Guide to the Human Genome
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Search of human proteins with 33359215

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens]
         (953 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens]            1964   0.0  
gi|33359217 ALS2 C-terminal like isoform 3 [Homo sapiens]             603   e-172
gi|40316935 alsin isoform 1 [Homo sapiens]                            508   e-144
gi|153792461 radial spoke head 10 homolog B2 [Homo sapiens]            86   2e-16
gi|157502187 radial spoke head 10 homolog B [Homo sapiens]             86   2e-16
gi|13376267 MORN repeat containing 1 [Homo sapiens]                    85   3e-16
gi|225690502 junctophilin 4 [Homo sapiens]                             73   1e-12
gi|225690500 junctophilin 4 [Homo sapiens]                             73   1e-12
gi|18254456 testis-specific gene A2 [Homo sapiens]                     72   3e-12
gi|21704281 junctophilin 2 isoform 1 [Homo sapiens]                    69   2e-11
gi|21704283 junctophilin 3 [Homo sapiens]                              68   5e-11
gi|21735575 junctophilin 1 [Homo sapiens]                              67   6e-11
gi|50355990 MORN repeat containing 3 [Homo sapiens]                    67   8e-11
gi|149999376 MORN repeat containing 4 [Homo sapiens]                   62   2e-09
gi|30520314 MORN repeat containing 4 [Homo sapiens]                    62   2e-09
gi|29893812 junctophilin 2 isoform 2 [Homo sapiens]                    62   3e-09
gi|75750529 ankyrin repeat and MYND domain containing 1 isoform ...    43   0.001
gi|40353729 Ras and Rab interactor 3 [Homo sapiens]                    41   0.006
gi|75750531 ankyrin repeat and MYND domain containing 1 isoform ...    38   0.051
gi|18466802 Ras and Rab interactor 2 [Homo sapiens]                    37   0.067
gi|224282170 MORN repeat containing 2 [Homo sapiens]                   34   0.74 
gi|108860690 chromosome 16 open reading frame 7 [Homo sapiens]         34   0.74 
gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens]    33   1.7  
gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens]    33   1.7  
gi|110347420 structural maintenance of chromosomes 2 [Homo sapiens]    33   1.7  
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             32   2.2  
gi|223278407 MORN repeat containing 5 [Homo sapiens]                   32   2.8  
gi|4506123 PRP18 pre-mRNA processing factor 18 homolog [Homo sap...    32   2.8  
gi|82659109 retinoblastoma-associated factor 600 [Homo sapiens]        32   2.8  
gi|18034775 PHD finger protein 20 [Homo sapiens]                       32   3.7  

>gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens]
          Length = 953

 Score = 1964 bits (5088), Expect = 0.0
 Identities = 953/953 (100%), Positives = 953/953 (100%)

Query: 1   MCNPEEAALLRLEEVFSATLAHVNSLVLQPLLPAAPDPSDPWGRECLRLLQQLHKSSQQL 60
           MCNPEEAALLRLEEVFSATLAHVNSLVLQPLLPAAPDPSDPWGRECLRLLQQLHKSSQQL
Sbjct: 1   MCNPEEAALLRLEEVFSATLAHVNSLVLQPLLPAAPDPSDPWGRECLRLLQQLHKSSQQL 60

Query: 61  WEVTEESLHSLQERLRYPDSTGLESLLLLRGADRVLQAHIEYIESYTSCMVVQAFQKAAK 120
           WEVTEESLHSLQERLRYPDSTGLESLLLLRGADRVLQAHIEYIESYTSCMVVQAFQKAAK
Sbjct: 61  WEVTEESLHSLQERLRYPDSTGLESLLLLRGADRVLQAHIEYIESYTSCMVVQAFQKAAK 120

Query: 121 RRSEYWRGQRKALRQLLSGVSSEGSVGASLGQALHQPLAHHVQQYVLLLLSLGDTIGEHH 180
           RRSEYWRGQRKALRQLLSGVSSEGSVGASLGQALHQPLAHHVQQYVLLLLSLGDTIGEHH
Sbjct: 121 RRSEYWRGQRKALRQLLSGVSSEGSVGASLGQALHQPLAHHVQQYVLLLLSLGDTIGEHH 180

Query: 181 PTRELVVNAVTLFGNLQSFMKQELDQAVATQALWHTLRGRLRDVLCTPAHRLLQDSQDVP 240
           PTRELVVNAVTLFGNLQSFMKQELDQAVATQALWHTLRGRLRDVLCTPAHRLLQDSQDVP
Sbjct: 181 PTRELVVNAVTLFGNLQSFMKQELDQAVATQALWHTLRGRLRDVLCTPAHRLLQDSQDVP 240

Query: 241 VTVAPLRAERVLLFDDALVLLQGHNVHTFDLKLVWVDPGQDGCTFHLLTPEEEFSFCAKD 300
           VTVAPLRAERVLLFDDALVLLQGHNVHTFDLKLVWVDPGQDGCTFHLLTPEEEFSFCAKD
Sbjct: 241 VTVAPLRAERVLLFDDALVLLQGHNVHTFDLKLVWVDPGQDGCTFHLLTPEEEFSFCAKD 300

Query: 301 SQGQAVWQWKVTWAVHQALHGKKDFPVLGAGLEPSQPPDCRCAEYTFQAEGRLCQATYEG 360
           SQGQAVWQWKVTWAVHQALHGKKDFPVLGAGLEPSQPPDCRCAEYTFQAEGRLCQATYEG
Sbjct: 301 SQGQAVWQWKVTWAVHQALHGKKDFPVLGAGLEPSQPPDCRCAEYTFQAEGRLCQATYEG 360

Query: 361 EWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCG 420
           EWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCG
Sbjct: 361 EWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCG 420

Query: 421 YGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRG 480
           YGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRG
Sbjct: 421 YGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRG 480

Query: 481 ERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRDLTLM 540
           ERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRDLTLM
Sbjct: 481 ERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRDLTLM 540

Query: 541 GKGKVTFPNGFTLEGSFGSGAGRGLHTQGVLDTAALPPDPSSTCKRQLGVGAFPVESRWQ 600
           GKGKVTFPNGFTLEGSFGSGAGRGLHTQGVLDTAALPPDPSSTCKRQLGVGAFPVESRWQ
Sbjct: 541 GKGKVTFPNGFTLEGSFGSGAGRGLHTQGVLDTAALPPDPSSTCKRQLGVGAFPVESRWQ 600

Query: 601 GVYSPFRDFVCAGCPRDLQEALLGFDVQSSRELRRSQDYLSCERTHPEDSVGSMEDILEE 660
           GVYSPFRDFVCAGCPRDLQEALLGFDVQSSRELRRSQDYLSCERTHPEDSVGSMEDILEE
Sbjct: 601 GVYSPFRDFVCAGCPRDLQEALLGFDVQSSRELRRSQDYLSCERTHPEDSVGSMEDILEE 660

Query: 661 LLQHREPKALQLYLRKALSNSLHPLGKLLRTLMLTFQATYAGVGANKHLQELAQEEVKQH 720
           LLQHREPKALQLYLRKALSNSLHPLGKLLRTLMLTFQATYAGVGANKHLQELAQEEVKQH
Sbjct: 661 LLQHREPKALQLYLRKALSNSLHPLGKLLRTLMLTFQATYAGVGANKHLQELAQEEVKQH 720

Query: 721 AQELWAAYRGLLRVALERKGQALEEDEDTETRDLQVHGLVLPLMLPSFYSELFTLYLLLH 780
           AQELWAAYRGLLRVALERKGQALEEDEDTETRDLQVHGLVLPLMLPSFYSELFTLYLLLH
Sbjct: 721 AQELWAAYRGLLRVALERKGQALEEDEDTETRDLQVHGLVLPLMLPSFYSELFTLYLLLH 780

Query: 781 EREDSFYSQGIANLSLFPDTQLLEFLDVQKHLWPLKDLTLTSNQRYSLVRDKCFLSATEC 840
           EREDSFYSQGIANLSLFPDTQLLEFLDVQKHLWPLKDLTLTSNQRYSLVRDKCFLSATEC
Sbjct: 781 EREDSFYSQGIANLSLFPDTQLLEFLDVQKHLWPLKDLTLTSNQRYSLVRDKCFLSATEC 840

Query: 841 LQKIMTTVDPREKLEVLERTYGEIEGTVSRVLGREYKLPMDDLLPLLIYVVSRARIQHLG 900
           LQKIMTTVDPREKLEVLERTYGEIEGTVSRVLGREYKLPMDDLLPLLIYVVSRARIQHLG
Sbjct: 841 LQKIMTTVDPREKLEVLERTYGEIEGTVSRVLGREYKLPMDDLLPLLIYVVSRARIQHLG 900

Query: 901 AEIHLIRDMMDPNHTGGLYDFLLTALESCYEHIQKEDMRLHRLPGHWHSRELW 953
           AEIHLIRDMMDPNHTGGLYDFLLTALESCYEHIQKEDMRLHRLPGHWHSRELW
Sbjct: 901 AEIHLIRDMMDPNHTGGLYDFLLTALESCYEHIQKEDMRLHRLPGHWHSRELW 953


>gi|33359217 ALS2 C-terminal like isoform 3 [Homo sapiens]
          Length = 300

 Score =  603 bits (1556), Expect = e-172
 Identities = 300/300 (100%), Positives = 300/300 (100%)

Query: 654 MEDILEELLQHREPKALQLYLRKALSNSLHPLGKLLRTLMLTFQATYAGVGANKHLQELA 713
           MEDILEELLQHREPKALQLYLRKALSNSLHPLGKLLRTLMLTFQATYAGVGANKHLQELA
Sbjct: 1   MEDILEELLQHREPKALQLYLRKALSNSLHPLGKLLRTLMLTFQATYAGVGANKHLQELA 60

