Search of human proteins with 122939151

Search of human proteins with 122939151

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|122939151 Rho GTPase activating protein 9 isoform 2 [Homo
sapiens]
         (640 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|122939151 Rho GTPase activating protein 9 isoform 2 [Homo sap...  1303   0.0  
gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sap...  1301   0.0  
gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sap...   928   0.0  
gi|188497642 ARHGAP15 [Homo sapiens]                                  255   8e-68
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]           239   4e-63
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap...   236   4e-62
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa...   235   1e-61
gi|23510413 sorting nexin 26 [Homo sapiens]                            85   2e-16
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]           80   4e-15
gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]    79   2e-14
gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]     74   3e-13
gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo sap...    68   2e-11
gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sap...    68   2e-11
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]             66   9e-11
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]           66   9e-11
gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sap...    65   1e-10
gi|229094128 active breakpoint cluster region-related  protein i...    65   3e-10
gi|38679957 active breakpoint cluster region-related  protein is...    65   3e-10
gi|38679954 active breakpoint cluster region-related  protein is...    65   3e-10
gi|149274655 synapse defective 1, Rho GTPase, homolog 2 [Homo sa...    64   4e-10
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]           62   1e-09
gi|4757980 beta chimerin isoform 2 [Homo sapiens]                      62   2e-09
gi|91106928 beta chimerin isoform 1 [Homo sapiens]                     62   2e-09
gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]         61   3e-09
gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]         61   4e-09
gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens]                58   3e-08
gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo sapi...    58   3e-08
gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo sapi...    58   3e-08
gi|5803145 ralA binding protein 1 [Homo sapiens]                       57   7e-08
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]            57   7e-08

>gi|122939151 Rho GTPase activating protein 9 isoform 2 [Homo
           sapiens]
          Length = 640

 Score = 1303 bits (3373), Expect = 0.0
 Identities = 640/640 (100%), Positives = 640/640 (100%)

Query: 1   MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD 60
           MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD
Sbjct: 1   MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD 60

Query: 61  WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA 120
           WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA
Sbjct: 61  WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA 120

Query: 121 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG 180
           LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG
Sbjct: 121 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG 180

Query: 181 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK 240
           PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK
Sbjct: 181 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK 240

Query: 241 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS 300
           SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS
Sbjct: 241 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS 300

Query: 301 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY 360
           QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY
Sbjct: 301 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY 360

Query: 361 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE 420
           REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE
Sbjct: 361 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE 420

Query: 421 TELRAWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRS 480
           TELRAWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRS
Sbjct: 421 TELRAWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRS 480

Query: 481 SIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL 540
           SIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL
Sbjct: 481 SIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL 540

Query: 541 RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL 600
           RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL
Sbjct: 541 RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL 600

Query: 601 DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALG 640
           DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALG
Sbjct: 601 DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALG 640


>gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo
           sapiens]
          Length = 731

 Score = 1301 bits (3367), Expect = 0.0
 Identities = 639/639 (100%), Positives = 639/639 (100%)

Query: 1   MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD 60
           MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD
Sbjct: 1   MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD 60

Query: 61  WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA 120
           WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA
Sbjct: 61  WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA 120

Query: 121 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG 180
           LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG
Sbjct: 121 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG 180

Query: 181 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK 240
           PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK
Sbjct: 181 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK 240

Query: 241 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS 300
           SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS
Sbjct: 241 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS 300

Query: 301 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY 360
           QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY
Sbjct: 301 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY 360

Query: 361 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE 420
           REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE
Sbjct: 361 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE 420

Query: 421 TELRAWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRS 480
           TELRAWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRS
Sbjct: 421 TELRAWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRS 480

Query: 481 SIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL 540
           SIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL
Sbjct: 481 SIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL 540

Query: 541 RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL 600
           RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL
Sbjct: 541 RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL 600

Query: 601 DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 639
           DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL
Sbjct: 601 DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 639


>gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo
           sapiens]
          Length = 547

 Score =  928 bits (2398), Expect = 0.0
 Identities = 455/455 (100%), Positives = 455/455 (100%)

Query: 185 MSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKP 244
           MSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKP
Sbjct: 1   MSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKP 60

Query: 245 PRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTSQLDP 304
           PRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTSQLDP
Sbjct: 61  PRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTSQLDP 120

Query: 305 PALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFYREPP 364
           PALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFYREPP
Sbjct: 121 PALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFYREPP 180

