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Search of human proteins with 31742498
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31742498 unc-84 homolog B [Homo sapiens]
(717 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31742498 unc-84 homolog B [Homo sapiens] 1425 0.0
gi|195972890 unc-84 homolog A isoform a [Homo sapiens] 358 1e-98
gi|110227866 unc-84 homolog A isoform b [Homo sapiens] 346 5e-95
gi|71834870 Sad1 and UNC84 domain containing 1 [Homo sapiens] 194 3e-49
gi|71834868 Sad1 and UNC84 domain containing 1 [Homo sapiens] 194 3e-49
gi|11037055 sperm associated antigen 4 [Homo sapiens] 160 4e-39
gi|21361792 sperm associated antigen 4-like [Homo sapiens] 140 3e-33
gi|148746195 trichohyalin [Homo sapiens] 54 7e-07
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 52 2e-06
gi|45439327 periplakin [Homo sapiens] 50 7e-06
gi|203096856 kinesin family member 7 [Homo sapiens] 50 9e-06
gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho... 49 2e-05
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho... 49 2e-05
gi|217416398 hyaluronan-mediated motility receptor isoform c [Ho... 49 2e-05
gi|217416394 hyaluronan-mediated motility receptor isoform b [Ho... 49 2e-05
gi|115527097 CDC42-binding protein kinase beta [Homo sapiens] 47 5e-05
gi|126723390 ankyrin repeat domain 24 [Homo sapiens] 46 1e-04
gi|7662176 ProSAPiP1 protein [Homo sapiens] 46 1e-04
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 45 2e-04
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 45 2e-04
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 45 2e-04
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 45 2e-04
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 45 2e-04
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 45 2e-04
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 45 2e-04
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 45 2e-04
gi|229577000 ecotropic viral integration site 5-like isoform 1 [... 45 3e-04
gi|21735548 centrosomal protein 2 [Homo sapiens] 45 3e-04
gi|56550043 sarcolemma associated protein [Homo sapiens] 45 3e-04
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 44 4e-04
>gi|31742498 unc-84 homolog B [Homo sapiens]
Length = 717
Score = 1425 bits (3688), Expect = 0.0
Identities = 717/717 (100%), Positives = 717/717 (100%)
Query: 1 MSRRSQRLTRYSQGDDDGSSSSGGSSVAGSQSTLFKDSPLRTLKRKSSNMKRLSPAPQLG 60
MSRRSQRLTRYSQGDDDGSSSSGGSSVAGSQSTLFKDSPLRTLKRKSSNMKRLSPAPQLG
Sbjct: 1 MSRRSQRLTRYSQGDDDGSSSSGGSSVAGSQSTLFKDSPLRTLKRKSSNMKRLSPAPQLG 60
Query: 61 PSSDAHTSYYSESLVHESWFPPRSSLEELHGDANWGEDLRVRRRRGTGGSESSRASGLVG 120
PSSDAHTSYYSESLVHESWFPPRSSLEELHGDANWGEDLRVRRRRGTGGSESSRASGLVG
Sbjct: 61 PSSDAHTSYYSESLVHESWFPPRSSLEELHGDANWGEDLRVRRRRGTGGSESSRASGLVG 120
Query: 121 RKATEDFLGSSSGYSSEDDYVGYSDVDQQSSSSRLRSAVSRAGSLLWMVATSPGRLFRLL 180
RKATEDFLGSSSGYSSEDDYVGYSDVDQQSSSSRLRSAVSRAGSLLWMVATSPGRLFRLL
Sbjct: 121 RKATEDFLGSSSGYSSEDDYVGYSDVDQQSSSSRLRSAVSRAGSLLWMVATSPGRLFRLL 180
Query: 181 YWWAGTTWYRLTTAASLLDVFVLTRRFSSLKTFLWFLLPLLLLTCLTYGAWYFYPYGLQT 240
