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Search of human proteins with 33589814
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33589814 zyg-11 homolog B (C. elegans)-like [Homo sapiens]
(766 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33589814 zyg-11 homolog B (C. elegans)-like [Homo sapiens] 1535 0.0
gi|55742693 zyg-11 homolog B [Homo sapiens] 257 3e-68
gi|113408672 PREDICTED: zyg-11 homolog A [Homo sapiens] 196 9e-50
gi|226437632 zyg-11 homolog A [Homo sapiens] 196 9e-50
gi|169160755 PREDICTED: zyg-11 homolog A (C. elegans) [Homo sapi... 168 2e-41
gi|88948888 PREDICTED: zyg-11 homolog A (C. elegans) [Homo sapiens] 168 2e-41
gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 ... 38 0.040
gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo ... 37 0.069
gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo ... 37 0.069
gi|66472382 nischarin [Homo sapiens] 35 0.26
gi|15529984 armadillo repeat containing 6 [Homo sapiens] 34 0.58
gi|224500884 hypothetical protein LOC339541 [Homo sapiens] 33 0.76
gi|7662320 leucine-rich repeats and immunoglobulin-like domains ... 33 0.76
gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens] 33 1.3
gi|21327710 nucleosome assembly protein 1-like 3 [Homo sapiens] 32 1.7
gi|99028953 inscuteable isoform a [Homo sapiens] 32 1.7
gi|110227584 inscuteable isoform b [Homo sapiens] 32 1.7
gi|53729344 plakophilin 1 isoform 1a [Homo sapiens] 32 2.2
gi|169218113 PREDICTED: similar to plakophilin 1, partial [Homo ... 32 2.2
gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 ... 32 2.2
gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens] 32 2.2
gi|122937470 carboxypeptidase N, polypeptide 2, 83kD [Homo sapiens] 32 2.9
gi|53729346 plakophilin 1 isoform 1b [Homo sapiens] 31 3.8
gi|76880480 hypothetical protein LOC9865 [Homo sapiens] 31 3.8
gi|194294510 kinesin family member C3 isoform 2 [Homo sapiens] 31 4.9
gi|194294508 kinesin family member C3 isoform 3 [Homo sapiens] 31 4.9
gi|94536858 kinesin family member C3 isoform 1 [Homo sapiens] 31 4.9
gi|4826952 proteasome 26S non-ATPase subunit 5 [Homo sapiens] 31 4.9
gi|21071028 acidic nuclear phosphoprotein 32D [Homo sapiens] 31 4.9
gi|189011568 adenomatous polyposis coli [Homo sapiens] 30 6.4
>gi|33589814 zyg-11 homolog B (C. elegans)-like [Homo sapiens]
Length = 766
Score = 1535 bits (3975), Expect = 0.0
Identities = 766/766 (100%), Positives = 766/766 (100%)
Query: 1 MASDTPESLMALCTDFCLRNLDGTLGYLLDKETLRLHPDIFLPSEICDRLVNEYVELVNA 60
MASDTPESLMALCTDFCLRNLDGTLGYLLDKETLRLHPDIFLPSEICDRLVNEYVELVNA
Sbjct: 1 MASDTPESLMALCTDFCLRNLDGTLGYLLDKETLRLHPDIFLPSEICDRLVNEYVELVNA 60
Query: 61 ACNFEPHESFFSLFSDPRSTRLTRIHLREDLVQDQDLEAIRKQDLVELYLTNCEKLSAKS 120
ACNFEPHESFFSLFSDPRSTRLTRIHLREDLVQDQDLEAIRKQDLVELYLTNCEKLSAKS
Sbjct: 61 ACNFEPHESFFSLFSDPRSTRLTRIHLREDLVQDQDLEAIRKQDLVELYLTNCEKLSAKS 120
Query: 121 LQTLRSFSHTLVSLSLFGCTNIFYEEENPGGCEDEYLVNPTCQVLVKDFTFEGFSRLRFL 180
LQTLRSFSHTLVSLSLFGCTNIFYEEENPGGCEDEYLVNPTCQVLVKDFTFEGFSRLRFL
Sbjct: 121 LQTLRSFSHTLVSLSLFGCTNIFYEEENPGGCEDEYLVNPTCQVLVKDFTFEGFSRLRFL 180
Query: 181 NLGRMIDWVPVESLLRPLNSLAALDLSGIQTSDAAFLTQWKDSLVSLVLYNMDLSDDHIR 240
NLGRMIDWVPVESLLRPLNSLAALDLSGIQTSDAAFLTQWKDSLVSLVLYNMDLSDDHIR
Sbjct: 181 NLGRMIDWVPVESLLRPLNSLAALDLSGIQTSDAAFLTQWKDSLVSLVLYNMDLSDDHIR 240
Query: 241 VIVQLHKLRHLDISRDRLSSYYKFKLTREVLSLFVQKLGNLMSLDISGHMILENCSISKM 300
VIVQLHKLRHLDISRDRLSSYYKFKLTREVLSLFVQKLGNLMSLDISGHMILENCSISKM
Sbjct: 241 VIVQLHKLRHLDISRDRLSSYYKFKLTREVLSLFVQKLGNLMSLDISGHMILENCSISKM 300
Query: 301 EEEAGQTSIEPSKSSIIPFRALKRPLQFLGLFENSLCRLTHIPAYKVSGDKNEEQVLNAI 360
EEEAGQTSIEPSKSSIIPFRALKRPLQFLGLFENSLCRLTHIPAYKVSGDKNEEQVLNAI
Sbjct: 301 EEEAGQTSIEPSKSSIIPFRALKRPLQFLGLFENSLCRLTHIPAYKVSGDKNEEQVLNAI 360
Query: 361 EAYTEHRPEITSRAINLLFDIARIERCNQLLRALKLVITALKCHKYDRNIQVTGSAALFY 420
EAYTEHRPEITSRAINLLFDIARIERCNQLLRALKLVITALKCHKYDRNIQVTGSAALFY
Sbjct: 361 EAYTEHRPEITSRAINLLFDIARIERCNQLLRALKLVITALKCHKYDRNIQVTGSAALFY 420
Query: 421 LTNSEYRSEQSVKLRRQVIQVVLNGMESYQEVTVQRNCCLTLCNFSIPEELEFQYRRVNE 480
LTNSEYRSEQSVKLRRQVIQVVLNGMESYQEVTVQRNCCLTLCNFSIPEELEFQYRRVNE
Sbjct: 421 LTNSEYRSEQSVKLRRQVIQVVLNGMESYQEVTVQRNCCLTLCNFSIPEELEFQYRRVNE 480
Query: 481 LLLSILNPTRQDESIQRIAVHLCNALVCQVDNDHKEAVGKMGFVVTMLKLIQKKLLDKTC 540
LLLSILNPTRQDESIQRIAVHLCNALVCQVDNDHKEAVGKMGFVVTMLKLIQKKLLDKTC
Sbjct: 481 LLLSILNPTRQDESIQRIAVHLCNALVCQVDNDHKEAVGKMGFVVTMLKLIQKKLLDKTC 540
Query: 541 DQVMEFSWSALWNITDETPDNCEMFLNFNGMKLFLDCLKEFPEKQELHRNMLGLLGNVAE 600
DQVMEFSWSALWNITDETPDNCEMFLNFNGMKLFLDCLKEFPEKQELHRNMLGLLGNVAE
Sbjct: 541 DQVMEFSWSALWNITDETPDNCEMFLNFNGMKLFLDCLKEFPEKQELHRNMLGLLGNVAE 600
