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Search of human proteins with 34098976
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|34098976 marapsin 2 [Homo sapiens]
(326 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|34098976 marapsin 2 [Homo sapiens] 684 0.0
gi|13994276 marapsin [Homo sapiens] 206 2e-53
gi|148806900 epidermis-specific serine protease-like protein [Ho... 189 4e-48
gi|4506153 prostasin preproprotein [Homo sapiens] 185 4e-47
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens] 185 5e-47
gi|4503627 coagulation factor XI precursor [Homo sapiens] 181 8e-46
gi|117956391 protease, serine, 33 [Homo sapiens] 181 1e-45
gi|11545839 protease, serine, 22 [Homo sapiens] 180 1e-45
gi|170932492 transmembrane protease, serine 5 [Homo sapiens] 180 2e-45
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 177 1e-44
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa... 176 2e-44
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa... 176 2e-44
gi|116256363 transmembrane protease, serine 13 [Homo sapiens] 176 2e-44
gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 174 1e-43
gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens] 174 1e-43
gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo ... 174 1e-43
gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo ... 174 1e-43
gi|21614531 testisin isoform 2 [Homo sapiens] 172 3e-43
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 171 1e-42
gi|5803197 testisin isoform 1 [Homo sapiens] 170 1e-42
gi|58218970 protease, serine, 36 [Homo sapiens] 169 2e-42
gi|205360905 testis-specific serine protease 1 [Homo sapiens] 168 7e-42
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens] 164 1e-40
gi|4505881 plasminogen [Homo sapiens] 162 5e-40
gi|68508970 tryptase beta 2 precursor [Homo sapiens] 162 5e-40
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa... 161 8e-40
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap... 161 8e-40
gi|33695155 hepsin [Homo sapiens] 160 2e-39
gi|4504481 hepsin [Homo sapiens] 160 2e-39
gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens] 158 5e-39
>gi|34098976 marapsin 2 [Homo sapiens]
Length = 326
Score = 684 bits (1764), Expect = 0.0
Identities = 326/326 (100%), Positives = 326/326 (100%)
Query: 1 MAAPASVMGPLGPSALGLLLLLLVVAPPRVAALVHRQPENQGISLTGSVACGRPSMEGKI 60
MAAPASVMGPLGPSALGLLLLLLVVAPPRVAALVHRQPENQGISLTGSVACGRPSMEGKI
Sbjct: 1 MAAPASVMGPLGPSALGLLLLLLVVAPPRVAALVHRQPENQGISLTGSVACGRPSMEGKI 60
Query: 61 LGGVPAPERKWPWQVSVHYAGLHVCGGSILNEYWVLSAAHCFHRDKNIKIYDMYVGLVNL 120
LGGVPAPERKWPWQVSVHYAGLHVCGGSILNEYWVLSAAHCFHRDKNIKIYDMYVGLVNL
Sbjct: 61 LGGVPAPERKWPWQVSVHYAGLHVCGGSILNEYWVLSAAHCFHRDKNIKIYDMYVGLVNL 120
Query: 121 RVAGNHTQWYEVNRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLATPEVNLTS 180
RVAGNHTQWYEVNRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLATPEVNLTS
Sbjct: 121 RVAGNHTQWYEVNRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLATPEVNLTS 180
Query: 181 ANCWATGWGLVSKQGETSDELQEMQLPLILEPWCHLLYGHMSYIMPDMLCAGDILNAKTV 240
ANCWATGWGLVSKQGETSDELQEMQLPLILEPWCHLLYGHMSYIMPDMLCAGDILNAKTV
Sbjct: 181 ANCWATGWGLVSKQGETSDELQEMQLPLILEPWCHLLYGHMSYIMPDMLCAGDILNAKTV 240
Query: 241 CEGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSKWICDNIEITPTPAQ 300
CEGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSKWICDNIEITPTPAQ
Sbjct: 241 CEGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSKWICDNIEITPTPAQ 300
Query: 301 PAPALSPALGPTLSVLMAMLAGWSVL 326
PAPALSPALGPTLSVLMAMLAGWSVL
Sbjct: 301 PAPALSPALGPTLSVLMAMLAGWSVL 326
>gi|13994276 marapsin [Homo sapiens]
Length = 290
Score = 206 bits (524), Expect = 2e-53
Identities = 115/286 (40%), Positives = 152/286 (53%), Gaps = 27/286 (9%)
Query: 13 PSALGLLLLLLVVAPPRVAALVHRQPENQGISLTGSVACGRPSMEGKILGGVPAPERKWP 72
P+A+ LLLLL + AA ACGRP M +++GG E +WP
Sbjct: 4 PAAVPLLLLLCFGSQRAKAA----------------TACGRPRMLNRMVGGQDTQEGEWP 47
Query: 73 WQVSVHYAGLHVCGGSILNEYWVLSAAHCFHRDKNIKIYDMYVGLVNLRVAGNHTQWYEV 132
WQVS+ G H CGGS++ E WVL+AAHCF +Y + +G L G H + V
Sbjct: 48 WQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYARV 107
Query: 133 NRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLATPEVNL-TSANCWATGWGLV 191
+V +P Y+ DVALV+L+ + F+ +LPVCL P V T NCW TGWG
Sbjct: 108 RQVESNPLYQ-GTASSADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSP 166
Query: 192 SKQGETSDE--LQEMQLPLILEPWCHLLYG-------HMSYIMPDMLCAGDILNAKTVCE 242
S++ + LQ++ +P+I P C+LLY I DMLCAG K C+
Sbjct: 167 SEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACK 226
Query: 243 GDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSKWI 288
GDSGGPLVC +SWLQ G++SWG GC+ PGVY V+ WI
Sbjct: 227 GDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWI 272
>gi|148806900 epidermis-specific serine protease-like protein [Homo
sapiens]
Length = 328
Score = 189 bits (479), Expect = 4e-48
