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Search of human proteins with 33383235
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33383235 minichromosome maintenance complex component 10
isoform 2 [Homo sapiens]
(874 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33383235 minichromosome maintenance complex component 10 isof... 1738 0.0
gi|33383237 minichromosome maintenance complex component 10 isof... 1733 0.0
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 47 1e-04
gi|186659512 calmodulin regulated spectrin-associated protein 1 ... 44 5e-04
gi|7662340 MORC family CW-type zinc finger 2 [Homo sapiens] 44 5e-04
gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens] 44 7e-04
gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens] 44 7e-04
gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens] 44 7e-04
gi|217330641 IWS1 homolog [Homo sapiens] 44 7e-04
gi|112789538 troponin T3, skeletal, fast isoform 2 [Homo sapiens] 43 0.001
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s... 43 0.001
gi|164419758 bromodomain containing 2 [Homo sapiens] 43 0.001
gi|4826806 bromodomain containing 2 [Homo sapiens] 43 0.001
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 43 0.001
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 43 0.001
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 43 0.001
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 43 0.001
gi|187173290 troponin T1, skeletal, slow isoform b [Homo sapiens] 42 0.002
gi|187173288 troponin T1, skeletal, slow isoform a [Homo sapiens] 42 0.002
gi|209862789 microtubule associated monoxygenase, calponin and L... 42 0.002
gi|58535453 CDK5 regulatory subunit associated protein 2 isoform... 42 0.002
gi|58535451 CDK5 regulatory subunit associated protein 2 isoform... 42 0.002
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 42 0.002
gi|16445033 ACRC protein [Homo sapiens] 42 0.002
gi|21735548 centrosomal protein 2 [Homo sapiens] 42 0.003
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 42 0.003
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 41 0.004
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 41 0.004
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 41 0.004
gi|156104891 general transcription factor IIF, polypeptide 1, 74... 40 0.007
>gi|33383235 minichromosome maintenance complex component 10 isoform
2 [Homo sapiens]
Length = 874
Score = 1738 bits (4501), Expect = 0.0
Identities = 874/874 (100%), Positives = 874/874 (100%)
Query: 1 MDEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEAD 60
MDEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEAD
Sbjct: 1 MDEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEAD 60
Query: 61 DGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELR 120
DGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELR
Sbjct: 61 DGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELR 120
Query: 121 NLQEQMKALQEQLKVTTIKQTASPARLQKSPEKSPRPPLKERRVQRIQESTCFSAELDVP 180
NLQEQMKALQEQLKVTTIKQTASPARLQKSPEKSPRPPLKERRVQRIQESTCFSAELDVP
Sbjct: 121 NLQEQMKALQEQLKVTTIKQTASPARLQKSPEKSPRPPLKERRVQRIQESTCFSAELDVP 180
Query: 181 ALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQIVGTPGSSGET 240
ALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQIVGTPGSSGET
Sbjct: 181 ALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQIVGTPGSSGET 240
Query: 241 TQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAREKLEEIDWVTFGVIL 300
TQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAREKLEEIDWVTFGVIL
Sbjct: 241 TQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAREKLEEIDWVTFGVIL 300
Query: 301 KKVTPQSVNSGKTFSIWKLNDLRDLTQCVSLFLFGEVHKALWKTEQGTVVGILNANPMKP 360
KKVTPQSVNSGKTFSIWKLNDLRDLTQCVSLFLFGEVHKALWKTEQGTVVGILNANPMKP
Sbjct: 301 KKVTPQSVNSGKTFSIWKLNDLRDLTQCVSLFLFGEVHKALWKTEQGTVVGILNANPMKP 360
Query: 361 KDGSEEVCLSIDHPQKVLIMGEALDLGTCKAKKKNGEPCTQTVNLRDCEYCQYHVQAQYK 420
KDGSEEVCLSIDHPQKVLIMGEALDLGTCKAKKKNGEPCTQTVNLRDCEYCQYHVQAQYK
Sbjct: 361 KDGSEEVCLSIDHPQKVLIMGEALDLGTCKAKKKNGEPCTQTVNLRDCEYCQYHVQAQYK 420
Query: 421 KLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVSSASYAASIAAAVAPKK 480
KLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVSSASYAASIAAAVAPKK
Sbjct: 421 KLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVSSASYAASIAAAVAPKK 480
Query: 481 KIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKAT 540
KIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKAT
Sbjct: 481 KIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKAT 540
Query: 541 ASGIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSSR 600
ASGIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSSR
Sbjct: 541 ASGIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSSR 600
Query: 601 QPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKLA 660
QPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKLA
Sbjct: 601 QPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKLA 660
Query: 661 AITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRRE 720
AITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRRE
Sbjct: 661 AITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRRE 720
Query: 721 QLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRVV 780
QLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRVV
Sbjct: 721 QLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRVV 780
Query: 781 TCKTCAYTHFKLLETCVSEQHEYHWHDGVKRFFKCPCGNRSISLDRLPNKHCSNCGLYKW 840
TCKTCAYTHFKLLETCVSEQHEYHWHDGVKRFFKCPCGNRSISLDRLPNKHCSNCGLYKW
Sbjct: 781 TCKTCAYTHFKLLETCVSEQHEYHWHDGVKRFFKCPCGNRSISLDRLPNKHCSNCGLYKW 840
Query: 841 ERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK 874
ERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK
Sbjct: 841 ERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK 874
>gi|33383237 minichromosome maintenance complex component 10 isoform
1 [Homo sapiens]
Length = 875
Score = 1733 bits (4489), Expect = 0.0
Identities = 874/875 (99%), Positives = 874/875 (99%), Gaps = 1/875 (0%)
Query: 1 MDEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEAD 60
MDEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEAD
Sbjct: 1 MDEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEAD 60
Query: 61 DGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELR 120
DGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELR
Sbjct: 61 DGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELR 120
Query: 121 NLQEQMKALQEQLKVTTIKQTASPARLQKSP-EKSPRPPLKERRVQRIQESTCFSAELDV 179
NLQEQMKALQEQLKVTTIKQTASPARLQKSP EKSPRPPLKERRVQRIQESTCFSAELDV
Sbjct: 121 NLQEQMKALQEQLKVTTIKQTASPARLQKSPVEKSPRPPLKERRVQRIQESTCFSAELDV 180
Query: 180 PALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQIVGTPGSSGE 239
PALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQIVGTPGSSGE
Sbjct: 181 PALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQIVGTPGSSGE 240
Query: 240 TTQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAREKLEEIDWVTFGVI 299
TTQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAREKLEEIDWVTFGVI
Sbjct: 241 TTQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAREKLEEIDWVTFGVI 300
Query: 300 LKKVTPQSVNSGKTFSIWKLNDLRDLTQCVSLFLFGEVHKALWKTEQGTVVGILNANPMK 359
LKKVTPQSVNSGKTFSIWKLNDLRDLTQCVSLFLFGEVHKALWKTEQGTVVGILNANPMK
Sbjct: 301 LKKVTPQSVNSGKTFSIWKLNDLRDLTQCVSLFLFGEVHKALWKTEQGTVVGILNANPMK 360
Query: 360 PKDGSEEVCLSIDHPQKVLIMGEALDLGTCKAKKKNGEPCTQTVNLRDCEYCQYHVQAQY 419
PKDGSEEVCLSIDHPQKVLIMGEALDLGTCKAKKKNGEPCTQTVNLRDCEYCQYHVQAQY
Sbjct: 361 PKDGSEEVCLSIDHPQKVLIMGEALDLGTCKAKKKNGEPCTQTVNLRDCEYCQYHVQAQY 420
Query: 420 KKLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVSSASYAASIAAAVAPK 479
KKLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVSSASYAASIAAAVAPK
Sbjct: 421 KKLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVSSASYAASIAAAVAPK 480
Query: 480 KKIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKA 539
KKIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKA
Sbjct: 481 KKIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKA 540
Query: 540 TASGIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSS 599
TASGIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSS
Sbjct: 541 TASGIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSS 600
Query: 600 RQPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKL 659
RQPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKL
Sbjct: 601 RQPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKL 660
Query: 660 AAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRR 719
AAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRR
Sbjct: 661 AAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRR 720
Query: 720 EQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRV 779
EQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRV
Sbjct: 721 EQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRV 780
Query: 780 VTCKTCAYTHFKLLETCVSEQHEYHWHDGVKRFFKCPCGNRSISLDRLPNKHCSNCGLYK 839
VTCKTCAYTHFKLLETCVSEQHEYHWHDGVKRFFKCPCGNRSISLDRLPNKHCSNCGLYK
Sbjct: 781 VTCKTCAYTHFKLLETCVSEQHEYHWHDGVKRFFKCPCGNRSISLDRLPNKHCSNCGLYK 840
Query: 840 WERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK 874
WERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK
Sbjct: 841 WERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK 875
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 46.6 bits (109), Expect = 1e-04
Identities = 61/229 (26%), Positives = 96/229 (41%), Gaps = 35/229 (15%)
Query: 544 IMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSSRQPP 603
I+ P IKS+ A+ K + E+ + S S + SP+ SS PP
Sbjct: 245 ILAVRPPQIKSLPATPQGKNMTPESEVLESFPEEDS----VLSHSSLSSPSSTSSPEGPP 300
Query: 604 AQPPRTGSEFPRLEGAPAT-MTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKLAAI 662
A P + S P P +T K +G E + KL + ++L
Sbjct: 301 APPKQHSSTSPFPTSTPLRRITKKFVKGSTE-------------KNKLRLQRDQERLGKQ 347
Query: 663 TKLRAKGQVLTKTNPNSIK-----KKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKK 717
KLRA+ + K + + KK+K+ + L+ KER EK + +DE E A K+
Sbjct: 348 LKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREK------REKDEKEKAEKQ 401
Query: 718 RREQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQME 766
R L +E Q+ L+AK + ++ E E + R E +K E+ E
Sbjct: 402 R---LKEERRKERQEALEAKLEEK---RKKEEEKRLREEEKRIKAEKAE 444
Score = 43.9 bits (102), Expect = 7e-04
Identities = 51/191 (26%), Positives = 84/191 (43%), Gaps = 28/191 (14%)
Query: 614 PRLEGAPAT-----MTPK--LGRGVLEGDDVLFYD-----------ESPPPRPK----LS 651
P+++ PAT MTP+ + E D VL + E PP PK S
Sbjct: 251 PQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTS 310
Query: 652 ALAEAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDEL 711
+ L ITK KG T+ N +++ Q+ L+++ E+ +A+
Sbjct: 311 PFPTSTPLRRITKKFVKGS--TEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAK 368
Query: 712 EPARKKRREQLAYLES---EEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEK 768
E A+KK+ E+ E E+ +K K K++ + +E E QE L +K + EE+
Sbjct: 369 EEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEE 428
Query: 769 MRNIREVKCRV 779
R +RE + R+
Sbjct: 429 KR-LREEEKRI 438
>gi|186659512 calmodulin regulated spectrin-associated protein 1 [Homo
sapiens]
Length = 1602
Score = 44.3 bits (103), Expect = 5e-04
Identities = 49/192 (25%), Positives = 81/192 (42%), Gaps = 21/192 (10%)
Query: 69 DEKENLATLFGDMEDLTDEEEVPA-------SQSTENRVLPAPAPRREKTNEELQEELRN 121
DE L +L G + +++ ++ P Q E+ + A K + EE R
Sbjct: 1245 DEDGELVSLDGSADLVSEGDQKPGVGFFFKDEQKAEDELAKKRAAFLLKQQRKA-EEARV 1303
Query: 122 LQEQMKALQEQLKVTTIKQTASPARLQKSPEKSPRPPLKE----RRVQRIQESTCFSAEL 177
++Q++A + +LK ++ A R++K EK+ R +K+ R+ Q+I E
Sbjct: 1304 RKQQLEA-EVELKRDEARRKAEEDRVRKEEEKARRELIKQEYLRRKQQQILEEQGLGKPK 1362
Query: 178 DVPALPRTKRVARTPKASPPDPKSSS-----SRMTSAPSQPLQTISRNKPSGITRGQIVG 232
P PR K V R S K SS SR S S L + + +P + G G
Sbjct: 1363 SKPKKPRPKSVHREESCSDSGTKCSSTPDNLSRTQSGSSLSLASAATTEPESVHSG---G 1419
Query: 233 TPGSSGETTQPI 244
TP E+ + +
Sbjct: 1420 TPSQRVESMEAL 1431
>gi|7662340 MORC family CW-type zinc finger 2 [Homo sapiens]
Length = 970
Score = 44.3 bits (103), Expect = 5e-04
Identities = 55/242 (22%), Positives = 99/242 (40%), Gaps = 41/242 (16%)
Query: 86 DEEEVPASQSTENRVLPAPAPRRE-KTNEELQ----EELRNLQEQMKALQEQ-------- 132
D E+ S + + +P R++ KT EE Q E++R QE+++ALQ+
Sbjct: 468 DPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQAD 527
Query: 133 -----LKVTTIKQTASPARLQKSPEKSP----------RPPL--KERRVQRIQESTCFSA 175
L+VTT T P R + P P RPP R + +++ S+
Sbjct: 528 LKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISS 587
Query: 176 ELDVPALPRTKRVARTPKASPPD-PKSSSSRMTSAPSQPLQTISRNKPS---------GI 225
+PAL + + + PP+ P+ ++ + S+P + + PS +
Sbjct: 588 TPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREV 647
