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Search of human proteins with 32528293
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32528293 ecto-NOX disulfide-thiol exchanger 2 isoform a
[Homo sapiens]
(581 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32528293 ecto-NOX disulfide-thiol exchanger 2 isoform a [Homo... 1181 0.0
gi|32528291 ecto-NOX disulfide-thiol exchanger 2 isoform b [Homo... 1181 0.0
gi|189027048 ecto-NOX disulfide-thiol exchanger 1 [Homo sapiens] 826 0.0
gi|189027046 ecto-NOX disulfide-thiol exchanger 1 [Homo sapiens] 826 0.0
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 69 9e-12
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 69 2e-11
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 64 4e-10
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 63 8e-10
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 61 3e-09
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 60 7e-09
gi|21735548 centrosomal protein 2 [Homo sapiens] 59 1e-08
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 58 3e-08
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 58 3e-08
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 57 4e-08
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 57 5e-08
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 56 8e-08
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 56 8e-08
gi|55770834 centromere protein F [Homo sapiens] 55 1e-07
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 55 2e-07
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 54 3e-07
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 54 5e-07
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 54 5e-07
gi|9910266 kinesin family member 15 [Homo sapiens] 53 9e-07
gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-l... 52 1e-06
gi|113425137 PREDICTED: similar to Golgin subfamily A member 8-l... 52 1e-06
gi|148746195 trichohyalin [Homo sapiens] 52 1e-06
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 52 1e-06
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 52 1e-06
gi|221219020 NYD-SP11 protein [Homo sapiens] 52 1e-06
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 52 1e-06
>gi|32528293 ecto-NOX disulfide-thiol exchanger 2 isoform a [Homo
sapiens]
Length = 581
Score = 1181 bits (3054), Expect = 0.0
Identities = 581/581 (100%), Positives = 581/581 (100%)
Query: 1 MTLPMSDPTAWATAMNNLGMAPLGIAGQPILPDFDPALGMMTGIPPITPMMPGLGIVPPP 60
MTLPMSDPTAWATAMNNLGMAPLGIAGQPILPDFDPALGMMTGIPPITPMMPGLGIVPPP
Sbjct: 1 MTLPMSDPTAWATAMNNLGMAPLGIAGQPILPDFDPALGMMTGIPPITPMMPGLGIVPPP 60
Query: 61 IPPDMPVVKEIIHCKSCTLFPPNPNLPPPATRERPPGCKTVFVGGLPENGTEQIIVEVFE 120
IPPDMPVVKEIIHCKSCTLFPPNPNLPPPATRERPPGCKTVFVGGLPENGTEQIIVEVFE
Sbjct: 61 IPPDMPVVKEIIHCKSCTLFPPNPNLPPPATRERPPGCKTVFVGGLPENGTEQIIVEVFE 120
Query: 121 QCGEIIAIRKSKKNFCHIRFAEEYMVDKALYLSGYRIRLGSSTDKKDTGRLHVDFAQARD 180
QCGEIIAIRKSKKNFCHIRFAEEYMVDKALYLSGYRIRLGSSTDKKDTGRLHVDFAQARD
Sbjct: 121 QCGEIIAIRKSKKNFCHIRFAEEYMVDKALYLSGYRIRLGSSTDKKDTGRLHVDFAQARD 180
Query: 181 DLYEWECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSEAV 240
DLYEWECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSEAV
Sbjct: 181 DLYEWECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSEAV 240
Query: 241 QTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGIL 300
QTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGIL
Sbjct: 241 QTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGIL 300
Query: 301 IQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMS 360
IQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMS
Sbjct: 301 IQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMS 360
Query: 361 DDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPN 420
DDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPN
Sbjct: 361 DDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPN 420
Query: 421 KEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKESCASRL 480
KEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKESCASRL
Sbjct: 421 KEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKESCASRL 480
Query: 481 CASNQDSEYPLEKTMNSSPIKSEREALLVGIISTFLHVHPFGASIEYICSYLHRLDNKIC 540
CASNQDSEYPLEKTMNSSPIKSEREALLVGIISTFLHVHPFGASIEYICSYLHRLDNKIC
Sbjct: 481 CASNQDSEYPLEKTMNSSPIKSEREALLVGIISTFLHVHPFGASIEYICSYLHRLDNKIC 540
Query: 541 TSDVECLMGRLQHTFKQEMTGVGASLEKRWKFCGFEGLKLT 581
TSDVECLMGRLQHTFKQEMTGVGASLEKRWKFCGFEGLKLT
Sbjct: 541 TSDVECLMGRLQHTFKQEMTGVGASLEKRWKFCGFEGLKLT 581
>gi|32528291 ecto-NOX disulfide-thiol exchanger 2 isoform b [Homo
sapiens]
Length = 610
Score = 1181 bits (3054), Expect = 0.0
Identities = 581/581 (100%), Positives = 581/581 (100%)
Query: 1 MTLPMSDPTAWATAMNNLGMAPLGIAGQPILPDFDPALGMMTGIPPITPMMPGLGIVPPP 60
MTLPMSDPTAWATAMNNLGMAPLGIAGQPILPDFDPALGMMTGIPPITPMMPGLGIVPPP
Sbjct: 30 MTLPMSDPTAWATAMNNLGMAPLGIAGQPILPDFDPALGMMTGIPPITPMMPGLGIVPPP 89
Query: 61 IPPDMPVVKEIIHCKSCTLFPPNPNLPPPATRERPPGCKTVFVGGLPENGTEQIIVEVFE 120
IPPDMPVVKEIIHCKSCTLFPPNPNLPPPATRERPPGCKTVFVGGLPENGTEQIIVEVFE
Sbjct: 90 IPPDMPVVKEIIHCKSCTLFPPNPNLPPPATRERPPGCKTVFVGGLPENGTEQIIVEVFE 149
Query: 121 QCGEIIAIRKSKKNFCHIRFAEEYMVDKALYLSGYRIRLGSSTDKKDTGRLHVDFAQARD 180
QCGEIIAIRKSKKNFCHIRFAEEYMVDKALYLSGYRIRLGSSTDKKDTGRLHVDFAQARD
Sbjct: 150 QCGEIIAIRKSKKNFCHIRFAEEYMVDKALYLSGYRIRLGSSTDKKDTGRLHVDFAQARD 209
Query: 181 DLYEWECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSEAV 240
DLYEWECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSEAV
Sbjct: 210 DLYEWECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSEAV 269
Query: 241 QTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGIL 300
QTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGIL
Sbjct: 270 QTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGIL 329
Query: 301 IQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMS 360
IQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMS
Sbjct: 330 IQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMS 389
Query: 361 DDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPN 420
DDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPN
Sbjct: 390 DDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPN 449
Query: 421 KEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKESCASRL 480
KEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKESCASRL
Sbjct: 450 KEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKESCASRL 509
Query: 481 CASNQDSEYPLEKTMNSSPIKSEREALLVGIISTFLHVHPFGASIEYICSYLHRLDNKIC 540
CASNQDSEYPLEKTMNSSPIKSEREALLVGIISTFLHVHPFGASIEYICSYLHRLDNKIC
Sbjct: 510 CASNQDSEYPLEKTMNSSPIKSEREALLVGIISTFLHVHPFGASIEYICSYLHRLDNKIC 569
Query: 541 TSDVECLMGRLQHTFKQEMTGVGASLEKRWKFCGFEGLKLT 581
TSDVECLMGRLQHTFKQEMTGVGASLEKRWKFCGFEGLKLT
Sbjct: 570 TSDVECLMGRLQHTFKQEMTGVGASLEKRWKFCGFEGLKLT 610
>gi|189027048 ecto-NOX disulfide-thiol exchanger 1 [Homo sapiens]
Length = 643
Score = 826 bits (2134), Expect = 0.0
Identities = 405/608 (66%), Positives = 494/608 (81%), Gaps = 29/608 (4%)
Query: 1 MTLPMSDPTAWATAMNNLGMAPLGIAGQPIL------PDFDPALGMMTGIPPITPMMPGL 54
+ + ++DPTAWATAMNNLGM P+G+ GQ ++ P FDP+L MMTGI PI PM+PGL
Sbjct: 38 LNMSVTDPTAWATAMNNLGMVPVGLPGQQLVSDSICVPGFDPSLNMMTGITPINPMIPGL 97
Query: 55 GIVPPPIPPDMPVVKEIIHCKSCTLFPPNPNLPPPATRERPPGCKTVFVGGLPENGTEQI 114
G+VPPP P ++ VVKEIIHCKSCTLFP NPNLPPP+TRERPPGCKTVFVGGLPEN TE+I
Sbjct: 98 GLVPPPPPTEVAVVKEIIHCKSCTLFPQNPNLPPPSTRERPPGCKTVFVGGLPENATEEI 157
Query: 115 IVEVFEQCGEIIAIRKSKKNFCHIRFAEEYMVDKALYLSGYRIRLGSSTDKKDTGRLHVD 174
I EVFEQCG+I AIRKSKKNFCHIRFAEE+MVDKA+YLSGYR+RLGSSTDKKD+GRLHVD
Sbjct: 158 IQEVFEQCGDITAIRKSKKNFCHIRFAEEFMVDKAIYLSGYRMRLGSSTDKKDSGRLHVD 217
Query: 175 FAQARDDLYEWECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDS 234
FAQARDD YEWECKQRM AREERHRR++EE+RLRPPSPP ++HYS+HE +++AEKLKDDS
Sbjct: 218 FAQARDDFYEWECKQRMRAREERHRRKLEEDRLRPPSPPAIMHYSEHEAALLAEKLKDDS 277
Query: 235 KFSEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQ 294
KFSEA+ LL+WIERGEVNRRSAN FYSM+QSANSHVRRL+NEKA HE++MEEAKE FK
Sbjct: 278 KFSEAITVLLSWIERGEVNRRSANQFYSMVQSANSHVRRLMNEKATHEQEMEEAKENFKN 337
Query: 295 ALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRRE 354
AL+GIL QFEQIVAV++++++QKAWDHF+KAQRKNI +W K +EE+RN +++LMGIRRE
Sbjct: 338 ALTGILTQFEQIVAVFNASTRQKAWDHFSKAQRKNIDIWRKHSEELRNAQSEQLMGIRRE 397
Query: 355 EEMEMSDDE-IEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKV 413
EEMEMSDDE + T+ +ESAL +QA ALKEENDSLRWQLDAYRNEVELLKQE+ ++
Sbjct: 398 EEMEMSDDENCDSPTKKMRVDESALAAQAYALKEENDSLRWQLDAYRNEVELLKQEKEQL 457
Query: 414 HR-EDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKE 472
R E++ K+QQL+ LQQ +QGMQQ LL +QEE K++ELE+ K+++ + +L+ L+E
Sbjct: 458 FRTEENLTKDQQLQFLQQTMQGMQQQLLTIQEELNNKKSELEQAKEEQSHTQALLKVLQE 517
Query: 473 KESCASRLCAS-------------------NQDSEYPLEKTMNSSPIKSEREALLVGIIS 513
+ L + NQD E +EK S +KSE+EALL+GIIS
Sbjct: 518 QLKGTKELVETNGHSHEDSNEINVLTVALVNQDRENNIEK--RSQGLKSEKEALLIGIIS 575
Query: 514 TFLHVHPFGASIEYICSYLHRLDNKICTSDVECLMGRLQHTFKQEMTGVGASLEKRWKFC 573
TFLHVHPFGA+IEY+ SY+ +LD+KI +++E L+ RL FKQE TGVGA+LEKRWK C
Sbjct: 576 TFLHVHPFGANIEYLWSYMQQLDSKISANEIEMLLMRLPRMFKQEFTGVGATLEKRWKLC 635
Query: 574 GFEGLKLT 581
FEG+K T
Sbjct: 636 AFEGIKTT 643
>gi|189027046 ecto-NOX disulfide-thiol exchanger 1 [Homo sapiens]
Length = 643
Score = 826 bits (2134), Expect = 0.0
Identities = 405/608 (66%), Positives = 494/608 (81%), Gaps = 29/608 (4%)
Query: 1 MTLPMSDPTAWATAMNNLGMAPLGIAGQPIL------PDFDPALGMMTGIPPITPMMPGL 54
+ + ++DPTAWATAMNNLGM P+G+ GQ ++ P FDP+L MMTGI PI PM+PGL
Sbjct: 38 LNMSVTDPTAWATAMNNLGMVPVGLPGQQLVSDSICVPGFDPSLNMMTGITPINPMIPGL 97
Query: 55 GIVPPPIPPDMPVVKEIIHCKSCTLFPPNPNLPPPATRERPPGCKTVFVGGLPENGTEQI 114
G+VPPP P ++ VVKEIIHCKSCTLFP NPNLPPP+TRERPPGCKTVFVGGLPEN TE+I
Sbjct: 98 GLVPPPPPTEVAVVKEIIHCKSCTLFPQNPNLPPPSTRERPPGCKTVFVGGLPENATEEI 157
Query: 115 IVEVFEQCGEIIAIRKSKKNFCHIRFAEEYMVDKALYLSGYRIRLGSSTDKKDTGRLHVD 174
I EVFEQCG+I AIRKSKKNFCHIRFAEE+MVDKA+YLSGYR+RLGSSTDKKD+GRLHVD
Sbjct: 158 IQEVFEQCGDITAIRKSKKNFCHIRFAEEFMVDKAIYLSGYRMRLGSSTDKKDSGRLHVD 217
Query: 175 FAQARDDLYEWECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDS 234
FAQARDD YEWECKQRM AREERHRR++EE+RLRPPSPP ++HYS+HE +++AEKLKDDS
Sbjct: 218 FAQARDDFYEWECKQRMRAREERHRRKLEEDRLRPPSPPAIMHYSEHEAALLAEKLKDDS 277
Query: 235 KFSEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQ 294
KFSEA+ LL+WIERGEVNRRSAN FYSM+QSANSHVRRL+NEKA HE++MEEAKE FK
Sbjct: 278 KFSEAITVLLSWIERGEVNRRSANQFYSMVQSANSHVRRLMNEKATHEQEMEEAKENFKN 337
Query: 295 ALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRRE 354
AL+GIL QFEQIVAV++++++QKAWDHF+KAQRKNI +W K +EE+RN +++LMGIRRE
Sbjct: 338 ALTGILTQFEQIVAVFNASTRQKAWDHFSKAQRKNIDIWRKHSEELRNAQSEQLMGIRRE 397
Query: 355 EEMEMSDDE-IEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKV 413
EEMEMSDDE + T+ +ESAL +QA ALKEENDSLRWQLDAYRNEVELLKQE+ ++
Sbjct: 398 EEMEMSDDENCDSPTKKMRVDESALAAQAYALKEENDSLRWQLDAYRNEVELLKQEKEQL 457
Query: 414 HR-EDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKE 472
R E++ K+QQL+ LQQ +QGMQQ LL +QEE K++ELE+ K+++ + +L+ L+E
Sbjct: 458 FRTEENLTKDQQLQFLQQTMQGMQQQLLTIQEELNNKKSELEQAKEEQSHTQALLKVLQE 517
Query: 473 KESCASRLCAS-------------------NQDSEYPLEKTMNSSPIKSEREALLVGIIS 513
+ L + NQD E +EK S +KSE+EALL+GIIS
Sbjct: 518 QLKGTKELVETNGHSHEDSNEINVLTVALVNQDRENNIEK--RSQGLKSEKEALLIGIIS 575
Query: 514 TFLHVHPFGASIEYICSYLHRLDNKICTSDVECLMGRLQHTFKQEMTGVGASLEKRWKFC 573
TFLHVHPFGA+IEY+ SY+ +LD+KI +++E L+ RL FKQE TGVGA+LEKRWK C
Sbjct: 576 TFLHVHPFGANIEYLWSYMQQLDSKISANEIEMLLMRLPRMFKQEFTGVGATLEKRWKLC 635
Query: 574 GFEGLKLT 581
FEG+K T
Sbjct: 636 AFEGIKTT 643
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 69.3 bits (168), Expect = 9e-12
Identities = 63/298 (21%), Positives = 131/298 (43%), Gaps = 48/298 (16%)
Query: 185 WECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSEAVQTLL 244
W+ ++RM ++ER R + EER+R + EK++++ K E Q
Sbjct: 503 WDQEERMWEQDERLREK--EERMR----------EQKKMWQQEEKMREEKKTQE--QEKK 548
Query: 245 TWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFE 304
TW + ++ ++ +R E+ M+E +EK ++
Sbjct: 549 TWDQEEKMREEER------MREREKKMREEEEMMREQEEKMQEQEEKMRE---------- 592
Query: 305 QIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEI 364
++K W+ K Q + +W ++ + D++ +EE M ++++
Sbjct: 593 ---------QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ--EQEEMMWEQEEKM 641
Query: 365 EEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQ 424
+E E +E + Q E ++E+ + ++ Q + R + E ++ ++ K+ +++ + Q+
Sbjct: 642 QEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQE 701
Query: 425 LKLL-QQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKESCASRLC 481
K+ Q+ Q+ + QEE ++KE E+++D K EKM E L E E S C
Sbjct: 702 EKMWGQEEKMWGQEEKMWGQEEMREKE---ERIRDQK---EKMQERLPEHEERCSEPC 753
Score = 58.9 bits (141), Expect = 1e-08
Identities = 68/328 (20%), Positives = 143/328 (43%), Gaps = 32/328 (9%)
Query: 185 WECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSEAVQTLL 244
WE +++M +EE+ R +EERL + + +K++D E +
Sbjct: 320 WEQEEKMREQEEKMWR--QEERLWE---------QEKQMREQEQKMRDQE---ERMWEQD 365
Query: 245 TWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKD--MEEAKEKFKQALSGILIQ 302
+ E R + + R EK E++ M E +EK ++ + Q
Sbjct: 366 ERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ 425
Query: 303 FEQIVAVYH-SASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMG----IRREEEM 357
E+ K+K W+ K Q + +W +Q E+IR+ +E+ G + R+E+M
Sbjct: 426 EEKEWQQQRLPEQKEKLWEQ-EKMQEQEEKIW-EQEEKIRD--QEEMWGQEKKMWRQEKM 481
Query: 358 EMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHRED 417
+D++ E E +E + Q E + E+++ LR + + R + ++ +QE+ RE+
Sbjct: 482 REQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKM--REE 539
Query: 418 DPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKESCA 477
+EQ+ K Q + ++ ++ +E+ ++E E+ + +++K+Q E ++
Sbjct: 540 KKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQ-----EQEEKMREQE 594
Query: 478 SRLCASNQDSEYPLEKTMNSSPIKSERE 505
++ + + EK E+E
Sbjct: 595 EKMWEQEEKMQEQEEKMWEQEEKMWEQE 622
Score = 52.0 bits (123), Expect = 1e-06
Identities = 65/304 (21%), Positives = 129/304 (42%), Gaps = 31/304 (10%)
Query: 185 WECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSEAVQTLL 244
W ++R+ RE+ + R +EE++R + + E ++L++ K E + +
Sbjct: 258 WRQEERL--REQEGKMREQEEKMRRQEKR--LREQEKELREQEKELREQKKLREQEEQMQ 313
Query: 245 TWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFE 304
E+ E + RL + EK M E ++K + + Q E
Sbjct: 314 ---EQEEKMWEQEEKMREQEEKMWRQEERLWEQ----EKQMREQEQKMRDQEERMWEQDE 366
Query: 305 QIVAVYHSASKQ-KAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDE 363
++ +Q K W+ K Q + + E + + +E +EE+M+ ++
Sbjct: 367 RLREKEERMREQEKMWEQEEKMQEEE-----RIREREKKMREEEETMREQEEKMQKQEEN 421
Query: 364 IEEMTETKETEESALVSQAEAL------KEENDSLRWQLDAYRNEVELLKQE-----QGK 412
+ E E KE ++ L Q E L +E+ + + Q + R++ E+ QE Q K
Sbjct: 422 MWEQEE-KEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEK 480
Query: 413 VHREDDPNKEQQLKLL--QQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENL 470
+ ++D EQ+ K+ +Q + ++ + + E ++KE + + K Q EKM E
Sbjct: 481 MREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEK 540
Query: 471 KEKE 474
K +E
Sbjct: 541 KTQE 544
Score = 50.8 bits (120), Expect = 3e-06
Identities = 35/144 (24%), Positives = 77/144 (53%), Gaps = 13/144 (9%)
Query: 335 KQAEEIRN----IHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEEND 390
+Q EE+R I E R+EE + + ++ E E +E L Q + L+E+
Sbjct: 238 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEK 297
Query: 391 SLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKE 450
LR Q R + E +++++ K+ +++ +EQ+ K+ +Q ++ L + +++ +++E
Sbjct: 298 ELREQ-KKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQ-----EERLWEQEKQMREQE 351
Query: 451 AELEKLKDDKLQVEKMLENLKEKE 474
+K++D + ++ + E L+EKE
Sbjct: 352 ---QKMRDQEERMWEQDERLREKE 372
Score = 48.1 bits (113), Expect = 2e-05
Identities = 33/121 (27%), Positives = 64/121 (52%), Gaps = 2/121 (1%)
Query: 354 EEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKV 413
+EEM ++E+ E + +E + Q E L+E+ +R Q + R + + L+ EQ K
Sbjct: 233 QEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLR-EQEKE 291
Query: 414 HREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEK 473
RE + +Q KL +Q Q MQ+ K+ E+ +K + EK+ + ++ + + ++E+
Sbjct: 292 LREQEKELREQKKLREQEEQ-MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ 350
Query: 474 E 474
E
Sbjct: 351 E 351
Score = 48.1 bits (113), Expect = 2e-05
Identities = 62/324 (19%), Positives = 134/324 (41%), Gaps = 29/324 (8%)
Query: 170 RLHVDFAQARDDLYEWECKQRMLA----REERHRRRMEEERLRPPSPP-----------P 214
RL + R+ WE +++M RE + R EEE +R
Sbjct: 367 RLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 426
Query: 215 VVHYSDHECSIVAEKLKDDSKFSEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRL 274
+ EKL + K E + + W + ++ + +R
Sbjct: 427 EKEWQQQRLPEQKEKLWEQEKMQEQEEKI--WEQEEKIRDQEEMWGQEKKMWRQEKMREQ 484
Query: 275 VNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKA-WDHFTKAQRKNISVW 333
++ E+ M + ++K + Q E++ +QK W K + + +
Sbjct: 485 EDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKT-- 542
Query: 334 CKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTET-KETEESALVSQAEALKEENDSL 392
Q +E + +E M R EE M + ++ E E +E EE + Q E ++E+ + +
Sbjct: 543 --QEQEKKTWDQEEKM--REEERMREREKKMREEEEMMREQEEK-MQEQEEKMREQEEKM 597
Query: 393 RWQLDAYRNEVE--LLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKE 450
W+ + E E + +QE+ +E++ ++Q +++ + + MQ+ K+ E+ +K
Sbjct: 598 -WEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR 656
Query: 451 AELEKLKDDKLQVEKMLENLKEKE 474
+ EK+++ + +++ E ++E+E
Sbjct: 657 EQEEKMREQEEKMQGQEEKMREQE 680
Score = 44.7 bits (104), Expect = 2e-04
Identities = 52/243 (21%), Positives = 117/243 (48%), Gaps = 38/243 (15%)
Query: 264 IQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFT 323
I++ + +R L +K E + +++ ++ G L + + + H + W
Sbjct: 87 IEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAGRLHHS-----WHFAG 141
Query: 324 KAQR--KNISVWCKQA----EEIRNIHNDELMGIRRE----EEMEMSDDEIEEMTETKET 373
+ QR +S W K+A EE+ + + + R EE++ + E++E E+
Sbjct: 142 ELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAES 201
Query: 374 EESALVSQAEALKEENDSLRWQL----------DAYRNEVEL-------LKQEQGKVHRE 416
E+S + + LK + + ++ L + +R E EL KQE+ K+ R+
Sbjct: 202 EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEE-KMWRQ 260
Query: 417 DDPNKEQQLKLLQQ--ALQGMQQHLLKVQEEYKKKEAEL---EKLKDDKLQVEKMLENLK 471
++ +EQ+ K+ +Q ++ ++ L + ++E +++E EL +KL++ + Q+++ E +
Sbjct: 261 EERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMW 320
Query: 472 EKE 474
E+E
Sbjct: 321 EQE 323
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 68.6 bits (166), Expect = 2e-11
Identities = 71/348 (20%), Positives = 152/348 (43%), Gaps = 28/348 (8%)
Query: 180 DDLYEWECK---QRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKF 236
+ + EWE K Q RE+ + R +EE++R + + E E++ + +
Sbjct: 368 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEE---MMWEKEEKMRRQEEMMWEKEE 424
Query: 237 SEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQAL 296
Q + W E+ E R + + +R EK ++ +E + K +
Sbjct: 425 KMRRQEEMMW-EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 483
Query: 297 SGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNIS------VWCKQAEEIRN-------- 342
I Q E+I +Q+ H + R+ +W +Q E+IR
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMW-RQEEKIREQEEIWRQK 542
Query: 343 --IHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYR 400
IH E ++EE+M ++++ + E +E + Q E ++E+ + +R Q + R
Sbjct: 543 EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIR 602
Query: 401 NEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDK 460
+ E+ ++++ K+ +++ EQ+ K+ +Q + M++ K++E+ KK + EK+++ +
Sbjct: 603 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE-EKMRRQEEKIREQEKKIREQEEKIREQE 661
Query: 461 LQVEKMLENLKEKESCASRLCASNQDSEYPLEKTMNSSPIKSEREALL 508
+++ E + E+E ++C + + EK E+E L
Sbjct: 662 EMMQEQEEKMWEQE---EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRL 706
Score = 64.3 bits (155), Expect = 3e-10
Identities = 63/296 (21%), Positives = 142/296 (47%), Gaps = 27/296 (9%)