Identities = 93/255 (36%), Positives = 144/255 (56%), Gaps = 16/255 (6%)
Query: 45 LTGSVACGRPSMEGKILGGVPAPERKWPWQVSVHYAGLHVCGGSILNEYWVLSAAHCFHR 104
L G CG+P +++GG A +WPWQVS+H+ +CGGS+++E +L+AAHC
Sbjct: 13 LLGISVCGQPVYSSRVVGGQDAAAGRWPWQVSLHFDHNFICGGSLVSERLILTAAHCIQP 72
Query: 105 DKNIKIYDMYVGLVNLRVAGNHTQWYEVNRVILHPTYEMYHPIGGDVALVQLKTRIVFSE 164
Y +++G + + + ++Y V+++++HP Y+ DVAL++L +++ F+
Sbjct: 73 TWTTFSYTVWLGSITVGDSRKRVKYY-VSKIVIHPKYQ---DTTADVALLKLSSQVTFTS 128
Query: 165 SVLPVCLATPEVNLT-SANCWATGWGLVSKQGETS--DELQEMQLPLILEPWCHLLYGHM 221
++LP+CL + L CW TGWG V + + LQE ++P+I C LY +
Sbjct: 129 AILPICLPSVTKQLAIPPFCWVTGWGKVKESSDRDYHSALQEAEVPIIDRQACEQLYNPI 188
Query: 222 SYIMP--------DMLCAGDILNAKTVCEGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPL 273
+P D +CAGD N K C+GDSGGPL C + W+Q G+VSWG C L
Sbjct: 189 GIFLPALEPVIKEDKICAGDTQNMKDSCKGDSGGPLSCHIDGVWIQTGVVSWGLECGKSL 248
Query: 274 YPGVYASVSYFSKWI 288
PGVY +V Y+ KWI
Sbjct: 249 -PGVYTNVIYYQKWI 262
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 185 bits (470), Expect = 4e-47
Identities = 106/298 (35%), Positives = 152/298 (51%), Gaps = 22/298 (7%)
Query: 9 GPLGPSALGLLLLLLVVAPPRVAALVHRQPENQGISLTGSVACGRPSMEGKILGGVPAPE 68
G LGP LG + +LL + R G G+ A + + +I GG A
Sbjct: 5 GVLGPGQLGAVAILLYLGLLR-----------SGTGAEGAEAPCGVAPQARITGGSSAVA 53
Query: 69 RKWPWQVSVHYAGLHVCGGSILNEYWVLSAAHCFHRDKNIKIYDMYVGLVNLRVAGNHTQ 128
+WPWQVS+ Y G+HVCGGS+++E WVLSAAHCF + + + Y++ +G L +
Sbjct: 54 GQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAK 113
Query: 129 WYEVNRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLATPEVNLTSA-NCWATG 187
+ +I HP+Y + GD+AL+QL I FS + P+CL + + +C TG
Sbjct: 114 VSTLKDIIPHPSY-LQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTG 172
Query: 188 WGLVSKQGE--TSDELQEMQLPLILEPWCHLLYG------HMSYIMPDMLCAGDILNAKT 239
WG V+ T LQ++++PLI C+ LY ++ DM+CAG + K
Sbjct: 173 WGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKD 232
Query: 240 VCEGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSKWICDNI-EITP 296
C+GDSGGPL C W GIVSWG C PGVY S ++ WI + E+ P
Sbjct: 233 ACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQP 290
>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
Length = 321
Score = 185 bits (469), Expect = 5e-47
Identities = 119/324 (36%), Positives = 167/324 (51%), Gaps = 34/324 (10%)
Query: 15 ALGLLLLLLVVAPPRVAALVHRQPENQGISL-TGSVACGRPSME---GKILGGVPAPERK 70
ALG LLL++A P G+SL T CGRP + G+I+GG AP
Sbjct: 2 ALGACGLLLLLAVP-------------GVSLRTLQPGCGRPQVSDAGGRIVGGHAAPAGA 48
Query: 71 WPWQVSVHYAGLHVCGGSILNEYWVLSAAHCFHRDKNIKIYDMYVGLVNLRVAGNHTQWY 130
WPWQ S+ +HVCGGS+L+ WVL+AAHCF N Y +++G + + ++ + +
Sbjct: 49 WPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHLGELEITLSPHFST-- 106
Query: 131 EVNRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLATPEVN---LTSANCWATG 187
V ++ILH + GD+ALV+L + S +LPVCL PE + CW TG
Sbjct: 107 -VRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCL--PEASDDFCPGIRCWVTG 163
Query: 188 WGLVSKQGETSD---ELQEMQLPLILEPWCHLLYGHM--SYIMPDMLCAGDILNAKTVCE 242
WG +++GE L+E+++ ++ C Y S + PDMLCA +A C+
Sbjct: 164 WGY-TREGEPLPPPYSLREVKVSVVDTETCRRDYPGPGGSILQPDMLCARGPGDA---CQ 219
Query: 243 GDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSKWICDNIEITPTPAQPA 302
DSGGPLVC+ N +W+Q GIVSWG GC P PGVY V + WI +I +
Sbjct: 220 DDSGGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSESGY 279
Query: 303 PALSPALGPTLSVLMAMLAGWSVL 326
P L G L L +L +L
Sbjct: 280 PRLPLLAGFFLPGLFLLLVSCVLL 303
>gi|4503627 coagulation factor XI precursor [Homo sapiens]
Length = 625
Score = 181 bits (459), Expect = 8e-46
Identities = 89/240 (37%), Positives = 139/240 (57%), Gaps = 8/240 (3%)
Query: 59 KILGGVPAPERKWPWQVSVHYAG---LHVCGGSILNEYWVLSAAHCFHRDKNIKIYDMYV 115
+I+GG + +WPWQV++H H+CGGSI+ W+L+AAHCF+ ++ KI +Y
Sbjct: 387 RIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYS 446
Query: 116 GLVNLRVAGNHTQWYEVNRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLATP- 174
G++N T ++ V +I+H Y+M G D+AL++L+T + +++S P+CL +
Sbjct: 447 GILNQSEIKEDTSFFGVQEIIIHDQYKMAES-GYDIALLKLETTVNYTDSQRPICLPSKG 505
Query: 175 EVNLTSANCWATGWGLVSKQGETSDELQEMQLPLILEPWCHLLY-GHMSYIMPDMLCAGD 233
+ N+ +CW TGWG + + + LQ+ ++PL+ C Y GH I M+CAG
Sbjct: 506 DRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHK--ITHKMICAGY 563
Query: 234 ILNAKTVCEGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSKWICDNIE 293
K C+GDSGGPL C+ N W +GI SWG GC+ PGVY +V + WI + +
Sbjct: 564 REGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQ 623
>gi|117956391 protease, serine, 33 [Homo sapiens]
Length = 280
Score = 181 bits (458), Expect = 1e-45
Identities = 111/289 (38%), Positives = 150/289 (51%), Gaps = 29/289 (10%)
Query: 12 GPSALGLLLLLLVVAPPRVAALVHRQPENQGISLTGSVACGRPSMEGKILGGVPAPERKW 71
G S L +LLLL++ A G S ACG+P M +I+GG + +W
Sbjct: 3 GVSCLQVLLLLVLGAA--------------GTQGRKSAACGQPRMSSRIVGGRDGRDGEW 48
