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Search of human proteins with 33356552
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33356552 G patch domain containing 4 isoform 1 [Homo
sapiens]
(375 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33356552 G patch domain containing 4 isoform 1 [Homo sapiens] 763 0.0
gi|33356550 G patch domain containing 4 isoform 2 [Homo sapiens] 741 0.0
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 64 3e-10
gi|148747556 PIN2-interacting protein 1 [Homo sapiens] 63 5e-10
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 62 1e-09
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 60 3e-09
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 55 1e-07
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 54 2e-07
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 54 3e-07
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 53 5e-07
gi|148746195 trichohyalin [Homo sapiens] 53 5e-07
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 52 7e-07
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 52 7e-07
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 52 7e-07
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 52 7e-07
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 52 7e-07
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ... 52 9e-07
gi|50962882 G patch domain containing 8 [Homo sapiens] 51 1e-06
gi|117553584 adaptor-related protein complex 3, delta 1 subunit ... 49 7e-06
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 49 7e-06
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 49 7e-06
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 49 7e-06
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 49 1e-05
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 48 2e-05
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 48 2e-05
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 47 2e-05
gi|118600973 RNA binding motif protein, X-linked 2 [Homo sapiens] 47 2e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 47 4e-05
gi|33356179 transcription termination factor, RNA polymerase I [... 47 4e-05
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 47 4e-05
>gi|33356552 G patch domain containing 4 isoform 1 [Homo sapiens]
Length = 375
Score = 763 bits (1969), Expect = 0.0
Identities = 375/375 (100%), Positives = 375/375 (100%)
Query: 1 MFPRSGPSNDEVKSRGMKFAEEQLLKHGWTQGKGLGRKENGITQALRVTLKQDTHGVGHD 60
MFPRSGPSNDEVKSRGMKFAEEQLLKHGWTQGKGLGRKENGITQALRVTLKQDTHGVGHD
Sbjct: 1 MFPRSGPSNDEVKSRGMKFAEEQLLKHGWTQGKGLGRKENGITQALRVTLKQDTHGVGHD 60
Query: 61 PAKEFTNHWWNELFNKTAANLVVETGQDGVQIRSLSKETTRYNHPKPNLLYQKFVKMATL 120
PAKEFTNHWWNELFNKTAANLVVETGQDGVQIRSLSKETTRYNHPKPNLLYQKFVKMATL
Sbjct: 61 PAKEFTNHWWNELFNKTAANLVVETGQDGVQIRSLSKETTRYNHPKPNLLYQKFVKMATL 120
Query: 121 TSGGEKPNKDLESCSDDDNQGSKSPKILTDEMLLQACEGRTAHKAARLGITMKAKLARLE 180
TSGGEKPNKDLESCSDDDNQGSKSPKILTDEMLLQACEGRTAHKAARLGITMKAKLARLE
Sbjct: 121 TSGGEKPNKDLESCSDDDNQGSKSPKILTDEMLLQACEGRTAHKAARLGITMKAKLARLE 180
Query: 181 AQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQ 240
AQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQ
Sbjct: 181 AQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQ 240
Query: 241 NIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKR 300
NIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKR
Sbjct: 241 NIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKR 300
Query: 301 WHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEE 360
WHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEE
Sbjct: 301 WHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEE 360
Query: 361 TFRWWNQGSREQSMQ 375
TFRWWNQGSREQSMQ
Sbjct: 361 TFRWWNQGSREQSMQ 375
>gi|33356550 G patch domain containing 4 isoform 2 [Homo sapiens]
Length = 370
Score = 741 bits (1913), Expect = 0.0
Identities = 365/365 (100%), Positives = 365/365 (100%)
Query: 11 EVKSRGMKFAEEQLLKHGWTQGKGLGRKENGITQALRVTLKQDTHGVGHDPAKEFTNHWW 70
EVKSRGMKFAEEQLLKHGWTQGKGLGRKENGITQALRVTLKQDTHGVGHDPAKEFTNHWW
Sbjct: 6 EVKSRGMKFAEEQLLKHGWTQGKGLGRKENGITQALRVTLKQDTHGVGHDPAKEFTNHWW 65
Query: 71 NELFNKTAANLVVETGQDGVQIRSLSKETTRYNHPKPNLLYQKFVKMATLTSGGEKPNKD 130
NELFNKTAANLVVETGQDGVQIRSLSKETTRYNHPKPNLLYQKFVKMATLTSGGEKPNKD
Sbjct: 66 NELFNKTAANLVVETGQDGVQIRSLSKETTRYNHPKPNLLYQKFVKMATLTSGGEKPNKD 125
Query: 131 LESCSDDDNQGSKSPKILTDEMLLQACEGRTAHKAARLGITMKAKLARLEAQEQAFLARL 190
LESCSDDDNQGSKSPKILTDEMLLQACEGRTAHKAARLGITMKAKLARLEAQEQAFLARL
Sbjct: 126 LESCSDDDNQGSKSPKILTDEMLLQACEGRTAHKAARLGITMKAKLARLEAQEQAFLARL 185
Query: 191 KGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKR 250
KGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKR
Sbjct: 186 KGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKR 245
Query: 251 RHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGV 310
RHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGV
Sbjct: 246 RHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGV 305
Query: 311 LEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSR 370
LEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSR
Sbjct: 306 LEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSR 365
Query: 371 EQSMQ 375
EQSMQ
Sbjct: 366 EQSMQ 370
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 63.5 bits (153), Expect = 3e-10
Identities = 74/348 (21%), Positives = 140/348 (40%), Gaps = 32/348 (9%)
Query: 38 KENGITQALRVTLKQDTHGVGHDPAKEFTNHWWNELFNKTAANLVVETGQDGVQIRSLSK 97
K + + + + T+K+D+ D + F K + + + + K
Sbjct: 869 KSDSVAKLILETVKEDSKERRRDSRAREKRDYREPFFRKKDRDYLDKNSEK-------RK 921
Query: 98 ETTRYNHPKPNLLYQKFVKMATLTSGGEKPNKDLESCSDDDNQGSKSPKILTDEMLLQAC 157
E T + P L +K K G LESC + + +K + +E+ C
Sbjct: 922 EQTEKHKSVPGYLSEKDKKRRESAEAGRDRKDALESCKERRDGRAKPEEAHREELKECGC 981
Query: 158 EGRTAHKAARLGITMKAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQK 217
E K+ G K LE E+ AR K + G + + E P++ K+K K
Sbjct: 982 ESGFKDKSD--GDFGKG----LEPWERHHPAREKEKKDGPDKERKEKTKPERYKEKSSDK 1035
Query: 218 EEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTS 277
++ E + E+ D++ + ++ +K K+K + GK + + +G EK++ A
Sbjct: 1036 DKSEKSILEKCQKDKEFDKCFKE--KKDTKEKHKDTHGKDKERKASLDQGKEKKEKAFPG 1093
Query: 278 GLGELNSREQTNQSLRKGKKKKRWH--------HEEEKMGVLEEGGKGKEAAGSVRTEEV 329
+ E S ++ + +KGK+K W+ E+++ + G K EA+ RT+ +
Sbjct: 1094 IISEDFSEKKDD---KKGKEKS-WYIADIFTDESEDDRDSCMGSGFKMGEASDLPRTDGL 1149
Query: 330 ESR-----AYADPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSREQ 372
+ + AYA R+ +Q E + E R R R++
Sbjct: 1150 QEKEEGREAYASDRHRKSSDKQHPERQKDKEPRDRRKDRGAADAGRDK 1197
Score = 42.7 bits (99), Expect = 5e-04
Identities = 34/142 (23%), Positives = 64/142 (45%), Gaps = 4/142 (2%)
Query: 215 RQKEE-EEATASERN--DADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKE 271
++KEE EA AS+R+ +D++HPE + + ++K R + + + K EK+
Sbjct: 1150 QEKEEGREAYASDRHRKSSDKQHPERQKDKEPRDRRKDRGAADAGRDKKEKVFEKHKEKK 1209
Query: 272 DAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVES 331
D T + R + + K K K++ + EK E+ K K S + E
Sbjct: 1210 DKESTEKYKDRKDRASVDSTQDK-KNKQKLPEKAEKKHAAEDKAKSKHKEKSDKEHSKER 1268
Query: 332 RAYADPCSRRKKRQQQEEEDLN 353
++ + + ++ EEE L+
Sbjct: 1269 KSSRSADAEKSLLEKLEEEALH 1290
Score = 36.6 bits (83), Expect = 0.038
Identities = 53/261 (20%), Positives = 97/261 (37%), Gaps = 53/261 (20%)
Query: 64 EFTNHW------------WNE---LFNKTAANLVVET--GQDGVQIRSLSKETTRYNHPK 106
+ T HW W+E L + T L E+ +G + SL R H K
Sbjct: 541 QHTKHWRTDNWKTISSPAWSEVSSLSDSTRTRLTSESDYSSEGSSVESLKPVRKRQEHRK 600
Query: 107 PNLLYQKFVKMATLTSGG------------------EKPNKDLESCS------------D 136
L +K + G + NK+ CS +
Sbjct: 601 RASLSEKKSPFLSSAEGAVPKLDKEGKVVKKHKTKHKHKNKEKGQCSISQELKLKSFTYE 660
Query: 137 DDNQGSKSPKILTDEMLLQACEGRTAHKAARLGITMKAKLARLEAQEQAFLARLKGQDPG 196
++ KS K + E L K R + KL++++ +E+ +L + +
Sbjct: 661 YEDSKQKSDKAILLENDLSTENKLKVLKHDRDHFKKEEKLSKMKLEEKEWLFKDEKSLKR 720
Query: 197 APQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSK------KKKR 250
+ +++K R K E+E + E++ +EK + E+ +KSK +KK
Sbjct: 721 IKDTNKDISRSFREEKDRSNKAEKERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKN 780
Query: 251 RHQEGKVSDEREGTTKGNEKE 271
+E K+S E+E K ++++
Sbjct: 781 DLKEDKISKEKEKIFKEDKEK 801
Score = 35.4 bits (80), Expect = 0.084
Identities = 67/329 (20%), Positives = 126/329 (38%), Gaps = 47/329 (14%)
Query: 86 GQDGVQIRSLSKETTRYNHPKPNLLYQKFVKMATLTSGGEKP-----------NKDLESC 134
G+D + SL + + P ++ + F + G EK D +SC
Sbjct: 1071 GKDKERKASLDQGKEKKEKAFPGIISEDFSEKKDDKKGKEKSWYIADIFTDESEDDRDSC 1130
Query: 135 SDDDNQGSKSPKILTDEMLLQACEGRTAHKAARLGITMKAKLARLEAQEQAFLARLKGQD 194
+ ++ + + L + EGR A+ + R K+ + +++ R + +D
Sbjct: 1131 MGSGFKMGEASDLPRTDGLQEKEEGREAYASDR---HRKSSDKQHPERQKDKEPRDRRKD 1187
Query: 195 PGAPQLQSESKPP---KKKKKKRRQKEEEEATASERNDAD--------EKHPEHAEQNIR 243
GA + K K K+KK ++ E+ +R D +K PE AE+
Sbjct: 1188 RGAADAGRDKKEKVFEKHKEKKDKESTEKYKDRKDRASVDSTQDKKNKQKLPEKAEKKHA 1247
Query: 244 KSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNS------REQTNQSLRKGKK 297
K K +H+E SD+ + + + A S L +L RE +N + +
Sbjct: 1248 AEDKAKSKHKE--KSDKEHSKERKSSRSADAEKSLLEKLEEEALHEYREDSNDKISEVSS 1305
Query: 298 KKRWHHEEE-------KMGVLEEGGKGKEAAGSVRTEEV-ESRAYADPCSRRKK---RQQ 346
+E ++ E G K + E++ E + S KK R++
Sbjct: 1306 DSFTDRGQEPGLTAFLEVSFTEPPGDDKPRESACLPEKLKEKERHRHSSSSSKKSHDRER 1365
Query: 347 QEEEDLNLEDRGEETFRWWNQGSREQSMQ 375
++E +++GE+ + GSR+ S Q
Sbjct: 1366 AKKEKAEKKEKGED---YKEGGSRKDSGQ 1391
Score = 30.8 bits (68), Expect = 2.1
Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 15/61 (24%)
Query: 233 KHPEHAEQNIRKSKKKKRRHQE--------GKVSD-------EREGTTKGNEKEDAAGTS 277
+ P +A+Q K+K KK+R +E GK SD E E + G + D+ G+S
Sbjct: 440 REPSNAKQQKEKNKVKKKRKKETKGREVRFGKRSDKFCSSESESESSESGEDDRDSLGSS 499
Query: 278 G 278
G
Sbjct: 500 G 500
Score = 29.6 bits (65), Expect = 4.6
Identities = 19/71 (26%), Positives = 34/71 (47%)
Query: 191 KGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKR 250
K + A + +S + K++K R KEE + + +R EK + E I K K+K
Sbjct: 736 KDRSNKAEKERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDLKEDKISKEKEKIF 795
Query: 251 RHQEGKVSDER 261
+ + K+ E+
Sbjct: 796 KEDKEKLKKEK 806
Score = 29.6 bits (65), Expect = 4.6
Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Query: 190 LKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKK 249
LK + P +L+ + KKK K R K E++ E D K E + ++ KK+
Sbjct: 748 LKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDLKE--DKISKEKEKIFKEDKEKLKKE 805
Query: 250 RRHQEGKVSDEREGTTKGNEKED 272
+ ++E DE + E ED
Sbjct: 806 KVYREDSAFDEYCNKNQFLENED 828
Score = 29.6 bits (65), Expect = 4.6
Identities = 36/182 (19%), Positives = 75/182 (41%), Gaps = 9/182 (4%)
Query: 185 AFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRK 244
AFL + PG + + + P+K K+K R + +++ + +D + E AE+
Sbjct: 1319 AFLEVSFTEPPGDDKPRESACLPEKLKEKERHRHSS-SSSKKSHDRERAKKEKAEK---- 1373
Query: 245 SKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLR---KGKKKKRW 301
K+K ++EG + K + DA G S + + ++ ++++ KK K
Sbjct: 1374 -KEKGEDYKEGGSRKDSGQYEKDFLEADAYGVSYNMKADIEDELDKTIELFSTEKKDKND 1432
Query: 302 HHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEET 361
E + +E +A ++ E+ + + + K+R + D L +E
Sbjct: 1433 SEREPSKKIEKELKPYGSSAINILKEKKKREKHREKWRDEKERHRDRHADGLLRHHRDEL 1492
Query: 362 FR 363
R
Sbjct: 1493 LR 1494
>gi|148747556 PIN2-interacting protein 1 [Homo sapiens]
Length = 328
Score = 62.8 bits (151), Expect = 5e-10
Identities = 72/255 (28%), Positives = 106/255 (41%), Gaps = 19/255 (7%)
Query: 7 PSNDEVKSRGMKFAEEQLLKHGWTQGKGLGRKENGITQALRVTLKQDTHGVGHDPAKEFT 66
P N + KF + L K GW++GKGLG +E G T ++V +K + G+G E
Sbjct: 17 PQNTAWSNDDSKFGQRMLEKMGWSKGKGLGAQEQGATDHIKVQVKNNHLGLGATINNEDN 76
Query: 67 NHWWNELFNKTAANLVVETGQ------DGVQIRSLSKETTRYNHPKPNLLYQKFVKMATL 120
+ FN+ A L GQ D + +S S E + K + Y KF K L
Sbjct: 77 WIAHQDDFNQLLAELNTCHGQETTDSSDKKEKKSFSLE-EKSKISKNRVHYMKFTKGKDL 135
Query: 121 TSGGEKPNKDLESCSDDDNQGSKSPKILTDEMLLQACEGRTAHKAARLGITMKAKLA-RL 179
+S + DL+ C Q K+P+ D E T +A T++ A R+
Sbjct: 136 SS---RSKTDLD-CIFGKRQSKKTPE--GDASPSTPEENETTTTSA---FTIQEYFAKRM 186
Query: 180 EAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAE 239
A + + G D + Q E K KK+ K+ K+ E + E PE AE
Sbjct: 187 AALKNKPQVPVPGSD--ISETQVERKRGKKRNKEATGKDVESYLQPKAKRHTEGKPERAE 244
Query: 240 QNIRKSKKKKRRHQE 254
R +KKK +E
Sbjct: 245 AQERVAKKKSAPAEE 259
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 61.6 bits (148), Expect = 1e-09
Identities = 43/189 (22%), Positives = 86/189 (45%), Gaps = 17/189 (8%)
Query: 201 QSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDE 260
+ E + +KK+++ R+K + E + + +K + + + +KK+RR +E K +E
Sbjct: 52 KKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEE 111
Query: 261 REGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEK------------M 308
+E K +KE + E +E+ + RK +++K+ E+E+ +
Sbjct: 112 KEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQV 171
Query: 309 GVLEEGGKGKEAAGSV-----RTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFR 363
G EE K KE R E + R + R+K+R+++EE + + +R
Sbjct: 172 GEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWR 231
Query: 364 WWNQGSREQ 372
+G RE+
Sbjct: 232 EKERGKRER 240
Score = 50.8 bits (120), Expect = 2e-06
Identities = 42/180 (23%), Positives = 83/180 (46%), Gaps = 12/180 (6%)
Query: 198 PQLQSESKPPKKKKKKRRQ--KEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEG 255
P QSE + +++ + R++ KE E ER + +++ E ++ R+ KK+++ +
Sbjct: 32 PGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERK 91
Query: 256 KVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGG 315
K +ERE + EKE+ GE + + + +G+ K E K E
Sbjct: 92 K--EERERKKRRREKENKE-----GEEKEKRKKKEKKERGRTSKEGKERERKEERKREER 144
Query: 316 KGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSREQSMQ 375
K +E R +E E + + R +K+ ++EE+ ++R E R N+ R++ +
Sbjct: 145 KERERKKEEREKERERK---ERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERE 201
Score = 48.9 bits (115), Expect = 7e-06
Identities = 37/161 (22%), Positives = 71/161 (44%), Gaps = 8/161 (4%)
Query: 173 KAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKE------EEEATASE 226
K K + +E+ R + ++ + + + K +KK++ R KE +EE E
Sbjct: 84 KEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREE 143
Query: 227 RNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSRE 286
R + + K E ++ RK +KK+ R Q G+ +ER+ + K+ RE
Sbjct: 144 RKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRK--ERKKERE 201
Query: 287 QTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTE 327
+ + RK ++KK+ ++E+ + + KE R E
Sbjct: 202 RKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
Score = 44.7 bits (104), Expect = 1e-04
Identities = 42/212 (19%), Positives = 87/212 (41%), Gaps = 34/212 (16%)
Query: 158 EGRTAHKAARLGITMKAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQK 217
EG+ ++ R + + + E +++ R K + G K +++KK+RR+K
Sbjct: 50 EGKKERESERKKERREREKRKREREKERKRERGKKEKKG-----ERKKEERERKKRRREK 104
Query: 218 EEEEATASERNDADEKHPE----------HAEQNIRKSKKKKRRHQEGKVSDEREGTTKG 267
E +E E+ EK ++ ++ ++K+R ++ + ERE +
Sbjct: 105 ENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERK 164
Query: 268 NEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTE 327
+ G E+ + RK +KK+ + +E K KE R E
Sbjct: 165 KRERKQVG-------EKEEERKEKERKERKKRERNRKERK----------KERERKERRE 207
Query: 328 EVESRAYADPCSRRKKRQQQEEEDLNLEDRGE 359
+ R + R+K+RQ+ + + ++RG+
Sbjct: 208 RKKERKKKE--ERKKERQKDRQTNWREKERGK 237
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 60.1 bits (144), Expect = 3e-09
Identities = 46/160 (28%), Positives = 72/160 (45%), Gaps = 18/160 (11%)
Query: 201 QSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDE 260
+ K KKK+KKR + +E E ER ++ E + +K KKK+ R Q G+