YWWAGTTWYRLTTAASLLDVFVLTRRFSSLKTFLWFLLPLLLLTCLTYGAWYFYPYGLQT
Sbjct: 181 YWWAGTTWYRLTTAASLLDVFVLTRRFSSLKTFLWFLLPLLLLTCLTYGAWYFYPYGLQT 240
Query: 241 FHPALVSWWAAKDSRRPDEGWEARDSSPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQK 300
FHPALVSWWAAKDSRRPDEGWEARDSSPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQK
Sbjct: 241 FHPALVSWWAAKDSRRPDEGWEARDSSPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQK 300
Query: 301 EAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELS 360
EAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELS
Sbjct: 301 EAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELS 360
Query: 361 ALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAG 420
ALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAG
Sbjct: 361 ALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAG 420
Query: 421 LQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREE 480
LQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREE
Sbjct: 421 LQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREE 480
Query: 481 MQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYS 540
MQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYS
Sbjct: 481 MQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYS 540
Query: 541 EDRIGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGN 600
EDRIGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGN
Sbjct: 541 EDRIGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGN 600
Query: 601 CWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGT 660
CWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGT
Sbjct: 601 CWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGT 660
Query: 661 LLGKFTYDQDGEPIQTFHFQAPTMATYQVVELRILTNWGHPEYTCIYRFRVHGEPAH 717
LLGKFTYDQDGEPIQTFHFQAPTMATYQVVELRILTNWGHPEYTCIYRFRVHGEPAH
Sbjct: 661 LLGKFTYDQDGEPIQTFHFQAPTMATYQVVELRILTNWGHPEYTCIYRFRVHGEPAH 717
>gi|195972890 unc-84 homolog A isoform a [Homo sapiens]
Length = 785
Score = 358 bits (919), Expect = 1e-98
Identities = 269/776 (34%), Positives = 386/776 (49%), Gaps = 104/776 (13%)
Query: 1 MSRRSQRL--TRYSQGDDDGSSSSGGSSVAGSQSTLFKDSPLRTLK-RKSSNMKRLS--- 54
MSRRS RL T + GD + + G+S A S K+ RT K R+S+N S
Sbjct: 51 MSRRSLRLATTACTLGDGEAVGADSGTSSAVS----LKNRAARTTKQRRSTNKSAFSINH 106
Query: 55 PAPQLGPSSDAHTSYYS--------ESLVHESWFPPRSSLEEL-----HGDANWGEDLRV 101
+ Q+ S +H S ++ ESW +++++ GD G +
Sbjct: 107 VSRQVTSSGVSHGGTVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAI 166
Query: 102 RRRRGTG--------GSESSRASGLVGRKATEDFLGSSSG-----YSSEDDYVGYSDVDQ 148
+ G G S S L RK ++ G YS + + Y +
Sbjct: 167 QGNGDVGAAAATAHNGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQKCYFLLQI 226
Query: 149 QSSSSRLRSAVSR-AGSLLWMVATSPGRLFRLLYWWAGTTWYRLTTAASLLDVFVLTRRF 207
+ AVSR A S LW+ +PG+ ++WW G WY+ T S L+VF+LTR
Sbjct: 227 LRRIGAVGQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTLISWLNVFLLTRCL 286
Query: 208 SSLKTFLWFLLPLLLLTC--LTYGAWYFYPYGLQTFHPALVSWWAAKDSRRPDEGWE--- 262
++ FL L+PL LL G F+ +F P L +W + ++R D+ +
Sbjct: 287 RNICKFLVLLIPLFLLLAGLSLRGQGNFF-----SFLPVL-NWASMHRTQRVDDPQDVFK 340