Query: 714 QEEVKQHAQELWAAYRGLLRVALERKGQALEEDEDTETRDLQVHGLVLPLMLPSFYSELF 773
           QEEVKQHAQELWAAYRGLLRVALERKGQALEEDEDTETRDLQVHGLVLPLMLPSFYSELF
Sbjct: 61  QEEVKQHAQELWAAYRGLLRVALERKGQALEEDEDTETRDLQVHGLVLPLMLPSFYSELF 120

Query: 774 TLYLLLHEREDSFYSQGIANLSLFPDTQLLEFLDVQKHLWPLKDLTLTSNQRYSLVRDKC 833
           TLYLLLHEREDSFYSQGIANLSLFPDTQLLEFLDVQKHLWPLKDLTLTSNQRYSLVRDKC
Sbjct: 121 TLYLLLHEREDSFYSQGIANLSLFPDTQLLEFLDVQKHLWPLKDLTLTSNQRYSLVRDKC 180

Query: 834 FLSATECLQKIMTTVDPREKLEVLERTYGEIEGTVSRVLGREYKLPMDDLLPLLIYVVSR 893
           FLSATECLQKIMTTVDPREKLEVLERTYGEIEGTVSRVLGREYKLPMDDLLPLLIYVVSR
Sbjct: 181 FLSATECLQKIMTTVDPREKLEVLERTYGEIEGTVSRVLGREYKLPMDDLLPLLIYVVSR 240

Query: 894 ARIQHLGAEIHLIRDMMDPNHTGGLYDFLLTALESCYEHIQKEDMRLHRLPGHWHSRELW 953
           ARIQHLGAEIHLIRDMMDPNHTGGLYDFLLTALESCYEHIQKEDMRLHRLPGHWHSRELW
Sbjct: 241 ARIQHLGAEIHLIRDMMDPNHTGGLYDFLLTALESCYEHIQKEDMRLHRLPGHWHSRELW 300


>gi|40316935 alsin isoform 1 [Homo sapiens]
          Length = 1657

 Score =  508 bits (1309), Expect = e-144
 Identities = 330/977 (33%), Positives = 508/977 (51%), Gaps = 65/977 (6%)

Query: 9    LLRLEEVFSATLAHVNSLVLQPLLPAAPDPSDPWGRECLRLLQQLHKSSQQLWEVTEESL 68
            L   E  F + L+ + S +L+PLL       +      ++LLQ++     +L  +  +  
Sbjct: 698  LATTERRFYSKLSDIKSQILRPLLSL----ENLGTTTTVQLLQEVASRFSKLCYLIGQHG 753

Query: 69   HSLQERLRYPDSTGLESLLLLRGADRVLQAHIEYIESYTSCMVVQAFQKAAKRRSEYWRG 128
             SL   L         SL++L+ +   L ++ EY  S T+ +V+  FQ  AK   ++   
Sbjct: 754  ASLSSFLHGVKEA--RSLVILKHSSLFLDSYTEYCTSITNFLVMGGFQLLAKPAIDFLNK 811

Query: 129  QRKALRQLLSGVSSEGSVGASLGQALHQPLAHHVQQYVLLLLSLGDTIGEHHPTRELVVN 188
             ++ L+ L S V+ E +    +   L       +  Y  +LL L        P  + + +
Sbjct: 812  NQELLQDL-SEVNDENTQLMEILNTLFFLPIRRLHNYAKVLLKLATCFEVASPEYQKLQD 870

Query: 189  AVTLFGNLQSFMKQELDQAVATQALWHTLRGRLRDVLCTPAHRLLQDSQDVPVTVAPLRA 248
            + + +  L   + ++  +A  T   W T  G++ D L  P  RLL +S +  +++     
Sbjct: 871  SSSCYECLALHLGRKRKEAEYTLGFWKTFPGKMTDSLRKPERRLLCESSNRALSLQHAGR 930

Query: 249  ERV---LLFDDALVLLQGHNVHTFDLKLVWVDP------GQDGCTFHLLTPEEEFSFCAK 299
              V   +LF+DALV  Q    H F L  +W +P      G +G    + TPEE+F+  + 
Sbjct: 931  FSVNWFILFNDALVHAQFSTHHVFPLATLWAEPLSEEAGGVNG--LKITTPEEQFTLISS 988

Query: 300  DSQGQAVWQWKVTWAVHQALHGKKDFPVLGAG--LEPSQPPDCRCAEYTFQAEGRLCQAT 357
              Q +  W   ++ AV QAL G  D P  G+G  ++  +PP  R A+YTF  + RL  AT
Sbjct: 989  TPQEKTKWLRAISQAVDQALRGMSDLPPYGSGSSVQRQEPPISRSAKYTFYKDPRLKDAT 1048

Query: 358  YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGS 417
            Y+G W  G+PHG+G LKWPDG+ + G F  GLE G+G   +P  + +K D Y  HW+EG 
Sbjct: 1049 YDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEGK 1108

Query: 418  MCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGP-QAPQPFRYTGHWERGQRSGYGIEED 476
            MCG G+  Y++ EV++G FQ+ +RHG G+L SG   +  P  + G W   +++GYG+ +D
Sbjct: 1109 MCGQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGVFDD 1168

Query: 477  GDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRD 536
              RGE+Y+GMWQ     G GV+VTQ G+ Y+G F  +K +G G+LLSEDD++YEG F+ D
Sbjct: 1169 ITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMMGNGVLLSEDDTIYEGEFSDD 1228

Query: 537  LTLMGKGKVTFPNGFTLEGSFGSGAGRGLHTQGVLDTAALPPDPSSTCK--RQLGVGAFP 594
             TL GKG +T PNG  +EG F    G G+   G     +L        K  R+LG  A P
Sbjct: 1229 WTLSGKGTLTMPNGDYIEGYFSGEWGSGIKITGTYFKPSLYESDKDRPKVFRKLGNLAVP 1288

Query: 595  VESRWQGVYSP-FRDFVCAGCPRDLQEALLGFD------VQSSRELRRSQDYLSCERTHP 647
             + +W+ V+   +R   C G  +   E    +D        S R+ R S + LS  +T  
Sbjct: 1289 ADEKWKAVFDECWRQLGCEGPGQG--EVWKAWDNIAVALTTSRRQHRDSPEILSRSQTQT 1346

Query: 648  EDSVGSMEDILEELLQH------REPKALQLYLRKALSNSLHPLGKLLRTLMLTFQATYA 701
             +S       LE + QH       +   ++ YL KA    LHPLG+L+ TL+  ++ TY 
Sbjct: 1347 LES-------LEFIPQHVGAFSVEKYDDIRKYLIKACDTPLHPLGRLVETLVAVYRMTYV 1399

Query: 702  GVGANKHLQELAQEEVKQHAQELWAAYRGLL--------------RVALERKGQAL-EED 746
            GVGAN+ L + A +E+K + + ++   R L                +  ERK     + D
Sbjct: 1400 GVGANRRLLQEAVKEIKSYLKRIFQLVRFLFPELPEEGSTIPLSAPLPTERKSFCTGKSD 1459

Query: 747  EDTETRD----LQVHGLVLPLMLPSFYSELFTLYLLLHEREDSFYSQGIANLSLFPDTQL 802
              +E+ +    +   GL+LP++LP  Y  LF LY L ++RE+  Y + +  L+  PD  L
Sbjct: 1460 SRSESPEPGYVVTSSGLLLPVLLPRLYPPLFMLYALDNDREEDIYWECVLRLNKQPDIAL 1519

Query: 803  LEFLDVQKHLWPLKDLTLTSNQR-YSLVRDKCFLSATECLQKIMTTVDPREKLEVLERTY 861
            L FL VQ+  WP     L  +++     +D CF SA ECLQ+I TT  P +KL+V+++T+
Sbjct: 1520 LGFLGVQRKFWPATLSILGESKKVLPTTKDACFASAVECLQQISTTFTPSDKLKVIQQTF 1579

Query: 862  GEIEGTVSRVLGREYKLPMDDLLPLLIYVVSRARIQHLGAEIHLIRDMMDPNHTGGLYDF 921
             EI  +V   L  ++   MDDL P+ +YVV RARI++LG+E+HLI D+MDP    G    
Sbjct: 1580 EEISQSVLASLHEDFLWSMDDLFPVFLYVVLRARIRNLGSEVHLIEDLMDPYLQHGEQGI 1639

Query: 922  LLTALESCYEHIQKEDM 938
            + T L++CY  IQ+E +
Sbjct: 1640 MFTTLKACYYQIQREKL 1656


>gi|153792461 radial spoke head 10 homolog B2 [Homo sapiens]
          Length = 870

 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 55/209 (26%), Positives = 89/209 (42%), Gaps = 33/209 (15%)

Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQA---------------- 401
           YEG++ +  P   G   WPDG  + G    G+ +GFG+                      
Sbjct: 132 YEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGK 191

Query: 402 -----SEDKFDCYKCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQP 456
                +++    Y+  W +    G+GI  Y +  +Y+G +++ +RHG G +       + 
Sbjct: 192 GSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEE- 250

Query: 457 FRYTGHWERGQRSGYGIE---------EDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQ 507
             YTG WERG ++G+G                   YIG +  G RHG G     +G  Y 
Sbjct: 251 --YTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYD 308

Query: 508 GTFQADKTVGPGILLSEDDSLYEGTFTRD 536
           G + ++K  G G L  ++  +YEG F+ D
Sbjct: 309 GEWVSNKKHGMGRLTFKNGRVYEGAFSND 337



 Score = 74.3 bits (181), Expect = 5e-13
 Identities = 49/170 (28%), Positives = 80/170 (47%), Gaps = 15/170 (8%)

Query: 357 TYEGEWCRGRPHGKGTLKWPDGRN--HVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWR 414
           +Y G WC G+ HGKG++ +       + G++ Q ++ G+GIR     +      Y+  W 
Sbjct: 178 SYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGN-----IYEGQWE 232

Query: 415 EGSMCGYGICEY-STDEVYKGYFQEGLRHGFGV----LESGPQAPQPFR--YTGHWERGQ 467
           +    G G   + +T+E Y G ++ G+++GFG     L+    +  P R  Y G +  G 
Sbjct: 233 DNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGY 292