Sbjct: 56 RERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGR---- 111
Query: 261 REGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLE-EGGKGKE 319
RE K KE RE+ N+ R+ K+KKR + K E E GK +
Sbjct: 112 RERKKKKERKE-------------RERENKQRRERKRKKRRKKKRRKERKREKERGKRER 158
Query: 320 AAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGE 359
+ EE E + + R+K+R+++E + E + E
Sbjct: 159 KRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKE 198
Score = 50.1 bits (118), Expect = 3e-06
Identities = 42/163 (25%), Positives = 67/163 (41%), Gaps = 12/163 (7%)
Query: 202 SESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDER 261
S P +++ R+KE E +R E+ E + +K KKK+++ + GK ER
Sbjct: 23 SHISKPCTQRESERKKERREREKRKR----EREKERKRERGKKEKKKRKKRERGK---ER 75
Query: 262 EGTTKGNEKE-----DAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGK 316
E K EK+ + E RE+ + R+ KKKK E + E +
Sbjct: 76 ERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR 135
Query: 317 GKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGE 359
K R E + +RKKR+++E E +R E
Sbjct: 136 KKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKE 178
Score = 49.3 bits (116), Expect = 6e-06
Identities = 34/150 (22%), Positives = 68/150 (45%), Gaps = 2/150 (1%)
Query: 160 RTAHKAARLGITMKAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEE 219
R + G K K + E ++ R + + + + E + KK+KKKR +K+
Sbjct: 50 REKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQR 109
Query: 220 EEATASERNDADEKHPEHAEQNIRKSKK--KKRRHQEGKVSDEREGTTKGNEKEDAAGTS 277
++ + E+ E+ ++ RK KK KK+R +E K ER + +K
Sbjct: 110 GRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEERE 169
Query: 278 GLGELNSREQTNQSLRKGKKKKRWHHEEEK 307
E N +E+ + RK +++++ ++E+
Sbjct: 170 KKRERNRKERKKERERKERRERKKERKKER 199
Score = 48.1 bits (113), Expect = 1e-05
Identities = 41/162 (25%), Positives = 71/162 (43%), Gaps = 10/162 (6%)
Query: 189 RLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDAD-EKHPEHAEQNIRKSKK 247
R +G+ + + E +++K+K R+K+ +E ER EK +Q R+ +K
Sbjct: 56 RERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERK 115
Query: 248 KKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEK 307
KK+ +E ERE + K + RE+ + R+ K+KKR E EK
Sbjct: 116 KKKERKE----RERENKQRRERKRKKRRKKKRRKERKREK-ERGKRERKRKKRKKEEREK 170
Query: 308 MGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEE 349
+ KE R E + R RRKK++++++
Sbjct: 171 KRERNRKERKKERERKERRERKKERKK----ERRKKKERKKD 208
Score = 38.5 bits (88), Expect = 0.010
Identities = 30/135 (22%), Positives = 60/135 (44%), Gaps = 18/135 (13%)
Query: 178 RLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEK---- 233
R E +E+ R K + + + + KKK++K R++E ++ +R +K
Sbjct: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145
Query: 234 -HPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSL 292
E+ R+ K+KKR+ +E + ER + E+E R++ +
Sbjct: 146 ERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERE-------------RKERRERK 192
Query: 293 RKGKKKKRWHHEEEK 307
++ KK++R E +K
Sbjct: 193 KERKKERRKKKERKK 207
Score = 36.6 bits (83), Expect = 0.038
Identities = 29/130 (22%), Positives = 59/130 (45%), Gaps = 3/130 (2%)
Query: 243 RKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWH 302
R+S++KK R + K ERE K ++E + R + + RK ++K+R
Sbjct: 32 RESERKKERREREKRKRERE---KERKRERGKKEKKKRKKRERGKERERKRKEREKQRKE 88
Query: 303 HEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETF 362
E++ ++ K +E R E + + + K+R++++ + + R +E
Sbjct: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
Query: 363 RWWNQGSREQ 372
R +G RE+
Sbjct: 149 REKERGKRER 158
Score = 36.6 bits (83), Expect = 0.038
Identities = 18/61 (29%), Positives = 37/61 (60%), Gaps = 1/61 (1%)
Query: 203 ESKPPKKKKKKRRQKEEEEATASERNDAD-EKHPEHAEQNIRKSKKKKRRHQEGKVSDER 261
E + K+++K++++K+EE ERN + +K E E+ RK ++KK R ++ + +R
Sbjct: 150 EKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDR 209
Query: 262 E 262
+
Sbjct: 210 K 210
Score = 33.5 bits (75), Expect = 0.32
Identities = 12/54 (22%), Positives = 30/54 (55%)
Query: 208 KKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDER 261
KK+KK+ R+K+ E + + + K ++ +K ++KK+ ++ + +D +
Sbjct: 161 KKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQ 214
Score = 32.7 bits (73), Expect = 0.55
Identities = 14/72 (19%), Positives = 37/72 (51%)
Query: 189 RLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKK 248
R + ++ G + + + + ++++KKR + +E ER + E+ E ++ +K ++K
Sbjct: 147 RKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERK 206
Query: 249 KRRHQEGKVSDE 260
K R + + +
Sbjct: 207 KDRKTDRQTDSQ 218
Score = 31.2 bits (69), Expect = 1.6
Identities = 15/74 (20%), Positives = 40/74 (54%), Gaps = 1/74 (1%)
Query: 201 QSESKPPKKK-KKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSD 259
+ E K K++ K++R++K+ ++ ++ + + K + + + ++KK R +E +
Sbjct: 144 RKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKK 203
Query: 260 EREGTTKGNEKEDA 273
ER+ K + + D+
Sbjct: 204 ERKKDRKTDRQTDS 217
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 54.7 bits (130), Expect = 1e-07
Identities = 49/154 (31%), Positives = 74/154 (48%), Gaps = 34/154 (22%)
Query: 208 KKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKG 267
KKKKKK+++ EE E T +E E ++ RK K+K++R ++ K +E T K
Sbjct: 1 KKKKKKKKETEETEET-------EETEEEEEKEGKRKEKRKEKRKEKEKKKKTKE-TEKR 52
Query: 268 NEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTE 327
EKE E+ + RK KKKK EEE+ EE + KE E
Sbjct: 53 KEKE--------------EEEKKRKRKRKKKKE---EEEREEEEEEEEEEKE-----EEE 90
Query: 328 EVESRAYADPCSRRKKRQQQEEEDLNLEDRGEET 361
+ E R ++KKR+++EEE+ + R +T
Sbjct: 91 KEEGRRR----KKKKKRRRKEEEEEKKKKRRRKT 120
Score = 53.5 bits (127), Expect = 3e-07
Identities = 24/70 (34%), Positives = 42/70 (60%)
Query: 201 QSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDE 260
+ E + K+K+K++++KEEEE E + +EK E E+ R+ KKKKRR +E + +
Sbjct: 54 EKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113
Query: 261 REGTTKGNEK 270
++ K +K
Sbjct: 114 KKRRRKTKKK 123
Score = 52.0 bits (123), Expect = 9e-07
Identities = 29/109 (26%), Positives = 57/109 (52%), Gaps = 16/109 (14%)
Query: 199 QLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVS 258
+ + E + K+K+KR++K +E+ + + +++ + E+ RK K+KK++ +E +
Sbjct: 18 ETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREE 77
Query: 259 DEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEK 307
+E E + EKE+ E+ + R+ KKKKR EEE+
Sbjct: 78 EEEE---EEEEKEE-------------EEKEEGRRRKKKKKRRRKEEEE 110
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 53.9 bits (128), Expect = 2e-07
Identities = 46/185 (24%), Positives = 78/185 (42%), Gaps = 11/185 (5%)
Query: 191 KGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKR 250
+G+ G + + E K ++ ++ + EEEE + E E E + + +
Sbjct: 907 EGEGEGEEE-EGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGE 965
Query: 251 RHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGV 310
+EG+ E EG +G E+E G GE E+ + +G+++ EEE+ G
Sbjct: 966 GEEEGEGEGE-EGEGEGEEEEG----EGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGE 1020
Query: 311 LEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSR 370
+E +G+E G EE E R+K + EE N E+ EE ++ G
Sbjct: 1021 VEGEVEGEEGEGEGEEEEGEEEG-----EEREKEGEGEENRRNREEEEEEEGKYQETGEE 1075
Query: 371 EQSMQ 375
E Q
Sbjct: 1076 ENERQ 1080
Score = 53.1 bits (126), Expect = 4e-07
Identities = 43/171 (25%), Positives = 78/171 (45%), Gaps = 8/171 (4%)
Query: 196 GAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEK--HPEHAEQNIRKSKKKKRRHQ 253
G +L + + K+ +++ QKE E+ ERN E+ EH E + +++ +
Sbjct: 692 GEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEK 751
Query: 254 EGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQS---LRKGKKKK-RWHHEEEKMG 309
EG+ +E EG E+E G E +E+ + +G++++ EE++ G
Sbjct: 752 EGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEG 811
Query: 310 VLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEE 360
EGG+ +E G EE E + ++ + EEE+ E +GEE
Sbjct: 812 GEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEE--GEGKGEE 860
Score = 50.1 bits (118), Expect = 3e-06
Identities = 45/169 (26%), Positives = 72/169 (42%), Gaps = 20/169 (11%)
Query: 195 PGAPQLQSESKPPKKKKKKR--RQKEEEEATASERNDADEK--HPEHAEQNIRKSKKKKR 250
PG + + K KK+ QKE E+ ERN E+ EH E + +++
Sbjct: 689 PGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEE 748
Query: 251 RHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGV 310
+EG+ +E EG E+E GE E+ + + ++ + EEE+
Sbjct: 749 EEKEGEGKEEGEGEEVEGEREKEE-----GERKKEERAGKEEKGEEEGDQGEGEEEE--- 800
Query: 311 LEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGE 359
E G+ KE G V EVE + +R+++EEE E+ GE
Sbjct: 801 TEGRGEEKEEGGEVEGGEVE--------EGKGEREEEEEEGEGEEEEGE 841
Score = 45.8 bits (107), Expect = 6e-05
Identities = 40/169 (23%), Positives = 71/169 (42%), Gaps = 10/169 (5%)
Query: 192 GQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRR 251
G++ + E ++++K+ KEE E E E+ E+ K +K +
Sbjct: 731 GEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEE 790
Query: 252 HQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVL 311
+G+ +E E +G EKE+ GE+ E + ++++ EEE+
Sbjct: 791 GDQGE-GEEEETEGRGEEKEEG------GEVEGGEVEEGKGEREEEEEEGEGEEEEGEGE 843
Query: 312 EEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEE 360
EE G+G+E G + EE + + + +EEE E GEE
Sbjct: 844 EEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEG---EGEGEE 889
Score = 45.1 bits (105), Expect = 1e-04
Identities = 42/183 (22%), Positives = 79/183 (43%), Gaps = 11/183 (6%)
Query: 201 QSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHA-EQNIRKSKKKKRRHQEGKVS- 258
+ E ++++ R ++EE+E E + +E E E+ RK +++ + ++G+
Sbjct: 732 EEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEG 791
Query: 259 -----DEREGTTKGNEKEDAAGTSG--LGELNSREQTNQSLRKGKKKKRWHHEEEKMGVL 311
+E E +G EKE+ G + E + + +G++++ EEE G
Sbjct: 792 DQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEE 851
Query: 312 EEG-GKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEE-EDLNLEDRGEETFRWWNQGS 369
EEG GKG+E EE + + + +EE E E+ GE +G
Sbjct: 852 EEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGE 911
Query: 370 REQ 372
E+
Sbjct: 912 GEE 914
Score = 43.5 bits (101), Expect = 3e-04
Identities = 44/186 (23%), Positives = 71/186 (38%), Gaps = 26/186 (13%)
Query: 212 KKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKR-----------------RHQE 254
K R++EEEE E E+ E+ + K ++ +E
Sbjct: 823 KGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEE 882
Query: 255 GKVSDEREGTTKGNEK--EDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLE 312
G+ E EG +G E+ E G GE E + +G++ + EEE G E
Sbjct: 883 GEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGE 942
Query: 313 EG-GKGKEAAGSVRTEEVESRAYADPCSRRK------KRQQQEEEDLNLEDRGEETFRWW 365
+G G+G+E G EE E + + + +++E E E+ GEE
Sbjct: 943 DGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEE 1002
Query: 366 NQGSRE 371
+G E
Sbjct: 1003 GEGEEE 1008
Score = 43.1 bits (100), Expect = 4e-04
Identities = 40/163 (24%), Positives = 71/163 (43%), Gaps = 5/163 (3%)
Query: 201 QSESKPPKKKKKKRRQKEEEEATASERNDADEKHPE-HAEQNIRKSKKKKRRHQEGKVSD 259
+ E + ++KK++R KEE+ ++ + +E+ E E+ + + +EGK
Sbjct: 767 EREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGER 826
Query: 260 EREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGV-LEEGGKGK 318
E E E+E+ G GE E + +G++ + EE G EE G+G+
Sbjct: 827 EEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGE 886
Query: 319 -EAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEE 360
E G EE E + + ++EE + E+ GEE
Sbjct: 887 GEEEGEGEGEEEEGEGEGE--EEGEGEGEEEEGEGKGEEEGEE 927
Score = 42.0 bits (97), Expect = 9e-04
Identities = 43/186 (23%), Positives = 78/186 (41%), Gaps = 14/186 (7%)
Query: 191 KGQDPG----APQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSK 246
KG++ G + ++E + +K++ + E E ER + +E+ E+ + +
Sbjct: 786 KGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEE 845
Query: 247 KKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEE 306
+ + +EG+ E EG E+E G G GE E + +G+ + E E
Sbjct: 846 EGEGEEEEGEGKGEEEGEEGEGEEE---GEEGEGEGEEEEGEGEGEEEGEGEGE-EEEGE 901
Query: 307 KMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFRWWN 366
G E G+G+E G + EE + + ++ E E + E GEE W
Sbjct: 902 GEGEEEGEGEGEEEEGEGKGEEEGEEGEGE-----GEEEEGEGEGEDGEGEGEEEEGEW- 955
Query: 367 QGSREQ 372
+G E+
Sbjct: 956 EGEEEE 961
Score = 41.6 bits (96), Expect = 0.001
Identities = 46/206 (22%), Positives = 84/206 (40%), Gaps = 19/206 (9%)
Query: 169 GITMKAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERN 228
G + K R E +E+ +G++ + E + +++ + + ++E EE E
Sbjct: 817 GEVEEGKGEREEEEEEG-----EGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEG 871
Query: 229 DADEKH--PEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKE-----DAAGTSGLGE 281
+ E E E + + + +EG+ E EG +G E+E + G G GE
Sbjct: 872 EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGE 931
Query: 282 LNSRE---QTNQSLRKGKKKK-RWHHEEEK---MGVLEEGGKGKEAAGSVRTEEVESRAY 334
E + +G++++ W EEE+ G E G+G+E G EE E
Sbjct: 932 GEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGE 991
Query: 335 ADPCSRRKKRQQQEEEDLNLEDRGEE 360
+ + + + EE+ E EE
Sbjct: 992 EEEGEEEGEEEGEGEEEGEGEGEEEE 1017
Score = 38.9 bits (89), Expect = 0.008
Identities = 35/159 (22%), Positives = 70/159 (44%), Gaps = 14/159 (8%)
Query: 191 KGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKR 250
+G+D G + + E + ++++ + EEE E E E + + ++
Sbjct: 940 EGED-GEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEE 998
Query: 251 RHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGV 310
+EG+ +E EG +G E+E+ GE+ + + +G++++ EE+
Sbjct: 999 GEEEGEGEEEGEG--EGEEEEE-------GEVEGEVEGEEGEGEGEEEEGEEEGEER--- 1046
Query: 311 LEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEE 349
E+ G+G+E + EE E Y + +RQ EE
Sbjct: 1047 -EKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEE 1084
Score = 38.5 bits (88), Expect = 0.010
Identities = 45/194 (23%), Positives = 80/194 (41%), Gaps = 18/194 (9%)
Query: 180 EAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAE 239
E +E+ R + ++ G + E ++ K +R ++EEE E + +E+ E E
Sbjct: 795 EGEEEETEGRGEEKEEGG---EVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEE 851
Query: 240 QNIRKSKKKKRRHQEGKVS--------DEREGTTKGNEKEDAAGTS----GLGELNSREQ 287
+ +++ EG+ +E EG +G E+ + G G GE +
Sbjct: 852 EEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGE 911
Query: 288 TNQSLRKGKKKKRWHHEEEKMGVLEEG-GKGKEAAGSVRTEEVESRAYADPCSRRKKRQQ 346
+ +GK ++ E E G EEG G+G++ G EE E + + ++
Sbjct: 912 GEEEEGEGKGEEEGE-EGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEE-GEGEGEEE 969
Query: 347 QEEEDLNLEDRGEE 360
E E E GEE
Sbjct: 970 GEGEGEEGEGEGEE 983
Score = 38.5 bits (88), Expect = 0.010
Identities = 30/126 (23%), Positives = 57/126 (45%), Gaps = 6/126 (4%)
Query: 201 QSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGK-VSD 259
+ E + +++ + ++EE E E + +E+ E+ + + +EG+ +
Sbjct: 976 EGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGE 1035
Query: 260 EREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKE 319
E EG +G E+E G GE N R + + +GK ++ E E+ EE K +
Sbjct: 1036 EEEGEEEGEEREK----EGEGEENRRNREEEEEEEGKYQETGEEENERQDG-EEYKKVSK 1090
Query: 320 AAGSVR 325
GSV+
Sbjct: 1091 IKGSVK 1096
Score = 38.1 bits (87), Expect = 0.013
Identities = 44/169 (26%), Positives = 71/169 (42%), Gaps = 22/169 (13%)
Query: 213 KRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDER--EGTTKGNEK 270
K + E E R D + ++ + +++K +G+ ER EG + EK
Sbjct: 640 KAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEK 699
Query: 271 EDAAGTSG-LGELNSREQ-----TNQSLRKGKKKKRW---------HHEEEKMGVLEEGG 315
E+ G E REQ NQ + +G +++ EEEK G +E G
Sbjct: 700 EEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEG 759