Query: 72 PWQVSVHYAGLHVCGGSILNEYWVLSAAHCFHRDKNIKIYDMYVGLVNLRVAGNHTQWYE 131
PWQ S+ + G HVCGGS++ WVL+AAHCF R Y + +G + L T
Sbjct: 49 PWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVP 108
Query: 132 VNRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLATPEVNLTSAN-CWATGWGL 190
V RV+L P Y GD+AL+QL+ + S V PVCL P C TGWG
Sbjct: 109 VRRVLLPPDYS-EDGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGS 167
Query: 191 VSKQGETSDE---LQEMQLPLILEPWCHLLYGHMS--------YIMPDMLCAGDILNAKT 239
+ + G E LQ +++PL+ C LY H+ ++P LCAG K
Sbjct: 168 L-RPGVPLPEWRPLQGVRVPLLDSRTCDGLY-HVGADVPQAERIVLPGSLCAGYPQGHKD 225
Query: 240 VCEGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSKWI 288
C+GDSGGPL C + SW+ +G+VSWG+GC+ P PGVY SV+ +S WI
Sbjct: 226 ACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWI 274
>gi|11545839 protease, serine, 22 [Homo sapiens]
Length = 317
Score = 180 bits (457), Expect = 1e-45
Identities = 103/287 (35%), Positives = 150/287 (52%), Gaps = 20/287 (6%)
Query: 11 LGPSALGLLLLLLVVAPPRV--AALVHRQPENQGISLTGSVACGRPSMEGKILGGVPAPE 68
LG LG LL++A + AA + P ACG+P +++GG + +
Sbjct: 10 LGGGCLGTFTSLLLLASTAILNAARIPVPP-----------ACGKPQQLNRVVGGEDSTD 58
Query: 69 RKWPWQVSVHYAGLHVCGGSILNEYWVLSAAHCFHRDKNIK-IYDMYVGLVNLRVAGNHT 127
+WPW VS+ G H C GS+L WV++AAHCF + N ++ + +G L G+ +
Sbjct: 59 SEWPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRS 118
Query: 128 QWYEVNRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLATPEVNLT-SANCWAT 186
Q V V HP Y D+ALV+L+ I FSE VLP+CL ++L + +CW +
Sbjct: 119 QKVGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWIS 178
Query: 187 GWGLVSKQGETS--DELQEMQLPLILEPWCHLLYGH---MSYIMPDMLCAGDILNAKTVC 241
GWG + LQ++++P+I C LY I DMLCAG + + C
Sbjct: 179 GWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERDAC 238
Query: 242 EGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSKWI 288
GDSGGPL+C+ + +WL GI+SWG GC+ PGVY S+S W+
Sbjct: 239 LGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWV 285
>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
Length = 457
Score = 180 bits (456), Expect = 2e-45
Identities = 106/277 (38%), Positives = 147/277 (53%), Gaps = 14/277 (5%)
Query: 28 PRVAALVHR--QPEN-----QGISLTGSVACGRPSMEGKILGGVPAPERKWPWQVSVHYA 80
PR+ + QP N Q +SL S CG + +I+GG +WPWQ SV
Sbjct: 180 PRLGGFLEEAWQPRNNCTSGQVVSLRCS-ECGARPLASRIVGGQSVAPGRWPWQASVALG 238
Query: 81 GLHVCGGSILNEYWVLSAAHCFH--RDKNIKIYDMYVGLVNLRVAGNHTQWYEVNRVILH 138
H CGGS+L WV++AAHC H R + + ++ GLV+ H Q V R+I H
Sbjct: 239 FRHTCGGSVLAPRWVVTAAHCMHSFRLARLSSWRVHAGLVSHSAVRPH-QGALVERIIPH 297
Query: 139 PTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLATPEVNLTSAN-CWATGWGLVSKQGE- 196
P Y + DVAL++L+T + FS++V VCL E + + CW +GWG
Sbjct: 298 PLYSAQNH-DYDVALLRLQTALNFSDTVGAVCLPAKEQHFPKGSRCWVSGWGHTHPSHTY 356
Query: 197 TSDELQEMQLPLILEPWCHLLYGHMSYIMPDMLCAGDILNAKTVCEGDSGGPLVCEFNRS 256
+SD LQ+ +PL C+ + + P MLCAG + C+GDSGGPLVC +
Sbjct: 357 SSDMLQDTVVPLFSTQLCNSSCVYSGALTPRMLCAGYLDGRADACQGDSGGPLVCPDGDT 416
Query: 257 WLQIGIVSWGRGCSNPLYPGVYASVSYFSKWICDNIE 293
W +G+VSWGRGC+ P +PGVYA V+ F WI D +
Sbjct: 417 WRLVGVVSWGRGCAEPNHPGVYAKVAEFLDWIHDTAQ 453
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 177 bits (449), Expect = 1e-44
Identities = 88/246 (35%), Positives = 137/246 (55%), Gaps = 6/246 (2%)
Query: 59 KILGGVPAPERKWPWQVSVHY---AGLHVCGGSILNEYWVLSAAHCFHRDKNIKIYDMYV 115
+I+GG + +WPWQVS+ A H+CGGS++ WVL+AAHCF ++ +Y
Sbjct: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449
Query: 116 GLVNLRVAGNHTQWYEVNRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLATP- 174
G++NL T + ++ +I+H Y++ D+AL++L+ + ++E P+CL +
Sbjct: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPICLPSKG 508
Query: 175 EVNLTSANCWATGWGLVSKQGETSDELQEMQLPLILEPWCHLLYGHMSYIMPDMLCAGDI 234
+ + NCW TGWG ++GE + LQ++ +PL+ C Y I M+CAG
Sbjct: 509 DTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYK-ITQRMVCAGYK 567
Query: 235 LNAKTVCEGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSKWICDNIEI 294
K C+GDSGGPLVC+ N W +GI SWG GC+ PGVY V+ + WI + +
Sbjct: 568 EGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627
Query: 295 TPTPAQ 300
+ AQ
Sbjct: 628 SDGKAQ 633
>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
sapiens]
Length = 529
Score = 176 bits (447), Expect = 2e-44
Identities = 93/245 (37%), Positives = 136/245 (55%), Gaps = 7/245 (2%)
Query: 49 VACG---RPSMEGKILGGVPAPERKWPWQVSVHYAGLHVCGGSILNEYWVLSAAHCFHRD 105
+ACG S + +I+GG A WPWQVS+H +HVCGGSI+ W+++AAHC +
Sbjct: 279 IACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKP 338
Query: 106 KNIKIY-DMYVGLVNLRVAGNHTQWYEVNRVILHPTYEMYHPIGGDVALVQLKTRIVFSE 164
N + + G++ + Y+V +VI HP Y+ D+AL++L+ + F++
Sbjct: 339 LNNPWHWTAFAGILRQSFMF-YGAGYQVEKVISHPNYDSKTK-NNDIALMKLQKPLTFND 396
Query: 165 SVLPVCLATPEVNLTSAN-CWATGWGLVSKQGETSDELQEMQLPLILEPWCHLLYGHMSY 223
V PVCL P + L CW +GWG ++G+TS+ L ++ LI C+ Y + +