Query: 601 VKELRPQLMTSQFISVFSNLLESKADGIEVSYNACGVLSHIMFDGPEAWGVCEPQREEVE 660
VKELRPQLMTSQFISVFSNLLESKADGIEVSYNACGVLSHIMFDGPEAWGVCEPQREEVE
Sbjct: 601 VKELRPQLMTSQFISVFSNLLESKADGIEVSYNACGVLSHIMFDGPEAWGVCEPQREEVE 660
Query: 661 ERMWAAIQSWDINSRRNINYRSFEPILRLLPQGISPVSQHWATWALYNLVSVYPDKYCPL 720
ERMWAAIQSWDINSRRNINYRSFEPILRLLPQGISPVSQHWATWALYNLVSVYPDKYCPL
Sbjct: 661 ERMWAAIQSWDINSRRNINYRSFEPILRLLPQGISPVSQHWATWALYNLVSVYPDKYCPL 720
Query: 721 LIKEGGMPLLRDIIKMATARQETKEMARKVIEHCSNFKEENMDTSR 766
LIKEGGMPLLRDIIKMATARQETKEMARKVIEHCSNFKEENMDTSR
Sbjct: 721 LIKEGGMPLLRDIIKMATARQETKEMARKVIEHCSNFKEENMDTSR 766
>gi|55742693 zyg-11 homolog B [Homo sapiens]
Length = 744
Score = 257 bits (656), Expect = 3e-68
Identities = 211/755 (27%), Positives = 358/755 (47%), Gaps = 85/755 (11%)
Query: 1 MASDTPESLMALCTDFCLRNLDGTLGYLLDKETLRLHPDIFLPSEICDRLVNEYVELVNA 60
M +P SL+ +C +F +L+ D P +F P E+ DRL+
Sbjct: 10 MEEASPYSLLDICLNFLTTHLEKFCSARQDGTLCLQEPGVF-PQEVADRLLRTM------ 62
Query: 61 ACNFEPHESFFSLFSDPRST--RLTRIHLREDLVQDQDLEAI--RK----QDLVELYLT- 111
+F L +D R ++ L+ ++ + A+ RK LVEL T
Sbjct: 63 --------AFHGLLNDGTVGIFRGNQMRLKRACIRKAKISAVAFRKAFCHHKLVELDATG 114
Query: 112 -NCEKLSAKSLQTLRSFSHTLVSLSLFGCTNIFYEEENPGGCEDEYLVNPTCQVLVKDFT 170
N + + L S +L ++ E+P +
Sbjct: 115 VNADITITDIISGLGSNKWIQQNLQCLVLNSLTLSLEDP-----------------YERC 157
Query: 171 FEGFSRLRFLNLGRMIDWVPVESLLRPLNSLAALDLSGIQTSDAAFLTQWKDSLVSLVLY 230
F S LR L++ ++ + + + L L +LD+S +D L KD L SL ++
Sbjct: 158 FSRLSGLRALSITNVLFYNEDLAEVASLPRLESLDISNTSITDITALLACKDRLKSLTMH 217
Query: 231 NMDL----SDDHIRVIVQLHKLRHLDISRDRLSSYYKFKLTREV-LSLFVQK--LGNLMS 283
++ + + V+ +L L HLDIS D+ + T ++ L L QK L NL+S
Sbjct: 218 HLKCLKMTTTQILDVVRELKHLNHLDISDDK-------QFTSDIALRLLEQKDILPNLVS 270
Query: 284 LDISGHMILENCSISKMEEEAGQTSIEPSKSSIIPFRALKRPLQFLGLFENSLCR---LT 340
LD+SG + ++A + I+ S +QF+GL LT
Sbjct: 271 LDVSGR--------KHVTDKAVEAFIQQRPS-----------MQFVGLLATDAGYSEFLT 311
Query: 341 HIPAYKVSGDKNEEQVLNAIEAYTEHRPEITSRAINLLFDIARIERCNQLLRALKLVITA 400
KVSG+ NE Q+ A++ Y+E R A+ LF + + + LKLV+T
Sbjct: 312 GEGHLKVSGEANETQIAEALKRYSE-RAFFVREALFHLFSLTHVMEKTKP-EILKLVVTG 369
Query: 401 LKCHKYDRNIQVTGSAALFYLTNSEYRSEQSVKLRRQVIQVVLNGMESY-QEVTVQRNCC 459
++ H + +Q+ SA +F LT + + V+L V ++L ME + +Q+NC
Sbjct: 370 MRNHPMNLPVQLAASACVFNLTKQDLAAGMPVRLLADVTHLLLKAMEHFPNHQQLQKNCL 429
Query: 460 LTLCNFSIPEELEFQYRRVNELLLSILNPTRQDESIQRIAVHLCNALVCQVDNDHKEAVG 519
L+LC+ I +++ F +L++ L +D+++QR+AV + + L ++ + +G
Sbjct: 430 LSLCSDRILQDVPFNRFEAAKLVMQWLC-NHEDQNMQRMAVAIISILAAKLSTEQTAQLG 488
Query: 520 KMGFVVT-MLKLIQKKLLDKTCDQVMEFSWSALWNITDETPDNCEMFLNFNGMKLFLDCL 578
F+V +L+++++K + D ++F+ SALWN+TDE+P C F+ G++LF+ L
Sbjct: 489 TELFIVRQLLQIVKQKTNQNSVDTTLKFTLSALWNLTDESPTTCRHFIENQGLELFMRVL 548
Query: 579 KEFPEKQELHRNMLGLLGNVAEVKELRPQLMTSQFISVFSNLLESKADGIEVSYNACGVL 638
+ FP + + + +LGLL N+AEV+EL +LM FI S+LL S +EVSY A G++
Sbjct: 549 ESFPTESSIQQKVLGLLNNIAEVQELHSELMWKDFIDHISSLLHSVE--VEVSYFAAGII 606
Query: 639 SHIMFDGPEAWGVCEPQREEVEERMWAAIQSWDINSRRNINYRSFEPILRLLPQGISPVS 698
+H++ G +AW + QR + + + +AI W + YRSF P LL +P
Sbjct: 607 AHLISRGEQAWTLSRSQRNSLLDDLHSAILKWPTPECEMVAYRSFNPFFPLLGCFTTPGV 666
Query: 699 QHWATWALYNLVSVYPDKYCPLLIKEGGMPLLRDI 733
Q WA WA+ ++ S P +YC +LI+EGG+ L +I
Sbjct: 667 QLWAVWAMQHVCSKNPSRYCSMLIEEGGLQHLYNI 701
>gi|113408672 PREDICTED: zyg-11 homolog A [Homo sapiens]
Length = 759
Score = 196 bits (497), Expect = 9e-50
Identities = 186/718 (25%), Positives = 331/718 (46%), Gaps = 62/718 (8%)
Query: 74 FSDPRSTRLTRIHLREDLVQDQDLEAIRKQDLVELYLTNCEKLSAKSLQTLRSFS-HTLV 132
F + R R+ + + D+ R + +L L N +K + +++F H L+
Sbjct: 70 FPQEVAERFLRVMTWQGKLTDRTASIFRGNQM-KLKLVNIQKAKISTAAFIKAFCRHKLI 128
Query: 133 SLSLFGC-TNIFYEEENPGGCEDEYLVNPTCQVLVKDFT----------FEGFSRLRFLN 181
L+ ++ + G C + + + Q L+ D T F + LR L+
Sbjct: 129 ELNATAVHADLPVPDIISGLCSNRW-IQQNLQCLLLDSTSIPQNSRLLFFSQLTGLRILS 187
Query: 182 LGRMIDWVPVESLLRPLNSLAALDLSGIQTSDAAFLTQWKDSLVSLVLYNMDL----SDD 237
+ + + + L L +LD+S +D + L KD L SL ++ +
Sbjct: 188 VFNVCFHTEDLANVSQLPRLESLDISNTLVTDISALLTCKDRLKSLTMHYLKCLAMTKSQ 247
Query: 238 HIRVIVQLHKLRHLDISRDR-LSSYYKFKLTREVLSLFVQKLGNLMSLDISGHMILENCS 296
+ VI +L L HLDIS R L S F L ++ L N++SLDISG NC
Sbjct: 248 ILAVIRELKCLLHLDISDHRQLKSDLAFHLLQQK-----DILPNVVSLDISGG----NC- 297
Query: 297 ISKMEEEAGQTSIEPSKSSIIPFRALKRPLQFLGLFEN---SLCRLTHIPAYKVSGDKNE 353
+ +EA + I L+ +QF+GL S T +V+G +
Sbjct: 298 ---ITDEAVELFIR-----------LRPAMQFVGLLATDAGSSDFFTTKQGLRVAGGASM 343
Query: 354 EQVLNAIEAYTEHRPEITSRAINLLFDIARIERCNQLLRALKLVITALKCHKYDRNIQVT 413
Q+ A+ Y +R A++ LF + LKLV ++ H D +Q T
Sbjct: 344 SQISEALSRY-RNRSCFVKEALHRLFTETFSMEVT-MPAILKLVAIGMRNHPLDLRVQFT 401
Query: 414 GSAALFYLTNSEYRSEQSVKLRRQVIQVVLNGMESYQEVT-VQRNCCLTLCNFSIPEELE 472