Query: 186 ECKQRMLARE---ERHRRRMEEERLRPPSPPPVVHYSDHECSI--VAEKLKD-DSKFSEA 239
E +++M +E E+ +R EEE++R + E + EK+++ + K E
Sbjct: 442 ELEEKMHEQEKIREQEEKRQEEEKIREQEKR-----QEQEAKMWRQEEKIREQEEKIREQ 496
Query: 240 VQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGI 299
+ + W + +++ + Q R+ EK ++++ KEK + I
Sbjct: 497 EEKM--WRQEEKIHEQEKIREEEKRQEQEEMWRQ--EEKIREQEEIWRQKEKIHEQEEKI 552
Query: 300 LIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEM 359
Q E++ ++K D K + + VW +Q E+IR ++ IR +EE
Sbjct: 553 RKQEEKMWR-----QEEKMHDQEEKIREQEEKVW-RQEEKIR----EQEEKIREQEEKIR 602
Query: 360 SDDEIEEMTETKETE-ESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDD 418
+E+ + E K E E + Q E ++E+ + +R Q + R + + +++++ K+ +++
Sbjct: 603 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 662
Query: 419 PNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKE 474
+EQ+ K+ +Q + +Q K+QE+ +K + EK+ + ++++ + E ++E +
Sbjct: 663 MMQEQEEKMWEQEEKMCEQEE-KMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ 717
Score = 53.5 bits (127), Expect = 5e-07
Identities = 42/203 (20%), Positives = 109/203 (53%), Gaps = 12/203 (5%)
Query: 276 NEKAAHEKDMEEAKEKFKQALSGILIQFEQIVA-VYHSASKQKAWDHFTKAQRKNISVWC 334
+EK+ + +++E K K ++A +L+ +Q+ A H + ++ +AQ + +W
Sbjct: 296 SEKSEIQLNVKELKRKLERAK--LLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWN 353
Query: 335 KQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRW 394
+ N +E M R+EE+++ +++I+E E +E + Q E ++ + + +
Sbjct: 354 RL-----NQQQEEKMW-RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWE 407
Query: 395 QLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKE---A 451
+ + R + E++ +++ K+ R+++ E++ K+ + + +Q ++ QEE +++E
Sbjct: 408 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 467
Query: 452 ELEKLKDDKLQVEKMLENLKEKE 474
E EK ++ + ++ + E ++E+E
Sbjct: 468 EQEKRQEQEAKMWRQEEKIREQE 490
Score = 52.8 bits (125), Expect = 9e-07
Identities = 56/279 (20%), Positives = 123/279 (44%), Gaps = 29/279 (10%)
Query: 177 QARDDLYEWECKQRMLAR--EERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDS 234
Q + + E E +Q A+ + + R +EE++R + E EK++++
Sbjct: 461 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKM---WRQEEKIHEQEKIREEE 517
Query: 235 KFSEAVQTLLTWIERGEVNRRSANNFYSM---IQSANSHVRRLVNEKAAHEKDMEEAKEK 291
K E + W R E R + I +R+ + E+ M + +EK
Sbjct: 518 KRQEQEEM---W--RQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEK 572
Query: 292 FKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGI 351
+ EQ V+ K + + + Q + I ++ EE+ +E MG
Sbjct: 573 IR----------EQEEKVWRQEEKIREQEEKIREQEEKI----REQEEMTQ-EQEEKMG- 616
Query: 352 RREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQG 411
+EE+M +++++E E +E + Q + ++E+ + +R Q + + + E + +++
Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 676
Query: 412 KVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKE 450
K+ +++ +EQ+ K+ +Q + +Q + Q+E K +E
Sbjct: 677 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 715
Score = 47.4 bits (111), Expect = 4e-05
Identities = 30/160 (18%), Positives = 75/160 (46%), Gaps = 8/160 (5%)
Query: 315 KQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETE 374
++K W Q + I W ++ +E ++ IR +EE +E+ E K
Sbjct: 360 EEKMW-----RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 414
Query: 375 ESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQG 434
+ ++ + E + + W+ + E+E EQ K+ +++ +E++ Q+ Q
Sbjct: 415 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 474
Query: 435 MQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKE 474
+ + + +E+ +++E EK+++ + ++ + E + E+E
Sbjct: 475 QEAKMWRQEEKIREQE---EKIREQEEKMWRQEEKIHEQE 511
Score = 35.8 bits (81), Expect = 0.11
Identities = 38/181 (20%), Positives = 86/181 (47%), Gaps = 29/181 (16%)
Query: 354 EEEMEMSDDEIEEMTETKETEES-----------------------ALVSQAEALKEEND 390
+EE++ + +++E + E+E+S L ++A+ L +E
Sbjct: 277 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 336
Query: 391 SLRWQLDAYRNEVELL----KQEQGKVHREDDPNKEQQLKLLQQALQ-GMQQHLLKVQEE 445
S+ +L A E EL +Q++ K+ R+++ +E + K+ +Q + Q+ ++ QEE
Sbjct: 337 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEE 396
Query: 446 YKKKEAELEKLKDDKL-QVEKMLENLKEKESCASRLCASNQDSEYPLEKTMNSSPIKSER 504
+++ E+ K++K+ + E+M+ +EK + ++ LE+ M+ E+
Sbjct: 397 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 456
Query: 505 E 505
E
Sbjct: 457 E 457
Score = 34.3 bits (77), Expect = 0.32
Identities = 34/129 (26%), Positives = 63/129 (48%), Gaps = 18/129 (13%)
Query: 363 EIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKE 422
E+E+ T++ E L +E D+L L+ YRN + D+ KE
Sbjct: 237 ELEQALSAVATQKKKADRYIEELTKERDAL--SLELYRNTI------------TDEELKE 282
Query: 423 QQLKLLQQALQGMQQHLLKVQEEYK--KKEAELEKLKDDKLQVEKMLENL-KEKESCASR 479
+ K LQ+ LQ ++ ++Q K K++ E KL + Q++ ++L KE +S +++
Sbjct: 283 KNAK-LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 341
Query: 480 LCASNQDSE 488
L A +++E
Sbjct: 342 LQAQVEENE 350
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 63.9 bits (154), Expect = 4e-10
Identities = 89/424 (20%), Positives = 176/424 (41%), Gaps = 64/424 (15%)
Query: 120 EQCGEIIAIRKSKKNFCHIRFAEEYMVDK-ALYLSGYRIRLGSSTDKKDTGRLHVDFAQA 178
EQ +A +K K + R+ EE ++ AL L YR + K+ +L Q
Sbjct: 166 EQALSAVATQKKKAD----RYIEELTKERDALSLELYRNTITDEELKEKNAKL-----QE 216
Query: 179 RDDLYEWECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDH---ECSIVAEKLKDDSK 235
+ L E E + L +E +R++E +L P +DH E V+ KL+ +
Sbjct: 217 KLQLVESEKSEIQLNVKEL-KRKLERAKLLLPQQQLQAE-ADHLGKELQSVSAKLQAQVE 274
Query: 236 FSEAVQTL------LTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAK 289
+E L W + ++ R IQ +R + E+ M E +
Sbjct: 275 ENELWNRLNQQQEEKMWRQEEKIQEREEK-----IQEQEEKIREQEEKMRRQEEMMWEKE 329
Query: 290 EKFKQA-------------LSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQ 336
EK ++ L + + E+I +++ K Q + +W +Q
Sbjct: 330 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW-RQ 388
Query: 337 AEEIRNIHN------------DELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEA 384
E+IR +E MG +EE+M ++E++E E +E + Q +
Sbjct: 389 EEKIREQEEKIREQEEMMQEQEEKMG-EQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKK 447
Query: 385 LKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQE 444
++E+ + +R Q + + + E + +++GK+ ++ +EQ+ K+ +Q K++E
Sbjct: 448 IREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQE--------EKIRE 499
Query: 445 EYKKKEAELEKLKDDKLQVEKMLENLKEKESCASRLCASNQDSEYPLEKTMNSSPIKSER 504
+ KK + EK+++ + +++ E + E+E ++C + + EK E+
Sbjct: 500 QEKKIREQEEKIREQEEMMQEQEEKMWEQE---EKMCEQEEKMQEQEEKMRRQEEKMREQ 556
Query: 505 EALL 508
E L
Sbjct: 557 EVRL 560
Score = 58.9 bits (141), Expect = 1e-08
Identities = 41/192 (21%), Positives = 103/192 (53%), Gaps = 12/192 (6%)
Query: 282 EKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIR 341
E+ + E +EK ++ + Q E++ ++K W+ + Q + + +Q E+IR
Sbjct: 389 EEKIREQEEKIREQEEMMQEQEEKM-----GEQEEKMWEQEEEMQEQEEKMR-RQEEKIR 442
Query: 342 NIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEA-LKEENDSLRWQLDAYR 400
++ IR +EE +E+ + E K E+ + + EA ++E+ + +R Q + R
Sbjct: 443 ----EQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIR 498
Query: 401 NEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDK 460
+ + +++++ K+ +++ +EQ+ K+ +Q + +Q K+QE+ +K + EK+++ +
Sbjct: 499 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE-KMQEQEEKMRRQEEKMREQE 557
Query: 461 LQVEKMLENLKE 472
+++ + E ++E
Sbjct: 558 VRLRQQEEKMQE 569
Score = 54.7 bits (130), Expect = 2e-07
Identities = 50/260 (19%), Positives = 110/260 (42%), Gaps = 23/260 (8%)
Query: 179 RDDLYEWECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSE 238
R + WE ++++ EE+ E+E++R E EK+++ K E
Sbjct: 334 RQEEMMWEKEEKIRELEEKMH---EQEKIR----------EQEEKRQEEEKIREQEKRQE 380
Query: 239 AVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSG 298
+ E+ M+Q + + E++M+E +EK ++
Sbjct: 381 QEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEK 440
Query: 299 ILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEME 358
I EQ + K + + + Q + K E+ + E +EE+M
Sbjct: 441 IR---EQEKKIREQEEKIREQEEMMQEQEE------KMGEQEGKMCEQEAKMQEQEEKMR 491
Query: 359 MSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDD 418
+++I E + +E + Q E ++E+ + + Q + + E +++++ K+ R+++
Sbjct: 492 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 551
Query: 419 PNKEQQLKLLQQALQGMQQH 438
+EQ+++L QQ + MQ+H
Sbjct: 552 KMREQEVRLRQQE-EKMQEH 570
Score = 34.3 bits (77), Expect = 0.32
Identities = 34/129 (26%), Positives = 63/129 (48%), Gaps = 18/129 (13%)
Query: 363 EIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKE 422
E+E+ T++ E L +E D+L L+ YRN + D+ KE
Sbjct: 164 ELEQALSAVATQKKKADRYIEELTKERDAL--SLELYRNTI------------TDEELKE 209
Query: 423 QQLKLLQQALQGMQQHLLKVQEEYK--KKEAELEKLKDDKLQVEKMLENL-KEKESCASR 479
+ K LQ+ LQ ++ ++Q K K++ E KL + Q++ ++L KE +S +++
Sbjct: 210 KNAK-LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 268
Query: 480 LCASNQDSE 488
L A +++E
Sbjct: 269 LQAQVEENE 277
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 62.8 bits (151), Expect = 8e-10
Identities = 69/343 (20%), Positives = 149/343 (43%), Gaps = 27/343 (7%)
Query: 177 QARDDLYEWECKQRMLAR--EERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDS 234
Q + + E E +Q A+ + + R +EE++R + E EK++++
Sbjct: 414 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKM---WRQEEKIHEQEKIREEE 470
Query: 235 KFSEAVQTLLTWIERGEVN--------RRSANNFYSMIQSANSHVRRLVNEKAAHEKDME 286
K E + W + +++ + + I+ V R + E+ +
Sbjct: 471 KRQEQEEM---WRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR 527
Query: 287 EAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHND 346
E +EK + I Q E ++K W+ K Q + +W +Q E+IR
Sbjct: 528 EQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEE-EKRQEQEDKMW-RQEEKIRE---Q 582
Query: 347 ELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELL 406
E R+EE++ +++ +E E +E + Q E ++E+ + +R Q + R + E+
Sbjct: 583 EEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMT 642
Query: 407 KQEQGKVHREDDPNKEQQLKLLQQA-LQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEK 465
++++ K+ +++ EQ+ K+ +Q Q+ ++ QE KK + EK+++ + +++
Sbjct: 643 QEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQE--KKIREQEEKIREQEEMMQE 700
Query: 466 MLENLKEKESCASRLCASNQDSEYPLEKTMNSSPIKSEREALL 508
E + E+E ++C + + EK E+E L
Sbjct: 701 QEEKMWEQE---EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRL 740
Score = 58.5 bits (140), Expect = 2e-08
Identities = 43/200 (21%), Positives = 101/200 (50%), Gaps = 11/200 (5%)
Query: 277 EKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQ 336
EK E+ +E ++K + I Q E++ ++K + K Q + +W KQ
Sbjct: 557 EKIWEEEKRQEQEDKMWRQEEKIREQEEKVWR-----QEEKIREQEEKRQEQEEKMW-KQ 610
Query: 337 AEEIRN----IHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSL 392
E+IR I E +EE++ ++ +E E +E + Q E ++E+ +++
Sbjct: 611 EEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETM 670
Query: 393 RWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAE 452
Q + R + + +++++ K+ +++ +EQ+ K+ +Q + +Q K+QE+ +K +
Sbjct: 671 WRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE-KMQEQEEKMRRQ 729
Query: 453 LEKLKDDKLQVEKMLENLKE 472
EK+ + ++++ + E ++E
Sbjct: 730 EEKMWEQEVRLRQQEEKMQE 749
Score = 51.2 bits (121), Expect = 3e-06
Identities = 60/305 (19%), Positives = 131/305 (42%), Gaps = 24/305 (7%)
Query: 180 DDLYEWECK---QRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKF 236
+ + EWE K Q RE+ + R +EE++R + + E E++ + +
Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEE---MMWEKEEKMRRQEEMMWEKEE 363
Query: 237 SEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQAL 296
Q + W + ++ R+ M+ +R L E+ HE++ +E+ +Q
Sbjct: 364 KMRRQEEMMWEKEEKMRRQE-----EMMWEKEEKIREL--EEKMHEQEKIREQEEKRQEE 416
Query: 297 SGILIQF---EQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIR- 352
I Q EQ ++ K + + + Q K + ++ E I +E +
Sbjct: 417 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQE 476
Query: 353 ---REEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQE 409
R+EE +EI E +E + Q E + + + +R Q + R + E + ++
Sbjct: 477 EMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQ 536
Query: 410 QGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLEN 469
+ K+ +++ +E++ Q+ + + K QE+ K + EK+++ + +V + E
Sbjct: 537 EEKIREQEEMWREEEKMHEQEKIWEEE----KRQEQEDKMWRQEEKIREQEEKVWRQEEK 592
Query: 470 LKEKE 474
++E+E
Sbjct: 593 IREQE 597
Score = 51.2 bits (121), Expect = 3e-06
Identities = 68/322 (21%), Positives = 143/322 (44%), Gaps = 37/322 (11%)
Query: 179 RDDLYEWECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSE 238
R + WE ++++ EE+ E+E++R E EK+++ K E
Sbjct: 381 RQEEMMWEKEEKIRELEEKMH---EQEKIR----------EQEEKRQEEEKIREQEKRQE 427
Query: 239 AVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSG 298
Q W + ++ + + + EK E+ +E +E ++Q
Sbjct: 428 --QEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK- 484
Query: 299 ILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEME 358
+ + E+I K+K + K +++ VW +Q E+IR E +EE+M
Sbjct: 485 -IHEQEEIWR-----QKEKMHEQEEKIRKQEEKVW-RQEEKIRE---QEEKIREQEEKMW 534
Query: 359 MSDDEIEEMTETKETEESA----LVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVH 414
+++I E E EE + + E +E+ D + Q + R + E + +++ K+
Sbjct: 535 RQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIR 594
Query: 415 REDDPNKEQQLKLLQQALQ-GMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEK 473
+++ +EQ+ K+ +Q + Q+ ++ QEE K +E E EK+++ + ++ E + E+
Sbjct: 595 EQEEKRQEQEEKMWKQEEKIREQEEKIQEQEE-KIREQE-EKIREQEEMTQEQEEKMGEQ 652
Query: 474 ESCASRLCASNQDSEYPLEKTM 495
E ++C ++ E+TM
Sbjct: 653 E---EKMC-EQEEKMQEQEETM 670
Score = 50.4 bits (119), Expect = 4e-06
Identities = 51/259 (19%), Positives = 112/259 (43%), Gaps = 26/259 (10%)
Query: 185 WECKQRMLAREERHRRRME-----EERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSEA 239
W ++++ +EE+ R + E EE++R HE EK+ ++ K E
Sbjct: 513 WRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHE----QEKIWEEEKRQEQ 568
Query: 240 VQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGI 299
+ W + ++ + + +R ++ E+ M + +EK ++ I
Sbjct: 569 EDKM--WRQEEKIREQEEK-----VWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKI 621
Query: 300 LIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEM 359
Q E+I K + + T+ Q + K E+ + E +EE M
Sbjct: 622 QEQEEKI---REQEEKIREQEEMTQEQEE------KMGEQEEKMCEQEEKMQEQEETMWR 672
Query: 360 SDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDP 419
+++I E + +E + Q E ++E+ + + Q + + E +++++ K+ R+++
Sbjct: 673 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 732
Query: 420 NKEQQLKLLQQALQGMQQH 438
EQ+++L QQ + MQ+H
Sbjct: 733 MWEQEVRLRQQE-EKMQEH 750
Score = 49.3 bits (116), Expect = 1e-05
Identities = 43/234 (18%), Positives = 112/234 (47%), Gaps = 24/234 (10%)
Query: 276 NEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCK 335
+EK+ + +++E K K ++A +L+ +Q+ Q DH K + SV K
Sbjct: 235 SEKSEIQLNVKELKRKLERAK--LLLPQQQL---------QAEADHLGKELQ---SVSAK 280
Query: 336 QAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQ 395
++ + ++EE+M +++I+E E + +E + Q E ++E+ + +
Sbjct: 281 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM--- 337
Query: 396 LDAYRNEVELLKQEQGKVHREDDP--NKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAEL 453
R + E++ +++ K+ R+++ KE++++ ++ + ++ + + +E +KE ++
Sbjct: 338 ----RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 393
Query: 454 EKLKDDKLQVEKMLENLKEKESCASRLCASNQDSEYPLEKTMNSSPIKSEREAL 507
+L++ + EK+ E +EK ++ + E + I+ + E +
Sbjct: 394 RELEEKMHEQEKIREQ-EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 446
Score = 44.7 bits (104), Expect = 2e-04
Identities = 34/194 (17%), Positives = 92/194 (47%), Gaps = 18/194 (9%)
Query: 315 KQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEE-MEMSDDEIEEMTETKET 373
++K W Q + I W ++ +E ++ IR +EE M ++ + E E
Sbjct: 299 EEKMW-----RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 353
Query: 374 EESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQ 433
+E + + E ++ + + + + + R + E++ +++ K+ RE + +Q K+ +Q +
Sbjct: 354 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI-RELEEKMHEQEKIREQEEK 412
Query: 434 GMQQHLLKVQEEYKKKEAEL-----------EKLKDDKLQVEKMLENLKEKESCASRLCA 482
++ ++ QE+ +++EA++ EK+++ + ++ + E + E+E
Sbjct: 413 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR 472
Query: 483 SNQDSEYPLEKTMN 496
Q+ + E+ ++
Sbjct: 473 QEQEEMWRQEEKIH 486
Score = 35.0 bits (79), Expect = 0.19
Identities = 26/127 (20%), Positives = 64/127 (50%), Gaps = 7/127 (5%)
Query: 354 EEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVEL------LK 407
+EE++ + +++E + E+E+S + + LK + + + L + + E L+
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 275
Query: 408 QEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKML 467
K+ + + N E +L QQ + M + K+QE +K + + EK+++ + ++ +
Sbjct: 276 SVSAKLQAQVEEN-ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 334
Query: 468 ENLKEKE 474
E ++ +E
Sbjct: 335 EKMRRQE 341
Score = 34.3 bits (77), Expect = 0.32
Identities = 34/129 (26%), Positives = 63/129 (48%), Gaps = 18/129 (13%)
Query: 363 EIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKE 422
E+E+ T++ E L +E D+L L+ YRN + D+ KE
Sbjct: 176 ELEQALSAVATQKKKADRYIEELTKERDAL--SLELYRNTI------------TDEELKE 221
Query: 423 QQLKLLQQALQGMQQHLLKVQEEYK--KKEAELEKLKDDKLQVEKMLENL-KEKESCASR 479
+ K LQ+ LQ ++ ++Q K K++ E KL + Q++ ++L KE +S +++
Sbjct: 222 KNAK-LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 280
Query: 480 LCASNQDSE 488
L A +++E
Sbjct: 281 LQAQVEENE 289
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 60.8 bits (146), Expect = 3e-09
Identities = 64/308 (20%), Positives = 140/308 (45%), Gaps = 29/308 (9%)
Query: 180 DDLYEWECK---QRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKF 236
+ + EWE K Q RE+ + R +EE++R ++ + + E + + +
Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEE--MMWEKEEKMRRQEEMMWEKEEK 364
Query: 237 SEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQAL 296
++ ++ W E+ E R + + +R EK ++ +E + K +
Sbjct: 365 MRRLEEMM-W-EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 422
Query: 297 SGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMG----IR 352
I Q E+I ++K W Q + I K EE + +E+ IR
Sbjct: 423 EKIREQEEKI-----REQEKKMW-----RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR 472
Query: 353 REEEMEMSDDEIEEMTETKETEESA------LVSQAEALKEENDSLRWQLDAYRNEVELL 406
+EE+ +++ E + ++ EE + Q E ++E+ + + Q + R + E +
Sbjct: 473 EQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKI 532
Query: 407 KQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKM 466
++++ K+ +++ +EQ+ K+ +Q + +Q ++ QEE K +E E EK+++ K ++ +
Sbjct: 533 REQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEE-KIREQE-EKIREQKEKIREQ 590
Query: 467 LENLKEKE 474
E + E+E
Sbjct: 591 EEKIWEQE 598
Score = 51.6 bits (122), Expect = 2e-06
Identities = 42/203 (20%), Positives = 108/203 (53%), Gaps = 12/203 (5%)
Query: 276 NEKAAHEKDMEEAKEKFKQALSGILIQFEQIVA-VYHSASKQKAWDHFTKAQRKNISVWC 334
+EK+ + +++E K K ++A +L+ +Q+ A H + ++ +AQ + +W
Sbjct: 235 SEKSEIQLNVKELKRKLERAK--LLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWN 292
Query: 335 KQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRW 394
+ N +E M R+EE+++ +++I+E E +E + Q E ++ + + +
Sbjct: 293 RL-----NQQQEEKMW-RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWE 346
Query: 395 QLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKE---A 451
+ + R + E++ +++ K+ R ++ E++ K+ + + +Q ++ QEE +++E
Sbjct: 347 KEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 406
Query: 452 ELEKLKDDKLQVEKMLENLKEKE 474
E EK ++ + ++ + E ++E+E
Sbjct: 407 EQEKRQEQEAKMWRQEEKIREQE 429
Score = 48.9 bits (115), Expect = 1e-05
Identities = 52/283 (18%), Positives = 121/283 (42%), Gaps = 20/283 (7%)
Query: 177 QARDDLYEWECKQRMLAR--EERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDS 234
Q + + E E +Q A+ + + R +EE++R + E EK++++
Sbjct: 400 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKM---WRQEEKIHEQEKIREEE 456
Query: 235 KFSEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQ 294
K E + W + ++ + +R+ + E+ M + +EK ++