Query: 468 RSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVG 517
           R G G       G  Y G W + ++HG G +  + G  Y+G F  D   G
Sbjct: 293 RHGRGKFYYAS-GAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAG 341



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 1/84 (1%)

Query: 481 ERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRDLTLM 540
           E Y G    G   G G    Q G  Y+G F      G G  +  D   YEG F +++  M
Sbjct: 84  ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVP-M 142

Query: 541 GKGKVTFPNGFTLEGSFGSGAGRG 564
             G  T+P+G   EG   +G   G
Sbjct: 143 NHGVYTWPDGSMYEGEVVNGMRNG 166



 Score = 39.3 bits (90), Expect = 0.018
 Identities = 24/73 (32%), Positives = 32/73 (43%), Gaps = 1/73 (1%)

Query: 459 YTGHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGP 518
           Y G   RG   G G       G  Y GM+  G  HG G  +   G+ Y+G F  +  +  
Sbjct: 86  YEGEKVRGLYEGEGFAAF-QGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNH 144

Query: 519 GILLSEDDSLYEG 531
           G+    D S+YEG
Sbjct: 145 GVYTWPDGSMYEG 157



 Score = 38.1 bits (87), Expect = 0.039
 Identities = 32/113 (28%), Positives = 39/113 (34%), Gaps = 19/113 (16%)

Query: 350 EGRLCQAT----YEGEWCRGRPHGKGTLKW----------PDGRNHVGNFCQGLEHGFGI 395
           EGR+   T    Y G W RG  +G GT  W          P    ++G F  G  HG G 
Sbjct: 239 EGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGK 298

Query: 396 RLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLE 448
                 +      Y   W      G G   +    VY+G F      GF  LE
Sbjct: 299 FYYASGA-----MYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGFPDLE 346


>gi|157502187 radial spoke head 10 homolog B [Homo sapiens]
          Length = 870

 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 55/209 (26%), Positives = 89/209 (42%), Gaps = 33/209 (15%)

Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQA---------------- 401
           YEG++ +  P   G   WPDG  + G    G+ +GFG+                      
Sbjct: 132 YEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGK 191

Query: 402 -----SEDKFDCYKCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQP 456
                +++    Y+  W +    G+GI  Y +  +Y+G +++ +RHG G +       + 
Sbjct: 192 GSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEE- 250

Query: 457 FRYTGHWERGQRSGYGIE---------EDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQ 507
             YTG WERG ++G+G                   YIG +  G RHG G     +G  Y 
Sbjct: 251 --YTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYD 308

Query: 508 GTFQADKTVGPGILLSEDDSLYEGTFTRD 536
           G + ++K  G G L  ++  +YEG F+ D
Sbjct: 309 GEWVSNKKHGMGRLTFKNGRVYEGAFSND 337



 Score = 74.3 bits (181), Expect = 5e-13
 Identities = 49/170 (28%), Positives = 80/170 (47%), Gaps = 15/170 (8%)

Query: 357 TYEGEWCRGRPHGKGTLKWPDGRN--HVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWR 414
           +Y G WC G+ HGKG++ +       + G++ Q ++ G+GIR     +      Y+  W 
Sbjct: 178 SYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGN-----IYEGQWE 232

Query: 415 EGSMCGYGICEY-STDEVYKGYFQEGLRHGFGV----LESGPQAPQPFR--YTGHWERGQ 467
           +    G G   + +T+E Y G ++ G+++GFG     L+    +  P R  Y G +  G 
Sbjct: 233 DNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGY 292

Query: 468 RSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVG 517
           R G G       G  Y G W + ++HG G +  + G  Y+G F  D   G
Sbjct: 293 RHGRGKFYYAS-GAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAG 341



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 1/84 (1%)

Query: 481 ERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRDLTLM 540
           E Y G    G   G G    Q G  Y+G F      G G  +  D   YEG F +++  M
Sbjct: 84  ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVP-M 142

Query: 541 GKGKVTFPNGFTLEGSFGSGAGRG 564
             G  T+P+G   EG   +G   G
Sbjct: 143 NHGVYTWPDGSMYEGEVVNGMRNG 166



 Score = 39.3 bits (90), Expect = 0.018
 Identities = 24/73 (32%), Positives = 32/73 (43%), Gaps = 1/73 (1%)

Query: 459 YTGHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGP 518
           Y G   RG   G G       G  Y GM+  G  HG G  +   G+ Y+G F  +  +  
Sbjct: 86  YEGEKVRGLYEGEGFAAF-QGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNH 144

Query: 519 GILLSEDDSLYEG 531
           G+    D S+YEG
Sbjct: 145 GVYTWPDGSMYEG 157



 Score = 38.1 bits (87), Expect = 0.039
 Identities = 32/113 (28%), Positives = 39/113 (34%), Gaps = 19/113 (16%)

Query: 350 EGRLCQAT----YEGEWCRGRPHGKGTLKW----------PDGRNHVGNFCQGLEHGFGI 395
           EGR+   T    Y G W RG  +G GT  W          P    ++G F  G  HG G 
Sbjct: 239 EGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGK 298

Query: 396 RLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLE 448
                 +      Y   W      G G   +    VY+G F      GF  LE
Sbjct: 299 FYYASGA-----MYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGFPDLE 346


>gi|13376267 MORN repeat containing 1 [Homo sapiens]
          Length = 497

 Score = 85.1 bits (209), Expect = 3e-16
 Identities = 62/203 (30%), Positives = 86/203 (42%), Gaps = 33/203 (16%)

Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGS 417
           YEGEW  GR HG G L + DG  + G F  G   G G R    +     D +   +  G 
Sbjct: 39  YEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSG----DTFSGQFVLGE 94

Query: 418 MCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDG 477
             GYG+ EY     Y+G    G+R G G L                         ++ D 
Sbjct: 95  PQGYGVMEYKAGGCYEGEVSHGMREGHGFL-------------------------VDRD- 128

Query: 478 DRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRDL 537
             G+ Y G +   +RHGPG M+ Q G  Y G +  D+  G G+L   D S Y+G +  D+
Sbjct: 129 --GQVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDV 186

Query: 538 TLMGKGKVTFPNGFTLEGSFGSG 560
              G G +   +G T  G + +G
Sbjct: 187 -FSGLGSMAHCSGVTYYGLWING 208



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 43/141 (30%), Positives = 66/141 (46%), Gaps = 10/141 (7%)

Query: 420 GYGICEYSTDEV-YKGYFQEGLRHGFGVL--ESGPQAPQPFRYTGHWERGQRSGYGIEED 476
           GYG+  Y      Y+G ++ G +HG G L  + G        Y G +  G+ +G G    
Sbjct: 26  GYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSY------YEGAFVDGEITGEGRRHW 79

Query: 477 GDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRD 536
              G+ + G +  G+  G GVM  +AG CY+G        G G L+  D  +Y+G+F  D
Sbjct: 80  AWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSF-HD 138

Query: 537 LTLMGKGKVTFPNGFTLEGSF 557
               G G++ F NG   +G +
Sbjct: 139 NKRHGPGQMLFQNGDKYDGDW 159



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 41/154 (26%), Positives = 63/154 (40%), Gaps = 37/154 (24%)

Query: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREG 416
           T+ G++  G P G G +++  G  + G    G+  G G  +                R+G
Sbjct: 85  TFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLV---------------DRDG 129

Query: 417 SMCGYGICEYSTDEVYKGYFQEGLRHGFG--VLESGPQAPQPFRYTGHWERGQRSGYGIE 474
                        +VY+G F +  RHG G  + ++G       +Y G W R +R G+G+ 
Sbjct: 130 -------------QVYQGSFHDNKRHGPGQMLFQNGD------KYDGDWVRDRRQGHGVL 170

Query: 475 EDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQG 508
              D G  Y G W +    G G M   +GV Y G
Sbjct: 171 RCAD-GSTYKGQWHSDVFSGLGSMAHCSGVTYYG 203


>gi|225690502 junctophilin 4 [Homo sapiens]
          Length = 628

 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 52/143 (36%), Positives = 66/143 (46%), Gaps = 17/143 (11%)

Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGF---GIRLLPQASEDKFDCYKCHWR 414
           Y G W  GR HG G    P  +   G +     HGF   G+   P         Y+ HW+
Sbjct: 15  YVGGWEAGRAHGYGVCTGPGAQ---GEYSGCWAHGFESLGVFTGPGGHS-----YQGHWQ 66

Query: 415 EGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIE 474
           +G   G G+ E  +   Y+G +  GL+   GV ES        RY G W+ G + GYG E
Sbjct: 67  QGKREGLGV-ERKSRWTYRGEWLGGLKGRSGVWES----VSGLRYAGLWKDGFQDGYGTE 121

Query: 475 EDGDRGERYIGMWQAGQRHGPGV 497
              D G  Y G WQAG+RHG GV
Sbjct: 122 TYSD-GGTYQGQWQAGKRHGYGV 143



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 46/150 (30%), Positives = 66/150 (44%), Gaps = 11/150 (7%)

Query: 371 GTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDE 430
           G   + DG  +VG +  G  HG+G+   P A  +   C    W  G     G+       
Sbjct: 5   GKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGC----WAHGFE-SLGVFTGPGGH 59

Query: 431 VYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGERYIGMWQAG 490
            Y+G++Q+G R G GV     +    + Y G W  G +   G+ E    G RY G+W+ G
Sbjct: 60  SYQGHWQQGKREGLGV-----ERKSRWTYRGEWLGGLKGRSGVWESVS-GLRYAGLWKDG 113

Query: 491 QRHGPGVMVTQAGVCYQGTFQADKTVGPGI 520
            + G G      G  YQG +QA K  G G+
Sbjct: 114 FQDGYGTETYSDGGTYQGQWQAGKRHGYGV 143



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 41/132 (31%), Positives = 55/132 (41%), Gaps = 11/132 (8%)

