Guide to the Human Genome
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Search of human proteins with 33667038

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33667038 syntaxin 11 [Homo sapiens]
         (287 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33667038 syntaxin 11 [Homo sapiens]                                571   e-163
gi|49258196 syntaxin 19 [Homo sapiens]                                217   1e-56
gi|16418379 syntaxin 1B [Homo sapiens]                                174   6e-44
gi|37577287 syntaxin 2 isoform 1 [Homo sapiens]                       169   3e-42
gi|37577162 syntaxin 2 isoform 2 [Homo sapiens]                       169   3e-42
gi|4759182 syntaxin 1A (brain) [Homo sapiens]                         154   7e-38
gi|4759184 syntaxin 3 [Homo sapiens]                                  144   9e-35
gi|20149560 syntaxin 4 [Homo sapiens]                                 118   5e-27
gi|28933465 syntaxin 12 [Homo sapiens]                                 54   2e-07
gi|170932494 syntaxin 7 [Homo sapiens]                                 50   2e-06
gi|47778943 syntaxin 16 isoform a [Homo sapiens]                       48   9e-06
gi|198041692 syntaxin 16 isoform d [Homo sapiens]                      48   9e-06
gi|198041688 syntaxin 16 isoform c [Homo sapiens]                      48   9e-06
gi|34447229 syntaxin 16 isoform b [Homo sapiens]                       48   9e-06
gi|223972648 t-SNARE domain containing 1 [Homo sapiens]                39   0.007
gi|55770834 centromere protein F [Homo sapiens]                        39   0.007
gi|4505489 ornithine decarboxylase 1 [Homo sapiens]                    37   0.020
gi|13540600 nudE nuclear distribution gene E homolog (A. nidulan...    37   0.026
gi|71284108 nudE nuclear distribution gene E homolog (A. nidulan...    37   0.026
gi|118498362 kinectin 1 isoform b [Homo sapiens]                       36   0.034
gi|118498356 kinectin 1 isoform a [Homo sapiens]                       36   0.034
gi|33620775 kinectin 1 isoform a [Homo sapiens]                        36   0.034
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         35   0.099
gi|61966741 TMF regulated nuclear protein [Homo sapiens]               35   0.099
gi|95089461 discs large homolog 5 [Homo sapiens]                       34   0.13 
gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom...    34   0.17 
gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom...    34   0.17 
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     34   0.17 
gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo sa...    33   0.29 
gi|75750468 spectrin domain with coiled-coils 1 NSP5a3a [Homo sa...    33   0.29 

>gi|33667038 syntaxin 11 [Homo sapiens]
          Length = 287

 Score =  571 bits (1471), Expect = e-163
 Identities = 287/287 (100%), Positives = 287/287 (100%)

Query: 1   MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA 60
           MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA
Sbjct: 1   MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA 60

Query: 61  DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP 120
           DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP
Sbjct: 61  DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP 120

Query: 121 HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM 180
           HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM
Sbjct: 121 HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM 180

Query: 181 FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD 240
           FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD
Sbjct: 181 FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD 240

Query: 241 TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK 287
           TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK
Sbjct: 241 TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK 287


>gi|49258196 syntaxin 19 [Homo sapiens]
          Length = 294

 Score =  217 bits (552), Expect = 1e-56
 Identities = 108/291 (37%), Positives = 184/291 (63%), Gaps = 7/291 (2%)

Query: 1   MKDRLAEL------LDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDE 54
           MKDRL EL      ++LS+       + +++     + +++E + + E    +I+ +Q+ 
Sbjct: 1   MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQES 60

Query: 55  NQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAA 114
              L  +V++ G+Q    + SMRR S +KR++ +I K IK + E I+  L  + +  + +
Sbjct: 61  INNLADNVQKFGQQQKSLVASMRRFSLLKRES-TITKEIKIQAEYINRSLNDLVKEVKKS 119

Query: 115 EAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSG 174
           E ++GP S V RI ++Q+ A+   FQ+ M  YN     +++ CK  I RQLE+ GKE+S 
Sbjct: 120 EVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSE 179

Query: 175 DQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVL 234
           + + DM  QGKW+VF+E+LL ++   +A L+EIE RH+EL+ LE++I+D+ +LF+Q+++L
Sbjct: 180 EDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLL 239

Query: 235 VEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPC 285
           VE+Q +++N IE+ V  T +Y    K +   AV+Y+++NPCR LCC+CCPC
Sbjct: 240 VEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRNPCRVLCCWCCPC 290


>gi|16418379 syntaxin 1B [Homo sapiens]
          Length = 288

 Score =  174 bits (442), Expect = 6e-44
 Identities = 98/287 (34%), Positives = 163/287 (56%), Gaps = 14/287 (4%)

Query: 1   MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA 60
           MKDR  EL        +   D DDE +  H D     DH ++  +  + +I+   + L  
Sbjct: 1   MKDRTQEL--------RSAKDSDDEEEVVHVD----RDHFMDEFFEQVEEIRGCIEKLSE 48

Query: 61  DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP 120
           DV+++ KQ++  L +       K++   +   IK     +  KL+A+++  E  E  +  
Sbjct: 49  DVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRS 108

Query: 121 HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM 180
            SA  RI + Q++ L+  F   M +YN  + K RD CK RIQRQLEI G+  + +++EDM
Sbjct: 109 -SADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDM 167

Query: 181 FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD 240
            E GK  +F++++  D +  + ALNEIE+RH E+++LE+ IR++H++F+ MA+LVE Q +
Sbjct: 168 LESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGE 227

Query: 241 TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEK-NPCRTLCCFCCPCL 286
            ++ IE NV+ +VDY  +A +  +KAV+Y+ K    + +   CC  L
Sbjct: 228 MIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVVL 274


>gi|37577287 syntaxin 2 isoform 1 [Homo sapiens]
          Length = 287

 Score =  169 bits (428), Expect = 3e-42
 Identities = 94/283 (33%), Positives = 159/283 (56%), Gaps = 13/283 (4%)

Query: 1   MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA 60
           M+DRL +L    K       DGD         +V E DH ++  +  + +I++    +  
Sbjct: 1   MRDRLPDLTACRKN-----DDGDTV-------VVVEKDHFMDDFFHQVEEIRNSIDKITQ 48