Sbjct: 457 KRQEQEEM---WRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIRE 513
Query: 295 ALSGILIQFEQI----VAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMG 350
+ Q E+I + K + + + Q + K E+ + E M
Sbjct: 514 QEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEE------KMGEQEEKMQEQEKMR 567
Query: 351 IRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQ 410
R+EE++ +++I E E +E + Q E ++E+ + ++ Q + + E + +++
Sbjct: 568 -RQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 626
Query: 411 GKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAEL 453
K+ +++ + Q+ K+ +Q ++ QQ K+QE + EA +
Sbjct: 627 EKMQEQEEKMRRQEEKMWEQEVRLRQQEE-KMQEHQEHLEAAI 668
Score = 48.5 bits (114), Expect = 2e-05
Identities = 63/305 (20%), Positives = 136/305 (44%), Gaps = 40/305 (13%)
Query: 186 ECKQRMLARE---ERHRRRMEEERLRPPSPPPVVHYSDHECSI--VAEKLKD-DSKFSEA 239
E +++M +E E+ +R EEE++R + E + EK+++ + K E
Sbjct: 381 ELEEKMHEQEKIREQEEKRQEEEKIREQEKR-----QEQEAKMWRQEEKIREQEEKIREQ 435
Query: 240 VQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGI 299
+ + W + +++ + Q R+ EK ++++ KEK + I
Sbjct: 436 EKKM--WRQEEKIHEQEKIREEEKRQEQEEMWRQ--EEKIREQEEIWRQKEKMHEQ-EKI 490
Query: 300 LIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHN---DELMGIRREEE 356
Q E++ ++K D K + + +W +Q E+IR ++ IR +EE
Sbjct: 491 RKQEEKVWR-----QEEKMHDQEEKIREQEEKMW-RQEEKIREQEEKIREQEEKIREQEE 544
Query: 357 MEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKV--- 413
M +E E K E+ + Q E ++E+ + +R Q + R + E + +++ K+
Sbjct: 545 MMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQ 604
Query: 414 ---HREDDPNK-EQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLEN 469
+E + EQ+ K+ +Q K+QE+ +K + EK+ + ++++ + E
Sbjct: 605 EEMMQEQEEKMWEQEEKMCEQE--------EKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 656
Query: 470 LKEKE 474
++E +
Sbjct: 657 MQEHQ 661
Score = 46.6 bits (109), Expect = 6e-05
Identities = 30/160 (18%), Positives = 75/160 (46%), Gaps = 8/160 (5%)
Query: 315 KQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETE 374
++K W Q + I W ++ +E ++ IR +EE +E+ E K
Sbjct: 299 EEKMW-----RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 353
Query: 375 ESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQG 434
+ ++ + E + + W+ + E+E EQ K+ +++ +E++ Q+ Q
Sbjct: 354 QEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 413
Query: 435 MQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKE 474
+ + + +E+ +++E EK+++ + ++ + E + E+E
Sbjct: 414 QEAKMWRQEEKIREQE---EKIREQEKKMWRQEEKIHEQE 450
Score = 35.8 bits (81), Expect = 0.11
Identities = 38/181 (20%), Positives = 86/181 (47%), Gaps = 29/181 (16%)
Query: 354 EEEMEMSDDEIEEMTETKETEES-----------------------ALVSQAEALKEEND 390
+EE++ + +++E + E+E+S L ++A+ L +E
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 275
Query: 391 SLRWQLDAYRNEVELL----KQEQGKVHREDDPNKEQQLKLLQQALQ-GMQQHLLKVQEE 445
S+ +L A E EL +Q++ K+ R+++ +E + K+ +Q + Q+ ++ QEE
Sbjct: 276 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEE 335
Query: 446 YKKKEAELEKLKDDKL-QVEKMLENLKEKESCASRLCASNQDSEYPLEKTMNSSPIKSER 504
+++ E+ K++K+ + E+M+ +EK + ++ LE+ M+ E+
Sbjct: 336 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQ 395
Query: 505 E 505
E
Sbjct: 396 E 396
Score = 34.3 bits (77), Expect = 0.32
Identities = 34/129 (26%), Positives = 63/129 (48%), Gaps = 18/129 (13%)
Query: 363 EIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKE 422
E+E+ T++ E L +E D+L L+ YRN + D+ KE
Sbjct: 176 ELEQALSAVATQKKKADRYIEELTKERDAL--SLELYRNTI------------TDEELKE 221
Query: 423 QQLKLLQQALQGMQQHLLKVQEEYK--KKEAELEKLKDDKLQVEKMLENL-KEKESCASR 479
+ K LQ+ LQ ++ ++Q K K++ E KL + Q++ ++L KE +S +++
Sbjct: 222 KNAK-LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 280
Query: 480 LCASNQDSE 488
L A +++E
Sbjct: 281 LQAQVEENE 289
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 59.7 bits (143), Expect = 7e-09
Identities = 54/258 (20%), Positives = 117/258 (45%), Gaps = 11/258 (4%)
Query: 262 SMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSA--SKQKAW 319
++I ++ LV +K +K ++L + Q + +A A SK +
Sbjct: 103 AIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQL 162
Query: 320 DHFTKAQRKNISVWCKQAE-EIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESAL 378
T RK + +Q + E+ N L+ R+EE + ++ + E E +E L
Sbjct: 163 QDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERL 222
Query: 379 VSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDP--NKEQQLKLLQQALQGMQ 436
Q E L+E+ + LR Q + + E L++ + ++ +++ +E++L+ ++ L +
Sbjct: 223 CEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQE 282
Query: 437 QHLLKVQEEYKKKEAEL----EKLKDDKLQVEKMLENLKEKES--CASRLCASNQDSEYP 490
+ L + +E +++E L E+L++ + ++ + E L+E+E C +
Sbjct: 283 ERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEE 342
Query: 491 LEKTMNSSPIKSEREALL 508
+EK + + E+E LL
Sbjct: 343 VEKLLEQERRQEEQERLL 360
Score = 50.4 bits (119), Expect = 4e-06
Identities = 46/205 (22%), Positives = 99/205 (48%), Gaps = 19/205 (9%)
Query: 268 NSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQR 327
N+ + L+N + E+ + E +E+ ++ + Q E++ +Q+ + R
Sbjct: 186 NNQMLSLLNRR--QEERLREQEERLREQEERLREQEERLCEQEERLREQE------ERLR 237
Query: 328 KNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKE 387
+ C+Q E +R H + L +EE + ++ + E E +E L Q E L+E
Sbjct: 238 EQEERLCEQEERLRE-HEERLC--EQEERLCEQEERLREQEERLHEQEERLCEQEERLRE 294
Query: 388 ENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYK 447
+ + L Q + R + E L +++ ++ +EQ+ +L +Q Q+ LL+ E+
Sbjct: 295 QEERLCEQEERLREQEERLCEQEERL-------REQEERLCEQEKLPGQERLLEEVEKLL 347
Query: 448 KKEAELEKLKDDKLQVEKMLENLKE 472
++E E+ ++ L+ E++LE ++E
Sbjct: 348 EQERRQEE-QERLLERERLLEEVEE 371
Score = 40.0 bits (92), Expect = 0.006
Identities = 58/287 (20%), Positives = 118/287 (41%), Gaps = 39/287 (13%)
Query: 191 MLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKD-DSKFSEAVQTLLTWIER 249
+L R + R R +EERLR E+L++ + + E + L E+
Sbjct: 192 LLNRRQEERLREQEERLREQE----------------ERLREQEERLCEQEERLR---EQ 232
Query: 250 GEVNRRSANNFYSMIQSANSHVRRLVNEK---AAHEKDMEEAKEKFKQALSGILIQFEQI 306
E R + H RL ++ E+ + E +E+ + + Q E++
Sbjct: 233 EERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERL 292
Query: 307 VAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEE 366
+Q+ + R+ C+Q E +R + L + E +E+E+
Sbjct: 293 REQEERLCEQE------ERLREQEERLCEQEERLRE-QEERLCEQEKLPGQERLLEEVEK 345
Query: 367 MTE-TKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQL 425
+ E + EE + + E L EE + L E E L+Q+ ++ +++ + ++L
Sbjct: 346 LLEQERRQEEQERLLERERLLEEVEELL--------EQERLRQQDERLWQQETLQELERL 397
Query: 426 KLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKE 472
+ L++ L+ + L + + E + EL LQ+E+ ++ LK+
Sbjct: 398 RELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELKK 444
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 58.9 bits (141), Expect = 1e-08
Identities = 82/374 (21%), Positives = 151/374 (40%), Gaps = 51/374 (13%)
Query: 156 RIRLGSSTDKKDTGRLHVDFAQARDDLYEWECKQRMLAREERHRRRMEEERLRPPSPPPV 215
R G K G L RD E EC+Q + + + ++E++
Sbjct: 1709 RAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQG------- 1761
Query: 216 VHYSDHECSIVAEKLKDDSKFSEAVQTLLTWIERGEVNRRSANNFYSMIQSA----NSHV 271
+H E S++ + + + + Q L E+GE+ +S + Q A + +
Sbjct: 1762 LHRKVGETSLLLSQREQEIVVLQ--QQLQEAREQGELKEQSLQSQLDEAQRALAQRDQEL 1819
Query: 272 RRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQR--KN 329
L E+ + E KEK AL G L Q + H + DH +A+R +
Sbjct: 1820 EALQQEQQQAQGQEERVKEK-ADALQGALEQAHMTLKERHGELQ----DHKEQARRLEEE 1874
Query: 330 ISVWCKQAEEIRNIHNDELMGIRREE------EMEMSDDEIEEMTETKETEESALVSQA- 382
++V ++ + + + D R +E + + ++ E ET+ ++S L +QA
Sbjct: 1875 LAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAV 1934
Query: 383 --------EALKEENDSLRWQLDAYRNEVELLKQEQGKVH-------------REDDPNK 421
EAL+ E+ S R Q +A R E L++ GK H E +
Sbjct: 1935 LKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSL 1994
Query: 422 EQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKESCASRLC 481
E LQ +L Q H +++E + +E E++ D L+ ++ ++ L++ +
Sbjct: 1995 EASTATLQASLDACQAHSRQLEEALRIQEGEIQ---DQDLRYQEDVQQLQQALAQRDEEL 2051
Query: 482 ASNQDSEYPLEKTM 495
Q+ E LEK++
Sbjct: 2052 RHQQEREQLLEKSL 2065
Score = 50.8 bits (120), Expect = 3e-06
Identities = 55/265 (20%), Positives = 116/265 (43%), Gaps = 38/265 (14%)
Query: 248 ERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIV 307
ER + + + Q+ L +KAAHEK++ + +EK+++ S
Sbjct: 818 ERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERS---------- 867
Query: 308 AVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEM 367
+H KA + +R+ + + + E+ + E + +REEE ++ + +M
Sbjct: 868 --WHQQELAKALE---SLEREKMELEMRLKEQQTEM---EAIQAQREEERTQAESALCQM 919
Query: 368 TETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKL 427
E E +L+ ++E QL+ R ++++ K ++ ++ +
Sbjct: 920 QLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKE-----------QETTGI 968
Query: 428 LQQALQGMQQHLLKVQEEYKKKEAELEK----LKDDKLQVEKMLENLKEK---ESCASRL 480
LQ LQ Q+ L + +++ A L++ L DK+ ++K +E+LK + + + RL
Sbjct: 969 LQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRL 1028
Query: 481 CASNQDSEYPLEKTMNSSPIKSERE 505
Q+ + L +T + I+ E E
Sbjct: 1029 V--EQEVQEKLRETQEYNRIQKELE 1051
Score = 43.5 bits (101), Expect = 5e-04
Identities = 60/322 (18%), Positives = 135/322 (41%), Gaps = 47/322 (14%)
Query: 238 EAVQTLLTWIERGEVNRRSANNFYSMIQSANS-------HVRRLVNEKAAHEKDMEEAKE 290
E + +L + + R E+ R A ++Q+A H++ V E A +E
Sbjct: 1320 ETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEE 1379
Query: 291 KFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRK----NISVWCKQAEEIRNIHND 346
+ A S + ++ E++ + A + AQ K N+++ + E
Sbjct: 1380 DLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAE------- 1432
Query: 347 ELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELL 406
REEE+E +I+E+ + +E +++AL + LK+ N ++D + +++ L
Sbjct: 1433 ------REEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQ----EVDLQQEQIQEL 1482
Query: 407 KQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEK- 465
++ + + +E++ KL Q Q ++E K +E + L+ L++EK
Sbjct: 1483 EKCRSVLEHLPMAVQEREQKLTVQREQ--------IRELEKDRETQRNVLEHQLLELEKK 1534
Query: 466 ---------MLENLKEKESCASRLCASNQDSEYPLE-KTMNSSPIKSEREALLVGIISTF 515
+++LK++ L +++ + +E + ++ +RE V +
Sbjct: 1535 DQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLT 1594
Query: 516 LHVHPFGASIEYICSYLHRLDN 537
L + ++ S +H L++
Sbjct: 1595 LDLEERSQELQAQSSQIHDLES 1616
Score = 42.4 bits (98), Expect = 0.001
Identities = 56/231 (24%), Positives = 105/231 (45%), Gaps = 40/231 (17%)
Query: 267 ANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQ 326
A R E A + +E KE+ +L L+Q ++ +A AS+Q +
Sbjct: 903 AQREEERTQAESALCQMQLETEKERV--SLLETLLQTQKELA---DASQQ------LERL 951
Query: 327 RKNISVWCKQAEEIRNIHNDELMGIRRE--EEMEMSDDEIEEMTETKETEESALVSQAEA 384
R+++ V + +E I +L +RE E D++ + E E S+L+
Sbjct: 952 RQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQE----ESSSLLQDKMD 1007
Query: 385 LKEENDSLRWQLDAYRNEVELLKQE-QGKVHREDDPN-------------------KEQQ 424
L+++ + L+ QL A + L++QE Q K+ + N KEQ+
Sbjct: 1008 LQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQR 1067
Query: 425 LKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKES 475
L +LQ+A QQ L ++++ ++ + E ++L Q+E + + +KEKE+
Sbjct: 1068 LLVLQEADSIRQQELSALRQDMQEAQGEQKEL---SAQMELLRQEVKEKEA 1115
Score = 37.0 bits (84), Expect = 0.050
Identities = 42/165 (25%), Positives = 80/165 (48%), Gaps = 8/165 (4%)
Query: 327 RKNISVWCKQAEEIRNIHND-ELMGIRREEEMEMSDDEIEEMTETKETEESALVS----Q 381
R+ + V ++A +R ++ + +L G + + E +E+ +E + L+ Q
Sbjct: 476 RQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQ 535
Query: 382 AEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLK 441
+E+L E +LR L++ E ELL+QEQ +V EQ + L + ++ +
Sbjct: 536 SESLSELI-TLREALESSHLEGELLRQEQTEV-TAALARAEQSIAELSSSENTLKTEVAD 593
Query: 442 VQEEYKKKEAELEKLKDDKLQVEKMLENLKEK-ESCASRLCASNQ 485
++ K A E L DK+ + + L L+E+ +S SR+ A+ Q
Sbjct: 594 LRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQ 638
Score = 36.6 bits (83), Expect = 0.065
Identities = 39/217 (17%), Positives = 103/217 (47%), Gaps = 12/217 (5%)
Query: 283 KDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRN 342
+DM+ K K ++ + Q ++ A++Q D Q ++ S+ + + +
Sbjct: 953 QDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHR-DDLAALQEESSSLLQDKMDLQKQ 1011
Query: 343 IHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRN- 401
+ + + + +++ + + E++E + +ET+E + + L+ E SL L
Sbjct: 1012 VEDLKSQLVAQDDSQRLVEQEVQE--KLRETQEYNRIQKE--LEREKASLTLSLMEKEQR 1067
Query: 402 -----EVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAE-LEK 455
E + ++Q++ R+D + + K L ++ ++Q + + + ++ +EA+ LE+
Sbjct: 1068 LLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEE 1127
Query: 456 LKDDKLQVEKMLENLKEKESCASRLCASNQDSEYPLE 492
L+ + +++ +L +E+ A++L + +E LE
Sbjct: 1128 LEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLE 1164
Score = 34.7 bits (78), Expect = 0.25
Identities = 69/313 (22%), Positives = 135/313 (43%), Gaps = 20/313 (6%)
Query: 165 KKDTGRLHVDFAQARDDLYEWECKQRMLAREERHRRRMEEERLRPPSPPPVV---HYSDH 221
++D +L VD+++ARD+L E + +M + + E RL V H+ +
Sbjct: 135 REDVEKLTVDWSRARDELMRKESQWQMEQEFFKGYLKGEHGRLLSLWREVVTFRRHFLEM 194
Query: 222 ECSIVAEKLKDDSKFSEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLV------ 275
+ + + ++ ++ +LLT R V +S S + L+
Sbjct: 195 KSATDRDLMELKAEHVRLSGSLLTCCLRLTVGAQSREPNGSGRMDGREPAQLLLLLAKTQ 254
Query: 276 -NEKAAHEKDMEEAKEKFKQALSGILIQ--FEQIVAVYHSASKQ-KAWDHFTKAQRKNIS 331
EK AHE+ E + K + L +Q ++ A+ + KQ + ++ KA R+ +
Sbjct: 255 ELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVE 314
Query: 332 VWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTE--TKETEESALVSQAEALKEEN 389
+ E+ H L +EE++ + I+++T+ +E + A S E E +
Sbjct: 315 ILETNHTELME-HEASLSRNAQEEKLSL-QQVIKDITQVMVEEGDNIAQGSGHENSLELD 372
Query: 390 DSLRWQLDAYRNEVELLKQEQGKV--HREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYK 447
S+ Q D Y++ + L + + R+ + QQL Q+A+ +QQ + +EE K
Sbjct: 373 SSIFSQFD-YQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGK 431
Query: 448 KKEAELEKLKDDK 460
L+KL ++
Sbjct: 432 ALRQRLQKLTGER 444
Score = 33.1 bits (74), Expect = 0.72
Identities = 32/153 (20%), Positives = 70/153 (45%), Gaps = 10/153 (6%)
Query: 337 AEEIRN-IHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQ 395
AE+ RN + D +R E + + +E + E + L + ++EE + ++ +
Sbjct: 636 AEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKK 695
Query: 396 LDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEK 455
L R++ E + ++H+E ++Q ++L +A+Q + + E E L+
Sbjct: 696 LSESRHQQEAATTQLEQLHQE----AKRQEEVLARAVQEKE----ALVREKAALEVRLQA 747
Query: 456 LKDDKLQVEKMLENLKE-KESCASRLCASNQDS 487
++ D+ + + L+ L KE S L + Q +
Sbjct: 748 VERDRQDLAEQLQGLSSAKELLESSLFEAQQQN 780
Score = 32.7 bits (73), Expect = 0.94
Identities = 26/119 (21%), Positives = 62/119 (52%), Gaps = 8/119 (6%)
Query: 364 IEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQ 423
+++ + E E AL + + L E D+L Q + EV+ L +E+ + + + Q
Sbjct: 419 LQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKARE-ELRQ 477
Query: 424 QLKLLQQALQGMQQHLLKV-------QEEYKKKEAELEKLKDDKLQVEKMLENLKEKES 475
QL++L+Q +++ +++ Q + ++++ EL ++ ++++ML L+ K+S
Sbjct: 478 QLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQS 536
Score = 32.0 bits (71), Expect = 1.6
Identities = 39/163 (23%), Positives = 77/163 (47%), Gaps = 25/163 (15%)
Query: 334 CKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLR 393
C++A + +D+ EEE + ++++T ++T L Q L+ E DSL
Sbjct: 412 CQEAVNLLQQQHDQW-----EEEGKALRQRLQKLTGERDT----LAGQTVDLQGEVDSLS 462
Query: 394 WQ-------LDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEY 446
+ + R ++E+L+QE ++ R + +L+L + QG ++ + QEE
Sbjct: 463 KERELLQKAREELRQQLEVLEQEAWRLRRVN-----VELQLQGDSAQGQKE---EQQEEL 514
Query: 447 KKKEAELEKLKDDKLQVE-KMLENLKEKESCASRLCASNQDSE 488
E E+L++ + +E K E+L E + L +S+ + E
Sbjct: 515 HLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGE 557
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 57.8 bits (138), Expect = 3e-08
Identities = 80/378 (21%), Positives = 165/378 (43%), Gaps = 36/378 (9%)
Query: 142 EEYMVDKALYLSGYRIRLGSSTDKKDTGR------LHVDFAQARDDLYEWECKQRMLARE 195
+ Y K + + +RLG T +K LH D A E K+R
Sbjct: 145 KNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSL 204
Query: 196 ERHRRRMEEERLRPPSPP--PVVHYSDHECSIVAEKLKDDSKFSEAVQTLLTWIERGEVN 253
E +R + +E L+ + + + E S + +KD + E Q LL +
Sbjct: 205 ELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQL---- 260
Query: 254 RRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSA 313
+ A+ +QS ++ ++ V E ++ +EK + Q E+I
Sbjct: 261 QVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWR-------QEEKI-----QE 308
Query: 314 SKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKET 373
++K + K + + +W +Q E++ H E +E++M +++I E E
Sbjct: 309 QEEKMCEQELKIREQEEKMW-RQEEKM---HEQEEKIREQEDKMWRQEEKIREQEEKIRE 364
Query: 374 EESALVSQAEALKEENDSLRWQLDA-YRNEVELLKQE---QGKVHREDDPNKEQQLKLLQ 429
+E + Q E ++E+++ ++ Q + +R E ++ +QE Q K+ R++ +EQ K+ +
Sbjct: 365 QEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIRE 424
Query: 430 QALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKESCASRLCASNQDSEY 489
Q + +Q K++E + + + EKL++ + ++++ E ++E+E R Q+ E
Sbjct: 425 QEEEMWRQEE-KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQE- 482
Query: 490 PLEKTMNSSPIKSEREAL 507
EKT + + E +
Sbjct: 483 --EKTWRQEKLLKQEEKI 498
Score = 57.8 bits (138), Expect = 3e-08
Identities = 50/209 (23%), Positives = 103/209 (49%), Gaps = 18/209 (8%)
Query: 282 EKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQ--KAW-------DHFTKAQRKNISV 332
E+ M E +EK ++ + Q E+I +Q K W + K Q + +
Sbjct: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
Query: 333 WCKQAEEIRNIHNDELMGI-RREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDS 391
W +Q E+IR + R+E++M D++I E E +E + E ++++ +
Sbjct: 391 W-RQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEK 449
Query: 392 LRWQLDAYRNEVELLKQEQGKVHREDDPNKEQ------QLKLLQQALQGMQQHLLKVQEE 445
LR + + E E +++++ K+ R+++ +EQ Q KLL+Q + +Q ++E
Sbjct: 450 LREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQE 509
Query: 446 YKKKEAELEKLKDDKLQVEKMLENLKEKE 474
K E E EK+++ + ++++ E ++E+E
Sbjct: 510 EKMWEQE-EKMQEQEEKMQRQEEKMREQE 537
Score = 55.1 bits (131), Expect = 2e-07
Identities = 43/212 (20%), Positives = 104/212 (49%), Gaps = 9/212 (4%)
Query: 271 VRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKA--WDHFTKAQRK 328
+R ++ E+ + E +EK ++ + Q E+I +Q+ W K + +
Sbjct: 341 IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQ 400
Query: 329 NISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEE 388
K + + + + +EEEM +++I E+ E + +E L E ++EE
Sbjct: 401 EEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEE 460
Query: 389 NDSLRWQLDAYRNEVELLKQEQGKVHREDDPNK------EQQLKLLQQALQGMQQHLLKV 442
+ ++ Q + + + E +++++ K R++ K EQ+ K+ +Q + M + K+
Sbjct: 461 EEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQE-EKMWEQEEKM 519
Query: 443 QEEYKKKEAELEKLKDDKLQVEKMLENLKEKE 474
QE+ +K + + EK+++ ++++ + E ++E+E
Sbjct: 520 QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 57.8 bits (138), Expect = 3e-08
Identities = 80/378 (21%), Positives = 165/378 (43%), Gaps = 36/378 (9%)
Query: 142 EEYMVDKALYLSGYRIRLGSSTDKKDTGR------LHVDFAQARDDLYEWECKQRMLARE 195
+ Y K + + +RLG T +K LH D A E K+R
Sbjct: 145 KNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSL 204
Query: 196 ERHRRRMEEERLRPPSPP--PVVHYSDHECSIVAEKLKDDSKFSEAVQTLLTWIERGEVN 253
E +R + +E L+ + + + E S + +KD + E Q LL +
Sbjct: 205 ELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQL---- 260
Query: 254 RRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSA 313
+ A+ +QS ++ ++ V E ++ +EK + Q E+I
Sbjct: 261 QVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWR-------QEEKI-----QE 308
Query: 314 SKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKET 373
++K + K + + +W +Q E++ H E +E++M +++I E E
Sbjct: 309 QEEKMCEQELKIREQEEKMW-RQEEKM---HEQEEKIREQEDKMWRQEEKIREQEEKIRE 364
Query: 374 EESALVSQAEALKEENDSLRWQLDA-YRNEVELLKQE---QGKVHREDDPNKEQQLKLLQ 429