Query: 226 TRGQIVGTPGSSGETTQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAR 285
+++ TP +T PI + + R R VS E ++ R+ R + + +
Sbjct: 648 PSPKVIKTPVVK-KTESPIKLSPATPSRKRSVAVSDEEEVEEEAERRKERCKRGRFVVKE 706
Query: 286 EK 287
EK
Sbjct: 707 EK 708
Score = 34.3 bits (77), Expect = 0.52
Identities = 46/227 (20%), Positives = 88/227 (38%), Gaps = 28/227 (12%)
Query: 565 KQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSSRQPPAQPPRTGSEFPRLEGAPA--- 621
K+ LE+ R S E R Q SP +P+ R P++PP + P + A
Sbjct: 529 KKLPLEVTTRPSTEEPVRRPQRP---RSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVI 585
Query: 622 TMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKLAAITKLRAKGQVLTKTNPNSIK 681
+ TPKL + PP P+ K + K ++ L + S+
Sbjct: 586 SSTPKLPALAAREEASTSRLLQPPEAPR-------KPANTLVKTASRPAPLVQQLSPSLL 638
Query: 682 KKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQK--------- 732
K P+++ K ++ + +++ +L PA R+ +A + EE ++
Sbjct: 639 PNSKSPREVPSPKV-IKTPVVKKTESPIKLSPATPSRKRSVAVSDEEEVEEEAERRKERC 697
Query: 733 -----ILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIRE 774
++K + K + L ++ E + K + + ++R RE
Sbjct: 698 KRGRFVVKEEKKDSNELSDSAGEEDSADLKRAQKDKGLHVEVRVNRE 744
>gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens]
Length = 250
Score = 43.9 bits (102), Expect = 7e-04
Identities = 40/147 (27%), Positives = 72/147 (48%), Gaps = 10/147 (6%)
Query: 642 ESPPPRPKLSA--LAEAKKLAA--ITKLRAKGQV--LTKTNPNSIKKKQKDPQDILEVKE 695
E PRPKL+A + E +K+ I K R + L + + ++K+ ++++ +KE
Sbjct: 27 EEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKE 86
Query: 696 RVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAEA--EMQE 753
R+EK + +AE + A K+R Q E + ++ AK + LK+ +A M
Sbjct: 87 RIEKRR--AERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGA 144
Query: 754 RYFEPLVKKEQMEEKMRNIREVKCRVV 780
Y L K +Q K + RE+K +++
Sbjct: 145 NYSSYLAKADQKRGKKQTAREMKKKIL 171
>gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens]
Length = 258
Score = 43.9 bits (102), Expect = 7e-04
Identities = 40/147 (27%), Positives = 72/147 (48%), Gaps = 10/147 (6%)
Query: 642 ESPPPRPKLSA--LAEAKKLAA--ITKLRAKGQV--LTKTNPNSIKKKQKDPQDILEVKE 695
E PRPKL+A + E +K+ I K R + L + + ++K+ ++++ +KE
Sbjct: 35 EEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKE 94
Query: 696 RVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAEA--EMQE 753
R+EK + +AE + A K+R Q E + ++ AK + LK+ +A M
Sbjct: 95 RIEKRR--AERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGA 152
Query: 754 RYFEPLVKKEQMEEKMRNIREVKCRVV 780
Y L K +Q K + RE+K +++
Sbjct: 153 NYSSYLAKADQKRGKKQTAREMKKKIL 179
>gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens]
Length = 250
Score = 43.9 bits (102), Expect = 7e-04
Identities = 40/147 (27%), Positives = 72/147 (48%), Gaps = 10/147 (6%)
Query: 642 ESPPPRPKLSA--LAEAKKLAA--ITKLRAKGQV--LTKTNPNSIKKKQKDPQDILEVKE 695
E PRPKL+A + E +K+ I K R + L + + ++K+ ++++ +KE
Sbjct: 27 EEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKE 86
Query: 696 RVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAEA--EMQE 753
R+EK + +AE + A K+R Q E + ++ AK + LK+ +A M
Sbjct: 87 RIEKRR--AERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGA 144
Query: 754 RYFEPLVKKEQMEEKMRNIREVKCRVV 780
Y L K +Q K + RE+K +++
Sbjct: 145 NYSSYLAKADQKRGKKQTAREMKKKIL 171
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 43.9 bits (102), Expect = 7e-04
Identities = 49/214 (22%), Positives = 85/214 (39%), Gaps = 17/214 (7%)
Query: 18 NESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEADDGETGETR----DEKEN 73
N +A D SEE + + E + E +D + E + D E+ ETR + EN
Sbjct: 76 NLNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSEN 135
Query: 74 LATLFGDMEDLTDEE--EVPASQSTENRVLPAPAPRREKTNEELQEELRNLQEQMKALQE 131
L G D +E+ + PAS S + +PA E T + L+ ++ + E + +
Sbjct: 136 EELLNGHASDSENEDVGKHPASDSEIEELQKSPASDSE-TEDALKPQISD-SESEEPPRH 193
Query: 132 QLKVTTIKQTASPARLQKSPEKSPRPPLKERRVQ---RIQESTCFSAELDVPALPRTKRV 188
Q + ++ P E+ P+P + + + R Q S + EL P R+
Sbjct: 194 QASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKP------RI 247
Query: 189 ARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKP 222
+ + PP ++S S P + P
Sbjct: 248 SDSESEDPPRHQASDSENEELPKPRISDSESEDP 281
>gi|112789538 troponin T3, skeletal, fast isoform 2 [Homo sapiens]
Length = 256
Score = 43.1 bits (100), Expect = 0.001
Identities = 39/149 (26%), Positives = 73/149 (48%), Gaps = 10/149 (6%)
Query: 640 YDESPPPRPKLSA--LAEAKKLAA--ITKLRAKGQV--LTKTNPNSIKKKQKDPQDILEV 693
++ PRPKL+A + E +K+ I K R + L + + ++K+ ++++ +
Sbjct: 31 HEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVAL 90
Query: 694 KERVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAEA--EM 751
KER+EK + +AE + A K+R Q E + ++ AK + LK+ +A M
Sbjct: 91 KERIEKRR--AERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSM 148
Query: 752 QERYFEPLVKKEQMEEKMRNIREVKCRVV 780
Y L K +Q K + RE+K +++
Sbjct: 149 GANYSSYLAKADQKRGKKQTAREMKKKIL 177
>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
sapiens]
Length = 691
Score = 43.1 bits (100), Expect = 0.001
Identities = 29/103 (28%), Positives = 54/103 (52%), Gaps = 5/103 (4%)
Query: 521 LMDLPTCGARNLKQHLAKATASGIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQ 580
++ LPT N++ +A A A GIM P ++++ A++ L Q Q++ +++ ++ Q
Sbjct: 138 VLTLPTANLTNIQGLVAAAAAGGIMTLP---LQNLQATSSLNSQLQQLQLQLQQQQQQQQ 194
Query: 581 KRFLQSSSEVESPA--VPSSSRQPPAQPPRTGSEFPRLEGAPA 621
++ S+++ PA PS S+Q P QP P + PA
Sbjct: 195 QQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPA 237
Score = 31.6 bits (70), Expect = 3.4
Identities = 35/134 (26%), Positives = 61/134 (45%), Gaps = 14/134 (10%)
Query: 112 NEELQEELRNLQEQMKALQEQLKVTTIKQTASPARLQKSPEKSPRPPLKERRVQR----I 167
N +LQ+ LQ+Q + Q+Q +T Q PA ++P +S + PL+ Q+
Sbjct: 176 NSQLQQLQLQLQQQQQQQQQQPPPST-NQHPQPA--PQAPSQSQQQPLQPTPPQQPPPAS 232
Query: 168 QESTCFSAELDVPALPRTKRV-ARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGIT 226
Q+ +++L P+ + + + + P P SS S P +P Q+ PS +T
Sbjct: 233 QQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSS---SPPQKPSQSPGHGLPSPLT 289
Query: 227 RG---QIVGTPGSS 237
Q+V P +S
Sbjct: 290 PPNPLQLVNNPLAS 303
>gi|164419758 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 42.7 bits (99), Expect = 0.001
Identities = 57/251 (22%), Positives = 90/251 (35%), Gaps = 50/251 (19%)
Query: 50 GDGESYTEEADDGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRRE 109
G +S +E + + + E+ E+E + ED DEEE + S