Query: 405 KFD-----CYKCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRY 459
           KFD     CY   W  G   GYG+C   T    +G +     HGF  L      P    Y
Sbjct: 6   KFDFDDGGCYVGGWEAGRAHGYGVC---TGPGAQGEYSGCWAHGFESLGVFT-GPGGHSY 61

Query: 460 TGHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPG 519
            GHW++G+R G G+E        Y G W  G +   GV  + +G+ Y G ++     G G
Sbjct: 62  QGHWQQGKREGLGVERKSRW--TYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYG 119

Query: 520 ILLSEDDSLYEG 531
                D   Y+G
Sbjct: 120 TETYSDGGTYQG 131



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 31/121 (25%), Positives = 50/121 (41%), Gaps = 11/121 (9%)

Query: 355 QATYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWR 414
           Q  Y G W  G     G    P G ++ G++ QG   G G+    + +      Y+  W 
Sbjct: 36  QGEYSGCWAHGF-ESLGVFTGPGGHSYQGHWQQGKREGLGVERKSRWT------YRGEWL 88

Query: 415 EGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIE 474
            G     G+ E  +   Y G +++G + G+G             Y G W+ G+R GYG+ 
Sbjct: 89  GGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGT----YQGQWQAGKRHGYGVR 144

Query: 475 E 475
           +
Sbjct: 145 Q 145



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 1/61 (1%)

Query: 459 YTGHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGP 518
           Y G W   +RSG+G+ +  + G RY G W   +RHG G      G   +G ++ ++ V  
Sbjct: 282 YAGEWRADRRSGFGVSQRSN-GLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHG 340

Query: 519 G 519
           G
Sbjct: 341 G 341



 Score = 37.7 bits (86), Expect = 0.051
 Identities = 24/61 (39%), Positives = 28/61 (45%), Gaps = 6/61 (9%)

Query: 423 ICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYG--IEEDGDRG 480
           + E S  EVY G ++   R GFGV     Q     RY G W   +R GYG     DG R 
Sbjct: 273 LIEGSATEVYAGEWRADRRSGFGV----SQRSNGLRYEGEWLGNRRHGYGRTTRPDGSRE 328

Query: 481 E 481
           E
Sbjct: 329 E 329



 Score = 37.7 bits (86), Expect = 0.051
 Identities = 21/66 (31%), Positives = 32/66 (48%)

Query: 476 DGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTR 535
           +G   E Y G W+A +R G GV     G+ Y+G +  ++  G G     D S  EG + R
Sbjct: 275 EGSATEVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKR 334

Query: 536 DLTLMG 541
           +  + G
Sbjct: 335 NRLVHG 340



 Score = 35.8 bits (81), Expect = 0.20
 Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)

Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQG-LEHGFGIR-LLPQA 401
           YEGEW   R HG G    PDG    G + +  L HG  +R LLP A
Sbjct: 305 YEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGRVRSLLPLA 350



 Score = 30.8 bits (68), Expect = 6.3
 Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 4/75 (5%)

Query: 331 GLEPSQPPDCRCAEYTFQAEGRLCQATYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLE 390
           G E S PP    A      EG   +  Y GEW   R  G G  +  +G  + G +     
Sbjct: 259 GSEASGPP---AAAPPALIEGSATEV-YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRR 314

Query: 391 HGFGIRLLPQASEDK 405
           HG+G    P  S ++
Sbjct: 315 HGYGRTTRPDGSREE 329


>gi|225690500 junctophilin 4 [Homo sapiens]
          Length = 628

 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 52/143 (36%), Positives = 66/143 (46%), Gaps = 17/143 (11%)

Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGF---GIRLLPQASEDKFDCYKCHWR 414
           Y G W  GR HG G    P  +   G +     HGF   G+   P         Y+ HW+
Sbjct: 15  YVGGWEAGRAHGYGVCTGPGAQ---GEYSGCWAHGFESLGVFTGPGGHS-----YQGHWQ 66

Query: 415 EGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIE 474
           +G   G G+ E  +   Y+G +  GL+   GV ES        RY G W+ G + GYG E
Sbjct: 67  QGKREGLGV-ERKSRWTYRGEWLGGLKGRSGVWES----VSGLRYAGLWKDGFQDGYGTE 121

Query: 475 EDGDRGERYIGMWQAGQRHGPGV 497
              D G  Y G WQAG+RHG GV
Sbjct: 122 TYSD-GGTYQGQWQAGKRHGYGV 143



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 46/150 (30%), Positives = 66/150 (44%), Gaps = 11/150 (7%)

Query: 371 GTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDE 430
           G   + DG  +VG +  G  HG+G+   P A  +   C    W  G     G+       
Sbjct: 5   GKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGC----WAHGFE-SLGVFTGPGGH 59

Query: 431 VYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGERYIGMWQAG 490
            Y+G++Q+G R G GV     +    + Y G W  G +   G+ E    G RY G+W+ G
Sbjct: 60  SYQGHWQQGKREGLGV-----ERKSRWTYRGEWLGGLKGRSGVWESVS-GLRYAGLWKDG 113

Query: 491 QRHGPGVMVTQAGVCYQGTFQADKTVGPGI 520
            + G G      G  YQG +QA K  G G+
Sbjct: 114 FQDGYGTETYSDGGTYQGQWQAGKRHGYGV 143



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 41/132 (31%), Positives = 55/132 (41%), Gaps = 11/132 (8%)

Query: 405 KFD-----CYKCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRY 459
           KFD     CY   W  G   GYG+C   T    +G +     HGF  L      P    Y
Sbjct: 6   KFDFDDGGCYVGGWEAGRAHGYGVC---TGPGAQGEYSGCWAHGFESLGVFT-GPGGHSY 61

Query: 460 TGHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPG 519
            GHW++G+R G G+E        Y G W  G +   GV  + +G+ Y G ++     G G
Sbjct: 62  QGHWQQGKREGLGVERKSRW--TYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYG 119

Query: 520 ILLSEDDSLYEG 531
                D   Y+G
Sbjct: 120 TETYSDGGTYQG 131



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 31/121 (25%), Positives = 50/121 (41%), Gaps = 11/121 (9%)

Query: 355 QATYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWR 414
           Q  Y G W  G     G    P G ++ G++ QG   G G+    + +      Y+  W 
Sbjct: 36  QGEYSGCWAHGF-ESLGVFTGPGGHSYQGHWQQGKREGLGVERKSRWT------YRGEWL 88

Query: 415 EGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIE 474
            G     G+ E  +   Y G +++G + G+G             Y G W+ G+R GYG+ 
Sbjct: 89  GGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGT----YQGQWQAGKRHGYGVR 144

Query: 475 E 475
           +
Sbjct: 145 Q 145



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 1/61 (1%)

Query: 459 YTGHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGP 518
           Y G W   +RSG+G+ +  + G RY G W   +RHG G      G   +G ++ ++ V  
Sbjct: 282 YAGEWRADRRSGFGVSQRSN-GLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHG 340

Query: 519 G 519
           G
Sbjct: 341 G 341



 Score = 37.7 bits (86), Expect = 0.051
 Identities = 24/61 (39%), Positives = 28/61 (45%), Gaps = 6/61 (9%)

Query: 423 ICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYG--IEEDGDRG 480
           + E S  EVY G ++   R GFGV     Q     RY G W   +R GYG     DG R 
Sbjct: 273 LIEGSATEVYAGEWRADRRSGFGV----SQRSNGLRYEGEWLGNRRHGYGRTTRPDGSRE 328

Query: 481 E 481
           E
Sbjct: 329 E 329



 Score = 37.7 bits (86), Expect = 0.051
 Identities = 21/66 (31%), Positives = 32/66 (48%)

Query: 476 DGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTR 535
           +G   E Y G W+A +R G GV     G+ Y+G +  ++  G G     D S  EG + R
Sbjct: 275 EGSATEVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKR 334

Query: 536 DLTLMG 541
           +  + G
Sbjct: 335 NRLVHG 340



 Score = 35.8 bits (81), Expect = 0.20
 Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)

Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQG-LEHGFGIR-LLPQA 401
           YEGEW   R HG G    PDG    G + +  L HG  +R LLP A
Sbjct: 305 YEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGRVRSLLPLA 350



 Score = 30.8 bits (68), Expect = 6.3
 Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 4/75 (5%)

Query: 331 GLEPSQPPDCRCAEYTFQAEGRLCQATYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLE 390
           G E S PP    A      EG   +  Y GEW   R  G G  +  +G  + G +     
Sbjct: 259 GSEASGPP---AAAPPALIEGSATEV-YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRR 314

Query: 391 HGFGIRLLPQASEDK 405
           HG+G    P  S ++
Sbjct: 315 HGYGRTTRPDGSREE 329


>gi|18254456 testis-specific gene A2 [Homo sapiens]
          Length = 309

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 47/163 (28%), Positives = 66/163 (40%), Gaps = 33/163 (20%)

Query: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREG 416
           TYEG +  G+ HG+G  K+ +G  ++G + +  +HG G  + P  S              
Sbjct: 43  TYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSR------------- 89

Query: 417 SMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEED 476
                          Y+G +   LRHG GV            YTG W   QR G G    
Sbjct: 90  ---------------YEGEWANDLRHGHGVY----YYINNDTYTGEWFAHQRHGQGTYLY 130

Query: 477 GDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPG 519
            + G +Y+G W  GQ+ G   ++      YQG F     VGPG
Sbjct: 131 AETGSKYVGTWVNGQQEGTAELI-HLNHRYQGKFLNKNPVGPG 172



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 35/115 (30%), Positives = 51/115 (44%), Gaps = 2/115 (1%)

Query: 461 GHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGI 520
           G  E G+R G G       G+ Y G ++ G+RHG G+   + G  Y G +  +K  G G 
Sbjct: 23  GRNEAGERHGRG-RARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGT 81

Query: 521 LLSEDDSLYEGTFTRDLTLMGKGKVTFPNGFTLEGSFGSGAGRGLHTQGVLDTAA 575
            +  D S YEG +  DL   G G   + N  T  G + +    G  T    +T +
Sbjct: 82  FIYPDGSRYEGEWANDLR-HGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGS 135