SA LT V+L +V ++ ++++ +Q+NC L+L N I ++
Sbjct: 402 ASACALNLTRQGLAKGMPVRLLSEVTCLLFKALKNFPHYQQLQKNCLLSLTNSRILVDVP 461
Query: 473 FQYRRVNELLLSILNPTRQDESIQRIAVHLCNALVCQVDNDHKEAVGKMGFVVT-MLKLI 531
F + ++ L ++ +Q +AV + + L Q+ + + ++ V +L ++
Sbjct: 462 FDRFDAAKFVMRWLCK-HENPKMQTMAVSVTSILALQLSPEQTAQLEELFMAVKELLAIV 520
Query: 532 QKKLLDKTCDQVMEFSWSALWNITDETPDNCEMFLNFNGMKLFLDCLKEFPEKQELHRNM 591
++K + D F+ ALWN+TD +P C+ F+ G+++F+ L+ F E + +
Sbjct: 521 KQKTTENLDDVTFLFTLKALWNLTDGSPAACKHFIENQGLQIFIQVLETFSESA-IQSKV 579
Query: 592 LGLLGNVAEVKELRPQLMTSQFISVFSNLLESKADGIEVSYNACGVLSHIMFDGPEAWGV 651
LGLL N+AEV+EL +L+T + ++LL S+ +EVSY A G+++H+ D + W
Sbjct: 580 LGLLNNIAEVRELSSKLVTEDVLKHINSLLCSRE--MEVSYFAAGIIAHLTSDR-QLWIS 636
Query: 652 CEPQREEVEERMWAAIQSWDINSRRN---INYRSFEPILRLLPQGISPVSQHWATWALYN 708
+ QR + + + A IQ+W +S + + YRSF+ LL P Q WA WA+Y+
Sbjct: 637 RDFQRRTLLQDLHATIQNWPSSSCKMTALVTYRSFKTFFPLLGNFSQPEVQLWALWAMYH 696
Query: 709 LVSVYPDKYCPLLIKEGGMPLLRDIIKMATARQETKEMARKVIE----HCSNFKEENM 762
+ S P KYC +L++E G+ LL DI + + A + +++A +++ H N++ +
Sbjct: 697 VCSKNPSKYCKMLVEEEGLQLLCDIQEHSEATPKAQQIAASILDDFRMHFMNYQRPTL 754
>gi|226437632 zyg-11 homolog A [Homo sapiens]
Length = 759
Score = 196 bits (497), Expect = 9e-50
Identities = 186/718 (25%), Positives = 331/718 (46%), Gaps = 62/718 (8%)
Query: 74 FSDPRSTRLTRIHLREDLVQDQDLEAIRKQDLVELYLTNCEKLSAKSLQTLRSFS-HTLV 132
F + R R+ + + D+ R + +L L N +K + +++F H L+
Sbjct: 70 FPQEVAERFLRVMTWQGKLTDRTASIFRGNQM-KLKLVNIQKAKISTAAFIKAFCRHKLI 128
Query: 133 SLSLFGC-TNIFYEEENPGGCEDEYLVNPTCQVLVKDFT----------FEGFSRLRFLN 181
L+ ++ + G C + + + Q L+ D T F + LR L+
Sbjct: 129 ELNATAVHADLPVPDIISGLCSNRW-IQQNLQCLLLDSTSIPQNSRLLFFSQLTGLRILS 187
Query: 182 LGRMIDWVPVESLLRPLNSLAALDLSGIQTSDAAFLTQWKDSLVSLVLYNMDL----SDD 237
+ + + + L L +LD+S +D + L KD L SL ++ +
Sbjct: 188 VFNVCFHTEDLANVSQLPRLESLDISNTLVTDISALLTCKDRLKSLTMHYLKCLAMTKSQ 247
Query: 238 HIRVIVQLHKLRHLDISRDR-LSSYYKFKLTREVLSLFVQKLGNLMSLDISGHMILENCS 296
+ VI +L L HLDIS R L S F L ++ L N++SLDISG NC
Sbjct: 248 ILAVIRELKCLLHLDISDHRQLKSDLAFHLLQQK-----DILPNVVSLDISGG----NC- 297
Query: 297 ISKMEEEAGQTSIEPSKSSIIPFRALKRPLQFLGLFEN---SLCRLTHIPAYKVSGDKNE 353
+ +EA + I L+ +QF+GL S T +V+G +
Sbjct: 298 ---ITDEAVELFIR-----------LRPAMQFVGLLATDAGSSDFFTTKQGLRVAGGASM 343
Query: 354 EQVLNAIEAYTEHRPEITSRAINLLFDIARIERCNQLLRALKLVITALKCHKYDRNIQVT 413
Q+ A+ Y +R A++ LF + LKLV ++ H D +Q T
Sbjct: 344 SQISEALSRY-RNRSCFVKEALHRLFTETFSMEVT-MPAILKLVAIGMRNHPLDLRVQFT 401
Query: 414 GSAALFYLTNSEYRSEQSVKLRRQVIQVVLNGMESYQEVT-VQRNCCLTLCNFSIPEELE 472
SA LT V+L +V ++ ++++ +Q+NC L+L N I ++
Sbjct: 402 ASACALNLTRQGLAKGMPVRLLSEVTCLLFKALKNFPHYQQLQKNCLLSLTNSRILVDVP 461
Query: 473 FQYRRVNELLLSILNPTRQDESIQRIAVHLCNALVCQVDNDHKEAVGKMGFVVT-MLKLI 531
F + ++ L ++ +Q +AV + + L Q+ + + ++ V +L ++
Sbjct: 462 FDRFDAAKFVMRWLCK-HENPKMQTMAVSVTSILALQLSPEQTAQLEELFMAVKELLAIV 520
Query: 532 QKKLLDKTCDQVMEFSWSALWNITDETPDNCEMFLNFNGMKLFLDCLKEFPEKQELHRNM 591
++K + D F+ ALWN+TD +P C+ F+ G+++F+ L+ F E + +
Sbjct: 521 KQKTTENLDDVTFLFTLKALWNLTDGSPAACKHFIENQGLQIFIQVLETFSESA-IQSKV 579
Query: 592 LGLLGNVAEVKELRPQLMTSQFISVFSNLLESKADGIEVSYNACGVLSHIMFDGPEAWGV 651
LGLL N+AEV+EL +L+T + ++LL S+ +EVSY A G+++H+ D + W
Sbjct: 580 LGLLNNIAEVRELSSKLVTEDVLKHINSLLCSRE--MEVSYFAAGIIAHLTSDR-QLWIS 636
Query: 652 CEPQREEVEERMWAAIQSWDINSRRN---INYRSFEPILRLLPQGISPVSQHWATWALYN 708
+ QR + + + A IQ+W +S + + YRSF+ LL P Q WA WA+Y+
Sbjct: 637 RDFQRRTLLQDLHATIQNWPSSSCKMTALVTYRSFKTFFPLLGNFSQPEVQLWALWAMYH 696
Query: 709 LVSVYPDKYCPLLIKEGGMPLLRDIIKMATARQETKEMARKVIE----HCSNFKEENM 762
+ S P KYC +L++E G+ LL DI + + A + +++A +++ H N++ +
Sbjct: 697 VCSKNPSKYCKMLVEEEGLQLLCDIQEHSEATPKAQQIAASILDDFRMHFMNYQRPTL 754
>gi|169160755 PREDICTED: zyg-11 homolog A (C. elegans) [Homo
sapiens]
Length = 736
Score = 168 bits (425), Expect = 2e-41
Identities = 171/663 (25%), Positives = 300/663 (45%), Gaps = 58/663 (8%)
Query: 74 FSDPRSTRLTRIHLREDLVQDQDLEAIRKQDLVELYLTNCEKLSAKSLQTLRSFS-HTLV 132
F + R R+ + + D+ R + +L L N +K + +++F H L+
Sbjct: 70 FPQEVADRFLRVMTWQGKLTDRTASIFRGNQM-KLKLVNIQKAKISTAAFIKAFCRHKLI 128
Query: 133 SLSLFGC-TNIFYEEENPGGCEDEYLVNPTCQVLVKDFT----------FEGFSRLRFLN 181
L+ ++ + G C + + + Q L+ D T F + LR L+
Sbjct: 129 ELNATAVHADLPVPDIISGLCSNRW-IQQNLQCLLLDSTSIPQNSRLLFFSQLTGLRILS 187
Query: 182 LGRMIDWVPVESLLRPLNSLAALDLSGIQTSDAAFLTQWKDSLVSLVLYNMDL----SDD 237
+ + + + L L +LD+S +D + L KD L SL ++ +
Sbjct: 188 VFNVCFHTEDLANVSQLPRLESLDISNTLVTDISALLTCKDRLKSLTMHYLKCLAMTKSQ 247
Query: 238 HIRVIVQLHKLRHLDISRDR-LSSYYKFKLTREVLSLFVQKLGNLMSLDISGHMILENCS 296
+ VI +L L HLDIS R L S F L ++ L N++SLDISG NC
Sbjct: 248 ILAVIRELKCLLHLDISDHRQLKSDLAFHLLQQK-----DILPNVVSLDISGG----NC- 297
