----SSQKDEILQTVKEEQSRLEQGLSEHQRHLNAERQRLQE 326

Query: 148 SVEKTKSVVSGSINTVLGSRMMQLVSSGVENALTKSELLVEQYLPLTEEELEKEAKKVEG 207
            +++T+  +S  I  +L     Q  SS +  +L    + +EQ + +T+EE E   ++   
Sbjct: 327 QLKQTEQNISSRIQKLLQDNQRQKKSSEILKSLENERIRMEQLMSITQEETESLRRRD-- 384

Query: 208 FDLVQKPSYYVRLGSLSTKLHSRAY--------QQALSRVKEAKQKSQQTIS 251
              V      +   S   +L   AY        QQA S + E  ++ QQ +S
Sbjct: 385 ---VASAMQQMLTESCKNRLIQMAYESQRQNLVQQACSSMAEMDERFQQILS 433


>gi|24308303 SH3-binding domain protein 5-like [Homo sapiens]
          Length = 393

 Score = 33.1 bits (74), Expect = 0.51
 Identities = 21/68 (30%), Positives = 36/68 (52%), Gaps = 2/68 (2%)

Query: 220 LGSLSTKLHSRAYQQALSRVKEAKQKSQQTISQLHSTVHLIEFARKNVYSANQKIQDAQD 279
           LGS   K  +R Y +A    KEA+Q++Q+   +    V +   AR+ V+ A Q +   ++
Sbjct: 106 LGSCIEK--ARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKN 163

Query: 280 KLYLSWVE 287
           +L  +W E
Sbjct: 164 RLDPTWQE 171


>gi|118498356 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 32.3 bits (72), Expect = 0.87
 Identities = 50/268 (18%), Positives = 109/268 (40%), Gaps = 15/268 (5%)

Query: 137 VMDKTKGAVTGSVEKTKSVVSGSINTVLGSRMMQLVSSGVENALTKSELLVEQYLPLTEE 196
           +++    A+   V+K +++VS   N  +  +M + +    E   T  ELL    + +  +
Sbjct: 702 ILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATK 761

Query: 197 ELEKEAKKVEGF-------DLVQKPSYYVRLGSLSTKLHSRAYQQ--ALSRVKEAKQKSQ 247
           E E  A + E         DL  K +  V   SL  +L    +++   +  V+E  +   
Sbjct: 762 EEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAEL 821

Query: 248 QTISQLHSTVHLIEFARKNVYS--ANQKIQDAQDKLYLSWVEWKRSIGYDDTDESHCAEH 305
             ++    TV  ++   K +     N +++ AQ     S V+  +++     ++ +  + 
Sbjct: 822 LKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKA 881

Query: 306 I---ESRTLAIARNLTQQLQTTCHTLLSNIQGVPQNIQDQAKHMGVMAGDIYSVFRNAAS 362
           +   + + LA      Q LQ    +L +++Q V Q+   +A        ++  V +   +
Sbjct: 882 VLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFE-ELEIVLKEKEN 940

Query: 363 FKEVSDSLLTSSKGQLQKMKESLDDVMD 390
             +  +++L   +  L    + L DV D
Sbjct: 941 ELKRLEAMLKERESDLSSKTQLLQDVQD 968


>gi|118498368 kinectin 1 isoform c [Homo sapiens]
          Length = 1300

 Score = 32.3 bits (72), Expect = 0.87
 Identities = 50/268 (18%), Positives = 109/268 (40%), Gaps = 15/268 (5%)

Query: 137 VMDKTKGAVTGSVEKTKSVVSGSINTVLGSRMMQLVSSGVENALTKSELLVEQYLPLTEE 196
           +++    A+   V+K +++VS   N  +  +M + +    E   T  ELL    + +  +
Sbjct: 702 ILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATK 761

Query: 197 ELEKEAKKVEGF-------DLVQKPSYYVRLGSLSTKLHSRAYQQ--ALSRVKEAKQKSQ 247
           E E  A + E         DL  K +  V   SL  +L    +++   +  V+E  +   
Sbjct: 762 EEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAEL 821

Query: 248 QTISQLHSTVHLIEFARKNVYS--ANQKIQDAQDKLYLSWVEWKRSIGYDDTDESHCAEH 305
             ++    TV  ++   K +     N +++ AQ     S V+  +++     ++ +  + 
Sbjct: 822 LKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKA 881