Sbjct: 397 LVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNL 456
Query: 224 IMPDMLCAGDILNAKTVCEGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSY 283
I P M+CAG + C+GDSGGPLV N W IG SWG GC+ PGVY +V
Sbjct: 457 ITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMV 516
Query: 284 FSKWI 288
F+ WI
Sbjct: 517 FTDWI 521
>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
sapiens]
Length = 492
Score = 176 bits (447), Expect = 2e-44
Identities = 93/245 (37%), Positives = 136/245 (55%), Gaps = 7/245 (2%)
Query: 49 VACG---RPSMEGKILGGVPAPERKWPWQVSVHYAGLHVCGGSILNEYWVLSAAHCFHRD 105
+ACG S + +I+GG A WPWQVS+H +HVCGGSI+ W+++AAHC +
Sbjct: 242 IACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKP 301
Query: 106 KNIKIY-DMYVGLVNLRVAGNHTQWYEVNRVILHPTYEMYHPIGGDVALVQLKTRIVFSE 164
N + + G++ + Y+V +VI HP Y+ D+AL++L+ + F++
Sbjct: 302 LNNPWHWTAFAGILRQSFMF-YGAGYQVEKVISHPNYDSKTK-NNDIALMKLQKPLTFND 359
Query: 165 SVLPVCLATPEVNLTSAN-CWATGWGLVSKQGETSDELQEMQLPLILEPWCHLLYGHMSY 223
V PVCL P + L CW +GWG ++G+TS+ L ++ LI C+ Y + +
Sbjct: 360 LVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNL 419
Query: 224 IMPDMLCAGDILNAKTVCEGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSY 283
I P M+CAG + C+GDSGGPLV N W IG SWG GC+ PGVY +V
Sbjct: 420 ITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMV 479
Query: 284 FSKWI 288
F+ WI
Sbjct: 480 FTDWI 484
>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
Length = 567
Score = 176 bits (447), Expect = 2e-44
Identities = 99/266 (37%), Positives = 145/266 (54%), Gaps = 11/266 (4%)
Query: 34 VHRQ--PENQGISLTGSVACGRPSMEGKILGGVPAPERKWPWQVSVHYAGLHVCGGSILN 91
+HR P + ISL S CG +M G+I+GG A + KWPWQVS+H+ H+CGG++++
Sbjct: 299 LHRSECPSQRYISLQCS-HCGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLID 357
Query: 92 EYWVLSAAHCFH--RDKNIKIYDMYVGLVNLRVAGNHTQWYEVNRVILHPTYEMYHPIGG 149
WVL+AAHCF R+K ++ + +Y G NL + +I++ Y
Sbjct: 358 AQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAAS---IAEIIINSNYTDEED-DY 413
Query: 150 DVALVQLKTRIVFSESVLPVCLATPEVNLT-SANCWATGWGLVSKQGE-TSDELQEMQLP 207
D+AL++L + S + P CL + + CW TG+G + + TS L+E+Q+
Sbjct: 414 DIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVN 473
Query: 208 LILEPWCHLLYGHMSYIMPDMLCAGDILNAKTVCEGDSGGPLVCEFNRSWLQIGIVSWGR 267
LI C+ + SY+ P M+CAGD+ + C+GDSGGPLVCE N W G+ SWG
Sbjct: 474 LIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGT 533
Query: 268 GCSNPLYPGVYASVSYFSKWICDNIE 293
GC PGVY V+ WI +E
Sbjct: 534 GCGQRNKPGVYTKVTEVLPWIYSKME 559
>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
Length = 811
Score = 174 bits (441), Expect = 1e-43
Identities = 95/244 (38%), Positives = 139/244 (56%), Gaps = 11/244 (4%)
Query: 51 CGRPSMEGKILGGVPAPERKWPWQVSVHYAGLHVCGGSILNEYWVLSAAHCFHRDK--NI 108
CG +I+GG + E +WPWQ S+ G H+CGG+++ + WV++AAHCF D +
Sbjct: 568 CGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMAST 627
Query: 109 KIYDMYVGLV--NLRVAGNHTQWYEVNRVILHPTYEMYHPIGGDVALVQLKTRIVFSESV 166
++ +++G V N R G + ++V+R++LHP Y DVAL+QL +V S +V
Sbjct: 628 VLWTVFLGKVWQNSRWPGEVS--FKVSRLLLHP-YHEEDSHDYDVALLQLDHPVVRSAAV 684
Query: 167 LPVCL-ATPEVNLTSANCWATGWGLVSKQGETSDELQEMQLPLILEPWCHLLYGHMSYIM 225
PVCL A +CW TGWG + + G S+ LQ++ + LI + C +Y + +
Sbjct: 685 RPVCLPARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYRYQ--VT 742
Query: 226 PDMLCAGDILNAKTVCEGDSGGPLVCE-FNRSWLQIGIVSWGRGCSNPLYPGVYASVSYF 284
P MLCAG K C+GDSGGPLVC+ + W G+VSWG GC P Y GVY ++
Sbjct: 743 PRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGV 802
Query: 285 SKWI 288
WI
Sbjct: 803 ISWI 806
>gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]
Length = 410
Score = 174 bits (440), Expect = 1e-43
Identities = 100/272 (36%), Positives = 144/272 (52%), Gaps = 17/272 (6%)
Query: 31 AALVHRQPENQGISLTG---SVACGRPSMEGKILGGVPAPERKWPWQVSVHYAGLHVCGG 87
A+ V E+ GIS G S ACG +++GG+PAP +KWPWQVS+ + +H CGG
Sbjct: 133 ASTVGEALESDGISDLGRQFSQACGH--RVSRMIGGLPAPNKKWPWQVSLQTSNIHHCGG 190
Query: 88 SILNEYWVLSAAHCFHRDKNIKIYDMYVGLVNLRVAGNHTQWYEVNRVILHPTYEMYHPI 147
S+++ WVL+AAHC R + G L G Q ++ I+ P+ + +
Sbjct: 191 SLIDRRWVLTAAHCVFRGCGWE-----GGRWLLAGIGRWDQAWKHLEDIIFPSNFDFATL 245
Query: 148 GGDVALVQLKTRIVFSESVLPVCLATPEVNLTSAN-CWATGWGLVSKQ--GETSDELQEM 204
D+AL L + +S + P CL + + CW TGWG VS+ G LQE
Sbjct: 246 TSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQET 305
Query: 205 QLPLILEPWCHLLYGHMSYIMPDMLCAGDILN----AKTVCEGDSGGPLVCEFNRSWLQI 260
+L ++ C + + + M+ G + K C+GDSGGPLVCE N +W+Q+
Sbjct: 306 ELNIMRHEKCCEMLKNKNISKSKMVTRGTVCGYNDQGKDACQGDSGGPLVCELNGTWVQV 365
Query: 261 GIVSWGRGCSNPLYPGVYASVSYFSKWICDNI 292
GIVSWG GC YPGVY VS++ KWI D++
Sbjct: 366 GIVSWGIGCGRKGYPGVYTEVSFYKKWIIDHL 397
>gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo
sapiens]
Length = 410
Score = 174 bits (440), Expect = 1e-43
Identities = 100/272 (36%), Positives = 144/272 (52%), Gaps = 17/272 (6%)