Query: 316 KGKEAAGSVRTEEVESRAYADPCSRRKKRQQQ----EEEDLNLEDRGEE 360
+G+E G EE E R + + +K +++ E E+ E RGEE
Sbjct: 760 EGEEVEGEREKEEGE-RKKEERAGKEEKGEEEGDQGEGEEEETEGRGEE 807
Score = 33.5 bits (75), Expect = 0.32
Identities = 40/180 (22%), Positives = 73/180 (40%), Gaps = 17/180 (9%)
Query: 206 PPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTT 265
P +K+KK++ E + TA ND +++ E +E +++ K K+ +G + T
Sbjct: 519 PVQKQKKQQTIGELTQDTALTENDDSDEYEEMSE--MKEGKACKQHVSQGIFMTQPATTI 576
Query: 266 KG---------NEKEDAAGTSGLG----ELNSREQTNQSLRKGKKKKRWHHEEEKMGVLE 312
+ EKE A + G G E+ + E+ N + G+K+K ++ E
Sbjct: 577 EAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEE-NVKVHGGRKEKTEILSDDLTDKAE 635
Query: 313 -EGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSRE 371
GK K + E + S + Q EE + +D+G +G +E
Sbjct: 636 VSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKE 695
Score = 32.0 bits (71), Expect = 0.93
Identities = 26/124 (20%), Positives = 48/124 (38%), Gaps = 9/124 (7%)
Query: 201 QSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDE 260
+ E + +++ + +EEEE + +E E E+ + +++ + EG E
Sbjct: 998 EGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEG----E 1053
Query: 261 REGTTKGNEKEDAAGTSGLGELNSREQTNQSLRK-----GKKKKRWHHEEEKMGVLEEGG 315
+ E+E+ GE + Q + +K G K H +K V G
Sbjct: 1054 ENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQG 1113
Query: 316 KGKE 319
GKE
Sbjct: 1114 NGKE 1117
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 53.5 bits (127), Expect = 3e-07
Identities = 66/290 (22%), Positives = 123/290 (42%), Gaps = 11/290 (3%)
Query: 91 QIRSLSKETTRYNHPKPNLLYQKFVKMATLTSGGEKPNKDLESCSDDDNQGSKSPKILTD 150
Q ++ KE R + +K + L +G + +K ES + + KS K+ D
Sbjct: 230 QKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKS-KVTVD 288
Query: 151 EMLLQACEGR----TAHKAARLGITMKA-KLARLEAQEQAFLARLKGQDPGAPQLQSESK 205
++ A E + TA + G K K + +E+ + KG + E+
Sbjct: 289 TGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEAL 348
Query: 206 PPKKKKKKRRQKEEEEATAS-ERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGT 264
K++++R+++EEEE E +A K E EQ R+ KK+K + ++ ++ E +
Sbjct: 349 AKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLL 408
Query: 265 TKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSV 324
TK +++E A +L + + KKR +E++K + + + KE + S+
Sbjct: 409 TK-SQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESM 467
Query: 325 R-TEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSREQS 373
VE P + EE+ + ED G + W S E++
Sbjct: 468 ELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDD--WEAMASDEET 515
Score = 42.4 bits (98), Expect = 7e-04
Identities = 57/296 (19%), Positives = 121/296 (40%), Gaps = 59/296 (19%)
Query: 126 KPNKDLESCSDDDNQGSKSPKILTDEMLL--QACEGRTAHKAARLGITMKAKL---ARLE 180
KP ++ S SDDD+ +K PK + + +G + I ++++
Sbjct: 128 KPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESG 187
Query: 181 AQEQAFLARLKGQ------------------DPGAPQLQSESKPPKKKKKKRRQKEEEEA 222
+ FL KGQ D + ++++ ++ +KK++ R+K +EE
Sbjct: 188 DESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEE- 246
Query: 223 TASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKV------------------------S 258
A R +++ E +++ K K+ +R+ +E V
Sbjct: 247 KAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAE 306
Query: 259 DEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVL---EEGG 315
D+ EG K +K+ G +E+ + +KG K +E + L EE
Sbjct: 307 DDNEGDKKKKDKKKKKG--------EKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQ 358
Query: 316 KGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSRE 371
K +E R EE+E++ + ++KR+++++++ ++R ++ + + RE
Sbjct: 359 KREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQRE 414
Score = 36.6 bits (83), Expect = 0.038
Identities = 43/184 (23%), Positives = 79/184 (42%), Gaps = 8/184 (4%)
Query: 123 GGEKPNKDL---ESCSDDDNQGSKSPKILTDEMLLQACEGRTAHKAARLGITMKAKL--- 176
G E P+KD + +D + K P+ L + + ++ E A + G+ K +
Sbjct: 430 GVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPP 489
Query: 177 ARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPE 236
E +E A L + A ++E K + ++ EEE E + DE+ E
Sbjct: 490 VEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEE 549
Query: 237 HAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGK 296
E+ +S+ + ++ KVSDE++ + K +K+ + S E +S + + R
Sbjct: 550 EEEEE-GESEGSEGDEEDEKVSDEKD-SGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYD 607
Query: 297 KKKR 300
K KR
Sbjct: 608 KAKR 611
Score = 35.4 bits (80), Expect = 0.084
Identities = 46/204 (22%), Positives = 81/204 (39%), Gaps = 34/204 (16%)
Query: 185 AFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEE-------------EATASERNDAD 231
A A ++G Q +SK KKK+KK++ +E+ + ++R
Sbjct: 21 ALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVA 80
Query: 232 EKHPEHAEQNIRKSKKKKRRHQEGKV-------SDEREGTTKGNEKEDAAGTSGLGELNS 284
K E+ E+ SK KK++ Q+GK S+E E ++K +
Sbjct: 81 VKPTENNEEEF-TSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDD 139
Query: 285 REQTNQSLRKGKKK-----KRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCS 339
+ N+ +K K K K+W EE +E K S ES +D
Sbjct: 140 DDDFNKLPKKAKGKAQKSNKKWDGSEE-----DEDNSKKIKERSRINSSGESGDESDEFL 194
Query: 340 RRKKRQQQEEEDL---NLEDRGEE 360
+ +K Q++ +++ N+E E+
Sbjct: 195 QSRKGQKKNQKNKPGPNIESGNED 218
Score = 31.6 bits (70), Expect = 1.2
Identities = 39/198 (19%), Positives = 74/198 (37%), Gaps = 10/198 (5%)
Query: 170 ITMKAKLARLEAQEQAFLARLKGQDPGAPQLQSESKP---PKKKKKKRRQKEEEEATASE 226
+T + AR A+ L + +G + + + +P KK+KK +Q E +E + S
Sbjct: 408 LTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESM 467
Query: 227 RNDAD----EKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGEL 282
A E+ E+ + ++ E D+ E E E G E+
Sbjct: 468 ELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEV 527
Query: 283 NSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRK 342
+ + + +++ EEE+ EG +G E V E+ + S+
Sbjct: 528 KENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEM 587
Query: 343 KRQQQEEEDLNLEDRGEE 360
+ + D +DR +E
Sbjct: 588 SSDSEYDSD---DDRTKE 602
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 52.8 bits (125), Expect = 5e-07
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 26/227 (11%)
Query: 172 MKAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDAD 231
++ + ++ QE+ + K +L+ + K +++KK R Q+E+ + + + +
Sbjct: 264 LREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQE 323
Query: 232 EKHPEHAEQNIRKSKK-----KKRRHQEGKVSDEREGTTKGNEK-----EDAAGTSGLGE 281
EK E E+ R+ ++ K+ R QE K+ D+ E + +E+ E + E
Sbjct: 324 EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE 383
Query: 282 LNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRR 341
+ Q + +R+ +KK R EEE M EE + K+ EE E + P +
Sbjct: 384 QEEKMQEEERIREREKKMR--EEEETMREQEEKMQ-KQEENMWEQEEKEWQQQRLPEQKE 440
Query: 342 K-----KRQQQEEEDLNLEDR--------GEETFRWWNQGSREQSMQ 375
K K Q+QEE+ E++ G+E W + REQ Q
Sbjct: 441 KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQ 487
Score = 44.7 bits (104), Expect = 1e-04
Identities = 43/197 (21%), Positives = 87/197 (44%), Gaps = 24/197 (12%)
Query: 189 RLKGQDPGAPQLQSESKPPKKK-KKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKK 247
R+ QD + + + KK +++ + +EE++ E+ D++ E+ +R+ +K
Sbjct: 508 RMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREK 567
Query: 248 KKR------RHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRW 301
K R R QE K+ ++ E + EK + E + Q + +++K W
Sbjct: 568 KMREEEEMMREQEEKMQEQEEKMREQEEK--------MWEQEEKMQEQEEKMWEQEEKMW 619
Query: 302 HHEEE-KMG-----VLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLE 355
EEE KM + E+ K +E + +E + R + ++++ Q +EE + +
Sbjct: 620 EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQ 679
Query: 356 DRGEETFRWWNQGSREQ 372
EE + + REQ
Sbjct: 680 ---EEKMQGQEEKMREQ 693
Score = 42.4 bits (98), Expect = 7e-04
Identities = 29/167 (17%), Positives = 79/167 (47%), Gaps = 5/167 (2%)
Query: 209 KKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGN 268
++++K+ ++EEE E +++ ++ +++K + QE K+ ++ E +
Sbjct: 563 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 622
Query: 269 EKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEE 328
E++ + + Q + +++++ +EEKM EE +G+E +R +E
Sbjct: 623 EEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE--KMREQE 680
Query: 329 VESRAYADPCSRRKKRQQQEEEDLNLEDR---GEETFRWWNQGSREQ 372
+ + + ++++ + +EE + ++ G+E W + RE+
Sbjct: 681 EKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREK 727
Score = 41.2 bits (95), Expect = 0.002
Identities = 40/171 (23%), Positives = 78/171 (45%), Gaps = 15/171 (8%)
Query: 180 EAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAE 239
E +E+ + K Q+ + E K +++++ + Q++EE E +++ +
Sbjct: 592 EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQ 651
Query: 240 QNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKK 299
+ + +++K R QE K+ + E + EK E REQ + +G+++K
Sbjct: 652 EEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQ------EEKMREQEEKM--RGQEEK 703
Query: 300 RWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEE 350
W +EEKM EE G+E +R +E R D + ++R + EE
Sbjct: 704 MW-GQEEKMWGQEEKMWGQE---EMREKEERIR---DQKEKMQERLPEHEE 747
Score = 40.4 bits (93), Expect = 0.003
Identities = 43/191 (22%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
Query: 201 QSESKPPKKKKKKRRQKE---EEEATASERNDA---DEKHPEHAEQNIRKSKK-----KK 249
+ E K K+++K RQ+E E+E E+ + EK E+ +R+ +K KK
Sbjct: 245 EQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKK 304
Query: 250 RRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMG 309
R QE ++ ++ E + EK + + + +R+ ++K R +EE+M
Sbjct: 305 LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR--DQEERMW 362
Query: 310 VLEEGGKGKEAAGSVRT---EEVESRAYADPCSRRKKRQQQEEEDLNLEDR--GEETFRW 364
+E + KE + E+ E + R+K+ ++EEE + ++ ++
Sbjct: 363 EQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 422
Query: 365 WNQGSREQSMQ 375
W Q +E Q
Sbjct: 423 WEQEEKEWQQQ 433
Score = 38.1 bits (87), Expect = 0.013
Identities = 44/203 (21%), Positives = 94/203 (46%), Gaps = 17/203 (8%)
Query: 171 TMKAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQK-EEEEATASERND 229
TM+ + +++ QE+ + + + Q + P +K+K ++K +E+E E+ +
Sbjct: 407 TMREQEEKMQKQEENMWEQEE------KEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 460
Query: 230 ADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTN 289
E Q + +++K R QE ++ E+E + E++ + E + R +
Sbjct: 461 KIRDQEEMWGQEKKMWRQEKMREQEDQMW-EQEEKMRDQEQKMWDQEERMWEQDERLREK 519
Query: 290 QSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEE 349
+ R ++KK W EE+ + E K +E +T + E + + R ++++ +EE
Sbjct: 520 EE-RMREQKKMWQQEEK----MREEKKTQEQ--EKKTWDQEEKMREEERMREREKKMREE 572
Query: 350 EDLNLEDRGEETFRWWNQGSREQ 372
E++ E EE + + REQ
Sbjct: 573 EEMMREQ--EEKMQEQEEKMREQ 593
Score = 37.7 bits (86), Expect = 0.017
Identities = 54/210 (25%), Positives = 87/210 (41%), Gaps = 18/210 (8%)
Query: 175 KLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKH 234
K E QE+ RL + QL + K ++ K + + T E E+
Sbjct: 186 KKKNAELQEKL---RLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 242
Query: 235 PEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNS--REQTNQSL 292
E+ IRK ++K R +E E+EG + E++ L E REQ + L
Sbjct: 243 LREQEKKIRKQEEKMWRQEERL--REQEGKMREQEEKMRRQEKRLREQEKELREQ-EKEL 299
Query: 293 RKGKK----KKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQE 348
R+ KK +++ +EEKM EE + +E + E + + +K R Q+E
Sbjct: 300 REQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359
Query: 349 ---EEDLNL---EDRGEETFRWWNQGSREQ 372
E+D L E+R E + W Q + Q
Sbjct: 360 RMWEQDERLREKEERMREQEKMWEQEEKMQ 389
Score = 37.7 bits (86), Expect = 0.017
Identities = 37/186 (19%), Positives = 85/186 (45%), Gaps = 16/186 (8%)
Query: 199 QLQSESKPPKKKKKKRRQK----EEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQE 254
++ + K +++K R Q+ E+EE + ++ EQ+ R +K++R ++
Sbjct: 467 EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQ 526
Query: 255 GKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHE-----EEKMG 309
K+ + E + + ++ + E RE+ + +R+ +KK R E EEKM
Sbjct: 527 KKMWQQEEKMREEKKTQEQEKKTWDQEEKMREE--ERMREREKKMREEEEMMREQEEKMQ 584
Query: 310 VLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGS 369
EE K +E + +E + + + ++++ ++EE+ ++++ E W Q
Sbjct: 585 EQEE--KMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEE---MMWEQEE 639
Query: 370 REQSMQ 375
+ Q +
Sbjct: 640 KMQEQE 645
Score = 32.3 bits (72), Expect = 0.71
Identities = 24/128 (18%), Positives = 62/128 (48%), Gaps = 6/128 (4%)
Query: 178 RLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEH 237
+++ QE+ + + ++ + + +++++K R++EE+ E+ E+ +
Sbjct: 626 KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQG 685
Query: 238 AEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKK 297
E+ +R+ +++K R QE K+ + E EK G E+ +E+ + ++ +
Sbjct: 686 QEEKMRE-QEEKMRGQEEKMWGQEEKMWGQEEK-----MWGQEEMREKEERIRDQKEKMQ 739
Query: 298 KKRWHHEE 305
++ HEE
Sbjct: 740 ERLPEHEE 747
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 52.8 bits (125), Expect = 5e-07
Identities = 46/199 (23%), Positives = 93/199 (46%), Gaps = 17/199 (8%)
Query: 176 LARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERN-----DA 230
L R E + L+ Q+ G L+ E + +++++++ KEE++ ER D
Sbjct: 1353 LRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDR 1412
Query: 231 DEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQ--- 287
D K E +Q R+ + +K R +E +V +E K E+E + EQ
Sbjct: 1413 DRKFREEEQQLSRQERDRKFREEEQQVR-RQERERKFLEEEQQLRQERHRKFREEEQLLQ 1471
Query: 288 --TNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQ 345
Q L + ++ +++ EE+++ E K +E +R++E E + + ++++
Sbjct: 1472 EREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQ--ELRSQEPERKFLEEEQQLHRQQR 1529
Query: 346 Q----QEEEDLNLEDRGEE 360
Q QEE+ L ++RG++
Sbjct: 1530 QRKFLQEEQQLRRQERGQQ 1548
Score = 48.9 bits (115), Expect = 7e-06
Identities = 46/203 (22%), Positives = 93/203 (45%), Gaps = 24/203 (11%)
Query: 173 KAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADE 232
+ ++ RLE QE+ RLK ++P + Q K ++++++++Q E+ E+ E
Sbjct: 604 REEVERLE-QEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662
Query: 233 KHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSL 292
+ E EQ +++ +++RR QE +++E + + K S + + + ++
Sbjct: 663 EEEERLEQRLKREHEEERREQE--LAEEEQEQARERIK------SRIPKWQWQLESEADA 714
Query: 293 RKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDL 352
R+ K R +E + E+ K + ++ +E E R RQQQEE
Sbjct: 715 RQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEE----------RAHRQQQEE--- 761
Query: 353 NLEDRGEETFRWWNQGSREQSMQ 375
E R + T++W + E+ Q
Sbjct: 762 --EQRRDFTWQWQAEEKSERGRQ 782
Score = 48.5 bits (114), Expect = 1e-05
Identities = 40/172 (23%), Positives = 81/172 (47%), Gaps = 21/172 (12%)
Query: 199 QLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVS 258
Q + E ++++K+RRQ++E + E+ +E+ E+ R+ ++++R++++ K
Sbjct: 907 QEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKL 966
Query: 259 DEREGTTKGNEKEDAAGTSGLGELNSREQTNQS----LRKGKKKKR---WHHEEEKMGVL 311
++E G E E + E+ Q LR+ ++K+R W + K L
Sbjct: 967 QQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026
Query: 312 EEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDR---GEE 360
++ E +R E + R + ++RQ +EEE+L E+ GEE
Sbjct: 1027 QQ-----EEEQLLREEREKRRL------QERERQYREEEELQQEEEQLLGEE 1067
Score = 47.8 bits (112), Expect = 2e-05
Identities = 43/173 (24%), Positives = 84/173 (48%), Gaps = 25/173 (14%)
Query: 200 LQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSD 259
LQ E + +++++++R+++E+E E +E+ + EQ +R+ ++K+RR
Sbjct: 906 LQEEEEELQREEREKRRRQEQERQYRE----EEQLQQEEEQLLREEREKRRRQ------- 954
Query: 260 EREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKE 319