Sbjct: 472 GLAKSSSESSSEESSSESSSEEE-------EEEDEEDEEEEESESSD------------- 511
Query: 110 KTNEELQEELRNLQEQMKALQEQLKVTTIKQTASPARLQKSPEKSPRPPLKERRVQRIQE 169
+ EE L LQEQ++A+ EQL + + P R ++ EK K+R+ ++ +
Sbjct: 512 -SEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKK-----KKRKAEKHRG 565
Query: 170 STCFSAELDVPALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQ 229
+ P PR PP PK S S S PSG G
Sbjct: 566 RAGADEDDKGPRAPR-----------PPQPKKSKKASGSGGGSAALGPSGFGPSG---GS 611
Query: 230 IVGTPGSSGETTQPICVEAFSGLRLRRPRVSSTEMNK-------KMTGRKL---IRLSQI 279
P + +T P + R S + + K+ G KL + + Q
Sbjct: 612 GTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQA 671
Query: 280 KEKMAREKLEE 290
+E R+ E
Sbjct: 672 REPSLRDSNPE 682
>gi|4826806 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 42.7 bits (99), Expect = 0.001
Identities = 57/251 (22%), Positives = 90/251 (35%), Gaps = 50/251 (19%)
Query: 50 GDGESYTEEADDGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRRE 109
G +S +E + + + E+ E+E + ED DEEE + S
Sbjct: 472 GLAKSSSESSSEESSSESSSEEE-------EEEDEEDEEEEESESSD------------- 511
Query: 110 KTNEELQEELRNLQEQMKALQEQLKVTTIKQTASPARLQKSPEKSPRPPLKERRVQRIQE 169
+ EE L LQEQ++A+ EQL + + P R ++ EK K+R+ ++ +
Sbjct: 512 -SEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKK-----KKRKAEKHRG 565
Query: 170 STCFSAELDVPALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQ 229
+ P PR PP PK S S S PSG G
Sbjct: 566 RAGADEDDKGPRAPR-----------PPQPKKSKKASGSGGGSAALGPSGFGPSG---GS 611
Query: 230 IVGTPGSSGETTQPICVEAFSGLRLRRPRVSSTEMNK-------KMTGRKL---IRLSQI 279
P + +T P + R S + + K+ G KL + + Q
Sbjct: 612 GTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQA 671
Query: 280 KEKMAREKLEE 290
+E R+ E
Sbjct: 672 REPSLRDSNPE 682
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 42.7 bits (99), Expect = 0.001
Identities = 83/386 (21%), Positives = 157/386 (40%), Gaps = 47/386 (12%)
Query: 405 LRDCEYCQYHVQAQYKKLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVS 464
LR + V+ + KKL A+ +LQS S G R L +++ + V
Sbjct: 1240 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGE------RARAELNDKVHK---LQNEVE 1290
Query: 465 SASYAASIAAAVAPK-KKIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEE---FKE 520
S + + A A K K +LS+ + L+ +ETRQKL + K EE ++
Sbjct: 1291 SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQD 1350
Query: 521 LMDLPTCGARNLKQHLAKATASGIMGSPKPAIKSISASALLKQQKQR----------MLE 570
+D +NL++H++ + S K S L++ K+R E
Sbjct: 1351 QLDEEMEAKQNLERHISTLNIQ-LSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYE 1409
Query: 571 MRRRKSEEIQKRFLQSSSEVESPAVP-SSSRQPPAQPPRTGSEFPRLEGAPATMTPKLGR 629
+ ++++K + E++ V + RQ + + +F +L ++ K
Sbjct: 1410 EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK--- 1466
Query: 630 GVLEGDDVLFYDESPPPRPKLSALAEAKKLAAITKLRAKGQVLTKTN--PNSIKKKQKDP 687
+ DE R + A A K+ A++ RA + L + K + +
Sbjct: 1467 ---------YADE----RDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 1513
Query: 688 QDILEVKERVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEA 747
+D++ K+ V KN +++ LE ++ + QL LE +E Q AK + ++
Sbjct: 1514 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE-DELQATEDAKLRLEVNMQAL 1572
Query: 748 EAEMQERYFEPLVKKEQMEEKMRNIR 773
+ + + + + EQ EEK R ++
Sbjct: 1573 KGQFER---DLQARDEQNEEKRRQLQ 1595
Score = 30.8 bits (68), Expect = 5.7
Identities = 33/134 (24%), Positives = 63/134 (47%), Gaps = 19/134 (14%)
Query: 655 EAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTM-FSSQAED---- 709
E +K +TKL+ K + + +KK++K Q++ ++K ++E + F Q D
Sbjct: 1018 EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQ 1077
Query: 710 --ELEPARKKRREQ----LAYLESEEFQKILKAKSKHTGILKEAE---AEMQERYFEPLV 760
EL+ K+ E+ LA L+ E QK K ++E E +++QE
Sbjct: 1078 IAELKMQLAKKEEELQAALARLDDEIAQKNNALKK-----IRELEGHISDLQEDLDSERA 1132
Query: 761 KKEQMEEKMRNIRE 774
+ + E++ R++ E
Sbjct: 1133 ARNKAEKQKRDLGE 1146
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 42.7 bits (99), Expect = 0.001
Identities = 83/386 (21%), Positives = 157/386 (40%), Gaps = 47/386 (12%)
Query: 405 LRDCEYCQYHVQAQYKKLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVS 464
LR + V+ + KKL A+ +LQS S G R L +++ + V
Sbjct: 1247 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGE------RARAELNDKVHK---LQNEVE 1297
Query: 465 SASYAASIAAAVAPK-KKIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEE---FKE 520
S + + A A K K +LS+ + L+ +ETRQKL + K EE ++
Sbjct: 1298 SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQD 1357
Query: 521 LMDLPTCGARNLKQHLAKATASGIMGSPKPAIKSISASALLKQQKQR----------MLE 570
+D +NL++H++ + S K S L++ K+R E
Sbjct: 1358 QLDEEMEAKQNLERHISTLNIQ-LSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYE 1416
Query: 571 MRRRKSEEIQKRFLQSSSEVESPAVP-SSSRQPPAQPPRTGSEFPRLEGAPATMTPKLGR 629
+ ++++K + E++ V + RQ + + +F +L ++ K
Sbjct: 1417 EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK--- 1473
Query: 630 GVLEGDDVLFYDESPPPRPKLSALAEAKKLAAITKLRAKGQVLTKTN--PNSIKKKQKDP 687
+ DE R + A A K+ A++ RA + L + K + +
Sbjct: 1474 ---------YADE----RDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 1520
Query: 688 QDILEVKERVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEA 747
+D++ K+ V KN +++ LE ++ + QL LE +E Q AK + ++
Sbjct: 1521 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE-DELQATEDAKLRLEVNMQAL 1579
Query: 748 EAEMQERYFEPLVKKEQMEEKMRNIR 773
+ + + + + EQ EEK R ++
Sbjct: 1580 KGQFER---DLQARDEQNEEKRRQLQ 1602
Score = 30.8 bits (68), Expect = 5.7
Identities = 33/134 (24%), Positives = 63/134 (47%), Gaps = 19/134 (14%)
Query: 655 EAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTM-FSSQAED---- 709
E +K +TKL+ K + + +KK++K Q++ ++K ++E + F Q D
Sbjct: 1025 EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQ 1084
Query: 710 --ELEPARKKRREQ----LAYLESEEFQKILKAKSKHTGILKEAE---AEMQERYFEPLV 760
EL+ K+ E+ LA L+ E QK K ++E E +++QE
Sbjct: 1085 IAELKMQLAKKEEELQAALARLDDEIAQKNNALKK-----IRELEGHISDLQEDLDSERA 1139
Query: 761 KKEQMEEKMRNIRE 774
+ + E++ R++ E
Sbjct: 1140 ARNKAEKQKRDLGE 1153
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 42.7 bits (99), Expect = 0.001
Identities = 83/386 (21%), Positives = 157/386 (40%), Gaps = 47/386 (12%)
Query: 405 LRDCEYCQYHVQAQYKKLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVS 464
LR + V+ + KKL A+ +LQS S G R L +++ + V
Sbjct: 1247 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGE------RARAELNDKVHK---LQNEVE 1297