Query: 306 I---ESRTLAIARNLTQQLQTTCHTLLSNIQGVPQNIQDQAKHMGVMAGDIYSVFRNAAS 362
           +   + + LA      Q LQ    +L +++Q V Q+   +A        ++  V +   +
Sbjct: 882 VLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFE-ELEIVLKEKEN 940

Query: 363 FKEVSDSLLTSSKGQLQKMKESLDDVMD 390
             +  +++L   +  L    + L DV D
Sbjct: 941 ELKRLEAMLKERESDLSSKTQLLQDVQD 968


>gi|33620775 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 32.3 bits (72), Expect = 0.87
 Identities = 50/268 (18%), Positives = 109/268 (40%), Gaps = 15/268 (5%)

Query: 137 VMDKTKGAVTGSVEKTKSVVSGSINTVLGSRMMQLVSSGVENALTKSELLVEQYLPLTEE 196
           +++    A+   V+K +++VS   N  +  +M + +    E   T  ELL    + +  +
Sbjct: 702 ILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATK 761

Query: 197 ELEKEAKKVEGF-------DLVQKPSYYVRLGSLSTKLHSRAYQQ--ALSRVKEAKQKSQ 247
           E E  A + E         DL  K +  V   SL  +L    +++   +  V+E  +   
Sbjct: 762 EEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAEL 821

Query: 248 QTISQLHSTVHLIEFARKNVYS--ANQKIQDAQDKLYLSWVEWKRSIGYDDTDESHCAEH 305
             ++    TV  ++   K +     N +++ AQ     S V+  +++     ++ +  + 
Sbjct: 822 LKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKA 881

Query: 306 I---ESRTLAIARNLTQQLQTTCHTLLSNIQGVPQNIQDQAKHMGVMAGDIYSVFRNAAS 362
           +   + + LA      Q LQ    +L +++Q V Q+   +A        ++  V +   +
Sbjct: 882 VLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFE-ELEIVLKEKEN 940

Query: 363 FKEVSDSLLTSSKGQLQKMKESLDDVMD 390
             +  +++L   +  L    + L DV D
Sbjct: 941 ELKRLEAMLKERESDLSSKTQLLQDVQD 968


>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
          Length = 1094

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 45/222 (20%), Positives = 83/222 (37%), Gaps = 24/222 (10%)

Query: 193 LTEEELEKEAKKVEGFDLVQKPSYYVRLGSLSTKLHSRAYQQALSRVKEAKQKSQQTISQ 252
           L EEEL  + +K+      Q         SL T      ++      K++K +SQ  + +
Sbjct: 555 LQEEELHSKEEKLRDIKSHQADLELEVKNSLDT-----IHRLESELKKQSKIQSQMKVEK 609

Query: 253 LHSTVHLIEFARKNVYSANQKIQDAQDKLYLSWVEW------------KRSIGYDDTDES 300
            H    + E  +       + ++  +    LS +              K+++  D +D +
Sbjct: 610 AHLEEEIAELKKSQAQDKAKLLEMQESIKDLSAIRADLANKLAEEERAKKAVLKDLSDLT 669

Query: 301 HCAEHIESRTLAIARNLTQQL---QTTCHTLLSNIQGVP----QNIQDQAKHMGVMAGDI 353
             A+  +  T  I   L  +    Q     L S++Q V     QNIQ+  KH      + 
Sbjct: 670 AQAKSRDEETATIITQLKLERDVHQRELKDLTSSLQSVKTKHEQNIQELMKHFKKEKSEA 729

Query: 354 YSVFRNAASFKEVSDSLLTSSKGQLQKMKESLDDVMDYLVNN 395
            +  R   +      ++    +GQL+K+K   D + + L  N
Sbjct: 730 ENHIRTLKAESLEEKNMAKIHRGQLEKLKSQCDRLTEELTQN 771


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 48/266 (18%), Positives = 112/266 (42%), Gaps = 35/266 (13%)

Query: 173  SSGVENALTKSELLVEQYLPLTEEELEKEAKKVEGFDLVQKPSYYVRLGSLSTKLHSRAY 232
            S    + LTK    +E  L  T+E L++E +        QK S   +L  +  + +S  +
Sbjct: 1292 SDSKSSKLTKDFSALESQLQDTQELLQEENR--------QKLSLSTKLKQVEDEKNS--F 1341

Query: 233  QQALSRVKEAKQKSQQTISQLHSTVHLIEFARKNVYSANQKIQDAQDKLY-----LSWVE 287
            ++ L   +EAK   ++ I+ LH+ V  ++   ++     +  ++ + KL      LS   
Sbjct: 1342 REQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRH 1401