Query: 365 PTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHETELR 424
           PTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHETELR
Sbjct: 181 PTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHETELR 240

Query: 425 AWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRG 484
           AWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRG
Sbjct: 241 AWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRG 300

Query: 485 PEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCI 544
           PEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCI
Sbjct: 301 PEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCI 360

Query: 545 AAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTE 604
           AAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTE
Sbjct: 361 AAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTE 420

Query: 605 WDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 639
           WDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL
Sbjct: 421 WDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 455


>gi|188497642 ARHGAP15 [Homo sapiens]
          Length = 475

 Score =  255 bits (652), Expect = 8e-68
 Identities = 149/337 (44%), Positives = 208/337 (61%), Gaps = 40/337 (11%)

Query: 312 PLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSG 371
           PL QL+     VEK G L   KIA GG+KLRKNW  SW+VL+   + FY+E    A S+ 
Sbjct: 74  PLEQLM-----VEKEGYLQKAKIADGGKKLRKNWSTSWIVLSSRRIEFYKESKQQALSNM 128

Query: 372 WGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALR 431
               G +PES VDL GA +   +  SSR+NV  I T+ G+EFLLQSD +  +  W  A++
Sbjct: 129 --KTGHKPES-VDLCGAHIEWAKEKSSRKNVFQITTVSGNEFLLQSDIDFIILDWFHAIK 185

Query: 432 TVIERLDRENP-----LEL-RLSGSGPAELSAGED---EEEESELVSKPLLRLSSRRSSI 482
             I+RL +++      LEL ++  S   EL +  D   +E++ E     + RL    S  
Sbjct: 186 NAIDRLPKDSSCPSRNLELFKIQRSSSTELLSHYDSDIKEQKPEHRKSLMFRLHHSAS-- 243

Query: 483 RGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRL 542
              + +++NRV+++LK+ I +RP L++LQE+GL++DQ+FG  L  +C+RE  TVP F++ 
Sbjct: 244 ---DTSDKNRVKSRLKKFITRRPSLKTLQEKGLIKDQIFGSHLHKVCERENSTVPWFVKQ 300

Query: 543 CIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDS 602
           CI AV+KRGLDVDGIYRVSGNLA +QKLRF+V+                  QE +L+LD 
Sbjct: 301 CIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVN------------------QEEKLNLDD 342

Query: 603 TEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 639
           ++W+DIHVVTGALK+F RELP+PL P      F  A+
Sbjct: 343 SQWEDIHVVTGALKMFFRELPEPLFPYSFFEQFVEAI 379


>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
          Length = 846

 Score =  239 bits (611), Expect = 4e-63
 Identities = 150/416 (36%), Positives = 237/416 (56%), Gaps = 42/416 (10%)

Query: 217 DAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKG 276
           + W +H+D + GR +Y ++      W+ P+ + S      +  +++L R         K 
Sbjct: 362 EKWLKHVD-DQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTK- 419

Query: 277 FRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLD---DPHEVEKSGLLNMTK 333
           +R  T   +  D +     S   S+   P  ++    P+  D    P + EK GLLN+TK
Sbjct: 420 WRHSTIVLDTNDKE-----SPTASKPCFPENESSPSSPKHQDTASSPKDQEKYGLLNVTK 474

Query: 334 IAQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHG 393
           IA+ G+K+RKNW  SW VL G+SL+F +    +  +S +G   S+PE +VDL+GA +   
Sbjct: 475 IAENGKKVRKNWLSSWAVLQGSSLLFTKTQGSS--TSWFGSNQSKPEFTVDLKGATIEMA 532

Query: 394 -RHLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVI--ERLDRENPLELRLSGS 450
            +  SS++NV  ++T  G E L+QSD++T +  W + L + I  + ++ +  +E  +  S
Sbjct: 533 SKDKSSKKNVFELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQAVETDEGIEEEIPDS 592

Query: 451 GPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSL 510
              E    E E+++      P    S + SSI   + +EQ + +  LK+ + +RP LQ++
Sbjct: 593 PGIEKHDKEKEQKD------PKKLRSFKVSSI---DSSEQKKTKKNLKKFLTRRPTLQAV 643

Query: 511 QERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKL 570
           +E+G ++DQVFG  L +LCQRE  TVP F++LCI  V++ GLD+DGIYRVSGNLAV+QKL
Sbjct: 644 REKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKL 703