Query: 465 SASYAASIAAAVAPK-KKIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEE---FKE 520
S + + A A K K +LS+ + L+ +ETRQKL + K EE ++
Sbjct: 1298 SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQD 1357
Query: 521 LMDLPTCGARNLKQHLAKATASGIMGSPKPAIKSISASALLKQQKQR----------MLE 570
+D +NL++H++ + S K S L++ K+R E
Sbjct: 1358 QLDEEMEAKQNLERHISTLNIQ-LSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYE 1416
Query: 571 MRRRKSEEIQKRFLQSSSEVESPAVP-SSSRQPPAQPPRTGSEFPRLEGAPATMTPKLGR 629
+ ++++K + E++ V + RQ + + +F +L ++ K
Sbjct: 1417 EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK--- 1473
Query: 630 GVLEGDDVLFYDESPPPRPKLSALAEAKKLAAITKLRAKGQVLTKTN--PNSIKKKQKDP 687
+ DE R + A A K+ A++ RA + L + K + +
Sbjct: 1474 ---------YADE----RDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 1520
Query: 688 QDILEVKERVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEA 747
+D++ K+ V KN +++ LE ++ + QL LE +E Q AK + ++
Sbjct: 1521 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE-DELQATEDAKLRLEVNMQAL 1579
Query: 748 EAEMQERYFEPLVKKEQMEEKMRNIR 773
+ + + + + EQ EEK R ++
Sbjct: 1580 KGQFER---DLQARDEQNEEKRRQLQ 1602
Score = 30.8 bits (68), Expect = 5.7
Identities = 33/134 (24%), Positives = 63/134 (47%), Gaps = 19/134 (14%)
Query: 655 EAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTM-FSSQAED---- 709
E +K +TKL+ K + + +KK++K Q++ ++K ++E + F Q D
Sbjct: 1025 EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQ 1084
Query: 710 --ELEPARKKRREQ----LAYLESEEFQKILKAKSKHTGILKEAE---AEMQERYFEPLV 760
EL+ K+ E+ LA L+ E QK K ++E E +++QE
Sbjct: 1085 IAELKMQLAKKEEELQAALARLDDEIAQKNNALKK-----IRELEGHISDLQEDLDSERA 1139
Query: 761 KKEQMEEKMRNIRE 774
+ + E++ R++ E
Sbjct: 1140 ARNKAEKQKRDLGE 1153
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 42.7 bits (99), Expect = 0.001
Identities = 83/386 (21%), Positives = 157/386 (40%), Gaps = 47/386 (12%)
Query: 405 LRDCEYCQYHVQAQYKKLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVS 464
LR + V+ + KKL A+ +LQS S G R L +++ + V
Sbjct: 1240 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGE------RARAELNDKVHK---LQNEVE 1290
Query: 465 SASYAASIAAAVAPK-KKIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEE---FKE 520
S + + A A K K +LS+ + L+ +ETRQKL + K EE ++
Sbjct: 1291 SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQD 1350
Query: 521 LMDLPTCGARNLKQHLAKATASGIMGSPKPAIKSISASALLKQQKQR----------MLE 570
+D +NL++H++ + S K S L++ K+R E
Sbjct: 1351 QLDEEMEAKQNLERHISTLNIQ-LSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYE 1409
Query: 571 MRRRKSEEIQKRFLQSSSEVESPAVP-SSSRQPPAQPPRTGSEFPRLEGAPATMTPKLGR 629
+ ++++K + E++ V + RQ + + +F +L ++ K
Sbjct: 1410 EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK--- 1466
Query: 630 GVLEGDDVLFYDESPPPRPKLSALAEAKKLAAITKLRAKGQVLTKTN--PNSIKKKQKDP 687
+ DE R + A A K+ A++ RA + L + K + +
Sbjct: 1467 ---------YADE----RDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 1513
Query: 688 QDILEVKERVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEA 747
+D++ K+ V KN +++ LE ++ + QL LE +E Q AK + ++
Sbjct: 1514 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE-DELQATEDAKLRLEVNMQAL 1572
Query: 748 EAEMQERYFEPLVKKEQMEEKMRNIR 773
+ + + + + EQ EEK R ++
Sbjct: 1573 KGQFER---DLQARDEQNEEKRRQLQ 1595
Score = 30.8 bits (68), Expect = 5.7
Identities = 33/134 (24%), Positives = 63/134 (47%), Gaps = 19/134 (14%)
Query: 655 EAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTM-FSSQAED---- 709
E +K +TKL+ K + + +KK++K Q++ ++K ++E + F Q D
Sbjct: 1018 EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQ 1077
Query: 710 --ELEPARKKRREQ----LAYLESEEFQKILKAKSKHTGILKEAE---AEMQERYFEPLV 760
EL+ K+ E+ LA L+ E QK K ++E E +++QE
Sbjct: 1078 IAELKMQLAKKEEELQAALARLDDEIAQKNNALKK-----IRELEGHISDLQEDLDSERA 1132
Query: 761 KKEQMEEKMRNIRE 774
+ + E++ R++ E
Sbjct: 1133 ARNKAEKQKRDLGE 1146
>gi|187173290 troponin T1, skeletal, slow isoform b [Homo sapiens]
Length = 262
Score = 42.4 bits (98), Expect = 0.002
Identities = 49/217 (22%), Positives = 92/217 (42%), Gaps = 33/217 (15%)
Query: 568 MLEMRRRKSEEIQKRFLQSSSEVESPAVPSSSRQPPAQPPRTGSEFPRLEGAPATMTPKL 627
M + ++ EE Q + E E+P P +P + P+ P P + PK+
Sbjct: 1 MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPK-----PSRPVVPPLIPPKI 55
Query: 628 GRGVLEGDDVLFYDESPPPRPKLSALAEAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDP 687
EG+ V F D K L E + L + ++++K+
Sbjct: 56 P----EGERVDFDDIHRKRMEK--DLLELQTLIDV----------------HFEQRKKEE 93
Query: 688 QDILEVKERVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQK---ILKAKSKHTGIL 744
++++ +KER+E+ S+ ++ +K RE+ A L E+ +K K +++
Sbjct: 94 EELVALKERIERR---RSERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKK 150
Query: 745 KEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRVVT 781
K+ + M + LVK EQ K + RE+K R+++
Sbjct: 151 KKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILS 187
>gi|187173288 troponin T1, skeletal, slow isoform a [Homo sapiens]
Length = 278
Score = 42.4 bits (98), Expect = 0.002
Identities = 49/217 (22%), Positives = 92/217 (42%), Gaps = 33/217 (15%)
Query: 568 MLEMRRRKSEEIQKRFLQSSSEVESPAVPSSSRQPPAQPPRTGSEFPRLEGAPATMTPKL 627
M + ++ EE Q + E E+P P +P + P+ P P + PK+
Sbjct: 1 MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPK-----PSRPVVPPLIPPKI 55
Query: 628 GRGVLEGDDVLFYDESPPPRPKLSALAEAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDP 687
EG+ V F D K L E + L + ++++K+
Sbjct: 56 P----EGERVDFDDIHRKRMEK--DLLELQTLIDV----------------HFEQRKKEE 93
Query: 688 QDILEVKERVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQK---ILKAKSKHTGIL 744
++++ +KER+E+ S+ ++ +K RE+ A L E+ +K K +++
Sbjct: 94 EELVALKERIERR---RSERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKK 150
Query: 745 KEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRVVT 781
K+ + M + LVK EQ K + RE+K R+++
Sbjct: 151 KKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILS 187
>gi|209862789 microtubule associated monoxygenase, calponin and LIM
domain containing 3 isoform 1 [Homo sapiens]
Length = 2002
Score = 42.4 bits (98), Expect = 0.002
Identities = 76/323 (23%), Positives = 122/323 (37%), Gaps = 37/323 (11%)
Query: 3 EEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEADDG 62
EEE+ ++ + SA +EN+ + EP A+ +GE+ E+ D G
Sbjct: 1049 EEEERMAPAS-----ESSASGAPLDENDLEEDVDSEP--------AEIEGEA-AEDGDPG 1094
Query: 63 ETGETRDEKENLATLFGDME-------DLTDEEEVPASQSTENRVLPAPAPRREKTNEEL 115