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 30/94 (31%), Positives = 48/94 (51%), Gaps = 3/94 (3%)

Query: 473 IEEDG--DRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYE 530
           +EE+G  D GE   G  +AG+RHG G      G  Y+G+++  K  G GI   ++ + Y 
Sbjct: 9   LEEEGENDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYI 68

Query: 531 GTFTRDLTLMGKGKVTFPNGFTLEGSFGSGAGRG 564
           G + R+    G+G   +P+G   EG + +    G
Sbjct: 69  GEYVRN-KKHGQGTFIYPDGSRYEGEWANDLRHG 101


>gi|21704281 junctophilin 2 isoform 1 [Homo sapiens]
          Length = 696

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 42/150 (28%), Positives = 62/150 (41%), Gaps = 10/150 (6%)

Query: 371 GTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDE 430
           G   + DG  + G +  G  HG G+   P+   +    Y   W  G     G+  + +  
Sbjct: 4   GRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGE----YSGSWNFGFEVA-GVYTWPSGN 58

Query: 431 VYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGERYIGMWQAG 490
            ++GY+ +G RHG G+   G      + Y G W  G +  YGI +    G +Y G W  G
Sbjct: 59  TFEGYWSQGKRHGLGIETKGR-----WLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNG 113

Query: 491 QRHGPGVMVTQAGVCYQGTFQADKTVGPGI 520
            + G G      G  YQG F      G G+
Sbjct: 114 LQDGYGTETYADGGTYQGQFTNGMRHGYGV 143



 Score = 57.0 bits (136), Expect = 8e-08
 Identities = 32/95 (33%), Positives = 47/95 (49%), Gaps = 5/95 (5%)

Query: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREG 416
           T+EG W +G+ HG G ++      + G +  G +  +GIR     S      Y+  W  G
Sbjct: 59  TFEGYWSQGKRHGLG-IETKGRWLYKGEWTHGFKGRYGIR----QSSSSGAKYEGTWNNG 113

Query: 417 SMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGP 451
              GYG   Y+    Y+G F  G+RHG+GV +S P
Sbjct: 114 LQDGYGTETYADGGTYQGQFTNGMRHGYGVRQSVP 148



 Score = 53.5 bits (127), Expect = 9e-07
 Identities = 37/122 (30%), Positives = 48/122 (39%), Gaps = 12/122 (9%)

Query: 355 QATYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWR 414
           Q  Y G W  G     G   WP G    G + QG  HG GI    +        YK  W 
Sbjct: 35  QGEYSGSWNFGFEVA-GVYTWPSGNTFEGYWSQGKRHGLGIETKGRW------LYKGEWT 87

Query: 415 EGSMCGYGICEYSTDEV-YKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGI 473
            G    YGI + S+    Y+G +  GL+ G+G             Y G +  G R GYG+
Sbjct: 88  HGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYADGGT----YQGQFTNGMRHGYGV 143

Query: 474 EE 475
            +
Sbjct: 144 RQ 145



 Score = 38.5 bits (88), Expect = 0.030
 Identities = 19/53 (35%), Positives = 26/53 (49%), Gaps = 1/53 (1%)

Query: 459 YTGHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQ 511
           Y G W+  +RSG+G+ E    G RY G W    RHG G      G   +G ++
Sbjct: 291 YMGEWKNDKRSGFGVSERSS-GLRYEGEWLDNLRHGYGCTTLPDGHREEGKYR 342



 Score = 34.7 bits (78), Expect = 0.44
 Identities = 15/49 (30%), Positives = 22/49 (44%)

Query: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDK 405
           TY GEW   +  G G  +   G  + G +   L HG+G   LP    ++
Sbjct: 290 TYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREE 338



 Score = 34.3 bits (77), Expect = 0.57
 Identities = 22/57 (38%), Positives = 25/57 (43%), Gaps = 6/57 (10%)

Query: 427 STDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIE--EDGDRGE 481
           +T E Y G ++   R GFGV E         RY G W    R GYG     DG R E
Sbjct: 286 TTTETYMGEWKNDKRSGFGVSERS----SGLRYEGEWLDNLRHGYGCTTLPDGHREE 338



 Score = 34.3 bits (77), Expect = 0.57
 Identities = 13/39 (33%), Positives = 22/39 (56%)

Query: 407 DCYKCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFG 445
           + Y   W+     G+G+ E S+   Y+G + + LRHG+G
Sbjct: 289 ETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYG 327



 Score = 30.8 bits (68), Expect = 6.3
 Identities = 17/62 (27%), Positives = 28/62 (45%)

Query: 476 DGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTR 535
           D    E Y+G W+  +R G GV    +G+ Y+G +  +   G G     D    EG +  
Sbjct: 284 DATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRH 343

Query: 536 DL 537
           ++
Sbjct: 344 NV 345


>gi|21704283 junctophilin 3 [Homo sapiens]
          Length = 748

 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 41/150 (27%), Positives = 61/150 (40%), Gaps = 10/150 (6%)

Query: 371 GTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDE 430
           G   + DG ++ G +  G  HG G+   P+   +    Y   W  G     G+  + +  
Sbjct: 5   GRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGE----YTGSWSHGFEV-LGVYTWPSGN 59

Query: 431 VYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGERYIGMWQAG 490
            Y+G + +G RHG G+   G        Y G W  G +  YG+ E    G +Y G W  G
Sbjct: 60  TYQGTWAQGKRHGIGLESKGKWV-----YKGEWTHGFKGRYGVRECAGNGAKYEGTWSNG 114

Query: 491 QRHGPGVMVTQAGVCYQGTFQADKTVGPGI 520
            + G G      G  YQG +      G G+
Sbjct: 115 LQDGYGTETYSDGGTYQGQWVGGMRQGYGV 144



 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 48/144 (33%), Positives = 62/144 (43%), Gaps = 16/144 (11%)

Query: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGF---GIRLLPQASEDKFDCYKCHW 413
           +Y G W  G+ HG G    P G+   G +     HGF   G+   P       + Y+  W
Sbjct: 14  SYCGGWEDGKAHGHGVCTGPKGQ---GEYTGSWSHGFEVLGVYTWPSG-----NTYQGTW 65

Query: 414 REGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGI 473
            +G   G G+ E     VYKG +  G +  +GV E    A    +Y G W  G + GYG 
Sbjct: 66  AQGKRHGIGL-ESKGKWVYKGEWTHGFKGRYGVREC---AGNGAKYEGTWSNGLQDGYGT 121

Query: 474 EEDGDRGERYIGMWQAGQRHGPGV 497
           E   D G  Y G W  G R G GV
Sbjct: 122 ETYSD-GGTYQGQWVGGMRQGYGV 144



 Score = 60.5 bits (145), Expect = 7e-09
 Identities = 38/122 (31%), Positives = 52/122 (42%), Gaps = 12/122 (9%)

Query: 355 QATYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWR 414
           Q  Y G W  G     G   WP G  + G + QG  HG G+      S+ K+  YK  W 
Sbjct: 36  QGEYTGSWSHGF-EVLGVYTWPSGNTYQGTWAQGKRHGIGLE-----SKGKW-VYKGEWT 88

Query: 415 EGSMCGYGICEYSTDEV-YKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGI 473
            G    YG+ E + +   Y+G +  GL+ G+G             Y G W  G R GYG+
Sbjct: 89  HGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGT----YQGQWVGGMRQGYGV 144

Query: 474 EE 475
            +
Sbjct: 145 RQ 146



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 24/72 (33%), Positives = 37/72 (51%), Gaps = 1/72 (1%)

Query: 446 VLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVC 505
           V+E    A     Y G W+  +RSG+G+ +  D G +Y G W + +RHG G M    G  
Sbjct: 275 VIEDDIDATTTETYVGEWKNDKRSGFGVSQRSD-GLKYEGEWASNRRHGYGCMTFPDGTK 333

Query: 506 YQGTFQADKTVG 517
            +G ++ +  VG
Sbjct: 334 EEGKYKQNILVG 345



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 55/254 (21%), Positives = 88/254 (34%), Gaps = 66/254 (25%)

Query: 356 ATYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGL-------------------------- 389
           A YEG W  G   G GT  + DG  + G +  G+                          
Sbjct: 105 AKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSI 164

Query: 390 -----EHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDEVYK----GYFQEGL 440
                EH  G  L P AS              S  G+ +  +S  E+ K    G F+  L
Sbjct: 165 NSLRSEHTNGTALHPDASPAVAGSPAV-----SRGGFVLVAHSDSEILKSKKKGLFRRSL 219

Query: 441 RHGFGVLESGPQAPQPFRYTGHWERGQRSGYG------------------------IEED 476
             G  + +S  ++    + +        +G                          IE+D
Sbjct: 220 LSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDD 279

Query: 477 GDRG--ERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFT 534
            D    E Y+G W+  +R G GV     G+ Y+G + +++  G G +   D +  EG + 
Sbjct: 280 IDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYK 339

Query: 535 RDLTLMGKGKVTFP 548
           +++ + GK K   P
Sbjct: 340 QNILVGGKRKNLIP 353


>gi|21735575 junctophilin 1 [Homo sapiens]
          Length = 661

 Score = 67.4 bits (163), Expect = 6e-11
 Identities = 44/150 (29%), Positives = 62/150 (41%), Gaps = 10/150 (6%)

Query: 371 GTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDE 430
           G   + DG  + G + +G  HG GI   P+   +    Y   W  G     G   + +  
Sbjct: 4   GRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGE----YSGSWSHGFEVVGGYT-WPSGN 58

Query: 431 VYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGERYIGMWQAG 490
            Y+GY+ +G RHG GV   G      + Y G W  G +  YG+ +      RY G W  G
Sbjct: 59  TYQGYWAQGKRHGLGVETKGK-----WMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNG 113

Query: 491 QRHGPGVMVTQAGVCYQGTFQADKTVGPGI 520
            + G GV     G  YQG +      G G+
Sbjct: 114 LQDGYGVETYGDGGTYQGQWAGGMRHGYGV 143