Query: 297 ISKMEEEAGQTSIEPSKSSIIPFRALKRPLQFLGLFEN---SLCRLTHIPAYKVSGDKNE 353
+ +EA + I L+ +QF+GL S T +V+G +
Sbjct: 298 ---ITDEAVELFIR-----------LRPAMQFVGLLATDAGSSDFFTTKQGLRVAGGASM 343
Query: 354 EQVLNAIEAYTEHRPEITSRAINLLFDIARIERCNQLLRALKLVITALKCHKYDRNIQVT 413
Q+ A+ Y +R A++ LF + LKLV ++ H D +Q T
Sbjct: 344 SQISEALSRY-RNRSCFVKEALHRLFTETFSMEVT-MPAILKLVAIGMRNHPLDLRVQFT 401
Query: 414 GSAALFYLTNSEYRSEQSVKLRRQVIQVVLNGMESYQEVT-VQRNCCLTLCNFSIPEELE 472
SA LT V+L +V ++ ++++ +Q+NC L+L N I ++
Sbjct: 402 ASACALNLTRQGLAKGMPVRLLSEVTCLLFKALKNFPHYQQLQKNCLLSLTNSRILVDVP 461
Query: 473 FQYRRVNELLLSILNPTRQDESIQRIAVHLCNALVCQVDNDHKEAVGKMGFVVT-MLKLI 531
F + ++ L ++ +Q +AV + + L Q+ + + ++ V +L ++
Sbjct: 462 FDRFDAAKFVMRWLCK-HENPKMQTMAVSVTSILALQLSPEQTAQLEELFMAVKELLAIV 520
Query: 532 QKKLLDKTCDQVMEFSWSALWNITDETPDNCEMFLNFNGMKLFLDCLKEFPEKQELHRNM 591
++K + D F+ ALWN+TD +P C+ F+ G+++F+ L+ F E + +
Sbjct: 521 KQKTTENLDDVTFLFTLKALWNLTDGSPAACKHFIENQGLQIFIQVLETFSE-SAIQSKV 579
Query: 592 LGLLGNVAEVKELRPQLMTSQFISVFSNLLESKADGIEVSYNACGVLSHIMFDGPEAWGV 651
LGLL N+AEV+EL +L+T + ++LL S+ +EVSY A G+++H+ D + W
Sbjct: 580 LGLLNNIAEVRELSSKLVTEDVLKHINSLLCSRE--MEVSYFAAGIIAHLTSD-RQLWIS 636
Query: 652 CEPQREEVEERMWAAIQSWDINSRRN---INYRSFEPILRLLPQGISPVSQHWATWALYN 708
+ QR + + + A IQ+W +S + + YRSF+ LL P Q WA WA+Y+
Sbjct: 637 RDFQRRTLLQDLHATIQNWPSSSCKMTALVTYRSFKTFFPLLGNFSQPEVQLWALWAMYH 696
Query: 709 LVS 711
+ S
Sbjct: 697 VCS 699
>gi|88948888 PREDICTED: zyg-11 homolog A (C. elegans) [Homo sapiens]
Length = 736
Score = 168 bits (425), Expect = 2e-41
Identities = 171/663 (25%), Positives = 300/663 (45%), Gaps = 58/663 (8%)
Query: 74 FSDPRSTRLTRIHLREDLVQDQDLEAIRKQDLVELYLTNCEKLSAKSLQTLRSFS-HTLV 132
F + R R+ + + D+ R + +L L N +K + +++F H L+
Sbjct: 70 FPQEVADRFLRVMTWQGKLTDRTASIFRGNQM-KLKLVNIQKAKISTAAFIKAFCRHKLI 128
Query: 133 SLSLFGC-TNIFYEEENPGGCEDEYLVNPTCQVLVKDFT----------FEGFSRLRFLN 181
L+ ++ + G C + + + Q L+ D T F + LR L+
Sbjct: 129 ELNATAVHADLPVPDIISGLCSNRW-IQQNLQCLLLDSTSIPQNSRLLFFSQLTGLRILS 187
Query: 182 LGRMIDWVPVESLLRPLNSLAALDLSGIQTSDAAFLTQWKDSLVSLVLYNMDL----SDD 237
+ + + + L L +LD+S +D + L KD L SL ++ +
Sbjct: 188 VFNVCFHTEDLANVSQLPRLESLDISNTLVTDISALLTCKDRLKSLTMHYLKCLAMTKSQ 247
Query: 238 HIRVIVQLHKLRHLDISRDR-LSSYYKFKLTREVLSLFVQKLGNLMSLDISGHMILENCS 296
+ VI +L L HLDIS R L S F L ++ L N++SLDISG NC
Sbjct: 248 ILAVIRELKCLLHLDISDHRQLKSDLAFHLLQQK-----DILPNVVSLDISGG----NC- 297
Query: 297 ISKMEEEAGQTSIEPSKSSIIPFRALKRPLQFLGLFEN---SLCRLTHIPAYKVSGDKNE 353
+ +EA + I L+ +QF+GL S T +V+G +
Sbjct: 298 ---ITDEAVELFIR-----------LRPAMQFVGLLATDAGSSDFFTTKQGLRVAGGASM 343
Query: 354 EQVLNAIEAYTEHRPEITSRAINLLFDIARIERCNQLLRALKLVITALKCHKYDRNIQVT 413
Q+ A+ Y +R A++ LF + LKLV ++ H D +Q T
Sbjct: 344 SQISEALSRY-RNRSCFVKEALHRLFTETFSMEVT-MPAILKLVAIGMRNHPLDLRVQFT 401
Query: 414 GSAALFYLTNSEYRSEQSVKLRRQVIQVVLNGMESYQEVT-VQRNCCLTLCNFSIPEELE 472
SA LT V+L +V ++ ++++ +Q+NC L+L N I ++
Sbjct: 402 ASACALNLTRQGLAKGMPVRLLSEVTCLLFKALKNFPHYQQLQKNCLLSLTNSRILVDVP 461
Query: 473 FQYRRVNELLLSILNPTRQDESIQRIAVHLCNALVCQVDNDHKEAVGKMGFVVT-MLKLI 531
F + ++ L ++ +Q +AV + + L Q+ + + ++ V +L ++
Sbjct: 462 FDRFDAAKFVMRWLCK-HENPKMQTMAVSVTSILALQLSPEQTAQLEELFMAVKELLAIV 520
Query: 532 QKKLLDKTCDQVMEFSWSALWNITDETPDNCEMFLNFNGMKLFLDCLKEFPEKQELHRNM 591
++K + D F+ ALWN+TD +P C+ F+ G+++F+ L+ F E + +
Sbjct: 521 KQKTTENLDDVTFLFTLKALWNLTDGSPAACKHFIENQGLQIFIQVLETFSE-SAIQSKV 579
Query: 592 LGLLGNVAEVKELRPQLMTSQFISVFSNLLESKADGIEVSYNACGVLSHIMFDGPEAWGV 651
LGLL N+AEV+EL +L+T + ++LL S+ +EVSY A G+++H+ D + W
Sbjct: 580 LGLLNNIAEVRELSSKLVTEDVLKHINSLLCSRE--MEVSYFAAGIIAHLTSD-RQLWIS 636
Query: 652 CEPQREEVEERMWAAIQSWDINSRRN---INYRSFEPILRLLPQGISPVSQHWATWALYN 708
+ QR + + + A IQ+W +S + + YRSF+ LL P Q WA WA+Y+
Sbjct: 637 RDFQRRTLLQDLHATIQNWPSSSCKMTALVTYRSFKTFFPLLGNFSQPEVQLWALWAMYH 696
Query: 709 LVS 711
+ S
Sbjct: 697 VCS 699
>gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2
[Homo sapiens]
Length = 690
Score = 37.7 bits (86), Expect = 0.040
Identities = 46/203 (22%), Positives = 87/203 (42%), Gaps = 17/203 (8%)
Query: 92 VQDQDLEAIRKQ--DLVELYLTNCEKLSAKSLQTLRSFSHTLVSLSLFGCTNIFYEEENP 149
V D + I K +L +Y+ +C+ ++ SL++L V L+L C I
Sbjct: 413 VTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLSPLKQLTV-LNLANCVRI------- 464
Query: 150 GGCEDEYLVNPTCQVLVKDFTFEGFSRLRFLNLGRMIDWVPVESLLRPLNSLAALDLSGI 209
G + ++ + +++ RL ++ ++ + P + L L + L GI
Sbjct: 465 GDMGLKQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPNLNYLS-LRNCEHLTAQGI 523
Query: 210 QTSDAAFLTQWKDSLVSLVLYNMDLSDDHIRVIVQLHKLRHLDISRDRLSSYYKFKLTRE 269
F SLVS+ L D+S++ + V+ + KL+ L +S + ++T
Sbjct: 524 GYIVNIF------SLVSIDLSGTDISNEGLNVLSRHKKLKELSVSECYRITDDGIQITDS 577