Query: 31 AALVHRQPENQGISLTG---SVACGRPSMEGKILGGVPAPERKWPWQVSVHYAGLHVCGG 87
A+ V E+ GIS G S ACG +++GG+PAP +KWPWQVS+ + +H CGG
Sbjct: 133 ASTVGEALESDGISDLGRQFSQACGH--RVSRMIGGLPAPNKKWPWQVSLQTSNIHHCGG 190
Query: 88 SILNEYWVLSAAHCFHRDKNIKIYDMYVGLVNLRVAGNHTQWYEVNRVILHPTYEMYHPI 147
S+++ WVL+AAHC R + G L G Q ++ I+ P+ + +
Sbjct: 191 SLIDRRWVLTAAHCVFRGCGWE-----GGRWLLAGIGRWDQAWKHLEDIIFPSNFDFATL 245
Query: 148 GGDVALVQLKTRIVFSESVLPVCLATPEVNLTSAN-CWATGWGLVSKQ--GETSDELQEM 204
D+AL L + +S + P CL + + CW TGWG VS+ G LQE
Sbjct: 246 TSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQET 305
Query: 205 QLPLILEPWCHLLYGHMSYIMPDMLCAGDILN----AKTVCEGDSGGPLVCEFNRSWLQI 260
+L ++ C + + + M+ G + K C+GDSGGPLVCE N +W+Q+
Sbjct: 306 ELNIMRHEKCCEMLKNKNISKSKMVTRGTVCGYNDQGKDACQGDSGGPLVCELNGTWVQV 365
Query: 261 GIVSWGRGCSNPLYPGVYASVSYFSKWICDNI 292
GIVSWG GC YPGVY VS++ KWI D++
Sbjct: 366 GIVSWGIGCGRKGYPGVYTEVSFYKKWIIDHL 397
>gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo
sapiens]
Length = 410
Score = 174 bits (440), Expect = 1e-43
Identities = 100/272 (36%), Positives = 144/272 (52%), Gaps = 17/272 (6%)
Query: 31 AALVHRQPENQGISLTG---SVACGRPSMEGKILGGVPAPERKWPWQVSVHYAGLHVCGG 87
A+ V E+ GIS G S ACG +++GG+PAP +KWPWQVS+ + +H CGG
Sbjct: 133 ASTVGEALESDGISDLGRQFSQACGH--RVSRMIGGLPAPNKKWPWQVSLQTSNIHHCGG 190
Query: 88 SILNEYWVLSAAHCFHRDKNIKIYDMYVGLVNLRVAGNHTQWYEVNRVILHPTYEMYHPI 147
S+++ WVL+AAHC R + G L G Q ++ I+ P+ + +
Sbjct: 191 SLIDRRWVLTAAHCVFRGCGWE-----GGRWLLAGIGRWDQAWKHLEDIIFPSNFDFATL 245
Query: 148 GGDVALVQLKTRIVFSESVLPVCLATPEVNLTSAN-CWATGWGLVSKQ--GETSDELQEM 204
D+AL L + +S + P CL + + CW TGWG VS+ G LQE
Sbjct: 246 TSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQET 305
Query: 205 QLPLILEPWCHLLYGHMSYIMPDMLCAGDILN----AKTVCEGDSGGPLVCEFNRSWLQI 260
+L ++ C + + + M+ G + K C+GDSGGPLVCE N +W+Q+
Sbjct: 306 ELNIMRHEKCCEMLKNKNISKSKMVTRGTVCGYNDQGKDACQGDSGGPLVCELNGTWVQV 365
Query: 261 GIVSWGRGCSNPLYPGVYASVSYFSKWICDNI 292
GIVSWG GC YPGVY VS++ KWI D++
Sbjct: 366 GIVSWGIGCGRKGYPGVYTEVSFYKKWIIDHL 397
>gi|21614531 testisin isoform 2 [Homo sapiens]
Length = 312
Score = 172 bits (437), Expect = 3e-43
Identities = 108/314 (34%), Positives = 160/314 (50%), Gaps = 22/314 (7%)
Query: 15 ALGLLLLLLVVAPPRVAALVHRQPENQGIS-LTGSVACGRPSMEGKILGGVPAPERKWPW 73
A G LLL L++A + R+PE+Q + L+G CGR + +I+GG A +WPW
Sbjct: 3 ARGALLLALLLARAGL-----RKPESQEAAPLSGP--CGRRVITSRIVGGEDAELGRWPW 55
Query: 74 QVSVHYAGLHVCGGSILNEYWVLSAAHCFHRDKN-----IKIYDMYVGLVNLRVAGNHTQ 128
Q S+ HVCG S+L+ W L+AAHCF D + + + + + +
Sbjct: 56 QGSLRLWDSHVCGVSLLSHRWALTAAHCFETDLSDPSGWMVQFGQLTSMPSFWSLQAYYT 115
Query: 129 WYEVNRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLATPEVNLTS-ANCWATG 187
Y V+ + L P Y P D+ALV+L + +++ + P+CL + +CW TG
Sbjct: 116 RYFVSNIYLSPRYLGNSPY--DIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTG 173
Query: 188 WGLVSKQGE--TSDELQEMQLPLILEPWCHLLYGHMSY---IMPDMLCAGDILNAKTVCE 242
WG + + + LQE+Q+ +I C+ L+ S+ I DM+CAG+ K C
Sbjct: 174 WGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVCAGNAQGGKDACF 233
Query: 243 GDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSKWICDNIEITPTPAQPA 302
GDSGGPL C N W QIG+VSWG GC P PGVY ++S+ +WI + +QP
Sbjct: 234 GDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWI-QKLMAQSGMSQPD 292
Query: 303 PALSPALGPTLSVL 316
P+ P L L
Sbjct: 293 PSWPLLFFPLLWAL 306
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 171 bits (432), Expect = 1e-42
Identities = 91/247 (36%), Positives = 133/247 (53%), Gaps = 6/247 (2%)
Query: 50 ACG-RPSMEGKILGGVPAPERKWPWQVSVHYAGLHVCGGSILNEYWVLSAAHCFHRDKNI 108
ACG R +I+GG + +WPWQ S+ + G H+CGGS++ W+++AAHC +
Sbjct: 206 ACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLYLP 265
Query: 109 KIYDMYVGLVNLRVAGNHTQWYEVNRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLP 168
K + + VGLV+L N + V +++ H Y+ +G D+AL++L + F+E + P
Sbjct: 266 KSWTIQVGLVSL--LDNPAPSHLVEKIVYHSKYKPKR-LGNDIALMKLAGPLTFNEMIQP 322
Query: 169 VCLATPEVNLTSAN-CWATGWGLVSK-QGETSDELQEMQLPLILEPWCHLLYGHMSYIMP 226
VCL E N CW +GWG G+ S L +PLI C+ + I P
Sbjct: 323 VCLPNSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISP 382
Query: 227 DMLCAGDILNAKTVCEGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSK 286
MLCAG + C+GDSGGPLVC+ R W +G S+G GC+ PGVY V+ F
Sbjct: 383 SMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLD 442
Query: 287 WICDNIE 293
WI + +E
Sbjct: 443 WIHEQME 449
>gi|5803197 testisin isoform 1 [Homo sapiens]
Length = 314
Score = 170 bits (431), Expect = 1e-42
Identities = 107/316 (33%), Positives = 159/316 (50%), Gaps = 24/316 (7%)
Query: 15 ALGLLLLLLVVAPPRVAALVHRQPENQGIS-LTGSVACGRPSMEGKILGGVPAPERKWPW 73
A G LLL L++A + R+PE+Q + L+G CGR + +I+GG A +WPW
Sbjct: 3 ARGALLLALLLARAGL-----RKPESQEAAPLSGP--CGRRVITSRIVGGEDAELGRWPW 55
Query: 74 QVSVHYAGLHVCGGSILNEYWVLSAAHCFHRDKNIKI-------YDMYVGLVNLRVAGNH 126
Q S+ HVCG S+L+ W L+AAHCF ++ + + + +