Query: 61  DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP 120
            V+ + K ++  L++      IK +   + K IK     I  KL+A+++  +  E+ +  
Sbjct: 49  YVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRT 108

Query: 121 HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM 180
            S   RI R Q++ L+  F  AM +YN+A+   R+  K RIQRQLEI G+  + D++E+M
Sbjct: 109 -SVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEM 167

Query: 181 FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD 240
            E GK  +F+ ++++D +  R ALNEIESRH+++++LE+ IR++HE+F+ MA+ VE Q +
Sbjct: 168 LESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGE 227

Query: 241 TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCC 283
            +N IE NV    DY   AK + +KA++Y+ K   + +    C
Sbjct: 228 MINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKLMFIIIC 270


>gi|37577162 syntaxin 2 isoform 2 [Homo sapiens]
          Length = 288

 Score =  169 bits (427), Expect = 3e-42
 Identities = 93/272 (34%), Positives = 156/272 (57%), Gaps = 13/272 (4%)

Query: 1   MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA 60
           M+DRL +L    K       DGD         +V E DH ++  +  + +I++    +  
Sbjct: 1   MRDRLPDLTACRKN-----DDGDTV-------VVVEKDHFMDDFFHQVEEIRNSIDKITQ 48

Query: 61  DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP 120
            V+ + K ++  L++      IK +   + K IK     I  KL+A+++  +  E+ +  
Sbjct: 49  YVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRT 108

Query: 121 HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM 180
            S   RI R Q++ L+  F  AM +YN+A+   R+  K RIQRQLEI G+  + D++E+M
Sbjct: 109 -SVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEM 167

Query: 181 FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD 240
            E GK  +F+ ++++D +  R ALNEIESRH+++++LE+ IR++HE+F+ MA+ VE Q +
Sbjct: 168 LESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGE 227

Query: 241 TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEK 272
            +N IE NV    DY   AK + +KA++Y+ K
Sbjct: 228 MINNIERNVMNATDYVEHAKEETKKAIKYQSK 259


>gi|4759182 syntaxin 1A (brain) [Homo sapiens]
          Length = 288

 Score =  154 bits (390), Expect = 7e-38
 Identities = 87/287 (30%), Positives = 155/287 (54%), Gaps = 13/287 (4%)

Query: 1   MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA 60
           MKDR  EL        +   D DD+ D     +  + D  ++  +  + +I+     +  
Sbjct: 1   MKDRTQEL--------RTAKDSDDDDDVA---VTVDRDRFMDEFFEQVEEIRGFIDKIAE 49

Query: 61  DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP 120
           +V+ + ++++  L S       K +   +   IK     +  KL+++++  E  E  +  
Sbjct: 50  NVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRS 109

Query: 121 HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM 180
            SA  RI + Q++ L+  F   M +YN  +   R+ CK RIQRQLEI G+  + +++EDM
Sbjct: 110 -SADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDM 168

Query: 181 FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD 240
            E G   +F+  ++ D   ++ AL+EIE+RH E+++LE+ IR++H++F+ MA+LVE Q +
Sbjct: 169 LESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGE 228

Query: 241 TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEK-NPCRTLCCFCCPCL 286
            ++ IE NV+  VDY  +A +  +KAV+Y+ K    + +   CC  L
Sbjct: 229 MIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVIL 275


>gi|4759184 syntaxin 3 [Homo sapiens]
          Length = 289

 Score =  144 bits (363), Expect = 9e-35
 Identities = 89/272 (32%), Positives = 158/272 (58%), Gaps = 13/272 (4%)

Query: 1   MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA 60
           MKDRL +L   +KQ  Q     DD+ D+   +I  +    ++  + +I + +     +  
Sbjct: 1   MKDRLEQLK--AKQLTQ-----DDDTDAV--EIAIDNTAFMDEFFSEIEETRLNIDKISE 51

Query: 61  DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP 120
            V+   K  +  L++       K D   +   IK R   +  KL++M++  E  E +   
Sbjct: 52  HVEEAKKLYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEVRS-- 109

Query: 121 HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM 180
            SA  RI ++Q++ L+  F   M  YN+A++  R+  K RIQRQLEI GK+ + +++E+M
Sbjct: 110 -SADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEM 168

Query: 181 FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD 240
            E G   +F+  ++ D + ++ AL+EIE RH++++RLES I+++H++F+ +A+LVE Q +
Sbjct: 169 LESGNPAIFTSGII-DSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGE 227

Query: 241 TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEK 272
            L+ IELNV  TVD+  +A+ + +KAV+Y+ +
Sbjct: 228 MLDNIELNVMHTVDHVEKARDETKKAVKYQSQ 259


>gi|20149560 syntaxin 4 [Homo sapiens]
          Length = 297

 Score =  118 bits (296), Expect = 5e-27
 Identities = 81/278 (29%), Positives = 139/278 (50%), Gaps = 16/278 (5%)

Query: 1   MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHIL-----ESLYRDIRDIQDEN 55
           M+DR  EL        +Q  D  DE D     +V            E  +  +R I+   
Sbjct: 1   MRDRTHEL--------RQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTI 52

Query: 56  QLLVADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAE 115
             L   V+ L KQ    L +     S+K++  ++   IK  G  I  +L+A++   E A+
Sbjct: 53  VKLGNKVQELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEAD 112

Query: 116 AQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKE-VSG 174
             +  +S   R+ + Q+  L+  F   ++  N  + + R+    RI+RQL+I     VS 
Sbjct: 113 ENY--NSVNTRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSD 170

Query: 175 DQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVL 234
           +++E M + G+ +VF  N+L D +  R ALNEI +RH E+ +LE  IR++H++F  +A  
Sbjct: 171 EELEQMLDSGQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATE 230

Query: 235 VEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEK 272
           VE Q + +N IE N+  + DY  + +  V+ A++ ++K
Sbjct: 231 VEMQGEMINRIEKNILSSADYVERGQEHVKTALENQKK 268


>gi|28933465 syntaxin 12 [Homo sapiens]
          Length = 276

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 49/235 (20%), Positives = 108/235 (45%), Gaps = 15/235 (6%)

