BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens] (953 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens] 1964 0.0 gi|33359217 ALS2 C-terminal like isoform 3 [Homo sapiens] 603 e-172 gi|40316935 alsin isoform 1 [Homo sapiens] 508 e-144 gi|153792461 radial spoke head 10 homolog B2 [Homo sapiens] 86 2e-16 gi|157502187 radial spoke head 10 homolog B [Homo sapiens] 86 2e-16 gi|13376267 MORN repeat containing 1 [Homo sapiens] 85 3e-16 gi|225690502 junctophilin 4 [Homo sapiens] 73 1e-12 gi|225690500 junctophilin 4 [Homo sapiens] 73 1e-12 gi|18254456 testis-specific gene A2 [Homo sapiens] 72 3e-12 gi|21704281 junctophilin 2 isoform 1 [Homo sapiens] 69 2e-11 gi|21704283 junctophilin 3 [Homo sapiens] 68 5e-11 gi|21735575 junctophilin 1 [Homo sapiens] 67 6e-11 gi|50355990 MORN repeat containing 3 [Homo sapiens] 67 8e-11 gi|149999376 MORN repeat containing 4 [Homo sapiens] 62 2e-09 gi|30520314 MORN repeat containing 4 [Homo sapiens] 62 2e-09 gi|29893812 junctophilin 2 isoform 2 [Homo sapiens] 62 3e-09 gi|75750529 ankyrin repeat and MYND domain containing 1 isoform ... 43 0.001 gi|40353729 Ras and Rab interactor 3 [Homo sapiens] 41 0.006 gi|75750531 ankyrin repeat and MYND domain containing 1 isoform ... 38 0.051 gi|18466802 Ras and Rab interactor 2 [Homo sapiens] 37 0.067 gi|224282170 MORN repeat containing 2 [Homo sapiens] 34 0.74 gi|108860690 chromosome 16 open reading frame 7 [Homo sapiens] 34 0.74 gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens] 33 1.7 gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens] 33 1.7 gi|110347420 structural maintenance of chromosomes 2 [Homo sapiens] 33 1.7 gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 32 2.2 gi|223278407 MORN repeat containing 5 [Homo sapiens] 32 2.8 gi|4506123 PRP18 pre-mRNA processing factor 18 homolog [Homo sap... 32 2.8 gi|82659109 retinoblastoma-associated factor 600 [Homo sapiens] 32 2.8 gi|18034775 PHD finger protein 20 [Homo sapiens] 32 3.7 >gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens] Length = 953 Score = 1964 bits (5088), Expect = 0.0 Identities = 953/953 (100%), Positives = 953/953 (100%) Query: 1 MCNPEEAALLRLEEVFSATLAHVNSLVLQPLLPAAPDPSDPWGRECLRLLQQLHKSSQQL 60 MCNPEEAALLRLEEVFSATLAHVNSLVLQPLLPAAPDPSDPWGRECLRLLQQLHKSSQQL Sbjct: 1 MCNPEEAALLRLEEVFSATLAHVNSLVLQPLLPAAPDPSDPWGRECLRLLQQLHKSSQQL 60 Query: 61 WEVTEESLHSLQERLRYPDSTGLESLLLLRGADRVLQAHIEYIESYTSCMVVQAFQKAAK 120 WEVTEESLHSLQERLRYPDSTGLESLLLLRGADRVLQAHIEYIESYTSCMVVQAFQKAAK Sbjct: 61 WEVTEESLHSLQERLRYPDSTGLESLLLLRGADRVLQAHIEYIESYTSCMVVQAFQKAAK 120 Query: 121 RRSEYWRGQRKALRQLLSGVSSEGSVGASLGQALHQPLAHHVQQYVLLLLSLGDTIGEHH 180 RRSEYWRGQRKALRQLLSGVSSEGSVGASLGQALHQPLAHHVQQYVLLLLSLGDTIGEHH Sbjct: 121 RRSEYWRGQRKALRQLLSGVSSEGSVGASLGQALHQPLAHHVQQYVLLLLSLGDTIGEHH 180 Query: 181 PTRELVVNAVTLFGNLQSFMKQELDQAVATQALWHTLRGRLRDVLCTPAHRLLQDSQDVP 240 PTRELVVNAVTLFGNLQSFMKQELDQAVATQALWHTLRGRLRDVLCTPAHRLLQDSQDVP Sbjct: 181 PTRELVVNAVTLFGNLQSFMKQELDQAVATQALWHTLRGRLRDVLCTPAHRLLQDSQDVP 240 Query: 241 VTVAPLRAERVLLFDDALVLLQGHNVHTFDLKLVWVDPGQDGCTFHLLTPEEEFSFCAKD 300 VTVAPLRAERVLLFDDALVLLQGHNVHTFDLKLVWVDPGQDGCTFHLLTPEEEFSFCAKD Sbjct: 241 VTVAPLRAERVLLFDDALVLLQGHNVHTFDLKLVWVDPGQDGCTFHLLTPEEEFSFCAKD 300 Query: 301 SQGQAVWQWKVTWAVHQALHGKKDFPVLGAGLEPSQPPDCRCAEYTFQAEGRLCQATYEG 360 SQGQAVWQWKVTWAVHQALHGKKDFPVLGAGLEPSQPPDCRCAEYTFQAEGRLCQATYEG Sbjct: 301 SQGQAVWQWKVTWAVHQALHGKKDFPVLGAGLEPSQPPDCRCAEYTFQAEGRLCQATYEG 360 Query: 361 EWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCG 420 EWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCG Sbjct: 361 EWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCG 420 Query: 421 YGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRG 480 YGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRG Sbjct: 421 YGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRG 480 Query: 481 ERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRDLTLM 540 ERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRDLTLM Sbjct: 481 ERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRDLTLM 540 Query: 541 GKGKVTFPNGFTLEGSFGSGAGRGLHTQGVLDTAALPPDPSSTCKRQLGVGAFPVESRWQ 600 GKGKVTFPNGFTLEGSFGSGAGRGLHTQGVLDTAALPPDPSSTCKRQLGVGAFPVESRWQ Sbjct: 541 GKGKVTFPNGFTLEGSFGSGAGRGLHTQGVLDTAALPPDPSSTCKRQLGVGAFPVESRWQ 600 Query: 601 GVYSPFRDFVCAGCPRDLQEALLGFDVQSSRELRRSQDYLSCERTHPEDSVGSMEDILEE 660 GVYSPFRDFVCAGCPRDLQEALLGFDVQSSRELRRSQDYLSCERTHPEDSVGSMEDILEE Sbjct: 601 GVYSPFRDFVCAGCPRDLQEALLGFDVQSSRELRRSQDYLSCERTHPEDSVGSMEDILEE 660 Query: 661 LLQHREPKALQLYLRKALSNSLHPLGKLLRTLMLTFQATYAGVGANKHLQELAQEEVKQH 720 LLQHREPKALQLYLRKALSNSLHPLGKLLRTLMLTFQATYAGVGANKHLQELAQEEVKQH Sbjct: 661 LLQHREPKALQLYLRKALSNSLHPLGKLLRTLMLTFQATYAGVGANKHLQELAQEEVKQH 720 Query: 721 AQELWAAYRGLLRVALERKGQALEEDEDTETRDLQVHGLVLPLMLPSFYSELFTLYLLLH 780 AQELWAAYRGLLRVALERKGQALEEDEDTETRDLQVHGLVLPLMLPSFYSELFTLYLLLH Sbjct: 721 AQELWAAYRGLLRVALERKGQALEEDEDTETRDLQVHGLVLPLMLPSFYSELFTLYLLLH 780 Query: 781 EREDSFYSQGIANLSLFPDTQLLEFLDVQKHLWPLKDLTLTSNQRYSLVRDKCFLSATEC 840 EREDSFYSQGIANLSLFPDTQLLEFLDVQKHLWPLKDLTLTSNQRYSLVRDKCFLSATEC Sbjct: 781 EREDSFYSQGIANLSLFPDTQLLEFLDVQKHLWPLKDLTLTSNQRYSLVRDKCFLSATEC 840 Query: 841 LQKIMTTVDPREKLEVLERTYGEIEGTVSRVLGREYKLPMDDLLPLLIYVVSRARIQHLG 900 LQKIMTTVDPREKLEVLERTYGEIEGTVSRVLGREYKLPMDDLLPLLIYVVSRARIQHLG Sbjct: 841 LQKIMTTVDPREKLEVLERTYGEIEGTVSRVLGREYKLPMDDLLPLLIYVVSRARIQHLG 900 Query: 901 AEIHLIRDMMDPNHTGGLYDFLLTALESCYEHIQKEDMRLHRLPGHWHSRELW 953 AEIHLIRDMMDPNHTGGLYDFLLTALESCYEHIQKEDMRLHRLPGHWHSRELW Sbjct: 901 AEIHLIRDMMDPNHTGGLYDFLLTALESCYEHIQKEDMRLHRLPGHWHSRELW 953 >gi|33359217 ALS2 C-terminal like isoform 3 [Homo sapiens] Length = 300 Score = 603 bits (1556), Expect = e-172 Identities = 300/300 (100%), Positives = 300/300 (100%) Query: 654 MEDILEELLQHREPKALQLYLRKALSNSLHPLGKLLRTLMLTFQATYAGVGANKHLQELA 713 MEDILEELLQHREPKALQLYLRKALSNSLHPLGKLLRTLMLTFQATYAGVGANKHLQELA Sbjct: 1 MEDILEELLQHREPKALQLYLRKALSNSLHPLGKLLRTLMLTFQATYAGVGANKHLQELA 60 Query: 714 QEEVKQHAQELWAAYRGLLRVALERKGQALEEDEDTETRDLQVHGLVLPLMLPSFYSELF 773 QEEVKQHAQELWAAYRGLLRVALERKGQALEEDEDTETRDLQVHGLVLPLMLPSFYSELF Sbjct: 61 QEEVKQHAQELWAAYRGLLRVALERKGQALEEDEDTETRDLQVHGLVLPLMLPSFYSELF 120 Query: 774 TLYLLLHEREDSFYSQGIANLSLFPDTQLLEFLDVQKHLWPLKDLTLTSNQRYSLVRDKC 833 TLYLLLHEREDSFYSQGIANLSLFPDTQLLEFLDVQKHLWPLKDLTLTSNQRYSLVRDKC Sbjct: 121 TLYLLLHEREDSFYSQGIANLSLFPDTQLLEFLDVQKHLWPLKDLTLTSNQRYSLVRDKC 180 Query: 834 FLSATECLQKIMTTVDPREKLEVLERTYGEIEGTVSRVLGREYKLPMDDLLPLLIYVVSR 893 FLSATECLQKIMTTVDPREKLEVLERTYGEIEGTVSRVLGREYKLPMDDLLPLLIYVVSR Sbjct: 181 FLSATECLQKIMTTVDPREKLEVLERTYGEIEGTVSRVLGREYKLPMDDLLPLLIYVVSR 240 Query: 894 ARIQHLGAEIHLIRDMMDPNHTGGLYDFLLTALESCYEHIQKEDMRLHRLPGHWHSRELW 953 ARIQHLGAEIHLIRDMMDPNHTGGLYDFLLTALESCYEHIQKEDMRLHRLPGHWHSRELW Sbjct: 241 ARIQHLGAEIHLIRDMMDPNHTGGLYDFLLTALESCYEHIQKEDMRLHRLPGHWHSRELW 300 >gi|40316935 alsin isoform 1 [Homo sapiens] Length = 1657 Score = 508 bits (1309), Expect = e-144 Identities = 330/977 (33%), Positives = 508/977 (51%), Gaps = 65/977 (6%) Query: 9 LLRLEEVFSATLAHVNSLVLQPLLPAAPDPSDPWGRECLRLLQQLHKSSQQLWEVTEESL 68 L E F + L+ + S +L+PLL + ++LLQ++ +L + + Sbjct: 698 LATTERRFYSKLSDIKSQILRPLLSL----ENLGTTTTVQLLQEVASRFSKLCYLIGQHG 