BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|122939151 Rho GTPase activating protein 9 isoform 2 [Homo sapiens] (640 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|122939151 Rho GTPase activating protein 9 isoform 2 [Homo sap... 1303 0.0 gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sap... 1301 0.0 gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sap... 928 0.0 gi|188497642 ARHGAP15 [Homo sapiens] 255 8e-68 gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] 239 4e-63 gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap... 236 4e-62 gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 235 1e-61 gi|23510413 sorting nexin 26 [Homo sapiens] 85 2e-16 gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] 80 4e-15 gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens] 79 2e-14 gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens] 74 3e-13 gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo sap... 68 2e-11 gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sap... 68 2e-11 gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens] 66 9e-11 gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens] 66 9e-11 gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sap... 65 1e-10 gi|229094128 active breakpoint cluster region-related protein i... 65 3e-10 gi|38679957 active breakpoint cluster region-related protein is... 65 3e-10 gi|38679954 active breakpoint cluster region-related protein is... 65 3e-10 gi|149274655 synapse defective 1, Rho GTPase, homolog 2 [Homo sa... 64 4e-10 gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 62 1e-09 gi|4757980 beta chimerin isoform 2 [Homo sapiens] 62 2e-09 gi|91106928 beta chimerin isoform 1 [Homo sapiens] 62 2e-09 gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens] 61 3e-09 gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] 61 4e-09 gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens] 58 3e-08 gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo sapi... 58 3e-08 gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo sapi... 58 3e-08 gi|5803145 ralA binding protein 1 [Homo sapiens] 57 7e-08 gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens] 57 7e-08 >gi|122939151 Rho GTPase activating protein 9 isoform 2 [Homo sapiens] Length = 640 Score = 1303 bits (3373), Expect = 0.0 Identities = 640/640 (100%), Positives = 640/640 (100%) Query: 1 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD 60 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD Sbjct: 1 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD 60 Query: 61 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA 120 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA Sbjct: 61 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA 120 Query: 121 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG 180 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG Sbjct: 121 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG 180 Query: 181 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK 240 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK Sbjct: 181 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK 240 Query: 241 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS 300 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS Sbjct: 241 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS 300 Query: 301 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY 360 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY Sbjct: 301 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY 360 Query: 361 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE 420 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE Sbjct: 361 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE 420 Query: 421 TELRAWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRS 480 TELRAWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRS Sbjct: 421 TELRAWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRS 480 Query: 481 SIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL 540 SIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL Sbjct: 481 SIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL 540 Query: 541 RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL 600 RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL Sbjct: 541 RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL 600 Query: 601 DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALG 640 DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALG Sbjct: 601 DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALG 640 >gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sapiens] Length = 731 Score = 1301 bits (3367), Expect = 0.0 Identities = 639/639 (100%), Positives = 639/639 (100%) Query: 1 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD 60 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD Sbjct: 1 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD 60 Query: 61 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA 120 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA Sbjct: 61 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA 120 Query: 121 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG 180 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG Sbjct: 121 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG 180 Query: 181 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK 240 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK Sbjct: 181 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK 240 Query: 241 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS 300 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS Sbjct: 241 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS 300 Query: 301 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY 360 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY Sbjct: 301 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY 360 Query: 361 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE 420 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE Sbjct: 361 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE 420 Query: 421 TELRAWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRS 480 TELRAWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRS Sbjct: 421 TELRAWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRS 480 Query: 481 SIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL 540 SIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL Sbjct: 481 SIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL 540 Query: 541 RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL 600 RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL Sbjct: 541 RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL 600 Query: 601 DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 639 DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL Sbjct: 601 DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 639 >gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sapiens] Length = 547 Score = 928 bits (2398), Expect = 0.0 Identities = 455/455 (100%), Positives = 455/455 (100%) Query: 185 MSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKP 244 MSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKP Sbjct: 1 MSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKP 60 Query: 245 PRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTSQLDP 304 PRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTSQLDP Sbjct: 61 PRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTSQLDP 120 Query: 305 PALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFYREPP 364 PALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFYREPP Sbjct: 121 PALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFYREPP 180 Query: 365 PTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHETELR 424 PTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHETELR Sbjct: 181 PTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHETELR 240 Query: 425 AWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRG 484 AWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRG Sbjct: 241 AWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRG 300 Query: 485 PEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCI 544 PEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCI Sbjct: 301 PEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCI 360 Query: 545 AAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTE 604 AAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTE Sbjct: 361 AAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTE 420 Query: 605 WDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 639 WDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL Sbjct: 421 WDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 455 >gi|188497642 ARHGAP15 [Homo sapiens] Length = 475 Score = 255 bits (652), Expect = 8e-68 Identities = 149/337 (44%), Positives = 208/337 (61%), Gaps = 40/337 (11%) Query: 312 PLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSG 371 PL QL+ VEK G L KIA GG+KLRKNW SW+VL+ + FY+E A S+ Sbjct: 74 PLEQLM-----VEKEGYLQKAKIADGGKKLRKNWSTSWIVLSSRRIEFYKESKQQALSNM 128 Query: 372 WGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALR 431 G +PES VDL GA + + SSR+NV I T+ G+EFLLQSD + + W A++ Sbjct: 129 --KTGHKPES-VDLCGAHIEWAKEKSSRKNVFQITTVSGNEFLLQSDIDFIILDWFHAIK 185 Query: 432 TVIERLDRENP-----LEL-RLSGSGPAELSAGED---EEEESELVSKPLLRLSSRRSSI 482 I+RL +++ LEL ++ S EL + D +E++ E + RL S Sbjct: 186 NAIDRLPKDSSCPSRNLELFKIQRSSSTELLSHYDSDIKEQKPEHRKSLMFRLHHSAS-- 243 Query: 483 RGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRL 542 + +++NRV+++LK+ I +RP L++LQE+GL++DQ+FG L +C+RE TVP F++ Sbjct: 244 ---DTSDKNRVKSRLKKFITRRPSLKTLQEKGLIKDQIFGSHLHKVCERENSTVPWFVKQ 300 Query: 543 CIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDS 602 CI AV+KRGLDVDGIYRVSGNLA +QKLRF+V+ QE +L+LD Sbjct: 301 CIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVN------------------QEEKLNLDD 342 Query: 603 TEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 639 ++W+DIHVVTGALK+F RELP+PL P F A+ Sbjct: 343 SQWEDIHVVTGALKMFFRELPEPLFPYSFFEQFVEAI 379 >gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] Length = 846 Score = 239 bits (611), Expect = 4e-63 Identities = 150/416 (36%), Positives = 237/416 (56%), Gaps = 42/416 (10%) Query: 217 DAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKG 276 + W +H+D + GR +Y ++ W+ P+ + S + +++L R K Sbjct: 362 EKWLKHVD-DQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTK- 419 Query: 277 FRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLD---DPHEVEKSGLLNMTK 333 +R T + D + S S+ P ++ P+ D P + EK GLLN+TK Sbjct: 420 WRHSTIVLDTNDKE-----SPTASKPCFPENESSPSSPKHQDTASSPKDQEKYGLLNVTK 474 Query: 334 IAQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHG 393 IA+ G+K+RKNW SW VL G+SL+F + + +S +G S+PE +VDL+GA + Sbjct: 475 IAENGKKVRKNWLSSWAVLQGSSLLFTKTQGSS--TSWFGSNQSKPEFTVDLKGATIEMA 532 Query: 394 -RHLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVI--ERLDRENPLELRLSGS 450 + SS++NV ++T G E L+QSD++T + W + L + I + ++ + +E + S Sbjct: 533 SKDKSSKKNVFELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQAVETDEGIEEEIPDS 592 Query: 451 GPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSL 510 E E E+++ P S + SSI + +EQ + + LK+ + +RP LQ++ Sbjct: 593 PGIEKHDKEKEQKD------PKKLRSFKVSSI---DSSEQKKTKKNLKKFLTRRPTLQAV 643 Query: 511 QERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKL 570 +E+G ++DQVFG L +LCQRE TVP F++LCI V++ GLD+DGIYRVSGNLAV+QKL Sbjct: 644 REKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKL 703 Query: 571 RFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPL 626 RF V+ + +LDL+ ++W+DIHV+TGALK+F RELP+PL Sbjct: 704 RFAVNHDE------------------KLDLNDSKWEDIHVITGALKMFFRELPEPL 741 Score = 66.2 bits (160), Expect = 9e-11 Identities = 42/122 (34%), Positives = 58/122 (47%), Gaps = 10/122 (8%) Query: 144 STDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRS 203 S D+ + Q+ SG LS +E +T P + PVY NL +L+ + Sbjct: 198 SCDSAGEGSERIHQDSESGDELSSSS--TEQIRATTPPNQGRPDSPVYANLQELKISQSA 255 Query: 204 PPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSET-------NPGS 256 PP P P +Q WE H D +SGRC+Y N T ++WKPPR +R + NPG Sbjct: 256 LPPLPGSPAIQINGEWETHKD-SSGRCYYYNRGTQERTWKPPRWTRDASISKGDFQNPGD 