 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 38/122 (31%), Positives = 53/122 (43%), Gaps = 12/122 (9%)

Query: 355 QATYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWR 414
           Q  Y G W  G     G   WP G  + G + QG  HG G+      ++ K+  Y+  W 
Sbjct: 35  QGEYSGSWSHGF-EVVGGYTWPSGNTYQGYWAQGKRHGLGVE-----TKGKW-MYRGEWS 87

Query: 415 EGSMCGYGICE-YSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGI 473
            G    YG+ +   T   Y+G +  GL+ G+GV   G        Y G W  G R GYG+
Sbjct: 88  HGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGT----YQGQWAGGMRHGYGV 143

Query: 474 EE 475
            +
Sbjct: 144 RQ 145



 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 33/100 (33%), Positives = 48/100 (48%), Gaps = 15/100 (15%)

Query: 357 TYEGEWCRGRPHGKGTL---KWPDGRNHVGNFCQGLEHGFGIR--LLPQASEDKFDCYKC 411
           TY+G W +G+ HG G     KW     + G +  G +  +G+R  L   A       Y+ 
Sbjct: 59  TYQGYWAQGKRHGLGVETKGKWM----YRGEWSHGFKGRYGVRQSLCTPAR------YEG 108

Query: 412 HWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGP 451
            W  G   GYG+  Y     Y+G +  G+RHG+GV +S P
Sbjct: 109 TWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVP 148



 Score = 40.0 bits (92), Expect = 0.010
 Identities = 22/73 (30%), Positives = 35/73 (47%)

Query: 476 DGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTR 535
           D    E Y+G W+  +R+G GV     G+ Y+G +  +K  G G  +  D S  EG +  
Sbjct: 274 DATTTETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKN 333

Query: 536 DLTLMGKGKVTFP 548
           ++ + G  K   P
Sbjct: 334 NILVRGIRKQLIP 346



 Score = 40.0 bits (92), Expect = 0.010
 Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 1/53 (1%)

Query: 459 YTGHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQ 511
           Y G W+  +R+G+G+ E  + G +Y G W   +RHG G  V   G   +G ++
Sbjct: 281 YMGEWKNDKRNGFGVSERSN-GMKYEGEWANNKRHGYGCTVFPDGSKEEGKYK 332



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 6/57 (10%)

Query: 427 STDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYG--IEEDGDRGE 481
           +T E Y G ++   R+GFGV E         +Y G W   +R GYG  +  DG + E
Sbjct: 276 TTTETYMGEWKNDKRNGFGVSERS----NGMKYEGEWANNKRHGYGCTVFPDGSKEE 328



 Score = 35.8 bits (81), Expect = 0.20
 Identities = 14/49 (28%), Positives = 25/49 (51%)

Query: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDK 405
           TY GEW   + +G G  +  +G  + G +     HG+G  + P  S+++
Sbjct: 280 TYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEE 328



 Score = 33.9 bits (76), Expect = 0.74
 Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 1/43 (2%)

Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQG-LEHGFGIRLLP 399
           YEGEW   + HG G   +PDG    G +    L  G   +L+P
Sbjct: 304 YEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIRKQLIP 346



 Score = 31.2 bits (69), Expect = 4.8
 Identities = 12/39 (30%), Positives = 19/39 (48%)

Query: 407 DCYKCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFG 445
           + Y   W+     G+G+ E S    Y+G +    RHG+G
Sbjct: 279 ETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYG 317


>gi|50355990 MORN repeat containing 3 [Homo sapiens]
          Length = 240

 Score = 67.0 bits (162), Expect = 8e-11
 Identities = 44/134 (32%), Positives = 66/134 (49%), Gaps = 4/134 (2%)

Query: 407 DCYKCHWREGSMCGYGICEYSTD-EVYKGYFQEGLRHGFGVLESGPQAPQPFR--YTGHW 463
           D Y   W +    G G   +     +Y+G ++ G R G+G L    Q     R  Y+G W
Sbjct: 36  DYYVGEWEDNVKHGKGTQVWKKKGAIYEGDWKFGKRDGYGTLSLPDQQTGKCRRVYSGWW 95

Query: 464 ERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLS 523
           +  ++SGYGI+  G + E Y G W   QR G G M    G  Y+G ++ DK  G G+L  
Sbjct: 96  KGDKKSGYGIQFFGPK-EYYEGDWCGSQRSGWGRMYYSNGDIYEGQWENDKPNGEGMLRL 154

Query: 524 EDDSLYEGTFTRDL 537
           ++ + YEG + R +
Sbjct: 155 KNGNRYEGCWERGM 168



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 44/141 (31%), Positives = 60/141 (42%), Gaps = 7/141 (4%)

Query: 358 YEGEWCRGRPHGKGTLKW-PDGRNHVGNFCQGLEHGFGIRLLPQASEDKF-DCYKCHWRE 415
           Y GEW     HGKGT  W   G  + G++  G   G+G   LP     K    Y   W+ 
Sbjct: 38  YVGEWEDNVKHGKGTQVWKKKGAIYEGDWKFGKRDGYGTLSLPDQQTGKCRRVYSGWWKG 97

Query: 416 GSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEE 475
               GYGI  +   E Y+G +    R G+G +           Y G WE  + +G G+  
Sbjct: 98  DKKSGYGIQFFGPKEYYEGDWCGSQRSGWGRM----YYSNGDIYEGQWENDKPNGEGMLR 153

Query: 476 DGDRGERYIGMWQAGQRHGPG 496
               G RY G W+ G ++G G
Sbjct: 154 -LKNGNRYEGCWERGMKNGAG 173



 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 41/138 (29%), Positives = 63/138 (45%), Gaps = 15/138 (10%)

Query: 356 ATYEGEWCRGRPHGKGTLKWPDG------RNHVGNFCQGLEHGFGIRLLPQASEDKFDCY 409
           A YEG+W  G+  G GTL  PD       R + G +    + G+GI+          + Y
Sbjct: 60  AIYEGDWKFGKRDGYGTLSLPDQQTGKCRRVYSGWWKGDKKSGYGIQFFGPK-----EYY 114

Query: 410 KCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRS 469
           +  W      G+G   YS  ++Y+G ++    +G G+L    +     RY G WERG ++
Sbjct: 115 EGDWCGSQRSGWGRMYYSNGDIYEGQWENDKPNGEGML----RLKNGNRYEGCWERGMKN 170

Query: 470 GYGIEEDGDRGERYIGMW 487
           G G     D G+ + G W
Sbjct: 171 GAGRFFHLDHGQLFEGFW 188



 Score = 38.1 bits (87), Expect = 0.039
 Identities = 33/133 (24%), Positives = 48/133 (36%), Gaps = 32/133 (24%)

Query: 463 WER-GQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMV---------------------- 499
           W+R  QR+G   +     G+ Y+G W+   +HG G  V                      
Sbjct: 17  WDRKAQRNGLRSQVYAVNGDYYVGEWEDNVKHGKGTQVWKKKGAIYEGDWKFGKRDGYGT 76

Query: 500 -----TQAGVC---YQGTFQADKTVGPGILLSEDDSLYEGTFTRDLTLMGKGKVTFPNGF 551
                 Q G C   Y G ++ DK  G GI        YEG +       G G++ + NG 
Sbjct: 77  LSLPDQQTGKCRRVYSGWWKGDKKSGYGIQFFGPKEYYEGDWCGS-QRSGWGRMYYSNGD 135

Query: 552 TLEGSFGSGAGRG 564
             EG + +    G
Sbjct: 136 IYEGQWENDKPNG 148


>gi|149999376 MORN repeat containing 4 [Homo sapiens]
          Length = 146

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 37/106 (34%), Positives = 55/106 (51%), Gaps = 5/106 (4%)

Query: 422 GICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGE 481
           G   YS+ E Y+G ++EG RHGFG L           Y GH+E G  +G+G+    D G 
Sbjct: 6   GSFTYSSGEEYRGEWKEGRRHGFGQLMFADGG----TYLGHFENGLFNGFGVLTFSD-GS 60

Query: 482 RYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDS 527
           RY G +  G+ +G GV +    + ++G F+  +  G G+L   D S
Sbjct: 61  RYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGS 106



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 31/90 (34%), Positives = 46/90 (51%), Gaps = 5/90 (5%)

Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGS 417
           Y GEW  GR HG G L + DG  ++G+F  GL +GFG+      S      Y+  + +G 
Sbjct: 16  YRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSR-----YEGEFAQGK 70

Query: 418 MCGYGICEYSTDEVYKGYFQEGLRHGFGVL 447
             G G+     +  ++G F+ G   GFG+L
Sbjct: 71  FNGVGVFIRYDNMTFEGEFKNGRVDGFGLL 100



 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 34/90 (37%), Positives = 43/90 (47%), Gaps = 3/90 (3%)

Query: 480 GERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRDLTL 539
           GE Y G W+ G+RHG G ++   G  Y G F+     G G+L   D S YEG F +    
Sbjct: 13  GEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQG-KF 71

Query: 540 MGKGKVTFPNGFTLEGSFGSGA--GRGLHT 567
            G G     +  T EG F +G   G GL T
Sbjct: 72  NGVGVFIRYDNMTFEGEFKNGRVDGFGLLT 101



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 29/113 (25%), Positives = 48/113 (42%), Gaps = 11/113 (9%)

Query: 370 KGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTD 429
           KG+  +  G  + G + +G  HGFG  +           Y  H+  G   G+G+  +S  
Sbjct: 5   KGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGG-----TYLGHFENGLFNGFGVLTFSDG 59

Query: 430 EVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGI--EEDGDRG 480
             Y+G F +G  +G GV            + G ++ G+  G+G+    DG  G
Sbjct: 60  SRYEGEFAQGKFNGVGVFIRYDN----MTFEGEFKNGRVDGFGLLTFPDGSHG 108



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 19/72 (26%), Positives = 36/72 (50%), Gaps = 9/72 (12%)