+TG D+ ++ + D + E E+ S + LPA +E+ +
Sbjct: 1095 DTGAELDDDQHWSDSPSDADRELRLPCPAEGEAELELRVSEDEEKLPASPKHQERGPSQA 1154
Query: 116 QEELRNLQEQMKALQEQLKVTTIKQTASP---ARLQKSPEKS--PRPPLKERRVQRIQES 170
+R+ QE +T P A +KSPE+ P P L + + + S
Sbjct: 1155 TSPIRSPQESALLFIPVHSPSTEGPQLPPVPAATQEKSPEERLFPEPLLPKEKPKADAPS 1214
Query: 171 TCFSAELDVPALPRTKRVARTPKA-SPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQ 229
+ + + P T ARTP + P P+ + T PS PL S+ +PS
Sbjct: 1215 DLKAVHSPIRSQPVTLPEARTPVSPGSPQPQPPVAASTPPPS-PLPICSQPQPS---TEA 1270
Query: 230 IVGTPGSSGETTQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAREKLE 289
V +P S QP A + L V S K G L + E + R L
Sbjct: 1271 TVPSPTQSPIRFQP--APAKTSTPLAPLPVQSQSDTKDRLGSPL----AVDEALRRSDLV 1324
Query: 290 EIDWVTFGVILKKVTPQSVNSGK 312
E W+ I + + V+ K
Sbjct: 1325 EEFWMKSAEIRRSLGLTPVDRSK 1347
>gi|58535453 CDK5 regulatory subunit associated protein 2 isoform b
[Homo sapiens]
Length = 1814
Score = 42.0 bits (97), Expect = 0.002
Identities = 65/340 (19%), Positives = 142/340 (41%), Gaps = 49/340 (14%)
Query: 489 LVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKATASGIMGSP 548
LV+ + +I+E + L + + C +E K M P ++++ G+ +P
Sbjct: 214 LVLDEKDRLIEELKLSLKSKEALIQCLKEEKSQMACPD-------ENVSSGELRGLCAAP 266
Query: 549 KPAIKSISASALLKQQKQR---------MLEMRRRKSEEI---QKRFLQSSSEVESPAVP 596
+ + + +A ++ QK+R + E R K EI +K L+ ++ +
Sbjct: 267 REEKERETEAAQMEHQKERNSFEERIQALEEDLREKEREIATEKKNSLKRDKAIQGLTMA 326
Query: 597 SSSRQPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEA 656
S++ + SE +L A A L + + E +AL+
Sbjct: 327 LKSKEKKVE--ELNSEIEKLSAAFAKAREALQKAQTQ--------EFQGSEDYETALSGK 376
Query: 657 KKLAAITKLRAKGQVLTKTNPN-----SIKKKQKDPQDILEVKERVEKNTMFSSQAEDEL 711
+ L+A + Q LTK+ N SIKK ++ D+ + +ER+EK+ + + + +
Sbjct: 377 EALSAALR----SQNLTKSTENHRLRRSIKKITQELSDLQQERERLEKDLEEAHREKSKG 432
Query: 712 EPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAEAEM--QERYFEPLVKK------- 762
+ + R ++ L +E ++ ++++ +L E+ ++ QE+ + L +
Sbjct: 433 DCTIRDLRNEVEKLRNEVNEREKAMENRYKSLLSESNKKLHNQEQVIKHLTESTNQKDVL 492
Query: 763 -EQMEEKMRNIREVKCRVVTCKTCAYTHFKLL-ETCVSEQ 800
++ EK + + C ++ + L+ E C S+Q
Sbjct: 493 LQKFNEKDLEVIQQNCYLMAAEDLELRSEGLITEKCSSQQ 532
Score = 30.8 bits (68), Expect = 5.7
Identities = 35/151 (23%), Positives = 62/151 (41%), Gaps = 14/151 (9%)
Query: 71 KENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELRNLQEQMKALQ 130
+E+L+ +E L E AS EN L +E+ N++L +E+R +++ +Q
Sbjct: 1481 RESLSRKTVSLEHLQREY---ASVKEENERLQKEGSEKERHNQQLIQEVRCSGQELSRVQ 1537
Query: 131 EQLKVTTIKQTASPARLQKSPEKSPRPPLKERRVQRIQESTCFSAE-------LDVPALP 183
E++K+ + + LQ + + +R+++ + E D
Sbjct: 1538 EEVKLRQQLLSQNDKLLQSLRVELKAYEKLDEEHRRLRDGDKYPMESDNSFDLFDSSQAV 1597
Query: 184 RTKRVARTPKASPPDPKS----SSSRMTSAP 210
K V+ TP S D S S S TS P
Sbjct: 1598 TPKSVSETPPLSGNDTDSLSCDSGSSATSTP 1628
>gi|58535451 CDK5 regulatory subunit associated protein 2 isoform a
[Homo sapiens]
Length = 1893
Score = 42.0 bits (97), Expect = 0.002
Identities = 65/340 (19%), Positives = 142/340 (41%), Gaps = 49/340 (14%)
Query: 489 LVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKATASGIMGSP 548
LV+ + +I+E + L + + C +E K M P ++++ G+ +P
Sbjct: 214 LVLDEKDRLIEELKLSLKSKEALIQCLKEEKSQMACPD-------ENVSSGELRGLCAAP 266
Query: 549 KPAIKSISASALLKQQKQR---------MLEMRRRKSEEI---QKRFLQSSSEVESPAVP 596
+ + + +A ++ QK+R + E R K EI +K L+ ++ +
Sbjct: 267 REEKERETEAAQMEHQKERNSFEERIQALEEDLREKEREIATEKKNSLKRDKAIQGLTMA 326
Query: 597 SSSRQPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEA 656
S++ + SE +L A A L + + E +AL+
Sbjct: 327 LKSKEKKVE--ELNSEIEKLSAAFAKAREALQKAQTQ--------EFQGSEDYETALSGK 376
Query: 657 KKLAAITKLRAKGQVLTKTNPN-----SIKKKQKDPQDILEVKERVEKNTMFSSQAEDEL 711
+ L+A + Q LTK+ N SIKK ++ D+ + +ER+EK+ + + + +
Sbjct: 377 EALSAALR----SQNLTKSTENHRLRRSIKKITQELSDLQQERERLEKDLEEAHREKSKG 432
Query: 712 EPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAEAEM--QERYFEPLVKK------- 762
+ + R ++ L +E ++ ++++ +L E+ ++ QE+ + L +
Sbjct: 433 DCTIRDLRNEVEKLRNEVNEREKAMENRYKSLLSESNKKLHNQEQVIKHLTESTNQKDVL 492
Query: 763 -EQMEEKMRNIREVKCRVVTCKTCAYTHFKLL-ETCVSEQ 800
++ EK + + C ++ + L+ E C S+Q
Sbjct: 493 LQKFNEKDLEVIQQNCYLMAAEDLELRSEGLITEKCSSQQ 532
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/133 (24%), Positives = 58/133 (43%), Gaps = 6/133 (4%)
Query: 80 DMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELRNLQEQMKALQEQLKVTTIK 139
+ E + EE+ +Q TE +E EE +EE +E+ + +E+ K +
Sbjct: 451 EKETVIVEEQTEETQVTEE---VTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAE 507
Query: 140 QTASPARLQKSPEKSPRPPLKERRVQRIQESTCFSAELDVPALPRTKRVARTPKASPPDP 199
+ ASP + KSP K E + +E+ + +V + + K A+ SPP+
Sbjct: 508 EAASPEKEAKSPVKEEAKSPAEAKSPEKEEA---KSPAEVKSPEKAKSPAKEEAKSPPEA 564
Query: 200 KSSSSRMTSAPSQ 212
KS +P++
Sbjct: 565 KSPEKEEAKSPAE 577
Score = 35.4 bits (80), Expect = 0.23
Identities = 46/235 (19%), Positives = 83/235 (35%), Gaps = 27/235 (11%)
Query: 53 ESYTEEADDGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTN 112
E TEE E +EKE + E +EE + T++ A ++
Sbjct: 458 EEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAK 517
Query: 113 EELQEELRNLQEQMKALQEQLKVTTIKQTASPARLQKSPEKSPRPPLKERRVQRIQESTC 172
++EE ++ E +E+ K SPA + KSPEK+ P +E +
Sbjct: 518 SPVKEEAKSPAEAKSPEKEEAK--------SPAEV-KSPEKAKSPAKEEAK--------- 559
Query: 173 FSAELDVPALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQIVG 232
+ P K + SP + KS + A + P + +
Sbjct: 560 --------SPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEK-AKSPVKE 610
Query: 233 TPGSSGETTQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAREK 287
S E P+ EA S ++ P + + ++ + + + +E + EK
Sbjct: 611 EAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEK 665
Score = 31.6 bits (70), Expect = 3.4
Identities = 34/155 (21%), Positives = 62/155 (40%), Gaps = 14/155 (9%)
Query: 103 APAPRREKTNEELQEELRNLQEQMKALQEQLKV-----TTIKQTASPARLQKSPEKSP-R 156
A A EK ++EE ++ ++ ++E+ K + +K+ A KSP K +
Sbjct: 686 AEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAK 745
Query: 157 PPLKERRVQRIQESTCFSAELDVPALPRTKRVARTPKASPPD----PKSSSSRMTSAPSQ 212
P K + ++ + S E PA K AR+P P+ P +
Sbjct: 746 SPEKAKSPEKAKTLDVKSPEAKTPA----KEEARSPADKFPEKAKSPVKEEVKSPEKAKS 801
Query: 213 PLQTISRNKPSGITRGQIVGTPGSSGETTQPICVE 247
PL+ ++ I + + V +P E Q + V+
Sbjct: 802 PLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVK 836
Score = 31.2 bits (69), Expect = 4.4
