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Search of human proteins with 32455252
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32455252 phosphoinositide-3-kinase, regulatory subunit 1
(alpha) isoform 2 [Homo sapiens]
(454 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32455252 phosphoinositide-3-kinase, regulatory subunit 1 (alp... 931 0.0
gi|32455248 phosphoinositide-3-kinase, regulatory subunit 1 (alp... 858 0.0
gi|32455250 phosphoinositide-3-kinase, regulatory subunit 1 (alp... 853 0.0
gi|166795247 phosphoinositide-3-kinase, regulatory subunit 3 (p5... 723 0.0
gi|166795245 phosphoinositide-3-kinase, regulatory subunit 3 (p5... 723 0.0
gi|4826908 phosphoinositide-3-kinase, regulatory subunit 2 (beta... 667 0.0
gi|120432042 vav 3 guanine nucleotide exchange factor isoform 2 ... 59 9e-09
gi|120432044 vav 3 guanine nucleotide exchange factor isoform 1 ... 59 9e-09
gi|4507263 suppressor of cytokine signaling-2 [Homo sapiens] 58 2e-08
gi|7108367 vav 1 guanine nucleotide exchange factor [Homo sapiens] 56 6e-08
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 56 8e-08
gi|21450785 suppressor of cytokine signaling 6 [Homo sapiens] 56 8e-08
gi|117320537 phospholipase C, gamma 2 [Homo sapiens] 55 1e-07
gi|4557377 Bruton agammaglobulinemia tyrosine kinase [Homo sapiens] 55 1e-07
gi|153266778 arg tyrosine kinase isoform c [Homo sapiens] 54 3e-07
gi|6382062 arg tyrosine kinase isoform b [Homo sapiens] 54 3e-07
gi|209862778 arg tyrosine kinase isoform e [Homo sapiens] 54 3e-07
gi|209862772 arg tyrosine kinase isoform d [Homo sapiens] 54 3e-07
gi|153266757 arg tyrosine kinase isoform a [Homo sapiens] 54 3e-07
gi|21450844 megakaryocyte-associated tyrosine kinase isoform c [... 54 4e-07
gi|21450842 megakaryocyte-associated tyrosine kinase isoform b [... 54 4e-07
gi|21450846 megakaryocyte-associated tyrosine kinase isoform a [... 54 4e-07
gi|197304715 vav 2 guanine nucleotide exchange factor isoform 1 ... 54 4e-07
gi|40549448 vav 2 guanine nucleotide exchange factor isoform 2 [... 54 4e-07
gi|4502435 BMX non-receptor tyrosine kinase [Homo sapiens] 52 8e-07
gi|42544182 BMX non-receptor tyrosine kinase [Homo sapiens] 52 8e-07
gi|5174647 PTK6 protein tyrosine kinase 6 [Homo sapiens] 52 8e-07
gi|148596974 TXK tyrosine kinase [Homo sapiens] 52 8e-07
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof... 52 8e-07
gi|120953243 leucine-rich repeats and IQ motif containing 1 isof... 52 8e-07
>gi|32455252 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
isoform 2 [Homo sapiens]
Length = 454
Score = 931 bits (2407), Expect = 0.0
Identities = 454/454 (100%), Positives = 454/454 (100%)
Query: 1 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVANNGMNNNMSLQD 60
MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVANNGMNNNMSLQD
Sbjct: 1 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVANNGMNNNMSLQD 60
Query: 61 AEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKY 120
AEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKY
Sbjct: 61 AEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKY 120
Query: 121 GFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLH 180
GFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLH
Sbjct: 121 GFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLH 180
Query: 181 EYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIE 240
EYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIE
Sbjct: 181 EYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIE 240
Query: 241 KFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDL 300
KFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDL
Sbjct: 241 KFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDL 300
Query: 301 IQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSN 360
IQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSN
Sbjct: 301 IQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSN 360
Query: 361 RNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSS 420
RNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSS
Sbjct: 361 RNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSS 420
Query: 421 LKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR 454
LKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
Sbjct: 421 LKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR 454
>gi|32455248 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
isoform 1 [Homo sapiens]
Length = 724
Score = 858 bits (2216), Expect = 0.0
Identities = 420/420 (100%), Positives = 420/420 (100%)
Query: 35 PALPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKM 94
PALPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKM
Sbjct: 305 PALPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKM 364
Query: 95 HGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKL 154
HGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKL
Sbjct: 365 HGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKL 424
Query: 155 LYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAI 214
LYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAI
Sbjct: 425 LYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAI 484