Sbjct: 56 QGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAY 115
Query: 127 TQWYEVNRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLATPEVNLTS-ANCWA 185
Y V+ + L P Y P D+ALV+L + +++ + P+CL + +CW
Sbjct: 116 YTRYFVSNIYLSPRYLGNSPY--DIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWV 173
Query: 186 TGWGLVSKQGE--TSDELQEMQLPLILEPWCHLLYGHMSY---IMPDMLCAGDILNAKTV 240
TGWG + + + LQE+Q+ +I C+ L+ S+ I DM+CAG+ K
Sbjct: 174 TGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVCAGNAQGGKDA 233
Query: 241 CEGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSKWICDNIEITPTPAQ 300
C GDSGGPL C N W QIG+VSWG GC P PGVY ++S+ +WI + +Q
Sbjct: 234 CFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWI-QKLMAQSGMSQ 292
Query: 301 PAPALSPALGPTLSVL 316
P P+ P L L
Sbjct: 293 PDPSWPLLFFPLLWAL 308
>gi|58218970 protease, serine, 36 [Homo sapiens]
Length = 855
Score = 169 bits (429), Expect = 2e-42
Identities = 109/303 (35%), Positives = 153/303 (50%), Gaps = 28/303 (9%)
Query: 18 LLLLLLVVAPPRVA----ALVHRQPENQGISLTGSVACGRPSMEGKILGGVPAPERKWPW 73
L L++LV++P A AL Q E + + CGRP +I+GG A WPW
Sbjct: 7 LPLVMLVISPIPGAFQDSALSPTQEEPEDLD------CGRPEPSARIVGGSNAQPGTWPW 60
Query: 74 QVSVHYAGLHVCGGSILNEYWVLSAAHCFHRDKNIKIYDMYVGLVNLR-----VAGNHTQ 128
QVS+H+ G H+CGGS++ WVLSAAHCF + ++ + L+ + + G HT+
Sbjct: 61 QVSLHHGGGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGVHSQDGPLDGAHTR 120
Query: 129 WYEVNRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLATPEVNLTSAN-CWATG 187
V +++ Y +G D+AL++L + +V PVCL CWATG
Sbjct: 121 --AVAAIVVPANYSQVE-LGADLALLRLASPASLGPAVWPVCLPRASHRFVHGTACWATG 177
Query: 188 WGLVSKQGETSDE--LQEMQLPLILEPWCHLLYGHMS------YIMPDMLCAGDILNAKT 239
WG V + LQE++L L+ E C LY I+P MLCAG +
Sbjct: 178 WGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQILPGMLCAGYPEGRRD 237
Query: 240 VCEGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSKWICDNI-EITPTP 298
C+GDSGGPLVCE W Q GI S+G GC PGV+ +V+ + WI + + P P
Sbjct: 238 TCQGDSGGPLVCEEGGRWFQAGITSFGFGCGRRNRPGVFTAVATYEAWIREQVMGSEPGP 297
Query: 299 AQP 301
A P
Sbjct: 298 AFP 300
Score = 85.9 bits (211), Expect = 4e-17
Identities = 65/245 (26%), Positives = 109/245 (44%), Gaps = 19/245 (7%)
Query: 71 WPWQVSVHYAGLHVCGGSILNEYWVLSAAHCFHR--DKNIKIYDMYVGLVNLRVAGNHTQ 128
WPW VH AG VC G +L WVL+A HC R + ++Y+G A + Q
Sbjct: 601 WPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAG---ASSLPQ 657
Query: 129 WYEVNRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLATPEVNLTSANCWATGW 188
++V+R+++ + + +AL++L +R+ S S LP+CL P A+CW GW
Sbjct: 658 GHQVSRLVISIRLPQHLGLRPPLALLELSSRVEPSPSALPICL-HPAGIPPGASCWVLGW 716
Query: 189 GLVSKQGETSDELQ-EMQLPLILEPWCHLLYGHMSYIMPDMLCAGDILNAKTVCEGDSGG 247
E D + + ++ + C LY + P LC + CE S
Sbjct: 717 ------KEPQDRVPVAAAVSILTQRICDCLY--QGILPPGTLCVLYAEGQENRCEMTSAP 768
Query: 248 PLVCEFNR-SWLQIGIVSWGRGCSNPLYPGVYASVSYFSKWICDNIEITPTPAQPAPALS 306
PL+C+ SW+ +G+ G S L+ + ++ S+ + + + P+ + P
Sbjct: 769 PLLCQMTEGSWILVGMAVQG---SRELFAAIGPEEAWISQTVGEANFLPPSGSPHWPTGG 825
Query: 307 PALGP 311
L P
Sbjct: 826 SNLCP 830
Score = 74.3 bits (181), Expect = 1e-13
Identities = 65/224 (29%), Positives = 93/224 (41%), Gaps = 25/224 (11%)
Query: 62 GGVPAPERKWPWQVSVHYAGLHVCGGSILNEYWVLSAAHCF----HRDKNIKIYDMYVGL 117
G P P WPW+ V G C G++++E WVL+ A CF D + D + L
Sbjct: 326 GKAPRPGA-WPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVL 384
Query: 118 VNLRVAGNHTQWYEVNRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLATPE-V 176
+ R V R++ H + D+AL+QL+T + S + PVCL PE
Sbjct: 385 LPSRPRAE-----RVARLVQHENASWDN--ASDLALLQLRTPVNLSAASRPVCLPHPEHY 437
Query: 177 NLTSANCWATGWGLVSKQGETS-DELQEMQLPLILEPWCHLLYGHMSYIM------PDML 229
L + C WG +GE + ++ L+ WCH LYG + P L
Sbjct: 438 FLPGSRCRLARWG----RGEPALGPGALLEAELLGGWWCHCLYGRQGAAVPLPGDPPHAL 493
Query: 230 C-AGDILNAKTVCEGDSGGPLVCEFNRSWLQIGIVSWGRGCSNP 272
C A C DS L+C+ +W GI + GC P
Sbjct: 494 CPAYQEKEEVGSCWNDSRWSLLCQEEGTWFLAGIRDFPSGCLRP 537
>gi|205360905 testis-specific serine protease 1 [Homo sapiens]
Length = 318
Score = 168 bits (425), Expect = 7e-42
Identities = 101/299 (33%), Positives = 152/299 (50%), Gaps = 34/299 (11%)
Query: 15 ALGLLLLLLVVA------PPRVAAL-----VHRQPENQGISLTGSVACGRPSMEGKILGG 63
A G LLL L++A P + AL R+P G ACG + + GG
Sbjct: 3 ARGALLLALLLARAGLGKPGELGALQAGPGAARRPGGGG----REEACGHREIHALVAGG 58
Query: 64 VPAPERKWPWQVSVHYAGLHVCGGSILNEYWVLSAAHCFHRDKNIKIYDMYVGLV----- 118
V + +WPWQ S+ H CGGS+L+ WVLSAAHCF + + + +G +
Sbjct: 59 VESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYYPSEWTVQLGELTSRPT 118
Query: 119 --NLRVAGNHTQWYEVNRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLATPEV 176
NLR ++ Y+V +I++P + + D+AL++L + + ++ + P+C+ +
Sbjct: 119 PWNLRA---YSSRYKVQDIIVNP--DALGVLRNDIALLRLASSVTYNAYIQPICIESSTF 173
Query: 177 NLTSA-NCWATGWGLVSKQGETSD---ELQEMQLPLILEPWCHLLY---GHMSYIMPDML 229
N +CW TGWGL+S G L+E Q+ ++ C+ L+ S I M
Sbjct: 174 NFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSSRSMIWDSMF 233
Query: 230 CAGDILNAKTVCEGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSKWI 288
CAG + C+GDSGGPLVC+ + W Q+GIVSWG C P PGVY ++S + WI
Sbjct: 234 CAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNISVYFHWI 292
>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
Length = 275
Score = 164 bits (415), Expect = 1e-40
Identities = 103/285 (36%), Positives = 148/285 (51%), Gaps = 33/285 (11%)
Query: 19 LLLLLVVAPPRVAALVHRQPENQGISLTGSVACGRPSMEGKILGGVPAPERKWPWQVSVH 78
+L LL++A P +A+ + P A G+ I+GG AP KWPWQVS+
Sbjct: 1 MLNLLLLALPVLASRAYAAP-----------APGQALQRVGIVGGQEAPRSKWPWQVSLR 49
Query: 79 YAG---LHVCGGSILNEYWVLSAAHCFHRDKNIKIYDMYVGLVNLRVAGNH--TQWYEVN 133
G +H CGGS+++ WVL+AAHC D + D+ V LR + Q V+
Sbjct: 50 VHGPYWMHFCGGSLIHPQWVLTAAHCVGPD----VKDLAALRVQLREQHLYYQDQLLPVS 105
Query: 134 RVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLA-TPEVNLTSANCWATGWGLVS 192
R+I+HP + IG D+AL++L+ + S V V L E CW TGWG V
Sbjct: 106 RIIVHPQFYTAQ-IGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVD 164
Query: 193 KQGETSDE--LQEMQLPLILEPWCHLLYGHMSY-------IMPDMLCAGDILNAKTVCEG 243
L+++++P++ C Y +Y + DMLCAG+ + C+G
Sbjct: 165 NDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGN--TRRDSCQG 222
Query: 244 DSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSKWI 288
DSGGPLVC+ N +WLQ G+VSWG GC+ P PG+Y V+Y+ WI
Sbjct: 223 DSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267
>gi|4505881 plasminogen [Homo sapiens]
Length = 810
Score = 162 bits (409), Expect = 5e-40
Identities = 95/252 (37%), Positives = 133/252 (52%), Gaps = 23/252 (9%)
Query: 48 SVACGRPSME-----GKILGGVPAPERKWPWQVSVHYA-GLHVCGGSILNEYWVLSAAHC 101
S CG+P +E G+++GG A WPWQVS+ G+H CGG++++ WVL+AAHC
Sbjct: 564 SFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHC 623
Query: 102 FHRDKNIKIYDMYVGL---VNLRVAGNHTQWYEVNRVILHPTYEMYHPIGGDVALVQLKT 158
+ Y + +G VNL H Q EV+R+ L PT + D+AL++L +
Sbjct: 624 LEKSPRPSSYKVILGAHQEVNLEP---HVQEIEVSRLFLEPTRK-------DIALLKLSS 673
Query: 159 RIVFSESVLPVCLATPE-VNLTSANCWATGWGLVSKQGET-SDELQEMQLPLILEPWCHL 216
V ++ V+P CL +P V C+ TGWG QG + L+E QLP+I C+
Sbjct: 674 PAVITDKVIPACLPSPNYVVADRTECFITGWG--ETQGTFGAGLLKEAQLPVIENKVCNR 731
Query: 217 LYGHMSYIMPDMLCAGDILNAKTVCEGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPG 276
+ LCAG + C+GDSGGPLVC ++ G+ SWG GC+ P PG
Sbjct: 732 YEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPG 791
Query: 277 VYASVSYFSKWI 288
VY VS F WI
Sbjct: 792 VYVRVSRFVTWI 803
>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
Length = 275
Score = 162 bits (409), Expect = 5e-40
Identities = 102/285 (35%), Positives = 147/285 (51%), Gaps = 33/285 (11%)
Query: 19 LLLLLVVAPPRVAALVHRQPENQGISLTGSVACGRPSMEGKILGGVPAPERKWPWQVSVH 78
+L LL++A P +A+ + P A G+ I+GG AP KWPWQVS+
Sbjct: 1 MLNLLLLALPVLASRAYAAP-----------APGQALQRVGIVGGQEAPRSKWPWQVSLR 49
Query: 79 YAG---LHVCGGSILNEYWVLSAAHCFHRDKNIKIYDMYVGLVNLRVAGNH--TQWYEVN 133
+H CGGS+++ WVL+AAHC D + D+ V LR + Q V+
Sbjct: 50 VRDRYWMHFCGGSLIHPQWVLTAAHCVGPD----VKDLAALRVQLREQHLYYQDQLLPVS 105
Query: 134 RVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLA-TPEVNLTSANCWATGWGLVS 192
R+I+HP + IG D+AL++L+ + S V V L E CW TGWG V
Sbjct: 106 RIIVHPQFYTAQ-IGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVD 164
Query: 193 KQGETSDE--LQEMQLPLILEPWCHLLYGHMSY-------IMPDMLCAGDILNAKTVCEG 243
L+++++P++ C Y +Y + DMLCAG+ + C+G
Sbjct: 165 NDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGN--TRRDSCQG 222
Query: 244 DSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSKWI 288
DSGGPLVC+ N +WLQ G+VSWG GC+ P PG+Y V+Y+ WI
Sbjct: 223 DSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267
>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
sapiens]
Length = 432
Score = 161 bits (407), Expect = 8e-40
Identities = 95/261 (36%), Positives = 139/261 (53%), Gaps = 14/261 (5%)
Query: 36 RQPENQGISLTGSV------ACGRPSMEGKILGGVPAPERKWPWQVSVHYAGLHVCGGSI 89
R + G L+GS+ ACG+ +++GG A WPWQVS+ Y HVCGGSI
Sbjct: 170 RMRNSSGPCLSGSLVSLHCLACGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSI 229
Query: 90 LNEYWVLSAAHCFHRDKNIKIYDMYVGLVNLRVAGNHTQWYEVNRVILHPTYEMYHPIGG 149
L+ +WVL+AAHCF + ++ + + G L G+ V ++I+ MY P
Sbjct: 230 LDPHWVLTAAHCFRKHTDVFNWKVRAGSDKL---GSFPS-LAVAKIIIIEFNPMY-PKDN 284
Query: 150 DVALVQLKTRIVFSESVLPVCLATPEVNLTSAN-CWATGWGLVSKQ-GETSDELQEMQLP 207
D+AL++L+ + FS +V P+CL + LT A W GWG + G+ SD L + +
Sbjct: 285 DIALMKLQFPLTFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQ 344
Query: 208 LILEPWCHLLYGHMSYIMPDMLCAGDILNAKTVCEGDSGGPLVCEFNRSWLQIGIVSWGR 267
+I C+ + + M+CAG C+GDSGGPL+ + ++ W +GIVSWG
Sbjct: 345 VIDSTRCNADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQ-WHVVGIVSWGY 403
Query: 268 GCSNPLYPGVYASVSYFSKWI 288
GC P PGVY VS + WI
Sbjct: 404 GCGGPSTPGVYTKVSAYLNWI 424
>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
sapiens]
Length = 437
Score = 161 bits (407), Expect = 8e-40