Query: 288  WKRSIGYDDTDESHCAEHIESRTLAIARNLTQQLQTTCHTLLSNIQGVPQNIQDQAKHMG 347
             ++   YD  +++      E   L +  +L  Q Q+ C            N++ + K   
Sbjct: 1402 EEKVAAYDKLEKTKTRLQQELDDLLV--DLDHQRQSAC------------NLEKKQKKFD 1447

Query: 348  VMAGDIYSVFRNAASFKEVSDSLLTSSKGQLQKMKESLDDVMDYLVNNTPLNWLVGPFYP 407
             +  +  ++    A  ++ +++     + +   +  +L++ M+       L  L   F  
Sbjct: 1448 QLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAME---QKAELERLNKQFRT 1504

Query: 408  QLTESQNAQDQGAEMDKSSQETQRSE 433
            ++ +  +++D   ++ KS  E ++S+
Sbjct: 1505 EMEDLMSSKD---DVGKSVHELEKSK 1527


>gi|118498362 kinectin 1 isoform b [Homo sapiens]
          Length = 1306

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 53/263 (20%), Positives = 103/263 (39%), Gaps = 28/263 (10%)

Query: 137 VMDKTKGAVTGSVEKTKSVVSGSINTVLGSRMMQLVSSGVENALTKSELLVEQYLPLTEE 196
           +++    A+   V+K +++VS   N  +  +M + +    E   T  ELL    + +  +
Sbjct: 702 ILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATK 761

Query: 197 ELEKEAKKVEGF-------DLVQKPSYYVRLGSLSTKLHSRAYQQ--ALSRVKEAKQKSQ 247
           E E  A + E         DL  K +  V   SL  +L    +++   +  V+E  +   
Sbjct: 762 EEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAEL 821

Query: 248 QTISQLHSTVHLIEFARKNVYSANQKIQDAQDKLYLSWVEWKRSIGYDDTDESHCAEHIE 307
             ++    TV L         S   K+Q+ Q+ L       K      +T ++   E  +
Sbjct: 822 LKVANKEKTVQL---------SITSKVQELQNLL-------KGKEEQMNTMKAVLEE--K 863

Query: 308 SRTLAIARNLTQQLQTTCHTLLSNIQGVPQNIQDQAKHMGVMAGDIYSVFRNAASFKEVS 367
            + LA      Q LQ    +L +++Q V Q+   +A        ++  V +   +  +  
Sbjct: 864 EKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFE-ELEIVLKEKENELKRL 922

Query: 368 DSLLTSSKGQLQKMKESLDDVMD 390
           +++L   +  L    + L DV D
Sbjct: 923 EAMLKERESDLSSKTQLLQDVQD 945


>gi|25777650 small conductance calcium-activated potassium channel
           protein 3 isoform b [Homo sapiens]
          Length = 426

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 31/147 (21%), Positives = 64/147 (43%), Gaps = 12/147 (8%)

Query: 180 LTKSELLVEQYLPLTE--EELEKEAKKV--EGFDLVQKPSYYVRLGSLSTKLHSRAYQQA 235
           LTK+E  V  ++  T+  + ++  A  V  E + + +      ++     + H R + QA
Sbjct: 243 LTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQA 302

Query: 236 LSRVKEAKQKSQQTISQLHSTVHLIEFARKNVYSANQKIQDAQDKLYLSWVEWKRSIGYD 295
           + +++  K + ++   Q ++ V L +  +  +Y    ++ D  + L       ++ IG  
Sbjct: 303 IHQLRSVKMEQRKLSDQANTLVDLSKM-QNVMYDLITELNDRSEDL-------EKQIGSL 354

Query: 296 DTDESHCAEHIESRTLAIARNLTQQLQ 322
           ++   H      S  L IA  L QQ Q
Sbjct: 355 ESKLEHLTASFNSLPLLIADTLRQQQQ 381


>gi|116805330 small conductance calcium-activated potassium channel
           protein 3 isoform a [Homo sapiens]
          Length = 731

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 31/147 (21%), Positives = 64/147 (43%), Gaps = 12/147 (8%)

Query: 180 LTKSELLVEQYLPLTE--EELEKEAKKV--EGFDLVQKPSYYVRLGSLSTKLHSRAYQQA 235
           LTK+E  V  ++  T+  + ++  A  V  E + + +      ++     + H R + QA
Sbjct: 548 LTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQA 607