Query: 270 VLSLFVQKLGNLMSLDISGHMIL 292
+ + K L LDISG ++L
Sbjct: 578 AMEMLSAKCHYLHILDISGCVLL 600
>gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo
sapiens]
Length = 424
Score = 37.0 bits (84), Expect = 0.069
Identities = 65/253 (25%), Positives = 103/253 (40%), Gaps = 60/253 (23%)
Query: 22 DGTLGYLLDKETLRLHPDIFLPSEICDRLVNEYVELVNAACNF--EPHESFFSLFSDPRS 79
D +L LD LHPD+ RL+++ V +F +P FS F
Sbjct: 133 DESLWQTLDLTGKNLHPDV------TGRLLSQGVIAFRCPRSFMDQPLAEHFSPF----- 181
Query: 80 TRLTRIHLREDLVQDQDLEAIRKQDLVELYLTNCEKLSAKSLQTLR---------SFSHT 130
R+ + L +++ L I L+ C KL SL+ LR + +
Sbjct: 182 -RVQHMDLSNSVIEVSTLHGI---------LSQCSKLQNLSLEGLRLSDPIVNTLAKNSN 231
Query: 131 LVSLSLFGCTNIFYEEENPGGCEDEYLVNPTCQVLVKDFTFEGFSRLRFLNLGRMIDWVP 190
LV L+L GC+ E+ + Q L+ SRL LNL D+
Sbjct: 232 LVRLNLSGCSGF-----------SEFAL----QTLLSSC-----SRLDELNLSWCFDFTE 271
Query: 191 VE---SLLRPLNSLAALDLSG----IQTSDAAFLTQWKDSLVSLVLYN-MDLSDDHIRVI 242
++ ++ L+LSG +Q SD + L + +LV L L + + L +D +
Sbjct: 272 KHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEF 331
Query: 243 VQLHKLRHLDISR 255
QL+ L+HL +SR
Sbjct: 332 FQLNYLQHLSLSR 344
Score = 33.5 bits (75), Expect = 0.76
Identities = 34/125 (27%), Positives = 61/125 (48%), Gaps = 10/125 (8%)
Query: 175 SRLRFLNLGRMIDWVPVESLLRPLNSLAALDLSGIQTSDAAFLTQWKDSLVSLVLYNM-- 232
S+L+ L+L + P+ + L ++L L+LSG L S L N+
Sbjct: 206 SKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSW 265
Query: 233 --DLSDDHIRVIVQLHKLRHLDISRDRLS-SYYKFKLTREVLSLFVQKLGNLMSLDISGH 289
D ++ H++V V H+ + +L+ S Y+ L + LS V++ NL+ LD+S
Sbjct: 266 CFDFTEKHVQVAVA-----HVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDS 320
Query: 290 MILEN 294
++L+N
Sbjct: 321 VMLKN 325
>gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo
sapiens]
Length = 410
Score = 37.0 bits (84), Expect = 0.069
Identities = 65/253 (25%), Positives = 103/253 (40%), Gaps = 60/253 (23%)
Query: 22 DGTLGYLLDKETLRLHPDIFLPSEICDRLVNEYVELVNAACNF--EPHESFFSLFSDPRS 79
D +L LD LHPD+ RL+++ V +F +P FS F
Sbjct: 133 DESLWQTLDLTGKNLHPDV------TGRLLSQGVIAFRCPRSFMDQPLAEHFSPF----- 181
Query: 80 TRLTRIHLREDLVQDQDLEAIRKQDLVELYLTNCEKLSAKSLQTLR---------SFSHT 130
R+ + L +++ L I L+ C KL SL+ LR + +
Sbjct: 182 -RVQHMDLSNSVIEVSTLHGI---------LSQCSKLQNLSLEGLRLSDPIVNTLAKNSN 231
Query: 131 LVSLSLFGCTNIFYEEENPGGCEDEYLVNPTCQVLVKDFTFEGFSRLRFLNLGRMIDWVP 190
LV L+L GC+ E+ + Q L+ SRL LNL D+
Sbjct: 232 LVRLNLSGCSGF-----------SEFAL----QTLLSSC-----SRLDELNLSWCFDFTE 271
Query: 191 VE---SLLRPLNSLAALDLSG----IQTSDAAFLTQWKDSLVSLVLYN-MDLSDDHIRVI 242
++ ++ L+LSG +Q SD + L + +LV L L + + L +D +
Sbjct: 272 KHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEF 331
Query: 243 VQLHKLRHLDISR 255
QL+ L+HL +SR
Sbjct: 332 FQLNYLQHLSLSR 344
Score = 33.5 bits (75), Expect = 0.76
Identities = 34/125 (27%), Positives = 61/125 (48%), Gaps = 10/125 (8%)
Query: 175 SRLRFLNLGRMIDWVPVESLLRPLNSLAALDLSGIQTSDAAFLTQWKDSLVSLVLYNM-- 232
S+L+ L+L + P+ + L ++L L+LSG L S L N+
Sbjct: 206 SKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSW 265
Query: 233 --DLSDDHIRVIVQLHKLRHLDISRDRLS-SYYKFKLTREVLSLFVQKLGNLMSLDISGH 289
D ++ H++V V H+ + +L+ S Y+ L + LS V++ NL+ LD+S
Sbjct: 266 CFDFTEKHVQVAVA-----HVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDS 320
Query: 290 MILEN 294
++L+N
Sbjct: 321 VMLKN 325
>gi|66472382 nischarin [Homo sapiens]
Length = 1504
Score = 35.0 bits (79), Expect = 0.26
Identities = 32/116 (27%), Positives = 57/116 (49%), Gaps = 22/116 (18%)
Query: 190 PVESLLRPLNSLAALDLSGIQTSDAAFLTQWKDSLVSLV--LYNMDLSDDHIRVI---VQ 244
PV +++ +L LDLS S+ D V L+ + +DLS + + V+
Sbjct: 278 PVTAVIPTWQALTTLDLSHNSISEI-------DESVKLIPKIEFLDLSHNGLLVVDNLQH 330
Query: 245 LHKLRHLDISRDRLSSYYKFKLTREVLSLFVQKLGNLMSLDISGHMILENCSISKM 300
L+ L HLD+S ++LSS L KLGN+ +L+++G+++ + K+
Sbjct: 331 LYNLVHLDLSYNKLSS----------LEGLHTKLGNIKTLNLAGNLLESLSGLHKL 376
>gi|15529984 armadillo repeat containing 6 [Homo sapiens]
Length = 476
Score = 33.9 bits (76), Expect = 0.58
Identities = 26/110 (23%), Positives = 48/110 (43%), Gaps = 4/110 (3%)
Query: 490 RQDESIQRIAVHLCNALVCQVDNDH-KEAVGKMGFVVTMLKLIQKKLLDKTCDQVMEFSW 548
R +Q + + + L ND K+A+ + G +++ + + L T QV E S
Sbjct: 310 RDQSGVQELVKQVLSTLRAIAGNDDVKDAIVRAGGTESIVAAMTQHL---TSPQVCEQSC 366
Query: 549 SALWNITDETPDNCEMFLNFNGMKLFLDCLKEFPEKQELHRNMLGLLGNV 598
+AL + PDN + + G L +K P+K + + L+ N+
Sbjct: 367 AALCFLALRKPDNSRIIVEGGGAVAALQAMKAHPQKAGVQKQACMLIRNL 416
>gi|224500884 hypothetical protein LOC339541 [Homo sapiens]
Length = 440
Score = 33.5 bits (75), Expect = 0.76
Identities = 25/108 (23%), Positives = 54/108 (50%), Gaps = 3/108 (2%)
Query: 389 QLLRALKLVITALKCHKY-DRNIQVTGSAALFYLTNSEYRSEQSVKLRRQVIQVVLNGME 447