314 Query: 257 ME 258 E Sbjct: 315 QE 316 Score = 43.1 bits (100), Expect = 8e-04 Identities = 18/55 (32%), Positives = 35/55 (63%), Gaps = 4/55 (7%) Query: 31 YAFTYTGADGQQVSLAEGDRFLLLRKTNSDWWLARRLEAPSTSRPIFVPAAYMIE 85 Y + Y D +++ + +G+R++L++KTN DWW +++ S+ +VPA Y+ E Sbjct: 21 YDYEYEAKD-RKIVIKQGERYILVKKTNDDWW---QVKPDENSKAFYVPAQYVKE 71 >gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sapiens] Length = 548 Score = 236 bits (603), Expect = 4e-62 Identities = 161/456 (35%), Positives = 235/456 (51%), Gaps = 75/456 (16%) Query: 201 PRSPPPGPACPLLQ----------RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRS 250 P + PPG +C + Q + W + DP+ G+ ++ N W+ P+ Sbjct: 48 PLTTPPGWSCHVSQDKQMLYTNHFTQEQWVRLEDPH-GKPYFYNPEDSSVRWELPQVP-- 104 Query: 251 ETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAP 310 + +++ +++ A+ + P LD GS PA A Sbjct: 105 ------VPAPRSIHKSSQDGDTPAQASPPEEKVPAELDEVGSWEEVS-------PATAAV 151 Query: 311 RPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRK-NWGPSWVVLTGNSLVFYREPPPTAPS 369 R ++K+G+L+ TK A G++LRK +W SW VL G L F+++ +A Sbjct: 152 RT--------KTLDKAGVLHRTKTADKGKRLRKKHWSASWTVLEGGVLTFFKDSKTSAAG 203 Query: 370 SGWGPAG-SRPESSVDLRGAALAHG-RHLSSRRNVLHIRTIPGHEFLLQSDHETELRAWH 427 P+ S PE +V+LRGA L+ + SSR+NVL +R+ G E+L+Q D E + WH Sbjct: 204 GLRQPSKFSTPEYTVELRGATLSWAPKDKSSRKNVLELRSRDGSEYLIQHDSEAIISTWH 263 Query: 428 RALRTVIERLDRENPLELRLS-----GSGPAELSAGEDEEEESELVSKPLLRLSSRRSSI 482 +A+ I+ L E P E S GS S E EE+ + P L Sbjct: 264 KAIAQGIQELSAELPPEESESSRVDFGSSERLGSWQEKEEDARPNAAAPAL--------- 314 Query: 483 RGPEGTEQN--RVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL 540 GP G E + +VR+KL++ + +RP LQSL+E+G ++DQVFGC L +LC+RE VP F+ Sbjct: 315 -GPVGLESDLSKVRHKLRKFLQRRPTLQSLREKGYIKDQVFGCALAALCERERSRVPRFV 373 Query: 541 RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL 600 + CI AV+ RGLD+DG+YR+SGNLA +QKLR+ VD + RLDL Sbjct: 374 QQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHDE------------------RLDL 415 Query: 601 DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFR 636 D W+D+HV+TGALKLF RELP+PL P HFR Sbjct: 416 DDGRWEDVHVITGALKLFFRELPEPLFP---FSHFR 448 >gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sapiens] Length = 521 Score = 235 bits (599), Expect = 1e-61 Identities = 138/324 (42%), Positives = 192/324 (59%), Gaps = 41/324 (12%) Query: 323 VEKSGLLNMTKIAQGGRKLRK-NWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAG-SRPE 380 ++K+G+L+ TK A G++LRK +W SW VL G L F+++ +A P+ S PE Sbjct: 129 LDKAGVLHRTKTADKGKRLRKKHWSASWTVLEGGVLTFFKDSKTSAAGGLRQPSKFSTPE 188 Query: 381 SSVDLRGAALAHG-RHLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLDR 439 +V+LRGA L+ + SSR+NVL +R+ G E+L+Q D E + WH+A+ I+ L Sbjct: 189 YTVELRGATLSWAPKDKSSRKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAQGIQELSA 248 Query: 440 ENPLELRLS-----GSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQN--R 492 E P E S GS S E EE+ + P L GP G E + + Sbjct: 249 ELPPEESESSRVDFGSSERLGSWQEKEEDARPNAAAPAL----------GPVGLESDLSK 298 Query: 493 VRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGL 552 VR+KL++ + +RP LQSL+E+G ++DQVFGC L +LC+RE VP F++ CI AV+ RGL Sbjct: 299 VRHKLRKFLQRRPTLQSLREKGYIKDQVFGCALAALCERERSRVPRFVQQCIRAVEARGL 358 Query: 553 DVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVT 612 D+DG+YR+SGNLA +QKLR+ VD + RLDLD W+D+HV+T Sbjct: 359 DIDGLYRISGNLATIQKLRYKVDHDE------------------RLDLDDGRWEDVHVIT 400 Query: 613 GALKLFLRELPQPLVPPLLLPHFR 636 GALKLF RELP+PL P HFR Sbjct: 401 GALKLFFRELPEPLFP---FSHFR 421 >gi|23510413 sorting nexin 26 [Homo sapiens] Length = 1126 Score = 85.1 bits (209), Expect = 2e-16 Identities = 58/165 (35%), Positives = 80/165 (48%), Gaps = 22/165 (13%) Query: 475 LSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGD 534 +SS S++ P G ++ L+ + RP Q L++RG+LR +VFGC L G Sbjct: 271 ISSLTSAVPRPRG----KLAGLLRTFMRSRPSRQRLRQRGILRQRVFGCDLGEHLSNSGQ 326 Query: 535 TVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQ 594 VP LR C ++ G+ VDGIYR+SG + +Q+LR D ER PE G Sbjct: 327 DVPQVLRCCSEFIEAHGV-VDGIYRLSGVSSNIQRLRHEFDSER---------IPELSG- 375 Query: 595 EGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 639 DIH V+ KL+ RELP PL+ L F A+ Sbjct: 376 -------PAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSEAM 413 >gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] Length = 1397 Score = 80.5 bits (197), Expect = 4e-15 Identities = 80/301 (26%), Positives = 130/301 (43%), Gaps = 38/301 (12%) Query: 343 KNWGPSWVVLTGNSLVFY---REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSR 399 + W + L SL REP P A + AG + V + + + R Sbjct: 619 RQWKRVYAALRARSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKR 678 Query: 400 RNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLDRENP-------LELRLSGSGP 452 R+V + T E+L Q++ ++ W RA+R R + E+P + +L+ Sbjct: 679 RHVFRLTTADFCEYLFQAEDRDDMLGWIRAIREN-SRAEGEDPGCANQALISKKLNDYRK 737 Query: 453 AELSAGEDEEEESELVSKPLLRLSS---RRSSIRGPEGTEQNRVRNKLKRLIAKRPP--L 507 S+G + + S S+ L L S ++S+ RG T+ +K A + P + Sbjct: 738 VSHSSGP-KADSSPKGSRGLGGLKSEFLKQSAARGLR-TQDLPAGSKDDSAAAPKTPWGI 795 Query: 508 QSLQERGLLRDQVFGCQLESLCQ--REGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLA 565 +++ + FG +LE CQ E VP + C V+ RGL+ GIYRV GN A Sbjct: 796 NIIKKNKKAAPRAFGVRLEE-CQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNA 854 Query: 566 VVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQP 625 VV L+ ++R G ++L W D++V++ LK F R+LP+P Sbjct: 855 VVSSLQEQLNR-----------------GPGDINLQDERWQDLNVISSLLKSFFRKLPEP 897 Query: 626 L 626 L Sbjct: 898 L 898 >gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens] Length = 2087 Score = 78.6 bits (192), Expect = 2e-14 Identities = 52/161 (32%), Positives = 78/161 (48%), Gaps = 20/161 (12%) Query: 480 SSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSF 539 +S+ P + ++ L+ + RP Q L++RG+L+++VFGC L G VP Sbjct: 329 NSVPKPVSKKHGKLITFLRTFMKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQV 388 Query: 540 LRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLD 599 L+ C A +++ G+ VDGIYR+SG + +Q+LR D E D Sbjct: 389 LQSCTAFIERYGI-VDGIYRLSGVASNIQRLRHEFDSEHVP------------------D 429 Query: 600 LDSTEW-DDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 639 L + DIH V KL+ RELP PL+ L F A+ Sbjct: 430 LTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAV 470 >gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens] Length = 1738 Score = 74.3 bits (181), Expect = 3e-13 Identities = 49/137 (35%), Positives = 68/137 (49%), Gaps = 20/137 (14%) Query: 504 RPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGN 563 RP Q L++RG+L+++VFGC L G VP L+ C A +++ G+ VDGIYR+SG Sbjct: 4 RPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGI-VDGIYRLSGV 62 Query: 564 LAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEW-DDIHVVTGALKLFLREL 622 + +Q+LR D E DL + DIH V KL+ REL Sbjct: 63 ASNIQRLRHEFDSEHVP------------------DLTKEPYVQDIHSVGSLCKLYFREL 104 Query: 623 PQPLVPPLLLPHFRAAL 639 P PL+ L F A+ Sbjct: 105 PNPLLTYQLYEKFSDAV 121 >gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo sapiens] Length = 890 Score = 68.2 bits (165), Expect = 2e-11 Identities = 46/133 (34%), Positives = 67/133 (50%), Gaps = 18/133 (13%) Query: 508 QSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVV 567 Q +++G +++VFGC L+ Q G VP L+ C V++ G+ VDGIYR+SG + + Sbjct: 5 QKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGV-VDGIYRLSGVSSNI 63 Query: 568 QKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLV 627 QKLR + ER +P + L DIH V+ K + RELP PL+ Sbjct: 64 QKLRQEFESER------------KPDLRRDVYL-----QDIHCVSSLCKAYFRELPDPLL 106 Query: 628 PPLLLPHFRAALG 640 L F A+G Sbjct: 107 TYRLYDKFAEAVG 119 >gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sapiens] Length = 1101 Score = 68.2 bits (165), Expect = 2e-11 Identities = 46/133 (34%), Positives = 67/133 (50%), Gaps = 18/133 (13%) Query: 508 QSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVV 567 Q +++G +++VFGC L+ Q G VP L+ C V++ G+ VDGIYR+SG + + Sbjct: 5 QKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGV-VDGIYRLSGVSSNI 63 Query: 568 QKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLV 627 QKLR + ER +P + L DIH V+ K + RELP PL+ Sbjct: 64 QKLRQEFESER------------KPDLRRDVYL-----QDIHCVSSLCKAYFRELPDPLL 