Query: 48  IRDIQDENQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAM 107
           +RD     Q    +++R+ +  A+    M +L + K+D++ + + ++   ++ H   +  
Sbjct: 19  LRDFSSIIQTCSGNIQRISQATAQIKNLMSQLGT-KQDSSKLQENLQ---QLQHSTNQLA 74

Query: 108 KE----LSEAAEAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQR 163
           KE    L E         ++  R  R Q   L   F  A++++   + +  +  K  I R
Sbjct: 75  KETNELLKELGSLPLPLSTSEQRQQRLQKERLMNDFSAALNNFQAVQRRVSEKEKESIAR 134

Query: 164 QLEIMGKEVSGDQIEDMFEQGKWDVFSENLLADVKGARAALNE-----IESRHRELLRLE 218
                G  +S ++ +   +   +D   E      +    A+ E     I+ R   + +LE
Sbjct: 135 ARA--GSRLSAEERQREEQLVSFDSHEEWNQMQSQEDEVAITEQDLELIKERETAIRQLE 192

Query: 219 SRIRDVHELFLQMAVLVEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKN 273
           + I DV+++F  +A+++  Q D ++ IE NV+ +  +  +A  Q+++A  Y++K+
Sbjct: 193 ADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATEQLQRAAYYQKKS 247


>gi|170932494 syntaxin 7 [Homo sapiens]
          Length = 261

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 1/76 (1%)

Query: 204 LNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQADTLNVIELNVQKTVDYTGQAKAQV 263
           L  I  R   + +LE+ I D++E+F  + +++ +Q D ++ IE NV+    +  QA  Q+
Sbjct: 165 LRLIHERESSIRQLEADIMDINEIFKDLGMMIHEQGDVIDSIEANVENAEVHVQQANQQL 224

Query: 264 RKAVQYEEKNPCRTLC 279
            +A  Y+ K+  +TLC
Sbjct: 225 SRAADYQRKSR-KTLC 239


>gi|47778943 syntaxin 16 isoform a [Homo sapiens]
          Length = 325

 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 54/225 (24%), Positives = 102/225 (45%), Gaps = 25/225 (11%)

Query: 61  DVKRLGKQNARFLTSMR-------RLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEA 113
           DV R+ KQ  + L S+         L     + ++I    +   ++ H   RA++ L   
Sbjct: 88  DVGRI-KQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSR 146

Query: 114 AEA---QHGP--HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIM 168
           A A   Q G    + VA +++A    L+ +F+ A   Y    +K+  N + R Q   +  
Sbjct: 147 ARACSEQEGRLLGNVVASLAQA-LQELSTSFRHAQSGY----LKRMKNREERSQHFFDTS 201

Query: 169 GKEVSGDQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELF 228
              +       ++ +G    F+E+ L  V+        +E R RE+ ++   I D++E+F
Sbjct: 202 VPLMDDGDDNTLYHRG----FTEDQLVLVEQNTLM---VEEREREIRQIVQSISDLNEIF 254

Query: 229 LQMAVLVEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKN 273
             +  ++ +Q   L+ I+ NV+++   T     Q+ KA QY++KN
Sbjct: 255 RDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKN 299


>gi|198041692 syntaxin 16 isoform d [Homo sapiens]
          Length = 308

 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 54/225 (24%), Positives = 102/225 (45%), Gaps = 25/225 (11%)

Query: 61  DVKRLGKQNARFLTSMR-------RLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEA 113
           DV R+ KQ  + L S+         L     + ++I    +   ++ H   RA++ L   
Sbjct: 71  DVGRI-KQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSR 129

Query: 114 AEA---QHGP--HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIM 168
           A A   Q G    + VA +++A    L+ +F+ A   Y    +K+  N + R Q   +  
Sbjct: 130 ARACSEQEGRLLGNVVASLAQA-LQELSTSFRHAQSGY----LKRMKNREERSQHFFDTS 184

Query: 169 GKEVSGDQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELF 228
              +       ++ +G    F+E+ L  V+        +E R RE+ ++   I D++E+F
Sbjct: 185 VPLMDDGDDNTLYHRG----FTEDQLVLVEQNTLM---VEEREREIRQIVQSISDLNEIF 237

Query: 229 LQMAVLVEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKN 273
             +  ++ +Q   L+ I+ NV+++   T     Q+ KA QY++KN
Sbjct: 238 RDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKN 282


>gi|198041688 syntaxin 16 isoform c [Homo sapiens]
          Length = 321

 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 54/225 (24%), Positives = 102/225 (45%), Gaps = 25/225 (11%)

Query: 61  DVKRLGKQNARFLTSMR-------RLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEA 113
           DV R+ KQ  + L S+         L     + ++I    +   ++ H   RA++ L   
Sbjct: 84  DVGRI-KQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSR 142

Query: 114 AEA---QHGP--HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIM 168
           A A   Q G    + VA +++A    L+ +F+ A   Y    +K+  N + R Q   +  
Sbjct: 143 ARACSEQEGRLLGNVVASLAQA-LQELSTSFRHAQSGY----LKRMKNREERSQHFFDTS 197

Query: 169 GKEVSGDQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELF 228
              +       ++ +G    F+E+ L  V+        +E R RE+ ++   I D++E+F
Sbjct: 198 VPLMDDGDDNTLYHRG----FTEDQLVLVEQNTLM---VEEREREIRQIVQSISDLNEIF 250

Query: 229 LQMAVLVEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKN 273
             +  ++ +Q   L+ I+ NV+++   T     Q+ KA QY++KN
Sbjct: 251 RDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKN 295


>gi|34447229 syntaxin 16 isoform b [Homo sapiens]
          Length = 304

 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 54/225 (24%), Positives = 102/225 (45%), Gaps = 25/225 (11%)

Query: 61  DVKRLGKQNARFLTSMR-------RLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEA 113
           DV R+ KQ  + L S+         L     + ++I    +   ++ H   RA++ L   
Sbjct: 67  DVGRI-KQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSR 125

Query: 114 AEA---QHGP--HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIM 168
           A A   Q G    + VA +++A    L+ +F+ A   Y    +K+  N + R Q   +  
Sbjct: 126 ARACSEQEGRLLGNVVASLAQA-LQELSTSFRHAQSGY----LKRMKNREERSQHFFDTS 180