ERE + ++K LGE + + + +K ++++ EEE++ + EE K
Sbjct: 955 ERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQL-LREEREK--- 1010
Query: 320 AAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSREQ 372
R + R Y R+K QQEEE L E+R + + + RE+
Sbjct: 1011 -----RRRQEWERQY-----RKKDELQQEEEQLLREEREKRRLQERERQYREE 1053
Score = 46.2 bits (108), Expect = 5e-05
Identities = 55/243 (22%), Positives = 109/243 (44%), Gaps = 19/243 (7%)
Query: 125 EKPNKDLESCSDDDNQGSKSPKILTDEMLLQACEGRTAHKAAR--LGITMKAKLARLEAQ 182
E+ K LE + + + K +E LLQ E + H+ R + + +L R E
Sbjct: 1443 ERERKFLEE--EQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERD 1500
Query: 183 EQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASE-----RNDADEKHPEH 237
+ L+ Q+P L+ E + +++++++ +EE++ E R D D K E
Sbjct: 1501 RKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFRE- 1559
Query: 238 AEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKK 297
E+ +R+ +++++ ++ + R K +E + R++ Q LR+ +
Sbjct: 1560 -EEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD 1618
Query: 298 KKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDR 357
+K E+E++ L+E +E R E +P RR++R+QQ D + + R
Sbjct: 1619 RK--FREDEQL--LQE----REEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFR 1670
Query: 358 GEE 360
EE
Sbjct: 1671 EEE 1673
Score = 45.4 bits (106), Expect = 8e-05
Identities = 45/170 (26%), Positives = 82/170 (48%), Gaps = 19/170 (11%)
Query: 199 QLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHP----EHAEQNIRKSKKKKRRHQE 254
QLQ E + ++++++R+++E E + +K E E+ R+ ++KK R +E
Sbjct: 935 QLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEE 994
Query: 255 GKVSDE----REGTTKGNEKEDAAGTSGLGELNSREQT----NQSLRKGKKKKRWHHEEE 306
+E RE K +E EL E+ + R+ ++++R + EEE
Sbjct: 995 ELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEE 1054
Query: 307 KMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLED 356
++ EE G+E + R +E+E R Y R+++ QQEEE L E+
Sbjct: 1055 ELQQEEEQLLGEERE-TRRRQELE-RQY-----RKEEELQQEEEQLLREE 1097
Score = 44.7 bits (104), Expect = 1e-04
Identities = 40/193 (20%), Positives = 89/193 (46%), Gaps = 10/193 (5%)
Query: 180 EAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAE 239
E Q+Q L R + + + E + ++++++RR+++EE R + +E+ E
Sbjct: 293 EEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERR----E 348
Query: 240 QNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKK 299
Q +R+ ++++RR Q+ + E E + +E + + Q LR+ ++ +
Sbjct: 349 QQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 408
Query: 300 RWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGE 359
R E+++ ++ + ++ E E + + +R KR+Q+E D R E
Sbjct: 409 R----EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRD--WLKREE 462
Query: 360 ETFRWWNQGSREQ 372
ET R + ++Q
Sbjct: 463 ETERHEQERRKQQ 475
Score = 44.7 bits (104), Expect = 1e-04
Identities = 42/177 (23%), Positives = 84/177 (47%), Gaps = 25/177 (14%)
Query: 199 QLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVS 258
QL+ E + ++++ +R Q+ E R +E+H + EQ R+ ++ KR +E +
Sbjct: 400 QLRREQQLRREQQLRREQQLRREQQL-RREQEEERHEQKHEQE-RREQRLKREQEERRDW 457
Query: 259 DEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGK 318
+RE T+ +E+E R+Q + ++ ++++RW EE+ E + +
Sbjct: 458 LKREEETERHEQE------------RRKQQLKRDQEEERRERWLKLEEE----ERREQQE 501
Query: 319 EAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSREQSMQ 375
+R E+ E R ++ ++Q+EEE L R E+ R + REQ ++
Sbjct: 502 RREQQLRREQEERR-------EQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLK 551
Score = 44.3 bits (103), Expect = 2e-04
Identities = 40/194 (20%), Positives = 82/194 (42%), Gaps = 12/194 (6%)
Query: 178 RLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEH 237
R + +E+ + K Q L E + ++++++++ +EEEE E E+ +
Sbjct: 952 RRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKR 1011
Query: 238 AEQNIRKSKKKK-----------RRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSRE 286
Q + +KK R +E + ERE + E+ LGE
Sbjct: 1012 RRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETR 1071
Query: 287 QTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQ 346
+ + R+ +K++ EEE++ + EE K + + E E + R++R++
Sbjct: 1072 RRQELERQYRKEEELQQEEEQL-LREEPEKRRRQERERQCREEEELQQEEEQLLREEREK 1130
Query: 347 QEEEDLNLEDRGEE 360
+ ++L + R EE
Sbjct: 1131 RRRQELERQYREEE 1144
Score = 43.9 bits (102), Expect = 2e-04
Identities = 40/176 (22%), Positives = 80/176 (45%), Gaps = 15/176 (8%)
Query: 182 QEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQN 241
QE+ RLK Q+ +LQ + +++ RR++EE +R + E EQ
Sbjct: 511 QEERREQRLKRQEE-EERLQQRLR---SEQQLRREQEERREQLLKREEEKRLEQERREQR 566
Query: 242 IRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRW 301
+++ ++++R + + R+ K ++E E+ EQ + R+ + K+
Sbjct: 567 LKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ--EERREQRLKREE 624
Query: 302 HHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDR 357
EE + +L+ + + +R E+ E RR++R ++EEE+ LE R
Sbjct: 625 PEEERRQQLLKSEEQEERRQQQLRREQQE---------RREQRLKREEEEERLEQR 671
Score = 43.9 bits (102), Expect = 2e-04
Identities = 53/231 (22%), Positives = 98/231 (42%), Gaps = 39/231 (16%)
Query: 146 KILTDEMLLQACEGRTAHKAARLGITMKAKLARLEAQEQAFLARLKGQDPGAPQLQSESK 205
K DE LLQ E + H+ R ++ FL PQL+ + +
Sbjct: 1620 KFREDEQLLQEREEQQLHRQER---------------DRKFLEE-------EPQLRRQER 1657
Query: 206 PPKKKKKKRRQKEEEEATASE-------RNDADEKHPEHAEQNIRKSKKKKRRHQEGKVS 258
+ + + R+ EEE E R + D K E EQ +R+ +++++ QE +
Sbjct: 1658 EQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREE-EQQLRRQERERKFLQEEQQL 1716
Query: 259 DEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGK 318
+E K E+E + +L +E+ + L +++ R EE+++ E K +
Sbjct: 1717 RRQELERKFREEEQLRQETEQEQLRRQERYRKILE--EEQLRPEREEQQLRRQERDRKFR 1774
Query: 319 EAAGSVRTEEVESRAYADPCSRR-----KKRQQQEEEDLNLEDRGEETFRW 364
E +R E E + + R+ + RQ++EE+ L + R + +RW
Sbjct: 1775 EEE-QLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQR-DGKYRW 1823
Score = 43.1 bits (100), Expect = 4e-04
Identities = 42/210 (20%), Positives = 97/210 (46%), Gaps = 19/210 (9%)
Query: 146 KILTDEMLLQACEGRTAHKAAR-LGITMKAKLARLEAQEQAFLARLKGQDPGAPQLQSES 204
K +E LLQ E + + R + + R + +E+ FL Q+ + Q
Sbjct: 1668 KFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFL-----QEEQQLRRQELE 1722
Query: 205 KPPKKKKKKRRQKEEEEATASERN----DADEKHPEHAEQNIRKSKKKKRRHQEGKVSDE 260
+ +++++ R++ E+E+ ER + ++ PE EQ +R+ ++ ++ +E ++ E
Sbjct: 1723 RKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQE 1782
Query: 261 REGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEA 320
RE +++ D E +E+ Q LR ++ ++ EEE++ + E+ +
Sbjct: 1783 REEQQLRSQESDRKFREE--EQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQR---- 1836
Query: 321 AGSVRTEEVESRAYADPCSRRKKRQQQEEE 350
+R E + + ++K +++E+E
Sbjct: 1837 ---LRQERDRQYRAEEQFATQEKSRREEQE 1863
Score = 42.7 bits (99), Expect = 5e-04
Identities = 41/192 (21%), Positives = 84/192 (43%), Gaps = 19/192 (9%)
Query: 199 QLQSESKPPKKKKKKR-----RQKEEEEATASERNDADEKH-PEHAEQNIRKSKKKKRRH 252
Q Q+E K + +++ R++ E + A ER +++ PE E+ R+ ++++R
Sbjct: 770 QWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREK 829
Query: 253 QEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEK----- 307
+ + +E + + ++ GL E R ++ + R +K RW EEE+
Sbjct: 830 ELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRR--DQKWRWQLEEERKRRRH 887
Query: 308 ----MGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFR 363
L+E + ++ EE++ + ++RQ +EEE L E+ E+ R
Sbjct: 888 TLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEE--EQLLR 945
Query: 364 WWNQGSREQSMQ 375
+ R Q +
Sbjct: 946 EEREKRRRQERE 957
Score = 42.4 bits (98), Expect = 7e-04
Identities = 39/194 (20%), Positives = 87/194 (44%), Gaps = 18/194 (9%)
Query: 182 QEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQN 241
+E+ L +L+ Q+ + + E + + +++++ ++++EE ER + E+ E E+
Sbjct: 273 EEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE----ERREQQEERREQQER- 327
Query: 242 IRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRW 301
R+ ++++R Q + +ER E+E+ L E+ Q LR+ ++ +R
Sbjct: 328 -REQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE 386
Query: 302 HHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEET 361
+ + E +E +R E+ R+++Q + E+ L E E
Sbjct: 387 QQLRREQQLRREQQLRREQ--QLRREQ----------QLRREQQLRREQQLRREQEEERH 434
Query: 362 FRWWNQGSREQSMQ 375
+ Q REQ ++
Sbjct: 435 EQKHEQERREQRLK 448
Score = 42.4 bits (98), Expect = 7e-04
Identities = 36/161 (22%), Positives = 71/161 (44%), Gaps = 3/161 (1%)
Query: 199 QLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVS 258
Q + E ++++K+RRQ+ E + + +E+ E+ R+ ++++R+++E +
Sbjct: 997 QQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEEL 1056
Query: 259 DEREGTTKGNEKEDAAGTSGLGELNSREQTNQS---LRKGKKKKRWHHEEEKMGVLEEGG 315
+ E G E+E + E+ Q L + + +KR E E+ EE
Sbjct: 1057 QQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEEL 1116
Query: 316 KGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLED 356
+ +E E R + R ++ QQEEE L E+
Sbjct: 1117 QQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREE 1157
Score = 42.4 bits (98), Expect = 7e-04
Identities = 46/195 (23%), Positives = 89/195 (45%), Gaps = 26/195 (13%)
Query: 189 RLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEE--------ATASERNDAD--------- 231
R + +D P+ + + +K+ K+R +K +EE R + D
Sbjct: 1285 RWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQL 1344
Query: 232 ----EKHPEHAEQNIRKSKKKKRRHQE-GKVSDEREGTTKGNEKEDAAGTSGLGELNSRE 286
E+ P ++ RK ++++ RHQE G+ E E + E+E +L +E
Sbjct: 1345 LQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERE-RKFLKEEQQLRCQE 1403
Query: 287 QTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQ 346
+ Q LR+ + +K + EE+++ E K +E VR +E E + + R++R +
Sbjct: 1404 R-EQQLRQDRDRK-FREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHR 1461
Query: 347 Q-EEEDLNLEDRGEE 360
+ EE+ L++R E+
Sbjct: 1462 KFREEEQLLQEREEQ 1476
Score = 42.4 bits (98), Expect = 7e-04
Identities = 47/217 (21%), Positives = 97/217 (44%), Gaps = 32/217 (14%)
Query: 146 KILTDEMLLQACEGRTAHKAAR-LGITMKAKLARLEAQEQAFLA---RLKGQDPGAPQLQ 201
K +E L Q E + + R ++ + R + QE+ F+ +L+ Q+ G QL+
Sbjct: 1556 KFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQE-GQQQLR 1614
Query: 202 SESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRH-QEGKVSDE 260
E ++ ++ Q+ EE+ R + D K E Q R+ ++++ RH ++ K +E
Sbjct: 1615 QERDRKFREDEQLLQEREEQQL--HRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREE 1672
Query: 261 REGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEA 320
+ +G E Q LR+ ++ +++ EE+++ E K +
Sbjct: 1673 EQLLQEGEE--------------------QQLRRQERDRKFREEEQQLRRQERERKFLQE 1712
Query: 321 AGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDR 357
+R +E+E + + + RQ+ E+E L ++R
Sbjct: 1713 EQQLRRQELERKFREE----EQLRQETEQEQLRRQER 1745
Score = 41.2 bits (95), Expect = 0.002
Identities = 37/181 (20%), Positives = 84/181 (46%), Gaps = 21/181 (11%)
Query: 201 QSESKPPKKKKKKRR--QKEEEEATASERND--ADEKHPEHAEQNIRKSKKKKRRHQEGK 256
+ E K +++ +++R Q+EEE+ ER + + + E +Q +R+ ++ +R+ +E +
Sbjct: 255 KEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314
Query: 257 VSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGK 316
+ E + +E E+ Q LR+ ++++R E+++ +E +
Sbjct: 315 REQQEERREQQERRE-----------QQEERREQQLRREQEERR----EQQLRREQEEER 359
Query: 317 GKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLED--RGEETFRWWNQGSREQSM 374
++ + EE + R+++Q + E+ L E R E+ R Q REQ +
Sbjct: 360 REQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 419
Query: 375 Q 375
+
Sbjct: 420 R 420
Score = 40.4 bits (93), Expect = 0.003
Identities = 49/228 (21%), Positives = 98/228 (42%), Gaps = 22/228 (9%)
Query: 150 DEMLLQACEGRTAHKAARLGITMKAKLARL--EAQEQAFLARLKGQDPGAPQLQSESKPP 207
+E LQ+C+G + + +L L + +E+ R + QD Q E +
Sbjct: 189 EEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDR---VFQEEEEKE 245
Query: 208 KKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKG 267
+K++ +KEEE+ E ++ + E+ +RK ++++ R + + +++ +
Sbjct: 246 WRKRETVLRKEEEK--LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRRE 303
Query: 268 NEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTE 327
+ E REQ Q R+ ++++R EE + L + + R +
Sbjct: 304 QQLRRKQ------EEERREQ--QEERREQQERREQQEERREQQLRREQEERREQQLRREQ 355
Query: 328 EVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSREQSMQ 375
E E R ++ R++QEEE + R E+ R Q REQ ++
Sbjct: 356 EEERR-------EQQLRREQEEERREQQLRREQQLRREQQLRREQQLR 396
Score = 40.4 bits (93), Expect = 0.003
Identities = 42/199 (21%), Positives = 88/199 (44%), Gaps = 16/199 (8%)
Query: 180 EAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDA---DEKHPE 236
+ Q Q L L G+ + E + + +++ R EEE+ E+ +A D K E
Sbjct: 1260 DRQSQQDLQHLLGEQQ---ERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQE 1316
Query: 237 HAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGK 296
+ + ++K+RR + + E E + E++ + R+ + LR +
Sbjct: 1317 EKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLR-----RQERDRKFREEELRHQE 1371
Query: 297 KKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLED 356
+ +++ EE+++ E K + +R +E E + D R ++ ++EE+ L+ ++
Sbjct: 1372 QGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQD----RDRKFREEEQQLSRQE 1427
Query: 357 RGEETFRWWNQGSREQSMQ 375
R + FR Q R Q +
Sbjct: 1428 R-DRKFREEEQQVRRQERE 1445
Score = 39.7 bits (91), Expect = 0.004
Identities = 35/165 (21%), Positives = 77/165 (46%), Gaps = 20/165 (12%)
Query: 208 KKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKG 267
++++K+RR + E+ +++ + E+ +++ +++KRR QE + E +
Sbjct: 879 EEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQ 938
Query: 268 NEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTE 327
E E RE+ + R+ ++++R + +++K+ EE G+E
Sbjct: 939 EE-----------EQLLREEREK--RRRQERERQYRKDKKLQQKEEQLLGEE-------P 978
Query: 328 EVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSREQ 372
E R + R ++ QQEEE L E+R + + W + R++
Sbjct: 979 EKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKK 1023
Score = 39.7 bits (91), Expect = 0.004
Identities = 38/182 (20%), Positives = 78/182 (42%), Gaps = 24/182 (13%)
Query: 201 QSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDE 260
Q E + +++++KRRQ+ E + E ++ + +++ R K + ++ +
Sbjct: 1178 QEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRD 1237
Query: 261 REGTTKGNEKEDAAGTSG---------------LGELNSREQTNQSLRKGKKKKRWHHEE 305
+ KG E E LGE R++ Q R+ +++ R EE
Sbjct: 1238 NKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDR-EQERRRWQQRDRHFPEE 1296
Query: 306 EKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQE----EEDLNLEDRGEET 361
E++ E + KEA R + E + + +++RQ+ + EE+ L++R E+
Sbjct: 1297 EQL----EREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQP 1352
Query: 362 FR 363
R
Sbjct: 1353 LR 1354
Score = 38.9 bits (89), Expect = 0.008
Identities = 36/166 (21%), Positives = 74/166 (44%), Gaps = 25/166 (15%)
Query: 199 QLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVS 258
Q + E ++ +K+RRQ+ E + E +E EQ +R+ ++K+RR + +
Sbjct: 1087 QQEEEQLLREEPEKRRRQERERQCREEEELQQEE------EQLLREEREKRRRQELERQY 1140
Query: 259 DEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGK 318
E E + E+ L E + + + R+ ++++ EEE++ E+ + +
Sbjct: 1141 REEEEVQQEEEQL-------LREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQ 1193
Query: 319 EAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFRW 364
E R EE R+K++Q+ +ED R + ++W
Sbjct: 1194 ERERQYREEE--------ELQRQKRKQRYRDED----QRSDLKWQW 1227
Score = 37.7 bits (86), Expect = 0.017
Identities = 31/162 (19%), Positives = 71/162 (43%), Gaps = 14/162 (8%)
Query: 210 KKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNE 269
++K+ R +E R + D++ E ++ + + ++RR + + E + +E
Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE 156