Query: 215 EAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRR 274
EAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRR
Sbjct: 485 EAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRR 544
Query: 275 LEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTE 334
LEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTE
Sbjct: 545 LEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTE 604
Query: 335 DQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVD 394
DQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVD
Sbjct: 605 DQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVD 664
Query: 395 GEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR 454
GEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
Sbjct: 665 GEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR 724
>gi|32455250 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
isoform 3 [Homo sapiens]
Length = 424
Score = 853 bits (2205), Expect = 0.0
Identities = 418/418 (100%), Positives = 418/418 (100%)
Query: 37 LPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHG 96
LPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHG
Sbjct: 7 LPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHG 66
Query: 97 DYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLY 156
DYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLY
Sbjct: 67 DYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLY 126
Query: 157 PVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEA 216
PVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEA
Sbjct: 127 PVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEA 186
Query: 217 FNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLE 276
FNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLE
Sbjct: 187 FNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLE 246
Query: 277 EDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQ 336
EDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQ
Sbjct: 247 EDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQ 306
Query: 337 YSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGE 396
YSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGE
Sbjct: 307 YSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGE 366
Query: 397 VKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR 454
VKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
Sbjct: 367 VKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR 424
>gi|166795247 phosphoinositide-3-kinase, regulatory subunit 3 (p55,
gamma) [Homo sapiens]
Length = 461
Score = 723 bits (1867), Expect = 0.0
Identities = 355/455 (78%), Positives = 404/455 (88%), Gaps = 4/455 (0%)
Query: 1 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVA-NNGM-NNNMSL 58
MYNTVW+M+ D ++ + + T+L+FYIEMDPPALPPKPPKP T A NGM ++++SL
Sbjct: 1 MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPMTSAVPNGMKDSSVSL 60
Query: 59 QDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDG 118
QDAEWYWGDISREEVN+KLRD DGTFLVRDASTKM GDYTLTLRKGGNNKLIKI+HRDG
Sbjct: 61 QDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDG 120
Query: 119 KYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKK 178
KYGFSDPLTF+SVVELINHY +ESLAQYNPKLDVKL+YPVS+YQQDQ+VKEDNI+AVGKK
Sbjct: 121 KYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKK 180
Query: 179 LHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEY 238
L EY++Q+QEKS+EYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQC TQE++SKEY
Sbjct: 181 LQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEY 240
Query: 239 IEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKP 298
IE+F+REGNEKEI+RIM NYDKLKSR+ EI DS+ RLE+DLK QA + REIDK+MNSIKP
Sbjct: 241 IERFRREGNEKEIERIMMNYDKLKSRLGEIHDSKMRLEQDLKNQALDNREIDKKMNSIKP 300
Query: 299 DLIQLRKTRDQYLMWLTQKGVRQKKLNEWLG--NENTEDQYSLVEDDEDLPHHDEKTWNV 356
DLIQLRK RDQ+L+WL KGVRQK+LN WLG NE+ ++ Y + E+DE+LPH+DEKTW V
Sbjct: 301 DLIQLRKIRDQHLVWLNHKGVRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKTWFV 360
Query: 357 GSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYN 416
NR +AE+LL GK DG FL+RESSK+GCYACSVV DGEVKHCVI TA GYGFAEPYN
Sbjct: 361 EDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYN 420
Query: 417 LYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQ 451
LYSSLKELVLHYQ TSLVQHNDSLNV LAYPV+AQ
Sbjct: 421 LYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQ 455
Score = 66.6 bits (161), Expect = 4e-11
Identities = 40/102 (39%), Positives = 56/102 (54%), Gaps = 3/102 (2%)
Query: 354 WNVGSSNRNKAENLLRGKRDGTFLVRESSK--QGCYACSVVVDGEVKHCVINKTATGYGF 411
W G +R + + LR DGTFLVR++S QG Y ++ G K I YGF
Sbjct: 65 WYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDGKYGF 124
Query: 412 AEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQR 453
++P ++S+ EL+ HY H SL Q+N L+V L YPV Q+
Sbjct: 125 SDPLT-FNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQ 165
>gi|166795245 phosphoinositide-3-kinase, regulatory subunit 3 (p55,
gamma) [Homo sapiens]
Length = 461
Score = 723 bits (1867), Expect = 0.0
Identities = 355/455 (78%), Positives = 404/455 (88%), Gaps = 4/455 (0%)
Query: 1 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVA-NNGM-NNNMSL 58
MYNTVW+M+ D ++ + + T+L+FYIEMDPPALPPKPPKP T A NGM ++++SL