+E + Q E ++E+++ ++ Q + +R E ++ +QE Q K+ R++ +EQ K+ +
Sbjct: 365 QEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIRE 424
Query: 430 QALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKESCASRLCASNQDSEY 489
Q + +Q K++E + + + EKL++ + ++++ E ++E+E R Q+ E
Sbjct: 425 QEEEMWRQEE-KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQE- 482
Query: 490 PLEKTMNSSPIKSEREAL 507
EKT + + E +
Sbjct: 483 --EKTWRQEKLLKQEEKI 498
Score = 57.8 bits (138), Expect = 3e-08
Identities = 50/209 (23%), Positives = 103/209 (49%), Gaps = 18/209 (8%)
Query: 282 EKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQ--KAW-------DHFTKAQRKNISV 332
E+ M E +EK ++ + Q E+I +Q K W + K Q + +
Sbjct: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
Query: 333 WCKQAEEIRNIHNDELMGI-RREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDS 391
W +Q E+IR + R+E++M D++I E E +E + E ++++ +
Sbjct: 391 W-RQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEK 449
Query: 392 LRWQLDAYRNEVELLKQEQGKVHREDDPNKEQ------QLKLLQQALQGMQQHLLKVQEE 445
LR + + E E +++++ K+ R+++ +EQ Q KLL+Q + +Q ++E
Sbjct: 450 LREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQE 509
Query: 446 YKKKEAELEKLKDDKLQVEKMLENLKEKE 474
K E E EK+++ + ++++ E ++E+E
Sbjct: 510 EKMWEQE-EKMQEQEEKMQRQEEKMREQE 537
Score = 55.1 bits (131), Expect = 2e-07
Identities = 43/212 (20%), Positives = 104/212 (49%), Gaps = 9/212 (4%)
Query: 271 VRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKA--WDHFTKAQRK 328
+R ++ E+ + E +EK ++ + Q E+I +Q+ W K + +
Sbjct: 341 IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQ 400
Query: 329 NISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEE 388
K + + + + +EEEM +++I E+ E + +E L E ++EE
Sbjct: 401 EEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEE 460
Query: 389 NDSLRWQLDAYRNEVELLKQEQGKVHREDDPNK------EQQLKLLQQALQGMQQHLLKV 442
+ ++ Q + + + E +++++ K R++ K EQ+ K+ +Q + M + K+
Sbjct: 461 EEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQE-EKMWEQEEKM 519
Query: 443 QEEYKKKEAELEKLKDDKLQVEKMLENLKEKE 474
QE+ +K + + EK+++ ++++ + E ++E+E
Sbjct: 520 QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 57.4 bits (137), Expect = 4e-08
Identities = 58/228 (25%), Positives = 109/228 (47%), Gaps = 26/228 (11%)
Query: 266 SANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKA 325
S V LV++ E+ + + KE+ K + S + + ++ S +K+K T+
Sbjct: 929 SNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEK---QVTEE 985
Query: 326 QRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDE-------IEEMTETKETEESAL 378
RKNI V K++ E + +LM + +E++ E+ DD+ ++++E K+T S
Sbjct: 986 VRKNIEVRLKESAEFQTQLEKKLMEVEKEKQ-ELQDDKRRAIESMEQQLSELKKTLSSVQ 1044
Query: 379 VSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQ---QALQGM 435
EAL+ + +L + A R+ QEQ K+ E E++L L +ALQ
Sbjct: 1045 NEVQEALQRASTALSNEQQARRD-----CQEQAKIAVEAQNKYERELMLHAADVEALQAA 1099
Query: 436 QQHLLK-------VQEEYKKKEAELEKLKDDKLQVEKMLENLKEKESC 476
++ + K ++E +K E++L + K + E+ML++ K C
Sbjct: 1100 KEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVC 1147
Score = 52.8 bits (125), Expect = 9e-07
Identities = 88/382 (23%), Positives = 156/382 (40%), Gaps = 56/382 (14%)
Query: 170 RLHVDFAQARDDLYEWECKQRMLAREERHRRRMEEE--RLRPPSPPPVVHYSDHECSIVA 227
+L +D ++ E K ML E ++ +EE+ R + + V D +
Sbjct: 1299 KLELDILPLQEANAELSEKSGMLQAE---KKLLEEDVKRWKARNQHLVSQQKDPDTEEYR 1355
Query: 228 EKLKDDSKFSEAVQTLLTWIER--GEVNRRSAN--NFYSMIQSANSHVRRLVNEKAAHEK 283
+ L + ++ +Q L I R E+ R +A+ N ++IQS + ++ EK +K
Sbjct: 1356 KLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQK 1415
Query: 284 DME----EAKEKFKQALSGILI------QFEQIVAVYHSA---SKQKAWDHFTKAQRKNI 330
D++ + +EK K I Q+E++ A S Q + DH Q +++
Sbjct: 1416 DLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDH----QEQHV 1471
Query: 331 SVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEEND 390
SV ++ +E++ N + + +E + +++ KETE L Q L+ E
Sbjct: 1472 SV--QEMQELKETLNQ---AETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELS 1526
Query: 391 SLRWQLDAYRNEVELLKQEQGKVHREDDPNKE-QQLKLLQQALQGMQQHLLKVQEEYKKK 449
LR L + E L+Q+ +E+ K K L G++ L K EE K++
Sbjct: 1527 RLRQDLQDRTTQEEQLRQQ--ITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQR 1584
Query: 450 EAELEKLKDD--------KLQVEKMLENL-KEKESCASRLCASNQDSEYPLEK------- 493
L++ KD+ K Q E + L +E R + + P K
Sbjct: 1585 NGALDQQKDELDVRITALKSQYEGRISRLERELREHQERHLEQRDEPQEPSNKVPEQQRQ 1644
Query: 494 -TMNSSPIKSEREALLVGIIST 514
T+ ++P ER GI ST
Sbjct: 1645 ITLKTTPASGER-----GIAST 1661
Score = 41.2 bits (95), Expect = 0.003
Identities = 48/175 (27%), Positives = 78/175 (44%), Gaps = 38/175 (21%)
Query: 346 DELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVEL 405
DEL+ + RE+ E+ E++ E K+ E S L Q LK N+ L+ ++ +++
Sbjct: 206 DELLALGREKGNEIL--ELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKE 263
Query: 406 LKQEQG----KVHRE----------------DDPNKEQQL--------KLLQ---QALQG 434
K++Q K H E D K +L KLL+ +A +
Sbjct: 264 AKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKA 323
Query: 435 MQQHLLKVQEEYKKKEAE-LEKLKDDKLQVEKMLENLKEKESCASRLCASNQDSE 488
+Q HLL+V++ + E E LEK+ ++EK LEN + S R A + E
Sbjct: 324 IQDHLLEVEQSKDQMEKEMLEKIG----RLEKELENANDLLSATKRKGAILSEEE 374
Score = 41.2 bits (95), Expect = 0.003
Identities = 46/209 (22%), Positives = 93/209 (44%), Gaps = 32/209 (15%)
Query: 277 EKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQ 336
EKA +EK E EK ++ ++ + ++Q IS
Sbjct: 685 EKAENEKIQNEQLEKLQEQVTDL------------------------RSQNTKISTQLDF 720
Query: 337 AEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSL---R 393
A + + D + G RR E+ + +++T T + +E + + + L+ N+ L
Sbjct: 721 ASKRYEMLQDNVEGYRR--EITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAE 778
Query: 394 WQLDAYRNEVELLKQEQGKV--HREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKK-E 450
+ + + E E+LK + ++ RE +++ LL LQ +Q L + + E K++
Sbjct: 779 VRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLS 838
Query: 451 AELEKLKDDKLQVEKMLENLKEKESCASR 479
+++EKL+ + ++K LEN E+ +R
Sbjct: 839 SQIEKLEHEISHLKKKLENEVEQRHTLTR 867
Score = 40.0 bits (92), Expect = 0.006
Identities = 31/144 (21%), Positives = 70/144 (48%), Gaps = 13/144 (9%)
Query: 347 ELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELL 406
++ +R + +E+ + E++E+ ++ E + A+ + + + ++ + E +
Sbjct: 1218 QVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMK------KTETMNV 1271
Query: 407 KQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKM 466
E K+ RE+ EQ L+ +Q ++ ++ +L +QE AEL + K LQ EK
Sbjct: 1272 VMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQE----ANAELSE-KSGMLQAEKK 1326
Query: 467 L--ENLKEKESCASRLCASNQDSE 488
L E++K ++ L + +D +
Sbjct: 1327 LLEEDVKRWKARNQHLVSQQKDPD 1350
Score = 38.5 bits (88), Expect = 0.017
Identities = 36/165 (21%), Positives = 81/165 (49%), Gaps = 13/165 (7%)
Query: 335 KQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETK---ETEESALVSQAEALKEENDS 391
KQ +EI + E + E ++ ++++E++ E ++ + + +Q + + +
Sbjct: 673 KQLQEIFENYKKE-----KAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEM 727
Query: 392 LRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHL--LKVQEEYKKK 449
L+ ++ YR E+ L + K+ +EQ + + Q L+G + L +V+ E KK
Sbjct: 728 LQDNVEGYRREITSLHERNQKLTATTQ-KQEQIINTMTQDLRGANEKLAVAEVRAENLKK 786
Query: 450 EAELEKLKDDKLQVEKMLENLKEKESCASRLCASNQDSEYPLEKT 494
E E+ KL + +L ++ E+L ++ + L + Q + LE++
Sbjct: 787 EKEMLKLSEVRLSQQR--ESLLAEQRGQNLLLTNLQTIQGILERS 829
Score = 34.7 bits (78), Expect = 0.25
Identities = 39/164 (23%), Positives = 76/164 (46%), Gaps = 22/164 (13%)
Query: 325 AQRKNISVWCK---QAEEIRNIHNDELMGIRRE------EEMEMSDDEIEEMTETKETEE 375
A+R+ + V K Q EE+ + E M + E EE E + ++++M E
Sbjct: 1244 AEREKVQVTAKTMAQHEEL--MKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLE 1301
Query: 376 SALVSQAEA---LKEENDSLRWQLDAYRNEVELLK-QEQGKVHREDDPNKEQQLKLLQQA 431
++ EA L E++ L+ + +V+ K + Q V ++ DP+ E+ KLL +
Sbjct: 1302 LDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEK 1361
Query: 432 LQGMQQHLLKVQ---EEYKKKEAELEKLKDDKLQVEKMLENLKE 472
+ H ++Q EE + +AE+ + + ++++LKE
Sbjct: 1362 ----EVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKE 1401
Score = 32.7 bits (73), Expect = 0.94
Identities = 51/252 (20%), Positives = 95/252 (37%), Gaps = 25/252 (9%)
Query: 269 SHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQK----------- 317
S R E A ++D+ E+ Q L + +++ ++ K
Sbjct: 111 SQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQ 170
Query: 318 AWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESA 377
A D K + K + +Q +E+ + N L E++ DE+ + K E
Sbjct: 171 ASDVSVKYREKRL----EQEKELLHSQNTWL-----NTELKTKTDELLALGREKGNEILE 221
Query: 378 LVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQ 437
L E KEE L Q++ + E L++ + + KEQQ + ++ +
Sbjct: 222 LKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNA 281
Query: 438 HLLKVQEEYKK----KEAELEKLKDDKLQVEKMLENLKEKESCASRLCASNQDSEYPLEK 493
H +K+ YK EA+ +L ++ K+L+ E + S+ +EK
Sbjct: 282 H-IKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEK 340
Query: 494 TMNSSPIKSERE 505
M + E+E
Sbjct: 341 EMLEKIGRLEKE 352
Score = 32.3 bits (72), Expect = 1.2
Identities = 57/295 (19%), Positives = 123/295 (41%), Gaps = 30/295 (10%)
Query: 240 VQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGI 299
V+ LLT ++ + + S + N+H++ K+A D EAK L+
Sbjct: 254 VEDLLTKLKEAKEQQASMEEKFH--NELNAHIKLSNLYKSA--ADDSEAKSN---ELTRA 306
Query: 300 LIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHND-----ELMGIRRE 354
+ + +++ A+K DH + ++ + + E+I + + +L+ +
Sbjct: 307 VEELHKLLKEAGEANKA-IQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKR 365
Query: 355 EEMEMSDDEIEEMTET------------KETE-ESALVSQAEAL---KEENDSLRWQLDA 398
+ +S++E+ M+ T K TE +A V + L K EN + LD
Sbjct: 366 KGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDE 425
Query: 399 YRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKD 458
EVE K K RE+ ++ + L L+ + + ++QE+ K + L+
Sbjct: 426 IVKEVEA-KAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLER 484
Query: 459 DKLQVEKMLENLKEKESCASRLCASNQDSEYPLEKTMNSSPIKSEREALLVGIIS 513
D ++E +++L ++ + + ++ ++S+ I S E + ++S
Sbjct: 485 DNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVS 539
Score = 31.2 bits (69), Expect = 2.7
Identities = 50/255 (19%), Positives = 98/255 (38%), Gaps = 42/255 (16%)
Query: 346 DELMGIRREEEMEMSD--DEIEEMTETKETEESALVSQAEALKEEND------------- 390
D+L+ R+ E +++D + ++ T E ++ + S E+L +E
Sbjct: 935 DDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRL 994
Query: 391 ----SLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEY 446
+ QL+ EVE KQE R + EQQL L++ L +Q + + +
Sbjct: 995 KESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRA 1054
Query: 447 K-------------KKEAELEKLKDDKLQVEKML-----ENLKEKESCASRLCASNQDSE 488
+++A++ +K + E ML E L+ + S++ + Q E
Sbjct: 1055 STALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLE 1114
Query: 489 YPLEKT----MNSSPIKSEREALLVGIISTFL-HVHPFGASIEYICSYLHRLDNKICTSD 543
+K + ERE +L +S + + + +L +K+ S
Sbjct: 1115 ETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASV 1174
Query: 544 VECLMGRLQHTFKQE 558
E + G L + +E
Sbjct: 1175 KEGVQGPLNVSLSEE 1189
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 57.0 bits (136), Expect = 5e-08
Identities = 107/521 (20%), Positives = 204/521 (39%), Gaps = 102/521 (19%)
Query: 17 NLGMAPLGIAGQPILPDFDPALGMMTGIPPITPMMPGLGIVPPPIPPDMPVVKEIIHCKS 76
+L P+GI P LP GIPP P PG PPP+PP P++ +
Sbjct: 6 HLNRPPMGI---PALPP---------GIPP--PQFPGF---PPPVPPGTPMIPVPM---- 44
Query: 77 CTLFPPNPNLPPPAT---------RERPPGCK------------TVFVGGLPENGTEQII 115
++ P P + P R+ PG K TVFVG + E ++ +I
Sbjct: 45 -SIMAPAPTVLVPTVSMVGKHLGARKDHPGLKAKENDENCGPTTTVFVGNISEKASDMLI 103
Query: 116 VEVFEQCGEIIAIRKSKK--------NFCHIRFAEEYMVDKALYLSGYRIRLGSSTDKKD 167
++ +CG +++ ++ + FC + E + +AL L + +++G +KK
Sbjct: 104 RQLLAKCGLVLSWKRVQGASGKLQAFGFCEYKEPESTL--RALRLL-HDLQIG---EKKL 157
Query: 168 TGRLHVDFAQARDDLYEWECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVA 227
++ A+ + L EW+ K++ R P +D E ++
Sbjct: 158 LVKVD---AKTKAQLDEWKAKKKASNGNAR----------------PETVTNDDEEALDE 198
Query: 228 EKLKDDSKFSEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEE 287
E + D A++ L+ R ++ + Q ++SH R+ EK E+
Sbjct: 199 ETKRRDQMIKGAIEVLI---------REYSSELNAPSQESDSHPRKKKKEK------KED 243
Query: 288 AKEKFKQA--LSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHN 345
+F A + LI E I A+ K+ R K+ EE +
Sbjct: 244 IFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDT----HKKLEEEKGKKE 299
Query: 346 DELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVEL 405
E I +E + E E +E E + E KE+ + D R+ +
Sbjct: 300 KERQEIEKERRERERERERERERRERERERE---REREREKEKERERERERDRDRDRTKE 356
Query: 406 LKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEK 465
+++ + R+ D ++E+ + + ++ + +E +++E E E+ ++ + + E+
Sbjct: 357 RDRDRDR-ERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERER 415
Query: 466 MLENLKEKESCASRLCASNQDSEYPLEKTMNSSPIKSEREA 506
E +E+E + +D E E+ ++ E+EA
Sbjct: 416 EREREREREREKDKKRDREEDEEDAYERRKLERKLR-EKEA 455
Score = 32.0 bits (71), Expect = 1.6
Identities = 57/304 (18%), Positives = 119/304 (39%), Gaps = 18/304 (5%)
Query: 184 EWECKQRMLARE-ERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSEAVQT 242
E E ++R RE ER RR E ER R + E E+ +D + E +
Sbjct: 306 EKERRERERERERERERRERERERERERE-----REKEKERERERERDRDRDRTKERDRD 360
Query: 243 LLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQ 302
+R RS++ +S R + E++ E +E+ ++ +
Sbjct: 361 RDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERE 420
Query: 303 FEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDD 362
E+ +++ + + ++ + K+A + N E+ ++ E E +
Sbjct: 421 REREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAE 480
Query: 363 EIEEMTETKETEESALVSQAEALKEENDSLRWQLDA-----YRNEVELLKQEQGKVHRED 417
EE E L E ++ D ++ + R+ + ++ ++ RE
Sbjct: 481 REEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREK 540
Query: 418 DPNKEQQLKLLQQA-------LQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENL 470
+ +E + +LL + LQ M+Q + ++ K+E E E+ +++K + E+ E
Sbjct: 541 EELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEP 600
Query: 471 KEKE 474
E+E
Sbjct: 601 MEEE 604
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 56.2 bits (134), Expect = 8e-08
Identities = 57/242 (23%), Positives = 120/242 (49%), Gaps = 29/242 (11%)
Query: 287 EAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHND 346
+A K +Q LS + + ++ A Y + W FTK K + +Q EE++ ++
Sbjct: 804 KAFAKKQQQLSALKV-LQRNCAAYLKLRHWQWWRVFTKV--KPLLQVTRQEEELQ-AKDE 859
Query: 347 ELMGIRREE-EMEMSDDEIEEMTETKETEESALVSQAEALKE---ENDSLRWQLDAYRNE 402
EL+ ++ ++ ++E +E+E + E++ L Q +A E E + +R +L A + E
Sbjct: 860 ELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQE 919
Query: 403 VE-LLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKL 461
+E +L + +V E++ N+ +LQ + MQ H+ ++E+ ++E +KL+ +K+
Sbjct: 920 LEEILHDLESRVEEEEERNQ-----ILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKV 974
Query: 462 ----QVEKMLEN-----------LKEKESCASRLCASNQDSEYPLEKTMNSSPIKSEREA 506
+++KM E +KEK+ R+ + EK N + I++++E
Sbjct: 975 TAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEV 1034
Query: 507 LL 508
++
Sbjct: 1035 MI 1036
Score = 45.1 bits (105), Expect = 2e-04
Identities = 52/234 (22%), Positives = 106/234 (45%), Gaps = 23/234 (9%)
Query: 248 ERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIV 307
E E R++ +QS + ++ V++ + +EEAK+K + + + E+
Sbjct: 1353 EEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKA 1412
Query: 308 AVYHSASK-----QKAWDHFT---KAQRKNIS-VWCKQAEEIRNIHNDELMGIRREEEME 358
Y K Q+ D T QR+ S + KQ + + + ++ + R EE +
Sbjct: 1413 LAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERD 1472
Query: 359 MSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGK-VHRED 417
++ E E ETK + + +A KEE + QL A ++ K + GK VH
Sbjct: 1473 RAEAEARE-KETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHE-- 1529
Query: 418 DPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLK 471
L+++ + ++Q + +++ + ++ E EL+ +D KL++E ++ +K
Sbjct: 1530 ----------LEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMK 1573
Score = 38.5 bits (88), Expect = 0.017
Identities = 44/224 (19%), Positives = 98/224 (43%), Gaps = 31/224 (13%)
Query: 264 IQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFT 323
+Q+ + + ++ ++ E ++EE + K +Q L I EQ+ Q + F
Sbjct: 854 LQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQL---------QAETELFA 904
Query: 324 KAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAE 383
+A+ + K+ E +H ++E +E EE + + E+ + + +
Sbjct: 905 EAEEMRARLAAKKQELEEILH-----------DLESRVEEEEERNQILQNEKKKMQAHIQ 953
Query: 384 ALKEENDS-----LRWQLDAYRNEVELLKQEQGKVHREDDPNK-EQQLKLLQQALQGMQQ 437
L+E+ D + QL+ E ++ K E+ + ED +K ++ KL++ +
Sbjct: 954 DLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSS 1013
Query: 438 HLLKVQEEYKKKEAELEKLKD-DKLQVEKMLENLKEKESCASRL 480
L + +E+ K L K+++ ++ + + E LK++E L
Sbjct: 1014 QLAEEEEKAK----NLAKIRNKQEVMISDLEERLKKEEKTRQEL 1053
Score = 36.2 bits (82), Expect = 0.085
Identities = 72/377 (19%), Positives = 148/377 (39%), Gaps = 61/377 (16%)
Query: 189 QRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDD-SKFSEAVQTLLTWI 247
+ L +EE+ R+ +E+ + + + E ++LK +K E +Q L
Sbjct: 1040 EERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALA-- 1097
Query: 248 ERGEVNRRSANNFYSMIQSANSHVRRLV----NEKAAHEK------DMEEAKEKFKQALS 297
RG+ NN +++ + + L +EKA+ K D+ E E K L
Sbjct: 1098 -RGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELE 1156
Query: 298 GIL----------IQFEQIVAVYHSASKQKAWDHFTKAQR---------KNISVWCKQAE 338
L + EQ VA A +++ +H + Q + +S +QA+
Sbjct: 1157 DTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAK 1216
Query: 339 EIRNIHNDELMGIRREEEMEMSD----DEIEEMTETKETEESALVSQAEALKEENDSLRW 394
+ G+ + + + +++ +E K + A V + A E D LR
Sbjct: 1217 RFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRV 1276
Query: 395 QL----DAYRNEVELLK------QEQGKVHREDDPNKEQQLKLLQQALQG---------- 434
+L +NE++ + +++G +D + E QL+ Q+ LQ
Sbjct: 1277 ELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSS 1336
Query: 435 ----MQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKESCASRLCASNQDSEYP 490
+++ +QE+ +++E + L+ L ++ L + K+K S ++++
Sbjct: 1337 RIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKK 1396
Query: 491 LEKTMNSSPIKSEREAL 507
L K + + E +AL
Sbjct: 1397 LLKDAEALSQRLEEKAL 1413
Score = 34.3 bits (77), Expect = 0.32
Identities = 58/310 (18%), Positives = 119/310 (38%), Gaps = 39/310 (12%)
Query: 186 ECKQRMLAREERHRRRMEEE------------RLRPPSPPPVVHYSDHECSIVAEKLKDD 233
E K+++L E +R+EE+ RL+ V DH+ + + K
Sbjct: 1392 EAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDL-DHQRQVASNLEKKQ 1450
Query: 234 SKFSEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFK 293
KF + + + R R A ++ + R + E +++ E ++ +
Sbjct: 1451 KKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLR 1510
Query: 294 QALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRN-IHNDELMGIR 352
+ ++ + + H K K +A + + Q EE+ + + E +R
Sbjct: 1511 ADMEDLMSSKDDVGKNVHELEKSK------RALEQQVEEMRTQLEELEDELQATEDAKLR 1564
Query: 353 REEEMEMSDDEIEEMTETK----ETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQ 408
E M+ + E +T+ E ++ L+ Q L+ E + R Q L
Sbjct: 1565 LEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQ--------RALAV 1616
Query: 409 EQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQV----- 463
K D + E Q++ +A + + L K+Q + K + ELE+ + + ++
Sbjct: 1617 ASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSK 1676
Query: 464 --EKMLENLK 471
EK L++L+
Sbjct: 1677 ESEKKLKSLE 1686
Score = 34.3 bits (77), Expect = 0.32
Identities = 46/209 (22%), Positives = 96/209 (45%), Gaps = 24/209 (11%)
Query: 272 RRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNIS 331
R L +A+ ++ ++KE K+ S ++ E + AS ++A H + +R +
Sbjct: 1659 RELEEARASRDEIFAQSKESEKKLKS---LEAEILQLQEELASSERARRH-AEQERDEL- 1713
Query: 332 VWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDS 391
A+EI N + + + + +E ++EE E +++ L + + D+
Sbjct: 1714 -----ADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDT 1768
Query: 392 LRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEA 451