Identities = 95/261 (36%), Positives = 139/261 (53%), Gaps = 14/261 (5%)
Query: 36 RQPENQGISLTGSV------ACGRPSMEGKILGGVPAPERKWPWQVSVHYAGLHVCGGSI 89
R + G L+GS+ ACG+ +++GG A WPWQVS+ Y HVCGGSI
Sbjct: 175 RMRNSSGPCLSGSLVSLHCLACGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSI 234
Query: 90 LNEYWVLSAAHCFHRDKNIKIYDMYVGLVNLRVAGNHTQWYEVNRVILHPTYEMYHPIGG 149
L+ +WVL+AAHCF + ++ + + G L G+ V ++I+ MY P
Sbjct: 235 LDPHWVLTAAHCFRKHTDVFNWKVRAGSDKL---GSFPS-LAVAKIIIIEFNPMY-PKDN 289
Query: 150 DVALVQLKTRIVFSESVLPVCLATPEVNLTSAN-CWATGWGLVSKQ-GETSDELQEMQLP 207
D+AL++L+ + FS +V P+CL + LT A W GWG + G+ SD L + +
Sbjct: 290 DIALMKLQFPLTFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQ 349
Query: 208 LILEPWCHLLYGHMSYIMPDMLCAGDILNAKTVCEGDSGGPLVCEFNRSWLQIGIVSWGR 267
+I C+ + + M+CAG C+GDSGGPL+ + ++ W +GIVSWG
Sbjct: 350 VIDSTRCNADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQ-WHVVGIVSWGY 408
Query: 268 GCSNPLYPGVYASVSYFSKWI 288
GC P PGVY VS + WI
Sbjct: 409 GCGGPSTPGVYTKVSAYLNWI 429
>gi|33695155 hepsin [Homo sapiens]
Length = 417
Score = 160 bits (404), Expect = 2e-39
Identities = 96/255 (37%), Positives = 133/255 (52%), Gaps = 14/255 (5%)
Query: 51 CGRPSME-GKILGGVPAPERKWPWQVSVHYAGLHVCGGSILNEYWVLSAAHCF-HRDKNI 108
CGR + +I+GG +WPWQVS+ Y G H+CGGS+L+ WVL+AAHCF R++ +
Sbjct: 153 CGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVL 212
Query: 109 KIYDMYVGLVNLRVAGNHTQWYEVNRVILHPTYEMY-----HPIGGDVALVQLKTRIVFS 163
+ ++ G V A H V V+ H Y + D+ALV L + + +
Sbjct: 213 SRWRVFAGAV--AQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLT 270
Query: 164 ESVLPVCL-ATPEVNLTSANCWATGWGLVSKQGETSDELQEMQLPLILEPWCHLLYGHMS 222
E + PVCL A + + C TGWG G+ + LQE ++P+I C+ + +
Sbjct: 271 EYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGN 330
Query: 223 YIMPDMLCAGDILNAKTVCEGDSGGPLVCEFNRS----WLQIGIVSWGRGCSNPLYPGVY 278
I P M CAG C+GDSGGP VCE + S W GIVSWG GC+ PGVY
Sbjct: 331 QIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVY 390
Query: 279 ASVSYFSKWICDNIE 293
VS F +WI I+
Sbjct: 391 TKVSDFREWIFQAIK 405
>gi|4504481 hepsin [Homo sapiens]
Length = 417
Score = 160 bits (404), Expect = 2e-39
Identities = 96/255 (37%), Positives = 133/255 (52%), Gaps = 14/255 (5%)
Query: 51 CGRPSME-GKILGGVPAPERKWPWQVSVHYAGLHVCGGSILNEYWVLSAAHCF-HRDKNI 108
CGR + +I+GG +WPWQVS+ Y G H+CGGS+L+ WVL+AAHCF R++ +
Sbjct: 153 CGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVL 212
Query: 109 KIYDMYVGLVNLRVAGNHTQWYEVNRVILHPTYEMY-----HPIGGDVALVQLKTRIVFS 163
+ ++ G V A H V V+ H Y + D+ALV L + + +
Sbjct: 213 SRWRVFAGAV--AQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLT 270
Query: 164 ESVLPVCL-ATPEVNLTSANCWATGWGLVSKQGETSDELQEMQLPLILEPWCHLLYGHMS 222
E + PVCL A + + C TGWG G+ + LQE ++P+I C+ + +
Sbjct: 271 EYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGN 330
Query: 223 YIMPDMLCAGDILNAKTVCEGDSGGPLVCEFNRS----WLQIGIVSWGRGCSNPLYPGVY 278
I P M CAG C+GDSGGP VCE + S W GIVSWG GC+ PGVY
Sbjct: 331 QIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVY 390
Query: 279 ASVSYFSKWICDNIE 293
VS F +WI I+
Sbjct: 391 TKVSDFREWIFQAIK 405
>gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]
Length = 2040
Score = 158 bits (400), Expect = 5e-39
Identities = 96/253 (37%), Positives = 132/253 (52%), Gaps = 30/253 (11%)
Query: 46 TGSVACGRPSME-----GKILGGVPAPERKWPWQVSVHYA-GLHVCGGSILNEYWVLSAA 99
+ S CG+P +E G I+GG A WPWQVS+ G H CGG++++ WVL+AA
Sbjct: 1801 SSSFDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLISPEWVLTAA 1860
Query: 100 HCFHRDKNIKIYDMYVGL---VNLRVAGNHTQWYEVNRVILHPTYEMYHPIGGDVALVQL 156
HC + Y + +G VNL +H Q EV+R+ L PT D+AL++L
Sbjct: 1861 HCLKKSSRPSSYKVILGAHQEVNLE---SHVQEIEVSRLFLEPTQ-------ADIALLKL 1910
Query: 157 KTRIVFSESVLPVCLATPEVNLTS-ANCWATGWGLVSKQGETSDELQEMQLPLILEPWCH 215
V ++ V+P CL +P+ +T+ C+ TGWG T L+E QL +I C+
Sbjct: 1911 SRPAVITDKVMPACLPSPDYMVTARTECYITGWGETQGTFGTG-LLKEAQLLVIENEVCN 1969
Query: 216 LLYGHMSYIMPDMLCAGDILNAKTVCEGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYP 275
H YI CA + C+GDSGGPLVC ++ G+ SWG GC+ P P
Sbjct: 1970 ----HYKYI-----CAEHLARGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKP 2020
Query: 276 GVYASVSYFSKWI 288
GVYA VS F WI
Sbjct: 2021 GVYARVSRFVTWI 2033
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.454
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,338,560
Number of Sequences: 37866
Number of extensions: 706667
Number of successful extensions: 2654
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 168
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2021
Number of HSP's gapped (non-prelim): 204
length of query: 326
length of database: 18,247,518
effective HSP length: 103
effective length of query: 223
effective length of database: 14,347,320
effective search space: 3199452360
effective search space used: 3199452360
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.