753 Query: 69 HSLQERLRYPDSTGLESLLLLRGADRVLQAHIEYIESYTSCMVVQAFQKAAKRRSEYWRG 128 SL L SL++L+ + L ++ EY S T+ +V+ FQ AK ++ Sbjct: 754 ASLSSFLHGVKEA--RSLVILKHSSLFLDSYTEYCTSITNFLVMGGFQLLAKPAIDFLNK 811 Query: 129 QRKALRQLLSGVSSEGSVGASLGQALHQPLAHHVQQYVLLLLSLGDTIGEHHPTRELVVN 188 ++ L+ L S V+ E + + L + Y +LL L P + + + Sbjct: 812 NQELLQDL-SEVNDENTQLMEILNTLFFLPIRRLHNYAKVLLKLATCFEVASPEYQKLQD 870 Query: 189 AVTLFGNLQSFMKQELDQAVATQALWHTLRGRLRDVLCTPAHRLLQDSQDVPVTVAPLRA 248 + + + L + ++ +A T W T G++ D L P RLL +S + +++ Sbjct: 871 SSSCYECLALHLGRKRKEAEYTLGFWKTFPGKMTDSLRKPERRLLCESSNRALSLQHAGR 930 Query: 249 ERV---LLFDDALVLLQGHNVHTFDLKLVWVDP------GQDGCTFHLLTPEEEFSFCAK 299 V +LF+DALV Q H F L +W +P G +G + TPEE+F+ + Sbjct: 931 FSVNWFILFNDALVHAQFSTHHVFPLATLWAEPLSEEAGGVNG--LKITTPEEQFTLISS 988 Query: 300 DSQGQAVWQWKVTWAVHQALHGKKDFPVLGAG--LEPSQPPDCRCAEYTFQAEGRLCQAT 357 Q + W ++ AV QAL G D P G+G ++ +PP R A+YTF + RL AT Sbjct: 989 TPQEKTKWLRAISQAVDQALRGMSDLPPYGSGSSVQRQEPPISRSAKYTFYKDPRLKDAT 1048 Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGS 417 Y+G W G+PHG+G LKWPDG+ + G F GLE G+G +P + +K D Y HW+EG Sbjct: 1049 YDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEGK 1108 Query: 418 MCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGP-QAPQPFRYTGHWERGQRSGYGIEED 476 MCG G+ Y++ EV++G FQ+ +RHG G+L SG + P + G W +++GYG+ +D Sbjct: 1109 MCGQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGVFDD 1168 Query: 477 GDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRD 536 RGE+Y+GMWQ G GV+VTQ G+ Y+G F +K +G G+LLSEDD++YEG F+ D Sbjct: 1169 ITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMMGNGVLLSEDDTIYEGEFSDD 1228 Query: 537 LTLMGKGKVTFPNGFTLEGSFGSGAGRGLHTQGVLDTAALPPDPSSTCK--RQLGVGAFP 594 TL GKG +T PNG +EG F G G+ G +L K R+LG A P Sbjct: 1229 WTLSGKGTLTMPNGDYIEGYFSGEWGSGIKITGTYFKPSLYESDKDRPKVFRKLGNLAVP 1288 Query: 595 VESRWQGVYSP-FRDFVCAGCPRDLQEALLGFD------VQSSRELRRSQDYLSCERTHP 647 + +W+ V+ +R C G + E +D S R+ R S + LS +T Sbjct: 1289 ADEKWKAVFDECWRQLGCEGPGQG--EVWKAWDNIAVALTTSRRQHRDSPEILSRSQTQT 1346 Query: 648 EDSVGSMEDILEELLQH------REPKALQLYLRKALSNSLHPLGKLLRTLMLTFQATYA 701 +S LE + QH + ++ YL KA LHPLG+L+ TL+ ++ TY Sbjct: 1347 LES-------LEFIPQHVGAFSVEKYDDIRKYLIKACDTPLHPLGRLVETLVAVYRMTYV 1399 Query: 702 GVGANKHLQELAQEEVKQHAQELWAAYRGLL--------------RVALERKGQAL-EED 746 GVGAN+ L + A +E+K + + ++ R L + ERK + D Sbjct: 1400 GVGANRRLLQEAVKEIKSYLKRIFQLVRFLFPELPEEGSTIPLSAPLPTERKSFCTGKSD 1459 Query: 747 EDTETRD----LQVHGLVLPLMLPSFYSELFTLYLLLHEREDSFYSQGIANLSLFPDTQL 802 +E+ + + GL+LP++LP Y LF LY L ++RE+ Y + + L+ PD L Sbjct: 1460 SRSESPEPGYVVTSSGLLLPVLLPRLYPPLFMLYALDNDREEDIYWECVLRLNKQPDIAL 1519 Query: 803 LEFLDVQKHLWPLKDLTLTSNQR-YSLVRDKCFLSATECLQKIMTTVDPREKLEVLERTY 861 L FL VQ+ WP L +++ +D CF SA ECLQ+I TT P +KL+V+++T+ Sbjct: 1520 LGFLGVQRKFWPATLSILGESKKVLPTTKDACFASAVECLQQISTTFTPSDKLKVIQQTF 1579 Query: 862 GEIEGTVSRVLGREYKLPMDDLLPLLIYVVSRARIQHLGAEIHLIRDMMDPNHTGGLYDF 921 EI +V L ++ MDDL P+ +YVV RARI++LG+E+HLI D+MDP G Sbjct: 1580 EEISQSVLASLHEDFLWSMDDLFPVFLYVVLRARIRNLGSEVHLIEDLMDPYLQHGEQGI 1639 Query: 922 LLTALESCYEHIQKEDM 938 + T L++CY IQ+E + Sbjct: 1640 MFTTLKACYYQIQREKL 1656 >gi|153792461 radial spoke head 10 homolog B2 [Homo sapiens] Length = 870 Score = 85.9 bits (211), Expect = 2e-16 Identities = 55/209 (26%), Positives = 89/209 (42%), Gaps = 33/209 (15%) Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQA---------------- 401 YEG++ + P G WPDG + G G+ +GFG+ Sbjct: 132 YEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGK 191 Query: 402 -----SEDKFDCYKCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQP 456 +++ Y+ W + G+GI Y + +Y+G +++ +RHG G + + Sbjct: 192 GSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEE- 250 Query: 457 FRYTGHWERGQRSGYGIE---------EDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQ 507 YTG WERG ++G+G YIG + G RHG G +G Y Sbjct: 251 --YTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYD 308 Query: 508 GTFQADKTVGPGILLSEDDSLYEGTFTRD 536 G + ++K G G L ++ +YEG F+ D Sbjct: 309 GEWVSNKKHGMGRLTFKNGRVYEGAFSND 337 Score = 74.3 bits (181), Expect = 5e-13 Identities = 49/170 (28%), Positives = 80/170 (47%), Gaps = 15/170 (8%) Query: 357 TYEGEWCRGRPHGKGTLKWPDGRN--HVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWR 414 +Y G WC G+ HGKG++ + + G++ Q ++ G+GIR + Y+ W Sbjct: 178 SYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGN-----IYEGQWE 232 Query: 415 EGSMCGYGICEY-STDEVYKGYFQEGLRHGFGV----LESGPQAPQPFR--YTGHWERGQ 467 + G G + +T+E Y G ++ G+++GFG L+ + P R Y G + G Sbjct: 233 DNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGY 292 Query: 468 RSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVG 517 R G G G Y G W + ++HG G + + G Y+G F D G Sbjct: 293 RHGRGKFYYAS-GAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAG 341 Score = 42.0 bits (97), Expect = 0.003 Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 1/84 (1%) Query: 481 ERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRDLTLM 540 E Y G G G G Q G Y+G F G G + D YEG F +++ M Sbjct: 84 ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVP-M 142 Query: 541 GKGKVTFPNGFTLEGSFGSGAGRG 564 G T+P+G EG +G G Sbjct: 143 NHGVYTWPDGSMYEGEVVNGMRNG 166 Score = 39.3 bits (90), Expect = 0.018 Identities = 24/73 (32%), Positives = 32/73 (43%), Gaps = 1/73 (1%) Query: 459 YTGHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGP 518 Y G RG G G G Y GM+ G HG G + G+ Y+G F + + Sbjct: 86 YEGEKVRGLYEGEGFAAF-QGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNH 144 Query: 519 GILLSEDDSLYEG 531 G+ D S+YEG Sbjct: 145 GVYTWPDGSMYEG 157 Score = 38.1 bits (87), Expect = 0.039 Identities = 32/113 (28%), Positives = 39/113 (34%), Gaps = 19/113 (16%) Query: 350 EGRLCQAT----YEGEWCRGRPHGKGTLKW----------PDGRNHVGNFCQGLEHGFGI 395 EGR+ T Y G W RG +G GT W P ++G F G HG G Sbjct: 239 EGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGK 298 Query: 396 RLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLE 448 + Y W G G + VY+G F GF LE Sbjct: 299 FYYASGA-----MYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGFPDLE 346 >gi|157502187 radial spoke head 10 homolog B [Homo sapiens] Length = 870 Score = 85.9 bits (211), Expect = 2e-16 Identities = 55/209 (26%), Positives = 89/209 (42%), Gaps = 33/209 (15%) Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQA---------------- 401 YEG++ + P G WPDG + G G+ +GFG+ Sbjct: 132 YEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGK 191 Query: 402 -----SEDKFDCYKCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQP 456 +++ Y+ W + G+GI Y + +Y+G +++ +RHG G + + Sbjct: 192 GSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEE- 250 Query: 457 FRYTGHWERGQRSGYGIE---------EDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQ 507 YTG WERG ++G+G YIG + G RHG G +G Y Sbjct: 251 --YTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYD 308 Query: 508 GTFQADKTVGPGILLSEDDSLYEGTFTRD 536 G + ++K G G L ++ +YEG F+ D Sbjct: 309 GEWVSNKKHGMGRLTFKNGRVYEGAFSND 337 Score = 74.3 bits (181), Expect = 5e-13 Identities = 49/170 (28%), Positives = 80/170 (47%), Gaps = 15/170 (8%) Query: 357 TYEGEWCRGRPHGKGTLKWPDGRN--HVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWR 414 +Y G WC G+ HGKG++ + + G++ Q ++ G+GIR + Y+ W Sbjct: 178 SYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGN-----IYEGQWE 232 Query: 415 EGSMCGYGICEY-STDEVYKGYFQEGLRHGFGV----LESGPQAPQPFR--YTGHWERGQ 467 + G G + +T+E Y G ++ G+++GFG L+ + P R Y G + G Sbjct: 233 DNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGY 292 Query: 468 RSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVG 517 R G G G Y G W + ++HG G + + G Y+G F D G Sbjct: 293 RHGRGKFYYAS-GAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAG 341 Score = 42.0 bits (97), Expect = 0.003 Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 1/84 (1%) Query: 481 ERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRDLTLM 540 E Y G G G G Q G Y+G F G G + D YEG F +++ M Sbjct: 84 ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVP-M 142 Query: 541 GKGKVTFPNGFTLEGSFGSGAGRG 564 G T+P+G EG +G G Sbjct: 143 NHGVYTWPDGSMYEGEVVNGMRNG 166 Score = 39.3 bits (90), Expect = 0.018 Identities = 24/73 (32%), Positives = 32/73 (43%), Gaps = 1/73 (1%) Query: 459 YTGHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGP 518 Y G RG G G G Y GM+ G HG G + G+ Y+G F + + Sbjct: 86 YEGEKVRGLYEGEGFAAF-QGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNH 144 Query: 519 GILLSEDDSLYEG 531 G+ D S+YEG Sbjct: 145 GVYTWPDGSMYEG 157 Score = 38.1 bits (87), Expect = 0.039 Identities = 32/113 (28%), Positives = 39/113 (34%), Gaps = 19/113 (16%) Query: 350 EGRLCQAT----YEGEWCRGRPHGKGTLKW----------PDGRNHVGNFCQGLEHGFGI 395 EGR+ T Y G W RG +G GT W P ++G F G HG G Sbjct: 239 EGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGK 298 Query: 396 RLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLE 448 + Y W G G + VY+G F GF LE Sbjct: 299 FYYASGA-----MYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGFPDLE 346 >gi|13376267 MORN repeat containing 1 [Homo sapiens] Length = 497 Score = 85.1 bits (209), Expect = 3e-16 Identities = 62/203 (30%), Positives = 86/203 (42%), Gaps = 33/203 (16%) Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGS 417 YEGEW GR HG G L + DG + G F G G G R + D + + G Sbjct: 39 YEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSG----DTFSGQFVLGE 94 Query: 418 MCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDG 477 GYG+ EY Y+G G+R G G L ++ D Sbjct: 95 PQGYGVMEYKAGGCYEGEVSHGMREGHGFL-------------------------VDRD- 128 Query: 478 DRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRDL 537 G+ Y G + +RHGPG M+ Q G Y G + D+ G G+L D S Y+G + D+ Sbjct: 129 --GQVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDV 186 Query: 538 TLMGKGKVTFPNGFTLEGSFGSG 560 G G + +G T G + +G Sbjct: 187 -FSGLGSMAHCSGVTYYGLWING 208 Score = 62.8 bits (151), Expect = 1e-09 Identities = 43/141 (30%), Positives = 66/141 (46%), Gaps = 10/141 (7%) Query: 420 GYGICEYSTDEV-YKGYFQEGLRHGFGVL--ESGPQAPQPFRYTGHWERGQRSGYGIEED 476 GYG+ Y Y+G ++ G +HG G L + G Y G + G+ +G G Sbjct: 26 GYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSY------YEGAFVDGEITGEGRRHW 79 Query: 477 GDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRD 536 G+ + G + G+ G GVM +AG CY+G G G L+ D +Y+G+F D Sbjct: 80 AWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSF-HD 138 Query: 537 LTLMGKGKVTFPNGFTLEGSF 557 G G++ F NG +G + Sbjct: 139 NKRHGPGQMLFQNGDKYDGDW 159 Score = 55.1 bits (131), Expect = 3e-07 Identities = 41/154 (26%), Positives = 63/154 (40%), Gaps = 37/154 (24%) Query: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREG 416 T+ G++ G P G G +++ G + G G+ G G + R+G Sbjct: 85 TFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLV---------------DRDG 129 Query: 417 SMCGYGICEYSTDEVYKGYFQEGLRHGFG--VLESGPQAPQPFRYTGHWERGQRSGYGIE 474 +VY+G F + RHG G + ++G +Y G W R +R G+G+ Sbjct: 130 -------------QVYQGSFHDNKRHGPGQMLFQNGD------KYDGDWVRDRRQGHGVL 170 Query: 475 EDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQG 508 D G Y G W + G G M +GV Y G Sbjct: 171 RCAD-GSTYKGQWHSDVFSGLGSMAHCSGVTYYG 203 >gi|225690502 junctophilin 4 [Homo sapiens] Length = 628 Score = 73.2 bits (178), Expect = 1e-12 Identities = 52/143 (36%), Positives = 66/143 (46%), Gaps = 17/143 (11%) Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGF---GIRLLPQASEDKFDCYKCHWR 414 Y G W GR HG G P + G + HGF G+ P Y+ HW+ Sbjct: 15 YVGGWEAGRAHGYGVCTGPGAQ---GEYSGCWAHGFESLGVFTGPGGHS-----YQGHWQ 66 Query: 415 EGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIE 474 +G G G+ E + Y+G + GL+ GV ES RY G W+ G + GYG E Sbjct: 67 QGKREGLGV-ERKSRWTYRGEWLGGLKGRSGVWES----VSGLRYAGLWKDGFQDGYGTE 121 Query: 475 EDGDRGERYIGMWQAGQRHGPGV 497 D G Y G WQAG+RHG GV Sbjct: 122 TYSD-GGTYQGQWQAGKRHGYGV 143 Score = 66.2 bits (160), Expect = 1e-10 Identities = 46/150 (30%), Positives = 66/150 (44%), Gaps = 11/150 (7%) Query: 371 GTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDE 430 G + DG +VG + G HG+G+ P A + C W G G+ Sbjct: 5 GKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGC----WAHGFE-SLGVFTGPGGH 59 Query: 431 VYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGERYIGMWQAG 490 Y+G++Q+G R G GV + + Y G W G + G+ E G RY G+W+ G Sbjct: 60 SYQGHWQQGKREGLGV-----ERKSRWTYRGEWLGGLKGRSGVWESVS-GLRYAGLWKDG 113 Query: 491 QRHGPGVMVTQAGVCYQGTFQADKTVGPGI 520 + G G G YQG +QA K G G+ Sbjct: 114 FQDGYGTETYSDGGTYQGQWQAGKRHGYGV 143 Score = 56.6 bits (135), Expect = 1e-07 Identities = 41/132 (31%), Positives = 55/132 (41%), Gaps = 11/132 (8%) Query: 405 KFD-----CYKCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRY 459 KFD CY W G GYG+C T +G + HGF L P Y Sbjct: 6 KFDFDDGGCYVGGWEAGRAHGYGVC---TGPGAQGEYSGCWAHGFESLGVFT-GPGGHSY 61 Query: 460 TGHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPG 519 GHW++G+R G G+E Y G W G + GV + +G+ Y G ++ G G Sbjct: 62 QGHWQQGKREGLGVERKSRW--TYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYG 119 Query: 520 ILLSEDDSLYEG 531 D Y+G Sbjct: 120 TETYSDGGTYQG 131 Score = 49.3 bits (116), Expect = 2e-05 Identities = 31/121 (25%), Positives = 50/121 (41%), Gaps = 11/121 (9%) Query: 355 QATYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWR 414 Q Y G W G G P G ++ G++ QG G G+ + + Y+ W Sbjct: 36 QGEYSGCWAHGF-ESLGVFTGPGGHSYQGHWQQGKREGLGVERKSRWT------YRGEWL 88 Query: 415 EGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIE 474 G G+ E + Y G +++G + G+G Y G W+ G+R GYG+ Sbjct: 89 GGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGT----YQGQWQAGKRHGYGVR 144 Query: 475 E 475 + Sbjct: 145 Q 145 Score = 41.6 bits (96), Expect = 0.004 Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 1/61 (1%) Query: 459 YTGHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGP 518 Y G W +RSG+G+ + + G RY G W +RHG G G +G ++ ++ V Sbjct: 282 YAGEWRADRRSGFGVSQRSN-GLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHG 340 Query: 519 G 519 G Sbjct: 341 G 341 Score = 37.7 bits (86), Expect = 0.051 Identities = 24/61 (39%), Positives = 28/61 (45%), Gaps = 6/61 (9%) Query: 423 ICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYG--IEEDGDRG 480 + E S EVY G ++ R GFGV Q RY G W +R GYG DG R Sbjct: 273 LIEGSATEVYAGEWRADRRSGFGV----SQRSNGLRYEGEWLGNRRHGYGRTTRPDGSRE 328 Query: 481 E 481 E Sbjct: 329 E 329 Score = 37.7 bits (86), Expect = 0.051 Identities = 21/66 (31%), Positives = 32/66 (48%) Query: 476 DGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTR 535 +G E Y G W+A +R G GV G+ Y+G + ++ G G D S EG + R Sbjct: 275 EGSATEVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKR 334 Query: 536 DLTLMG 541 + + G Sbjct: 335 NRLVHG 340 Score = 35.8 bits (81), Expect = 0.20 Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%) Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQG-LEHGFGIR-LLPQA 401 YEGEW R HG G PDG G + + L HG +R LLP A Sbjct: 305 YEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGRVRSLLPLA 350 Score = 30.8 bits (68), Expect = 6.3 Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 4/75 (5%) Query: 331 GLEPSQPPDCRCAEYTFQAEGRLCQATYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLE 390 G E S PP A EG + Y GEW R G G + +G + G + Sbjct: 259 GSEASGPP---AAAPPALIEGSATEV-YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRR 314 Query: 391 HGFGIRLLPQASEDK 405 HG+G P S ++ Sbjct: 315 HGYGRTTRPDGSREE 329 >gi|225690500 junctophilin 4 [Homo sapiens] Length = 628 Score = 73.2 bits (178), Expect = 1e-12 Identities = 52/143 (36%), Positives = 66/143 (46%), Gaps = 17/143 (11%) Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGF---GIRLLPQASEDKFDCYKCHWR 414 Y G W GR HG G P + G + HGF G+ P Y+ HW+ Sbjct: 15 YVGGWEAGRAHGYGVCTGPGAQ---GEYSGCWAHGFESLGVFTGPGGHS-----YQGHWQ 66 Query: 415 EGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIE 474 +G G G+ E + Y+G + GL+ GV ES RY G W+ G + GYG E Sbjct: 67 QGKREGLGV-ERKSRWTYRGEWLGGLKGRSGVWES----VSGLRYAGLWKDGFQDGYGTE 121 Query: 475 EDGDRGERYIGMWQAGQRHGPGV 497 D G Y G WQAG+RHG GV Sbjct: 122 TYSD-GGTYQGQWQAGKRHGYGV 143 Score = 66.2 bits (160), Expect = 1e-10 Identities = 46/150 (30%), Positives = 66/150 (44%), Gaps = 11/150 (7%) Query: 371 GTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDE 430 G + DG +VG + G HG+G+ P A + C W G G+ Sbjct: 5 GKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGC----WAHGFE-SLGVFTGPGGH 59 Query: 431 VYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGERYIGMWQAG 490 Y+G++Q+G R G GV + + Y G W G + G+ E G RY G+W+ G Sbjct: 60 SYQGHWQQGKREGLGV-----ERKSRWTYRGEWLGGLKGRSGVWESVS-GLRYAGLWKDG 113 Query: 491 QRHGPGVMVTQAGVCYQGTFQADKTVGPGI 520 + G G G YQG +QA K G G+ Sbjct: 114 FQDGYGTETYSDGGTYQGQWQAGKRHGYGV 143 Score = 56.6 bits (135), Expect = 1e-07 Identities = 41/132 (31%), Positives = 55/132 (41%), Gaps = 11/132 (8%) Query: 405 KFD-----CYKCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRY 459 KFD CY W G GYG+C T +G + HGF L P Y Sbjct: 6 KFDFDDGGCYVGGWEAGRAHGYGVC---TGPGAQGEYSGCWAHGFESLGVFT-GPGGHSY 61 Query: 460 TGHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPG 519 GHW++G+R G G+E Y G W G + GV + +G+ Y G ++ G G Sbjct: 62 QGHWQQGKREGLGVERKSRW--TYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYG 119 Query: 520 ILLSEDDSLYEG 531 D Y+G Sbjct: 120 TETYSDGGTYQG 131 Score = 49.3 bits (116), Expect = 2e-05 Identities = 31/121 (25%), Positives = 50/121 (41%), Gaps = 11/121 (9%) Query: 355 QATYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWR 414 Q Y G W G G P G ++ G++ QG G G+ + + Y+ W Sbjct: 36 QGEYSGCWAHGF-ESLGVFTGPGGHSYQGHWQQGKREGLGVERKSRWT------YRGEWL 88 Query: 415 EGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIE 474 G G+ E + Y G +++G + G+G Y G W+ G+R GYG+ Sbjct: 89 GGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGT----YQGQWQAGKRHGYGVR 144 Query: 475 E 475 + Sbjct: 145 Q 145 Score = 41.6 bits (96), Expect = 0.004 Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 1/61 (1%) Query: 459 YTGHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGP 518 Y G W +RSG+G+ + + G RY G W +RHG G G +G ++ ++ V Sbjct: 282 YAGEWRADRRSGFGVSQRSN-GLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHG 340 Query: 519 G 519 G Sbjct: 341 G 341 Score = 37.7 bits (86), Expect = 0.051 Identities = 24/61 (39%), Positives = 28/61 (45%), Gaps = 6/61 (9%) Query: 423 ICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYG--IEEDGDRG 480 + E S EVY G ++ R GFGV Q RY G W +R GYG DG R Sbjct: 273 LIEGSATEVYAGEWRADRRSGFGV----SQRSNGLRYEGEWLGNRRHGYGRTTRPDGSRE 328 Query: 481 E 481 E Sbjct: 329 E 329 Score = 37.7 bits (86), Expect = 0.051 Identities = 21/66 (31%), Positives = 32/66 (48%) Query: 476 DGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTR 535 +G E Y G W+A +R G GV G+ Y+G + ++ G G D S EG + R Sbjct: 275 EGSATEVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKR 334 Query: 536 DLTLMG 541 + + G Sbjct: 335 NRLVHG 340 Score = 35.8 bits (81), Expect = 0.20 Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%) Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQG-LEHGFGIR-LLPQA 401 YEGEW R HG G PDG G + + L HG +R LLP A Sbjct: 305 YEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGRVRSLLPLA 350 Score = 30.8 bits (68), Expect = 6.3 Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 4/75 (5%) Query: 331 GLEPSQPPDCRCAEYTFQAEGRLCQATYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLE 390 G E S PP A EG + Y GEW R G G + +G + G + Sbjct: 259 GSEASGPP---AAAPPALIEGSATEV-YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRR 314 Query: 391 HGFGIRLLPQASEDK 405 HG+G P S ++ Sbjct: 315 HGYGRTTRPDGSREE 329 >gi|18254456 testis-specific gene A2 [Homo sapiens] Length = 309 Score = 71.6 bits (174), Expect = 3e-12 Identities = 47/163 (28%), Positives = 66/163 (40%), Gaps = 33/163 (20%) Query: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREG 416 TYEG + G+ HG+G K+ +G ++G + + +HG G + P S Sbjct: 43 TYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSR------------- 89 Query: 417 SMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEED 476 Y+G + LRHG GV YTG W QR G G Sbjct: 90 ---------------YEGEWANDLRHGHGVY----YYINNDTYTGEWFAHQRHGQGTYLY 130 Query: 477 GDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPG 519 + G +Y+G W GQ+ G ++ YQG F VGPG Sbjct: 131 AETGSKYVGTWVNGQQEGTAELI-HLNHRYQGKFLNKNPVGPG 172 Score = 49.7 bits (117), Expect = 1e-05 Identities = 35/115 (30%), Positives = 51/115 (44%), Gaps = 2/115 (1%) Query: 461 GHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGI 520 G E G+R G G G+ Y G ++ G+RHG G+ + G Y G + +K G G Sbjct: 23 GRNEAGERHGRG-RARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGT 81 Query: 521 LLSEDDSLYEGTFTRDLTLMGKGKVTFPNGFTLEGSFGSGAGRGLHTQGVLDTAA 575 + D S YEG + DL G G + N T G + + G T +T + Sbjct: 82 FIYPDGSRYEGEWANDLR-HGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGS 135 Score = 47.0 bits (110), Expect = 8e-05 Identities = 30/94 (31%), Positives = 48/94 (51%), Gaps = 3/94 (3%) Query: 473 IEEDG--DRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYE 530 +EE+G D GE G +AG+RHG G G Y+G+++ K G GI ++ + Y Sbjct: 9 LEEEGENDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYI 68 Query: 531 GTFTRDLTLMGKGKVTFPNGFTLEGSFGSGAGRG 564 G + R+ G+G +P+G EG + + G Sbjct: 69 GEYVRN-KKHGQGTFIYPDGSRYEGEWANDLRHG 101 >gi|21704281 junctophilin 2 isoform 1 [Homo sapiens] Length = 696 Score = 68.9 bits (167), Expect = 2e-11 Identities = 42/150 (28%), Positives = 62/150 (41%), Gaps = 10/150 (6%) Query: 371 GTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDE 430 G + DG + G + G HG G+ P+ + Y