L +L A R+ + + ++ R+ NKE + KL Q L+G V+ ++K A
Sbjct: 1769 LNAELAAERSAAQKSDNARQQLERQ---NKELKAKL--QELEG------AVKSKFK---A 1814
Query: 452 ELEKLKDDKLQVEKMLENLKEKESCASRL 480
+ L+ Q+E+ LE ++ + A++L
Sbjct: 1815 TISALEAKIGQLEEQLEQEAKERAAANKL 1843
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 56.2 bits (134), Expect = 8e-08
Identities = 58/317 (18%), Positives = 138/317 (43%), Gaps = 7/317 (2%)
Query: 189 QRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSEAVQTLLTWIE 248
+R+ REER ++R++E R P + +D S+ + ++++D+ +E +
Sbjct: 98 ERLARREERRQKRLQEALERQKEFDPTI--TDASLSLPSRRMQNDTAENETTEKEEKSES 155
Query: 249 RGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVA 308
R E R ++ +S + R E +K+ EE +E+ + G + + + V
Sbjct: 156 RQE--RYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEE--KPKRGSIGENQVEVM 211
Query: 309 VYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMT 368
V ++ + + IS + EE R +DE+ + EE + E E
Sbjct: 212 VEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERAR 271
Query: 369 ETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLL 428
E E Q + + +E + + A E E + E+ + RE++ ++ + +
Sbjct: 272 LEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRI 331
Query: 429 QQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKESCASRLCASNQDSE 488
++ + + +++EE K+ E +++K+++ + + + + +E +++ ++ +
Sbjct: 332 KEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQ 391
Query: 489 YPLEK-TMNSSPIKSER 504
+K M + IK E+
Sbjct: 392 LEEKKHAMQETKIKGEK 408
Score = 45.4 bits (106), Expect = 1e-04
Identities = 58/315 (18%), Positives = 133/315 (42%), Gaps = 29/315 (9%)
Query: 194 REERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSEAVQTLLTWIERGEVN 253
+E++ + EEE+ + S +++ ++ E+ +S+ V +L + G+++
Sbjct: 185 KEDKEKEEEEEEKPKRGS------IGENQVEVMVEEKTTESQEETVVMSL----KNGQIS 234
Query: 254 RRSANNFYSMIQSAN--SHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYH 311
Q ++ SH ++ E +K+ EA+ +A I+ EQ +
Sbjct: 235 SEEPKQEEEREQGSDEISHHEKMEEE----DKERAEAERARLEAEERERIKAEQDKKIAD 290
Query: 312 SASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETK 371
++ +A + +R+ ++AEE + +E + ++ + E +
Sbjct: 291 ERARIEAEEKAAAQERER-----REAEERERMREEEKRAAEERQRIKEEEKRAAEERQRI 345
Query: 372 ETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQA 431
+ EE + + +KEE + R E E E+ KV ++ + +QL+ + A
Sbjct: 346 KEEEKRAAEERQRIKEEEKRAAEERQRARAEEE----EKAKV---EEQKRNKQLEEKKHA 398
Query: 432 LQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKESCASRLCASNQDSEYPL 491
+Q + KV+++ + K +K ++DKLQ + + +EK + Q+ +
Sbjct: 399 MQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTF 458
Query: 492 EK-TMNSSPIKSERE 505
+K + IK ++E
Sbjct: 459 KKEEIKDEKIKKDKE 473
Score = 44.3 bits (103), Expect = 3e-04
Identities = 83/406 (20%), Positives = 165/406 (40%), Gaps = 48/406 (11%)
Query: 156 RIRLGSSTDKK---DTGRLHVDFAQARDDLYEWECKQRMLAREER-----HRRRMEEERL 207
R R+ + DKK + R+ + A + E ++R REE R+R++EE
Sbjct: 277 RERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEK 336
Query: 208 RPPSPPPVVHYSDHECSIVAEKLKDDSKFS--EAVQTLLTWIERGEVNRRSANNFYSMIQ 265
R + + + +++K++ K + E + E+ +V + N +
Sbjct: 337 RAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKK 396
Query: 266 SANSHVR------------RLVNEKAAHEKDMEEAKEKFKQALSGILIQF--EQIVAVYH 311
A + + VNEK A E ++ A K + G +Q E++
Sbjct: 397 HAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKP 456
Query: 312 SASKQKAWDHFTKAQR------KNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIE 365
+ K++ D K + K+ K E+++ + + + + E S
Sbjct: 457 TFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGR 516
Query: 366 EMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDD---PNKE 422
+TKE E + Q EA K + R + + E E LKQ+Q + E + +E
Sbjct: 517 ASVDTKEAEGAP---QVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKRE 573
Query: 423 QQLKLLQQALQGMQQ----HLLKVQEEYKKKEAELEKLKDDKLQ-----VEKMLENLKEK 473
++ K+L++ Q +Q L+ +EE ++ + E+E+ + + + E L + K+
Sbjct: 574 ERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKP 633
Query: 474 ESCASRLCAS---NQDSEYPLEKTMNSSPIKSEREALLVGIISTFL 516
C + +S + +E+ + SS +KS +A +V I + L
Sbjct: 634 FKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRL 679
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 55.5 bits (132), Expect = 1e-07
Identities = 62/287 (21%), Positives = 126/287 (43%), Gaps = 29/287 (10%)
Query: 224 SIVAEKLKDDSKFSEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEK 283
S V+E LKD + E +Q+L + + + N I N LV E + +
Sbjct: 2021 SDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELEN---QIAQLNKEKELLVKESESLQA 2077
Query: 284 DMEEA---KEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEI 340
+ E+ K +AL L++ + A+ S+++++ ++ + + +A+E
Sbjct: 2078 RLSESDYEKLNVSKALEAALVEKGEF-ALRLSSTQEEVHQLRRGIEKLRVRI---EADEK 2133
Query: 341 RNIHNDELMGIRREEEMEMSD--DEIEEMTETKETEESALVSQAEALKEENDSLRWQLDA 398
+ +H E + R E + D + +E + E + ++ AE K E ++L+ Q++
Sbjct: 2134 KQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEE 2193
Query: 399 YRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYK-----KKEAEL 453
+++ + + + E KE K +Q+ QG L K+ +K K++AE+
Sbjct: 2194 MARSLKVFELDLVTLRSE----KENLTKQIQEK-QGQLSELDKLLSSFKSLLEEKEQAEI 2248
Query: 454 EKLKDDKLQVEKMLENLKEKESCASRLC-------ASNQDSEYPLEK 493
+ ++ K VE + LKE + LC A+ Q + P+E+
Sbjct: 2249 QIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEE 2295
Score = 48.9 bits (115), Expect = 1e-05
Identities = 56/222 (25%), Positives = 96/222 (43%), Gaps = 19/222 (8%)
Query: 262 SMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDH 321
S ++ NS ++ EK + M+E + L L + + VA H+ +
Sbjct: 2409 SELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEA----- 2463
Query: 322 FTKAQRKNIS--VWCKQAEEIRNIHN-DELMG--IRREEEMEMSDDEIEE---MTETKET 373
KA+ +N+S V C + E+ + + DE I + + E+E+ E K+
Sbjct: 2464 -CKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDE 2522
Query: 374 EESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQ 433
E S L +Q + + + L +L E +L K EQ R EQ++++LQ
Sbjct: 2523 EISRLKNQIQ----DQEQLVSKLSQVEGEHQLWK-EQNLELRNLTVELEQKIQVLQSKNA 2577
Query: 434 GMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKES 475
+Q L +Q YK E ELE K DK+ + + + KE+
Sbjct: 2578 SLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKET 2619
Score = 46.2 bits (108), Expect = 8e-05
Identities = 41/164 (25%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Query: 351 IRREEEMEMSDDEIEEMT---ETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLK 407
I +E+ + DE+ T + T+ +AL + + L E+ R ++ R +E
Sbjct: 330 IEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKI 389
Query: 408 QEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKK----EAELEKLKDDKLQV 463
+E+ K +E+ +++ + L Q M+ L + ++ K +AEL+KL K Q+
Sbjct: 390 KEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQL 449
Query: 464 EKMLENLKEKESCASRLCASNQDSEYPLEKTMNSSPIKSEREAL 507
E LE K+K A + ++Q E L ++M +K E L
Sbjct: 450 ENNLEEFKQKLCRAEQAFQASQIKENELRRSMEE--MKKENNLL 491
Score = 42.0 bits (97), Expect = 0.002
Identities = 38/139 (27%), Positives = 71/139 (51%), Gaps = 13/139 (9%)
Query: 357 MEMSDDEIEEMTETKETEE-SALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHR 415
M + +E +E T+ ++ L Q + LK+E ++QLD+ E L KQ+Q KV
Sbjct: 1 MSWALEEWKEGLPTRALQKIQELEGQLDKLKKEKQQRQFQLDSL--EAALQKQKQ-KVEN 57
Query: 416 E--DDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELE----KLKDDKLQVEKMLEN 469
E + N +++ + L + + +++ K+ E + KE+++ +L K Q+EK+ +
Sbjct: 58 EKTEGTNLKRENQRLMEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQE 117
Query: 470 LKEKESCASRLCASNQDSE 488
LK C S L S Q ++
Sbjct: 118 LKR---CKSELERSQQAAQ 133
Score = 38.5 bits (88), Expect = 0.017
Identities = 64/332 (19%), Positives = 134/332 (40%), Gaps = 44/332 (13%)
Query: 171 LHVDFAQARDDLYEWECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKL 230
LH ++ RD L + K L E H+R L P +H+S +I+ E+
Sbjct: 756 LHAEYESLRDLL---KSKDASLVTNEDHQRS-----LLAFDQQPAMHHSF--ANIIGEQG 805
Query: 231 KDDSKFSEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKE 290
S+ SE R E ++ N+ +++Q+ + + + D+++ E
Sbjct: 806 SMPSERSEC---------RLEADQSPKNS--AILQNRVDSLEFSLESQKQMNSDLQKQCE 854
Query: 291 KFKQALSGI---LIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDE 347
+ Q I L++ EQ+ + + + Q+ +K Q + AE + + N E
Sbjct: 855 ELVQIKGEIEENLMKAEQMHQSFVAETSQR----ISKLQEDTSAHQNVVAETLSALENKE 910
Query: 348 LMGIRREEEMEMSDDEIEEMTETKETEESALVSQ---AEALKEENDSLRWQLDAYRNEVE 404
+++E EI+E+ ++ E +L +E L E + + + E+E
Sbjct: 911 KELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIE 970
Query: 405 LLKQEQGKVHREDDPNKEQQLKLLQQA------LQGMQQHLLKVQEEYKKKE-------A 451
L QE G + + ++++ L+Q++ + ++ + ++ ++YK+++
Sbjct: 971 ELTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCE 1030
Query: 452 ELEKLKDDKLQVEKMLENLKEKESCASRLCAS 483
E +D Q K + K C C S
Sbjct: 1031 ETGNAYEDLSQKYKAAQEKNSKLECLLNECTS 1062
Score = 38.5 bits (88), Expect = 0.017
Identities = 54/294 (18%), Positives = 119/294 (40%), Gaps = 43/294 (14%)
Query: 221 HECSIVAEKLKDDSK-----FSEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLV 275
+EC+ + E K++ + F++ Q LT + E + N +++ +R +
Sbjct: 1058 NECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAEERNQ---NLMLELETVQQALRSEM 1114
Query: 276 NEKAAHEKD-----------MEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTK 324
+ + K ++E + K ++ ++ +L + EQ++ V TK
Sbjct: 1115 TDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMK-----------TK 1163
Query: 325 AQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEA 384
+ +N+ ++E IRN + RE E + + + E KE + +Q
Sbjct: 1164 HECQNL-----ESEPIRNSVKE------RESERNQCNFKPQMDLEVKEISLDSYNAQLVQ 1212
Query: 385 LKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQE 444
L+ + +L E E L+ E + + + + Q ++ Q + G++ + +E
Sbjct: 1213 LEAMLRNKELKLQESEKEKECLQHELQTIRGDLETSNLQDMQ--SQEISGLKDCEIDAEE 1270
Query: 445 EYKKKEAELEKLKDDKLQVEKMLENLKEKESCASRLCASNQDSEYPLEKTMNSS 498
+Y EL ++D ++ L+ K + ++C Q +Y L +N S
Sbjct: 1271 KYISGPHELSTSQNDNAHLQCSLQTTMNKLNELEKICEILQAEKYELVTELNDS 1324
Score = 33.5 bits (75), Expect = 0.55
Identities = 27/136 (19%), Positives = 60/136 (44%), Gaps = 26/136 (19%)
Query: 362 DEIEEMTETKETEESALVSQAEALKEE----NDSLRWQLDAYRNEVELLKQEQGKVHRE- 416
+E+E++ E + E+ LV++ + E + ++ NEV++L + G +H E
Sbjct: 1301 NELEKICEILQAEKYELVTELNDSRSECITATRKMAEEVGKLLNEVKILNDDSGLLHGEL 1360
Query: 417 ----------DDPNKEQQLKL-----------LQQALQGMQQHLLKVQEEYKKKEAELEK 455
+ PN++ + L L + + +Q H ++QE++ ++E +
Sbjct: 1361 VEDIPGGEFGEQPNEQHPVSLAPLDESNSYEHLTLSDKEVQMHFAELQEKFLSLQSEHKI 1420
Query: 456 LKDDKLQVEKMLENLK 471
L D Q+ + L+
Sbjct: 1421 LHDQHCQMSSKMSELQ 1436
Score = 33.1 bits (74), Expect = 0.72
Identities = 51/270 (18%), Positives = 118/270 (43%), Gaps = 26/270 (9%)
Query: 247 IERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGIL-IQFEQ 305
+E ++++ S + + + + ++R ++E A +++E K L+G L + E+
Sbjct: 2597 LELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEE 2656
Query: 306 IVA--------VYHSASKQKAWDHFTKAQ-------RKNISVWCKQAEEIRNIHNDELMG 350
I + ++ +K+ D K Q R+ I+ + + E H L+
Sbjct: 2657 IKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLD 2716
Query: 351 IRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQ 410
++ E+E+ E +KE S+ + + LK + L L A +E LK+ +
Sbjct: 2717 TNKQYEVEIQT--YREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTK 2774
Query: 411 -------GKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQV 463
++ +E++ + ++KLL ++ + +++ +Q+E + +A EK K +
Sbjct: 2775 MDNLKYVNQLKKENE-RAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMD 2833
Query: 464 EKMLENLKEKESCASRLCASNQDSEYPLEK 493
K+ E E + L ++++ L+K
Sbjct: 2834 TKVDELTTEIKELKETLEEKTKEADEYLDK 2863
Score = 31.6 bits (70), Expect = 2.1
Identities = 36/174 (20%), Positives = 77/174 (44%), Gaps = 42/174 (24%)
Query: 338 EEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEA----------LKE 387
E +R +H E R+ ++E +E++E+ +E L+++ EA LK+
Sbjct: 1782 ENLRLLHVIE----DRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKK 1837
Query: 388 ENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYK 447
EN L +L+ + + + L Q +V + N + ++ + + + + ++ KV + +K
Sbjct: 1838 ENSDLSEKLEYFSCDHQELLQ---RVETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWK 1894
Query: 448 KK-------------------------EAELEKLKDDKLQVEKMLENLKEKESC 476
++ EA+LE ++ +KL +EK EN ++ C
Sbjct: 1895 ERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVC 1948
Score = 30.8 bits (68), Expect = 3.6
Identities = 39/234 (16%), Positives = 94/234 (40%), Gaps = 24/234 (10%)
Query: 253 NRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHS 312
N+ +N ++ ++ RL++ ++ +E + K+ S + +Q Q++ +
Sbjct: 1765 NQEDIHNLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEA 1824
Query: 313 ASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKE 372
+ + K + ++S E++ D ++R E E + ++E +
Sbjct: 1825 CIELEKIVGELKKENSDLS------EKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSS 1878
Query: 373 TEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHRED-----DPNKEQQLKL 427
E+ + + + NDS + + NE+ ++ E+ + E D Q KL
Sbjct: 1879 REDIG-----DNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKL 1933
Query: 428 L--------QQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEK 473
Q+ + +++ L V E + EL+ + ++++ E +KEK
Sbjct: 1934 CLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEK 1987
Score = 29.6 bits (65), Expect = 8.0
Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 1/62 (1%)
Query: 419 PNKEQQLKLLQQALQGMQQHL-LKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKESCA 477
P+ QLK Q L+ L L++Q K+ + ++ K ++ +LQ+EK L EKE
Sbjct: 277 PHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVL 336
Query: 478 SR 479
++
Sbjct: 337 NK 338
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 54.7 bits (130), Expect = 2e-07
Identities = 76/324 (23%), Positives = 143/324 (44%), Gaps = 54/324 (16%)
Query: 188 KQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSK--------FSEA 239
KQ + E +R++EEE + + S H+C ++ E+ +++ + S+A
Sbjct: 1309 KQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKA 1368
Query: 240 VQTLLTW--------IERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEK 291
+ W I+R E + +Q A HV VN K A +E+ K++
Sbjct: 1369 NSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHV-EAVNAKCA---SLEKTKQR 1424
Query: 292 FKQALSGILIQFEQIVAVYHSA-SKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMG 350
+ + ++I E+ A + KQ+ +D K ++ W ++ EE + EL
Sbjct: 1425 LQNEVEDLMIDVERTNAACAALDKKQRNFD-------KILAEWKQKCEET----HAELEA 1473
Query: 351 IRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQ 410
++E S E+ + K E +L Q E LK EN +L+ ++ ++ E
Sbjct: 1474 SQKE-----SRSLSTELFKIKNAYEESL-DQLETLKRENKNLQQEISDLTEQI----AEG 1523
Query: 411 GK-VHREDDPNK--EQQLKLLQQALQGMQQHL-------LKVQEEYKKKEAELE-KLKDD 459
GK +H + K EQ+ LQ AL+ + L L++Q E + ++E++ K+ +
Sbjct: 1524 GKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK 1583
Query: 460 KLQVEKMLEN-LKEKESCASRLCA 482
++++M N ++ ES S L A
Sbjct: 1584 DEEIDQMKRNHIRIVESMQSTLDA 1607
Score = 44.3 bits (103), Expect = 3e-04
Identities = 50/262 (19%), Positives = 116/262 (44%), Gaps = 25/262 (9%)
Query: 228 EKLKDDSKFSEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEE 287
E K ++K E + ++T ++ + + A +L+ K E ++E
Sbjct: 866 ELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKE 925
Query: 288 AKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDE 347
E+ + E+ + +A K+K D ++ ++ + A+ + H E
Sbjct: 926 VTERAED---------EEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 976
Query: 348 LMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSL------RWQLDAYRN 401
EEM D+ I ++T+ K+ + A + L+ E D + + +L+ +
Sbjct: 977 NKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVD 1036
Query: 402 EVELLKQEQGKVHREDDPNK---EQQLKLLQQALQGMQQHLLKVQEEYKKKEAEL----E 454
++E +++ K+ + + K E LKL Q++ ++ ++ E+ KKKE E+
Sbjct: 1037 DLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQS 1096
Query: 455 KLKDDK---LQVEKMLENLKEK 473
K++D++ +Q++K ++ L+ +
Sbjct: 1097 KIEDEQALGMQLQKKIKELQAR 1118
Score = 37.0 bits (84), Expect = 0.050
Identities = 45/233 (19%), Positives = 88/233 (37%), Gaps = 19/233 (8%)
Query: 326 QRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEAL 385
++K+ + E+I N+ + + + EM+M D++ ET + L AL
Sbjct: 1197 RKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRAL 1256
Query: 386 ----------KEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGM 435
+EE L L A R ++ E + E D Q + Q Q +
Sbjct: 1257 EDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQI 1316
Query: 436 QQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKESCASRL--CASNQDSE----- 488
++ +++EE K K A L+ + + + E +E++ + L S +SE
Sbjct: 1317 EELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWR 1376
Query: 489 --YPLEKTMNSSPIKSEREALLVGIISTFLHVHPFGASIEYICSYLHRLDNKI 539
Y + + ++ ++ L + HV A + RL N++
Sbjct: 1377 TKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEV 1429
Score = 34.3 bits (77), Expect = 0.32
Identities = 42/200 (21%), Positives = 82/200 (41%), Gaps = 18/200 (9%)
Query: 282 EKDMEEAKEKFKQA---LSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAE 338
E D ++ EK K+ +SG+ + E A+ K+ K + ++ E
Sbjct: 1074 ENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKI----------KELQARIEELE 1123
Query: 339 EIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKE---ENDSLRWQ 395
E I + + E++ E+EE++E E A +Q E K+ E +R
Sbjct: 1124 E--EIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRD 1181
Query: 396 LDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEK 455
L+ + E K H + +Q+ LQ+ Q +++ +++ E + +E
Sbjct: 1182 LEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMET 1241
Query: 456 LKDDKLQVEKMLENLKEKES 475
+ K +EKM L+++ S
Sbjct: 1242 VSKAKGNLEKMCRALEDQLS 1261
Score = 33.9 bits (76), Expect = 0.42
Identities = 34/148 (22%), Positives = 68/148 (45%), Gaps = 22/148 (14%)
Query: 337 AEEIRNIH--NDELMGIRREEEMEMS------DDEIEEMTETKETEESALVS---QAEAL 385
+E ++ +H N L+ +++ E ++S +D I+E +E + A+ AE L
Sbjct: 1714 SERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEEL 1773
Query: 386 KEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEE 445
K+E D+ +N + +K Q HR D+ Q AL+G ++ + K++
Sbjct: 1774 KKEQDTSAHLERMKKNLEQTVKDLQ---HRLDEAE--------QLALKGGKKQIQKLEAR 1822
Query: 446 YKKKEAELEKLKDDKLQVEKMLENLKEK 473
++ E E+E + ++ K L + K
Sbjct: 1823 VRELEGEVESEQKRNVEAVKGLRKHERK 1850
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 54.3 bits (129), Expect = 3e-07
Identities = 62/258 (24%), Positives = 117/258 (45%), Gaps = 27/258 (10%)
Query: 220 DHECSIVA---EKLKDDSKFSEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVN 276
D +CS V ++L++ + EA Q + R +V + +R+++
Sbjct: 529 DPKCSFVEKERQRLENLRRKEEAEQ-----LRRQKVEEDKRRRLEEVKLKREERLRKVLQ 583
Query: 277 EKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQ 336
+ E+ EE K++ +Q + I + E+ A +++KA + + + KQ
Sbjct: 584 ARERVEQMKEEKKKQIEQKFAQIDEKTEK--AKEERLAEEKAKKKAAAKKMEEVEARRKQ 641
Query: 337 AEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQL 396
EE R L +++EEE E + + KE E+ L AEA + L Q
Sbjct: 642 EEEAR-----RLRWLQQEEEERRHQ---ELLQKKKEEEQERLRKAAEAKR-----LAEQR 688
Query: 397 DAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKL 456
+ R E E +QE+ + R + +EQ+ +L +Q + +Q L+ + E +++E L
Sbjct: 689 EQERREQERREQERREQERREQERREQERQLAEQE-RRREQERLQAERELQEREKALRLQ 747
Query: 457 KDDKLQVEKMLENLKEKE 474
K+ Q+++ LE K+KE
Sbjct: 748 KE---QLQRELEEKKKKE 762
Score = 44.7 bits (104), Expect = 2e-04
Identities = 53/253 (20%), Positives = 99/253 (39%), Gaps = 17/253 (6%)
Query: 194 REERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSEAVQTLLTWIERGEVN 253
R E RR+ E E+LR D + KLK + + + +Q + E
Sbjct: 541 RLENLRRKEEAEQLRRQKVE-----EDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK 595
Query: 254 RRSANNFYSMIQSANSHVR--RLVNEKA---AHEKDMEEAKEKFKQALSGILIQFEQIVA 308
++ ++ I + RL EKA A K MEE + + KQ +++ Q
Sbjct: 596 KKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQ--- 652
Query: 309 VYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMT 368
+++ + +++ ++A E + + R +E E E E
Sbjct: 653 ---QEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERRE 709