Sbjct: 1 MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPMTSAVPNGMKDSSVSL 60
Query: 59 QDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDG 118
QDAEWYWGDISREEVN+KLRD DGTFLVRDASTKM GDYTLTLRKGGNNKLIKI+HRDG
Sbjct: 61 QDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDG 120
Query: 119 KYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKK 178
KYGFSDPLTF+SVVELINHY +ESLAQYNPKLDVKL+YPVS+YQQDQ+VKEDNI+AVGKK
Sbjct: 121 KYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKK 180
Query: 179 LHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEY 238
L EY++Q+QEKS+EYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQC TQE++SKEY
Sbjct: 181 LQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEY 240
Query: 239 IEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKP 298
IE+F+REGNEKEI+RIM NYDKLKSR+ EI DS+ RLE+DLK QA + REIDK+MNSIKP
Sbjct: 241 IERFRREGNEKEIERIMMNYDKLKSRLGEIHDSKMRLEQDLKNQALDNREIDKKMNSIKP 300
Query: 299 DLIQLRKTRDQYLMWLTQKGVRQKKLNEWLG--NENTEDQYSLVEDDEDLPHHDEKTWNV 356
DLIQLRK RDQ+L+WL KGVRQK+LN WLG NE+ ++ Y + E+DE+LPH+DEKTW V
Sbjct: 301 DLIQLRKIRDQHLVWLNHKGVRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKTWFV 360
Query: 357 GSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYN 416
NR +AE+LL GK DG FL+RESSK+GCYACSVV DGEVKHCVI TA GYGFAEPYN
Sbjct: 361 EDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYN 420
Query: 417 LYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQ 451
LYSSLKELVLHYQ TSLVQHNDSLNV LAYPV+AQ
Sbjct: 421 LYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQ 455
Score = 66.6 bits (161), Expect = 4e-11
Identities = 40/102 (39%), Positives = 56/102 (54%), Gaps = 3/102 (2%)
Query: 354 WNVGSSNRNKAENLLRGKRDGTFLVRESSK--QGCYACSVVVDGEVKHCVINKTATGYGF 411
W G +R + + LR DGTFLVR++S QG Y ++ G K I YGF
Sbjct: 65 WYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDGKYGF 124
Query: 412 AEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQR 453
++P ++S+ EL+ HY H SL Q+N L+V L YPV Q+
Sbjct: 125 SDPLT-FNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQ 165
>gi|4826908 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
[Homo sapiens]
Length = 728
Score = 667 bits (1722), Expect = 0.0
Identities = 323/425 (76%), Positives = 379/425 (89%), Gaps = 7/425 (1%)
Query: 31 EMDPPALPPKPPK----PTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFL 86
E+ PPALPPKPPK PT +AN G + SLQDAEWYWGDISREEVNEKLRDT DGTFL
Sbjct: 296 EVAPPALPPKPPKAKPAPTVLANGG--SPPSLQDAEWYWGDISREEVNEKLRDTPDGTFL 353
Query: 87 VRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQY 146
VRDAS+K+ G+YTLTLRKGGNNKLIK+FHRDG YGFS+PLTF SVV+LINHYR+ESLAQY
Sbjct: 354 VRDASSKIQGEYTLTLRKGGNNKLIKVFHRDGHYGFSEPLTFCSVVDLINHYRHESLAQY 413
Query: 147 NPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQE 206
N KLD +LLYPVSKYQQDQ+VKED++EAVG +L Y+ Q+Q+KSREYD+LYEEYTRTSQE
Sbjct: 414 NAKLDTRLLYPVSKYQQDQIVKEDSVEAVGAQLKVYHQQYQDKSREYDQLYEEYTRTSQE 473
Query: 207 IQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRIS 266
+QMKRTAIEAFNETIKIFEEQ QTQE+ SKEY+E+F+REGNEKE+QRI+ N ++LKSRI+
Sbjct: 474 LQMKRTAIEAFNETIKIFEEQGQTQEKCSKEYLERFRREGNEKEMQRILLNSERLKSRIA 533
Query: 267 EIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNE 326
EI +SR +LE+ L+ QA++ REIDKRMNS+KPDL+QLRK RDQYL+WLTQKG RQKK+NE
Sbjct: 534 EIHESRTKLEQQLRAQASDNREIDKRMNSLKPDLMQLRKIRDQYLVWLTQKGARQKKINE 593
Query: 327 WLGNEN-TEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQG 385
WLG +N TEDQY+L+ED++DLPHH+E+TW VG NR +AE +L GKRDGTFL+RESS++G
Sbjct: 594 WLGIKNETEDQYALMEDEDDLPHHEERTWYVGKINRTQAEEMLSGKRDGTFLIRESSQRG 653
Query: 386 CYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLA 445
CYACSVVVDG+ KHCVI +TATG+GFAEPYNLY SLKELVLHYQH SLVQHND+L VTLA
Sbjct: 654 CYACSVVVDGDTKHCVIYRTATGFGFAEPYNLYGSLKELVLHYQHASLVQHNDALTVTLA 713
Query: 446 YPVYA 450
+PV A
Sbjct: 714 HPVRA 718
Score = 64.3 bits (155), Expect = 2e-10
Identities = 39/109 (35%), Positives = 56/109 (51%), Gaps = 3/109 (2%)
Query: 347 PHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSK--QGCYACSVVVDGEVKHCVINK 404
P + W G +R + LR DGTFLVR++S QG Y ++ G K +
Sbjct: 323 PSLQDAEWYWGDISREEVNEKLRDTPDGTFLVRDASSKIQGEYTLTLRKGGNNKLIKVFH 382
Query: 405 TATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQR 453
YGF+EP + S+ +L+ HY+H SL Q+N L+ L YPV Q+
Sbjct: 383 RDGHYGFSEPLT-FCSVVDLINHYRHESLAQYNAKLDTRLLYPVSKYQQ 430
>gi|120432042 vav 3 guanine nucleotide exchange factor isoform 2
[Homo sapiens]
Length = 287
Score = 58.9 bits (141), Expect = 9e-09
Identities = 31/95 (32%), Positives = 53/95 (55%), Gaps = 1/95 (1%)
Query: 63 WYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGF 122
WY G + R + +L + + T+LVR TK G+Y ++++ K IKI RDG +
Sbjct: 112 WYAGAMERLQAETELINRVNSTYLVRHR-TKESGEYAISIKYNNEAKHIKILTRDGFFHI 170
Query: 123 SDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYP 157
++ F S++EL+ +Y++ SL + LD L +P
Sbjct: 171 AENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFP 205
Score = 52.8 bits (125), Expect = 7e-07
Identities = 34/95 (35%), Positives = 51/95 (53%), Gaps = 2/95 (2%)
Query: 354 WNVGSSNRNKAENLLRGKRDGTFLVRESSKQ-GCYACSVVVDGEVKHCVINKTATGYGFA 412
W G+ R +AE L + + T+LVR +K+ G YA S+ + E KH I T G+