Query: 236 LSRVKEAKQKSQQTISQLHSTVHLIEFARKNVYSANQKIQDAQDKLYLSWVEWKRSIGYD 295
           + +++  K + ++   Q ++ V L +  +  +Y    ++ D  + L       ++ IG  
Sbjct: 608 IHQLRSVKMEQRKLSDQANTLVDLSKM-QNVMYDLITELNDRSEDL-------EKQIGSL 659

Query: 296 DTDESHCAEHIESRTLAIARNLTQQLQ 322
           ++   H      S  L IA  L QQ Q
Sbjct: 660 ESKLEHLTASFNSLPLLIADTLRQQQQ 686


>gi|89886447 nitric oxide synthase trafficker isoform 2 [Homo
           sapiens]
          Length = 506

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 58/253 (22%), Positives = 97/253 (38%), Gaps = 51/253 (20%)

Query: 40  YPYLKSVCEMAENGVKTITSVAMTSALPIIQKLEPQIAVANTYACKGLDRIEERLP--IL 97
           Y  LK   +  EN  K +TSV         Q+   +I+ A     KGL ++  +L   + 
Sbjct: 14  YKNLKEFSQNGENFCKQVTSVLQ-------QRANLEISYA-----KGLQKLASKLSKALQ 61

Query: 98  NQPSTQIVANAKGAVTGAKDAVTTTVTGAK----DSVAST--ITGVMDKTKGAVTGSVEK 151
           N   + + +    A  G K          K    +++  T  +  V +K + ++   VEK
Sbjct: 62  NTRKSCVSSAWAWASEGMKSTADLHQKLGKAIELEAIKPTYQVLNVQEKKRKSLDNEVEK 121

Query: 152 TKSVVSGSINTVLGSR------------MMQLVSSGVENALTKSELLVEQYLPLTEEELE 199
           T ++V  + N  + ++            + QLV S  ++   K +  +   L  + E+LE
Sbjct: 122 TANLVISNWNQQIKAKKKLMVSTKKHEALFQLVESSKQSMTEKEKRKLLNKLTKSTEKLE 181

Query: 200 KEAKKVEGFDLVQKPSYYVRLGSLSTKLHSRAYQQALSRVKE--------AKQKSQ---- 247
           KE    E +       Y  RL   +T      YQ  L   KE          Q SQ    
Sbjct: 182 KED---ENYYQKNMAGYSTRLKWENTL--ENCYQSILELEKERIQLLCNNLNQYSQHISL 236

Query: 248 --QTISQLHSTVH 258
             QT++  H+ +H
Sbjct: 237 FGQTLTTCHTQIH 249


>gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens]
          Length = 2540

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 46/202 (22%), Positives = 77/202 (38%), Gaps = 11/202 (5%)

Query: 94   LPILNQPSTQIVANAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTK 153
            LP +N  S     + K     ++ +V ++V  A +++ +T T V+       + S     
Sbjct: 1356 LPNVNSDSVH-TKSEKNFQAVSQGSVPSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGS 1414

Query: 154  SVVSGSINTVLGSRMMQLVSSG--VENALTKSELLVEQYLPLTEEELEKEAKKVEGFDLV 211
             V+S   NT+L S   + VSS    +    K E  V    P+T     K    V+     
Sbjct: 1415 EVISSLSNTILASTSSECVSSKSVSQPVAQKQECKVSTTAPVTLAS-SKTGSVVQPSSGF 1473

Query: 212  QKPSYYVRLGSLSTKLHSRAYQQALSRVKEAKQKSQQTIS---QLHSTVHLIEFARKNVY 268
               + ++ L      L +  Y+ + +   E      QT+S    L STV      + N  
Sbjct: 1474 SGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASLPLDSTVICSTINKANSV 1533

Query: 269  SANQKIQDAQ----DKLYLSWV 286
               Q  Q +Q     KL  +W+
Sbjct: 1534 GNGQASQTSQPNYHTKLKKAWL 1555


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.124    0.336 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,675,969
Number of Sequences: 37866
Number of extensions: 528575
Number of successful extensions: 2056
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 80
Number of HSP's that attempted gapping in prelim test: 1775
Number of HSP's gapped (non-prelim): 303
length of query: 437
length of database: 18,247,518
effective HSP length: 105
effective length of query: 332
effective length of database: 14,271,588
effective search space: 4738167216
effective search space used: 4738167216
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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