106 Query: 628 PPLLLPHFRAALG 640 L F A+G Sbjct: 107 TYRLYDKFAEAVG 119 >gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens] Length = 459 Score = 66.2 bits (160), Expect = 9e-11 Identities = 36/117 (30%), Positives = 62/117 (52%), Gaps = 17/117 (14%) Query: 519 QVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRER 578 +V+ C L +L + P + +CI ++ RGL+ +G+YRVSG +++ ++ DR Sbjct: 264 KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDR-- 321 Query: 579 AVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHF 635 DG + D+ ++DI+++TGALKL+ R+LP PL+ P F Sbjct: 322 ----DGE-----------KADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKF 363 >gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens] Length = 433 Score = 66.2 bits (160), Expect = 9e-11 Identities = 36/117 (30%), Positives = 62/117 (52%), Gaps = 17/117 (14%) Query: 519 QVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRER 578 +V+ C L +L + P + +CI ++ RGL+ +G+YRVSG +++ ++ DR Sbjct: 238 KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDR-- 295 Query: 579 AVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHF 635 DG + D+ ++DI+++TGALKL+ R+LP PL+ P F Sbjct: 296 ----DGE-----------KADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKF 337 >gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sapiens] Length = 735 Score = 65.5 bits (158), Expect = 1e-10 Identities = 46/142 (32%), Positives = 73/142 (51%), Gaps = 20/142 (14%) Query: 489 EQNRVRNKLKRLIAKRPPLQSLQERGLLRD-QVFGCQLESLCQREGDT--VPSFLRLCIA 545 +Q VR + + L+ + L QE + +VFG L L +RE VP ++ C+ Sbjct: 363 QQLAVRLEPQGLLYAKLTLSEQQEAPATAEPRVFGLPLPLLVERERPPGQVPLIIQKCVG 422 Query: 546 AVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEW 605 +++RGL V G+YR+ G+ AV ++LR +R+ A ++P Sbjct: 423 QIERRGLRVVGLYRLCGSAAVKKELRDAFERDSAAVCLSEDLYP---------------- 466 Query: 606 DDIHVVTGALKLFLRELPQPLV 627 DI+V+TG LK +LRELP PL+ Sbjct: 467 -DINVITGILKDYLRELPTPLI 487 >gi|229094128 active breakpoint cluster region-related protein isoform c [Homo sapiens] Length = 813 Score = 64.7 bits (156), Expect = 3e-10 Identities = 39/116 (33%), Positives = 59/116 (50%), Gaps = 18/116 (15%) Query: 520 VFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERA 579 VFG ++ + +RE VP +R C+ V+KRG++ GIYR+SG +Q L+ + D A Sbjct: 598 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFD---A 654 Query: 580 VTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHF 635 D + + DI+ + G LKL+ RELP+PL+ L P F Sbjct: 655 NNKDILLMLSDM---------------DINAIAGTLKLYFRELPEPLLTDRLYPAF 695 >gi|38679957 active breakpoint cluster region-related protein isoform a [Homo sapiens] Length = 859 Score = 64.7 bits (156), Expect = 3e-10 Identities = 39/116 (33%), Positives = 59/116 (50%), Gaps = 18/116 (15%) Query: 520 VFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERA 579 VFG ++ + +RE VP +R C+ V+KRG++ GIYR+SG +Q L+ + D A Sbjct: 644 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFD---A 700 Query: 580 VTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHF 635 D + + DI+ + G LKL+ RELP+PL+ L P F Sbjct: 701 NNKDILLMLSDM---------------DINAIAGTLKLYFRELPEPLLTDRLYPAF 741 >gi|38679954 active breakpoint cluster region-related protein isoform b [Homo sapiens] Length = 822 Score = 64.7 bits (156), Expect = 3e-10 Identities = 39/116 (33%), Positives = 59/116 (50%), Gaps = 18/116 (15%) Query: 520 VFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERA 579 VFG ++ + +RE VP +R C+ V+KRG++ GIYR+SG +Q L+ + D A Sbjct: 607 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFD---A 663 Query: 580 VTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHF 635 D + + DI+ + G LKL+ RELP+PL+ L P F Sbjct: 664 NNKDILLMLSDM---------------DINAIAGTLKLYFRELPEPLLTDRLYPAF 704 >gi|149274655 synapse defective 1, Rho GTPase, homolog 2 [Homo sapiens] Length = 1194 Score = 63.9 bits (154), Expect = 4e-10 Identities = 36/110 (32%), Positives = 60/110 (54%), Gaps = 19/110 (17%) Query: 520 VFGCQLESLCQRE--GDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRE 577 +FG ++ + ++E G VP ++ CI ++KRG V G+YR+ G+ AV ++LR +R+ Sbjct: 813 IFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFERD 872 Query: 578 RAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLV 627 + L ++ DI+V+TG LK +LRELP PL+ Sbjct: 873 SKA-----------------VGLCENQYPDINVITGVLKDYLRELPSPLI 905 >gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] Length = 1958 Score = 62.4 bits (150), Expect = 1e-09 Identities = 65/310 (20%), Positives = 126/310 (40%), Gaps = 61/310 (19%) Query: 345 WGPSWVVLTGNSLVFYREP-PPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVL 403 W +VVL G+SL Y++ T PS E + + + + R+NV Sbjct: 958 WKQMYVVLRGHSLYLYKDKREQTTPSE--------EEQPISVNACLIDISYSETKRKNVF 1009 Query: 404 HIRTIPGHEFLLQSDHETELRAWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEE- 462 + T E L Q++ ++ AW I+ + + L +G +L + +E Sbjct: 1010 RLTT-SDCECLFQAEDRDDMLAW-------IKTIQESSNLNEEDTGVTNRDLISRRIKEY 1061 Query: 463 -----EESELVSKPLLRLSSRRSSIRG---PEGTEQNRVRNKLKRLIAKRPPLQSLQERG 514 + +L P LS R++ + P+ + + + +R + + +++G Sbjct: 1062 NNLMSKAEQLPKTPRQSLSIRQTLLGAKSEPKTQSPHSPKEESERKLLSKDDTSPPKDKG 1121 Query: 515 LLRDQV-----------------FGCQLESLCQREGDT-VPSFLRLCIAAVDKRGLDVDG 556 R + FG +L+ + +P + +C V++RGL+ G Sbjct: 1122 TWRKGIPSIMRKTFEKKPTATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTG 1181 Query: 557 IYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALK 616 IYRV GN A + ++ +++ A +D+ +W D++V++ LK Sbjct: 1182 IYRVPGNNAAISSMQEELNKGMA-----------------DIDIQDDKWRDLNVISSLLK 1224 Query: 617 LFLRELPQPL 626 F R+LP+PL Sbjct: 1225 SFFRKLPEPL 1234 >gi|4757980 beta chimerin isoform 2 [Homo sapiens] Length = 468 Score = 62.0 bits (149), Expect = 2e-09 Identities = 33/109 (30%), Positives = 58/109 (53%), Gaps = 17/109 (15%) Query: 519 QVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRER 578 +V+ C L +L + P + +CI ++ RGL +G+YRVSG ++ ++ DR Sbjct: 273 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR-- 330 Query: 579 AVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLV 627 DG + D+ + + DI+++TGALKL+ R+LP P++ Sbjct: 331 ----DGE-----------KADISANVYPDINIITGALKLYFRDLPIPVI 364 >gi|91106928 beta chimerin isoform 1 [Homo sapiens] Length = 332 Score = 62.0 bits (149), Expect = 2e-09 Identities = 33/109 (30%), Positives = 58/109 (53%), Gaps = 17/109 (15%) Query: 519 QVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRER 578 +V+ C L +L + P + +CI ++ RGL +G+YRVSG ++ ++ DR Sbjct: 137 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR-- 194 Query: 579 AVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLV 627 DG + D+ + + DI+++TGALKL+ R+LP P++ Sbjct: 195 ----DGE-----------KADISANVYPDINIITGALKLYFRDLPIPVI 228 >gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens] Length = 1271 Score = 61.2 bits (147), Expect = 3e-09 Identities = 49/180 (27%), Positives = 81/180 (45%), Gaps = 23/180 (12%) Query: 459 EDEEEESELVSKPLLRLSSRRSSIRGPEGT--EQNRVRNKLK-RLIAKRPPLQSLQERGL 515 ED E L+ K ++L + R + T N + KL + ++ L+ + R Sbjct: 989 EDGESTDRLMGKGQVQLDPQALQDRDWQRTVIAMNGIEVKLSVKFNSREFSLKRMPSRK- 1047 Query: 516 LRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVD 575 + VFG ++ + +RE VP +R C+ +++RG++ GIYRVSG +Q L+ D Sbjct: 1048 -QTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFD 1106 Query: 576 RERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHF 635 D + E D++ + G LKL+ RELP+PL P+F Sbjct: 1107 ---VNNKDVSVMMSEM---------------DVNAIAGTLKLYFRELPEPLFTDEFYPNF 1148 >gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] Length = 1227 Score = 60.8 bits (146), Expect = 4e-09 Identities = 36/116 (31%), Positives = 56/116 (48%), Gaps = 18/116 (15%) Query: 520 VFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERA 579 VFG ++ + +RE VP +R C+ +++RG++ GIYRVSG +Q L+ D Sbjct: 1007 VFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFD---V 1063 Query: 580 VTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHF 635 D + E D++ + G LKL+ RELP+PL P+F Sbjct: 1064 NNKDVSVMMSEM---------------DVNAIAGTLKLYFRELPEPLFTDEFYPNF 1104 >gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens] Length = 555 Score = 57.8 bits (138), Expect = 3e-08 Identities = 41/139 (29%), Positives = 69/139 (49%), Gaps = 23/139 (16%) Query: 