Identities = 34/186 (18%), Positives = 77/186 (41%), Gaps = 29/186 (15%)
Query: 47 DADGDGESYTEEADDGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAP 106
+A + + E+A E + ++ + L D + E+E+P + ++ V
Sbjct: 773 EARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAK--APEKEIPKKEEVKSPV------ 824
Query: 107 RREKTNEELQEELRNLQEQMKALQEQLKVTTIKQTASPARLQKSPEK-SPRPPLKERR-- 163
EE +E++ + KA +E+ T + ++ +++P+K +P+P ++E++
Sbjct: 825 ----KEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEP 880
Query: 164 -VQRIQESTCFSA-------------ELDVPALPRTKRVARTPKASPPDPKSSSSRMTSA 209
V++ +ES + E + PA K A+ + + K
Sbjct: 881 AVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKE 940
Query: 210 PSQPLQ 215
PS+P +
Sbjct: 941 PSKPAE 946
Score = 30.4 bits (67), Expect = 7.5
Identities = 45/193 (23%), Positives = 75/193 (38%), Gaps = 13/193 (6%)
Query: 589 EVESPAVPSSSRQPPAQPPRTGSEFPRLEG--APATMTPKLGRGVLEGDDVLFYDESPPP 646
EV+SP S + A+ P E P+ E +P K ++ +E P
Sbjct: 792 EVKSPEKAKSPLKEDAKAPE--KEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPA 849
Query: 647 RPKLSALAEAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQ 706
PK ++KK A K K +V K P K K+ + E E +K +
Sbjct: 850 TPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKE 909
Query: 707 AEDEL---EPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKE 763
A ++ E A+ K + ++A E ++ AK+K E + E+ K +
Sbjct: 910 APAKVEVKEDAKPKEKTEVAKKEPDD------AKAKEPSKPAEKKEAAPEKKDTKEEKAK 963
Query: 764 QMEEKMRNIREVK 776
+ EEK + + K
Sbjct: 964 KPEEKPKTEAKAK 976
>gi|16445033 ACRC protein [Homo sapiens]
Length = 691
Score = 42.0 bits (97), Expect = 0.002
Identities = 42/207 (20%), Positives = 87/207 (42%), Gaps = 22/207 (10%)
Query: 17 ENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEADDGETGETRDEKENLAT 76
++ A D +S+++ + + +A D D+ D E+ + +DD E + + + ++
Sbjct: 260 DDSEAPDDSSDDSEAPDDSSDDSEASD---DSSDDSEASDDSSDDSEAPDDKSDDSDVP- 315
Query: 77 LFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNE-ELQEELRNLQEQMKALQEQLKV 135
ED +D+ +VP S + L P P + NE ++ + L E A+ +
Sbjct: 316 -----EDKSDDSDVPDDNSDD---LEVPVPAEDLCNEGQIASDEEELVEAAAAVSQH--- 364
Query: 136 TTIKQTASPARLQKSPEKSPRPPLKERRVQRIQESTCFSAELDVPALPRT-KRVARTPK- 193
++ A Q E +PP + E + E P + ++ KR ++T
Sbjct: 365 ----DSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTKTI 420
Query: 194 ASPPDPKSSSSRMTSAPSQPLQTISRN 220
PP + + ++ P + QT ++N
Sbjct: 421 VEPPRKRQTKTKNIVEPPRKRQTKTKN 447
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 41.6 bits (96), Expect = 0.003
Identities = 36/149 (24%), Positives = 70/149 (46%), Gaps = 5/149 (3%)
Query: 83 DLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELRNLQEQMKALQEQLKVTTIKQTA 142
DL + E+ + +N L A + E+ ELQ +LR++QE+ + +Q++L + +Q A
Sbjct: 646 DLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEA 705
Query: 143 SPARLQKSPEKSPR-PPLKERRVQRIQESTCFSAELDVPALPRTKRVARTPKASPPDPKS 201
+ +L++ +++ R + R VQ + A L+V R + V R + +
Sbjct: 706 ATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEV----RLQAVERDRQDLAEQLQG 761
Query: 202 SSSRMTSAPSQPLQTISRNKPSGITRGQI 230
SS S + +N +T+GQ+
Sbjct: 762 LSSAKELLESSLFEAQQQNSVIEVTKGQL 790
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 41.6 bits (96), Expect = 0.003
Identities = 57/245 (23%), Positives = 97/245 (39%), Gaps = 35/245 (14%)
Query: 543 GIMGSPKPAIK-----SISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPA--- 594
G SPK ++ S SA + K + +RR S E K +S SPA
Sbjct: 499 GTTASPKGRVRRKEEAKESPSAAGPEDKS---QSKRRASNE--KESAAPASPAPSPAPSP 553
Query: 595 --VPSSSRQPPAQPPRTGSEF--PRLEGAPATMT-PKLGRGVLEGDDVLFYDESPPPRPK 649
P QPPA+ P + P P T + P G E L ++ R +
Sbjct: 554 TPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAREQ 613
Query: 650 LSALAEAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAED 709
+ ++L A R + + L + +++ E + R E+ +QAE
Sbjct: 614 REREEQERRLQAERDKRMREEQLAREAEARAEREA-------EARRREEQEAREKAQAEQ 666
Query: 710 ELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKM 769
E + +K++E+ EE ++ + KH ++ E E QER ++++EE M
Sbjct: 667 EEQERLQKQKEEAEARSREEAERQRLEREKH---FQQQEQERQER-------RKRLEEIM 716
Query: 770 RNIRE 774
+ R+
Sbjct: 717 KRTRK 721
Score = 33.9 bits (76), Expect = 0.68
Identities = 40/182 (21%), Positives = 73/182 (40%), Gaps = 22/182 (12%)
Query: 51 DGESYTEEADDGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREK 110
+ E+ E + E ++ +E + E L ++E ++S E A R E+
Sbjct: 639 EAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREE----AERQRLER 694
Query: 111 TNEELQEELRNLQEQMKALQEQLKVTTIKQTASPARLQKSPE-----KSPRPPLKERRVQ 165
+ Q++ + QE+ K L+E +K T + + + Q S E SP P
Sbjct: 695 -EKHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGSSPEP-------- 745
Query: 166 RIQESTCFSAELDVPALPRTKRVARTPKASPPD---PKSSSSRMTSAPSQPLQTISRNKP 222
++ S L A+ + + + + P+ S P P S + + P+ S N P
Sbjct: 746 -VKAVEARSPGLQKEAVQKEEPIPQEPQWSLPSKELPASLVNGLQPLPAHQENGFSTNGP 804
Query: 223 SG 224
SG
Sbjct: 805 SG 806
Score = 31.2 bits (69), Expect = 4.4
Identities = 31/159 (19%), Positives = 74/159 (46%), Gaps = 6/159 (3%)
Query: 66 ETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELRNLQEQ 125
E R+ +E L + + EE++ A ++ A A RRE+ +E +E+ + QE+
Sbjct: 612 EQREREEQERRLQAERDKRMREEQL-AREAEARAEREAEARRREE--QEAREKAQAEQEE 668
Query: 126 MKALQEQLKVTTI--KQTASPARLQKSPEKSPRPPLKERRVQRIQESTCFSAELDVPALP 183
+ LQ+Q + ++ A RL++ + ++ R +R++E + + +V +
Sbjct: 669 QERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEV-SET 727
Query: 184 RTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKP 222
+ K+ ++ A+ P+ + +P + + + +P
Sbjct: 728 KQKQDSKEANANGSSPEPVKAVEARSPGLQKEAVQKEEP 766
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 41.2 bits (95), Expect = 0.004
Identities = 49/227 (21%), Positives = 93/227 (40%), Gaps = 35/227 (15%)
Query: 2 DEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDA------------- 48
DE+ + LTA+ EE A+ E+ + EP+A +E A
Sbjct: 464 DEKSEMEEALTAITEE--LAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVK 521
Query: 49 DGDGESYTEEADDGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRR 108
+ +GE EE + E E K + A G ++ + E+E + E
Sbjct: 522 EEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGE----------- 570
Query: 109 EKTNEELQEELRNLQEQMKALQEQLKVTTIKQTASPARLQKSPEKS----PRPPLKERRV 164
T E + E +E+ K ++ +V T ++ + A+++K PEK+ P+ P++E+
Sbjct: 571 --TEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEK-PEKAKSPVPKSPVEEKGK 627
Query: 165 QRIQESTC-FSAELDVPALPRTKRVARTPKASPPDPKSSSSRMTSAP 210