Query: 571 RFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPL 626
           RF V+ +                   +LDL+ ++W+DIHV+TGALK+F RELP+PL
Sbjct: 704 RFAVNHDE------------------KLDLNDSKWEDIHVITGALKMFFRELPEPL 741



 Score = 66.2 bits (160), Expect = 9e-11
 Identities = 42/122 (34%), Positives = 58/122 (47%), Gaps = 10/122 (8%)

Query: 144 STDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRS 203
           S D+      +  Q+  SG  LS     +E   +T  P     + PVY NL +L+    +
Sbjct: 198 SCDSAGEGSERIHQDSESGDELSSSS--TEQIRATTPPNQGRPDSPVYANLQELKISQSA 255

Query: 204 PPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSET-------NPGS 256
            PP P  P +Q    WE H D +SGRC+Y N  T  ++WKPPR +R  +       NPG 
Sbjct: 256 LPPLPGSPAIQINGEWETHKD-SSGRCYYYNRGTQERTWKPPRWTRDASISKGDFQNPGD 314

Query: 257 ME 258
            E
Sbjct: 315 QE 316



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 18/55 (32%), Positives = 35/55 (63%), Gaps = 4/55 (7%)

Query: 31 YAFTYTGADGQQVSLAEGDRFLLLRKTNSDWWLARRLEAPSTSRPIFVPAAYMIE 85
          Y + Y   D +++ + +G+R++L++KTN DWW   +++    S+  +VPA Y+ E
Sbjct: 21 YDYEYEAKD-RKIVIKQGERYILVKKTNDDWW---QVKPDENSKAFYVPAQYVKE 71


>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
           sapiens]
          Length = 548

 Score =  236 bits (603), Expect = 4e-62
 Identities = 161/456 (35%), Positives = 235/456 (51%), Gaps = 75/456 (16%)

Query: 201 PRSPPPGPACPLLQ----------RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRS 250
           P + PPG +C + Q            + W +  DP+ G+ ++ N       W+ P+    
Sbjct: 48  PLTTPPGWSCHVSQDKQMLYTNHFTQEQWVRLEDPH-GKPYFYNPEDSSVRWELPQVP-- 104

Query: 251 ETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAP 310
                 +   +++ +++      A+    +   P  LD  GS            PA  A 
Sbjct: 105 ------VPAPRSIHKSSQDGDTPAQASPPEEKVPAELDEVGSWEEVS-------PATAAV 151

Query: 311 RPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRK-NWGPSWVVLTGNSLVFYREPPPTAPS 369
           R           ++K+G+L+ TK A  G++LRK +W  SW VL G  L F+++   +A  
Sbjct: 152 RT--------KTLDKAGVLHRTKTADKGKRLRKKHWSASWTVLEGGVLTFFKDSKTSAAG 203

Query: 370 SGWGPAG-SRPESSVDLRGAALAHG-RHLSSRRNVLHIRTIPGHEFLLQSDHETELRAWH 427
               P+  S PE +V+LRGA L+   +  SSR+NVL +R+  G E+L+Q D E  +  WH
Sbjct: 204 GLRQPSKFSTPEYTVELRGATLSWAPKDKSSRKNVLELRSRDGSEYLIQHDSEAIISTWH 263

Query: 428 RALRTVIERLDRENPLELRLS-----GSGPAELSAGEDEEEESELVSKPLLRLSSRRSSI 482
           +A+   I+ L  E P E   S     GS     S  E EE+     + P L         
Sbjct: 264 KAIAQGIQELSAELPPEESESSRVDFGSSERLGSWQEKEEDARPNAAAPAL--------- 314

Query: 483 RGPEGTEQN--RVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL 540
            GP G E +  +VR+KL++ + +RP LQSL+E+G ++DQVFGC L +LC+RE   VP F+
Sbjct: 315 -GPVGLESDLSKVRHKLRKFLQRRPTLQSLREKGYIKDQVFGCALAALCERERSRVPRFV 373

Query: 541 RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL 600
           + CI AV+ RGLD+DG+YR+SGNLA +QKLR+ VD +                   RLDL
Sbjct: 374 QQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHDE------------------RLDL 415

Query: 601 DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFR 636
           D   W+D+HV+TGALKLF RELP+PL P     HFR
Sbjct: 416 DDGRWEDVHVITGALKLFFRELPEPLFP---FSHFR 448


>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
           sapiens]
          Length = 521

 Score =  235 bits (599), Expect = 1e-61
 Identities = 138/324 (42%), Positives = 192/324 (59%), Gaps = 41/324 (12%)