W G G+ + + Sbjct: 4 GRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGE----YSGSWNFGFEVA-GVYTWPSGN 58 Query: 431 VYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGERYIGMWQAG 490 ++GY+ +G RHG G+ G + Y G W G + YGI + G +Y G W G Sbjct: 59 TFEGYWSQGKRHGLGIETKGR-----WLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNG 113 Query: 491 QRHGPGVMVTQAGVCYQGTFQADKTVGPGI 520 + G G G YQG F G G+ Sbjct: 114 LQDGYGTETYADGGTYQGQFTNGMRHGYGV 143 Score = 57.0 bits (136), Expect = 8e-08 Identities = 32/95 (33%), Positives = 47/95 (49%), Gaps = 5/95 (5%) Query: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREG 416 T+EG W +G+ HG G ++ + G + G + +GIR S Y+ W G Sbjct: 59 TFEGYWSQGKRHGLG-IETKGRWLYKGEWTHGFKGRYGIR----QSSSSGAKYEGTWNNG 113 Query: 417 SMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGP 451 GYG Y+ Y+G F G+RHG+GV +S P Sbjct: 114 LQDGYGTETYADGGTYQGQFTNGMRHGYGVRQSVP 148 Score = 53.5 bits (127), Expect = 9e-07 Identities = 37/122 (30%), Positives = 48/122 (39%), Gaps = 12/122 (9%) Query: 355 QATYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWR 414 Q Y G W G G WP G G + QG HG GI + YK W Sbjct: 35 QGEYSGSWNFGFEVA-GVYTWPSGNTFEGYWSQGKRHGLGIETKGRW------LYKGEWT 87 Query: 415 EGSMCGYGICEYSTDEV-YKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGI 473 G YGI + S+ Y+G + GL+ G+G Y G + G R GYG+ Sbjct: 88 HGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYADGGT----YQGQFTNGMRHGYGV 143 Query: 474 EE 475 + Sbjct: 144 RQ 145 Score = 38.5 bits (88), Expect = 0.030 Identities = 19/53 (35%), Positives = 26/53 (49%), Gaps = 1/53 (1%) Query: 459 YTGHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQ 511 Y G W+ +RSG+G+ E G RY G W RHG G G +G ++ Sbjct: 291 YMGEWKNDKRSGFGVSERSS-GLRYEGEWLDNLRHGYGCTTLPDGHREEGKYR 342 Score = 34.7 bits (78), Expect = 0.44 Identities = 15/49 (30%), Positives = 22/49 (44%) Query: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDK 405 TY GEW + G G + G + G + L HG+G LP ++ Sbjct: 290 TYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREE 338 Score = 34.3 bits (77), Expect = 0.57 Identities = 22/57 (38%), Positives = 25/57 (43%), Gaps = 6/57 (10%) Query: 427 STDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIE--EDGDRGE 481 +T E Y G ++ R GFGV E RY G W R GYG DG R E Sbjct: 286 TTTETYMGEWKNDKRSGFGVSERS----SGLRYEGEWLDNLRHGYGCTTLPDGHREE 338 Score = 34.3 bits (77), Expect = 0.57 Identities = 13/39 (33%), Positives = 22/39 (56%) Query: 407 DCYKCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFG 445 + Y W+ G+G+ E S+ Y+G + + LRHG+G Sbjct: 289 ETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYG 327 Score = 30.8 bits (68), Expect = 6.3 Identities = 17/62 (27%), Positives = 28/62 (45%) Query: 476 DGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTR 535 D E Y+G W+ +R G GV +G+ Y+G + + G G D EG + Sbjct: 284 DATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRH 343 Query: 536 DL 537 ++ Sbjct: 344 NV 345 >gi|21704283 junctophilin 3 [Homo sapiens] Length = 748 Score = 67.8 bits (164), Expect = 5e-11 Identities = 41/150 (27%), Positives = 61/150 (40%), Gaps = 10/150 (6%) Query: 371 GTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDE 430 G + DG ++ G + G HG G+ P+ + Y W G G+ + + Sbjct: 5 GRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGE----YTGSWSHGFEV-LGVYTWPSGN 59 Query: 431 VYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGERYIGMWQAG 490 Y+G + +G RHG G+ G Y G W G + YG+ E G +Y G W G Sbjct: 60 TYQGTWAQGKRHGIGLESKGKWV-----YKGEWTHGFKGRYGVRECAGNGAKYEGTWSNG 114 Query: 491 QRHGPGVMVTQAGVCYQGTFQADKTVGPGI 520 + G G G YQG + G G+ Sbjct: 115 LQDGYGTETYSDGGTYQGQWVGGMRQGYGV 144 Score = 67.8 bits (164), Expect = 5e-11 Identities = 48/144 (33%), Positives = 62/144 (43%), Gaps = 16/144 (11%) Query: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGF---GIRLLPQASEDKFDCYKCHW 413 +Y G W G+ HG G P G+ G + HGF G+ P + Y+ W Sbjct: 14 SYCGGWEDGKAHGHGVCTGPKGQ---GEYTGSWSHGFEVLGVYTWPSG-----NTYQGTW 65 Query: 414 REGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGI 473 +G G G+ E VYKG + G + +GV E A +Y G W G + GYG Sbjct: 66 AQGKRHGIGL-ESKGKWVYKGEWTHGFKGRYGVREC---AGNGAKYEGTWSNGLQDGYGT 121 Query: 474 EEDGDRGERYIGMWQAGQRHGPGV 497 E D G Y G W G R G GV Sbjct: 122 ETYSD-GGTYQGQWVGGMRQGYGV 144 Score = 60.5 bits (145), Expect = 7e-09 Identities = 38/122 (31%), Positives = 52/122 (42%), Gaps = 12/122 (9%) Query: 355 QATYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWR 414 Q Y G W G G WP G + G + QG HG G+ S+ K+ YK W Sbjct: 36 QGEYTGSWSHGF-EVLGVYTWPSGNTYQGTWAQGKRHGIGLE-----SKGKW-VYKGEWT 88 Query: 415 EGSMCGYGICEYSTDEV-YKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGI 473 G YG+ E + + Y+G + GL+ G+G Y G W G R GYG+ Sbjct: 89 HGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGT----YQGQWVGGMRQGYGV 144 Query: 474 EE 475 + Sbjct: 145 RQ 146 Score = 48.5 bits (114), Expect = 3e-05 Identities = 24/72 (33%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Query: 446 VLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVC 505 V+E A Y G W+ +RSG+G+ + D G +Y G W + +RHG G M G Sbjct: 275 VIEDDIDATTTETYVGEWKNDKRSGFGVSQRSD-GLKYEGEWASNRRHGYGCMTFPDGTK 333 Query: 506 YQGTFQADKTVG 517 +G ++ + VG Sbjct: 334 EEGKYKQNILVG 345 Score = 43.9 bits (102), Expect = 7e-04 Identities = 55/254 (21%), Positives = 88/254 (34%), Gaps = 66/254 (25%) Query: 356 ATYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGL-------------------------- 389 A YEG W G G GT + DG + G + G+ Sbjct: 105 AKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSI 164 Query: 390 -----EHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDEVYK----GYFQEGL 440 EH G L P AS S G+ + +S E+ K G F+ L Sbjct: 165 NSLRSEHTNGTALHPDASPAVAGSPAV-----SRGGFVLVAHSDSEILKSKKKGLFRRSL 219 Query: 441 RHGFGVLESGPQAPQPFRYTGHWERGQRSGYG------------------------IEED 476 G + +S ++ + + +G IE+D Sbjct: 220 LSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDD 279 Query: 477 GDRG--ERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFT 534 D E Y+G W+ +R G GV G+ Y+G + +++ G G + D + EG + Sbjct: 280 IDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYK 339 Query: 535 RDLTLMGKGKVTFP 548 +++ + GK K P Sbjct: 340 QNILVGGKRKNLIP 353 >gi|21735575 junctophilin 1 [Homo sapiens] Length = 661 Score = 67.4 bits (163), Expect = 6e-11 Identities = 44/150 (29%), Positives = 62/150 (41%), Gaps = 10/150 (6%) Query: 371 GTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDE 430 G + DG + G + +G HG GI P+ + Y W G G + + Sbjct: 4 GRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGE----YSGSWSHGFEVVGGYT-WPSGN 58 Query: 431 VYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGERYIGMWQAG 490 Y+GY+ +G RHG GV G + Y G W G + YG+ + RY G W G Sbjct: 59 TYQGYWAQGKRHGLGVETKGK-----WMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNG 113 Query: 491 QRHGPGVMVTQAGVCYQGTFQADKTVGPGI 520 + G GV G YQG + G G+ Sbjct: 114 LQDGYGVETYGDGGTYQGQWAGGMRHGYGV 143 Score = 60.8 bits (146), Expect = 6e-09 Identities = 38/122 (31%), Positives = 53/122 (43%), Gaps = 12/122 (9%) Query: 355 QATYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWR 414 Q Y G W G G WP G + G + QG HG G+ ++ K+ Y+ W Sbjct: 35 