+LLR++ + ++A+ ++Y ++V G L + E E++ K +++QV+ N
Sbjct: 78 KLLRSIGIFLSAVSSNRYLIEFLEVGGVLTLLEILGLEKIKEEAKKESVKLLQVIANSGR 137
Query: 448 SYQEVTVQRNCCLTLCNFSIPEELEFQYRRVNELLLSIL--NPTRQDE 493
+Y+E+ + ++ F + E V LL S++ NP Q++
Sbjct: 138 TYKELICESYGVRSIAEFLAKSKSEETQEEVQVLLDSLVHGNPKYQNQ 185
>gi|7662320 leucine-rich repeats and immunoglobulin-like domains 2
[Homo sapiens]
Length = 1065
Score = 33.5 bits (75), Expect = 0.76
Identities = 29/116 (25%), Positives = 49/116 (42%), Gaps = 4/116 (3%)
Query: 171 FEGFSRLRFLNLGRMIDWVPVESLLRPLNSLAALDLSGIQTS----DAAFLTQWKDSLVS 226
F G S L LNLG + + R L++L LDL + S DA+ SL
Sbjct: 331 FVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTK 390
Query: 227 LVLYNMDLSDDHIRVIVQLHKLRHLDISRDRLSSYYKFKLTREVLSLFVQKLGNLM 282
L+L + + + L L HLD++ + + S + ++ L + +L+
Sbjct: 391 LILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFSQTHLKELILNTSSLL 446
>gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens]
Length = 3639
Score = 32.7 bits (73), Expect = 1.3
Identities = 48/222 (21%), Positives = 83/222 (37%), Gaps = 43/222 (19%)
Query: 499 AVHLCNALVCQVDNDHKEAVGKMGFVVTMLKLIQKKLLDK---------TCDQVMEFSWS 549
A+HLC H+ +G V +L+ + LL++ Q ++ +WS
Sbjct: 1731 ALHLCTKFA---KFQHQVEMGSQR--VAACRLLAESLLERGHSAGPMVRQRQQDLQTAWS 1785
Query: 550 ALWNITDETPDNCEMFLNFNGMKLFLDCLKEFPEKQELHRNMLGLLGNVAEVKELRPQLM 609
LW +T L++ +HR++L +L V E P +
Sbjct: 1786 ELWELTQARGH----------------ALRDTETTLRVHRDLLEVLTQVQEKATSLPNNV 1829
Query: 610 TSQFISVFSNL-----LESKADGIEVSYNACGVLSHIMFDGPEAWGVCE-PQREEVEERM 663
+ + L LE + G E L ++ +C PQ V++R
Sbjct: 1830 ARDLCGLEAQLRSHQGLERELVGTERQ------LQELLETAGRVQKLCPGPQAHAVQQRQ 1883
Query: 664 WAAIQSWDINSRRNINYRSFEPILRLLPQGISPVSQHWATWA 705
A Q+W + RR R+ RLL + + V + +A+WA
Sbjct: 1884 QAVTQAWAVLQRRMEQRRAQLERARLLARFRTAV-RDYASWA 1924
>gi|21327710 nucleosome assembly protein 1-like 3 [Homo sapiens]
Length = 506
Score = 32.3 bits (72), Expect = 1.7
Identities = 13/33 (39%), Positives = 20/33 (60%)
Query: 66 PHESFFSLFSDPRSTRLTRIHLREDLVQDQDLE 98
P+ SFF+ FS P + ++ RED + D+D E
Sbjct: 435 PNASFFNFFSPPEIPMIGKLEPREDAILDEDFE 467
>gi|99028953 inscuteable isoform a [Homo sapiens]
Length = 579
Score = 32.3 bits (72), Expect = 1.7
Identities = 39/184 (21%), Positives = 77/184 (41%), Gaps = 13/184 (7%)
Query: 461 TLCNFSIPEELEFQYRRVNELLL--SILNPTRQDESIQRIAVHLCNALVCQVDNDHKEAV 518
TL + EE Q +V+ +L IL E+ + A A+V QV + H
Sbjct: 304 TLASICCVEEGVHQLEKVDGVLCLADILTDNSHSEATRAEAA----AVVAQVTSPHLPVT 359
Query: 519 GKMG-FVVTMLKLIQ---KKLLDKTCDQVMEFSWSALWNITDETPDNCEMFLNFNGMKLF 574
+ F+ +M +++ K + + +V + +AL NIT CEM L N +++
Sbjct: 360 QHLSSFLESMEEIVTALVKLCQEASSGEVFLLASAALANITFFDTMACEMLLQLNAIRVL 419
Query: 575 LDCL--KEFPEKQELHRNMLGLLGNVAEVKELRPQLMTSQFISVFSNLLESK-ADGIEVS 631
L+ K+ + ++ +L N++ +++ ++ + + +L K G
Sbjct: 420 LEACSDKQRVDTPYTRDQIVTILANMSVLEQCASDIIQENGVQLIMGMLSEKPRSGTPAE 479
Query: 632 YNAC 635
AC
Sbjct: 480 VAAC 483
>gi|110227584 inscuteable isoform b [Homo sapiens]
Length = 532
Score = 32.3 bits (72), Expect = 1.7
Identities = 39/184 (21%), Positives = 77/184 (41%), Gaps = 13/184 (7%)
Query: 461 TLCNFSIPEELEFQYRRVNELLL--SILNPTRQDESIQRIAVHLCNALVCQVDNDHKEAV 518
TL + EE Q +V+ +L IL E+ + A A+V QV + H
Sbjct: 257 TLASICCVEEGVHQLEKVDGVLCLADILTDNSHSEATRAEAA----AVVAQVTSPHLPVT 312
Query: 519 GKMG-FVVTMLKLIQ---KKLLDKTCDQVMEFSWSALWNITDETPDNCEMFLNFNGMKLF 574
+ F+ +M +++ K + + +V + +AL NIT CEM L N +++
Sbjct: 313 QHLSSFLESMEEIVTALVKLCQEASSGEVFLLASAALANITFFDTMACEMLLQLNAIRVL 372
Query: 575 LDCL--KEFPEKQELHRNMLGLLGNVAEVKELRPQLMTSQFISVFSNLLESK-ADGIEVS 631
L+ K+ + ++ +L N++ +++ ++ + + +L K G
Sbjct: 373 LEACSDKQRVDTPYTRDQIVTILANMSVLEQCASDIIQENGVQLIMGMLSEKPRSGTPAE 432
Query: 632 YNAC 635
AC
Sbjct: 433 VAAC 436
>gi|53729344 plakophilin 1 isoform 1a [Homo sapiens]
Length = 726
Score = 32.0 bits (71), Expect = 2.2
Identities = 36/164 (21%), Positives = 68/164 (41%), Gaps = 20/164 (12%)
Query: 491 QDESIQRIAVHLCNALVCQVDNDHKEAVGKMGFVVTMLKLIQKKLLDKTCDQVMEFSWSA 550
QDE Q I + C D K+ V ++G + ++ L++ V + + A
Sbjct: 257 QDEKYQAIGAYYIQH-TCFQDESAKQQVYQLGGICKLVDLLRSPN-----QNVQQAAAGA 310
Query: 551 LWNITDETPDNCEMFLNFNGMKLFLDCLKEFPEKQELHRNMLGLLGNVAEVKELRPQL-- 608
L N+ + N NG++ + L+ E+ + + GLL N++ EL+ +L
Sbjct: 311 LRNLVFRSTTNKLETRRQNGIREAVSLLRR-TGNAEIQKQLTGLLWNLSSTDELKEELIA 369
Query: 609 -----MTSQFISVFSNLLESKAD------GIEVSYNACGVLSHI 641
+ + I FS + ++ EV +NA G L ++
Sbjct: 370 DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRNL 413
>gi|169218113 PREDICTED: similar to plakophilin 1, partial [Homo
sapiens]
Length = 625
Score = 32.0 bits (71), Expect = 2.2
Identities = 36/164 (21%), Positives = 68/164 (41%), Gaps = 20/164 (12%)