Sbjct: 112 WYAGAMERLQAETELINRVNSTYLVRHRTKESGEYAISIKYNNEAKHIKI-LTRDGFFHI 170
Query: 413 EPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYP 447
+ SL ELV +Y+H SL + +L+ TL +P
Sbjct: 171 AENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFP 205
>gi|120432044 vav 3 guanine nucleotide exchange factor isoform 1
[Homo sapiens]
Length = 847
Score = 58.9 bits (141), Expect = 9e-09
Identities = 31/95 (32%), Positives = 53/95 (55%), Gaps = 1/95 (1%)
Query: 63 WYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGF 122
WY G + R + +L + + T+LVR TK G+Y ++++ K IKI RDG +
Sbjct: 672 WYAGAMERLQAETELINRVNSTYLVRHR-TKESGEYAISIKYNNEAKHIKILTRDGFFHI 730
Query: 123 SDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYP 157
++ F S++EL+ +Y++ SL + LD L +P
Sbjct: 731 AENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFP 765
Score = 52.8 bits (125), Expect = 7e-07
Identities = 34/95 (35%), Positives = 51/95 (53%), Gaps = 2/95 (2%)
Query: 354 WNVGSSNRNKAENLLRGKRDGTFLVRESSKQ-GCYACSVVVDGEVKHCVINKTATGYGFA 412
W G+ R +AE L + + T+LVR +K+ G YA S+ + E KH I T G+
Sbjct: 672 WYAGAMERLQAETELINRVNSTYLVRHRTKESGEYAISIKYNNEAKHIKI-LTRDGFFHI 730
Query: 413 EPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYP 447
+ SL ELV +Y+H SL + +L+ TL +P
Sbjct: 731 AENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFP 765
>gi|4507263 suppressor of cytokine signaling-2 [Homo sapiens]
Length = 198
Score = 58.2 bits (139), Expect = 2e-08
Identities = 31/85 (36%), Positives = 48/85 (56%), Gaps = 12/85 (14%)
Query: 63 WYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTL--RKGGNNKLIKIFHRDGKY 120
WYWG ++ E EKL++ +GTFL+RD+S H DY LT+ + ++I ++DGK+
Sbjct: 48 WYWGSMTVNEAKEKLKEAPEGTFLIRDSS---HSDYLLTISVKTSAGPTNLRIEYQDGKF 104
Query: 121 GFSDPL-------TFSSVVELINHY 138
+ F SVV LI++Y
Sbjct: 105 RLDSIICVKSKLKQFDSVVHLIDYY 129
Score = 29.3 bits (64), Expect = 7.7
Identities = 13/29 (44%), Positives = 19/29 (65%)
Query: 354 WNVGSSNRNKAENLLRGKRDGTFLVRESS 382
W GS N+A+ L+ +GTFL+R+SS
Sbjct: 48 WYWGSMTVNEAKEKLKEAPEGTFLIRDSS 76
>gi|7108367 vav 1 guanine nucleotide exchange factor [Homo sapiens]
Length = 845
Score = 56.2 bits (134), Expect = 6e-08
Identities = 41/112 (36%), Positives = 54/112 (48%), Gaps = 5/112 (4%)
Query: 344 EDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGC-YACSVVVDGEVKHCVI 402
+DL H W G R AE++L + DGTFLVR+ K +A S+ + EVKH I
Sbjct: 664 QDLSVH---LWYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKI 720
Query: 403 NKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR 454
TA G + L ELV YQ SL SL+ TL +P ++R
Sbjct: 721 -MTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKEPEKR 771
Score = 51.2 bits (121), Expect = 2e-06
Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 1/95 (1%)
Query: 63 WYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGF 122
WY G + R L + +DGTFLVR K ++ ++++ K IKI +G Y
Sbjct: 671 WYAGPMERAGAESILANRSDGTFLVRQR-VKDAAEFAISIKYNVEVKHIKIMTAEGLYRI 729
Query: 123 SDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYP 157
++ F + EL+ Y+ SL LD L +P
Sbjct: 730 TEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFP 764
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 55.8 bits (133), Expect = 8e-08
Identities = 50/216 (23%), Positives = 100/216 (46%), Gaps = 24/216 (11%)
Query: 168 KEDNIEAVGKKLHEYNT--QFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFE 225
KE+ I + +K+HE + +EK +E +++ E+ R QE +M R E I+ E
Sbjct: 389 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ-----EEKIREQE 443
Query: 226 EQCQTQER---YSKEYI---EKFKREGNEKEIQRIMHNYDKL---------KSRISEIID 270
E+ + QE+ +E I EK + E +E + + +K+ K ++ E +
Sbjct: 444 EKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEE 503
Query: 271 SRRRLEEDLKKQAAEYREIDKRMNSIKPDL-IQLRKTRDQYLMWLTQKGVRQKKLNEWLG 329
R+ EE + +Q + RE ++++ + + Q K R+Q MW ++ + +++ W
Sbjct: 504 KIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQE-KIWEE 562
Query: 330 NENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAE 365
+ E + + +E + +EK W R + E
Sbjct: 563 EKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEE 598
Score = 48.1 bits (113), Expect = 2e-05
Identities = 41/170 (24%), Positives = 82/170 (48%), Gaps = 15/170 (8%)
Query: 187 QEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREG 246
+EK E ++++EE R QE +M R E I+ EE+ QE +E E KR+
Sbjct: 550 EEKMHEQEKIWEEEKRQEQEDKMWRQ-----EEKIREQEEKVWRQEEKIREQEE--KRQE 602
Query: 247 NEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLI-QLRK 305
E+++ + + + +I E + R EE +++Q +E +++M + + Q K
Sbjct: 603 QEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEK 662
Query: 306 TRDQ-YLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTW 354
++Q MW ++ +R+++ + E + + E +E + +EK W
Sbjct: 663 MQEQEETMWRQEEKIREQE------KKIREQEEKIREQEEMMQEQEEKMW 706
Score = 45.1 bits (105), Expect = 1e-04
Identities = 50/221 (22%), Positives = 98/221 (44%), Gaps = 24/221 (10%)
Query: 138 YRN----ESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQF--QEKSR 191
YRN E L + N KL KL S+ + Q+ N++ + +KL Q+
Sbjct: 210 YRNTITDEELKEKNAKLQEKLQLVESEKSEIQL----NVKELKRKLERAKLLLPQQQLQA 265
Query: 192 EYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEI 251
E D L +E S ++Q + E +N + EE+ QE +E+ EK + + E++I