QGEYSGSWSHGF-EVVGGYTWPSGNTYQGYWAQGKRHGLGVE-----TKGKW-MYRGEWS 87 Query: 415 EGSMCGYGICE-YSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGI 473 G YG+ + T Y+G + GL+ G+GV G Y G W G R GYG+ Sbjct: 88 HGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGT----YQGQWAGGMRHGYGV 143 Query: 474 EE 475 + Sbjct: 144 RQ 145 Score = 53.9 bits (128), Expect = 7e-07 Identities = 33/100 (33%), Positives = 48/100 (48%), Gaps = 15/100 (15%) Query: 357 TYEGEWCRGRPHGKGTL---KWPDGRNHVGNFCQGLEHGFGIR--LLPQASEDKFDCYKC 411 TY+G W +G+ HG G KW + G + G + +G+R L A Y+ Sbjct: 59 TYQGYWAQGKRHGLGVETKGKWM----YRGEWSHGFKGRYGVRQSLCTPAR------YEG 108 Query: 412 HWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGP 451 W G GYG+ Y Y+G + G+RHG+GV +S P Sbjct: 109 TWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVP 148 Score = 40.0 bits (92), Expect = 0.010 Identities = 22/73 (30%), Positives = 35/73 (47%) Query: 476 DGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTR 535 D E Y+G W+ +R+G GV G+ Y+G + +K G G + D S EG + Sbjct: 274 DATTTETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKN 333 Query: 536 DLTLMGKGKVTFP 548 ++ + G K P Sbjct: 334 NILVRGIRKQLIP 346 Score = 40.0 bits (92), Expect = 0.010 Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 1/53 (1%) Query: 459 YTGHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQ 511 Y G W+ +R+G+G+ E + G +Y G W +RHG G V G +G ++ Sbjct: 281 YMGEWKNDKRNGFGVSERSN-GMKYEGEWANNKRHGYGCTVFPDGSKEEGKYK 332 Score = 36.6 bits (83), Expect = 0.11 Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 6/57 (10%) Query: 427 STDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYG--IEEDGDRGE 481 +T E Y G ++ R+GFGV E +Y G W +R GYG + DG + E Sbjct: 276 TTTETYMGEWKNDKRNGFGVSERS----NGMKYEGEWANNKRHGYGCTVFPDGSKEE 328 Score = 35.8 bits (81), Expect = 0.20 Identities = 14/49 (28%), Positives = 25/49 (51%) Query: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDK 405 TY GEW + +G G + +G + G + HG+G + P S+++ Sbjct: 280 TYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEE 328 Score = 33.9 bits (76), Expect = 0.74 Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 1/43 (2%) Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQG-LEHGFGIRLLP 399 YEGEW + HG G +PDG G + L G +L+P Sbjct: 304 YEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIRKQLIP 346 Score = 31.2 bits (69), Expect = 4.8 Identities = 12/39 (30%), Positives = 19/39 (48%) Query: 407 DCYKCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFG 445 + Y W+ G+G+ E S Y+G + RHG+G Sbjct: 279 ETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYG 317 >gi|50355990 MORN repeat containing 3 [Homo sapiens] Length = 240 Score = 67.0 bits (162), Expect = 8e-11 Identities = 44/134 (32%), Positives = 66/134 (49%), Gaps = 4/134 (2%) Query: 407 DCYKCHWREGSMCGYGICEYSTD-EVYKGYFQEGLRHGFGVLESGPQAPQPFR--YTGHW 463 D Y W + G G + +Y+G ++ G R G+G L Q R Y+G W Sbjct: 36 DYYVGEWEDNVKHGKGTQVWKKKGAIYEGDWKFGKRDGYGTLSLPDQQTGKCRRVYSGWW 95 Query: 464 ERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLS 523 + ++SGYGI+ G + E Y G W QR G G M G Y+G ++ DK G G+L Sbjct: 96 KGDKKSGYGIQFFGPK-EYYEGDWCGSQRSGWGRMYYSNGDIYEGQWENDKPNGEGMLRL 154 Query: 524 EDDSLYEGTFTRDL 537 ++ + YEG + R + Sbjct: 155 KNGNRYEGCWERGM 168 Score = 62.0 bits (149), Expect = 3e-09 Identities = 44/141 (31%), Positives = 60/141 (42%), Gaps = 7/141 (4%) Query: 358 YEGEWCRGRPHGKGTLKW-PDGRNHVGNFCQGLEHGFGIRLLPQASEDKF-DCYKCHWRE 415 Y GEW HGKGT W G + G++ G G+G LP K Y W+ Sbjct: 38 YVGEWEDNVKHGKGTQVWKKKGAIYEGDWKFGKRDGYGTLSLPDQQTGKCRRVYSGWWKG 97 Query: 416 GSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEE 475 GYGI + E Y+G + R G+G + Y G WE + +G G+ Sbjct: 98 DKKSGYGIQFFGPKEYYEGDWCGSQRSGWGRM----YYSNGDIYEGQWENDKPNGEGMLR 153 Query: 476 DGDRGERYIGMWQAGQRHGPG 496 G RY G W+ G ++G G Sbjct: 154 -LKNGNRYEGCWERGMKNGAG 173 Score = 60.8 bits (146), Expect = 6e-09 Identities = 41/138 (29%), Positives = 63/138 (45%), Gaps = 15/138 (10%) Query: 356 ATYEGEWCRGRPHGKGTLKWPDG------RNHVGNFCQGLEHGFGIRLLPQASEDKFDCY 409 A YEG+W G+ G GTL PD R + G + + G+GI+ + Y Sbjct: 60 AIYEGDWKFGKRDGYGTLSLPDQQTGKCRRVYSGWWKGDKKSGYGIQFFGPK-----EYY 114 Query: 410 KCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRS 469 + W G+G YS ++Y+G ++ +G G+L + RY G WERG ++ Sbjct: 115 EGDWCGSQRSGWGRMYYSNGDIYEGQWENDKPNGEGML----RLKNGNRYEGCWERGMKN 170 Query: 470 GYGIEEDGDRGERYIGMW 487 G G D G+ + G W Sbjct: 171 GAGRFFHLDHGQLFEGFW 188 Score = 38.1 bits (87), Expect = 0.039 Identities = 33/133 (24%), Positives = 48/133 (36%), Gaps = 32/133 (24%) Query: 463 WER-GQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMV---------------------- 499 W+R QR+G + G+ Y+G W+ +HG G V Sbjct: 17 WDRKAQRNGLRSQVYAVNGDYYVGEWEDNVKHGKGTQVWKKKGAIYEGDWKFGKRDGYGT 76 Query: 500 -----TQAGVC---YQGTFQADKTVGPGILLSEDDSLYEGTFTRDLTLMGKGKVTFPNGF 551 Q G C Y G ++ DK G GI YEG + G G++ + NG Sbjct: 77 LSLPDQQTGKCRRVYSGWWKGDKKSGYGIQFFGPKEYYEGDWCGS-QRSGWGRMYYSNGD 135 Query: 552 TLEGSFGSGAGRG 564 EG + + G Sbjct: 136 IYEGQWENDKPNG 148 >gi|149999376 MORN repeat containing 4 [Homo sapiens] Length = 146 Score = 62.4 bits (150), Expect = 2e-09 Identities = 37/106 (34%), Positives = 55/106 (51%), Gaps = 5/106 (4%) Query: 422 GICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGE 481 G YS+ E Y+G ++EG RHGFG L Y GH+E G +G+G+ D G Sbjct: 6 GSFTYSSGEEYRGEWKEGRRHGFGQLMFADGG----TYLGHFENGLFNGFGVLTFSD-GS 60 Query: 482 RYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDS 527 RY G + G+ +G GV + + ++G F+ + G G+L D S Sbjct: 61 RYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGS 106 Score = 58.5 bits (140), Expect = 3e-08 Identities = 31/90 (34%), Positives = 46/90 (51%), Gaps = 5/90 (5%) Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGS 417 Y GEW GR HG G L + DG ++G+F GL +GFG+ S Y+ + +G Sbjct: 16 YRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSR-----YEGEFAQGK 70 Query: 418 MCGYGICEYSTDEVYKGYFQEGLRHGFGVL 447 G G+ + ++G F+ G GFG+L Sbjct: 71 FNGVGVFIRYDNMTFEGEFKNGRVDGFGLL 100 Score = 50.4 bits (119), Expect = 8e-06 Identities = 34/90 (37%), Positives = 43/90 (47%), Gaps = 3/90 (3%) Query: 480 GERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRDLTL 539 GE Y G W+ G+RHG G ++ G Y G F+ G G+L D S YEG F + Sbjct: 13 GEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQG-KF 71 Query: 540 MGKGKVTFPNGFTLEGSFGSGA--GRGLHT 567 G G + T EG F +G G GL T Sbjct: 72 NGVGVFIRYDNMTFEGEFKNGRVDGFGLLT 101 Score = 45.4 bits (106), Expect = 2e-04 Identities = 29/113 (25%), Positives = 48/113 (42%), Gaps = 11/113 (9%) Query: 370 KGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTD 429 KG+ + G + G + +G HGFG + Y H+ G G+G+ +S Sbjct: 5 KGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGG-----TYLGHFENGLFNGFGVLTFSDG 59 Query: 430 EVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGI--EEDGDRG 480 Y+G F +G +G GV + G ++ G+ G+G+ DG G Sbjct: 60 SRYEGEFAQGKFNGVGVFIRYDN----MTFEGEFKNGRVDGFGLLTFPDGSHG 108 Score = 32.3 bits (72), Expect = 2.2 Identities = 19/72 (26%), Positives = 36/72 (50%), Gaps = 9/72 (12%) Query: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFD--CYKCHWR 414 TY G + G +G G L + DG + G F QG +G G+ + ++D ++ ++ Sbjct: 38 TYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFI-------RYDNMTFEGEFK 90 Query: 415 EGSMCGYGICEY 426 G + G+G+ + Sbjct: 91 NGRVDGFGLLTF 102 Score = 32.0 bits (71), Expect = 2.8 Identities = 16/45 (35%), Positives = 21/45 (46%) Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQAS 402 YEGE+ +G+ +G G D G F G GFG+ P S Sbjct: 62 YEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGS 106 >gi|30520314 MORN repeat containing 4 [Homo sapiens] Length = 146 Score = 62.4 bits (150), Expect = 2e-09 Identities = 37/106 (34%), Positives = 55/106 (51%), Gaps = 5/106 (4%) Query: 422 GICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGE 481 G YS+ E Y+G ++EG RHGFG L Y GH+E G +G+G+ D G Sbjct: 6 GSFTYSSGEEYRGEWKEGRRHGFGQLMFADGG----TYLGHFENGLFNGFGVLTFSD-GS 60 Query: 482 RYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDS 527 RY G + G+ +G GV + + ++G F+ + G G+L D S Sbjct: 61 RYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGS 106 Score = 58.5 bits (140), Expect = 3e-08 Identities = 31/90 (34%), Positives = 46/90 (51%), Gaps = 5/90 (5%) Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGS 417 Y GEW GR HG G L + DG ++G+F GL +GFG+ S Y+ + +G Sbjct: 16 YRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSR-----YEGEFAQGK 70 Query: 418 MCGYGICEYSTDEVYKGYFQEGLRHGFGVL 447 G G+ + ++G F+ G GFG+L Sbjct: 71 FNGVGVFIRYDNMTFEGEFKNGRVDGFGLL 100 Score = 50.4 bits (119), Expect = 8e-06 Identities = 34/90 (37%), Positives = 43/90 (47%), Gaps = 3/90 (3%) Query: 480 GERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRDLTL 539 GE Y G W+ G+RHG G ++ G Y G F+ G G+L D S YEG F + Sbjct: 13 GEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQG-KF 71 Query: 540 MGKGKVTFPNGFTLEGSFGSGA--GRGLHT 567 G G + T EG F +G G GL T Sbjct: 72 NGVGVFIRYDNMTFEGEFKNGRVDGFGLLT 101 Score = 45.4 bits (106), Expect = 2e-04 Identities = 29/113 (25%), Positives = 48/113 (42%), Gaps = 11/113 (9%) Query: 370 KGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTD 429 KG+ + G + G + +G HGFG + Y H+ G G+G+ +S Sbjct: 5 KGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGG-----TYLGHFENGLFNGFGVLTFSDG 59 Query: 430 EVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGI--EEDGDRG 480 Y+G F +G +G GV + G ++ G+ G+G+ DG G Sbjct: 60 SRYEGEFAQGKFNGVGVFIRYDN----MTFEGEFKNGRVDGFGLLTFPDGSHG 108 Score = 32.3 bits (72), Expect = 2.2 Identities = 19/72 (26%), Positives = 36/72 (50%), Gaps = 9/72 (12%) Query: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFD--CYKCHWR 414 TY G + G +G G L + DG + G F QG +G G+ + ++D ++ ++ Sbjct: 38 TYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFI-------RYDNMTFEGEFK 90 Query: 415 EGSMCGYGICEY 426 G + G+G+ + Sbjct: 91 NGRVDGFGLLTF 102 Score = 32.0 bits (71), Expect = 2.8 Identities = 16/45 (35%), Positives = 21/45 (46%) Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQAS 402 YEGE+ +G+ +G G D G F G GFG+ P S Sbjct: 62 YEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGS 106 >gi|29893812 junctophilin 2 isoform 2 [Homo sapiens] Length = 129 Score = 61.6 bits (148), Expect = 3e-09 Identities = 37/136 (27%), Positives = 57/136 (41%), Gaps = 11/136 (8%) Query: 371 GTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDE 430 G + DG + G + G HG G+ P+ + Y W G G+ + + Sbjct: 4 GRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGE----YSGSWNFGFEVA-GVYTWPSGN 58 Query: 431 VYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGERYIGMWQAG 490 ++GY+ +G RHG G+ G + Y G W G + YGI + G +Y G W G Sbjct: 59 TFEGYWSQGKRHGLGIETKGR-----WLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNG 113 Query: 491 QRHGPGV-MVTQAGVC 505 + G G G+C Sbjct: 114 LQDGYGTETYADGGMC 129 Score = 33.1 bits (74), Expect = 1.3 Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 5/71 (7%) Query: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREG 416 T+EG W +G+ HG G ++ + G + G + +GIR S Y+ W G Sbjct: 59 TFEGYWSQGKRHGLG-IETKGRWLYKGEWTHGFKGRYGIR----QSSSSGAKYEGTWNNG 113 Query: 417 SMCGYGICEYS 427 GYG Y+ Sbjct: 114 LQDGYGTETYA 124 >gi|75750529 ankyrin repeat and MYND domain containing 1 isoform 1 [Homo sapiens] Length = 941 Score = 43.1 bits (100), Expect = 0.001 Identities = 35/110 (31%), Positives = 47/110 (42%), Gaps = 10/110 (9%) Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGS 417 Y+GE+ G G WP G ++ G F + HG G + P S Y H RE Sbjct: 2 YQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSH-RE-- 58 Query: 418 MCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQ 467 GYG Y +++G ++ R G GV E+ P Q G W R Q Sbjct: 59 --GYGTM-YMKTRLFQGLYKADQRFGPGV-ETYPDGSQD---VGLWFREQ 101 Score = 40.0 bits (92), Expect = 0.010 Identities = 34/123 (27%), Positives = 54/123 (43%), Gaps = 8/123 (6%) Query: 431 VYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGERYIGMWQAG 490 +Y+G F ++ G+G P Y G + R G G D G + G + Sbjct: 1 MYQGEFGLNMKLGYGKFSW----PTGESYHGQFYRDHCHGLGTYMWPD-GSSFTGTFYLS 55 Query: 491 QRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRDLTLMGKGKVTFPNG 550 R G G M + + +QG ++AD+ GPG+ D S G + R+ + K P+G Sbjct: 56 HREGYGTMYMKTRL-FQGLYKADQRFGPGVETYPDGSQDVGLWFREQLI--KLCTQIPSG 112 Query: 551 FTL 553 F+L Sbjct: 113 FSL 115 Score = 37.7 bits (86), Expect = 0.051 Identities = 15/38 (39%), Positives = 20/38 (52%) Query: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFG 394 +Y G++ R HG GT WPDG + G F G+G Sbjct: 24 SYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGYG 61 >gi|40353729 Ras and Rab interactor 3 [Homo sapiens] Length = 985 Score = 40.8 bits (94), Expect = 0.006 Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 3/89 (3%) Query: 850 PREKLEVLERTYGEIEGTVSRVLGREYK-LPMDDLLPLLIYVVSRARIQHLGAEIHLIRD 908 P +K+ +L +T I +++ LG K DD LP+L+YV++R+ + + + + + Sbjct: 755 PEKKISILLKTCKLIYDSMA--LGNPGKPYGADDFLPVLMYVLARSNLTEMLLNVEYMME 812 Query: 909 MMDPNHTGGLYDFLLTALESCYEHIQKED 937 +MDP G + LT EHI+ D Sbjct: 813 LMDPALQLGEGSYYLTTTYGALEHIKSYD 841 >gi|75750531 ankyrin repeat and MYND domain containing 1 isoform 2 [Homo sapiens] Length = 717 Score = 37.7 bits (86), Expect = 0.051 Identities = 15/38 (39%), Positives = 20/38 (52%) Query: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFG 394 +Y G++ R HG GT WPDG + G F G+G Sbjct: 113 SYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGYG 150 Score = 35.4 bits (80), Expect = 0.26 Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 1/59 (1%) Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREG 416 Y+GE+ G G WP G ++ G F + HG G + P S Y H REG Sbjct: 91 YQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSH-REG 148 Score = 33.1 bits (74), Expect = 1.3 Identities = 28/94 (29%), Positives = 37/94 (39%), Gaps = 8/94 (8%) Query: 464 ERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLS 523 E+ + G D E YI + Q GV Q G YQG F + +G G Sbjct: 56 EKEEEEAEGPLRAQDLRESYIQLVQ-------GVQEWQDGCMYQGEFGLNMKLGYGKFSW 108 Query: 524 EDDSLYEGTFTRDLTLMGKGKVTFPNGFTLEGSF 557 Y G F RD G G +P+G + G+F Sbjct: 109 PTGESYHGQFYRD-HCHGLGTYMWPDGSSFTGTF 141 Score = 31.2 bits (69), Expect = 4.8 Identities = 21/70 (30%), Positives = 26/70 (37%), Gaps = 14/70 (20%) Query: 413 WREGSM----------CGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGH 462 W++G M GYG + T E Y G F HG G P +TG