Query: 491 QDESIQRIAVHLCNALVCQVDNDHKEAVGKMGFVVTMLKLIQKKLLDKTCDQVMEFSWSA 550
QDE Q I + C D K+ V ++G + ++ L++ V + + A
Sbjct: 156 QDEKYQAIGAYYIQH-TCFQDESAKQQVYQLGGICKLVDLLRSPN-----QNVQQAAAGA 209
Query: 551 LWNITDETPDNCEMFLNFNGMKLFLDCLKEFPEKQELHRNMLGLLGNVAEVKELRPQL-- 608
L N+ + N NG++ + L+ E+ + + GLL N++ EL+ +L
Sbjct: 210 LRNLVFRSTTNKLETRRQNGIREAVSLLRR-TGNAEIQKQLTGLLWNLSSTDELKEELIA 268
Query: 609 -----MTSQFISVFSNLLESKAD------GIEVSYNACGVLSHI 641
+ + I FS + ++ EV +NA G L ++
Sbjct: 269 DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRNL 312
>gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1
[Homo sapiens]
Length = 735
Score = 32.0 bits (71), Expect = 2.2
Identities = 43/198 (21%), Positives = 84/198 (42%), Gaps = 24/198 (12%)
Query: 92 VQDQDLEAIRKQ--DLVELYLTNCEKLSAKSLQTLRSFSHTLVSLSLFGCTNIFYEEENP 149
V D + I K +L +Y+ +C+ ++ SL++L V L+L C I
Sbjct: 413 VTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLSPLKQLTV-LNLANCVRI------- 464
Query: 150 GGCEDEYLVNPTCQVLVKDFTFEGFSRLRFLNLGRMIDWVPVESLLRPLNSLAALDLSGI 209
G + ++ + +++ RL ++ ++ + P + L L + L GI
Sbjct: 465 GDMGLKQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPNLNYLS-LRNCEHLTAQGI 523
Query: 210 QTSDAAFLTQWKDSLVSLVLYNMDLSDDHIRVIVQLHKLRHLDISRDRLSSYYKFKLTRE 269
F SLVS+ L D+S++ + V+ + KL+ L +S +++T +
Sbjct: 524 GYIVNIF------SLVSIDLSGTDISNEGLNVLSRHKKLKELSVSE-------CYRITDD 570
Query: 270 VLSLFVQKLGNLMSLDIS 287
+ F + L LD+S
Sbjct: 571 GIQAFCKSSLILEHLDVS 588
>gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]
Length = 423
Score = 32.0 bits (71), Expect = 2.2
Identities = 17/55 (30%), Positives = 32/55 (58%), Gaps = 2/55 (3%)
Query: 90 DLVQDQDLEAIRK--QDLVELYLTNCEKLSAKSLQTLRSFSHTLVSLSLFGCTNI 142
D + +EA+ + + L L L C +L ++L+ ++++ H LVSL+L C+ I
Sbjct: 167 DQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRI 221
>gi|122937470 carboxypeptidase N, polypeptide 2, 83kD [Homo sapiens]
Length = 545
Score = 31.6 bits (70), Expect = 2.9
Identities = 37/122 (30%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
Query: 171 FEGFSRLRFLNLGRMIDWVPVESLLRPLNSLAALDLSGIQTSDAAFLTQWK-DSLVSLVL 229
F+ + L+ LNL + + E L PL SL L LS S K SL L L
Sbjct: 165 FQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFL 224
Query: 230 YNMDLSDDHIRVIVQLHKLRHLDISRDRLSSYYKFKLTREVLSLFVQKLGNLMSLDISGH 289
+ ++S+ +V QL L L + R+ +T LS+F LGNL L + +
Sbjct: 225 DSNNISELPPQVFSQLFCLERLWLQRN--------AITHLPLSIFA-SLGNLTFLSLQWN 275
Query: 290 MI 291
M+
Sbjct: 276 ML 277
>gi|53729346 plakophilin 1 isoform 1b [Homo sapiens]
Length = 747
Score = 31.2 bits (69), Expect = 3.8
Identities = 36/161 (22%), Positives = 66/161 (40%), Gaps = 20/161 (12%)
Query: 491 QDESIQRIAVHLCNALVCQVDNDHKEAVGKMGFVVTMLKLIQKKLLDKTCDQVMEFSWSA 550
QDE Q I + C D K+ V ++G + ++ L++ V + + A
Sbjct: 257 QDEKYQAIGAYYIQH-TCFQDESAKQQVYQLGGICKLVDLLRSPN-----QNVQQAAAGA 310
Query: 551 LWNITDETPDNCEMFLNFNGMKLFLDCLKEFPEKQELHRNMLGLLGNVAEVKELRPQL-- 608
L N+ + N NG++ + L+ E+ + + GLL N++ EL+ +L
Sbjct: 311 LRNLVFRSTTNKLETRRQNGIREAVSLLRR-TGNAEIQKQLTGLLWNLSSTDELKEELIA 369
Query: 609 -----MTSQFISVFSNLLESKAD------GIEVSYNACGVL 638
+ + I FS + ++ EV +NA G L
Sbjct: 370 DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCL 410
>gi|76880480 hypothetical protein LOC9865 [Homo sapiens]
Length = 811
Score = 31.2 bits (69), Expect = 3.8
Identities = 21/43 (48%), Positives = 26/43 (60%), Gaps = 2/43 (4%)
Query: 171 FEGFSRLRFLNL-GRMIDWVPVESLLRPLNSLAALDLSGIQTS 212
F G LR L L G + +P +LL PL+SL ALDLSG + S
Sbjct: 273 FWGLEALRELRLEGNRLSQLPT-ALLEPLHSLEALDLSGNELS 314
>gi|194294510 kinesin family member C3 isoform 2 [Homo sapiens]
Length = 826
Score = 30.8 bits (68), Expect = 4.9
Identities = 58/265 (21%), Positives = 115/265 (43%), Gaps = 33/265 (12%)
Query: 360 IEAYTEHRPEITSRAINLLFDIARIE-RCNQLLRALKLVITALKCH----KYD-RNIQVT 413
++ T+ E+ R + L + A+ E R ++ LR I +L+ KY + ++V
Sbjct: 205 VQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVE 264
Query: 414 GSAALFYLTNSEYRSE---QSVKLRRQVIQVVLNGMESYQEVTVQRNCCLTLCNFSIPEE 470
S L+ S+ R++ + V ++RQV++ + ++S ++T + + + E
Sbjct: 265 SSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYE----SE 320
Query: 471 LEFQYRRVNELLLSILNPTRQDESIQRIAVHLCNALVCQVDNDHKEAVGKMGFVVTMLKL 530
LE + ++ E + S+ +++ + I A V ++ H+ G V T L
Sbjct: 321 LERAHGQMLEEMQSL-----EEDKNRAIEEAFARAQV-EMKAVHENLAG----VRTNLLT 370
Query: 531 IQKKLLDKTCD------QVMEFSW---SALWNITDETPDNCEMFLNFNGMKLFLDCLKEF 581
+Q L T D QV F AL ++ E E +N N +L +E
Sbjct: 371 LQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEE-VNSNNQELLRKYRREL 429
Query: 582 PEKQELHRNMLGLLGNVAEVKELRP 606
+++ H ++ L GN+ + +RP
Sbjct: 430 QLRKKCHNELVRLKGNIRVIARVRP 454