Query: 169 GKEVSGDQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELF 228
              +       ++ +G    F+E+ L  V+        +E R RE+ ++   I D++E+F
Sbjct: 181 VPLMDDGDDNTLYHRG----FTEDQLVLVEQNTLM---VEEREREIRQIVQSISDLNEIF 233

Query: 229 LQMAVLVEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKN 273
             +  ++ +Q   L+ I+ NV+++   T     Q+ KA QY++KN
Sbjct: 234 RDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKN 278


>gi|223972648 t-SNARE domain containing 1 [Homo sapiens]
          Length = 513

 Score = 38.5 bits (88), Expect = 0.007
 Identities = 45/242 (18%), Positives = 103/242 (42%), Gaps = 15/242 (6%)

Query: 50  DIQDENQLLVADVKRLGKQNA---RFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRA 106
           ++Q+  Q + A+V R+        R L S+   S  +   +S+  A +   + I     +
Sbjct: 256 NLQELFQEMSANVFRINSSVTSLERSLQSLGTPSDTQELRDSLHTAQQETNKTIAASASS 315

Query: 107 MKELSEAAEAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRI----- 161
           +K+++E   +   P   + +  R Q + L      A+  Y   + K  +  +  +     
Sbjct: 316 VKQMAELLRSSC-PQERLQQ-ERPQLDRLKTQLSDAIQCYGVVQKKIAEKSRALLPMAQR 373

Query: 162 --QRQLEIMGKEVSGDQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLES 219
             ++  +    E++ D+         W    + LL D+      L  I  R   +L++ES
Sbjct: 374 GSKQSPQAPFAELADDEKVFNGSDNMWQGQEQALLPDI--TEEDLEAIRLREEAILQMES 431

Query: 220 RIRDVHELFLQMAVLVEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLC 279
            + DV+++   +A +V +Q + ++ IE +++    +   A+  +  A +++ +   +  C
Sbjct: 432 NLLDVNQIIKDLASMVSEQGEAVDSIEASLEAASSHAEAARQLLAGASRHQLQRH-KIKC 490

Query: 280 CF 281
           CF
Sbjct: 491 CF 492


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 38.5 bits (88), Expect = 0.007
 Identities = 49/234 (20%), Positives = 108/234 (46%), Gaps = 18/234 (7%)

Query: 25   EFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVADVKRLGKQNARFLTSMRRLSSIKR 84
            E  S H+++V ET   LE+  ++++ + D+ +   A+++ L K N     S++ L  +  
Sbjct: 890  EDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLS- 948

Query: 85   DTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGPHSAV-ARISRAQYNALTLTFQRAM 143
            +T S+ K  K    +I    R ++EL++    ++G    + A +++ + N +    Q++ 
Sbjct: 949  ETLSLEK--KEMSSIISLNKREIEELTQ----ENGTLKEINASLNQEKMNLI----QKSE 998

Query: 144  HDYNQAEMKQRDNCKIRIQRQLE----IMGKEVSGDQIEDMFEQGKWDVFSENLLADVKG 199
               N  + +++   ++  Q + E    +   E +G+  ED+ ++ K      + L  +  
Sbjct: 999  SFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLN 1058

Query: 200  ARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQADTLNVIELNVQKTV 253
               +L   E+R  EL +L+      H+ FL      E++   L +    VQ+ +
Sbjct: 1059 ECTSL--CENRKNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQAL 1110


>gi|4505489 ornithine decarboxylase 1 [Homo sapiens]
          Length = 461

 Score = 37.0 bits (84), Expect = 0.020
 Identities = 24/96 (25%), Positives = 49/96 (51%), Gaps = 4/96 (4%)

Query: 22  GDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVADVKRLGKQNARFLTSMRRLS- 80
           G++EFD    D  F    IL+    ++    D++   VAD+  + K++ R+L ++ R++ 
Sbjct: 5   GNEEFDCHFLDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTP 64

Query: 81  --SIK-RDTNSIAKAIKARGEVIHCKLRAMKELSEA 113
             ++K  D+ +I K + A G    C  +   +L ++
Sbjct: 65  FYAVKCNDSKAIVKTLAATGTGFDCASKTEIQLVQS 100


>gi|13540600 nudE nuclear distribution gene E homolog (A.
           nidulans)-like 1 isoform B [Homo sapiens]
          Length = 345

 Score = 36.6 bits (83), Expect = 0.026
 Identities = 39/171 (22%), Positives = 76/171 (44%), Gaps = 21/171 (12%)

Query: 1   MKDRLAELLDLSKQYDQQFPDGDDE---FDSPHEDIVFETDHILESLYRDIRDIQDENQL 57
           +K+  A   +LS +Y Q F +  DE   F     ++  E +  L    +  RD+Q +NQ 
Sbjct: 12  LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71

Query: 58  LVADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQ 117
           L  +V+ L ++         +  S+  D  S  +AIK   E +H  +R +++ ++  E  
Sbjct: 72  LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIK---EQLHKYVRELEQANDDLE-- 126

Query: 118 HGPHSAVARISRAQYNALTLTFQR-----AMHDYNQAEMKQRDNCKIRIQR 163
                   R  RA   +L    QR       + + ++E+ ++++  + +QR
Sbjct: 127 --------RAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQR 169


>gi|71284108 nudE nuclear distribution gene E homolog (A.
           nidulans)-like 1 isoform A [Homo sapiens]
          Length = 328

 Score = 36.6 bits (83), Expect = 0.026
 Identities = 39/171 (22%), Positives = 76/171 (44%), Gaps = 21/171 (12%)

Query: 1   MKDRLAELLDLSKQYDQQFPDGDDE---FDSPHEDIVFETDHILESLYRDIRDIQDENQL 57
           +K+  A   +LS +Y Q F +  DE   F     ++  E +  L    +  RD+Q +NQ 
Sbjct: 12  LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71

Query: 58  LVADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQ 117
           L  +V+ L ++         +  S+  D  S  +AIK   E +H  +R +++ ++  E  
Sbjct: 72  LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIK---EQLHKYVRELEQANDDLE-- 126

Query: 118 HGPHSAVARISRAQYNALTLTFQR-----AMHDYNQAEMKQRDNCKIRIQR 163
                   R  RA   +L    QR       + + ++E+ ++++  + +QR
Sbjct: 127 --------RAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQR 169