Query: 270 KEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLE--EGGKGKEAAGSVRTE 327
K++ L R++ + ++++ W EE+ E + KG E E
Sbjct: 157 KQE--------RLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEE 208
Query: 328 EVESRAYADPCSRRKKRQQQEEEDLNLEDR--GEETFRWWNQ 367
++ R + RRK R++++++ +DR EE + W +
Sbjct: 209 QLRRRELLE--LRRKGREEKQQQRRERQDRVFQEEEEKEWRK 248
Score = 35.0 bits (79), Expect = 0.11
Identities = 46/237 (19%), Positives = 100/237 (42%), Gaps = 33/237 (13%)
Query: 167 RLGITMKAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQK--EEEEATA 224
RL ++++ QE+ LK ++ + + + K+++++RR + + EE
Sbjct: 527 RLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERR 586
Query: 225 SERNDADEKHPEHAEQNIRK---------SKKKKRRHQEGKVSDEREGTTKGNEKEDAAG 275
+R +++ E EQ +++ ++++R +E + R+ K E+E+
Sbjct: 587 QQRLKREQE--ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ 644
Query: 276 TSGLGELNSR-----EQTNQSLRKGKKKKRWHHEEEKMGVL--EEGGKGKEAAGS----- 323
E R ++ + R ++ KR H EE + L EE + +E S
Sbjct: 645 QQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKW 704
Query: 324 -----VRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSREQSMQ 375
+ +S+ Y+ P + +R++QE+E+ + R E+ W + R Q
Sbjct: 705 QWQLESEADARQSKVYSRPRKQEGQRRRQEQEE---KRRRRESELQWQEEERAHRQQ 758
Score = 35.0 bits (79), Expect = 0.11
Identities = 43/173 (24%), Positives = 73/173 (42%), Gaps = 16/173 (9%)
Query: 208 KKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKG 267
+++++ R EEEE E E+ Q + + +K+ Q+ + RE K
Sbjct: 1045 ERERQYR---EEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKR 1101
Query: 268 NEKEDAAGTSGLGELNSREQTNQSLRKGKKKKR-----WHHEEEKMGVLEEGGKGKEAAG 322
+E EL E+ Q LR+ ++K+R + EE+ EE +E
Sbjct: 1102 RRQERERQCREEEELQQEEE--QLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPE 1159
Query: 323 SVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSREQSMQ 375
R +E+E R Y R ++ QQEEE L E++ + Q E+ +Q
Sbjct: 1160 KRRRQELE-RQY-----REEEELQQEEEQLLREEQEKRRQERERQYREEEELQ 1206
Score = 32.0 bits (71), Expect = 0.93
Identities = 29/123 (23%), Positives = 53/123 (43%), Gaps = 9/123 (7%)
Query: 146 KILTDEMLLQACEGRTAHKAARLG-ITMKAKLARLEAQEQAFLARLKGQDPGAPQLQSES 204
K +E L Q E + R G + + +LE QEQ Q Q ++
Sbjct: 1796 KFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQ- 1854
Query: 205 KPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGT 264
+K R++E+E E+ E+ + E++IR+ +K+++RH++ +EG
Sbjct: 1855 -------EKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGK 1907
Query: 265 TKG 267
G
Sbjct: 1908 GHG 1910
Score = 29.6 bits (65), Expect = 4.6
Identities = 41/209 (19%), Positives = 87/209 (41%), Gaps = 43/209 (20%)
Query: 146 KILTDEMLLQACEGRTAHKAARLGITMKAKLARLEAQEQAFLARLKGQDPGAPQLQSESK 205
K +E L Q E + R ++ + R E +EQ QL+ + +
Sbjct: 1724 KFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQ--------------QLRRQER 1769
Query: 206 PPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKR---RHQEGKVSDERE 262
+K +++ + ++E E ++D K E E+ +R+ +++++ + ++GK E E
Sbjct: 1770 D-RKFREEEQLRQEREEQQLRSQESDRKFRE--EEQLRQEREEQQLRPQQRDGKYRWEEE 1826
Query: 263 GTTKGNEKEDAAGTSGLGELNSREQ-TNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAA 321
+ E+E + + EQ Q + ++++ W EE+K + +E
Sbjct: 1827 -QLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQK--------RRQERE 1877
Query: 322 GSVRTEEVESRAYADPCSRRKKRQQQEEE 350
+R E + +RQQ+EE+
Sbjct: 1878 RKLREEHI-------------RRQQKEEQ 1893
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 52.4 bits (124), Expect = 7e-07
Identities = 56/228 (24%), Positives = 102/228 (44%), Gaps = 25/228 (10%)
Query: 166 ARLGITMKAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATAS 225
+R G ++K +R +Q ++ + K + P + +S S K + K + + EE+
Sbjct: 222 SRSGSRSRSK-SRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKI--- 277
Query: 226 ERNDADEKHPEHAEQNIRKSKKKKR-RHQEGKVSDEREGT-TKGNEKEDAAGTS------ 277
+N+ + P+ + KSK K R R QE +V +E+ G+ ++G +E + S
Sbjct: 278 -QNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRS 336
Query: 278 -GLGELNSREQT-NQSLRKGKKKKRWHHEEEKMG------VLEEGGKGKEAAGSVRTEEV 329
G SR ++ ++ RKG+K+ R + G K AGS + ++
Sbjct: 337 KGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKK 396
Query: 330 E----SRAYADPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSREQS 373
E S++ + S K+R+ + E E RGE NQ +R +S
Sbjct: 397 EDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRS 444
Score = 44.7 bits (104), Expect = 1e-04
Identities = 39/217 (17%), Positives = 93/217 (42%), Gaps = 6/217 (2%)
Query: 132 ESCSDDDNQGSKSPKILTDEMLLQACEGRTAHKAARLGITMKAKLARLEAQEQAFL---A 188
E ++DN G PK + + R+ + R+ + ++R +QE++ +
Sbjct: 275 EKIQNNDNVGK--PKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRS 332
Query: 189 RLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKK 248
R + + + +S SK K+K ++R +EE + + R+ ++ ++++ + K
Sbjct: 333 RSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSK 392
Query: 249 KRRHQEGKVSDERE-GTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEK 307
K++ ++ S R + E+E A S E + + ++ + + R + + +
Sbjct: 393 KKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKP 452
Query: 308 MGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKR 344
E + K A+ + + SR+ + SR + R
Sbjct: 453 NLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSR 489
Score = 32.7 bits (73), Expect = 0.55
Identities = 31/156 (19%), Positives = 61/156 (39%), Gaps = 17/156 (10%)
Query: 212 KKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKE 271
+K R E++ + R+ + + + R S+K + R K S + +
Sbjct: 168 RKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSK------SRSR 221
Query: 272 DAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVE- 330
+G+ + SR Q+ R K+K R +E+ GK + + E+++
Sbjct: 222 SRSGSRSRSKSRSRSQSRS--RSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQN 279
Query: 331 --------SRAYADPCSRRKKRQQQEEEDLNLEDRG 358
SR+ + S+ K R + +E + E RG
Sbjct: 280 NDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRG 315
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 52.4 bits (124), Expect = 7e-07
Identities = 51/220 (23%), Positives = 94/220 (42%), Gaps = 22/220 (10%)
Query: 158 EGRTAHKAARLGITMKAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQK 217
E R A A+ + + L Q++ L R + ++ + + E K+++ RRQ+
Sbjct: 734 ERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE-EEELARRKQEEALRRQR 792
Query: 218 EEEEATASERNDADEKHPEHAEQNI--RKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAG 275
E+E A +R + + + E A + + R+ ++++RR QE + + E K +E+ A
Sbjct: 793 EQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEA- 851
Query: 276 TSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYA 335
R LR ++ R HEEE+ K KE + E + R
Sbjct: 852 --------QRRLEENRLRMEEEAARLRHEEEER-------KRKELEVQRQKELMRQRQQQ 896
Query: 336 DPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSREQSMQ 375
RR ++QQQ+++ ++ T W Q S + Q
Sbjct: 897 QEALRRLQQQQQQQQLAQMKLPSSST---WGQQSNTTACQ 933
Score = 45.4 bits (106), Expect = 8e-05
Identities = 39/171 (22%), Positives = 76/171 (44%), Gaps = 9/171 (5%)
Query: 195 PGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNI--RKSKKKKRRH 252
P QLQ K K ++ R++ E A E ++ ++ I R+ +++++R
Sbjct: 715 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 774
Query: 253 QEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLE 312
+E +++ ++ ++E E R+Q ++LR+ ++++R EEE+ E
Sbjct: 775 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRR--EEEERRKQEE 832
Query: 313 EGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFR 363
K +E A EE E++ + + R + EEE L EE R
Sbjct: 833 LLRKQEEEAAKWAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKR 878
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 52.4 bits (124), Expect = 7e-07
Identities = 51/220 (23%), Positives = 94/220 (42%), Gaps = 22/220 (10%)
Query: 158 EGRTAHKAARLGITMKAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQK 217
E R A A+ + + L Q++ L R + ++ + + E K+++ RRQ+
Sbjct: 761 ERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE-EEELARRKQEEALRRQR 819
Query: 218 EEEEATASERNDADEKHPEHAEQNI--RKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAG 275
E+E A +R + + + E A + + R+ ++++RR QE + + E K +E+ A
Sbjct: 820 EQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEA- 878
Query: 276 TSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYA 335
R LR ++ R HEEE+ K KE + E + R
Sbjct: 879 --------QRRLEENRLRMEEEAARLRHEEEER-------KRKELEVQRQKELMRQRQQQ 923
Query: 336 DPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSREQSMQ 375
RR ++QQQ+++ ++ T W Q S + Q
Sbjct: 924 QEALRRLQQQQQQQQLAQMKLPSSST---WGQQSNTTACQ 960
Score = 45.4 bits (106), Expect = 8e-05
Identities = 39/171 (22%), Positives = 76/171 (44%), Gaps = 9/171 (5%)
Query: 195 PGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNI--RKSKKKKRRH 252
P QLQ K K ++ R++ E A E ++ ++ I R+ +++++R
Sbjct: 742 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 801
Query: 253 QEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLE 312
+E +++ ++ ++E E R+Q ++LR+ ++++R EEE+ E
Sbjct: 802 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRR--EEEERRKQEE 859
Query: 313 EGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFR 363
K +E A EE E++ + + R + EEE L EE R
Sbjct: 860 LLRKQEEEAAKWAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKR 905
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 52.4 bits (124), Expect = 7e-07
Identities = 51/220 (23%), Positives = 94/220 (42%), Gaps = 22/220 (10%)
Query: 158 EGRTAHKAARLGITMKAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQK 217
E R A A+ + + L Q++ L R + ++ + + E K+++ RRQ+
Sbjct: 740 ERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE-EEELARRKQEEALRRQR 798
Query: 218 EEEEATASERNDADEKHPEHAEQNI--RKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAG 275
E+E A +R + + + E A + + R+ ++++RR QE + + E K +E+ A
Sbjct: 799 EQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEA- 857
Query: 276 TSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYA 335
R LR ++ R HEEE+ K KE + E + R
Sbjct: 858 --------QRRLEENRLRMEEEAARLRHEEEER-------KRKELEVQRQKELMRQRQQQ 902
Query: 336 DPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSREQSMQ 375
RR ++QQQ+++ ++ T W Q S + Q
Sbjct: 903 QEALRRLQQQQQQQQLAQMKLPSSST---WGQQSNTTACQ 939
Score = 45.4 bits (106), Expect = 8e-05
Identities = 39/171 (22%), Positives = 76/171 (44%), Gaps = 9/171 (5%)
Query: 195 PGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNI--RKSKKKKRRH 252
P QLQ K K ++ R++ E A E ++ ++ I R+ +++++R
Sbjct: 721 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
Query: 253 QEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLE 312
+E +++ ++ ++E E R+Q ++LR+ ++++R EEE+ E
Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRR--EEEERRKQEE 838
Query: 313 EGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFR 363
K +E A EE E++ + + R + EEE L EE R
Sbjct: 839 LLRKQEEEAAKWAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKR 884
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 52.4 bits (124), Expect = 7e-07
Identities = 51/220 (23%), Positives = 94/220 (42%), Gaps = 22/220 (10%)
Query: 158 EGRTAHKAARLGITMKAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQK 217
E R A A+ + + L Q++ L R + ++ + + E K+++ RRQ+
Sbjct: 740 ERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE-EEELARRKQEEALRRQR 798
Query: 218 EEEEATASERNDADEKHPEHAEQNI--RKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAG 275
E+E A +R + + + E A + + R+ ++++RR QE + + E K +E+ A
Sbjct: 799 EQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEA- 857
Query: 276 TSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYA 335
R LR ++ R HEEE+ K KE + E + R
Sbjct: 858 --------QRRLEENRLRMEEEAARLRHEEEER-------KRKELEVQRQKELMRQRQQQ 902
Query: 336 DPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSREQSMQ 375
RR ++QQQ+++ ++ T W Q S + Q
Sbjct: 903 QEALRRLQQQQQQQQLAQMKLPSSST---WGQQSNTTACQ 939
Score = 45.4 bits (106), Expect = 8e-05
Identities = 39/171 (22%), Positives = 76/171 (44%), Gaps = 9/171 (5%)
Query: 195 PGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNI--RKSKKKKRRH 252
P QLQ K K ++ R++ E A E ++ ++ I R+ +++++R
Sbjct: 721 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
Query: 253 QEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLE 312
+E +++ ++ ++E E R+Q ++LR+ ++++R EEE+ E
Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRR--EEEERRKQEE 838
Query: 313 EGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFR 363
K +E A EE E++ + + R + EEE L EE R
Sbjct: 839 LLRKQEEEAAKWAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKR 884
>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
isoform 2 [Homo sapiens]
Length = 1153
Score = 52.0 bits (123), Expect = 9e-07
Identities = 40/160 (25%), Positives = 74/160 (46%), Gaps = 17/160 (10%)
Query: 124 GEKPNKDLESCSDDDNQGSKSPKILTDEMLLQACEGRTAHKAAR-----LGITMKAKLA- 177
G++ + L + SD+D ++ I+T+EM A K L I + LA
Sbjct: 753 GKRRHSSLPTESDEDIAPAQQVDIVTEEMPENALPSDEDDKDPNDPYRALDIDLDKPLAD 812
Query: 178 --RLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHP 235
+L Q+ K + P ++ +SK PKKK+KK ++KE D ++K
Sbjct: 813 SEKLPIQKHRNTETSKSPEKDVPMVEKKSKKPKKKEKKHKEKE---------RDKEKKKE 863
Query: 236 EHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAG 275
+ +++ + KKK R+ +E + +++ + E+AAG
Sbjct: 864 KEKKKSPKPKKKKHRKEKEERTKGKKKSKKQPPGSEEAAG 903
Score = 33.1 bits (74), Expect = 0.42
Identities = 36/143 (25%), Positives = 54/143 (37%), Gaps = 12/143 (8%)
Query: 180 EAQEQAFLARLKGQDPGAPQLQSE---SKPPKKKKKKRRQKEEEEATASERNDADEKHPE 236
E E A + +DP P + KP +K QK RN K PE
Sbjct: 780 EMPENALPSDEDDKDPNDPYRALDIDLDKPLADSEKLPIQKH--------RNTETSKSPE 831
Query: 237 HAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGK 296
+ K K KK + +E K ++ K EKE + + +E+ ++ K K
Sbjct: 832 KDVPMVEK-KSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEERTKGKKK 890
Query: 297 KKKRWHHEEEKMGVLEEGGKGKE 319
KK+ EE G + G +E
Sbjct: 891 SKKQPPGSEEAAGEPVQNGAPEE 913
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 51.2 bits (121), Expect = 1e-06
Identities = 56/249 (22%), Positives = 97/249 (38%), Gaps = 25/249 (10%)
Query: 121 TSGGEKPNKDLESCSDDDNQG-----SKSPKILTDEMLLQACEGRTAHKAARLGITMKAK 175
T G EKP KD+ S S D QG K + E ++++ GR A+ +
Sbjct: 586 TKGTEKP-KDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASG------SA 638
Query: 176 LARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHP 235
+ L QE + +D G + + K + K+++K ++ + ++ AD +
Sbjct: 639 CSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEK 698
Query: 236 EHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKG 295
++ KSKK+K+R ++ S + +G + E S R + S R+
Sbjct: 699 SSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRS 758
Query: 296 KKKKRWHHEEEKMGVLEEGG--------KGKEAAGSVRTEEVESRAYADPCSRRKKRQQQ 347
EE G +EGG G++ G + + RA SR R Q
Sbjct: 759 LPA-----EEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQP 813
Query: 348 EEEDLNLED 356
D + +D
Sbjct: 814 SSGDEDSDD 822
Score = 36.6 bits (83), Expect = 0.038
Identities = 15/35 (42%), Positives = 21/35 (60%)
Query: 24 LLKHGWTQGKGLGRKENGITQALRVTLKQDTHGVG 58
L KHGW G+GLG+ G T + + +K D G+G
Sbjct: 48 LQKHGWKLGQGLGKSLQGRTDPIPIVVKYDVMGMG 82
Score = 30.0 bits (66), Expect = 3.5
Identities = 30/175 (17%), Positives = 69/175 (39%), Gaps = 11/175 (6%)
Query: 191 KGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKR 250
+G P P S S P +++++ + + + +E + +K + + +K
Sbjct: 729 RGPKPEPPG--SGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKH 786
Query: 251 RHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGV 310
+ + S +R TK + + G+ +S + ++ L + K ++ EEE+
Sbjct: 787 KGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQ-KSPSQYSEEEEEEDS 845