>gi|194294508 kinesin family member C3 isoform 3 [Homo sapiens]
Length = 687
Score = 30.8 bits (68), Expect = 4.9
Identities = 58/265 (21%), Positives = 115/265 (43%), Gaps = 33/265 (12%)
Query: 360 IEAYTEHRPEITSRAINLLFDIARIE-RCNQLLRALKLVITALKCH----KYD-RNIQVT 413
++ T+ E+ R + L + A+ E R ++ LR I +L+ KY + ++V
Sbjct: 66 VQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVE 125
Query: 414 GSAALFYLTNSEYRSE---QSVKLRRQVIQVVLNGMESYQEVTVQRNCCLTLCNFSIPEE 470
S L+ S+ R++ + V ++RQV++ + ++S ++T + + + E
Sbjct: 126 SSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYE----SE 181
Query: 471 LEFQYRRVNELLLSILNPTRQDESIQRIAVHLCNALVCQVDNDHKEAVGKMGFVVTMLKL 530
LE + ++ E + S+ +++ + I A V ++ H+ G V T L
Sbjct: 182 LERAHGQMLEEMQSL-----EEDKNRAIEEAFARAQV-EMKAVHENLAG----VRTNLLT 231
Query: 531 IQKKLLDKTCD------QVMEFSW---SALWNITDETPDNCEMFLNFNGMKLFLDCLKEF 581
+Q L T D QV F AL ++ E E +N N +L +E
Sbjct: 232 LQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEE-VNSNNQELLRKYRREL 290
Query: 582 PEKQELHRNMLGLLGNVAEVKELRP 606
+++ H ++ L GN+ + +RP
Sbjct: 291 QLRKKCHNELVRLKGNIRVIARVRP 315
>gi|94536858 kinesin family member C3 isoform 1 [Homo sapiens]
Length = 833
Score = 30.8 bits (68), Expect = 4.9
Identities = 58/265 (21%), Positives = 115/265 (43%), Gaps = 33/265 (12%)
Query: 360 IEAYTEHRPEITSRAINLLFDIARIE-RCNQLLRALKLVITALKCH----KYD-RNIQVT 413
++ T+ E+ R + L + A+ E R ++ LR I +L+ KY + ++V
Sbjct: 205 VQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVE 264
Query: 414 GSAALFYLTNSEYRSE---QSVKLRRQVIQVVLNGMESYQEVTVQRNCCLTLCNFSIPEE 470
S L+ S+ R++ + V ++RQV++ + ++S ++T + + + E
Sbjct: 265 SSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYE----SE 320
Query: 471 LEFQYRRVNELLLSILNPTRQDESIQRIAVHLCNALVCQVDNDHKEAVGKMGFVVTMLKL 530
LE + ++ E + S+ +++ + I A V ++ H+ G V T L
Sbjct: 321 LERAHGQMLEEMQSL-----EEDKNRAIEEAFARAQV-EMKAVHENLAG----VRTNLLT 370
Query: 531 IQKKLLDKTCD------QVMEFSW---SALWNITDETPDNCEMFLNFNGMKLFLDCLKEF 581
+Q L T D QV F AL ++ E E +N N +L +E
Sbjct: 371 LQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEE-VNSNNQELLRKYRREL 429
Query: 582 PEKQELHRNMLGLLGNVAEVKELRP 606
+++ H ++ L GN+ + +RP
Sbjct: 430 QLRKKCHNELVRLKGNIRVIARVRP 454
>gi|4826952 proteasome 26S non-ATPase subunit 5 [Homo sapiens]
Length = 504
Score = 30.8 bits (68), Expect = 4.9
Identities = 24/88 (27%), Positives = 46/88 (52%), Gaps = 5/88 (5%)
Query: 370 ITSRAINLLFDIARIERCNQLLRALKLVITALKCHKYDRNIQVTGSAALFYLTNSEYRSE 429
+ ++A+ LL ++AR+E + LRAL V+ A+ ++ + LF L N +R +
Sbjct: 1 MAAQALALLREVARLEAPLEELRALHSVLQAVPLNELRQQAAELRLGPLFSLLNENHREK 60
Query: 430 QSVKLRRQVIQVVLNGMESYQEVTVQRN 457
++ + +++ +L ME V V RN
Sbjct: 61 TTLCV--SILERLLQAME---PVHVARN 83
>gi|21071028 acidic nuclear phosphoprotein 32D [Homo sapiens]
Length = 131
Score = 30.8 bits (68), Expect = 4.9
Identities = 30/125 (24%), Positives = 60/125 (48%), Gaps = 13/125 (10%)
Query: 188 WVPVESLLRPLNSLAALDLSGIQTSDAAF--LTQWKDSLVSLVLYNMDLSDDHIRVIVQL 245
W+ +E R + + L L Q+++ LT + L L N+ L+ I + +L
Sbjct: 6 WIHLELRNRTPSDVKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTS--IANLPKL 63
Query: 246 HKLRHLDISRDRLSSYYKFKLTREVLSLFVQKLGNLMSLDISGHMILENCSISKMEEEAG 305
+KL+ L++S +R S L + +K NL+ L++SG+ I + +I +++
Sbjct: 64 NKLKKLELSSNRASVG---------LEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLEN 114
Query: 306 QTSIE 310
S++
Sbjct: 115 LESLD 119
>gi|189011568 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 30.4 bits (67), Expect = 6.4
Identities = 33/164 (20%), Positives = 71/164 (43%), Gaps = 13/164 (7%)
Query: 491 QDESIQRIAVHLCNALVCQVDNDHKEAVGKMGFVVTMLKLIQKKLLDKTCDQVMEFSWSA 550
+ E +Q++ + L + D + K+ + ++G V +++ + + T V+ SA
Sbjct: 536 ESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVL----SA 591
Query: 551 LWNITDETPDNCEMFLNFNGMKLFLDCLKEFPEKQE---LHRNMLGLLGNVAEV---KEL 604
LWN++ +N +G FL + + + + G+L NV+ + E
Sbjct: 592 LWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNED 651
Query: 605 RPQLMTSQFISVFSNLLES-KADGIEVSYNACGVLSHIMFDGPE 647
Q++ + LL+ K+ + + NACG L ++ P+
Sbjct: 652 HRQILREN--NCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPK 693
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,469,804
Number of Sequences: 37866
Number of extensions: 1163167
Number of successful extensions: 2698
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 2636
Number of HSP's gapped (non-prelim): 60
length of query: 766
length of database: 18,247,518
effective HSP length: 110
effective length of query: 656
effective length of database: 14,082,258
effective search space: 9237961248
effective search space used: 9237961248
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.