Query: 323 VEKSGLLNMTKIAQGGRKLRK-NWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAG-SRPE 380
           ++K+G+L+ TK A  G++LRK +W  SW VL G  L F+++   +A      P+  S PE
Sbjct: 129 LDKAGVLHRTKTADKGKRLRKKHWSASWTVLEGGVLTFFKDSKTSAAGGLRQPSKFSTPE 188

Query: 381 SSVDLRGAALAHG-RHLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLDR 439
            +V+LRGA L+   +  SSR+NVL +R+  G E+L+Q D E  +  WH+A+   I+ L  
Sbjct: 189 YTVELRGATLSWAPKDKSSRKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAQGIQELSA 248

Query: 440 ENPLELRLS-----GSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQN--R 492
           E P E   S     GS     S  E EE+     + P L          GP G E +  +
Sbjct: 249 ELPPEESESSRVDFGSSERLGSWQEKEEDARPNAAAPAL----------GPVGLESDLSK 298

Query: 493 VRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGL 552
           VR+KL++ + +RP LQSL+E+G ++DQVFGC L +LC+RE   VP F++ CI AV+ RGL
Sbjct: 299 VRHKLRKFLQRRPTLQSLREKGYIKDQVFGCALAALCERERSRVPRFVQQCIRAVEARGL 358

Query: 553 DVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVT 612
           D+DG+YR+SGNLA +QKLR+ VD +                   RLDLD   W+D+HV+T
Sbjct: 359 DIDGLYRISGNLATIQKLRYKVDHDE------------------RLDLDDGRWEDVHVIT 400

Query: 613 GALKLFLRELPQPLVPPLLLPHFR 636
           GALKLF RELP+PL P     HFR
Sbjct: 401 GALKLFFRELPEPLFP---FSHFR 421


>gi|23510413 sorting nexin 26 [Homo sapiens]
          Length = 1126

 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 58/165 (35%), Positives = 80/165 (48%), Gaps = 22/165 (13%)

Query: 475 LSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGD 534
           +SS  S++  P G    ++   L+  +  RP  Q L++RG+LR +VFGC L       G 
Sbjct: 271 ISSLTSAVPRPRG----KLAGLLRTFMRSRPSRQRLRQRGILRQRVFGCDLGEHLSNSGQ 326

Query: 535 TVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQ 594
            VP  LR C   ++  G+ VDGIYR+SG  + +Q+LR   D ER          PE  G 
Sbjct: 327 DVPQVLRCCSEFIEAHGV-VDGIYRLSGVSSNIQRLRHEFDSER---------IPELSG- 375

Query: 595 EGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 639
                       DIH V+   KL+ RELP PL+   L   F  A+
Sbjct: 376 -------PAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSEAM 413


>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
          Length = 1397

 Score = 80.5 bits (197), Expect = 4e-15
 Identities = 80/301 (26%), Positives = 130/301 (43%), Gaps = 38/301 (12%)

Query: 343 KNWGPSWVVLTGNSLVFY---REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSR 399
           + W   +  L   SL      REP P A  +    AG    + V +    +      + R
Sbjct: 619 RQWKRVYAALRARSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKR 678

Query: 400 RNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLDRENP-------LELRLSGSGP 452
           R+V  + T    E+L Q++   ++  W RA+R    R + E+P       +  +L+    
Sbjct: 679 RHVFRLTTADFCEYLFQAEDRDDMLGWIRAIREN-SRAEGEDPGCANQALISKKLNDYRK 737

Query: 453 AELSAGEDEEEESELVSKPLLRLSS---RRSSIRGPEGTEQNRVRNKLKRLIAKRPP--L 507
              S+G  + + S   S+ L  L S   ++S+ RG   T+     +K     A + P  +
Sbjct: 738 VSHSSGP-KADSSPKGSRGLGGLKSEFLKQSAARGLR-TQDLPAGSKDDSAAAPKTPWGI 795

Query: 508 QSLQERGLLRDQVFGCQLESLCQ--REGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLA 565
             +++      + FG +LE  CQ   E   VP  +  C   V+ RGL+  GIYRV GN A
Sbjct: 796 NIIKKNKKAAPRAFGVRLEE-CQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNA 854

Query: 566 VVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQP 625
           VV  L+  ++R                   G ++L    W D++V++  LK F R+LP+P
Sbjct: 855 VVSSLQEQLNR-----------------GPGDINLQDERWQDLNVISSLLKSFFRKLPEP 897