Sbjct: 266 EADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ--EEKI 323
Query: 252 QRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYL 311
+ + + +I E + RR EE + ++ + R ++ M + + R + +
Sbjct: 324 R-------EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM-----RRQEEM 371
Query: 312 MWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEK 352
MW ++ +R+++ W E + + + E + +EK
Sbjct: 372 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 412
Score = 35.0 bits (79), Expect = 0.14
Identities = 26/140 (18%), Positives = 70/140 (50%), Gaps = 7/140 (5%)
Query: 161 YQQDQVVKE--DNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFN 218
++Q++ ++E + I+ +K+ E + +E+ E+ +++ + ++
Sbjct: 608 WKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 667
Query: 219 ETIKIFEEQCQTQERYSKEYIEKFK--REGNEKEIQRIMHNYDKL---KSRISEIIDSRR 273
ET+ EE+ + QE+ +E EK + E +++ +++ +K+ + ++ E + R
Sbjct: 668 ETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 727
Query: 274 RLEEDLKKQAAEYREIDKRM 293
R EE + +Q R+ +++M
Sbjct: 728 RQEEKMWEQEVRLRQQEEKM 747
>gi|21450785 suppressor of cytokine signaling 6 [Homo sapiens]
Length = 535
Score = 55.8 bits (133), Expect = 8e-08
Identities = 46/166 (27%), Positives = 75/166 (45%), Gaps = 21/166 (12%)
Query: 18 TDINCGTDLMFYIEMDPPALPPKPPKPTTVANNGMNNNMSLQDA-------EWYWGDISR 70
T+ + + ++ DP + P +V ++G SL + WYWG I+R
Sbjct: 332 TEAHVAESMRCHLNFDPNSAPGVARVYDSVQSSGPMVVTSLTEELKKLAKQGWYWGPITR 391
Query: 71 EEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGF---SDPLT 127
E KL + DG+FLVRD+S + +L+ R G +I H +G++ F D
Sbjct: 392 WEAEGKLANVPDGSFLVRDSSDDRY-LLSLSFRSHGKTLHTRIEHSNGRFSFYEQPDVEG 450
Query: 128 FSSVVELINH----YRNESLAQYNPKL------DVKLLYPVSKYQQ 163
+S+V+LI H N + +L V+L PVS++ Q
Sbjct: 451 HTSIVDLIEHSIRDSENGAFCYSRSRLPGSATYPVRLTNPVSRFMQ 496
Score = 30.8 bits (68), Expect = 2.6
Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
Query: 344 EDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESS-KQGCYACSVVVDGEVKHCVI 402
E+L ++ W G R +AE L DG+FLVR+SS + + S G+ H I
Sbjct: 374 EELKKLAKQGWYWGPITRWEAEGKLANVPDGSFLVRDSSDDRYLLSLSFRSHGKTLHTRI 433
Query: 403 NKTATGYGFAEPYNL--YSSLKELVLH 427
+ + F E ++ ++S+ +L+ H
Sbjct: 434 EHSNGRFSFYEQPDVEGHTSIVDLIEH 460
>gi|117320537 phospholipase C, gamma 2 [Homo sapiens]
Length = 1265
Score = 55.5 bits (132), Expect = 1e-07
Identities = 36/101 (35%), Positives = 52/101 (51%), Gaps = 7/101 (6%)
Query: 349 HDEKTWNVGSSNRNKAENLL-RGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTAT 407
H+ K W S +R +AE++L R RDG FL+R+ YA + G+VKHC IN+
Sbjct: 641 HESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGSDSYAITFRARGKVKHCRINRDGR 700
Query: 408 GYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPV 448
+ + SL ELV +Y+ SL + + L YPV
Sbjct: 701 HFVLGTS-AYFESLVELVSYYEKHSLYR-----KMRLRYPV 735
Score = 48.1 bits (113), Expect = 2e-05
Identities = 41/108 (37%), Positives = 53/108 (49%), Gaps = 16/108 (14%)
Query: 341 EDDEDLP----HHDEKTWNVGSSNRNKAENLLR------GKRDGTFLVRESSK-QGCYAC 389
E +D+P H EK ++ R AE LL+ G +DGTFLVRES Y
Sbjct: 516 EVPQDIPPTELHFGEKWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTL 575
Query: 390 SVVVDGEVKHCVINKTATGYGFAEPY---NL-YSSLKELVLHYQHTSL 433
S G V+HC I T G G + Y NL +SS+ L+ HY+ T L
Sbjct: 576 SFWRSGRVQHCRIRSTMEG-GTLKYYLTDNLTFSSIYALIQHYRETHL 622
Score = 45.1 bits (105), Expect = 1e-04
Identities = 33/93 (35%), Positives = 46/93 (49%), Gaps = 12/93 (12%)
Query: 62 EWYWGDISREEVNEKLRDT-------ADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIF 114
+W+ + + EKL DGTFLVR++ T DYTL+ + G + +I
Sbjct: 531 KWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRESET-FPNDYTLSFWRSGRVQHCRIR 589
Query: 115 HR-DG---KYGFSDPLTFSSVVELINHYRNESL 143
+G KY +D LTFSS+ LI HYR L
Sbjct: 590 STMEGGTLKYYLTDNLTFSSIYALIQHYRETHL 622
>gi|4557377 Bruton agammaglobulinemia tyrosine kinase [Homo sapiens]
Length = 659
Score = 55.1 bits (131), Expect = 1e-07
Identities = 50/183 (27%), Positives = 85/183 (46%), Gaps = 22/183 (12%)
Query: 278 DLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQY 337
+LKK A Y + N + QLRK D+Y + L + + + + G E
Sbjct: 215 ELKKVVALYDYMPMNANDL-----QLRKG-DEYFI-LEESNLPWWRARDKNGQEGYIPSN 267
Query: 338 SLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGK-RDGTFLVRESSKQGCYACSVVV--- 393
+ E ++ + ++ W R++AE LL+ + ++G F+VR+SSK G Y SV
Sbjct: 268 YVTEAEDSIEMYE---WYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKAGKYTVSVFAKST 324
Query: 394 ---DGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYA 450
G ++H V+ T + +L+S++ EL+ ++QH S L L YPV
Sbjct: 325 GDPQGVIRHYVVCSTPQSQYYLAEKHLFSTIPELINYHQHNSA-----GLISRLKYPVSQ 379
Query: 451 QQR 453
Q +
Sbjct: 380 QNK 382
Score = 38.5 bits (88), Expect = 0.013
Identities = 30/116 (25%), Positives = 58/116 (50%), Gaps = 15/116 (12%)
Query: 57 SLQDAEWYWGDISREEVNEKLRDTA-DGTFLVRDASTKMHGDYTLTL-------RKGGNN 108
S++ EWY ++R + + L+ +G F+VRD+S G YT+++ +G
Sbjct: 275 SIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKA--GKYTVSVFAKSTGDPQGVIR 332
Query: 109 KLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQD 164
+ +Y ++ FS++ ELIN++++ S L +L YPVS+ ++
Sbjct: 333 HYVVCSTPQSQYYLAEKHLFSTIPELINYHQHNSAG-----LISRLKYPVSQQNKN 383
>gi|153266778 arg tyrosine kinase isoform c [Homo sapiens]