>gi|118498362 kinectin 1 isoform b [Homo sapiens]
          Length = 1306

 Score = 36.2 bits (82), Expect = 0.034
 Identities = 41/221 (18%), Positives = 86/221 (38%), Gaps = 14/221 (6%)

Query: 31   EDIVFETDHILESLYRDIRDIQDENQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNSIA 90
            E ++ E +  L S  + ++D+QDEN+L  + +++L +QN +  +S             + 
Sbjct: 923  EAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSF-------PPHEELL 975

Query: 91   KAIKARGEVIHCKLRAMKELSEAAEAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAE 150
            K I  R + I      +  L +A E Q   ++ +   +     AL  T +      N+  
Sbjct: 976  KVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTS 1035

Query: 151  MKQRDNCKIRIQRQLEIMGKEVSGDQIEDMFEQGKWDVFSENLLADVKGARAALNEIESR 210
             +++   +       E++ K      +      G+W    E    +     +   E++  
Sbjct: 1036 KERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKV- 1094

Query: 211  HRELLRLESRIRDVHELFLQMAVLVEKQADTLNVIELNVQK 251
                  LE ++++  E+   + +  EK    L   E  +QK
Sbjct: 1095 ------LEHKLKEADEMHTLLQLECEKYKSVLAETEGILQK 1129



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 54/255 (21%), Positives = 117/255 (45%), Gaps = 31/255 (12%)

Query: 27  DSPHEDIVFETDHILESLYRDIRDIQD--ENQLLVADVKR-----LGKQNARFLTSMRRL 79
           + P++D+V + +  ++     ++ +++  E  L+    K      +  +N+     ++ L
Sbjct: 723 EQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDL 782

Query: 80  SSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGPHSAVARISRAQYNALTLTF 139
            + + D  S A  ++   +VIH K   +K + E  EA+      +   ++ +   L++T 
Sbjct: 783 KAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAE-----LLKVANKEKTVQLSIT- 836

Query: 140 QRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDMFEQGKW--DVFSEN--LLA 195
                    +++++  N     + Q+  M K V  ++ +D+   GKW  D+  EN  L A
Sbjct: 837 ---------SKVQELQNLLKGKEEQMNTM-KAVLEEKEKDLANTGKWLQDLQEENESLKA 886

Query: 196 DVKG-ARAALNEIESRHR-ELLRLESRIRDVHELFLQMAVLVEKQADTLNVIELNVQKTV 253
            V+  A+  L E  S  + E L +  + ++ +EL    A+L E+++D  +  +L +Q   
Sbjct: 887 HVQEVAQHNLKEASSASQFEELEIVLKEKE-NELKRLEAMLKERESDLSSKTQL-LQDVQ 944

Query: 254 DYTGQAKAQVRKAVQ 268
           D     K+Q+ +  Q
Sbjct: 945 DENKLFKSQIEQLKQ 959



 Score = 28.5 bits (62), Expect = 7.1
 Identities = 36/187 (19%), Positives = 82/187 (43%), Gaps = 19/187 (10%)

Query: 2    KDRLAELLDLSKQYD-QQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA 60
            K++  +L   SK  + Q    G +E  +  + ++ E +  L +  + ++D+Q+EN+ L A
Sbjct: 827  KEKTVQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKA 886

Query: 61   DVKRLGKQNARFLTS---MRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQ 117
             V+ + + N +  +S      L  + ++  +  K ++A  +     L +  +L +  + +
Sbjct: 887  HVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDE 946

Query: 118  HGPHSAVARISRAQYNALTLTFQRAMHDYNQAEM--KQRDNCKIRIQRQLEIMGKEVSGD 175
            +       ++ ++Q        Q    +Y QA       +  K+  +R+ EI G     D
Sbjct: 947  N-------KLFKSQIE------QLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELD 993

Query: 176  QIEDMFE 182
             ++D  E
Sbjct: 994  SLKDAVE 1000


>gi|118498356 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 36.2 bits (82), Expect = 0.034
 Identities = 41/221 (18%), Positives = 86/221 (38%), Gaps = 14/221 (6%)

Query: 31   EDIVFETDHILESLYRDIRDIQDENQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNSIA 90
            E ++ E +  L S  + ++D+QDEN+L  + +++L +QN +  +S             + 
Sbjct: 946  EAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSF-------PPHEELL 998

Query: 91   KAIKARGEVIHCKLRAMKELSEAAEAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAE 150
            K I  R + I      +  L +A E Q   ++ +   +     AL  T +      N+  
Sbjct: 999  KVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTS 1058

Query: 151  MKQRDNCKIRIQRQLEIMGKEVSGDQIEDMFEQGKWDVFSENLLADVKGARAALNEIESR 210
             +++   +       E++ K      +      G+W    E    +     +   E++  
Sbjct: 1059 KERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKV- 1117

Query: 211  HRELLRLESRIRDVHELFLQMAVLVEKQADTLNVIELNVQK 251
                  LE ++++  E+   + +  EK    L   E  +QK
Sbjct: 1118 ------LEHKLKEADEMHTLLQLECEKYKSVLAETEGILQK 1152



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 55/263 (20%), Positives = 118/263 (44%), Gaps = 24/263 (9%)

Query: 27  DSPHEDIVFETDHILESLYRDIRDIQD--ENQLLVADVKR-----LGKQNARFLTSMRRL 79
           + P++D+V + +  ++     ++ +++  E  L+    K      +  +N+     ++ L
Sbjct: 723 EQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDL 782

Query: 80  SSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQ---HGPHSAVARISRAQYNAL- 135
            + + D  S A  ++   +VIH K   +K + E  EA+           +  + +  AL 
Sbjct: 783 KAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALK 842

Query: 136 ----TLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDMFEQGKW--DVF 189
                +  ++A      +++++  N     + Q+  M K V  ++ +D+   GKW  D+ 
Sbjct: 843 EEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTM-KAVLEEKEKDLANTGKWLQDLQ 901

Query: 190 SEN--LLADVKG-ARAALNEIESRHR-ELLRLESRIRDVHELFLQMAVLVEKQADTLNVI 245
            EN  L A V+  A+  L E  S  + E L +  + ++ +EL    A+L E+++D  +  
Sbjct: 902 EENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKE-NELKRLEAMLKERESDLSSKT 960