492 RVRNKLKRLIAKR--PPLQSLQERGLLRDQVFGCQLESLCQR-EGDTVPSFLRLCIAAVD 548 R KL+ L R PP ++ R L Q FG L+ L + +G+ +P LR + + Sbjct: 284 RYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLR 343 Query: 549 KRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDI 608 ++GL +G++R S ++ V++++ L ++ + V D ++ DI Sbjct: 344 EKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFD--------------------DYGDI 383 Query: 609 HVVTGALKLFLRELPQPLV 627 H+ LK FLRELPQPL+ Sbjct: 384 HIPAVILKTFLRELPQPLL 402 >gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo sapiens] Length = 433 Score = 57.8 bits (138), Expect = 3e-08 Identities = 41/139 (29%), Positives = 69/139 (49%), Gaps = 23/139 (16%) Query: 492 RVRNKLKRLIAKR--PPLQSLQERGLLRDQVFGCQLESLCQR-EGDTVPSFLRLCIAAVD 548 R KL+ L R PP ++ R L Q FG L+ L + +G+ +P LR + + Sbjct: 162 RYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLR 221 Query: 549 KRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDI 608 ++GL +G++R S ++ V++++ L ++ + V D ++ DI Sbjct: 222 EKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFD--------------------DYGDI 261 Query: 609 HVVTGALKLFLRELPQPLV 627 H+ LK FLRELPQPL+ Sbjct: 262 HIPAVILKTFLRELPQPLL 280 >gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo sapiens] Length = 464 Score = 57.8 bits (138), Expect = 3e-08 Identities = 41/139 (29%), Positives = 69/139 (49%), Gaps = 23/139 (16%) Query: 492 RVRNKLKRLIAKR--PPLQSLQERGLLRDQVFGCQLESLCQR-EGDTVPSFLRLCIAAVD 548 R KL+ L R PP ++ R L Q FG L+ L + +G+ +P LR + + Sbjct: 193 RYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLR 252 Query: 549 KRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDI 608 ++GL +G++R S ++ V++++ L ++ + V D ++ DI Sbjct: 253 EKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFD--------------------DYGDI 292 Query: 609 HVVTGALKLFLRELPQPLV 627 H+ LK FLRELPQPL+ Sbjct: 293 HIPAVILKTFLRELPQPLL 311 >gi|5803145 ralA binding protein 1 [Homo sapiens] Length = 655 Score = 56.6 bits (135), Expect = 7e-08 Identities = 50/186 (26%), Positives = 80/186 (43%), Gaps = 32/186 (17%) Query: 461 EEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQV 520 EE+ E K + + + +Q + + K K+ I + P + + L + Sbjct: 133 EEKHKEEKHKEEKHKEKKSKDLTAADVVKQWKEKKKKKKPI-QEPEVPQIDVPNL--KPI 189 Query: 521 FGCQLESLCQR----EGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDR 576 FG L +R +G +P+ R CI V+K G+ +GIYRVSG + V +L+ DR Sbjct: 190 FGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAYDR 249 Query: 577 ERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDI--HVVTGALKLFLRELPQPLVPPLLLPH 634 E +ST +D + V LK +LR+LP+ L+ L+P Sbjct: 250 E-----------------------ESTNLEDYEPNTVASLLKQYLRDLPENLLTKELMPR 286 Query: 635 FRAALG 640 F A G Sbjct: 287 FEEACG 292 >gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens] Length = 1444 Score = 56.6 bits (135), Expect = 7e-08 Identities = 42/133 (31%), Positives = 60/133 (45%), Gaps = 22/133 (16%) Query: 508 QSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVV 567 Q L+ +G FGC L + G VP L+ C ++ G+ VDGIYR+SG + + Sbjct: 8 QKLKRKGAA--SAFGCDLTEYLESSGQDVPYVLKSCAEFIETHGI-VDGIYRLSGVTSNI 64 Query: 568 QKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEW-DDIHVVTGALKLFLRELPQPL 626 Q+LR ++ G + DL + DIH V KL+ RELP PL Sbjct: 65 QRLR------------------QEFGSDQCPDLTREVYLQDIHCVGSLCKLYFRELPNPL 106 Query: 627 VPPLLLPHFRAAL 639 + L F A+ Sbjct: 107 LTYELYEKFTEAV 119 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.134 0.412 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,245,048 Number of Sequences: 37866 Number of extensions: 1781119 Number of successful extensions: 8854 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 116 Number of HSP's successfully gapped in prelim test: 341 Number of HSP's that attempted gapping in prelim test: 8163 Number of HSP's gapped (non-prelim): 963 length of query: 640 length of database: 18,247,518 effective HSP length: 109 effective length of query: 531 effective length of database: 14,120,124 effective search space: 7497785844 effective search space used: 7497785844 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.