Query: 369 ETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLL 428
+ + +E L Q ++E +L R + L++EQ + E+ KE+Q +L
Sbjct: 710 QERREQERQLAEQERRREQERLQAERELQE-REKALRLQKEQLQRELEEKKKKEEQQRLA 768
Query: 429 QQALQGMQQHLLK 441
++ LQ Q+ K
Sbjct: 769 ERQLQEEQEKKAK 781
Score = 30.8 bits (68), Expect = 3.6
Identities = 45/225 (20%), Positives = 86/225 (38%), Gaps = 38/225 (16%)
Query: 112 EQIIVEVFEQCGEIIAIRKSKKNFCHIRFAE-EYMVDKALYLSGYRIRLGSSTDKKDTGR 170
E+ + +V + + +++ KK +FA+ + +KA RL KK
Sbjct: 575 EERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAK-----EERLAEEKAKKKAAA 629
Query: 171 LHVDFAQARDDLYEWECKQRMLAREERHRRRM---------EEERLRPPSPPPVVHYSDH 221
++ +AR E + R L +EE RR E+ERLR +
Sbjct: 630 KKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAA---------- 679
Query: 222 ECSIVAEKLKDDSKFSEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAH 281
E +AE+ + + + E + ER E RR Q R+L ++
Sbjct: 680 EAKRLAEQREQERREQERREQ-----ERREQERRE--------QERREQERQLAEQERRR 726
Query: 282 EKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQ 326
E++ +A+ + ++ + +Q EQ+ K++ + Q
Sbjct: 727 EQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQ 771
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 53.5 bits (127), Expect = 5e-07
Identities = 63/310 (20%), Positives = 144/310 (46%), Gaps = 29/310 (9%)
Query: 185 WECKQRMLAREERHRRRMEE-ERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSEAVQTL 243
WE +R+ +EER R + + E++ + + + EK++++ + E + +
Sbjct: 400 WEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKM 459
Query: 244 L----TWIERGEVNRRSANNFYSMIQSANSHVRRLVN--EKAAHEKDMEEAKEKFKQALS 297
T E+ E ++ N + + +RL EK ++ M+E +EK +
Sbjct: 460 REEEETMREQEEKMQKQEENMWEQ-EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 518
Query: 298 GILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHN-----DELMGIR 352
I Q E ++K W K + + +W +Q E++R+ +E M +
Sbjct: 519 KIRDQEEMW------GQEKKMWRQ-EKMREQEDQMW-EQEEKMRDQEQKMWDQEERMEKK 570
Query: 353 REEEMEMSDDEIEEMTETKETEE--SALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQ 410
+E+ + + D+ E+M E + E + + E ++E+ + ++ Q + + + E + +++
Sbjct: 571 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQE 630
Query: 411 GKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEE---YKKKEAELEKLKDDKLQV---E 464
K+ +++ EQ+ K+ +Q + +Q L Q+E +K E EK+++ + ++ E
Sbjct: 631 EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQE 690
Query: 465 KMLENLKEKE 474
KM + +E+E
Sbjct: 691 KMEKKTQEQE 700
Score = 50.8 bits (120), Expect = 3e-06
Identities = 36/144 (25%), Positives = 77/144 (53%), Gaps = 13/144 (9%)
Query: 335 KQAEEIRN----IHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEEND 390
+Q EE+R I E R+EE + + ++ E E +E L Q + L+E+
Sbjct: 276 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEK 335
Query: 391 SLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKE 450
LR Q + E ++ +QE+ K+ +++ +EQ+ K+ +Q ++ L + +++ +++E
Sbjct: 336 ELREQKELREQEEQMQEQEE-KMWEQEEKMREQEEKMWRQ-----EERLWEQEKQMREQE 389
Query: 451 AELEKLKDDKLQVEKMLENLKEKE 474
+K++D + ++ + E L+EKE
Sbjct: 390 ---QKMRDQEERMWEQDERLREKE 410
Score = 50.8 bits (120), Expect = 3e-06
Identities = 44/212 (20%), Positives = 103/212 (48%), Gaps = 25/212 (11%)
Query: 282 EKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQA--EE 339
E+ M+E +EK ++ + Q E++ ++K W+ K + +W +Q E+
Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKM-----QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQ 663
Query: 340 IRNIHNDELMG----IRREEEMEMSDDEIEEMTETKE--TEESALVSQAEALKEENDSLR 393
+ E M ++ +EE +++E+ T+ +E T + + + E+++E +R
Sbjct: 664 KEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMR 723
Query: 394 WQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLL-----------KV 442
+ + R + E +++++ K+ +++ EQ+ K+ +Q + +Q L K+
Sbjct: 724 EEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM 783
Query: 443 QEEYKKKEAELEKLKDDKLQVEKMLENLKEKE 474
QE+ K E E EK++D + ++ E ++ +E
Sbjct: 784 QEQEKIWEQE-EKMRDQEEKMRGQEEKMRGQE 814
Score = 50.4 bits (119), Expect = 4e-06
Identities = 49/224 (21%), Positives = 101/224 (45%), Gaps = 17/224 (7%)
Query: 274 LVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQ--KAW--DHFTKAQRKN 329
L E E+++ E ++K ++ + Q E++ +Q K W + + Q K
Sbjct: 270 LQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKE 329
Query: 330 ISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEEN 389
+ K+ E + + E +EE+M ++++ E E +E L Q + ++E+
Sbjct: 330 LREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 389
Query: 390 DSLR------WQLDAYRNEVELLKQEQGKVH------REDDPNKEQQLKLLQQALQGMQQ 437
+R W+ D E E +EQ K+ RE+ +EQ+ K Q + ++
Sbjct: 390 QKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEE 449
Query: 438 HLLKVQEEYKKKEAELEKLKDDKLQV-EKMLENLKEKESCASRL 480
++ +E+ ++E E + +++K+Q E+ + +EKE RL
Sbjct: 450 ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRL 493
Score = 48.1 bits (113), Expect = 2e-05
Identities = 43/197 (21%), Positives = 90/197 (45%), Gaps = 13/197 (6%)
Query: 282 EKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQ-KAWDHFTKAQRKNISVWCKQAEEI 340
EK M E ++K + + Q E++ +Q K W+ K + + K+ +E
Sbjct: 382 EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREE------KKMQEQ 435
Query: 341 RNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYR 400
D+ ++ EE + + ++ E ET +E + Q E + E+ + WQ
Sbjct: 436 EKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK-EWQQQRLP 494
Query: 401 NEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAEL----EKL 456
+ E L EQ K+ +++ EQ+ K+ Q Q+ + QE+ +++E ++ EK+
Sbjct: 495 EQKEKL-WEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM 553
Query: 457 KDDKLQVEKMLENLKEK 473
+D + ++ E +++K
Sbjct: 554 RDQEQKMWDQEERMEKK 570
Score = 48.1 bits (113), Expect = 2e-05
Identities = 66/329 (20%), Positives = 142/329 (43%), Gaps = 54/329 (16%)
Query: 185 WECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSEAVQTLL 244
WE +++M R++ + +EER+ + D E EK++++ + E + +
Sbjct: 547 WEQEEKM--RDQEQKMWDQEERMEKKTQEQEKKTWDQE-----EKMREEERMREREKKMR 599
Query: 245 TWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFE 304
E E+ R + ++ + E+ M+E +EK + + Q E
Sbjct: 600 ---EEEEMMREQEEKMQEQEEKMQEQEEKMWEQ----EEKMQEQEEKMWEQEEKMWEQEE 652
Query: 305 QIVAVYH-SASKQKAWDHFT-----KAQRKNISVW------CKQAEEIRNIHNDELMG-- 350
++ K+K W+H K Q + +W K E+ + + E M
Sbjct: 653 KMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREE 712
Query: 351 ---------IRREEEMEMSDDE-IEEMTETKETEESALVSQAEALKEENDSLRWQLDAYR 400
+R EEEM +E ++E E + +E + Q E + E+ + + W+
Sbjct: 713 ESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKM-WEQQRLP 771
Query: 401 NEVELL-----KQEQGKVHREDDPNKEQQLKL--LQQALQGMQQHLLKVQEEYKKKEAEL 453
+ E L QEQ K+ +++ ++Q+ K+ ++ ++G ++ + +E+ +E ++
Sbjct: 772 EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKM 831
Query: 454 ----EKL--KDDKL--QVEKMLENLKEKE 474
EK+ +++K+ Q EKM E ++ +E
Sbjct: 832 WGQEEKMWGQEEKMWGQEEKMEEKMQGQE 860
Score = 46.2 bits (108), Expect = 8e-05
Identities = 57/304 (18%), Positives = 126/304 (41%), Gaps = 18/304 (5%)
Query: 185 WECKQRMLAREERHRRRME-----EERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSEA 239
W ++R+ +E + R + E E+RLR + + E E + + + E
Sbjct: 296 WRQEERLREQEGKMREQEEKMWRQEKRLREQEKE--LREQEKELREQKELREQEEQMQEQ 353
Query: 240 VQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGI 299
+ + E+ + +R + E+ M E E+ ++ +
Sbjct: 354 EEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM 413
Query: 300 LIQ---FEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEE 356
Q +EQ+ + K + + T+ Q + + + E + + +E +EE+
Sbjct: 414 REQEKMWEQVEKM-REEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEK 472
Query: 357 MEMSDDEIEEMTETKETEESALVSQAEAL------KEENDSLRWQLDAYRNEVELLKQEQ 410
M+ ++ + E E KE ++ L Q E L +E+ + + Q + R++ E+ QE+
Sbjct: 473 MQKQEENMWEQEE-KEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEK 531
Query: 411 GKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENL 470
+E +E Q+ ++ ++ +Q + +E +KK E EK D+ + + E +
Sbjct: 532 KMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERM 591
Query: 471 KEKE 474
+E+E
Sbjct: 592 RERE 595
Score = 44.3 bits (103), Expect = 3e-04
Identities = 46/208 (22%), Positives = 96/208 (46%), Gaps = 21/208 (10%)
Query: 276 NEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCK 335
+EK+ + +++E K K ++A +L Q + +++ K RK +
Sbjct: 239 SEKSEIQLNVKELKRKLERA-KFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWR 297
Query: 336 QAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQ 395
Q E +R E G RE+E +M E + KE E Q + L+E+ + LR Q
Sbjct: 298 QEERLR-----EQEGKMREQEEKMWRQEKRLREQEKELRE-----QEKELREQKE-LREQ 346
Query: 396 LDAYRNEVELLKQEQGKVHREDDP---------NKEQQLKLLQQALQGMQQHLLKVQEEY 446
+ + + E + +++ K+ +++ +E+Q++ +Q ++ ++ + + E
Sbjct: 347 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL 406
Query: 447 KKKEAELEKLKDDKLQVEKMLENLKEKE 474
++KE + + + QVEKM E K +E
Sbjct: 407 REKEERMREQEKMWEQVEKMREEKKMQE 434
Score = 42.4 bits (98), Expect = 0.001
Identities = 32/132 (24%), Positives = 70/132 (53%), Gaps = 18/132 (13%)
Query: 355 EEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRW----------QLDAYRNEVE 404
EE++ + E++E E+E+S + + LK + + ++ Q + +R E E
Sbjct: 221 EELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 280
Query: 405 LLKQE------QGKVHREDDPNKEQQLKLLQQ--ALQGMQQHLLKVQEEYKKKEAELEKL 456
L +QE + K+ R+++ +EQ+ K+ +Q + ++ L + ++E +++E EL +
Sbjct: 281 LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQ 340
Query: 457 KDDKLQVEKMLE 468
K+ + Q E+M E
Sbjct: 341 KELREQEEQMQE 352
Score = 40.4 bits (93), Expect = 0.005
Identities = 54/316 (17%), Positives = 135/316 (42%), Gaps = 39/316 (12%)
Query: 185 WECKQRMLARE---ERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSEAVQ 241
W+ +++M E ER ++ EEE + + + + + + K E +
Sbjct: 579 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEE 638
Query: 242 TLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILI 301
+ W E+ E + + + +EK ++ M+E +EK +
Sbjct: 639 KM--W-EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWE------- 688
Query: 302 QFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEM---- 357
++ + ++K WD + +++ K+ E + ++ ++ +EE
Sbjct: 689 --QEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQ 746
Query: 358 --EMSDDEIEEMTETKET--EESALVSQAEALKE-----ENDSLRWQLDAYRNEVELLKQ 408
EM + E E+M E +E E+ L Q E L E E + + Q + R++ E ++
Sbjct: 747 EEEMWEQE-EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRG 805
Query: 409 EQGKVHREDDPNKEQQLKL---------LQQALQGMQQHLLKVQEEYKKK-EAELEKLKD 458
++ K+ +++ + Q+ K+ ++ + G ++ + +E+ ++K + + EK+++
Sbjct: 806 QEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMRE 865
Query: 459 DKLQVEKMLENLKEKE 474
+ ++ E ++E+E
Sbjct: 866 QEEKMRGQEEKMREQE 881
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 53.5 bits (127), Expect = 5e-07
Identities = 40/211 (18%), Positives = 104/211 (49%), Gaps = 18/211 (8%)
Query: 264 IQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFT 323
+Q V++ + E+ M E +E+ ++ +L Q EQ + +++
Sbjct: 243 VQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQE 302
Query: 324 KAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAE 383
+ R+ +Q E++R +E MG ++EE+M +++ E E +E + Q E
Sbjct: 303 EQMREQEEQMREQEEQMRE--QEEQMG-KQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEE 359
Query: 384 ALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQ 443
++++ + +R Q + R + E +++++ ++ ++++ EQ+ ++ +Q +
Sbjct: 360 QMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQ------------K 407
Query: 444 EEYKKKEAELEKLKDDKLQVEKMLENLKEKE 474
E+ +++E E++ + K Q+ K E++ E++
Sbjct: 408 EQMREQE---EQMGEQKEQMRKQEEHMGEQK 435
Score = 53.1 bits (126), Expect = 7e-07
Identities = 28/140 (20%), Positives = 79/140 (56%), Gaps = 4/140 (2%)
Query: 335 KQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRW 394
+Q E+++ +E MG +EE+M ++++ E E + +E + Q E ++++ + +R
Sbjct: 210 EQEEQMQK--QEEQMG-EQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMRE 266
Query: 395 QLDAYRNEVE-LLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAEL 453
Q + R + E +LKQ++ E +E+Q++ ++ ++ ++ + + +E+ +++E ++
Sbjct: 267 QEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQM 326
Query: 454 EKLKDDKLQVEKMLENLKEK 473
K ++ + ++ + KE+
Sbjct: 327 GKQEEQMWEQKEQMWEQKEQ 346
Score = 52.4 bits (124), Expect = 1e-06
Identities = 44/194 (22%), Positives = 95/194 (48%), Gaps = 13/194 (6%)
Query: 282 EKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIR 341
E+ M++ +E+ + + Q EQ+ KQ+ + Q + KQ E++R
Sbjct: 212 EEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMR------KQEEQMR 265
Query: 342 NIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRN 401
+E M R +EE + E E E +E + Q E ++E+ + +R Q + R
Sbjct: 266 --EQEEQM--REQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMRE 321
Query: 402 EVELLKQEQGKVHREDDPNKEQQLKLLQQALQ-GMQQHLLKVQEEYKKKEAELEKLKDDK 460
+ E + +++ ++ + + EQ+ ++ +Q Q G Q+ ++ QEE +K+ E+++ +
Sbjct: 322 QEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQE--EQMRKQE 379
Query: 461 LQVEKMLENLKEKE 474
Q+ K E ++++E
Sbjct: 380 EQMRKQEEQMRKQE 393
Score = 51.2 bits (121), Expect = 3e-06
Identities = 24/122 (19%), Positives = 71/122 (58%), Gaps = 2/122 (1%)
Query: 353 REEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGK 412
+EE+M ++++++ E +E + Q E + E+ + ++ Q + + + E +++++ +
Sbjct: 204 QEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQ 263
Query: 413 VHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKE 472
+ +++ +EQ+ ++L+Q Q Q+ QEE +++ E++++ + Q+ + E ++E
Sbjct: 264 MREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQE--EQMREQEEQMREQEEQMRE 321
Query: 473 KE 474
+E
Sbjct: 322 QE 323
Score = 48.9 bits (115), Expect = 1e-05
Identities = 39/219 (17%), Positives = 97/219 (44%), Gaps = 27/219 (12%)
Query: 264 IQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFT 323
++ VR + E M E +E+ + + Q EQ+ KQ+
Sbjct: 180 VREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEE----- 234
Query: 324 KAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAE 383
+ E+ + E ++EE+M ++++ E E +E ++ Q E
Sbjct: 235 -----------QMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKE 283
Query: 384 ALK------EENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQ 437
+ E+ + +R Q + R + E +++++ ++ +++ +Q+ ++ +Q Q +Q
Sbjct: 284 QTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQ 343
Query: 438 --HLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKE 474
+ K +E+ ++E +++K ++ QV K E ++++E
Sbjct: 344 KEQMWKQEEQMGEQEEQMQKQEE---QVRKQEEQMRKQE 379
Score = 47.8 bits (112), Expect = 3e-05
Identities = 35/198 (17%), Positives = 93/198 (46%), Gaps = 6/198 (3%)
Query: 282 EKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQ----KAWDHFTKAQRKNISVWCKQA 337
E+ M + +E+ + + Q EQ+ KQ + + + Q + + +Q
Sbjct: 226 EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT 285
Query: 338 EEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLD 397
E+ E +EE+M ++++ E E +E + Q E + E+ + + Q +
Sbjct: 286 EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKE 345
Query: 398 A-YRNEVELLKQEQGKVHREDDPNK-EQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEK 455
++ E ++ +QE+ +E+ K E+Q++ ++ ++ ++ + K +E+ +++ ++ +
Sbjct: 346 QMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGE 405
Query: 456 LKDDKLQVEKMLENLKEK 473
K+ + E+ + KE+
Sbjct: 406 QKEQMREQEEQMGEQKEQ 423
Score = 46.2 bits (108), Expect = 8e-05
Identities = 40/204 (19%), Positives = 97/204 (47%), Gaps = 18/204 (8%)
Query: 271 VRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNI 330
+R+ + E+ +++ +E+ ++ + Q EQ+ +Q+ K Q +
Sbjct: 229 MRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQE 288
Query: 331 SVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEEND 390
+Q E++R +E M +EE+M ++++ E E +E + Q E + E+ +
Sbjct: 289 EQTGEQEEQMRE--QEEQMR-EQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKE 345
Query: 391 SLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKE 450
+ W+ + E E Q+Q E+Q++ ++ ++ ++ + K +E+ +K+E
Sbjct: 346 QM-WKQEEQMGEQEEQMQKQ-----------EEQVRKQEEQMRKQEEQMRKQEEQMRKQE 393
Query: 451 AELEKLKDDKLQVEKMLENLKEKE 474
E++ + K Q+ + E ++E+E
Sbjct: 394 ---EQMGEQKEQMGEQKEQMREQE 414
Score = 40.4 bits (93), Expect = 0.005
Identities = 26/136 (19%), Positives = 72/136 (52%), Gaps = 8/136 (5%)
Query: 347 ELMGIRREEEMEMSDDE--IEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVE 404
E G RE+E ++ + E + E +E + Q ++E+ +R Q R +
Sbjct: 126 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 185
Query: 405 LLKQEQGKVHREDDP--NKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAEL----EKLKD 458
+++++G++ ++ +E+Q+ ++ +Q ++ + + +E+ +K+E ++ E+++
Sbjct: 186 QVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQK 245
Query: 459 DKLQVEKMLENLKEKE 474
+ QV+K E ++++E
Sbjct: 246 QEEQVQKQEEQMRKQE 261
Score = 40.0 bits (92), Expect = 0.006
Identities = 34/157 (21%), Positives = 72/157 (45%), Gaps = 12/157 (7%)
Query: 347 ELMGIRREEEMEMSDDE--IEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVE 404
E G RE+E ++ + E + E +E + Q ++E+ +R Q R +
Sbjct: 105 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 164
Query: 405 LLKQEQGKVHREDDPNKEQQLKLLQQALQ--------GMQQHLLKVQEEYKKKEAELEKL 456
+++++G+V ++ +EQ+ ++ +Q Q G Q+ + QEE +K+ E++
Sbjct: 165 QVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQE--EQM 222
Query: 457 KDDKLQVEKMLENLKEKESCASRLCASNQDSEYPLEK 493
+ + Q+ K E + E+E + Q E + K
Sbjct: 223 GEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRK 259
Score = 37.4 bits (85), Expect = 0.038
Identities = 32/151 (21%), Positives = 73/151 (48%), Gaps = 9/151 (5%)
Query: 347 ELMGIRREEEMEMSDDE--IEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVE 404
E G RE+E ++ + E + E +E + Q ++E+ + Q + E
Sbjct: 147 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEE 206
Query: 405 LLKQEQGKVHREDDPNKEQQLKLLQQALQ-GMQQHLLKVQEEYKKKEAELEKLKDDKL-- 461
+ +++ ++ ++++ EQ+ ++ +Q Q G Q+ ++ QEE +K+ E + +++++
Sbjct: 207 QMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMRE 266
Query: 462 QVEKMLEN----LKEKESCASRLCASNQDSE 488
Q E+M E LK+KE Q+ +
Sbjct: 267 QEEQMREQEEQMLKQKEQTEQEEQTGEQEEQ 297
Score = 36.2 bits (82), Expect = 0.085
Identities = 28/123 (22%), Positives = 66/123 (53%), Gaps = 4/123 (3%)
Query: 355 EEMEMSDDEIEEMTETKETEESALVSQAEALKE--ENDSLRWQLDAYRNEVE-LLKQEQG 411
EE++ + E++E + ETE+S + + LK E D + + E E +++++G
Sbjct: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
Query: 412 KVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLK 471
+V ++ +EQ+ ++ +Q Q +Q ++E + +E E ++++ + QV + ++
Sbjct: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE-GQVREQEGQVREQEGQVR 125
Query: 472 EKE 474
E+E
Sbjct: 126 EQE 128
Score = 36.2 bits (82), Expect = 0.085
Identities = 29/136 (21%), Positives = 66/136 (48%), Gaps = 8/136 (5%)
Query: 347 ELMGIRREEEMEMSDDE--IEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVE 404
E G RE+E ++ + E + E +E + Q ++E+ +R Q R +
Sbjct: 91 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 150
Query: 405 LLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAE------LEKLKD 458
+++++G+V ++ +EQ+ ++ +Q Q +Q ++E + E E E++ +
Sbjct: 151 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGE 210
Query: 459 DKLQVEKMLENLKEKE 474
+ Q++K E + E+E
Sbjct: 211 QEEQMQKQEEQMGEQE 226
Score = 35.8 bits (81), Expect = 0.11
Identities = 26/151 (17%), Positives = 76/151 (50%), Gaps = 4/151 (2%)
Query: 324 KAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAE 383
+ ++ I + K+ + R + D++ + +E ++ + ++ E +E + Q
Sbjct: 24 ETEKSEIQLHIKELK--RKLETDKIP-LPQEGQVREQEGQVREQEGQVREQEGQVREQEG 80
Query: 384 ALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQ 443
++E+ +R Q R + +++++G+V ++ +EQ+ ++ +Q Q +Q +
Sbjct: 81 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 140
Query: 444 EEYKKKEAELEKLKDDKLQVEKMLENLKEKE 474
+E + +E E ++++ + QV + ++E+E
Sbjct: 141 QEGQVREQE-GQVREQEGQVREQEGQVREQE 170
Score = 34.7 bits (78), Expect = 0.25
Identities = 27/130 (20%), Positives = 65/130 (50%), Gaps = 3/130 (2%)
Query: 347 ELMGIRREEEMEMSDDE--IEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVE 404
E G RE+E ++ + E + E +E + Q ++E+ +R Q R +