Query: 246 ELNVQKTVDYTGQAKAQVRKAVQ 268
           +L +Q   D     K+Q+ +  Q
Sbjct: 961 QL-LQDVQDENKLFKSQIEQLKQ 982


>gi|33620775 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 36.2 bits (82), Expect = 0.034
 Identities = 41/221 (18%), Positives = 86/221 (38%), Gaps = 14/221 (6%)

Query: 31   EDIVFETDHILESLYRDIRDIQDENQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNSIA 90
            E ++ E +  L S  + ++D+QDEN+L  + +++L +QN +  +S             + 
Sbjct: 946  EAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSF-------PPHEELL 998

Query: 91   KAIKARGEVIHCKLRAMKELSEAAEAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAE 150
            K I  R + I      +  L +A E Q   ++ +   +     AL  T +      N+  
Sbjct: 999  KVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTS 1058

Query: 151  MKQRDNCKIRIQRQLEIMGKEVSGDQIEDMFEQGKWDVFSENLLADVKGARAALNEIESR 210
             +++   +       E++ K      +      G+W    E    +     +   E++  
Sbjct: 1059 KERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKV- 1117

Query: 211  HRELLRLESRIRDVHELFLQMAVLVEKQADTLNVIELNVQK 251
                  LE ++++  E+   + +  EK    L   E  +QK
Sbjct: 1118 ------LEHKLKEADEMHTLLQLECEKYKSVLAETEGILQK 1152



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 55/263 (20%), Positives = 118/263 (44%), Gaps = 24/263 (9%)

Query: 27  DSPHEDIVFETDHILESLYRDIRDIQD--ENQLLVADVKR-----LGKQNARFLTSMRRL 79
           + P++D+V + +  ++     ++ +++  E  L+    K      +  +N+     ++ L
Sbjct: 723 EQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDL 782

Query: 80  SSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQ---HGPHSAVARISRAQYNAL- 135
            + + D  S A  ++   +VIH K   +K + E  EA+           +  + +  AL 
Sbjct: 783 KAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALK 842

Query: 136 ----TLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDMFEQGKW--DVF 189
                +  ++A      +++++  N     + Q+  M K V  ++ +D+   GKW  D+ 
Sbjct: 843 EEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTM-KAVLEEKEKDLANTGKWLQDLQ 901

Query: 190 SEN--LLADVKG-ARAALNEIESRHR-ELLRLESRIRDVHELFLQMAVLVEKQADTLNVI 245
            EN  L A V+  A+  L E  S  + E L +  + ++ +EL    A+L E+++D  +  
Sbjct: 902 EENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKE-NELKRLEAMLKERESDLSSKT 960

Query: 246 ELNVQKTVDYTGQAKAQVRKAVQ 268
           +L +Q   D     K+Q+ +  Q
Sbjct: 961 QL-LQDVQDENKLFKSQIEQLKQ 982


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 34.7 bits (78), Expect = 0.099
 Identities = 52/277 (18%), Positives = 125/277 (45%), Gaps = 26/277 (9%)

Query: 15   YDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVADVKRL----GKQNA 70
            +++Q  +  D  D   ++++  ++  L+ L  + + IQ+E +LL    + +    G    
Sbjct: 1934 FERQIQEKTDIIDRLEQELLCASNR-LQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQ 1992

Query: 71   RFLTSMRRLSSIKRDTNSIAKAIK--ARGEVIHCKLRAMKELSEAAEAQHGPHSAVARIS 128
            + L    +L   K +    A+ ++   + +V   ++   +++S   E +   ++ +  + 
Sbjct: 1993 QLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDL- 2051

Query: 129  RAQYNALTLTFQR--------AMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM 180
            R Q  AL    ++        A+   ++ ++ Q++  K+  Q ++    + +S  Q  ++
Sbjct: 2052 RQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREV 2111

Query: 181  FE-----QGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLV 235
             +     + K D  SE LL+  +  R    +I+ R+ E+ +LE R+R++ +  L  A   
Sbjct: 2112 EQLANHLKEKTDKCSELLLSKEQLQR----DIQERNEEIEKLEFRVRELEQALLVSADTF 2167

Query: 236  EKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEK 272
            +K  D  +   +  +  +    Q +A+ R A+  +EK
Sbjct: 2168 QKVEDRKHFGAVEAKPELSLEVQLQAE-RDAIDRKEK 2203


>gi|61966741 TMF regulated nuclear protein [Homo sapiens]
          Length = 227

 Score = 34.7 bits (78), Expect = 0.099
 Identities = 19/66 (28%), Positives = 36/66 (54%)

Query: 200 ARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQADTLNVIELNVQKTVDYTGQA 259
           AR  L E+E R R +  LESR+  +H +FL   + +  +A++L+ +   V +   Y    
Sbjct: 106 ARRRLLEVEGRRRLVSELESRVLQLHRVFLAAELRLAHRAESLSRLSGGVAQAELYLAAH 165

Query: 260 KAQVRK 265
            ++++K
Sbjct: 166 GSRLKK 171


>gi|95089461 discs large homolog 5 [Homo sapiens]
          Length = 1919

 Score = 34.3 bits (77), Expect = 0.13
 Identities = 46/259 (17%), Positives = 113/259 (43%), Gaps = 29/259 (11%)

Query: 39  HILESLYRDIRDIQDENQLLVADVKRLGKQ-----------NARFLTSMRRLSSIKRDTN 87
           ++L+  + D++ + +E+Q  + D++   +Q           N  + T+M +L  +K+D +
Sbjct: 259 NLLQQSWEDMKRLHEEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDTAMDKLEVVKKDYD 318

Query: 88  SIAKAIKARGEVIHCKLRAMKELSE-----AAEAQHGPHSAVARISRAQYNALTL-TFQR 141
           ++ K    +  + +  L  +++L E       + +         I      AL+L  F+ 
Sbjct: 319 ALRKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRDTAIQLQHQCALSLRRFEA 378