Query: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFD--CYKCHWR 414
           TY G +  G  +G G L + DG  + G F QG  +G G+ +       ++D   ++  ++
Sbjct: 38  TYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFI-------RYDNMTFEGEFK 90

Query: 415 EGSMCGYGICEY 426
            G + G+G+  +
Sbjct: 91  NGRVDGFGLLTF 102



 Score = 32.0 bits (71), Expect = 2.8
 Identities = 16/45 (35%), Positives = 21/45 (46%)

Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQAS 402
           YEGE+ +G+ +G G     D     G F  G   GFG+   P  S
Sbjct: 62  YEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGS 106


>gi|30520314 MORN repeat containing 4 [Homo sapiens]
          Length = 146

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 37/106 (34%), Positives = 55/106 (51%), Gaps = 5/106 (4%)

Query: 422 GICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGE 481
           G   YS+ E Y+G ++EG RHGFG L           Y GH+E G  +G+G+    D G 
Sbjct: 6   GSFTYSSGEEYRGEWKEGRRHGFGQLMFADGG----TYLGHFENGLFNGFGVLTFSD-GS 60

Query: 482 RYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDS 527
           RY G +  G+ +G GV +    + ++G F+  +  G G+L   D S
Sbjct: 61  RYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGS 106



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 31/90 (34%), Positives = 46/90 (51%), Gaps = 5/90 (5%)

Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGS 417
           Y GEW  GR HG G L + DG  ++G+F  GL +GFG+      S      Y+  + +G 
Sbjct: 16  YRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSR-----YEGEFAQGK 70

Query: 418 MCGYGICEYSTDEVYKGYFQEGLRHGFGVL 447
             G G+     +  ++G F+ G   GFG+L
Sbjct: 71  FNGVGVFIRYDNMTFEGEFKNGRVDGFGLL 100



 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 34/90 (37%), Positives = 43/90 (47%), Gaps = 3/90 (3%)

Query: 480 GERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRDLTL 539
           GE Y G W+ G+RHG G ++   G  Y G F+     G G+L   D S YEG F +    
Sbjct: 13  GEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQG-KF 71

Query: 540 MGKGKVTFPNGFTLEGSFGSGA--GRGLHT 567
            G G     +  T EG F +G   G GL T
Sbjct: 72  NGVGVFIRYDNMTFEGEFKNGRVDGFGLLT 101



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 29/113 (25%), Positives = 48/113 (42%), Gaps = 11/113 (9%)

Query: 370 KGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTD 429
           KG+  +  G  + G + +G  HGFG  +           Y  H+  G   G+G+  +S  
Sbjct: 5   KGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGG-----TYLGHFENGLFNGFGVLTFSDG 59

Query: 430 EVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGI--EEDGDRG 480
             Y+G F +G  +G GV            + G ++ G+  G+G+    DG  G
Sbjct: 60  SRYEGEFAQGKFNGVGVFIRYDN----MTFEGEFKNGRVDGFGLLTFPDGSHG 108



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 19/72 (26%), Positives = 36/72 (50%), Gaps = 9/72 (12%)

Query: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFD--CYKCHWR 414
           TY G +  G  +G G L + DG  + G F QG  +G G+ +       ++D   ++  ++
Sbjct: 38  TYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFI-------RYDNMTFEGEFK 90

Query: 415 EGSMCGYGICEY 426
            G + G+G+  +
Sbjct: 91  NGRVDGFGLLTF 102



 Score = 32.0 bits (71), Expect = 2.8
 Identities = 16/45 (35%), Positives = 21/45 (46%)

Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQAS 402
           YEGE+ +G+ +G G     D     G F  G   GFG+   P  S
Sbjct: 62  YEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGS 106


>gi|29893812 junctophilin 2 isoform 2 [Homo sapiens]
          Length = 129

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 37/136 (27%), Positives = 57/136 (41%), Gaps = 11/136 (8%)

Query: 371 GTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDE 430
           G   + DG  + G +  G  HG G+   P+   +    Y   W  G     G+  + +  
Sbjct: 4   GRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGE----YSGSWNFGFEVA-GVYTWPSGN 58

Query: 431 VYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGERYIGMWQAG 490
            ++GY+ +G RHG G+   G      + Y G W  G +  YGI +    G +Y G W  G
Sbjct: 59  TFEGYWSQGKRHGLGIETKGR-----WLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNG 113

Query: 491 QRHGPGV-MVTQAGVC 505
            + G G       G+C
Sbjct: 114 LQDGYGTETYADGGMC 129



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 5/71 (7%)

Query: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREG 416
           T+EG W +G+ HG G ++      + G +  G +  +GIR     S      Y+  W  G
Sbjct: 59  TFEGYWSQGKRHGLG-IETKGRWLYKGEWTHGFKGRYGIR----QSSSSGAKYEGTWNNG 113

Query: 417 SMCGYGICEYS 427
              GYG   Y+
Sbjct: 114 LQDGYGTETYA 124


>gi|75750529 ankyrin repeat and MYND domain containing 1 isoform 1
           [Homo sapiens]
          Length = 941

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 35/110 (31%), Positives = 47/110 (42%), Gaps = 10/110 (9%)

Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGS 417
           Y+GE+      G G   WP G ++ G F +   HG G  + P  S      Y  H RE  
Sbjct: 2   YQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSH-RE-- 58

Query: 418 MCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQ 467
             GYG   Y    +++G ++   R G GV E+ P   Q     G W R Q
Sbjct: 59  --GYGTM-YMKTRLFQGLYKADQRFGPGV-ETYPDGSQD---VGLWFREQ 101



 Score = 40.0 bits (92), Expect = 0.010
 Identities = 34/123 (27%), Positives = 54/123 (43%), Gaps = 8/123 (6%)

Query: 431 VYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGERYIGMWQAG 490
           +Y+G F   ++ G+G        P    Y G + R    G G     D G  + G +   
Sbjct: 1   MYQGEFGLNMKLGYGKFSW----PTGESYHGQFYRDHCHGLGTYMWPD-GSSFTGTFYLS 55

Query: 491 QRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRDLTLMGKGKVTFPNG 550
            R G G M  +  + +QG ++AD+  GPG+    D S   G + R+  +  K     P+G
Sbjct: 56  HREGYGTMYMKTRL-FQGLYKADQRFGPGVETYPDGSQDVGLWFREQLI--KLCTQIPSG 112

Query: 551 FTL 553
           F+L
Sbjct: 113 FSL 115



 Score = 37.7 bits (86), Expect = 0.051
 Identities = 15/38 (39%), Positives = 20/38 (52%)

Query: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFG 394
           +Y G++ R   HG GT  WPDG +  G F      G+G
Sbjct: 24  SYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGYG 61


>gi|40353729 Ras and Rab interactor 3 [Homo sapiens]
          Length = 985

 Score = 40.8 bits (94), Expect = 0.006
 Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 3/89 (3%)

Query: 850 PREKLEVLERTYGEIEGTVSRVLGREYK-LPMDDLLPLLIYVVSRARIQHLGAEIHLIRD 908
           P +K+ +L +T   I  +++  LG   K    DD LP+L+YV++R+ +  +   +  + +
Sbjct: 755 PEKKISILLKTCKLIYDSMA--LGNPGKPYGADDFLPVLMYVLARSNLTEMLLNVEYMME 812

Query: 909 MMDPNHTGGLYDFLLTALESCYEHIQKED 937
           +MDP    G   + LT      EHI+  D
Sbjct: 813 LMDPALQLGEGSYYLTTTYGALEHIKSYD 841


>gi|75750531 ankyrin repeat and MYND domain containing 1 isoform 2
           [Homo sapiens]
          Length = 717

 Score = 37.7 bits (86), Expect = 0.051
 Identities = 15/38 (39%), Positives = 20/38 (52%)

Query: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFG 394
           +Y G++ R   HG GT  WPDG +  G F      G+G
Sbjct: 113 SYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGYG 150



 Score = 35.4 bits (80), Expect = 0.26
 Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 1/59 (1%)

Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREG 416
           Y+GE+      G G   WP G ++ G F +   HG G  + P  S      Y  H REG
Sbjct: 91  YQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSH-REG 148



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 28/94 (29%), Positives = 37/94 (39%), Gaps = 8/94 (8%)

Query: 464 ERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLS 523
           E+ +    G     D  E YI + Q       GV   Q G  YQG F  +  +G G    
Sbjct: 56  EKEEEEAEGPLRAQDLRESYIQLVQ-------GVQEWQDGCMYQGEFGLNMKLGYGKFSW 108

Query: 524 EDDSLYEGTFTRDLTLMGKGKVTFPNGFTLEGSF 557
                Y G F RD    G G   +P+G +  G+F
Sbjct: 109 PTGESYHGQFYRD-HCHGLGTYMWPDGSSFTGTF 141



 Score = 31.2 bits (69), Expect = 4.8
 Identities = 21/70 (30%), Positives = 26/70 (37%), Gaps = 14/70 (20%)

Query: 413 WREGSM----------CGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGH 462
           W++G M           GYG   + T E Y G F     HG G        P    +TG 
Sbjct: 85  WQDGCMYQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTY----MWPDGSSFTGT 140

Query: 463 WERGQRSGYG 472
           +    R GYG
Sbjct: 141 FYLSHREGYG 150


>gi|18466802 Ras and Rab interactor 2 [Homo sapiens]
          Length = 895

 Score = 37.4 bits (85), Expect = 0.067
 Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 5/95 (5%)

Query: 834 FLSATECLQKIMTT---VDPREKLEVLERTYGEIEGTVSRVLGREYKLPMDDLLPLLIYV 890
           F+   +   K MT      P +K+ +L R    I   +    GR Y    DD LP+L YV
Sbjct: 648 FVDVEKIKVKFMTMQKMYSPEKKVMLLLRVCKLIYTVMENNSGRMYGA--DDFLPVLTYV 705

Query: 891 VSRARIQHLGAEIHLIRDMMDPNHTGGLYDFLLTA 925
           +++  +  L  EI  + +++DP+   G   + LT+
Sbjct: 706 IAQCDMLELDTEIEYMMELLDPSLLHGEGGYYLTS 740