Query: 311 LEEGGKGKEAAG--------SVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDR 357
E + + +G S R+ S A +D ++R ++ + DR
Sbjct: 846 GSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDR 900
>gi|117553584 adaptor-related protein complex 3, delta 1 subunit
isoform 1 [Homo sapiens]
Length = 1112
Score = 48.9 bits (115), Expect = 7e-06
Identities = 53/204 (25%), Positives = 86/204 (42%), Gaps = 25/204 (12%)
Query: 124 GEKPNKDLESCSDDDNQGSKSPKILTDEMLLQACEGRTAHKAAR-----LGITMKAKLA- 177
G++ + L + SD+D ++ I+T+EM A K L I + LA
Sbjct: 662 GKRRHSSLPTESDEDIAPAQQVDIVTEEMPENALPSDEDDKDPNDPYRALDIDLDKPLAD 721
Query: 178 --RLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHP 235
+L Q+ K + P ++ +SK PKKK+KK ++KE ++ E+ EK
Sbjct: 722 SEKLPIQKHRNTETSKSPEKDVPMVEKKSKKPKKKEKKHKEKERDK----EKKKEKEKKA 777
Query: 236 EHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKG 295
E + + + V +E EDA T GE + E +Q +
Sbjct: 778 EDLDFWLSTTPPPAPAPAPAPVPST-------DECEDAK-TEAQGEEDDAEGQDQDKKSP 829
Query: 296 KKKKRWHHEEEKMGVLEEGGKGKE 319
K KK+ H +E+ EE KGK+
Sbjct: 830 KPKKKKHRKEK-----EERTKGKK 848
Score = 32.3 bits (72), Expect = 0.71
Identities = 33/116 (28%), Positives = 51/116 (43%), Gaps = 13/116 (11%)
Query: 125 EKPNKDLESCSDDDNQGSKSPKILTDEMLLQACEGRTAHKAARLGITMKAKLARLEAQEQ 184
EK +K+ E + + K + L D L A A + T + + A+ EAQ
Sbjct: 757 EKKHKEKERDKEKKKEKEKKAEDL-DFWLSTTPPPAPAPAPAPVPSTDECEDAKTEAQ-- 813
Query: 185 AFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQ 240
G++ A + K PK KKKK R KE+EE T ++ +K P +E+
Sbjct: 814 -------GEEDDAEGQDQDKKSPKPKKKKHR-KEKEERTKGKKK--SKKQPPGSEE 859
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 48.9 bits (115), Expect = 7e-06
Identities = 33/168 (19%), Positives = 71/168 (42%), Gaps = 20/168 (11%)
Query: 201 QSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDE 260
+ + + +K++ ++RQ+E E +ER ++ E Q R+ K + R ++ +
Sbjct: 52 REKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRN 111
Query: 261 REGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEA 320
RE KG + D R++ + R+ +++++ + E+ E + KE
Sbjct: 112 RERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKE- 170
Query: 321 AGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQG 368
R+K+R+++ +E E R E+ R W +G
Sbjct: 171 -------------------RKKERKKERKEKKKEEKRREDKKRKWGEG 199
Score = 43.9 bits (102), Expect = 2e-04
Identities = 32/164 (19%), Positives = 69/164 (42%), Gaps = 9/164 (5%)
Query: 209 KKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGN 268
K+ ++ R ++ E +ER + + H E++ + ++K+R Q K D + +
Sbjct: 15 KETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQ--KERDRQRQRERET 72
Query: 269 EKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEE 328
E+E + + QT++ K + ++R + +GG+ ++ +TE
Sbjct: 73 ERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDK----QTER 128
Query: 329 VESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSREQ 372
R R ++RQ+Q E + E RW + R++
Sbjct: 129 ERDRERERQRQRERERQRQRERK---RETDRERQRWAEREERKK 169
Score = 37.0 bits (84), Expect = 0.029
Identities = 21/122 (17%), Positives = 53/122 (43%)
Query: 180 EAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAE 239
E + Q R + + + + + + ++K++ R +E ER+ E+ +
Sbjct: 75 ETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRER 134
Query: 240 QNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKK 299
+ R+ +++++R +E K +RE +E + +E+ + R+ KK+
Sbjct: 135 ERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKR 194
Query: 300 RW 301
+W
Sbjct: 195 KW 196
Score = 32.0 bits (71), Expect = 0.93
Identities = 16/79 (20%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Query: 201 QSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDE 260
Q+E + ++++++R+++ E + + + D + AE R+ +KK+R+ + K E
Sbjct: 125 QTERERDRERERQRQRERERQRQRERKRETDRERQRWAE---REERKKERKKERKKERKE 181
Query: 261 REGTTKGNEKEDAAGTSGL 279
++ K E + G+
Sbjct: 182 KKKEEKRREDKKRKWGEGI 200
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 48.9 bits (115), Expect = 7e-06
Identities = 47/210 (22%), Positives = 94/210 (44%), Gaps = 20/210 (9%)
Query: 136 DDDNQGSKSPKILTDEMLLQACEGRTAHKAARLGITMKAKLARLEAQE------QAFLAR 189
D+ + +K ++ ++ +A + AR +A+ R QE Q L +
Sbjct: 607 DEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQK 666
Query: 190 LKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKK 249
K ++ + +E+K + +++ +++ E+E ER + + + E EQ + +++++
Sbjct: 667 KKEEEQERLRKAAEAK--RLAEQREQERREQERREQERREQERREQERREQERQLAEQER 724
Query: 250 RRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMG 309
RR QE ++ ERE E+E A +EQ + L + KKK+ E+
Sbjct: 725 RREQE-RLQAERE----LQEREKALRL-------QKEQLQRELEEKKKKEEQQRLAERQL 772
Query: 310 VLEEGGKGKEAAGSVRTEEVESRAYADPCS 339
E+ K KEAAG+ + V + C+
Sbjct: 773 QEEQEKKAKEAAGASKALNVTVDVQSPACT 802
Score = 41.6 bits (96), Expect = 0.001
Identities = 38/170 (22%), Positives = 76/170 (44%), Gaps = 12/170 (7%)
Query: 194 DPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQ 253
D + + E +K KKK K+ EE A + + + + +Q ++++RRHQ
Sbjct: 607 DEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQ-----EEEERRHQ 661
Query: 254 E---GKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGV 310
E K +E+E K E + A E +E+ Q R+ +++++ E+E+
Sbjct: 662 ELLQKKKEEEQERLRKAAEAKRLA-EQREQERREQERREQERREQERREQERREQERQLA 720
Query: 311 LEEGGKGKE---AAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDR 357
+E + +E A ++ E R + R + ++++EE L +R
Sbjct: 721 EQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAER 770
Score = 41.2 bits (95), Expect = 0.002
Identities = 48/210 (22%), Positives = 92/210 (43%), Gaps = 21/210 (10%)
Query: 170 ITMKAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERND 229
+ M K + +E + Q L L+ ++ A QL+ + K ++ KRR+ EE + ER
Sbjct: 526 LRMDPKCSFVEKERQR-LENLRRKEE-AEQLRRQ----KVEEDKRRRLEEVKLKREERL- 578
Query: 230 ADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEK---EDAAGTSGLGELNSRE 286
+ A + + + K++K++ E K + E T K E+ E+ A +
Sbjct: 579 ---RKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEV 635
Query: 287 QTNQSLRKGKKKKRW-HHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQ 345
+ + + ++ RW EEE+ E K KE + E++ A+ + ++ Q
Sbjct: 636 EARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQ 695
Query: 346 QQEEEDLNLEDRGEETFRWWNQGSREQSMQ 375
++ E++ ++R E Q REQ Q
Sbjct: 696 ERREQERREQERRE-------QERREQERQ 718
Score = 40.4 bits (93), Expect = 0.003
Identities = 41/175 (23%), Positives = 81/175 (46%), Gaps = 15/175 (8%)
Query: 189 RLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKK 248
+LK ++ LQ+ + + K++K++Q E++ A DEK + E+ + + K K
Sbjct: 571 KLKREERLRKVLQARERVEQMKEEKKKQIEQKFA------QIDEKTEKAKEERLAEEKAK 624
Query: 249 KRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKM 308
K+ K +E E K ++E+A L + E+ +Q L + KK++ E+E++
Sbjct: 625 KKA--AAKKMEEVEARRK--QEEEARRLRWLQQ-EEEERRHQELLQKKKEE----EQERL 675
Query: 309 GVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFR 363
E + E R E+ RR++ ++++E L ++R E R
Sbjct: 676 RKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQER 730
Score = 39.3 bits (90), Expect = 0.006
Identities = 51/265 (19%), Positives = 109/265 (41%), Gaps = 15/265 (5%)
Query: 95 LSKETTRYNHPKPNLLYQKFVKMATLTSGGEKPNKDLESCSDDDNQGSKSPKILTDEMLL 154
+ + T PK + + ++ ++ L E + +D + + K+ +E L
Sbjct: 520 IKRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLR 579
Query: 155 QACEGRTAHKAARLGITMKAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKR 214
+ + R + ++ K ++ + AQ + K + + + ++ K ++ +
Sbjct: 580 KVLQAR--ERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEA 637
Query: 215 RQKEEEEATASERNDADEKHPEHAEQNIRKSKKKK------RRHQEGK-VSDEREGTTKG 267
R+K+EEEA +E+ H E KKK+ R+ E K ++++RE +
Sbjct: 638 RRKQEEEARRLRWLQQEEEERRHQEL---LQKKKEEEQERLRKAAEAKRLAEQREQERRE 694
Query: 268 NE-KEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRT 326
E +E E REQ Q + +++++ + E+ L+E K
Sbjct: 695 QERREQERREQERREQERREQERQLAEQERRREQERLQAER--ELQEREKALRLQKEQLQ 752
Query: 327 EEVESRAYADPCSRRKKRQQQEEED 351
E+E + + R +RQ QEE++
Sbjct: 753 RELEEKKKKEEQQRLAERQLQEEQE 777
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 48.9 bits (115), Expect = 7e-06
Identities = 47/210 (22%), Positives = 94/210 (44%), Gaps = 20/210 (9%)
Query: 136 DDDNQGSKSPKILTDEMLLQACEGRTAHKAARLGITMKAKLARLEAQE------QAFLAR 189
D+ + +K ++ ++ +A + AR +A+ R QE Q L +
Sbjct: 603 DEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQK 662
Query: 190 LKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKK 249
K ++ + +E+K + +++ +++ E+E ER + + + E EQ + +++++
Sbjct: 663 KKEEEQERLRKAAEAK--RLAEQREQERREQERREQERREQERREQERREQERQLAEQER 720
Query: 250 RRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMG 309
RR QE ++ ERE E+E A +EQ + L + KKK+ E+
Sbjct: 721 RREQE-RLQAERE----LQEREKALRL-------QKEQLQRELEEKKKKEEQQRLAERQL 768
Query: 310 VLEEGGKGKEAAGSVRTEEVESRAYADPCS 339
E+ K KEAAG+ + V + C+
Sbjct: 769 QEEQEKKAKEAAGASKALNVTVDVQSPACT 798
Score = 42.4 bits (98), Expect = 7e-04
Identities = 42/225 (18%), Positives = 100/225 (44%), Gaps = 9/225 (4%)
Query: 132 ESCSDDDNQGSKSPKILTDEMLLQACEGRTAHKAARLGITMKAKLARLEAQEQAFLARLK 191
+ +D + + K+ +E L + + R + ++ K ++ + AQ + K
Sbjct: 553 QKVEEDKRRRLEEVKLKREERLRKVLQAR--ERVEQMKEEKKKQIEQKFAQIDEKTEKAK 610
Query: 192 GQDPGAPQLQSESKPPKKKKKKRRQKEEEEATA---SERNDADEKHPEHAEQNIRKSKKK 248
+ + + ++ K ++ + R+K+EEEA ++ + + +H E ++ + +++
Sbjct: 611 EERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQER 670
Query: 249 KRRHQEGK-VSDEREGTTKGNE-KEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEE 306
R+ E K ++++RE + E +E E REQ Q + +++++ + E
Sbjct: 671 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 730
Query: 307 KMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEED 351
+ L+E K E+E + + R +RQ QEE++
Sbjct: 731 R--ELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQE 773
Score = 41.6 bits (96), Expect = 0.001
Identities = 43/192 (22%), Positives = 82/192 (42%), Gaps = 30/192 (15%)
Query: 207 PKKKKKKR----RQKEEEEATASERNDADE---------KHPEH------AEQNIRKSKK 247
PK+K+++R R+KEE E ++ + D+ K E A + + + K+
Sbjct: 530 PKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKE 589
Query: 248 KKRRHQEGKVSDEREGTTKGNEK---EDAAGTSGLGELNSREQTNQSLRKGKKKKRW-HH 303
+K++ E K + E T K E+ E+ A + + + + ++ RW
Sbjct: 590 EKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQ 649
Query: 304 EEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFR 363
EEE+ E K KE + E++ A+ + ++ Q++ E++ ++R E
Sbjct: 650 EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERRE---- 705
Query: 364 WWNQGSREQSMQ 375
Q REQ Q
Sbjct: 706 ---QERREQERQ 714
Score = 41.6 bits (96), Expect = 0.001
Identities = 38/170 (22%), Positives = 76/170 (44%), Gaps = 12/170 (7%)
Query: 194 DPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQ 253
D + + E +K KKK K+ EE A + + + + +Q ++++RRHQ
Sbjct: 603 DEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQ-----EEEERRHQ 657
Query: 254 E---GKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGV 310
E K +E+E K E + A E +E+ Q R+ +++++ E+E+
Sbjct: 658 ELLQKKKEEEQERLRKAAEAKRLA-EQREQERREQERREQERREQERREQERREQERQLA 716
Query: 311 LEEGGKGKE---AAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDR 357
+E + +E A ++ E R + R + ++++EE L +R
Sbjct: 717 EQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAER 766
Score = 40.4 bits (93), Expect = 0.003
Identities = 41/175 (23%), Positives = 81/175 (46%), Gaps = 15/175 (8%)
Query: 189 RLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKK 248
+LK ++ LQ+ + + K++K++Q E++ A DEK + E+ + + K K
Sbjct: 567 KLKREERLRKVLQARERVEQMKEEKKKQIEQKFA------QIDEKTEKAKEERLAEEKAK 620
Query: 249 KRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKM 308
K+ K +E E K ++E+A L + E+ +Q L + KK++ E+E++
Sbjct: 621 KKA--AAKKMEEVEARRK--QEEEARRLRWLQQ-EEEERRHQELLQKKKEE----EQERL 671
Query: 309 GVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFR 363
E + E R E+ RR++ ++++E L ++R E R
Sbjct: 672 RKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQER 726
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 48.5 bits (114), Expect = 1e-05
Identities = 40/185 (21%), Positives = 91/185 (49%), Gaps = 11/185 (5%)
Query: 199 QLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVS 258
Q+Q + + +++++ R++EE+ E+ E+ + E+ +RK ++++ R QE ++
Sbjct: 214 QMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRK-QEEQMREQEEQMR 272
Query: 259 DEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGK 318
++ E K E+ + +G E REQ Q +R+ +++ R EE+ E+ GK +
Sbjct: 273 EQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQ-MREQEEQMR-EQEEQMREQEEQMGKQE 330
Query: 319 EAAGSVRTEEVESR----AYADPCSRRKKRQQQEEEDLNLED----RGEETFRWWNQGSR 370
E + + E + + ++++ Q++EE + ++ + EE R + R
Sbjct: 331 EQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMR 390
Query: 371 EQSMQ 375
+Q Q
Sbjct: 391 KQEEQ 395
Score = 47.4 bits (111), Expect = 2e-05
Identities = 40/179 (22%), Positives = 92/179 (51%), Gaps = 20/179 (11%)
Query: 199 QLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVS 258
Q++ + + ++++++ R++EE+ E+ + +E+ E EQ + ++++ R QE ++
Sbjct: 256 QMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQ--MREQEEQMREQEEQMR 313
Query: 259 DEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGK 318
++ E + E+E+ G +EQ + +K++ W +EE+MG EE + +
Sbjct: 314 EQEE---QMREQEEQMGKQEEQMWEQKEQMWE-----QKEQMW-KQEEQMGEQEEQMQKQ 364
Query: 319 EAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDL--NLEDRGEETFRWWNQGSREQSMQ 375
E VR +E + R + +++++ +++EE + E GE+ + REQ Q
Sbjct: 365 EE--QVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQ-----KEQMREQEEQ 416
Score = 47.0 bits (110), Expect = 3e-05
Identities = 38/199 (19%), Positives = 93/199 (46%), Gaps = 30/199 (15%)
Query: 182 QEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDAD-EKHPEHAEQ 240
+++ + +GQ + E + +K++++ ++EE+ E + E+ + E+
Sbjct: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEE 248
Query: 241 NIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKR 300
++K +++ R+ +E RE + E+E+ L +EQT Q + G+++++
Sbjct: 249 QVQKQEEQMRKQEE----QMREQEEQMREQEEQM-------LKQKEQTEQEEQTGEQEEQ 297
Query: 301 WHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEE 360
+EE+M EE +R +E + R + +++++ +++E + E+
Sbjct: 298 MREQEEQMREQEE---------QMREQEEQMREQEEQMGKQEEQMWEQKEQM-----WEQ 343
Query: 361 TFRWWNQ----GSREQSMQ 375
+ W Q G +E+ MQ
Sbjct: 344 KEQMWKQEEQMGEQEEQMQ 362
Score = 44.3 bits (103), Expect = 2e-04
Identities = 35/167 (20%), Positives = 80/167 (47%), Gaps = 6/167 (3%)
Query: 210 KKKKRRQKEEEEATASERNDADEKHPEHAEQNIR-KSKKKKRRHQEGKVSDEREGTTKGN 268
++++ + +E+E + E+ + EQ + + ++ + R QEG+V E+EG +
Sbjct: 125 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR-EQEGQVREQ 183
Query: 269 EKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEE 328
E + +GE + Q + G+++++ +EE+MG EE + +E + E+
Sbjct: 184 EGQVREQEGQMGEQEG-QMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQ 242
Query: 329 V---ESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSREQ 372
V E + RK+ +Q E++ + ++ E+ + Q +E+
Sbjct: 243 VQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEE 289
Score = 38.1 bits (87), Expect = 0.013
Identities = 29/164 (17%), Positives = 72/164 (43%), Gaps = 3/164 (1%)
Query: 150 DEMLLQACEGRTAHKAARLGITMKAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKK 209
++ML Q + + M+ + ++ QE+ + + Q+ + + +
Sbjct: 276 EQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWE 335
Query: 210 KKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNE 269
+K++ +++E+ E+ E+ + E+ +RK +++ R+ +E E + + +
Sbjct: 336 QKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQ 395
Query: 270 KEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEE 313
+ G + REQ Q G++K++ +EE MG +E
Sbjct: 396 MGEQKEQMGEQKEQMREQEEQ---MGEQKEQMRKQEEHMGEQKE 436