Query: 626 L 626
           L
Sbjct: 898 L 898


>gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]
          Length = 2087

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 52/161 (32%), Positives = 78/161 (48%), Gaps = 20/161 (12%)

Query: 480 SSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSF 539
           +S+  P   +  ++   L+  +  RP  Q L++RG+L+++VFGC L       G  VP  
Sbjct: 329 NSVPKPVSKKHGKLITFLRTFMKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQV 388

Query: 540 LRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLD 599
           L+ C A +++ G+ VDGIYR+SG  + +Q+LR   D E                     D
Sbjct: 389 LQSCTAFIERYGI-VDGIYRLSGVASNIQRLRHEFDSEHVP------------------D 429

Query: 600 LDSTEW-DDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 639
           L    +  DIH V    KL+ RELP PL+   L   F  A+
Sbjct: 430 LTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAV 470


>gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]
          Length = 1738

 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 49/137 (35%), Positives = 68/137 (49%), Gaps = 20/137 (14%)

Query: 504 RPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGN 563
           RP  Q L++RG+L+++VFGC L       G  VP  L+ C A +++ G+ VDGIYR+SG 
Sbjct: 4   RPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGI-VDGIYRLSGV 62

Query: 564 LAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEW-DDIHVVTGALKLFLREL 622
            + +Q+LR   D E                     DL    +  DIH V    KL+ REL
Sbjct: 63  ASNIQRLRHEFDSEHVP------------------DLTKEPYVQDIHSVGSLCKLYFREL 104

Query: 623 PQPLVPPLLLPHFRAAL 639
           P PL+   L   F  A+
Sbjct: 105 PNPLLTYQLYEKFSDAV 121


>gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo
           sapiens]
          Length = 890

 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 46/133 (34%), Positives = 67/133 (50%), Gaps = 18/133 (13%)

Query: 508 QSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVV 567
           Q  +++G  +++VFGC L+   Q  G  VP  L+ C   V++ G+ VDGIYR+SG  + +
Sbjct: 5   QKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGV-VDGIYRLSGVSSNI 63

Query: 568 QKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLV 627
           QKLR   + ER            +P     + L      DIH V+   K + RELP PL+
Sbjct: 64  QKLRQEFESER------------KPDLRRDVYL-----QDIHCVSSLCKAYFRELPDPLL 106

Query: 628 PPLLLPHFRAALG 640
              L   F  A+G
Sbjct: 107 TYRLYDKFAEAVG 119


>gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo
           sapiens]
          Length = 1101

 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 46/133 (34%), Positives = 67/133 (50%), Gaps = 18/133 (13%)

Query: 508 QSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVV 567
           Q  +++G  +++VFGC L+   Q  G  VP  L+ C   V++ G+ VDGIYR+SG  + +
Sbjct: 5   QKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGV-VDGIYRLSGVSSNI 63

Query: 568 QKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLV 627
           QKLR   + ER            +P     + L      DIH V+   K + RELP PL+
Sbjct: 64  QKLRQEFESER------------KPDLRRDVYL-----QDIHCVSSLCKAYFRELPDPLL 106

Query: 628 PPLLLPHFRAALG 640
              L   F  A+G
Sbjct: 107 TYRLYDKFAEAVG 119


>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
          Length = 459

 Score = 66.2 bits (160), Expect = 9e-11
 Identities = 36/117 (30%), Positives = 62/117 (52%), Gaps = 17/117 (14%)

Query: 519 QVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRER 578
           +V+ C L +L +      P  + +CI  ++ RGL+ +G+YRVSG   +++ ++   DR  
Sbjct: 264 KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDR-- 321

Query: 579 AVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHF 635
               DG            + D+    ++DI+++TGALKL+ R+LP PL+     P F
Sbjct: 322 ----DGE-----------KADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKF 363


>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
          Length = 433

 Score = 66.2 bits (160), Expect = 9e-11
 Identities = 36/117 (30%), Positives = 62/117 (52%), Gaps = 17/117 (14%)

Query: 519 QVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRER 578
           +V+ C L +L +      P  + +CI  ++ RGL+ +G+YRVSG   +++ ++   DR  
Sbjct: 238 KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDR-- 295

Query: 579 AVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHF 635
               DG            + D+    ++DI+++TGALKL+ R+LP PL+     P F
Sbjct: 296 ----DGE-----------KADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKF 337


>gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo
           sapiens]
          Length = 735

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 46/142 (32%), Positives = 73/142 (51%), Gaps = 20/142 (14%)

Query: 489 EQNRVRNKLKRLIAKRPPLQSLQERGLLRD-QVFGCQLESLCQREGDT--VPSFLRLCIA 545
           +Q  VR + + L+  +  L   QE     + +VFG  L  L +RE     VP  ++ C+ 
Sbjct: 363 QQLAVRLEPQGLLYAKLTLSEQQEAPATAEPRVFGLPLPLLVERERPPGQVPLIIQKCVG 422

Query: 546 AVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEW 605
            +++RGL V G+YR+ G+ AV ++LR   +R+ A       ++P                
Sbjct: 423 QIERRGLRVVGLYRLCGSAAVKKELRDAFERDSAAVCLSEDLYP---------------- 466

Query: 606 DDIHVVTGALKLFLRELPQPLV 627
            DI+V+TG LK +LRELP PL+
Sbjct: 467 -DINVITGILKDYLRELPTPLI 487


>gi|229094128 active breakpoint cluster region-related  protein
           isoform c [Homo sapiens]
          Length = 813

 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 39/116 (33%), Positives = 59/116 (50%), Gaps = 18/116 (15%)

Query: 520 VFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERA 579
           VFG ++  + +RE   VP  +R C+  V+KRG++  GIYR+SG    +Q L+ + D   A
Sbjct: 598 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFD---A 654

Query: 580 VTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHF 635
              D   +  +                DI+ + G LKL+ RELP+PL+   L P F
Sbjct: 655 NNKDILLMLSDM---------------DINAIAGTLKLYFRELPEPLLTDRLYPAF 695


>gi|38679957 active breakpoint cluster region-related  protein
           isoform a [Homo sapiens]
          Length = 859

 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 39/116 (33%), Positives = 59/116 (50%), Gaps = 18/116 (15%)

Query: 520 VFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERA 579
           VFG ++  + +RE   VP  +R C+  V+KRG++  GIYR+SG    +Q L+ + D   A
Sbjct: 644 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFD---A 700

Query: 580 VTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHF 635
              D   +  +                DI+ + G LKL+ RELP+PL+   L P F
Sbjct: 701 NNKDILLMLSDM---------------DINAIAGTLKLYFRELPEPLLTDRLYPAF 741


>gi|38679954 active breakpoint cluster region-related  protein
           isoform b [Homo sapiens]
          Length = 822

 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 39/116 (33%), Positives = 59/116 (50%), Gaps = 18/116 (15%)

Query: 520 VFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERA 579
           VFG ++  + +RE   VP  +R C+  V+KRG++  GIYR+SG    +Q L+ + D   A
Sbjct: 607 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFD---A 663

Query: 580 VTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHF 635
              D   +  +                DI+ + G LKL+ RELP+PL+   L P F
Sbjct: 664 NNKDILLMLSDM---------------DINAIAGTLKLYFRELPEPLLTDRLYPAF 704


>gi|149274655 synapse defective 1, Rho GTPase, homolog 2 [Homo
           sapiens]
          Length = 1194

 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 36/110 (32%), Positives = 60/110 (54%), Gaps = 19/110 (17%)

Query: 520 VFGCQLESLCQRE--GDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRE 577
           +FG  ++ + ++E  G  VP  ++ CI  ++KRG  V G+YR+ G+ AV ++LR   +R+
Sbjct: 813 IFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFERD 872

Query: 578 RAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLV 627
                               + L   ++ DI+V+TG LK +LRELP PL+
Sbjct: 873 SKA-----------------VGLCENQYPDINVITGVLKDYLRELPSPLI 905


>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
          Length = 1958

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 65/310 (20%), Positives = 126/310 (40%), Gaps = 61/310 (19%)

Query: 345  WGPSWVVLTGNSLVFYREP-PPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVL 403
            W   +VVL G+SL  Y++    T PS          E  + +    +      + R+NV 
Sbjct: 958  WKQMYVVLRGHSLYLYKDKREQTTPSE--------EEQPISVNACLIDISYSETKRKNVF 1009

Query: 404  HIRTIPGHEFLLQSDHETELRAWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEE- 462
             + T    E L Q++   ++ AW       I+ +   + L    +G    +L +   +E 
Sbjct: 1010 RLTT-SDCECLFQAEDRDDMLAW-------IKTIQESSNLNEEDTGVTNRDLISRRIKEY 1061