Query: 142 AMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDMFEQGKWDVFSENLLADVKGAR 201
             H+ N+A  + +D     +Q ++E++  E++  +   +    + + + E   A     +
Sbjct: 379 IHHELNKATAQNKD-----LQWEMELLQSELTELRTTQVKTAKESEKYREERDAVYSEYK 433

Query: 202 AALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQADTLNVIELNVQKTVDY-TGQAK 260
             ++E +    EL +L++ + ++ E  L+ +   +K A+        ++ TV    G+A 
Sbjct: 434 LIMSERDQVISELDKLQTEV-ELAESKLKSSTSEKKAANEEMEALRQIKDTVTMDAGRAN 492

Query: 261 AQVRKAVQYEEKNPCRTLC 279
            +V        +  C+ LC
Sbjct: 493 KEVEIL-----RKQCKALC 506


>gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo
           sapiens]
          Length = 1133

 Score = 33.9 bits (76), Expect = 0.17
 Identities = 44/249 (17%), Positives = 112/249 (44%), Gaps = 37/249 (14%)

Query: 2   KDRLAELLDLS--KQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLV 59
           K R   +L+L   K+  +++ +  DEF    E    E + + + + ++I+  +++ Q   
Sbjct: 166 KSRRQTILELEEEKRKHKEYMEKSDEFICLLEQ---ECERLKKLIDQEIKSQEEKEQ--- 219

Query: 60  ADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHG 119
                  ++  R  T    L+ +K     +    +     +  + + ++EL+  A+  H 
Sbjct: 220 -------EKEKRVTTLKEELTKLKSFALMVVDEQQRLTAQLTLQRQKIQELTTNAKETHT 272

Query: 120 PHS-AVARISRAQYNALTL-----TFQRAMH---DYNQAEMKQRDNCKIRIQRQLEIMGK 170
             + A AR+   +  A  L     T     H   D   A++   D+   ++Q++L  + +
Sbjct: 273 KLALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSR 332

Query: 171 EV------------SGDQIEDMFEQ-GKWDVFSENLLADVKGARAALNEIESRHRELLRL 217
           ++            + ++++D+ E+  K +  +  ++A+V+  R  + ++E +  EL+++
Sbjct: 333 QIDELEETNRSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKM 392

Query: 218 ESRIRDVHE 226
           E + RD+++
Sbjct: 393 EEQCRDLNK 401


>gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo
           sapiens]
          Length = 1135

 Score = 33.9 bits (76), Expect = 0.17
 Identities = 44/249 (17%), Positives = 112/249 (44%), Gaps = 37/249 (14%)

Query: 2   KDRLAELLDLS--KQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLV 59
           K R   +L+L   K+  +++ +  DEF    E    E + + + + ++I+  +++ Q   
Sbjct: 166 KSRRQTILELEEEKRKHKEYMEKSDEFICLLEQ---ECERLKKLIDQEIKSQEEKEQ--- 219

Query: 60  ADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHG 119
                  ++  R  T    L+ +K     +    +     +  + + ++EL+  A+  H 
Sbjct: 220 -------EKEKRVTTLKEELTKLKSFALMVVDEQQRLTAQLTLQRQKIQELTTNAKETHT 272

Query: 120 PHS-AVARISRAQYNALTL-----TFQRAMH---DYNQAEMKQRDNCKIRIQRQLEIMGK 170
             + A AR+   +  A  L     T     H   D   A++   D+   ++Q++L  + +
Sbjct: 273 KLALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSR 332

Query: 171 EV------------SGDQIEDMFEQ-GKWDVFSENLLADVKGARAALNEIESRHRELLRL 217
           ++            + ++++D+ E+  K +  +  ++A+V+  R  + ++E +  EL+++
Sbjct: 333 QIDELEETNRSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKM 392

Query: 218 ESRIRDVHE 226
           E + RD+++
Sbjct: 393 EEQCRDLNK 401


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 33.9 bits (76), Expect = 0.17
 Identities = 61/272 (22%), Positives = 120/272 (44%), Gaps = 79/272 (29%)

Query: 5    LAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVADVKR 64
            +  L ++ K Y+QQ        D  H+++V +  H     ++++ + +D N++  A+ K 
Sbjct: 1541 IESLNEVLKNYNQQK-------DIEHKELVQKLQH-----FQELGEEKD-NRVKEAEEKI 1587

Query: 65   LGKQNARFLTSMR-RLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGPHSA 123
            L  +N  +  SM+  L + K++   +  ++K++ E    +L+A+++  E+  A       
Sbjct: 1588 LTLENQVY--SMKAELETKKKELEHVNLSVKSKEE----ELKALEDRLESESAA------ 1635

Query: 124  VARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIR-IQRQLEIMGKEVSGDQIEDMFE 182
                                     AE+K++   KI  I++QL          Q+E+  E
Sbjct: 1636 -----------------------KLAELKRKAEQKIAAIKKQLL--------SQMEEKEE 1664

Query: 183  QGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQADTL 242
            Q K            KG  + L+E+ ++      L+ R R+VH L  ++  +   Q++TL
Sbjct: 1665 QYK------------KGTESHLSELNTK------LQEREREVHILEEKLKSVESSQSETL 1706

Query: 243  NVIELNVQKTVDYTGQAKAQVRKAVQ--YEEK 272
             ++  + +    YT Q +A  +  VQ  YEEK
Sbjct: 1707 -IVPRSAKNVAAYTEQEEADSQGCVQKTYEEK 1737



 Score = 29.3 bits (64), Expect = 4.2
 Identities = 49/243 (20%), Positives = 96/243 (39%), Gaps = 21/243 (8%)

Query: 2    KDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVAD 61
            K +++EL    K  D++F        S HE    +++  LE    + + + +E   L   
Sbjct: 1168 KRKVSELTSKLKTTDEEF----QSLKSSHE----KSNKSLEDKSLEFKKLSEE---LAIQ 1216

Query: 62   VKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRA--MKELSEAAEAQHG 119
            +    K+    L +  + + +   ++S   AI +R  + HC+ R   +KE          
Sbjct: 1217 LDICCKKTEALLEA--KTNELINISSSKTNAILSR--ISHCQHRTTKVKEALLIKTCTVS 1272