Sbjct: 85 WQDGCMYQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTY----MWPDGSSFTGT 140 Query: 463 WERGQRSGYG 472 + R GYG Sbjct: 141 FYLSHREGYG 150 >gi|18466802 Ras and Rab interactor 2 [Homo sapiens] Length = 895 Score = 37.4 bits (85), Expect = 0.067 Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 5/95 (5%) Query: 834 FLSATECLQKIMTT---VDPREKLEVLERTYGEIEGTVSRVLGREYKLPMDDLLPLLIYV 890 F+ + K MT P +K+ +L R I + GR Y DD LP+L YV Sbjct: 648 FVDVEKIKVKFMTMQKMYSPEKKVMLLLRVCKLIYTVMENNSGRMYGA--DDFLPVLTYV 705 Query: 891 VSRARIQHLGAEIHLIRDMMDPNHTGGLYDFLLTA 925 +++ + L EI + +++DP+ G + LT+ Sbjct: 706 IAQCDMLELDTEIEYMMELLDPSLLHGEGGYYLTS 740 >gi|224282170 MORN repeat containing 2 [Homo sapiens] Length = 79 Score = 33.9 bits (76), Expect = 0.74 Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 4/55 (7%) Query: 418 MCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYG 472 M G+G E+ + VY+G F++ + HG G P +YTG++ + G G Sbjct: 1 MNGFGRLEHFSGAVYEGQFKDNMFHGLGTY----TFPNGAKYTGNFNENRVEGEG 51 Score = 33.1 bits (74), Expect = 1.3 Identities = 15/39 (38%), Positives = 21/39 (53%) Query: 356 ATYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFG 394 A YEG++ HG GT +P+G + GNF + G G Sbjct: 13 AVYEGQFKDNMFHGLGTYTFPNGAKYTGNFNENRVEGEG 51 >gi|108860690 chromosome 16 open reading frame 7 [Homo sapiens] Length = 631 Score = 33.9 bits (76), Expect = 0.74 Identities = 16/54 (29%), Positives = 31/54 (57%) Query: 881 DDLLPLLIYVVSRARIQHLGAEIHLIRDMMDPNHTGGLYDFLLTALESCYEHIQ 934 DDLLP+L +VV R+ + L +E + + + + G + LT+L+S +++ Sbjct: 569 DDLLPILSFVVLRSGLPQLVSECAALEEFIHEGYLIGEEGYCLTSLQSALSYVE 622 >gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens] Length = 1197 Score = 32.7 bits (73), Expect = 1.7 Identities = 28/141 (19%), Positives = 62/141 (43%), Gaps = 13/141 (9%) Query: 618 LQEALLGFDVQSSRELRRSQDYLSCERTHPEDSVGSMEDILEELLQHREPKALQLYLRK- 676 L+ + + + REL+ +Q L C +T + S M++ + +E +A+ L L + Sbjct: 776 LENKMKNAEAERERELKDAQKKLDCAKTKADASSKKMKE------KQQEVEAITLELEEL 829 Query: 677 -----ALSNSLHPLGKLLRTLMLTFQATYAGVGANKHLQELAQEEVKQHAQELWAAYRGL 731 + L + + +++ + A V NK AQEEV + +E+ A + Sbjct: 830 KREHTSYKQQLEAVNEAIKSYESQIEVMAAEVAKNKESVNKAQEEVTKQ-KEVITAQDTV 888 Query: 732 LRVALERKGQALEEDEDTETR 752 ++ + E++ D++ + Sbjct: 889 IKAKYAEVAKHKEQNNDSQLK 909 >gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens] Length = 1197 Score = 32.7 bits (73), Expect = 1.7 Identities = 28/141 (19%), Positives = 62/141 (43%), Gaps = 13/141 (9%) Query: 618 LQEALLGFDVQSSRELRRSQDYLSCERTHPEDSVGSMEDILEELLQHREPKALQLYLRK- 676 L+ + + + REL+ +Q L C +T + S M++ + +E +A+ L L + Sbjct: 776 LENKMKNAEAERERELKDAQKKLDCAKTKADASSKKMKE------KQQEVEAITLELEEL 829 Query: 677 -----ALSNSLHPLGKLLRTLMLTFQATYAGVGANKHLQELAQEEVKQHAQELWAAYRGL 731 + L + + +++ + A V NK AQEEV + +E+ A + Sbjct: 830 KREHTSYKQQLEAVNEAIKSYESQIEVMAAEVAKNKESVNKAQEEVTKQ-KEVITAQDTV 888 Query: 732 LRVALERKGQALEEDEDTETR 752 ++ + E++ D++ + Sbjct: 889 IKAKYAEVAKHKEQNNDSQLK 909 >gi|110347420 structural maintenance of chromosomes 2 [Homo sapiens] Length = 1197 Score = 32.7 bits (73), Expect = 1.7 Identities = 28/141 (19%), Positives = 62/141 (43%), Gaps = 13/141 (9%) Query: 618 LQEALLGFDVQSSRELRRSQDYLSCERTHPEDSVGSMEDILEELLQHREPKALQLYLRK- 676 L+ + + + REL+ +Q L C +T + S M++ + +E +A+ L L + Sbjct: 776 LENKMKNAEAERERELKDAQKKLDCAKTKADASSKKMKE------KQQEVEAITLELEEL 829 Query: 677 -----ALSNSLHPLGKLLRTLMLTFQATYAGVGANKHLQELAQEEVKQHAQELWAAYRGL 731 + L + + +++ + A V NK AQEEV + +E+ A + Sbjct: 830 KREHTSYKQQLEAVNEAIKSYESQIEVMAAEVAKNKESVNKAQEEVTKQ-KEVITAQDTV 888 Query: 732 LRVALERKGQALEEDEDTETR 752 ++ + E++ D++ + Sbjct: 889 IKAKYAEVAKHKEQNNDSQLK 909 >gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] Length = 1411 Score = 32.3 bits (72), Expect = 2.2 Identities = 68/297 (22%), Positives = 113/297 (38%), Gaps = 50/297 (16%) Query: 633 LRRSQDYLSCERTHPEDSVGSMEDILEELLQHREPKALQLYLR-KALSNSLHPLGKLLRT 691 L++ QDY E H E+SV ++ L ++ QL R A SLH Sbjct: 312 LKKEQDYTKLEEKHNEESVSKKN--IQATLHQKDLDCQQLQSRLSASETSLH-------- 361 Query: 692 LMLTFQATYAGVGANKHLQELAQEEVK-QHAQELWAAYRGLLRVALERKGQALEEDEDTE 750 + + + G K +EL++ E K QH L+ ++ Q EE E Sbjct: 362 -RIHVELSEKGEATQKLKEELSEVETKYQH-----------LKAEFKQLQQQREEKEQ-- 407 Query: 751 TRDLQVHGLVLPLMLPSFYSELFTLYLLLHEREDSFYSQGIANLSLFPDTQLLEFLDVQK 810 HGL L + +S+L L E Q + D + + D+Q Sbjct: 408 ------HGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKE-QQVADLQL 460 Query: 811 HLWPLKD-----LTLTSNQRYSLVRDKCFLSATECLQKIMTTVDPREKLEVLERTYGEIE 865 L L++ +T ++ ++ L + K + LQ+ TT RE LE+ +I Sbjct: 461 KLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQ-STTAKLREAQNDLEQVLRQIG 519 Query: 866 GTVSRVLGREYKLPMD-DLLPLL------IYVVSRARIQHLGAEIHLIRDMMDPNHT 915 ++ E L + + LL +Y A+IQ E ++ + + NHT Sbjct: 520 DKDQKIQNLEALLQKSKENISLLEKEREDLY----AKIQAGEGETAVLNQLQEKNHT 572 >gi|223278407 MORN repeat containing 5 [Homo sapiens] Length = 161 Score = 32.0 bits (71), Expect = 2.8 Identities = 19/59 (32%), Positives = 23/59 (38%), Gaps = 5/59 (8%) Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREG 416 Y GE+ GR GK P +VG G+ HG G P S+ Y W G Sbjct: 8 YIGEYVDGRMEGKAKYILPTETIYVGEMKDGMFHGEGTLYFPSGSQ-----YDAIWENG 61 >gi|4506123 PRP18 pre-mRNA processing factor 18 homolog [Homo sapiens] Length = 342 Score = 32.0 bits (71), Expect = 2.8 Identities = 22/81 (27%), Positives = 39/81 (48%), Gaps = 11/81 (13%) Query: 643 ERTHPEDSVGSMEDILEELLQHREPKALQLYLRKALSNSLHPLGKLLRTLMLTFQATYAG 702 +R P D S+ DI++ +LQ KA YL+ A+ N+ P+G +T +A Sbjct: 239 KRNLPADIKESITDIIKFMLQREYVKANDAYLQMAIGNAPWPIG-------VTMVGIHAR 291 Query: 703 VGA----NKHLQELAQEEVKQ 719 G +KH+ + +E ++ Sbjct: 292 TGREKIFSKHVAHVLNDETQR 312 >gi|82659109 retinoblastoma-associated factor 600 [Homo sapiens] Length = 5183 Score = 32.0 bits (71), Expect = 2.8 Identities = 19/65 (29%), Positives = 31/65 (47%) Query: 646 HPEDSVGSMEDILEELLQHREPKALQLYLRKALSNSLHPLGKLLRTLMLTFQATYAGVGA 705 H + + G E ILEE LQ+ E + RKA+ G+L++ +M T + Sbjct: 1365 HADPNSGLDESILEECLQYLEKQLESSQARKAMEEFFSDSGELVQIMMATANENLSAKFC 1424 Query: 706 NKHLQ 710 N+ L+ Sbjct: 1425 NRVLK 1429 >gi|18034775 PHD finger protein 20 [Homo sapiens] Length = 1012 Score = 31.6 bits (70), Expect = 3.7 Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 6/63 (9%) Query: 386 CQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFG 445 CQ +HG + LL + +K+ CY C G G+ +Y D K + G HG Sbjct: 672 CQCWQHGVCMGLLEENVPEKYTCYVCQDPPGQRPGF---KYWYD---KEWLSRGHMHGLA 725 Query: 446 VLE 448 LE Sbjct: 726 FLE 728 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.137 0.427 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 39,897,362 Number of Sequences: 37866 Number of extensions: 1977815 Number of successful extensions: 5058 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 25 Number of HSP's successfully gapped in prelim test: 11 Number of HSP's that attempted gapping in prelim test: 4671 Number of HSP's gapped (non-prelim): 173 length of query: 953 length of database: 18,247,518 effective HSP length: 112 effective length of query: 841 effective length of database: 14,006,526 effective search space: 11779488366 effective search space used: 11779488366 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.