Score = 34.3 bits (77), Expect = 0.19
Identities = 34/169 (20%), Positives = 77/169 (45%), Gaps = 20/169 (11%)
Query: 210 KKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNE 269
++++ + +E+E + E+ + EQ + + QE ++ ++ E K E
Sbjct: 167 REQEGQVREQEGQVREQEGQVREQEGQMGEQ------EGQMGEQEEQMGEQEEQMQKQEE 220
Query: 270 KEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEV 329
+ +GE + Q + G+++++ +EE++ EE + +E +R +E
Sbjct: 221 Q--------MGE-QEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEE--QMREQEE 269
Query: 330 ESRAYADPCSRRKKRQQQEEEDLNLEDR---GEETFRWWNQGSREQSMQ 375
+ R + ++K++ +QEE+ E++ EE R + REQ Q
Sbjct: 270 QMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQ 318
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 47.8 bits (112), Expect = 2e-05
Identities = 34/174 (19%), Positives = 80/174 (45%), Gaps = 7/174 (4%)
Query: 189 RLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKK 248
R + D + +S K +++++ R++E E ER E+ E + R+ KK
Sbjct: 371 RERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKK 430
Query: 249 KRRHQEGKVSDEREGTTKGNEKEDAAGTSGL--GELNSREQTNQSLRKGKKKKRWHHEEE 306
+ R ++ + + ER + +++AA L E+ R++T + ++ +++ EE
Sbjct: 431 RDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAERE-----EER 485
Query: 307 KMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEE 360
+ + +E + KE + + + Y +++ R +++E + + DR E
Sbjct: 486 RREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKRE 539
Score = 43.1 bits (100), Expect = 4e-04
Identities = 32/155 (20%), Positives = 62/155 (40%), Gaps = 3/155 (1%)
Query: 203 ESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDERE 262
E K K+K+++ +KE E + + + E + R+ +K+K R +E + +R+
Sbjct: 293 EEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRD 352
Query: 263 GTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAG 322
T + + D S ++ R +K + E E+ E + +E
Sbjct: 353 RTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERE---RERERERERER 409
Query: 323 SVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDR 357
E R + KKR ++E+E+ E R
Sbjct: 410 EREREREREREREREREKDKKRDREEDEEDAYERR 444
Score = 39.3 bits (90), Expect = 0.006
Identities = 30/157 (19%), Positives = 67/157 (42%), Gaps = 7/157 (4%)
Query: 201 QSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDE 260
+ E + ++++++ R++E E E+ E+ E R ++ + R +E +
Sbjct: 311 ERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRD 370
Query: 261 REGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEA 320
RE ++ N+ + RE+ + R+ ++++ E E+ E + +E
Sbjct: 371 RERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERE---REREREREK 427
Query: 321 AGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDR 357
EE E AY RRK ++ E++ ++R
Sbjct: 428 DKKRDREEDEEDAY----ERRKLERKLREKEAAYQER 460
Score = 38.5 bits (88), Expect = 0.010
Identities = 34/179 (18%), Positives = 68/179 (37%), Gaps = 9/179 (5%)
Query: 173 KAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADE 232
K K E + R K +D + + + ++ + + + + +R E
Sbjct: 337 KEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERE 396
Query: 233 KHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSL 292
+ E + R+ ++++ R +E + ERE K + +ED +L
Sbjct: 397 REREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLE--------- 447
Query: 293 RKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEED 351
RK ++K+ + E K + E K +E EE R A R K+ + ++D
Sbjct: 448 RKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDD 506
Score = 36.6 bits (83), Expect = 0.038
Identities = 43/205 (20%), Positives = 74/205 (36%), Gaps = 32/205 (15%)
Query: 187 LARLKGQDPGAPQLQSESKPPKKKKKKRRQ-----------------KEEEEATASERND 229
L R + AP +S+S P KKKK+K+ KE+ A E +
Sbjct: 214 LIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDK 273
Query: 230 AD----------EKHPEHAEQNIRKSKK-----KKRRHQEGKVSDEREGTTKGNEKEDAA 274
D + H + E+ +K K+ K+RR +E + ERE + E+E
Sbjct: 274 RDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERERERER 333
Query: 275 GTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAY 334
E + ++ + K++ R E E + S E+ R
Sbjct: 334 EREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRER 393
Query: 335 ADPCSRRKKRQQQEEEDLNLEDRGE 359
R ++R+++ E + E E
Sbjct: 394 ERERERERERERERERERERERERE 418
Score = 36.2 bits (82), Expect = 0.049
Identities = 39/182 (21%), Positives = 75/182 (41%), Gaps = 17/182 (9%)
Query: 208 KKKKKKRRQKEEEEATASERNDAD----EKHPEHAEQ----NIRKSKKKKRRHQEGKVSD 259
+++K K+R +EE+E A ER + EK + E+ IR+ KK + +E + +
Sbjct: 424 EREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREE 483
Query: 260 EREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKE 319
ER + KE L + + + R +KR E++M E K ++
Sbjct: 484 ERR---REMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREK 540
Query: 320 AAGSVRTEEVESRAYADPCSRRKKRQQQEEE------DLNLEDRGEETFRWWNQGSREQS 373
+ + + + DP + ++ +Q+ E E EE + + RE+
Sbjct: 541 EELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEP 600
Query: 374 MQ 375
M+
Sbjct: 601 ME 602
Score = 35.8 bits (81), Expect = 0.064
Identities = 36/169 (21%), Positives = 69/169 (40%), Gaps = 23/169 (13%)
Query: 208 KKKKKKRRQKEEEEATASERNDAD-----------EKHPEHAEQNIRKSKKKKRRHQEGK 256
++++++R +++E+E D D ++ + R S + K R + +
Sbjct: 327 REREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSRE 386
Query: 257 VSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGV-----L 311
S +RE + + + RE+ + R+ +K K+ EE++ L
Sbjct: 387 KSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKL 446
Query: 312 EEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEE 360
E + KEAA R + E R RKK ++ E+E E+R E
Sbjct: 447 ERKLREKEAAYQERLKNWEIR-------ERKKTREYEKEAEREEERRRE 488
Score = 29.6 bits (65), Expect = 4.6
Identities = 19/75 (25%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 173 KAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADE 232
K + LE Q LA DP A + E + ++++ + +Q+ E E E+ + +E
Sbjct: 537 KREKEELEEIRQRLLAE-GHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEE 595
Query: 233 KHPEHAEQNIRKSKK 247
K E E+ +K
Sbjct: 596 KREEPMEEEEEPEQK 610
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 47.8 bits (112), Expect = 2e-05
Identities = 43/210 (20%), Positives = 99/210 (47%), Gaps = 24/210 (11%)
Query: 172 MKAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDAD 231
++ + ++ QE+ + K +L+ + K +++K+ R Q+E+ + + + +
Sbjct: 302 LREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQE 361
Query: 232 EKHPEHAEQNIRKSKK-----KKRRHQEGKVSDEREGTTKGN----EKEDAAGTSGLGEL 282
EK E E+ R+ ++ K+ R QE K+ D+ E + + EKE+ +
Sbjct: 362 EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE--------RM 413
Query: 283 NSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRK 342
+E+ + + K +++K+ +E+K EE + +E +R E + R + ++
Sbjct: 414 REQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEE---RIREREKKMREEEETMREQE 470
Query: 343 KRQQQEEEDLNLEDRGEETFRWWNQGSREQ 372
++ Q++EE++ ++ E W Q EQ
Sbjct: 471 EKMQKQEENMWEQEEKE----WQQQRLPEQ 496
Score = 43.1 bits (100), Expect = 4e-04
Identities = 42/204 (20%), Positives = 91/204 (44%), Gaps = 15/204 (7%)
Query: 172 MKAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKK-KKKRRQKEEEEATASERNDA 230
M+ + ++ QE+ R+ QD + + + +K ++ + +EE++ E+
Sbjct: 385 MREQEQKMRDQEE----RMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTR 440
Query: 231 DEKHPEHAEQNIRKSKKKKR------RHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNS 284
D++ E+ IR+ +KK R R QE K+ + E + EKE L E
Sbjct: 441 DQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQ--QRLPEQKE 498
Query: 285 REQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKR 344
+ + +++ +++K W EE+ E G+ K+ + E E + + R +
Sbjct: 499 KLWEQEKMQE-QEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 557
Query: 345 QQQEEEDLNLEDR-GEETFRWWNQ 367
Q+ +++ +E + E+ + W+Q
Sbjct: 558 QKMWDQEERMEKKTQEQEKKTWDQ 581
Score = 42.7 bits (99), Expect = 5e-04
Identities = 46/183 (25%), Positives = 88/183 (48%), Gaps = 22/183 (12%)
Query: 189 RLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKK 248
RL+ ++ + + + +K +++++ +E+E+ T D +EK E E+ IR+ +KK
Sbjct: 405 RLREKEERMREQEKMWEQVEKMREEKKMQEQEKKT----RDQEEKMQE--EERIREREKK 458
Query: 249 KRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKM 308
R E E T + E++ + E +E Q L + +K+K W E+EKM
Sbjct: 459 MR---------EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPE-QKEKLW--EQEKM 506
Query: 309 GVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDR-GEETFRWWNQ 367
EE K E +R +E E R++K ++QE++ E++ ++ + W+Q
Sbjct: 507 QEQEE--KIWEQEEKIRDQE-EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 563
Query: 368 GSR 370
R
Sbjct: 564 EER 566
Score = 39.7 bits (91), Expect = 0.004
Identities = 40/197 (20%), Positives = 88/197 (44%), Gaps = 22/197 (11%)
Query: 189 RLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKK 248
+++ Q+ + + + + ++K + ++ E++ E+ D++ E+ +R+ +KK
Sbjct: 538 KMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKK 597
Query: 249 KR------RHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWH 302
R R QE K+ ++ E + EK + E + Q + +++K W
Sbjct: 598 MREEEEMMREQEEKMQEQEEKMQEQEEK--------MWEQEEKMQEQEEKMWEQEEKMWE 649
Query: 303 HEE---EKMGVLEEGGK---GKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLED 356
EE E+ + E+ K ++ + +E E + + KK Q+QE++ + E
Sbjct: 650 QEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQE-KMEKKTQEQEKKTWDQEK 708
Query: 357 -RGEETFRWWNQGSREQ 372
R EE+ R + RE+
Sbjct: 709 MREEESMREREKKMREE 725
Score = 39.7 bits (91), Expect = 0.004
Identities = 35/162 (21%), Positives = 76/162 (46%), Gaps = 9/162 (5%)
Query: 199 QLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVS 258
++ E + ++++++ Q++EEE E +++ +Q + + K+K H++
Sbjct: 727 EMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEK---M 783
Query: 259 DEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGK 318
E+E + EK G+ + +R G+++K W +EEKM EE G+
Sbjct: 784 QEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMR-GQEEKMWG-QEEKMWGQEEKMWGQ 841
Query: 319 EAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEE 360
E + E++E + + +K ++QEE+ E++ E
Sbjct: 842 EEKMWGQEEKMEEKMQ----GQEEKMREQEEKMRGQEEKMRE 879
Score = 38.9 bits (89), Expect = 0.008
Identities = 44/205 (21%), Positives = 92/205 (44%), Gaps = 22/205 (10%)
Query: 172 MKAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDAD 231
M+ + ++ QE+ + + Q+ + + + ++ +++ ++ EEE E+ +
Sbjct: 553 MRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ---E 609
Query: 232 EKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQS 291
EK E E+ + +++K QE K+ ++ E + EK + E + Q
Sbjct: 610 EKMQEQEEK--MQEQEEKMWEQEEKMQEQEEKMWEQEEK--------MWEQEEKMWEQQR 659
Query: 292 LRKGKKKKRWHH----EEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQ 347
L + +K+K W H E+EKM EE +E +T+E E + + R ++ ++
Sbjct: 660 LPE-QKEKLWEHEKMQEQEKMQEQEEKIWEQEKM-EKKTQEQEKKTWDQEKMREEESMRE 717
Query: 348 EEEDLNLEDRGEETFRWWNQGSREQ 372
E+ + E EE R + +EQ
Sbjct: 718 REKKMREE---EEMMREQEEKMQEQ 739
Score = 38.1 bits (87), Expect = 0.013
Identities = 38/178 (21%), Positives = 78/178 (43%), Gaps = 36/178 (20%)
Query: 203 ESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDERE 262
E + ++++KK R++EE + + +++K + QE K+ ++ E
Sbjct: 711 EEESMREREKKMREEEE----------------------MMREQEEKMQEQEEKMQEQEE 748
Query: 263 GTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHE--EEKMGVLEEGGKGKEA 320
+ EK + E + Q L + +K+K W HE +E+ + E+ K ++
Sbjct: 749 EMWEQEEK--------MWEQEEKMWEQQRLPE-QKEKLWEHEKMQEQEKIWEQEEKMRDQ 799
Query: 321 AGSVRTEEVESRAYADPC-SRRKKRQQQEEEDLNLEDR--GEETFRWWNQGSREQSMQ 375
+R +E + R + + +K QEE+ E++ G+E W + E+ MQ
Sbjct: 800 EEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQ 857
Score = 37.7 bits (86), Expect = 0.017
Identities = 39/171 (22%), Positives = 82/171 (47%), Gaps = 16/171 (9%)
Query: 208 KKKKKKRRQKEEEEATASER-NDADEKHPEHAEQNIRKSKK-----KKRRHQEGKVSDER 261
++++KK R++EE+ ER + + K E E+ R+ K+ K+ R QE ++ +++
Sbjct: 282 REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQK 341
Query: 262 EGTTKGNEKEDAAGTSGLGELNSREQT----NQSLRKGKKKKRWHHEEEKM-----GVLE 312
E + + ++ E REQ Q R +++K+ +E+KM + E
Sbjct: 342 ELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWE 401
Query: 313 EGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFR 363
+ + +E +R +E + + KK Q+QE++ + E++ +E R
Sbjct: 402 QDERLREKEERMREQE-KMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEER 451
Score = 37.4 bits (85), Expect = 0.022
Identities = 38/182 (20%), Positives = 82/182 (45%), Gaps = 14/182 (7%)
Query: 199 QLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRR--HQEGK 256
++ + K +++K R Q+++ + D ++K + E+ +K+++++++ QE K
Sbjct: 525 EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEK 584
Query: 257 VSDE---REGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEE 313
+ +E RE K E+E+ + E + Q + + +++K W +EEKM EE
Sbjct: 585 MREEERMREREKKMREEEEM-----MREQEEKMQEQEEKMQEQEEKMW-EQEEKMQEQEE 638
Query: 314 GGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSREQS 373
+E E+ E +K++ + E+ E E+ + W Q E+
Sbjct: 639 KMWEQE---EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKK 695
Query: 374 MQ 375
Q
Sbjct: 696 TQ 697
Score = 34.7 bits (78), Expect = 0.14
Identities = 39/177 (22%), Positives = 80/177 (45%), Gaps = 28/177 (15%)
Query: 199 QLQSESKPPKKKKKKRRQKEEEEATASERN-DADEKHPEHAE-----QNIRKSKKKKRRH 252
++Q + + +++++K ++EE+ E+ + +EK E E Q + + K+K H
Sbjct: 611 KMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEH 670
Query: 253 QEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLE 312
++ E+E + EK + E E+ Q ++KK W ++EKM
Sbjct: 671 EK---MQEQEKMQEQEEK--------IWEQEKMEKKTQE----QEKKTW--DQEKM---R 710
Query: 313 EGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDL--NLEDRGEETFRWWNQ 367
E +E +R EE R + ++++ Q++EE++ E E+ + W Q
Sbjct: 711 EEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQ 767
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 47.4 bits (111), Expect = 2e-05
Identities = 46/201 (22%), Positives = 94/201 (46%), Gaps = 16/201 (7%)
Query: 182 QEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQN 241
+E+ + K Q+ A + E K ++++K R Q+E + + + +EK E E+
Sbjct: 368 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEE- 426
Query: 242 IRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGK---KK 298
+ +++K R QE K+ RE K E+E+ E+ ++ ++GK ++
Sbjct: 427 -MQEQEEKMRRQEEKI---REQEKKIREQEEKIREQ--EEMMQEQEEKMGEQEGKMCEQE 480
Query: 299 KRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLED-- 356
+ +EEKM EE K +E +R +E + R + ++++ ++EE + ++
Sbjct: 481 AKMQEQEEKMRRQEE--KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 538
Query: 357 --RGEETFRWWNQGSREQSMQ 375
EE R + REQ ++
Sbjct: 539 MQEQEEKMRRQEEKMREQEVR 559
Score = 43.5 bits (101), Expect = 3e-04
Identities = 41/177 (23%), Positives = 77/177 (43%), Gaps = 25/177 (14%)
Query: 208 KKKKKKRRQ------KEEEEATASERNDADEKHPEHAEQNIRKSK---KKKRRHQEGKVS 258
+K++K RRQ KEE+ E+ EK E E+ + K ++KR+ QE K+
Sbjct: 327 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 386
Query: 259 DEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGK 318
+ E + EK + E Q + +++K W EEE + E+ K +
Sbjct: 387 RQEEKIREQEEK--------IREQEEMMQEQEEKMGEQEEKMWEQEEE---MQEQEEKMR 435
Query: 319 EAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSREQSMQ 375
+R +E + R + +++ Q++EE + GE+ + Q ++ Q +
Sbjct: 436 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM-----GEQEGKMCEQEAKMQEQE 487
Score = 43.5 bits (101), Expect = 3e-04
Identities = 41/192 (21%), Positives = 87/192 (45%), Gaps = 21/192 (10%)
Query: 203 ESKPPKKKKKKRRQKEEEEATASERNDADEKHPE--HAEQNIRKSKKKKR------RHQE 254
E ++K +++ +K +EE E+ E+ + E+ IR+ ++K R + QE
Sbjct: 351 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQE 410