Query: 120  PHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQ---RQLEIMGKEVSGDQ 176
               A  R    + N L ++FQ+A H   + E  Q  + K  I+    + E + KE    Q
Sbjct: 1273 ELEAQLRQLTEEQNTLNISFQQATHQLEEKE-NQIKSMKADIESLVTEKEALQKEGGNQQ 1331

Query: 177  IEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVE 236
                 ++       + L  ++        E++ +  E+  L  ++ D++        L E
Sbjct: 1332 QAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSE 1391

Query: 237  KQA 239
            K+A
Sbjct: 1392 KEA 1394



 Score = 28.5 bits (62), Expect = 7.1
 Identities = 49/236 (20%), Positives = 96/236 (40%), Gaps = 15/236 (6%)

Query: 51  IQDENQLLVADVKRLGKQNARFL-TSMRRLSSIKRDTNSIAKA---IKARGEVIHCKLRA 106
           ++D+  +  A ++ + ++    L      L S+  + + + KA   ++    V+  +   
Sbjct: 657 LKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDK 716

Query: 107 MKELSEAAEAQHGPH--SAVARISRAQYNALTLTFQRAMHDYNQAEM--KQRDNCKIRIQ 162
           MK+  EA   +   H    V  I +    ++  T +      NQ E+  K+RD      Q
Sbjct: 717 MKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQ 776

Query: 163 RQLEIMGKEVSGDQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESR-- 220
             +E +  ++   + E      K DVF     A  +  +A   ++    ++LL LE+   
Sbjct: 777 AHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERI 836

Query: 221 --IRDVHELFLQMA-VLVEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQ-YEEK 272
              + V E+  Q   V  E  A  + V +L +Q+      + + +V+   Q YE K
Sbjct: 837 LLTKQVAEVEAQKKDVCTELDAHKIQVQDL-MQQLEKQNSEMEQKVKSLTQVYESK 891


>gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo
           sapiens]
          Length = 987

 Score = 33.1 bits (74), Expect = 0.29
 Identities = 50/282 (17%), Positives = 115/282 (40%), Gaps = 54/282 (19%)

Query: 39  HILESLYRDIRDIQDENQLLVADVKRLGKQNAR---FLTSMRR---------------LS 80
           +I + L   +R +++ENQ  +  +KRL ++N +   FL   R                L 
Sbjct: 405 NIQQQLTCSLRKVEEENQGALEMIKRLKEENEKLNEFLELERHNNNMMAKTLEECRVTLE 464

Query: 81  SIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGPHSAVARISRAQYNALTLTFQ 140
            +K +  S+   ++   +    +  A+++ +E+ E Q      + +++RA+ + L L+  
Sbjct: 465 GLKMENGSLKSHLQGEKQKA-TEASAVEQTAESCEVQE-----MLKVARAEKDLLELSCN 518

Query: 141 RAMHDYNQA--EMKQRDNCKIRIQRQLEIMGKEVSGDQIEDMFEQG-KWDVFSENLLADV 197
               +  +A  E+K   +   ++++    + KE+   Q E +     K    +    A++
Sbjct: 519 ELRQELLKANGEIKHVSSLLAKVEKDYSYL-KEICDHQAEQLSRTSLKLQEKASESDAEI 577

Query: 198 KGARAALNEIE---SRHR---------------ELLRLESRIRDVHELFLQMAVLVEKQA 239
           K  +  + E+E    +HR                +++LE +  D+      +   ++++ 
Sbjct: 578 KDMKETIFELEDQVEQHRAVKLHNNQLISELESSVIKLEEQKSDLERQLKTLTKQMKEET 637

Query: 240 DTLNVIELNVQKTVDYTGQAKAQV--------RKAVQYEEKN 273
           +     + ++Q  V      K +         RK ++ EEKN
Sbjct: 638 EEWRRFQADLQTAVVVANDIKCEAQQELRTVKRKLLEEEEKN 679


>gi|75750468 spectrin domain with coiled-coils 1 NSP5a3a [Homo
           sapiens]
          Length = 709

 Score = 33.1 bits (74), Expect = 0.29
 Identities = 50/282 (17%), Positives = 115/282 (40%), Gaps = 54/282 (19%)

Query: 39  HILESLYRDIRDIQDENQLLVADVKRLGKQNAR---FLTSMRR---------------LS 80
           +I + L   +R +++ENQ  +  +KRL ++N +   FL   R                L 
Sbjct: 405 NIQQQLTCSLRKVEEENQGALEMIKRLKEENEKLNEFLELERHNNNMMAKTLEECRVTLE 464

Query: 81  SIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGPHSAVARISRAQYNALTLTFQ 140
            +K +  S+   ++   +    +  A+++ +E+ E Q      + +++RA+ + L L+  
Sbjct: 465 GLKMENGSLKSHLQGEKQKA-TEASAVEQTAESCEVQE-----MLKVARAEKDLLELSCN 518

Query: 141 RAMHDYNQA--EMKQRDNCKIRIQRQLEIMGKEVSGDQIEDMFEQG-KWDVFSENLLADV 197
               +  +A  E+K   +   ++++    + KE+   Q E +     K    +    A++
Sbjct: 519 ELRQELLKANGEIKHVSSLLAKVEKDYSYL-KEICDHQAEQLSRTSLKLQEKASESDAEI 577

Query: 198 KGARAALNEIE---SRHR---------------ELLRLESRIRDVHELFLQMAVLVEKQA 239
           K  +  + E+E    +HR                +++LE +  D+      +   ++++ 
Sbjct: 578 KDMKETIFELEDQVEQHRAVKLHNNQLISELESSVIKLEEQKSDLERQLKTLTKQMKEET 637

Query: 240 DTLNVIELNVQKTVDYTGQAKAQV--------RKAVQYEEKN 273
           +     + ++Q  V      K +         RK ++ EEKN
Sbjct: 638 EEWRRFQADLQTAVVVANDIKCEAQQELRTVKRKLLEEEEKN 679


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.133    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,896,754
Number of Sequences: 37866
Number of extensions: 319359
Number of successful extensions: 1561
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 74
Number of HSP's that attempted gapping in prelim test: 1485
Number of HSP's gapped (non-prelim): 155
length of query: 287
length of database: 18,247,518
effective HSP length: 101
effective length of query: 186
effective length of database: 14,423,052
effective search space: 2682687672
effective search space used: 2682687672
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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