Guide to the Human Genome
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Name: CHRNA5 Sequence: fasta or formatted (468aa) NCBI GI: 33589827
Description:

cholinergic receptor, nicotinic, alpha 5

Referenced in:

Acetylcholine

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.5         21           2
 C cysteine            1.9          9           2
 D aspartate           6.0         28           2
 E glutamate           4.7         22           2
 F phenylalanine       5.6         26           2
 G glycine             5.8         27           2
 H histidine           1.9          9           2
 I isoleucine          7.9         37           2
 K lysine              5.3         25           1
 L leucine            10.5         49           4
 M methionine          1.9          9           1
 N asparagine          3.8         18           1
 P proline             4.3         20           2
 Q glutamine           2.4         11           1
 R arginine            4.9         23           1
 S serine              7.9         37           3
 T threonine           6.2         29           2
 V valine              9.0         42           2
 W tryptophan          2.6         12           1
 Y tyrosine            3.0         14           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   cholinergic receptor, nicotinic, alpha 5 
CHRNB3                0.635   cholinergic receptor, nicotinic, beta polypeptide 3 [...
CHRNA2                0.462   cholinergic receptor, nicotinic, alpha polypeptide ...
CHRNA6                0.434   cholinergic receptor, nicotinic, alpha 6 
CHRNA4                0.426   cholinergic receptor, nicotinic, alpha 4 subunit prec...
CHRNA3                0.398   cholinergic receptor, nicotinic, alpha 3 
CHRNA1                0.391   nicotinic cholinergic receptor alpha 1 isoform b prec...
CHRNB4                0.389   cholinergic receptor, nicotinic, beta 4 
CHRNA1                0.376   nicotinic cholinergic receptor alpha 1 isoform a pre...
CHRNB2                0.373   neuronal nicotinic acetylcholine receptor beta 2 prec...
CHRNB1                0.297   nicotinic acetylcholine receptor beta 1 subunit prec...
CHRND                 0.285   nicotinic acetylcholine receptor delta polypeptide pr...
CHRNA9                0.282   cholinergic receptor, nicotinic, alpha 9 precursor [...
CHRNA10               0.277   cholinergic receptor, nicotinic, alpha 10 
CHRNA7                0.274   cholinergic receptor, nicotinic, alpha 7 precursor [H...
CHRNE                 0.244   nicotinic acetylcholine receptor epsilon polypeptide ...
CHRNG                 0.243   cholinergic receptor, nicotinic, gamma polypeptide p...
HTR3A                 0.203   5-hydroxytryptamine (serotonin) receptor 3A isoform...
HTR3A                 0.203   5-hydroxytryptamine (serotonin) receptor 3A isoform...
HTR3A                 0.186   5-hydroxytryptamine (serotonin) receptor 3A isoform...
CHRFAM7A              0.176   CHRNA7-FAM7A fusion isoform 1 
HTR3B                 0.159   5-hydroxytryptamine (serotonin) receptor 3B precursor...
HTR3E                 0.131   5-hydroxytryptamine receptor 3 subunit E 
HTR3C                 0.121   5-hydroxytryptamine receptor 3 subunit C 
CHRFAM7A              0.110   CHRNA7-FAM7A fusion isoform 2 
GABRP                 0.054   gamma-aminobutyric acid (GABA) A receptor, pi 
GABRB3                0.051   gamma-aminobutyric acid (GABA) A receptor, beta 3 is...
GLRB                  0.048   glycine receptor, beta 
GABRA2                0.046   gamma-aminobutyric acid A receptor, alpha 2 
GABRA2                0.046   gamma-aminobutyric acid A receptor, alpha 2 precurs...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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