Length = 1167
Score = 53.9 bits (128), Expect = 3e-07
Identities = 37/99 (37%), Positives = 53/99 (53%), Gaps = 6/99 (6%)
Query: 350 DEKTWNVGSSNRNKAENLLRGKRDGTFLVRES-SKQGCYACSVVVDGEVKHCVINKTATG 408
++ +W G +R+ AE LL +G+FLVRES S G + S+ +G V H IN TA G
Sbjct: 154 EKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADG 213
Query: 409 YGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYP 447
+ + +S+L ELV H+ + D L TL YP
Sbjct: 214 KVYVTAESRFSTLAELVHHHSTVA-----DGLVTTLHYP 247
Score = 42.4 bits (98), Expect = 9e-04
Identities = 29/98 (29%), Positives = 48/98 (48%), Gaps = 12/98 (12%)
Query: 47 VANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGG 106
V +N + SL+ WY G +SR L +G+FLVR+ S G +++LR G
Sbjct: 142 VPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRE-SESSPGQLSISLRYEG 200
Query: 107 NNKLIKIFH------RDGKYGFSDPLTFSSVVELINHY 138
+++H DGK + FS++ EL++H+
Sbjct: 201 -----RVYHYRINTTADGKVYVTAESRFSTLAELVHHH 233
>gi|6382062 arg tyrosine kinase isoform b [Homo sapiens]
Length = 1182
Score = 53.9 bits (128), Expect = 3e-07
Identities = 37/99 (37%), Positives = 53/99 (53%), Gaps = 6/99 (6%)
Query: 350 DEKTWNVGSSNRNKAENLLRGKRDGTFLVRES-SKQGCYACSVVVDGEVKHCVINKTATG 408
++ +W G +R+ AE LL +G+FLVRES S G + S+ +G V H IN TA G
Sbjct: 169 EKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADG 228
Query: 409 YGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYP 447
+ + +S+L ELV H+ + D L TL YP
Sbjct: 229 KVYVTAESRFSTLAELVHHHSTVA-----DGLVTTLHYP 262
Score = 42.4 bits (98), Expect = 9e-04
Identities = 29/98 (29%), Positives = 48/98 (48%), Gaps = 12/98 (12%)
Query: 47 VANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGG 106
V +N + SL+ WY G +SR L +G+FLVR+ S G +++LR G
Sbjct: 157 VPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRE-SESSPGQLSISLRYEG 215
Query: 107 NNKLIKIFH------RDGKYGFSDPLTFSSVVELINHY 138
+++H DGK + FS++ EL++H+
Sbjct: 216 -----RVYHYRINTTADGKVYVTAESRFSTLAELVHHH 248
>gi|209862778 arg tyrosine kinase isoform e [Homo sapiens]
Length = 542
Score = 53.9 bits (128), Expect = 3e-07
Identities = 37/99 (37%), Positives = 53/99 (53%), Gaps = 6/99 (6%)
Query: 350 DEKTWNVGSSNRNKAENLLRGKRDGTFLVRES-SKQGCYACSVVVDGEVKHCVINKTATG 408
++ +W G +R+ AE LL +G+FLVRES S G + S+ +G V H IN TA G
Sbjct: 148 EKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADG 207
Query: 409 YGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYP 447
+ + +S+L ELV H+ + D L TL YP
Sbjct: 208 KVYVTAESRFSTLAELVHHHSTVA-----DGLVTTLHYP 241
Score = 42.4 bits (98), Expect = 9e-04
Identities = 29/98 (29%), Positives = 48/98 (48%), Gaps = 12/98 (12%)
Query: 47 VANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGG 106
V +N + SL+ WY G +SR L +G+FLVR+ S G +++LR G
Sbjct: 136 VPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRE-SESSPGQLSISLRYEG 194
Query: 107 NNKLIKIFH------RDGKYGFSDPLTFSSVVELINHY 138
+++H DGK + FS++ EL++H+
Sbjct: 195 -----RVYHYRINTTADGKVYVTAESRFSTLAELVHHH 227
>gi|209862772 arg tyrosine kinase isoform d [Homo sapiens]
Length = 1064
Score = 53.9 bits (128), Expect = 3e-07
Identities = 37/99 (37%), Positives = 53/99 (53%), Gaps = 6/99 (6%)
Query: 350 DEKTWNVGSSNRNKAENLLRGKRDGTFLVRES-SKQGCYACSVVVDGEVKHCVINKTATG 408
++ +W G +R+ AE LL +G+FLVRES S G + S+ +G V H IN TA G
Sbjct: 154 EKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADG 213
Query: 409 YGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYP 447
+ + +S+L ELV H+ + D L TL YP
Sbjct: 214 KVYVTAESRFSTLAELVHHHSTVA-----DGLVTTLHYP 247
Score = 42.4 bits (98), Expect = 9e-04
Identities = 29/98 (29%), Positives = 48/98 (48%), Gaps = 12/98 (12%)
Query: 47 VANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGG 106
V +N + SL+ WY G +SR L +G+FLVR+ S G +++LR G
Sbjct: 142 VPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRE-SESSPGQLSISLRYEG 200
Query: 107 NNKLIKIFH------RDGKYGFSDPLTFSSVVELINHY 138
+++H DGK + FS++ EL++H+
Sbjct: 201 -----RVYHYRINTTADGKVYVTAESRFSTLAELVHHH 233
>gi|153266757 arg tyrosine kinase isoform a [Homo sapiens]
Length = 1146
Score = 53.9 bits (128), Expect = 3e-07
Identities = 37/99 (37%), Positives = 53/99 (53%), Gaps = 6/99 (6%)
Query: 350 DEKTWNVGSSNRNKAENLLRGKRDGTFLVRES-SKQGCYACSVVVDGEVKHCVINKTATG 408
++ +W G +R+ AE LL +G+FLVRES S G + S+ +G V H IN TA G
Sbjct: 133 EKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADG 192
Query: 409 YGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYP 447
+ + +S+L ELV H+ + D L TL YP
Sbjct: 193 KVYVTAESRFSTLAELVHHHSTVA-----DGLVTTLHYP 226
Score = 42.4 bits (98), Expect = 9e-04
Identities = 29/98 (29%), Positives = 48/98 (48%), Gaps = 12/98 (12%)
Query: 47 VANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGG 106
V +N + SL+ WY G +SR L +G+FLVR+ S G +++LR G
Sbjct: 121 VPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRE-SESSPGQLSISLRYEG 179
Query: 107 NNKLIKIFH------RDGKYGFSDPLTFSSVVELINHY 138
+++H DGK + FS++ EL++H+
Sbjct: 180 -----RVYHYRINTTADGKVYVTAESRFSTLAELVHHH 212
>gi|21450844 megakaryocyte-associated tyrosine kinase isoform c
[Homo sapiens]
Length = 466
Score = 53.5 bits (127), Expect = 4e-07
Identities = 30/99 (30%), Positives = 53/99 (53%), Gaps = 6/99 (6%)
Query: 63 WYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGF 122