+ +S + VP P + ++P P + S ++ +P
Sbjct: 628 SPVPKSPVEEKGKSPVPKSP-VEEKGKSPVPKSPVEEKGKSPVSKSP 673
Score = 32.0 bits (71), Expect = 2.6
Identities = 35/176 (19%), Positives = 74/176 (42%), Gaps = 12/176 (6%)
Query: 585 QSSSEVESPAVPSSSRQPPAQPP---RTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYD 641
+ S V V + P ++ P + S P+ A ++G+G + ++
Sbjct: 651 KGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVK 710
Query: 642 ESPPPRP------KLSALAEAKKLAAITKLRAKGQVLTKTNPNSI---KKKQKDPQDILE 692
E+P K + E KK + K A +V+T T + K+ +++ + + +
Sbjct: 711 EAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQ 770
Query: 693 VKERVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAE 748
KE+ + S+ E + A+ R+E +A E ++ ++ ++K G +E E
Sbjct: 771 EKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEE 826
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 41.2 bits (95), Expect = 0.004
Identities = 49/227 (21%), Positives = 93/227 (40%), Gaps = 35/227 (15%)
Query: 2 DEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDA------------- 48
DE+ + LTA+ EE A+ E+ + EP+A +E A
Sbjct: 88 DEKSEMEEALTAITEE--LAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVK 145
Query: 49 DGDGESYTEEADDGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRR 108
+ +GE EE + E E K + A G ++ + E+E + E
Sbjct: 146 EEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGE----------- 194
Query: 109 EKTNEELQEELRNLQEQMKALQEQLKVTTIKQTASPARLQKSPEKS----PRPPLKERRV 164
T E + E +E+ K ++ +V T ++ + A+++K PEK+ P+ P++E+
Sbjct: 195 --TEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEK-PEKAKSPVPKSPVEEKGK 251
Query: 165 QRIQESTC-FSAELDVPALPRTKRVARTPKASPPDPKSSSSRMTSAP 210
+ +S + VP P + ++P P + S ++ +P
Sbjct: 252 SPVPKSPVEEKGKSPVPKSP-VEEKGKSPVPKSPVEEKGKSPVSKSP 297
Score = 32.0 bits (71), Expect = 2.6
Identities = 35/176 (19%), Positives = 74/176 (42%), Gaps = 12/176 (6%)
Query: 585 QSSSEVESPAVPSSSRQPPAQPP---RTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYD 641
+ S V V + P ++ P + S P+ A ++G+G + ++
Sbjct: 275 KGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVK 334
Query: 642 ESPPPRP------KLSALAEAKKLAAITKLRAKGQVLTKTNPNSI---KKKQKDPQDILE 692
E+P K + E KK + K A +V+T T + K+ +++ + + +
Sbjct: 335 EAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQ 394
Query: 693 VKERVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAE 748
KE+ + S+ E + A+ R+E +A E ++ ++ ++K G +E E
Sbjct: 395 EKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEE 450
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 41.2 bits (95), Expect = 0.004
Identities = 37/127 (29%), Positives = 65/127 (51%), Gaps = 10/127 (7%)
Query: 653 LAEAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELE 712
+ E +K A KL+ + L I +KQ P++I E +ER EK + E E E
Sbjct: 473 MEEQRKAACAEKLKRLDEKL------GILEKQPSPEEIRE-RER-EKEREREKELEKEQE 524
Query: 713 PARKKRREQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNI 772
R+K RE+ + E+ +++ K + K + KE + E +E+ E +KE+ +KM+
Sbjct: 525 QEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQE-KEKELERQKEKEKELQKMKE- 582
Query: 773 REVKCRV 779
+E +C +
Sbjct: 583 QEKECEL 589
Score = 36.2 bits (82), Expect = 0.14
Identities = 41/181 (22%), Positives = 72/181 (39%), Gaps = 11/181 (6%)
Query: 57 EEADDGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQ 116
EE + E + R+ ++ L + E++ Q E + +RE E Q
Sbjct: 502 EEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQ 561
Query: 117 EELRNLQEQMKALQEQLKVTTIKQTASPARLQKSPEK-----SPRPPLKERRVQRIQ-ES 170
E+ + L+ Q + +E K +K+ L+K EK PR P E V++ + E+
Sbjct: 562 EKEKELERQKEKEKELQK---MKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESEN 618
Query: 171 TCFSAELDVPALPRTKRVAR--TPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRG 228
+C E V + R + TP +P+S S + S + ++ P R
Sbjct: 619 SCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQ 678
Query: 229 Q 229
Q
Sbjct: 679 Q 679
Score = 33.9 bits (76), Expect = 0.68
Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 13/102 (12%)
Query: 681 KKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRREQLAYLESE---EFQKILKAK 737
K+++KD + E ++ +EK + + E+E RK+ +E+ + E E QK +K +
Sbjct: 529 KEREKDRERQQEKEKELEKE----QEKQREMEKERKQEKEKELERQKEKEKELQK-MKEQ 583
Query: 738 SKHTGILKEAE-----AEMQERYFEPLVKKEQMEEKMRNIRE 774
K + KE E E +E EP+V+K++ E E
Sbjct: 584 EKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEE 625
Score = 30.8 bits (68), Expect = 5.7
Identities = 25/98 (25%), Positives = 45/98 (45%), Gaps = 9/98 (9%)
Query: 78 FGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELRNLQEQMK-ALQEQL--- 133
F + + DE+E+ + + + A R K EE E R ++EQ K A E+L
Sbjct: 432 FPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREE---EERRMEEQRKAACAEKLKRL 488
Query: 134 --KVTTIKQTASPARLQKSPEKSPRPPLKERRVQRIQE 169
K+ +++ SP +++ + R KE ++ QE
Sbjct: 489 DEKLGILEKQPSPEEIREREREKEREREKELEKEQEQE 526
>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
[Homo sapiens]
Length = 517
Score = 40.4 bits (93), Expect = 0.007
Identities = 39/191 (20%), Positives = 71/191 (37%), Gaps = 14/191 (7%)
Query: 34 RENGEPDAFDELFDADGDGESYTEEADDGETGETRDEKENLATLF----------GDMED 83
++ + +AF++ D D +G+ +D + + E + A D +
Sbjct: 250 KKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSE 309
Query: 84 LTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELRNLQEQMKALQEQLKVTTIKQTAS 143
++EE+ P E AP P+ +K ++ EE + +E + + K+
Sbjct: 310 ESEEEKPPEEDKEEEEEKKAPTPQEKKRRKDSSEESDSSEESDIDSEASSALFMAKKKTP 369
Query: 144 PARLQKSPEKSPRPPLKERRVQRIQESTCFSAELDVPALPRTKRVARTPKAS----PPDP 199
P R +K S R + ST + L + KRV+ P A P
Sbjct: 370 PKRERKPSGGSSRGNSRPGTPSAEGGSTSSTLRAAASKLEQGKRVSEMPAAKRLRLDTGP 429
Query: 200 KSSSSRMTSAP 210
+S S + T P
Sbjct: 430 QSLSGKSTPQP 440
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,079,231
Number of Sequences: 37866
Number of extensions: 1858025
Number of successful extensions: 13527
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 84
Number of HSP's successfully gapped in prelim test: 739
Number of HSP's that attempted gapping in prelim test: 11021
Number of HSP's gapped (non-prelim): 3284
length of query: 874
length of database: 18,247,518
effective HSP length: 111
effective length of query: 763
effective length of database: 14,044,392
effective search space: 10715871096
effective search space used: 10715871096
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.