Sbjct: 70 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 129
Query: 405 LLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVE 464
+++++G+V ++ +EQ+ ++ +Q Q +Q ++E + +E E ++++ + QV
Sbjct: 130 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE-GQVREQEGQVR 188
Query: 465 KMLENLKEKE 474
+ + E+E
Sbjct: 189 EQEGQMGEQE 198
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 52.8 bits (125), Expect = 9e-07
Identities = 51/241 (21%), Positives = 106/241 (43%), Gaps = 15/241 (6%)
Query: 274 LVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKA-----WDHFTKAQRK 328
L+++ EK ++E + K S + + V HSA K+ + + F Q K
Sbjct: 775 LLSQLNVLEKQLQETQTKNDFLKSEV----HDLRVVLHSADKELSSVKLEYSSFKTNQEK 830
Query: 329 NISVWCKQAEEIR-NIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKE 387
+ ++ ++ + N L + E D + + E + E L + K+
Sbjct: 831 EFNKLSERHMHVQLQLDNLRLENEKLLESKACLQDSYDNLQEIMKFEIDQLSRNLQNFKK 890
Query: 388 ENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYK 447
EN++L+ L+ +E K+ K+ + + +KE K + + L+ ++Q K + +
Sbjct: 891 ENETLKSDLNNLMELLEAEKERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKETAKCE 950
Query: 448 KKEAELEKLKDDKLQVEKMLENLKEKESCASRLCAS--NQDSEY---PLEKTMNSSPIKS 502
++ A+++KL++ L EK++ +L++ ++ A NQ E EKT +K
Sbjct: 951 QQMAKVQKLEESLLATEKVISSLEKSRDSDKKVVADLMNQIQELRTSVCEKTETIDTLKQ 1010
Query: 503 E 503
E
Sbjct: 1011 E 1011
Score = 37.7 bits (86), Expect = 0.029
Identities = 32/124 (25%), Positives = 62/124 (50%), Gaps = 11/124 (8%)
Query: 338 EEIRN-IHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQL 396
EE+++ ++N E+ +R +E+E + + + KE L S+ E + EE + ++
Sbjct: 1271 EEVQSALYNKEMECLRMTDEVERTQTLESKAFQEKEQ----LRSKLEEMYEERERTSQEM 1326
Query: 397 DAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKL 456
+ R +VE L +E GK+ Q L Q + +++ +++ EE +K AE L
Sbjct: 1327 EMLRKQVECLAEENGKL------VGHQNLHQKIQYVVRLKKENVRLAEETEKLRAENVFL 1380
Query: 457 KDDK 460
K+ K
Sbjct: 1381 KEKK 1384
Score = 35.0 bits (79), Expect = 0.19
Identities = 57/272 (20%), Positives = 114/272 (41%), Gaps = 17/272 (6%)
Query: 228 EKLKDDSKFS--EAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDM 285
+ L++ KF + + L + + E + NN ++++ +L E+D
Sbjct: 868 DNLQEIMKFEIDQLSRNLQNFKKENETLKSDLNNLMELLEAEKERNNKL---SLQFEEDK 924
Query: 286 EEAKEKFKQALSGILIQFEQIVA-VYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIH 344
E + ++ + L + + ++ A +K + + A K IS K + + +
Sbjct: 925 ENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEKVISSLEKSRDSDKKVV 984
Query: 345 NDELMGIRRE-----EEMEMSDDEIEEMTETKETEESALVSQAEAL----KEENDSLRWQ 395
D + I+ E+ E D +E+ + SALV + E+ K+E D L +
Sbjct: 985 ADLMNQIQELRTSVCEKTETIDTLKQELKDINCKYNSALVDREESRVLIKKQEVDILDLK 1044
Query: 396 LDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEK 455
+ R + L + + + ED + +QL +L +A + L QEE KKEA +++
Sbjct: 1045 -ETLRLRI-LSEDIERDMLCEDLAHATEQLNMLTEASKKHSGLLQSAQEELTKKEALIQE 1102
Query: 456 LKDDKLQVEKMLENLKEKESCASRLCASNQDS 487
L+ Q ++ +E K + + R DS
Sbjct: 1103 LQHKLNQKKEEVEQKKNEYNFKMRQLEHVMDS 1134
>gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 3 [Homo sapiens]
Length = 632
Score = 52.4 bits (124), Expect = 1e-06
Identities = 62/291 (21%), Positives = 133/291 (45%), Gaps = 30/291 (10%)
Query: 216 VHYSDHECSIVAEKLKDDSKFSEAVQTLLTWIERGEVNRRSANNFYSMIQSANS-HVRRL 274
+ Y + E +A +L+ + +++ L+ + E ++ AN S ++ + +
Sbjct: 156 LRYFEEESKDLAVRLQHSLQCKGELESALSAVIATE--KKKANQLSSCSKAHTEWELEQS 213
Query: 275 VNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWC 334
+ ++A + + + KE F+Q +Q E+ H ++ W QR +
Sbjct: 214 LQDQALLKAQLTQLKESFQQ------LQLERDECAEHIEGERARWH-----QRMS----- 257
Query: 335 KQAEEIRNIHNDELMGIRREEEMEMSDDEIE-EMTETKETEESALVSQAEA--LKEENDS 391
K ++EI + ++ +RR EE+E S +++ +M E E A+ S+ E L++E +
Sbjct: 258 KMSQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELER 317
Query: 392 LRWQLDAY---RNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKK 448
+ +L + + LL + Q + RE + +Q + LQ+ + ++Q L K Q ++
Sbjct: 318 VAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKLRQ-LAKPQSVFE- 375
Query: 449 KEAELEKLKDDKLQVEKMLENLKEKESCASRLCASNQDSEYPLEKTMNSSP 499
EL LQ+E+ ++ L+EK AS Q+ + + ++ + P
Sbjct: 376 ---ELNNENKSTLQLEQQVKELQEKLGEEHLEAASQQNQQLTAQLSLMALP 423
>gi|113425137 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 3 [Homo sapiens]
Length = 632
Score = 52.4 bits (124), Expect = 1e-06
Identities = 62/291 (21%), Positives = 133/291 (45%), Gaps = 30/291 (10%)
Query: 216 VHYSDHECSIVAEKLKDDSKFSEAVQTLLTWIERGEVNRRSANNFYSMIQSANS-HVRRL 274
+ Y + E +A +L+ + +++ L+ + E ++ AN S ++ + +
Sbjct: 156 LRYFEEESKDLAVRLQHSLQCKGELESALSAVIATE--KKKANQLSSCSKAHTEWELEQS 213
Query: 275 VNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWC 334
+ ++A + + + KE F+Q +Q E+ H ++ W QR +
Sbjct: 214 LQDQALLKAQLTQLKESFQQ------LQLERDECAEHIEGERARWH-----QRMS----- 257
Query: 335 KQAEEIRNIHNDELMGIRREEEMEMSDDEIE-EMTETKETEESALVSQAEA--LKEENDS 391
K ++EI + ++ +RR EE+E S +++ +M E E A+ S+ E L++E +
Sbjct: 258 KMSQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELER 317
Query: 392 LRWQLDAY---RNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKK 448
+ +L + + LL + Q + RE + +Q + LQ+ + ++Q L K Q ++
Sbjct: 318 VAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKLRQ-LAKPQSVFE- 375
Query: 449 KEAELEKLKDDKLQVEKMLENLKEKESCASRLCASNQDSEYPLEKTMNSSP 499
EL LQ+E+ ++ L+EK AS Q+ + + ++ + P
Sbjct: 376 ---ELNNENKSTLQLEQQVKELQEKLGEEHLEAASQQNQQLTAQLSLMALP 423
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 52.4 bits (124), Expect = 1e-06
Identities = 65/307 (21%), Positives = 124/307 (40%), Gaps = 38/307 (12%)
Query: 188 KQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSEAVQTLLTWI 247
+++ L RE++ RR EEER H HE ++LK + + W+
Sbjct: 415 REQQLRREQQLRREQEEER----------HEQKHEQERREQRLKREQEERR------DWL 458
Query: 248 ERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIV 307
+R E R + R E++ E +E+ +Q L + EQ
Sbjct: 459 KREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQL-----RREQEE 513
Query: 308 AVYHSASKQKAWDHFTKAQRKNISVWCKQAEE----IRNIHNDELMGIRREEEMEMSDDE 363
+Q+ + + R + +Q E ++ L RRE+ ++ +E
Sbjct: 514 RREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEE 573
Query: 364 IEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHR----EDDP 419
+ +E E Q +E+ + L +L R EVE L+QE+ + R E +
Sbjct: 574 RRDQLLKREEERR----QQRLKREQEERLEQRLK--REEVERLEQEERREQRLKREEPEE 627
Query: 420 NKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKESCASR 479
+ QQL ++ + QQ L + Q+E +++ K ++++ ++E+ L+ E+E
Sbjct: 628 ERRQQLLKSEEQEERRQQQLRREQQERREQRL---KREEEEERLEQRLKREHEEERREQE 684
Query: 480 LCASNQD 486
L Q+
Sbjct: 685 LAEEEQE 691
Score = 50.4 bits (119), Expect = 4e-06
Identities = 68/334 (20%), Positives = 130/334 (38%), Gaps = 22/334 (6%)
Query: 177 QARDDLYEWECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKF 236
+ R + E E +Q+ L RE++ RR+ EEER E+ + +
Sbjct: 285 ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQE----------------ERREQQERR 328
Query: 237 SEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDM--EEAKEKFKQ 294
+ + + R + RR + R E+ E+ + E+ + +Q
Sbjct: 329 EQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQ 388
Query: 295 ALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRRE 354
++ EQ + +++ + +R+ ++ E H E R +
Sbjct: 389 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLK 448
Query: 355 EEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVH 414
E E D ++ ET+ E+ Q + +EE RW E ++ + ++
Sbjct: 449 REQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLR 508
Query: 415 REDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKE 474
RE + +EQ+LK Q+ + +QQ L Q+ +++E E+L K + EK LE + +E
Sbjct: 509 REQEERREQRLK-RQEEEERLQQRLRSEQQLRREQEERREQLL--KREEEKRLEQ-ERRE 564
Query: 475 SCASRLCASNQDSEYPLEKTMNSSPIKSEREALL 508
R +D E+ +K E+E L
Sbjct: 565 QRLKREQEERRDQLLKREEERRQQRLKREQEERL 598
Score = 50.1 bits (118), Expect = 6e-06
Identities = 64/358 (17%), Positives = 151/358 (42%), Gaps = 57/358 (15%)
Query: 164 DKKDTGRLHVDFAQARDDLYEWECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHEC 223
D+K +L + + R LY Q L +E++ + EEE R + +
Sbjct: 871 DQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQ- 929
Query: 224 SIVAEKLKDDSKFSEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEK 283
+++ + + + LL ER + R+ Y + +L+ E+ EK
Sbjct: 930 ------YREEEQLQQEEEQLLR-EEREKRRRQERERQYRKDKKLQQKEEQLLGEEP--EK 980
Query: 284 DMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDH----------------FTKAQR 327
+ +EK + + + EQ++ +++ W+ + ++
Sbjct: 981 RRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREK 1040
Query: 328 KNISVWCKQAEEIRNIHNDE--LMG--------------IRREEEMEMSDDEI--EEMTE 369
+ + +Q E + +E L+G R+EEE++ ++++ EE +
Sbjct: 1041 RRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEK 1100
Query: 370 TKETEESALVSQAEALKEENDSL---------RWQLD-AYRNEVELLKQEQGKVHREDDP 419
+ E + E L++E + L R +L+ YR E E+ ++E+ + E +
Sbjct: 1101 RRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEK 1160
Query: 420 NKEQQLKLL---QQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKE 474
+ Q+L+ ++ LQ ++ LL+ ++E +++E E + ++++LQ +K + ++++
Sbjct: 1161 RRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDED 1218
Score = 48.1 bits (113), Expect = 2e-05
Identities = 71/309 (22%), Positives = 125/309 (40%), Gaps = 20/309 (6%)
Query: 170 RLHVDFAQARDDLYEWECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEK 229
RL Q RD+ W +Q REER R EEE+L+ + D E E
Sbjct: 160 RLEQRDRQRRDEEL-WRQRQEWQEREER---RAEEEQLQSCKGHETEEFPDEEQLRRREL 215
Query: 230 LKDDSKFSEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAK 289
L+ K E Q + + +L E+ +++++E +
Sbjct: 216 LELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEE 275
Query: 290 EKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHND-EL 348
E+ ++ L + Q +Q+ + +RK +Q EE R E
Sbjct: 276 EQLRKLERQELRRERQ-----EEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQ 330
Query: 349 MGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQ 408
RRE+++ +E E +E EE Q +E+ + R Q R E +L ++
Sbjct: 331 QEERREQQLRREQEERREQQLRREQEEERREQQLR--REQEEERREQ--QLRREQQLRRE 386
Query: 409 EQGKVHREDDPNKEQQLKLLQQALQGMQ----QHLLKVQEEYKKKEAELEKLKDDKLQVE 464
+Q + RE +EQQL+ QQ + Q Q L + Q+ +++E E + K ++ + E
Sbjct: 387 QQ--LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERRE 444
Query: 465 KMLENLKEK 473
+ L+ +E+
Sbjct: 445 QRLKREQEE 453
Score = 43.1 bits (100), Expect = 7e-04
Identities = 52/217 (23%), Positives = 97/217 (44%), Gaps = 22/217 (10%)
Query: 304 EQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEI-RNIHNDELMGIRREEEMEMSDD 362
EQ + +Q+ + K +++ W K+ EE R+ ++R++E E +
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Query: 363 ----EIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDD 418
E EE E +E E L + E +E+ L+ Q + R + L ++Q + RE +
Sbjct: 488 WLKLEEEERREQQERREQQLRREQEERREQR--LKRQEEEERLQQRLRSEQQ--LRREQE 543
Query: 419 PNKEQQLKLLQQ---ALQGMQQHLLKVQEEYK----KKEAELEKLKDDKLQVEKMLENLK 471
+EQ LK ++ + +Q L + QEE + K+E E + + + Q E++ + LK
Sbjct: 544 ERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLK 603
Query: 472 EKESCASRLCASNQDSEYPLEKTMNSSPIKSEREALL 508
+E RL + E ++ P + R+ LL
Sbjct: 604 REE--VERL----EQEERREQRLKREEPEEERRQQLL 634
Score = 43.1 bits (100), Expect = 7e-04
Identities = 52/210 (24%), Positives = 99/210 (47%), Gaps = 21/210 (10%)
Query: 281 HEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEI 340
HE++ E + K +Q ++ E+ + +++ + +R+ W K EE
Sbjct: 438 HEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER--WLKLEEEE 495
Query: 341 RNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYR 400
R + RRE+++ +E E ++ EE L + L+ E R Q + R
Sbjct: 496 RREQQE-----RREQQLRREQEERREQRLKRQEEEERL---QQRLRSEQQLRREQEE--R 545
Query: 401 NEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKK--EAELEKLKD 458
E +LLK+E+ K R + +EQ+LK Q+ + LLK +EE +++ + E E+ +
Sbjct: 546 RE-QLLKREEEK--RLEQERREQRLKREQEE---RRDQLLKREEERRQQRLKREQEERLE 599
Query: 459 DKLQVEKMLENLKEKESCASRLCASNQDSE 488
+L+ E+ +E L+++E RL + E
Sbjct: 600 QRLKREE-VERLEQEERREQRLKREEPEEE 628
Score = 43.1 bits (100), Expect = 7e-04
Identities = 68/330 (20%), Positives = 138/330 (41%), Gaps = 45/330 (13%)
Query: 177 QARDDLYEWECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKF 236
Q RD ++W+ +++ ER R+R+ RPP E + AE+ +
Sbjct: 763 QRRDFTWQWQAEEK----SERGRQRLSA---RPPLR------EQRERQLRAEERQ----- 804
Query: 237 SEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQAL 296
+ Q L E E RR +Q + E+A ++ E+
Sbjct: 805 -QREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEED--------- 854
Query: 297 SGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEE 356
G+ E+ + ++ W + +R+ +++ K A + + +L+ +EEE
Sbjct: 855 -GLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLL---QEEE 910
Query: 357 MEMSDDEIEEMTETKET-----EESALVSQAEALKEENDSLRWQLDA--YRNEVELLKQE 409
E+ +E E+ ++ EE + + L+EE + R Q YR + +L ++E
Sbjct: 911 EELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKE 970
Query: 410 QGKVHREDDPNKEQQLKLL---QQALQGMQQHLLKVQEEYKKK-EAELEKLKDDKLQ--V 463
+ + E + + Q+ + ++ LQ ++ LL+ + E +++ E E + K D+LQ
Sbjct: 971 EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEE 1030
Query: 464 EKMLENLKEKESCASRLCASNQDSEYPLEK 493
E++L +EK R ++ E E+
Sbjct: 1031 EQLLREEREKRRLQERERQYREEEELQQEE 1060
Score = 41.2 bits (95), Expect = 0.003
Identities = 64/365 (17%), Positives = 148/365 (40%), Gaps = 26/365 (7%)
Query: 157 IRLGSSTDKKDTGRLHVDFAQARDDLYEWECKQRMLAREERHRRRMEEERLRPPSPPPVV 216
+R +K+ R D ++ EW ++ +L +EE + E +R R +
Sbjct: 218 LRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQR-----ELQ 272
Query: 217 HYSDHECSIVAEKLKDDSKFSEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVN 276
+ + ++L+ + + E Q L ++ R+ + R
Sbjct: 273 EEEEQLRKLERQELRRERQEEEQQQQRLR--REQQLRRKQEEERREQQEERREQQERREQ 330
Query: 277 EKAAHEKDM-EEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCK 335
++ E+ + E +E+ +Q L + + + +++ + Q+ +
Sbjct: 331 QEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLR 390
Query: 336 QAEEIR---NIHNDELM----GIRREE----EMEMSDDEIEEMTETKETEESALVSQAEA 384
+ +++R + ++ + +RRE+ E ++ ++ EE E K +E
Sbjct: 391 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKRE 450
Query: 385 LKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQ----QHLL 440
+E D L+ + + R+E E KQ+ + E+ +E+ LKL ++ + Q Q L
Sbjct: 451 QEERRDWLKREEETERHEQERRKQQLKRDQEEE--RRERWLKLEEEERREQQERREQQLR 508
Query: 441 KVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKESCASRLCASNQDSEYPLEKTMNSSPI 500
+ QEE +++ + ++ ++++LQ E +E R ++ E LE+ +
Sbjct: 509 REQEERREQRLKRQE-EEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRL 567
Query: 501 KSERE 505
K E+E
Sbjct: 568 KREQE 572
Score = 40.8 bits (94), Expect = 0.003
Identities = 50/294 (17%), Positives = 124/294 (42%), Gaps = 45/294 (15%)
Query: 184 EWECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSEAVQTL 243
E + ++ L REER +RR +E + + +++ + + + L
Sbjct: 1115 ELQQEEEQLLREEREKRRRQE---------------------LERQYREEEEVQQEEEQL 1153
Query: 244 LTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQF 303
L E E RR Q R + E+ + E +EK +Q +
Sbjct: 1154 LR--EEPEKRRR---------QELERQYREEEELQQEEEQLLREEQEKRRQERERQYREE 1202
Query: 304 EQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEM--EMSD 361
E++ +QK + +++ W + E+ + ++++ RE E ++ D
Sbjct: 1203 EEL-------QRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLED 1255
Query: 362 DEIEEMTETKETEESALVSQAEALKEENDSLRW-QLDAYRNEVELLKQEQGKVHREDDPN 420
++ + ++ + L+ + + E + RW Q D + E E L++E+ K + D
Sbjct: 1256 SQLRDRQSQQDLQH--LLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRK 1313
Query: 421 KEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKE 474
+++ +LL++ + ++ + +++++E L++ ++ L+ ++ +E+E
Sbjct: 1314 SQEEKQLLREEREEKRRR-QETDRKFREEEQLLQEREEQPLRRQERDRKFREEE 1366
Score = 40.8 bits (94), Expect = 0.003
Identities = 54/288 (18%), Positives = 120/288 (41%), Gaps = 30/288 (10%)
Query: 186 ECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSEAVQTLLT 245
E +++ L R+ER R+ +EEE P + + E + ++ D KF E Q L
Sbjct: 1630 EREEQQLHRQERDRKFLEEE--------PQLRRQEREQQLRHDR---DRKFREEEQLL-- 1676
Query: 246 WIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQ 305
+ GE + + +RR E+ K ++E ++ +Q L + EQ
Sbjct: 1677 --QEGEEQQLRRQERDRKFREEEQQLRRQERER----KFLQEEQQLRRQELERKFREEEQ 1730
Query: 306 I--VAVYHSASKQKAWDHFTKAQR---KNISVWCKQAEEIRNIHNDELMGIRREEEMEMS 360
+ +Q+ + + ++ + ++ E R +E + REE+ S
Sbjct: 1731 LRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRS 1790
Query: 361 DDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPN 420
+ + E ++ + Q ++ + RW+ +++L +QEQ ++ +E D
Sbjct: 1791 QESDRKFREEEQLRQEREEQQLRP-QQRDGKYRWE----EEQLQLEEQEQ-RLRQERDRQ 1844
Query: 421 KEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLE 468
+ + Q ++ L +EE K+++ KL+++ ++ ++ E
Sbjct: 1845 YRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEE 1892
Score = 40.0 bits (92), Expect = 0.006
Identities = 60/308 (19%), Positives = 128/308 (41%), Gaps = 27/308 (8%)
Query: 186 ECKQRMLAREERHRR----RMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSEAVQ 241
E +Q+ L RE++ RR + EEE R H + +AE+ ++ ++ E ++
Sbjct: 641 ERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQAR--ERIK 698
Query: 242 TLLT---WIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDME---------EAK 289
+ + W E + R + YS + RR E+ ++ E +
Sbjct: 699 SRIPKWQWQLESEADARQSK-VYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQ 757
Query: 290 EKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELM 349
++ ++ Q++ + A + + + + +Q E R + +E
Sbjct: 758 QQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEK 817
Query: 350 GIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQE 409
RR + E +E+ +E E+ +A+ L+EE D L+ + R++ + Q+
Sbjct: 818 EQRRRQRRERE----KELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQK 873
Query: 410 QGKVHREDDPNKEQQL---KLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKM 466
E+ + L LQ+ L+ QQ L + +EE +++E E + ++ + Q +
Sbjct: 874 WRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREE 933
Query: 467 LENLKEKE 474
E L+++E
Sbjct: 934 -EQLQQEE 940
Score = 40.0 bits (92), Expect = 0.006
Identities = 57/318 (17%), Positives = 129/318 (40%), Gaps = 42/318 (13%)
Query: 194 REERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLK-------------------DDS 234
R+ERHR+ EEE+L +H + + + E+ + +
Sbjct: 1456 RQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPER 1515
Query: 235 KFSEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDM---EEAKEK 291
KF E Q L R + R+ + + RR ++ E++ E +++
Sbjct: 1516 KFLEEEQQL----HRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQ 1571
Query: 292 FKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGI 351
+ + E+ V ++K + + +R+ +Q + + +++L+
Sbjct: 1572 LSRQERDRKFRLEE-QKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQE 1630
Query: 352 RREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQG 411
R E+++ + + + + E + Q ++ QL E +L +QE+
Sbjct: 1631 REEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERD 1690
Query: 412 KVHREDDP---NKEQQLKLLQQALQGMQQHLLKV--QEEYKKKEAELEKLK--------- 457
+ RE++ +E++ K LQ+ Q +Q L + +EE ++E E E+L+
Sbjct: 1691 RKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKIL 1750
Query: 458 -DDKLQVEKMLENLKEKE 474
+++L+ E+ + L+ +E
Sbjct: 1751 EEEQLRPEREEQQLRRQE 1768
Score = 39.7 bits (91), Expect = 0.008
Identities = 71/339 (20%), Positives = 139/339 (41%), Gaps = 46/339 (13%)
Query: 184 EWECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSEAVQTL 243
E + ++ L REE+ +RR E ER Y + E + +K K + E ++
Sbjct: 1175 ELQQEEEQLLREEQEKRRQERER----------QYREEE-ELQRQKRKQRYR-DEDQRSD 1222
Query: 244 LTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQF 303
L W + E + +A ++ + + NE+ +D + + +Q L +L +
Sbjct: 1223 LKW--QWEPEKENA------VRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQ 1274
Query: 304 EQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDE 363
++ Q+ HF + ++ K+A+ +E +R E E + E
Sbjct: 1275 QERDREQERRRWQQRDRHFPEEEQLEREEQ-KEAKRRDRKSQEEKQLLREEREEKRRRQE 1333
Query: 364 IEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDP---- 419
T+ K EE L+ + +EE R + D E EL QEQG+ E++