W+ G IS +E ++L+ DG FLVR+ S + GDY L + G + ++ HRDG
Sbjct: 81 WFHGKISGQEAVQQLQPPEDGLFLVRE-SARHPGDYVLCVSFGRDVIHYRVLHRDGHLTI 139
Query: 123 SDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKY 161
+ + F ++++++ HY + A + KL+ P K+
Sbjct: 140 DEAVFFCNLMDMVEHYSKDKGA-----ICTKLVRPKRKH 173
>gi|21450842 megakaryocyte-associated tyrosine kinase isoform b
[Homo sapiens]
Length = 508
Score = 53.5 bits (127), Expect = 4e-07
Identities = 30/99 (30%), Positives = 53/99 (53%), Gaps = 6/99 (6%)
Query: 63 WYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGF 122
W+ G IS +E ++L+ DG FLVR+ S + GDY L + G + ++ HRDG
Sbjct: 123 WFHGKISGQEAVQQLQPPEDGLFLVRE-SARHPGDYVLCVSFGRDVIHYRVLHRDGHLTI 181
Query: 123 SDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKY 161
+ + F ++++++ HY + A + KL+ P K+
Sbjct: 182 DEAVFFCNLMDMVEHYSKDKGA-----ICTKLVRPKRKH 215
>gi|21450846 megakaryocyte-associated tyrosine kinase isoform a
[Homo sapiens]
Length = 507
Score = 53.5 bits (127), Expect = 4e-07
Identities = 30/99 (30%), Positives = 53/99 (53%), Gaps = 6/99 (6%)
Query: 63 WYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGF 122
W+ G IS +E ++L+ DG FLVR+ S + GDY L + G + ++ HRDG
Sbjct: 122 WFHGKISGQEAVQQLQPPEDGLFLVRE-SARHPGDYVLCVSFGRDVIHYRVLHRDGHLTI 180
Query: 123 SDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKY 161
+ + F ++++++ HY + A + KL+ P K+
Sbjct: 181 DEAVFFCNLMDMVEHYSKDKGA-----ICTKLVRPKRKH 214
>gi|197304715 vav 2 guanine nucleotide exchange factor isoform 1
[Homo sapiens]
Length = 878
Score = 53.5 bits (127), Expect = 4e-07
Identities = 33/101 (32%), Positives = 52/101 (51%), Gaps = 2/101 (1%)
Query: 354 WNVGSSNRNKAENLLRGKRDGTFLVRESSKQG-CYACSVVVDGEVKHCVINKTATGYGFA 412
W G+ R + +NLL+ GT+L+RE + +A S+ + EVKH + +
Sbjct: 673 WFAGNMERQQTDNLLKSHASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDNWIHIT 732
Query: 413 EPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQR 453
E + SL ELV +YQ SL + L+ TL YP +++R
Sbjct: 733 EA-KKFDSLLELVEYYQCHSLKESFKQLDTTLKYPYKSRER 772
Score = 52.4 bits (124), Expect = 8e-07
Identities = 25/95 (26%), Positives = 52/95 (54%), Gaps = 1/95 (1%)
Query: 63 WYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGF 122
W+ G++ R++ + L+ A GT+L+R+ + + ++++ K IK+ +D
Sbjct: 673 WFAGNMERQQTDNLLKSHASGTYLIRERPAEAER-FAISIKFNDEVKHIKVVEKDNWIHI 731
Query: 123 SDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYP 157
++ F S++EL+ +Y+ SL + +LD L YP
Sbjct: 732 TEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYP 766
>gi|40549448 vav 2 guanine nucleotide exchange factor isoform 2
[Homo sapiens]
Length = 839
Score = 53.5 bits (127), Expect = 4e-07
Identities = 33/101 (32%), Positives = 52/101 (51%), Gaps = 2/101 (1%)
Query: 354 WNVGSSNRNKAENLLRGKRDGTFLVRESSKQG-CYACSVVVDGEVKHCVINKTATGYGFA 412
W G+ R + +NLL+ GT+L+RE + +A S+ + EVKH + +
Sbjct: 663 WFAGNMERQQTDNLLKSHASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDNWIHIT 722
Query: 413 EPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQR 453
E + SL ELV +YQ SL + L+ TL YP +++R
Sbjct: 723 EA-KKFDSLLELVEYYQCHSLKESFKQLDTTLKYPYKSRER 762
Score = 52.4 bits (124), Expect = 8e-07
Identities = 25/95 (26%), Positives = 52/95 (54%), Gaps = 1/95 (1%)
Query: 63 WYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGF 122
W+ G++ R++ + L+ A GT+L+R+ + + ++++ K IK+ +D
Sbjct: 663 WFAGNMERQQTDNLLKSHASGTYLIRERPAEAER-FAISIKFNDEVKHIKVVEKDNWIHI 721
Query: 123 SDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYP 157
++ F S++EL+ +Y+ SL + +LD L YP
Sbjct: 722 TEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYP 756
>gi|4502435 BMX non-receptor tyrosine kinase [Homo sapiens]
Length = 675
Score = 52.4 bits (124), Expect = 8e-07
Identities = 40/171 (23%), Positives = 79/171 (46%), Gaps = 25/171 (14%)
Query: 284 AEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTED-------- 335
A+Y K++ +P+ R+ + W + ++ +E + + N ++
Sbjct: 214 AQYDSNSKKIYGSQPNFNMQYIPREDFPDWWQVRKLKSSSSSEDVASSNQKERNVNHTTS 273
Query: 336 -------QYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGK-RDGTFLVRESSKQGCY 387
+ S E++E+L +D W G+ +R+++E LLR K ++G F+VR SS+ G Y
Sbjct: 274 KISWEFPESSSSEEEENLDDYD---WFAGNISRSQSEQLLRQKGKEGAFMVRNSSQVGMY 330
Query: 388 ACSVV------VDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTS 432
S+ G VKH ++ A + + S+ +L+ ++QH S
Sbjct: 331 TVSLFSKAVNDKKGTVKHYHVHTNAENKLYLAENYCFDSIPKLIHYHQHNS 381
Score = 42.0 bits (97), Expect = 0.001
Identities = 33/111 (29%), Positives = 61/111 (54%), Gaps = 15/111 (13%)
Query: 57 SLQDAEWYWGDISREEVNEKLRDTA-DGTFLVRDASTKMHGDYTLTL-RKGGNNK--LIK 112
+L D +W+ G+ISR + + LR +G F+VR++S G YT++L K N+K +K
Sbjct: 290 NLDDYDWFAGNISRSQSEQLLRQKGKEGAFMVRNSS--QVGMYTVSLFSKAVNDKKGTVK 347
Query: 113 IFH----RDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVS 159
+H + K ++ F S+ +LI+++++ S + +L +PVS
Sbjct: 348 HYHVHTNAENKLYLAENYCFDSIPKLIHYHQHNSAG-----MITRLRHPVS 393
>gi|42544182 BMX non-receptor tyrosine kinase [Homo sapiens]
Length = 675
Score = 52.4 bits (124), Expect = 8e-07
Identities = 40/171 (23%), Positives = 79/171 (46%), Gaps = 25/171 (14%)
Query: 284 AEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTED-------- 335
A+Y K++ +P+ R+ + W + ++ +E + + N ++