>gi|224282170 MORN repeat containing 2 [Homo sapiens]
          Length = 79

 Score = 33.9 bits (76), Expect = 0.74
 Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 4/55 (7%)

Query: 418 MCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYG 472
           M G+G  E+ +  VY+G F++ + HG G        P   +YTG++   +  G G
Sbjct: 1   MNGFGRLEHFSGAVYEGQFKDNMFHGLGTY----TFPNGAKYTGNFNENRVEGEG 51



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 15/39 (38%), Positives = 21/39 (53%)

Query: 356 ATYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFG 394
           A YEG++     HG GT  +P+G  + GNF +    G G
Sbjct: 13  AVYEGQFKDNMFHGLGTYTFPNGAKYTGNFNENRVEGEG 51


>gi|108860690 chromosome 16 open reading frame 7 [Homo sapiens]
          Length = 631

 Score = 33.9 bits (76), Expect = 0.74
 Identities = 16/54 (29%), Positives = 31/54 (57%)

Query: 881 DDLLPLLIYVVSRARIQHLGAEIHLIRDMMDPNHTGGLYDFLLTALESCYEHIQ 934
           DDLLP+L +VV R+ +  L +E   + + +   +  G   + LT+L+S   +++
Sbjct: 569 DDLLPILSFVVLRSGLPQLVSECAALEEFIHEGYLIGEEGYCLTSLQSALSYVE 622


>gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens]
          Length = 1197

 Score = 32.7 bits (73), Expect = 1.7
 Identities = 28/141 (19%), Positives = 62/141 (43%), Gaps = 13/141 (9%)

Query: 618 LQEALLGFDVQSSRELRRSQDYLSCERTHPEDSVGSMEDILEELLQHREPKALQLYLRK- 676
           L+  +   + +  REL+ +Q  L C +T  + S   M++      + +E +A+ L L + 
Sbjct: 776 LENKMKNAEAERERELKDAQKKLDCAKTKADASSKKMKE------KQQEVEAITLELEEL 829

Query: 677 -----ALSNSLHPLGKLLRTLMLTFQATYAGVGANKHLQELAQEEVKQHAQELWAAYRGL 731
                +    L  + + +++     +   A V  NK     AQEEV +  +E+  A   +
Sbjct: 830 KREHTSYKQQLEAVNEAIKSYESQIEVMAAEVAKNKESVNKAQEEVTKQ-KEVITAQDTV 888

Query: 732 LRVALERKGQALEEDEDTETR 752
           ++       +  E++ D++ +
Sbjct: 889 IKAKYAEVAKHKEQNNDSQLK 909


>gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens]
          Length = 1197

 Score = 32.7 bits (73), Expect = 1.7
 Identities = 28/141 (19%), Positives = 62/141 (43%), Gaps = 13/141 (9%)

Query: 618 LQEALLGFDVQSSRELRRSQDYLSCERTHPEDSVGSMEDILEELLQHREPKALQLYLRK- 676
           L+  +   + +  REL+ +Q  L C +T  + S   M++      + +E +A+ L L + 
Sbjct: 776 LENKMKNAEAERERELKDAQKKLDCAKTKADASSKKMKE------KQQEVEAITLELEEL 829

Query: 677 -----ALSNSLHPLGKLLRTLMLTFQATYAGVGANKHLQELAQEEVKQHAQELWAAYRGL 731
                +    L  + + +++     +   A V  NK     AQEEV +  +E+  A   +
Sbjct: 830 KREHTSYKQQLEAVNEAIKSYESQIEVMAAEVAKNKESVNKAQEEVTKQ-KEVITAQDTV 888

Query: 732 LRVALERKGQALEEDEDTETR 752
           ++       +  E++ D++ +
Sbjct: 889 IKAKYAEVAKHKEQNNDSQLK 909


>gi|110347420 structural maintenance of chromosomes 2 [Homo sapiens]
          Length = 1197

 Score = 32.7 bits (73), Expect = 1.7
 Identities = 28/141 (19%), Positives = 62/141 (43%), Gaps = 13/141 (9%)

Query: 618 LQEALLGFDVQSSRELRRSQDYLSCERTHPEDSVGSMEDILEELLQHREPKALQLYLRK- 676
           L+  +   + +  REL+ +Q  L C +T  + S   M++      + +E +A+ L L + 
Sbjct: 776 LENKMKNAEAERERELKDAQKKLDCAKTKADASSKKMKE------KQQEVEAITLELEEL 829

Query: 677 -----ALSNSLHPLGKLLRTLMLTFQATYAGVGANKHLQELAQEEVKQHAQELWAAYRGL 731
                +    L  + + +++     +   A V  NK     AQEEV +  +E+  A   +
Sbjct: 830 KREHTSYKQQLEAVNEAIKSYESQIEVMAAEVAKNKESVNKAQEEVTKQ-KEVITAQDTV 888

Query: 732 LRVALERKGQALEEDEDTETR 752
           ++       +  E++ D++ +
Sbjct: 889 IKAKYAEVAKHKEQNNDSQLK 909


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 32.3 bits (72), Expect = 2.2
 Identities = 68/297 (22%), Positives = 113/297 (38%), Gaps = 50/297 (16%)

Query: 633 LRRSQDYLSCERTHPEDSVGSMEDILEELLQHREPKALQLYLR-KALSNSLHPLGKLLRT 691
           L++ QDY   E  H E+SV      ++  L  ++    QL  R  A   SLH        
Sbjct: 312 LKKEQDYTKLEEKHNEESVSKKN--IQATLHQKDLDCQQLQSRLSASETSLH-------- 361

Query: 692 LMLTFQATYAGVGANKHLQELAQEEVK-QHAQELWAAYRGLLRVALERKGQALEEDEDTE 750
             +  + +  G    K  +EL++ E K QH           L+   ++  Q  EE E   
Sbjct: 362 -RIHVELSEKGEATQKLKEELSEVETKYQH-----------LKAEFKQLQQQREEKEQ-- 407

Query: 751 TRDLQVHGLVLPLMLPSFYSELFTLYLLLHEREDSFYSQGIANLSLFPDTQLLEFLDVQK 810
                 HGL L   +   +S+L      L E       Q   +     D +  +  D+Q 
Sbjct: 408 ------HGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKE-QQVADLQL 460

Query: 811 HLWPLKD-----LTLTSNQRYSLVRDKCFLSATECLQKIMTTVDPREKLEVLERTYGEIE 865
            L  L++     +T ++  ++ L + K      + LQ+  TT   RE    LE+   +I 
Sbjct: 461 KLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQ-STTAKLREAQNDLEQVLRQIG 519

Query: 866 GTVSRVLGREYKLPMD-DLLPLL------IYVVSRARIQHLGAEIHLIRDMMDPNHT 915
               ++   E  L    + + LL      +Y    A+IQ    E  ++  + + NHT
Sbjct: 520 DKDQKIQNLEALLQKSKENISLLEKEREDLY----AKIQAGEGETAVLNQLQEKNHT 572


>gi|223278407 MORN repeat containing 5 [Homo sapiens]
          Length = 161

 Score = 32.0 bits (71), Expect = 2.8
 Identities = 19/59 (32%), Positives = 23/59 (38%), Gaps = 5/59 (8%)

Query: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREG 416
           Y GE+  GR  GK     P    +VG    G+ HG G    P  S+     Y   W  G
Sbjct: 8   YIGEYVDGRMEGKAKYILPTETIYVGEMKDGMFHGEGTLYFPSGSQ-----YDAIWENG 61


>gi|4506123 PRP18 pre-mRNA processing factor 18 homolog [Homo
           sapiens]
          Length = 342

 Score = 32.0 bits (71), Expect = 2.8
 Identities = 22/81 (27%), Positives = 39/81 (48%), Gaps = 11/81 (13%)

Query: 643 ERTHPEDSVGSMEDILEELLQHREPKALQLYLRKALSNSLHPLGKLLRTLMLTFQATYAG 702
           +R  P D   S+ DI++ +LQ    KA   YL+ A+ N+  P+G       +T    +A 
Sbjct: 239 KRNLPADIKESITDIIKFMLQREYVKANDAYLQMAIGNAPWPIG-------VTMVGIHAR 291

Query: 703 VGA----NKHLQELAQEEVKQ 719
            G     +KH+  +  +E ++
Sbjct: 292 TGREKIFSKHVAHVLNDETQR 312


>gi|82659109 retinoblastoma-associated factor 600 [Homo sapiens]
          Length = 5183

 Score = 32.0 bits (71), Expect = 2.8
 Identities = 19/65 (29%), Positives = 31/65 (47%)

Query: 646  HPEDSVGSMEDILEELLQHREPKALQLYLRKALSNSLHPLGKLLRTLMLTFQATYAGVGA 705
            H + + G  E ILEE LQ+ E +      RKA+       G+L++ +M T     +    
Sbjct: 1365 HADPNSGLDESILEECLQYLEKQLESSQARKAMEEFFSDSGELVQIMMATANENLSAKFC 1424

Query: 706  NKHLQ 710
            N+ L+
Sbjct: 1425 NRVLK 1429


>gi|18034775 PHD finger protein 20 [Homo sapiens]
          Length = 1012

 Score = 31.6 bits (70), Expect = 3.7
 Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 6/63 (9%)

Query: 386 CQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFG 445
           CQ  +HG  + LL +   +K+ CY C    G   G+   +Y  D   K +   G  HG  
Sbjct: 672 CQCWQHGVCMGLLEENVPEKYTCYVCQDPPGQRPGF---KYWYD---KEWLSRGHMHGLA 725

Query: 446 VLE 448
            LE
Sbjct: 726 FLE 728


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,897,362
Number of Sequences: 37866
Number of extensions: 1977815
Number of successful extensions: 5058
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 4671
Number of HSP's gapped (non-prelim): 173
length of query: 953
length of database: 18,247,518
effective HSP length: 112
effective length of query: 841
effective length of database: 14,006,526
effective search space: 11779488366
effective search space used: 11779488366
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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