Query: 463  -----EESELVSKPLLRLSSRRSSIRG---PEGTEQNRVRNKLKRLIAKRPPLQSLQERG 514
                 +  +L   P   LS R++ +     P+    +  + + +R +  +      +++G
Sbjct: 1062 NNLMSKAEQLPKTPRQSLSIRQTLLGAKSEPKTQSPHSPKEESERKLLSKDDTSPPKDKG 1121

Query: 515  LLRDQV-----------------FGCQLESLCQREGDT-VPSFLRLCIAAVDKRGLDVDG 556
              R  +                 FG +L+       +  +P  + +C   V++RGL+  G
Sbjct: 1122 TWRKGIPSIMRKTFEKKPTATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTG 1181

Query: 557  IYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALK 616
            IYRV GN A +  ++  +++  A                  +D+   +W D++V++  LK
Sbjct: 1182 IYRVPGNNAAISSMQEELNKGMA-----------------DIDIQDDKWRDLNVISSLLK 1224

Query: 617  LFLRELPQPL 626
             F R+LP+PL
Sbjct: 1225 SFFRKLPEPL 1234


>gi|4757980 beta chimerin isoform 2 [Homo sapiens]
          Length = 468

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 33/109 (30%), Positives = 58/109 (53%), Gaps = 17/109 (15%)

Query: 519 QVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRER 578
           +V+ C L +L +      P  + +CI  ++ RGL  +G+YRVSG    ++ ++   DR  
Sbjct: 273 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR-- 330

Query: 579 AVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLV 627
               DG            + D+ +  + DI+++TGALKL+ R+LP P++
Sbjct: 331 ----DGE-----------KADISANVYPDINIITGALKLYFRDLPIPVI 364


>gi|91106928 beta chimerin isoform 1 [Homo sapiens]
          Length = 332

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 33/109 (30%), Positives = 58/109 (53%), Gaps = 17/109 (15%)

Query: 519 QVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRER 578
           +V+ C L +L +      P  + +CI  ++ RGL  +G+YRVSG    ++ ++   DR  
Sbjct: 137 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR-- 194

Query: 579 AVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLV 627
               DG            + D+ +  + DI+++TGALKL+ R+LP P++
Sbjct: 195 ----DGE-----------KADISANVYPDINIITGALKLYFRDLPIPVI 228


>gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]
          Length = 1271

 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 49/180 (27%), Positives = 81/180 (45%), Gaps = 23/180 (12%)

Query: 459  EDEEEESELVSKPLLRLSSRRSSIRGPEGT--EQNRVRNKLK-RLIAKRPPLQSLQERGL 515
            ED E    L+ K  ++L  +    R  + T    N +  KL  +  ++   L+ +  R  
Sbjct: 989  EDGESTDRLMGKGQVQLDPQALQDRDWQRTVIAMNGIEVKLSVKFNSREFSLKRMPSRK- 1047

Query: 516  LRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVD 575
             +  VFG ++  + +RE   VP  +R C+  +++RG++  GIYRVSG    +Q L+   D
Sbjct: 1048 -QTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFD 1106

Query: 576  RERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHF 635
                   D   +  E                D++ + G LKL+ RELP+PL      P+F
Sbjct: 1107 ---VNNKDVSVMMSEM---------------DVNAIAGTLKLYFRELPEPLFTDEFYPNF 1148


>gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]
          Length = 1227

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 36/116 (31%), Positives = 56/116 (48%), Gaps = 18/116 (15%)

Query: 520  VFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERA 579
            VFG ++  + +RE   VP  +R C+  +++RG++  GIYRVSG    +Q L+   D    
Sbjct: 1007 VFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFD---V 1063

Query: 580  VTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHF 635
               D   +  E                D++ + G LKL+ RELP+PL      P+F
Sbjct: 1064 NNKDVSVMMSEM---------------DVNAIAGTLKLYFRELPEPLFTDEFYPNF 1104


>gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens]
          Length = 555

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 41/139 (29%), Positives = 69/139 (49%), Gaps = 23/139 (16%)

Query: 492 RVRNKLKRLIAKR--PPLQSLQERGLLRDQVFGCQLESLCQR-EGDTVPSFLRLCIAAVD 548
           R   KL+ L   R  PP ++   R  L  Q FG  L+ L  + +G+ +P  LR  +  + 
Sbjct: 284 RYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLR 343