Query: 255 GKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHE-----EEKMG 309
K+ ++ E + E+ + + + +R+ ++K R E EEKMG
Sbjct: 411 EKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMG 470
Query: 310 VLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDR--GEETFRWWNQ 367
E+ GK E ++ +E + R + ++K+ +++EE + ++ E+ + W Q
Sbjct: 471 --EQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ 528
Query: 368 GSR----EQSMQ 375
+ E+ MQ
Sbjct: 529 EEKMCEQEEKMQ 540
Score = 38.5 bits (88), Expect = 0.010
Identities = 42/176 (23%), Positives = 81/176 (46%), Gaps = 29/176 (16%)
Query: 180 EAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQ----KEEEEATASERNDADEKHP 235
E +E+ + + Q+ + E K +++KK R Q +E+EE + E+
Sbjct: 415 EQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEG 474
Query: 236 EHAEQNIR-KSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRK 294
+ EQ + + +++K R QE K+ RE K E+E+ REQ + + +
Sbjct: 475 KMCEQEAKMQEQEEKMRRQEEKI---REQEKKIREQEE----------KIREQ--EEMMQ 519
Query: 295 GKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEE 350
+++K W EE+ + E+ K +E +R +E + R + + +QQEE+
Sbjct: 520 EQEEKMWEQEEK---MCEQEEKMQEQEEKMRRQEEKMR------EQEVRLRQQEEK 566
>gi|118600973 RNA binding motif protein, X-linked 2 [Homo sapiens]
Length = 322
Score = 47.4 bits (111), Expect = 2e-05
Identities = 42/173 (24%), Positives = 71/173 (41%), Gaps = 11/173 (6%)
Query: 193 QDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRH 252
+D + + K KKKKKK ++K + E A + + + + E++ KK ++
Sbjct: 150 EDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKN 209
Query: 253 QE-GKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVL 311
E + S+ REG + K A + G +L + + + K R EEK +
Sbjct: 210 SERAQKSEPREG--QKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRI- 266
Query: 312 EEGGKGKEAAGSVRTEEVESRAYADPCSRRKK-------RQQQEEEDLNLEDR 357
+ G+ +A S E R+Y R K R+ +E E N DR
Sbjct: 267 RDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRARRSRERESSNPSDR 319
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 46.6 bits (109), Expect = 4e-05
Identities = 38/177 (21%), Positives = 85/177 (48%), Gaps = 23/177 (12%)
Query: 201 QSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRR-----HQEG 255
Q E + ++K +++ +++E+EA + E+ E+ IR+ +KK R H++
Sbjct: 409 QEEKRQEEEKIREQEKRQEQEAKMWRQ----EEKIREQEEKIREQEKKMWRQEEKIHEQE 464
Query: 256 KVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGG 315
K+ +E K E+E+ E+ ++ ++K++ H +EEK+ EE
Sbjct: 465 KIREEE----KRQEQEEM--------WRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEE-- 510
Query: 316 KGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETFRWWNQGSREQ 372
K +R +E + R + R++++ +++EE E++ E + W + R++
Sbjct: 511 KVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQE 567
Score = 45.4 bits (106), Expect = 8e-05
Identities = 47/203 (23%), Positives = 89/203 (43%), Gaps = 36/203 (17%)
Query: 191 KGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKK-- 248
K Q+ + E K ++++K RQ+E+ +R + +EK + E+ IR+ ++K
Sbjct: 564 KRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ-EEKIREQEEKIQ 622
Query: 249 ----KRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHE 304
K R QE K+ ++ E T + EK +GE + + + +++ W E
Sbjct: 623 EQEEKIREQEEKIREQEEMTQEQEEK--------MGEQEEKMCEQEEKMQEQEETMWRQE 674
Query: 305 EEKMGVLEEGGKGKEAAGSVRTEEVESRAYADP--------CSRRKKRQQQEEEDLNLED 356
E+ + E+ K +E +R +E + + C + +K Q+QEE+ E+
Sbjct: 675 EK---IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 731
Query: 357 RGEETFRWWNQGSR----EQSMQ 375
+ W Q R E+ MQ
Sbjct: 732 ------KMWEQEVRLRQQEEKMQ 748
Score = 39.3 bits (90), Expect = 0.006
Identities = 54/249 (21%), Positives = 104/249 (41%), Gaps = 36/249 (14%)
Query: 146 KILTDEMLLQACEGRTAHKAARLGITMKAKLARLEAQ---------------EQAFLARL 190
K+L + LQA +A LG +++ A+L+AQ E+ +
Sbjct: 255 KLLLPQQQLQA-------EADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEE 307
Query: 191 KGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKR 250
K Q+ + E K ++++K R Q+E+ + +EK E K +K +R
Sbjct: 308 KIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR 367
Query: 251 RHQ-----EGKVSDEREGTTKGNEK--EDAAGTSGLGELNSREQTNQSLRKGKKKKRWHH 303
+ + E K+ + E + EK E ++ +E+ Q K +++++
Sbjct: 368 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 427
Query: 304 EEEKMGVLEEGGKGKEAAGSVRTEE-----VESRAYADPCSRRKKRQQQEEEDLNLEDRG 358
+E KM EE K +E +R +E E + + R ++++Q++EE E++
Sbjct: 428 QEAKMWRQEE--KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 485
Query: 359 EETFRWWNQ 367
E W Q
Sbjct: 486 HEQEEIWRQ 494
Score = 38.9 bits (89), Expect = 0.008
Identities = 35/148 (23%), Positives = 74/148 (50%), Gaps = 8/148 (5%)
Query: 210 KKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNE 269
+++KR+++E++ E+ E+ E+ IR+ +++KR+ QE K+ + E + E
Sbjct: 561 EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIRE-QEEKRQEQEEKMWKQEEKIREQEE 619
Query: 270 K-EDAAGTSGLGELNSREQ----TNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSV 324
K ++ E REQ Q + G+++++ +EEKM EE +E +
Sbjct: 620 KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEE--KI 677
Query: 325 RTEEVESRAYADPCSRRKKRQQQEEEDL 352
R +E + R + +++ Q++EE +
Sbjct: 678 REQEKKIREQEEKIREQEEMMQEQEEKM 705
Score = 38.5 bits (88), Expect = 0.010
Identities = 37/178 (20%), Positives = 81/178 (45%), Gaps = 16/178 (8%)
Query: 180 EAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAE 239
E +E+ + K ++ + + E K K+++K R Q+E+ + + + +EK E E
Sbjct: 581 EQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEE 640
Query: 240 QNIRKSKK-----KKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRK 294
+ +K +K QE K+ ++ E T E++ + E + + + + +
Sbjct: 641 MTQEQEEKMGEQEEKMCEQEEKMQEQEE-TMWRQEEKIREQEKKIREQEEKIREQEEMMQ 699
Query: 295 GKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDL 352
+++K W +EEKM EE ++ +E + R + ++ R +Q+EE +
Sbjct: 700 EQEEKMW-EQEEKMCEQEE---------KMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 747
Score = 37.7 bits (86), Expect = 0.017
Identities = 45/209 (21%), Positives = 96/209 (45%), Gaps = 29/209 (13%)
Query: 182 QEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASER-NDADEKHPEHAEQ 240
QEQ + R + + ++ + + ++++K R++EE+ E+ + +EK E E+
Sbjct: 473 QEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEK 532
Query: 241 NIRKSKK----------KKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQ 290
R+ +K +++ H++ K+ +E K E+ED E REQ +
Sbjct: 533 MWRQEEKIREQEEMWREEEKMHEQEKIWEEE----KRQEQEDKMWRQ---EEKIREQEEK 585
Query: 291 SLRKGKK----KKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQ 346
R+ +K +++ +EEKM EE K +E ++ +E + R + +++ Q
Sbjct: 586 VWRQEEKIREQEEKRQEQEEKMWKQEE--KIREQEEKIQEQEEKIREQEEKIREQEEMTQ 643
Query: 347 QEEEDLNLEDRGEETFRWWNQGSREQSMQ 375
++EE + GE+ + Q + Q +
Sbjct: 644 EQEEKM-----GEQEEKMCEQEEKMQEQE 667
>gi|33356179 transcription termination factor, RNA polymerase I
[Homo sapiens]
Length = 905
Score = 46.6 bits (109), Expect = 4e-05
Identities = 49/215 (22%), Positives = 88/215 (40%), Gaps = 36/215 (16%)
Query: 170 ITMKAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERND 229
++++ KL R + + F K + L S+ + K KK +R+ E A +
Sbjct: 130 MSIEQKLPR-KPKTDKFQVLAKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLP 188
Query: 230 ADEKH-----------------PEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEK-- 270
E H P A +N K KKKK ++E + EG+ G E
Sbjct: 189 QSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGT 248
Query: 271 --EDAAGTSGLGELNSR--EQTNQSLRKGKKKKRWHHEEEKMGVLEEGGK-GKEAAGSVR 325
+++ T GL + + T++ K KKKK+ +H+E + + EG + G E ++
Sbjct: 249 DMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQ 308
Query: 326 -----------TEEVESRAYADPCSRRKKRQQQEE 349
T + + AY + ++KK+ +E
Sbjct: 309 ESRPAVGLHGETAGIPAPAYKNKSKKKKKKSNHQE 343
Score = 39.7 bits (91), Expect = 0.004
Identities = 38/139 (27%), Positives = 55/139 (39%), Gaps = 34/139 (24%)
Query: 192 GQDPGAPQLQSESKPPKKKKKKRRQKEEEE-----------------ATASERNDADEKH 234
G D PQL + K KKKK+++ +E A E A H
Sbjct: 258 GLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGLH 317
Query: 235 ------PEHAEQNIRKSKKKKRRHQEGKV--------SDEREGTTKGNEKEDAAGTSGLG 280
P A +N K KKKK HQE + S EG+ G+E G++
Sbjct: 318 GETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTA-- 375
Query: 281 ELNSREQTNQSLRKGKKKK 299
L +++N + +K KK+K
Sbjct: 376 -LKGFKESNSTKKKSKKRK 393
Score = 32.0 bits (71), Expect = 0.93
Identities = 40/219 (18%), Positives = 87/219 (39%), Gaps = 31/219 (14%)
Query: 161 TAHKAARLGITMKAKLARLEAQEQAFLARL---------------KGQDPGAPQLQSESK 205
TA+ + L K + + LE E+A + + K D + E K
Sbjct: 76 TANATSTLKKRKKRRYSALEVDEEAGVTVVLVDKENINNTPKHFRKDVDVVCVDMSIEQK 135
Query: 206 PPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGT- 264
P+K K + Q ++ A + H++ +K+KK +R+ + R+
Sbjct: 136 LPRKPKTDKFQ-------VLAKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLP 188
Query: 265 -TKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGS 323
++ +++E GE+ + + KKKK+ + E + + EG + AG+
Sbjct: 189 QSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGT 248
Query: 324 VRTE-------EVESRAYADPCSRRKKRQQQEEEDLNLE 355
E + E+ P ++K +++++++ + E
Sbjct: 249 DMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQE 287
Score = 29.6 bits (65), Expect = 4.6
Identities = 27/134 (20%), Positives = 52/134 (38%), Gaps = 17/134 (12%)
Query: 180 EAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAE 239
+ QE L G+ G P ++K KKKKK Q+ E A A +PE ++
Sbjct: 306 DMQESRPAVGLHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESA---YPEGSQ 362
Query: 240 --------------QNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSR 285
+ ++S K++ ++ K++ + G++ + S +S
Sbjct: 363 VGSEVGTVEGSTALKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFDSV 422
Query: 286 EQTNQSLRKGKKKK 299
E + +G K +
Sbjct: 423 EGDGAMMEEGVKSR 436
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 46.6 bits (109), Expect = 4e-05
Identities = 41/202 (20%), Positives = 92/202 (45%), Gaps = 31/202 (15%)
Query: 173 KAKLARLEAQEQAFL------------ARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEE 220
+A+ ARLEA+E+ + AR++ ++ A Q + ++ +++ R +EEE
Sbjct: 266 EAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQ----ERERREAEERERMREEE 321
Query: 221 EATASERNDADEKHPEHAEQNIR-KSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGL 279
+ A ER E+ AE+ R K ++K+ + ++ +E + + ++
Sbjct: 322 KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQR--------- 372
Query: 280 GELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEV-ESRAYADPC 338
+R + + + ++K+ EE+K + E KG++ + + V E +A D
Sbjct: 373 ----ARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKL 428
Query: 339 SRRKKRQQQEEEDLNLEDRGEE 360
++Q EE+ ++ + E+
Sbjct: 429 QTAVLKKQGEEKGTKVQAKREK 450
Score = 42.0 bits (97), Expect = 9e-04
Identities = 52/209 (24%), Positives = 89/209 (42%), Gaps = 16/209 (7%)
Query: 131 LESCSDDDNQGSKSPKILTDEMLLQACEGRTAHKAARLGITMKAKLARLEAQEQAFLARL 190
LE+ + + + KI + ++A E A + R + ++ E + R+
Sbjct: 272 LEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRI 331
Query: 191 KGQDPGAPQLQSESKPPKKKKKKRRQ--KEEEEATASERNDADEKHPEHAEQNIRKSKK- 247
K ++ A + + K +K+ + RQ KEEE+ A ER A + E A+ +K K
Sbjct: 332 KEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQ 391
Query: 248 ---KKRRHQEGKVSDER-EGTTKG---NEK---EDAAGTSGLGELNSREQTNQSLRKGK- 296
KK QE K+ E+ E +G NEK ED T+ L + + T ++ K
Sbjct: 392 LEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKL 451
Query: 297 --KKKRWHHEEEKMGVLEEGGKGKEAAGS 323
K + EE K +++ + KE S
Sbjct: 452 QEDKPTFKKEEIKDEKIKKDKEPKEEVKS 480
Score = 39.3 bits (90), Expect = 0.006
Identities = 38/172 (22%), Positives = 74/172 (43%), Gaps = 15/172 (8%)
Query: 201 QSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQE----GK 256
++E+ ++K + R+++ E E T + + AE+N ++ K+K+ +E G
Sbjct: 143 ENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGS 202
Query: 257 VSDER-----EGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHH---EEEKM 308
+ + + E T +++E + G+++S E + R+ + HH EEE
Sbjct: 203 IGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDK 262
Query: 309 GVLEEGGKGKEAAGSVRTEEVESRAYADPCSR---RKKRQQQEEEDLNLEDR 357
E EA R + + + AD +R +K QE E E+R
Sbjct: 263 ERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEER 314
Score = 39.3 bits (90), Expect = 0.006
Identities = 40/184 (21%), Positives = 83/184 (45%), Gaps = 31/184 (16%)
Query: 180 EAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAE 239
E+QE+ + LK Q+ SE + K+++ R++ +E + E+ + ++K AE
Sbjct: 218 ESQEETVVMSLKNG-----QISSE----EPKQEEEREQGSDEISHHEKMEEEDKERAEAE 268
Query: 240 QNIRKSKKKKR--RHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKK 297
+ ++++++R Q+ K++DER E E+ A RE+ R+ ++
Sbjct: 269 RARLEAEERERIKAEQDKKIADERARI----EAEEKAAAQ------ERER-----REAEE 313
Query: 298 KKRWHHE-----EEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDL 352
++R E EE+ + EE + E ++ EE + +KR +E +
Sbjct: 314 RERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRA 373
Query: 353 NLED 356
E+
Sbjct: 374 RAEE 377
Score = 35.8 bits (81), Expect = 0.064
Identities = 33/164 (20%), Positives = 82/164 (50%), Gaps = 19/164 (11%)
Query: 208 KKKKKKRRQKEEE-----EATASERNDADEKHPEHAEQNIRKSKKKKRRHQE-----GKV 257
+++++ RRQK EE E A +RND DE+ E A + R++++++ R ++ G+V
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEE--EAARERRRRARQERLRQKQEEESLGQV 62
Query: 258 SDEREGTTKGNEKEDAAGTSGL-----GELNSREQTNQSLRKGKKKKRWHHEEEKMGVLE 312
+D+ E + + ++ A T+ G+ + + R+ +++KR E+ E
Sbjct: 63 TDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQ--KE 120
Query: 313 EGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLED 356
+A+ S+ + +++ + + ++++ + +E +E+
Sbjct: 121 FDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEE 164
Score = 32.7 bits (73), Expect = 0.55
Identities = 28/121 (23%), Positives = 54/121 (44%), Gaps = 4/121 (3%)
Query: 178 RLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEH 237
R E + + F + Q A +L+ KKK+++RR+ EEE ++ +AD K E
Sbjct: 543 RGETESEEFEKLKQKQQEAALELEEL----KKKREERRKVLEEEEQRRKQEEADRKLREE 598
Query: 238 AEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKK 297
E+ K + ++RR + + + ++K+ + G E+ + L K +
Sbjct: 599 EEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQ 658
Query: 298 K 298
K
Sbjct: 659 K 659
Score = 29.3 bits (64), Expect = 6.0
Identities = 36/189 (19%), Positives = 69/189 (36%), Gaps = 12/189 (6%)
Query: 175 KLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKH 234
+LAR E + Q L + +++ ++ + E E T E +
Sbjct: 99 RLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQE 158
Query: 235 PEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLG----ELNSREQTNQ 290
E+ +K ++ +++E K E+E+ +G E+ E+T +
Sbjct: 159 RYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTE 218
Query: 291 SLRK----GKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQ 346
S + K + EE K E G + + EE + RA A+ R + +
Sbjct: 219 SQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAE----RARLEA 274
Query: 347 QEEEDLNLE 355
+E E + E
Sbjct: 275 EERERIKAE 283
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.125 0.353
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,537,026
Number of Sequences: 37866
Number of extensions: 767382
Number of successful extensions: 13587
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 389
Number of HSP's successfully gapped in prelim test: 601
Number of HSP's that attempted gapping in prelim test: 5928
Number of HSP's gapped (non-prelim): 4184
length of query: 375
length of database: 18,247,518
effective HSP length: 104
effective length of query: 271
effective length of database: 14,309,454
effective search space: 3877862034
effective search space used: 3877862034
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.