Sbjct: 214 AQYDSNSKKIYGSQPNFNMQYIPREDFPDWWQVRKLKSSSSSEDVASSNQKERNVNHTTS 273
Query: 336 -------QYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGK-RDGTFLVRESSKQGCY 387
+ S E++E+L +D W G+ +R+++E LLR K ++G F+VR SS+ G Y
Sbjct: 274 KISWEFPESSSSEEEENLDDYD---WFAGNISRSQSEQLLRQKGKEGAFMVRNSSQVGMY 330
Query: 388 ACSVV------VDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTS 432
S+ G VKH ++ A + + S+ +L+ ++QH S
Sbjct: 331 TVSLFSKAVNDKKGTVKHYHVHTNAENKLYLAENYCFDSIPKLIHYHQHNS 381
Score = 42.0 bits (97), Expect = 0.001
Identities = 33/111 (29%), Positives = 61/111 (54%), Gaps = 15/111 (13%)
Query: 57 SLQDAEWYWGDISREEVNEKLRDTA-DGTFLVRDASTKMHGDYTLTL-RKGGNNK--LIK 112
+L D +W+ G+ISR + + LR +G F+VR++S G YT++L K N+K +K
Sbjct: 290 NLDDYDWFAGNISRSQSEQLLRQKGKEGAFMVRNSS--QVGMYTVSLFSKAVNDKKGTVK 347
Query: 113 IFH----RDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVS 159
+H + K ++ F S+ +LI+++++ S + +L +PVS
Sbjct: 348 HYHVHTNAENKLYLAENYCFDSIPKLIHYHQHNSAG-----MITRLRHPVS 393
>gi|5174647 PTK6 protein tyrosine kinase 6 [Homo sapiens]
Length = 451
Score = 52.4 bits (124), Expect = 8e-07
Identities = 37/130 (28%), Positives = 69/130 (53%), Gaps = 9/130 (6%)
Query: 47 VANNGMNNNMSLQDAEWYWGDISREEVNEKLR--DTADGTFLVRDASTKMHGDYTLTLRK 104
V +N + +++ W++G ISR E +L+ A G FL+R S K DY L++R
Sbjct: 62 VPHNYLAERETVESEPWFFGCISRSEAVRRLQAEGNATGAFLIR-VSEKPSADYVLSVRD 120
Query: 105 GGNNKLIKIFHR-DGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQ 163
+ KI+ R G+ ++ ++F S+ EL+N++R +SL+ ++L P K++
Sbjct: 121 TQAVRHYKIWRRAGGRLHLNEAVSFLSLPELVNYHRAQSLSH-----GLRLAAPCRKHEP 175
Query: 164 DQVVKEDNIE 173
+ + D+ E
Sbjct: 176 EPLPHWDDWE 185
>gi|148596974 TXK tyrosine kinase [Homo sapiens]
Length = 527
Score = 52.4 bits (124), Expect = 8e-07
Identities = 44/159 (27%), Positives = 77/159 (48%), Gaps = 16/159 (10%)
Query: 297 KPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNV 356
+P + LR+ ++YL+ L + K + LGNE + E+ + + + W
Sbjct: 97 EPCNLALRRA-EEYLI-LEKYNPHWWKARDRLGNEGLIPSNYVTENK--ITNLEIYEWYH 152
Query: 357 GSSNRNKAENLLRGK-RDGTFLVRESSKQGCYACSVVV------DGEVKHCVINKTATGY 409
+ RN+AE+LLR + ++G F+VR+S G Y SV + + +KH I K +G
Sbjct: 153 RNITRNQAEHLLRQESKEGAFIVRDSRHLGSYTISVFMGARRSTEAAIKHYQIKKNDSGQ 212
Query: 410 GFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPV 448
+ + + S+ EL+ ++QH + L L YPV
Sbjct: 213 WYVAERHAFQSIPELIWYHQHNAA-----GLMTRLRYPV 246
>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform
1 [Homo sapiens]
Length = 1722
Score = 52.4 bits (124), Expect = 8e-07
Identities = 63/243 (25%), Positives = 112/243 (46%), Gaps = 42/243 (17%)
Query: 149 KLDVKLLYPVSKYQQD----QVVKEDNI--------EAVGKKLH----EYNTQFQEKS-R 191
K++ K L + K +QD ++ KE+ I E + LH E T+F+++ +
Sbjct: 215 KVEKKKLENIQKQEQDKMNDELYKEEKIWKEKFKQHEEYIRNLHLQMEEERTRFKDQQEK 274
Query: 192 EYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKF-----KREG 246
E + L ++ + +IQ K A A+ + I +EQ ++++R ++E+ EK K E
Sbjct: 275 EKNSLLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQIESKKRKAQEWKEKEAKIRQKEEE 334
Query: 247 NEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYRE-----IDKRMNSIKPDLI 301
N K ++ + RI E + +++ EE+ K++ EY E +R I + I
Sbjct: 335 NRKRLEE--------EQRIKE--ERKKQKEEERKRREKEYEEKKNIVKQEREQLISKEKI 384
Query: 302 QLRKTRDQYLM---WLTQKGVRQKKLN-EWLGNENTEDQYSLVEDDEDLPHHDEKTWNVG 357
LR+ Q L+ L + G K L+ E + N+ + +LV D+ D W V
Sbjct: 385 ILREDASQQLIISSALKKSGYNNKHLSLEDISNDKGDIAKNLV-DENSKKQEDVLLWLVE 443
Query: 358 SSN 360
SN
Sbjct: 444 ESN 446
>gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform
2 [Homo sapiens]
Length = 1336
Score = 52.4 bits (124), Expect = 8e-07
Identities = 63/243 (25%), Positives = 112/243 (46%), Gaps = 42/243 (17%)
Query: 149 KLDVKLLYPVSKYQQD----QVVKEDNI--------EAVGKKLH----EYNTQFQEKS-R 191
K++ K L + K +QD ++ KE+ I E + LH E T+F+++ +
Sbjct: 215 KVEKKKLENIQKQEQDKMNDELYKEEKIWKEKFKQHEEYIRNLHLQMEEERTRFKDQQEK 274
Query: 192 EYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKF-----KREG 246
E + L ++ + +IQ K A A+ + I +EQ ++++R ++E+ EK K E
Sbjct: 275 EKNSLLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQIESKKRKAQEWKEKEAKIRQKEEE 334
Query: 247 NEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYRE-----IDKRMNSIKPDLI 301
N K ++ + RI E + +++ EE+ K++ EY E +R I + I
Sbjct: 335 NRKRLEE--------EQRIKE--ERKKQKEEERKRREKEYEEKKNIVKQEREQLISKEKI 384
Query: 302 QLRKTRDQYLM---WLTQKGVRQKKLN-EWLGNENTEDQYSLVEDDEDLPHHDEKTWNVG 357
LR+ Q L+ L + G K L+ E + N+ + +LV D+ D W V
Sbjct: 385 ILREDASQQLIISSALKKSGYNNKHLSLEDISNDKGDIAKNLV-DENSKKQEDVLLWLVE 443
Query: 358 SSN 360
SN
Sbjct: 444 ESN 446
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,186,030
Number of Sequences: 37866
Number of extensions: 797272
Number of successful extensions: 5511
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 132
Number of HSP's successfully gapped in prelim test: 531
Number of HSP's that attempted gapping in prelim test: 4153
Number of HSP's gapped (non-prelim): 1559
length of query: 454
length of database: 18,247,518
effective HSP length: 106
effective length of query: 348
effective length of database: 14,233,722
effective search space: 4953335256
effective search space used: 4953335256
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.