Query: 549 KRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDI 608
           ++GL  +G++R S ++  V++++ L ++ + V  D                    ++ DI
Sbjct: 344 EKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFD--------------------DYGDI 383

Query: 609 HVVTGALKLFLRELPQPLV 627
           H+    LK FLRELPQPL+
Sbjct: 384 HIPAVILKTFLRELPQPLL 402


>gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo
           sapiens]
          Length = 433

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 41/139 (29%), Positives = 69/139 (49%), Gaps = 23/139 (16%)

Query: 492 RVRNKLKRLIAKR--PPLQSLQERGLLRDQVFGCQLESLCQR-EGDTVPSFLRLCIAAVD 548
           R   KL+ L   R  PP ++   R  L  Q FG  L+ L  + +G+ +P  LR  +  + 
Sbjct: 162 RYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLR 221

Query: 549 KRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDI 608
           ++GL  +G++R S ++  V++++ L ++ + V  D                    ++ DI
Sbjct: 222 EKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFD--------------------DYGDI 261

Query: 609 HVVTGALKLFLRELPQPLV 627
           H+    LK FLRELPQPL+
Sbjct: 262 HIPAVILKTFLRELPQPLL 280


>gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo
           sapiens]
          Length = 464

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 41/139 (29%), Positives = 69/139 (49%), Gaps = 23/139 (16%)

Query: 492 RVRNKLKRLIAKR--PPLQSLQERGLLRDQVFGCQLESLCQR-EGDTVPSFLRLCIAAVD 548
           R   KL+ L   R  PP ++   R  L  Q FG  L+ L  + +G+ +P  LR  +  + 
Sbjct: 193 RYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLR 252

Query: 549 KRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDI 608
           ++GL  +G++R S ++  V++++ L ++ + V  D                    ++ DI
Sbjct: 253 EKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFD--------------------DYGDI 292

Query: 609 HVVTGALKLFLRELPQPLV 627
           H+    LK FLRELPQPL+
Sbjct: 293 HIPAVILKTFLRELPQPLL 311


>gi|5803145 ralA binding protein 1 [Homo sapiens]
          Length = 655

 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 50/186 (26%), Positives = 80/186 (43%), Gaps = 32/186 (17%)

Query: 461 EEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQV 520
           EE+  E   K       +   +   +  +Q + + K K+ I + P +  +    L    +
Sbjct: 133 EEKHKEEKHKEEKHKEKKSKDLTAADVVKQWKEKKKKKKPI-QEPEVPQIDVPNL--KPI 189

Query: 521 FGCQLESLCQR----EGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDR 576
           FG  L    +R    +G  +P+  R CI  V+K G+  +GIYRVSG  + V +L+   DR
Sbjct: 190 FGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAYDR 249

Query: 577 ERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDI--HVVTGALKLFLRELPQPLVPPLLLPH 634
           E                       +ST  +D   + V   LK +LR+LP+ L+   L+P 
Sbjct: 250 E-----------------------ESTNLEDYEPNTVASLLKQYLRDLPENLLTKELMPR 286

Query: 635 FRAALG 640
           F  A G
Sbjct: 287 FEEACG 292


>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
          Length = 1444

 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 42/133 (31%), Positives = 60/133 (45%), Gaps = 22/133 (16%)

Query: 508 QSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVV 567
           Q L+ +G      FGC L    +  G  VP  L+ C   ++  G+ VDGIYR+SG  + +
Sbjct: 8   QKLKRKGAA--SAFGCDLTEYLESSGQDVPYVLKSCAEFIETHGI-VDGIYRLSGVTSNI 64

Query: 568 QKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEW-DDIHVVTGALKLFLRELPQPL 626
           Q+LR                  ++ G +   DL    +  DIH V    KL+ RELP PL
Sbjct: 65  QRLR------------------QEFGSDQCPDLTREVYLQDIHCVGSLCKLYFRELPNPL 106

Query: 627 VPPLLLPHFRAAL 639
           +   L   F  A+
Sbjct: 107 LTYELYEKFTEAV 119


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,245,048
Number of Sequences: 37866
Number of extensions: 1781119
Number of successful extensions: 8854
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 116
Number of HSP's successfully gapped in prelim test: 341
Number of HSP's that attempted gapping in prelim test: 8163
Number of HSP's gapped (non-prelim): 963
length of query: 640
length of database: 18,247,518
effective HSP length: 109
effective length of query: 531
effective length of database: 14,120,124
effective search space: 7497785844
effective search space used: 7497785844
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.