Sbjct: 1334 ----TDRKFREEEQLLQE----REEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR 1385
Query: 420 --------NKEQQLKLLQQALQGMQQHLLKVQEEYKK--KEAELEKLKDDKLQV---EKM 466
+EQQL+ ++ Q Q K +EE ++ ++ K ++++ QV E+
Sbjct: 1386 QERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERE 1445
Query: 467 LENLKEKESCASRLCASNQDSEYPLEKTMNSSPIKSERE 505
+ L+E++ ++ E L++ + ER+
Sbjct: 1446 RKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERD 1484
Score = 38.5 bits (88), Expect = 0.017
Identities = 41/178 (23%), Positives = 80/178 (44%), Gaps = 16/178 (8%)
Query: 324 KAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAE 383
K +R+ C++ EE++ L R + + + + E E ++ EE L + E
Sbjct: 1100 KRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPE 1159
Query: 384 A---------LKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQG 434
+EE + + + R E E +QE+ + +RE++ + Q+ K Q+
Sbjct: 1160 KRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRK--QRYRDE 1217
Query: 435 MQQHLLKVQEEYKKKEAELEKLKDDKLQVE-KMLENLKEKESCASRLCASNQDSEYPL 491
Q+ LK Q E +K+ A ++D+K+ + + E ++ E R S QD ++ L
Sbjct: 1218 DQRSDLKWQWEPEKENA----VRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLL 1271
Score = 33.1 bits (74), Expect = 0.72
Identities = 62/311 (19%), Positives = 119/311 (38%), Gaps = 54/311 (17%)
Query: 177 QARDDLYEWECKQRMLAREERHRR---RMEEERLRPPSPPPVVHYSDHECSIVAEKLKDD 233
+ + +E E +++ L RE+ RR + EEE R HE E+ K
Sbjct: 432 ERHEQKHEQERREQRLKREQEERRDWLKREEETER------------HE----QERRKQQ 475
Query: 234 SKFSEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFK 293
K + + W++ E RR + +RR E+ +E +E+ +
Sbjct: 476 LKRDQEEERRERWLKLEEEERREQQ------ERREQQLRREQEERREQRLKRQEEEERLQ 529
Query: 294 QALSGI-------------LIQFEQIVAVYHSASKQKAW-------DHFTKAQRKNISVW 333
Q L L++ E+ + +Q+ D K + +
Sbjct: 530 QRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQR 589
Query: 334 CKQAEEIR---NIHNDELMGI----RREEEMEMSDDEIEEMTETKETEESALVSQAEALK 386
K+ +E R + +E+ + RRE+ ++ + E E + ++EE Q + L+
Sbjct: 590 LKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ-LR 648
Query: 387 EENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEY 446
E R Q E E L+Q + H E+ +E + +QA + ++ + K Q +
Sbjct: 649 REQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQL 708
Query: 447 KKKEAELEKLK 457
+ EA+ + K
Sbjct: 709 -ESEADARQSK 718
Score = 33.1 bits (74), Expect = 0.72
Identities = 41/184 (22%), Positives = 75/184 (40%), Gaps = 18/184 (9%)
Query: 186 ECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSEAVQTLLT 245
E +Q L R+ER+R+ +EEE+LRP + + D KF E Q
Sbjct: 1734 ETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQER-----------DRKFREEEQLRQ- 1781
Query: 246 WIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQ 305
ER E RS + + R + ++D + E+ + L + Q
Sbjct: 1782 --EREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQ 1839
Query: 306 IVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELM--GIRREEEMEMSDDE 363
+ A +Q A K++R+ +W ++ ++ R +L IRR+++ E +
Sbjct: 1840 ERDRQYRAEEQFATQE--KSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQ 1897
Query: 364 IEEM 367
+ E+
Sbjct: 1898 VGEI 1901
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 52.4 bits (124), Expect = 1e-06
Identities = 81/404 (20%), Positives = 165/404 (40%), Gaps = 28/404 (6%)
Query: 108 ENGTEQIIVEVFEQCGEIIAIRKSKKNFCHIRFAEEYMVDKALYLSGYRIRLGSSTDKKD 167
EN ++ +I E+ +II + K +I +E +++ L + DK D
Sbjct: 702 ENESDSLIQELETSNKKIITQNQRIKELINIIDQKEDTINEFQNLKSHMENTFKCNDKAD 761
Query: 168 TGRLHVDFAQARDDLYEWECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVA 227
T L ++ ++ E + ER +R+ E L+ PP S H S +
Sbjct: 762 TSSLIINNKLICNETVEVPKDSKSKICSER--KRVNENELQQDEPP-AKKGSIHVSSAIT 818
Query: 228 EKLKDDSKFSEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEE 287
E D K SE V+ + IE V + + + + + + ++ EKA K +
Sbjct: 819 E----DQKKSEEVRPNIAEIEDIRVLQENNEGLRAFLLTIENELKNEKEEKAELNKQIVH 874
Query: 288 AKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQ-RKNISVWCKQAEEIRNIHND 346
+++ + L +++ + + A H K++ ++ K + EI
Sbjct: 875 FQQELSLSEKKNLTLSKEVQQIQSNYDIAIAELHVQKSKNQEQEEKIMKLSNEIETATRS 934
Query: 347 ELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALK--EENDSLRWQLDAYRNEVE 404
+ + + M DE+ + + L++ + EE++ QLD N+
Sbjct: 935 ITNNVSQIKLMHTKIDELRTLDSVSQISNIDLLNLRDLSNGSEEDNLPNTQLDLLGNDY- 993
Query: 405 LLKQEQGKVHREDDPNKE-----------QQLKLLQQALQGMQQHLLKVQEEYKKKEAEL 453
L +Q K +R +PN+E ++ K + +A + +++++ +K +AE+
Sbjct: 994 -LVSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEV 1052
Query: 454 EKLKDDKLQV-EKMLEN----LKEKESCASRLCASNQDSEYPLE 492
+ KD+ ++ EK +N LKEKE+ +L Q+ L+
Sbjct: 1053 KGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLD 1096
Score = 41.2 bits (95), Expect = 0.003
Identities = 55/285 (19%), Positives = 128/285 (44%), Gaps = 18/285 (6%)
Query: 200 RRMEEERLRPPSPPPVVHYSDH----ECSIVAEKLKDDSKFSEAVQTLLTWIERGEVNRR 255
++++E R++ P+ H S EC E +K SK S ++ L IE+ + +
Sbjct: 997 KQVKEYRIQEPNRENSFHSSIEAIWEECK---EIVKASSKKSHQIEELEQQIEKLQAEVK 1053
Query: 256 SANNFYSMI-QSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSAS 314
+ + + + + + L+ EK E +++ KE+ ++ + +Q + +V + S
Sbjct: 1054 GYKDENNRLKEKEHKNQDDLLKEK---ETLIQQLKEELQEKNVTLDVQIQHVVEGKRALS 1110
Query: 315 KQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEE-----MEMSDDEIEEMTE 369
+ KA+ K + + +++ H+ +L E+E +E + E +E +
Sbjct: 1111 ELTQGVTCYKAKIKELET-ILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQ 1169
Query: 370 TKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQ 429
L + LKEE L L ++ ++L K+E+ + +R++ +++L
Sbjct: 1170 DSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQL-KEEEEETNRQETEKLKEELSASS 1228
Query: 430 QALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKE 474
Q ++ L + +E+Y + +L K QV+K + +++++
Sbjct: 1229 ARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDED 1273
Score = 32.0 bits (71), Expect = 1.6
Identities = 35/175 (20%), Positives = 79/175 (45%), Gaps = 14/175 (8%)
Query: 338 EEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLD 397
+E + + D+L+ +E ++ +E++E T + + +V AL E L +
Sbjct: 1063 KEKEHKNQDDLLK-EKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSE----LTQGVT 1117
Query: 398 AYRNEVELLKQ--EQGKVH-------REDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKK 448
Y+ +++ L+ E KV +D KE + L++ L+ Q+HL + K
Sbjct: 1118 CYKAKIKELETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKD 1177
Query: 449 KEAELEKLKDDKLQVEKMLENLKEKESCASRLCASNQDSEYPLEKTMNSSPIKSE 503
+ KLK++ Q+ L+++K +N+ L++ +++S +++
Sbjct: 1178 LNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQ 1232
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 52.4 bits (124), Expect = 1e-06
Identities = 83/413 (20%), Positives = 167/413 (40%), Gaps = 72/413 (17%)
Query: 108 ENGTEQIIVEVFEQCGEIIAIRKSKKNFCHIRFAEEYMVDKALYLSGYRIRLGSSTDKKD 167
E ++ +E+ + + + K+K NF + E + + + RL + +
Sbjct: 1222 EKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQK 1281
Query: 168 TGRLHVDFAQARDDLYEWEC--------KQRMLAREERHRRRMEEERLRPPSPPPVVHYS 219
RLH + + L E + KQ + E +R++EEE + + +
Sbjct: 1282 A-RLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSA 1340
Query: 220 DHECSIVAEKLKDDSK--------FSEAVQTLLTW--------IERGEVNRRSANNFYSM 263
H+C ++ E+ +++ + S+A + W I+R E +
Sbjct: 1341 RHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1400
Query: 264 IQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQI-VAVYHSASKQKAWDHF 322
+Q A HV VN K A +E+ K++ + + ++I E+ A KQ+ +D
Sbjct: 1401 LQDAEEHV-EAVNSKCA---SLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFD-- 1454
Query: 323 TKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIE----EMTETKETEESAL 378
K ++ W ++ EE + E+E S E E+ + K E +L
Sbjct: 1455 -----KVLAEWKQKYEE-------------TQAELEASQKESRSLSTELFKVKNAYEESL 1496
Query: 379 VSQAEALKEENDSLRWQLDAYRNEVE---LLKQEQGKVHREDDPNKEQQLKLLQQA---L 432
E LK EN +L+ ++ ++ E KV ++ D K + L++A L
Sbjct: 1497 -DHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASL 1555
Query: 433 QGMQQHLLKVQEEYK-----------KKEAELEKLKDDKLQVEKMLENLKEKE 474
+ + +L++Q E +K+ EL++LK + L+V + +++ + E
Sbjct: 1556 EHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAE 1608
Score = 41.6 bits (96), Expect = 0.002
Identities = 50/262 (19%), Positives = 115/262 (43%), Gaps = 25/262 (9%)
Query: 228 EKLKDDSKFSEAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEE 287
E K ++K E + ++T ++ + + A +L+ K E ++E
Sbjct: 866 ELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAKIKE 925
Query: 288 AKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDE 347
E+ + E+ + +A K+K D ++ ++ + A+ + H E
Sbjct: 926 VTERAED---------EEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 976
Query: 348 LMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSL------RWQLDAYRN 401
EEM D+ I ++T+ K+ + A + L+ E D + + +L+ +
Sbjct: 977 NKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVD 1036
Query: 402 EVELLKQEQGKVHREDDPNK---EQQLKLLQQALQGMQQHLLKVQEEYKKKEAELE---- 454
++E +++ K+ + + K E LKL Q++ + ++ E+ KKKE E+
Sbjct: 1037 DLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQG 1096
Query: 455 KLKDDK---LQVEKMLENLKEK 473
K++D++ +Q++K ++ L+ +
Sbjct: 1097 KIEDEQALAIQLQKKIKELQAR 1118
Score = 35.0 bits (79), Expect = 0.19
Identities = 31/129 (24%), Positives = 57/129 (44%), Gaps = 5/129 (3%)
Query: 352 RREEEMEMSD--DEIEEMTETKETEESALVSQAEALKE---ENDSLRWQLDAYRNEVELL 406
R + E + SD E+EE++E E A +Q E K+ E +R L+ + E
Sbjct: 1133 RAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEAT 1192
Query: 407 KQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKM 466
K H + +Q+ LQ+ Q +++ +++ E + +E + K EKM
Sbjct: 1193 AAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKM 1252
Query: 467 LENLKEKES 475
L+++ S
Sbjct: 1253 CRTLEDQLS 1261
Score = 30.8 bits (68), Expect = 3.6
Identities = 29/142 (20%), Positives = 66/142 (46%), Gaps = 22/142 (15%)
Query: 337 AEEIRNIH--NDELMGIRREEEMEMS------DDEIEEMTETKETEESALVS---QAEAL 385
+E ++ +H N L+ +++ E ++S +D ++E +E + A+ AE L
Sbjct: 1714 SERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEEL 1773
Query: 386 KEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEE 445
K+E D+ +N + +K Q ++ + Q AL+G ++ + K++
Sbjct: 1774 KKEQDTSAHLERMKKNMEQTVKDLQLRLDEAE-----------QLALKGGKKQIQKLEAR 1822
Query: 446 YKKKEAELEKLKDDKLQVEKML 467
++ E+E+E + ++ K L
Sbjct: 1823 VRELESEVESEQKHNVEAVKGL 1844
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 52.0 bits (123), Expect = 1e-06
Identities = 69/322 (21%), Positives = 132/322 (40%), Gaps = 44/322 (13%)
Query: 184 EWECKQRMLAREERHRR------RMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFS 237
E E K++ + E+RH + R+ +R R ++ +++ K +
Sbjct: 1553 EGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEK----------------KRAQEERKLA 1596
Query: 238 EAVQTLLTWIERGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALS 297
+ + L + R Y I + + + + A E+ + + EK Q
Sbjct: 1597 QEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAE 1656
Query: 298 GILIQFEQIVAVYHSASKQK---AWDHFTKAQRKNISVWCKQAEEI----RNIHNDELMG 350
+ + +++ + ++++ A A+ KNI ++ EE+ +N+ E
Sbjct: 1657 KLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILA--QKVEELPQREQNLDWQEKEL 1714
Query: 351 IRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLD-------AYRNEV 403
+ EE+E +E+ E EE LV + + L EE ++L WQ + E
Sbjct: 1715 AQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEE 1774
Query: 404 ELLKQEQGKV--HREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKL 461
ELL QE+ K+ H+E P +E++L ++ L + L + +E + EL K K
Sbjct: 1775 ELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILY 1834
Query: 462 QVEKMLENLK----EKESCASR 479
Q + + + K EKE A R
Sbjct: 1835 QKKNLAQEKKNLAQEKEKLAQR 1856
Score = 49.7 bits (117), Expect = 7e-06
Identities = 68/329 (20%), Positives = 145/329 (44%), Gaps = 32/329 (9%)
Query: 190 RMLAREERHRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLK-DDSKFSEAVQTLLTWIE 248
+ L + R R++ +E ++ + + SI KL + FSE +
Sbjct: 2078 KALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSE---------K 2128
Query: 249 RGEVNRRSANNFYSMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVA 308
R E+ + + AN +RR++N+ E+ M E + K + S +++ E+
Sbjct: 2129 RSELTKDEKKLARKQRKLANK-MRRMINK----EEKMTEEESKLARKHSEVILDDEEEGG 2183
Query: 309 VYHSAS---KQKAWDHFTKAQR--KNISVWCKQAEEIRNIHN--DELMGIRREEEME--M 359
+ ++ W +A+R K + Q +E+ + + +E+ + E E + +
Sbjct: 2184 IEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESL 2243
Query: 360 SDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGK--VHRED 417
S +E EE E +E EE + + E KEE + Q++ E + K+E+ K V ++
Sbjct: 2244 SSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKE 2303
Query: 418 DPNKEQQLKLLQQALQGM-----QQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKE 472
+ +E++ + ++ + + ++ ++EE +++ L+K K KLQ E+ ++L+
Sbjct: 2304 EVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQ-EQRRKSLRG 2362
Query: 473 KESCASRLCASNQDSEYPLEKTMNSSPIK 501
+E S L + + SP+K
Sbjct: 2363 RERVLSILRGVPHGKGRAIRLGVLKSPLK 2391
Score = 48.1 bits (113), Expect = 2e-05
Identities = 57/250 (22%), Positives = 109/250 (43%), Gaps = 28/250 (11%)
Query: 271 VRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQ---KAWDHFTKAQ- 326
V ++ E E+DM E E+ ++ Q ++V + + S Q KAWD + +
Sbjct: 1413 VGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHG 1472
Query: 327 --RKNISVWCKQAEEIRNIHNDELMG-----IRREEEMEMSDDEI---------EEMTET 370
RK+ W K+ E R + +E + + EEEM D ++ E M +
Sbjct: 1473 ETRKSWKAW-KEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSS 1531
Query: 371 KETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGK---VHRE----DDPNKEQ 423
K E+ + L+EE + + E + QE+ K +HR+ + ++
Sbjct: 1532 KSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQE 1591
Query: 424 QLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKESCASRLCAS 483
+ KL Q+ + Q+ QEE K +A ++ +DD+ + + +++E+ A R
Sbjct: 1592 ERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKL 1651
Query: 484 NQDSEYPLEK 493
+Q++E +K
Sbjct: 1652 SQEAEKLAQK 1661
Score = 42.0 bits (97), Expect = 0.002
Identities = 60/319 (18%), Positives = 127/319 (39%), Gaps = 25/319 (7%)
Query: 184 EWECKQRMLAREER-----HRRRMEEERLRPPSPPPVVHYSDHECSIVAEKLKDDSKFSE 238
EWE +R+L EE+ + EEE L+ + ++++ K K+ E
Sbjct: 1484 EWE--KRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDE 1541
Query: 239 AVQTLLTWIER-GEVNRRSANNFYSMIQSANSHVR------RLVNEKAAHEKDMEEAKEK 291
TL + R GE + IQ + R R ++A E+ + + +EK
Sbjct: 1542 EEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEK 1601
Query: 292 FKQALSGILIQFEQIVAVYHSASKQ-----KAWDHFTKAQRKNISVWCKQAEEIRNIHND 346
Q + + ++ Y ++ +A F + + K ++E +
Sbjct: 1602 LAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQK 1661
Query: 347 ELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELL 406
++ E++ ++++ + ++ L + E L + +L WQ E+E L
Sbjct: 1662 RKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEEL 1721
Query: 407 KQEQGKVH-REDDPNKE-----QQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDK 460
+ + ++ +E++ N+E ++ K L + + + K+ EE K E E L +K
Sbjct: 1722 EWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEK 1781
Query: 461 LQVEKMLENLKEKESCASR 479
++ + E + E+E R
Sbjct: 1782 EKLAQHKEKMPEEEERLGR 1800
Score = 39.3 bits (90), Expect = 0.010
Identities = 42/197 (21%), Positives = 90/197 (45%), Gaps = 13/197 (6%)
Query: 315 KQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETE 374
++K + +K RK+ V EE I +E++ + + + + + + K +
Sbjct: 2157 EEKMTEEESKLARKHSEVILDDEEE-GGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSS 2215
Query: 375 ESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQAL-- 432
+ V E EE +SL +L+ + E L E+ + E++ +E++++ ++
Sbjct: 2216 QVDEVESEEHFSEEMESLLDELE----KQESLSSEEEEEREEEEEREEEEVREEEEERKE 2271
Query: 433 --QGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKESCASRLCASNQDSEYP 490
+G ++ + K +EE KKK+ EK K++ + E++ E +++E + S D E
Sbjct: 2272 EEEGEEKQVEKEEEEKKKKKK--EKKKEEVQEKEEVFE--EKEEIMSEEETESLSDEEEE 2327
Query: 491 LEKTMNSSPIKSEREAL 507
E + E+E L
Sbjct: 2328 EESCSLEEEVDREKEIL 2344
Score = 35.4 bits (80), Expect = 0.15
Identities = 51/230 (22%), Positives = 103/230 (44%), Gaps = 26/230 (11%)
Query: 265 QSANSHVRRLVNEKAAHEKDMEEA--KEKFKQALSGILIQFEQIVAVYHSA---SKQKAW 319
Q+ + + L E E DMEE KE+ G L++ ++ +A A ++K
Sbjct: 1705 QNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLS 1764
Query: 320 DHFTK-AQRKNISVWCKQA---EEIRNIHNDELMGIRREEEMEMSD----------DEIE 365
+ TK AQ + + + K+ + + +E +G +RE+ +E + +E
Sbjct: 1765 EEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSME 1824
Query: 366 EMTETKET--EESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQ 423
E+T+ K ++ L + + L +E + L A R E L +E+ ++ +
Sbjct: 1825 ELTKNKMILYQKKNLAQEKKNLAQEKEKL-----AQRKENLLYNKERLTHSKKQLVQVKN 1879
Query: 424 QLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEK 473
+L + + L +++ L + +E KK+ +L + + +QVE L +EK
Sbjct: 1880 KLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEK 1929
Score = 34.7 bits (78), Expect = 0.25
Identities = 40/219 (18%), Positives = 102/219 (46%), Gaps = 23/219 (10%)
Query: 274 LVNEK---AAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTKAQRKNI 330
L+ EK A H++ M E +E+ + ++ + ++ A K++ W + + KN
Sbjct: 1777 LIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKL------AQKRERWINSMEELTKNK 1830
Query: 331 SVWCKQ---AEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKE 387
+ ++ A+E +N+ ++ +R+E + + + + + ++ L + L +
Sbjct: 1831 MILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQ 1890
Query: 388 ENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQAL---------QGMQ-- 436
+ L + + + E L + + K+ + +D ++Q KL Q+ + QG +
Sbjct: 1891 VEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRL 1950
Query: 437 QHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKES 475
+ L + +E K E+++L ++K+++ + E L + E+
Sbjct: 1951 RGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGET 1989
>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 479
Score = 52.0 bits (123), Expect = 1e-06
Identities = 52/216 (24%), Positives = 98/216 (45%), Gaps = 14/216 (6%)
Query: 262 SMIQSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSA--SKQKAW 319
++I ++ LV +K +K ++L + Q + +A A SK +
Sbjct: 103 AIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQL 162
Query: 320 DHFTKAQRKNISVWCKQAE-EIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESAL 378
T RK + +Q + E+ N L+ R+EE + ++ + E E +E L
Sbjct: 163 QDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERL 222
Query: 379 VSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQH 438
Q E L E+ + LR Q E L++++ ++H +++ EQ+ +L +Q + +Q
Sbjct: 223 CEQEERLCEQEERLREQ-------EERLREQEERLHEQEERLCEQEERLCEQEERLCEQE 275
Query: 439 LLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKE 474
L QE + E+EKL + + + E+ E L E+E
Sbjct: 276 KLPGQERLLE---EVEKLLEQERRQEEQ-ERLLERE 307
Score = 35.8 bits (81), Expect = 0.11
Identities = 36/150 (24%), Positives = 73/150 (48%), Gaps = 8/150 (5%)
Query: 362 DEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNK 421
+++++ T E ++ Q +A E N L L R E L +QE+ ++H +++
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQML--SLLNRRQEERLREQEE-RLHEQEERLH 216
Query: 422 EQQLKLLQQALQ-GMQQHLLKVQEEYKKKEAELEKLKDDKL--QVEKMLENLKEKESCAS 478
EQ+ +L +Q + Q+ L+ QEE +++ E ++++L Q E++ E +E+ C
Sbjct: 217 EQEERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEERLCE--QEERLCEQ 274
Query: 479 RLCASNQDSEYPLEKTMNSSPIKSEREALL 508
+ +EK + + E+E LL
Sbjct: 275 EKLPGQERLLEEVEKLLEQERRQEEQERLL 304
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,518,548
Number of Sequences: 37866
Number of extensions: 1309854
Number of successful extensions: 16376
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 287
Number of HSP's successfully gapped in prelim test: 1037
Number of HSP's that attempted gapping in prelim test: 9358
Number of HSP's gapped (non-prelim): 5162
length of query: 581
length of database: 18,247,518
effective HSP length: 108
effective length of query: 473
effective length of database: 14,157,990
effective search space: 6696729270
effective search space used: 6696729270
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.