Query: 263 ---ARDSSPHFQAEQRV-----MSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGA 314
+R P Q + MS V L N ++ L++L+ R
Sbjct: 341 PTTSRLKQP-LQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQ 399
Query: 315 PGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLF 374
+GG G S S R+A + RET + +R H ED+
Sbjct: 400 M-EGGAAGPS-----------ASVRDAVGQPP--RETDFMAFHQEHEVRMSHL---EDIL 442
Query: 375 KKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSS 434
K+ S+ + ++Q K + T + E + + L+ +L L+ EL++ ++
Sbjct: 443 GKLREKSEAIQKELEQTKQK----TISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTG 498
Query: 435 VAEEVGLLPQQIQAVRDDVESQFPAWISQFLARG--GGGRVGLLQR--------EEMQAQ 484
+ + AV++ V+ Q + + GG LLQR ++Q
Sbjct: 499 C--------ETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTM 550
Query: 485 LRELESKILT----HVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYS 540
LR+L+ +IL HV+ + EA S + + G G+TE Q IV AL+ YS
Sbjct: 551 LRDLQLQILRNVTHHVSVTKQLPTSEAVVS---AVSEAGASGITEAQARAIVNSALKLYS 607
Query: 541 EDRIGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGN 600
+D+ G+ D+ALESGG S++STRCSETYETKTAL+SLFGIPLWY SQSPRV++QPD++PGN
Sbjct: 608 QDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGN 667
Query: 601 CWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGT 660
CWAF+G QG+ VVRLS I P A TLEH+PK LSP ISSAPKDFA++G + + Q+EG
Sbjct: 668 CWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQ 727
Query: 661 LLGKFTYDQDGEPIQTFH-FQAPTMATYQVVELRILTNWGHPEYTCIYRFRVHGEP 715
LLG+FTYDQDGE +Q F + P +Q+VELRI +NWGHPEYTC+YRFRVHGEP
Sbjct: 728 LLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRFRVHGEP 783
>gi|110227866 unc-84 homolog A isoform b [Homo sapiens]
Length = 702
Score = 346 bits (887), Expect = 5e-95
Identities = 264/762 (34%), Positives = 384/762 (50%), Gaps = 109/762 (14%)
Query: 1 MSRRSQRL--TRYSQGDDDGSSSSGGSSVAGSQSTLFKDSPLRTLK-RKSSNMKRLS--- 54
MSRRS RL T + GD + + G+S A S K+ RT K R+S+N S
Sbjct: 1 MSRRSLRLATTACTLGDGEAVGADSGTSSAVS----LKNRAARTTKQRRSTNKSAFSINH 56
Query: 55 PAPQLGPSSDAHTSYYS--------ESLVHESWFPPRSSLEELHGDANWGEDLRVRRRRG 106
+ Q+ S +H S ++ ESW +++++ G + G DL+
Sbjct: 57 VSRQVTSSGVSHGGTVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDG-DLK------ 109
Query: 107 TGGSESS-RASGLVGRKATEDFLGSS----SGYSSEDDYVGYSDVDQQSSSSRLRSAVSR 161
GG++++ + +G VG A G S S S D + ++ + SR
Sbjct: 110 -GGNKAAIQGNGDVGAAAATAHNGFSCSNCSMLSERKDVL----TAHPAAPGPVSRVYSR 164
Query: 162 AGSLLWMVATSPGRLFRLLYWWAGTTWYRLTTAASLLDVFVLTRRFSSLKTFLWFLLPLL 221
+ W A+ ++WW G WY+ T S L+VF+LTR ++ FL L+PL
Sbjct: 165 DRNQKWKAASG-------VFWWLGIGWYQFVTLISWLNVFLLTRCLRNICKFLVLLIPLF 217
Query: 222 LLTC--LTYGAWYFYPYGLQTFHPALVSWWAAKDSRRPDEGWE------ARDSSPHFQAE 273
LL G F+ +F P L +W + ++R D+ + +R P Q +
Sbjct: 218 LLLAGLSLRGQGNFF-----SFLPVL-NWASMHRTQRVDDPQDVFKPTTSRLKQP-LQGD 270
Query: 274 QRV-----MSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDT 328
MS V L N ++ L++L+ R +GG G S
Sbjct: 271 SEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQM-EGGAAGPS---- 325
Query: 329 LALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARI 388
S R+A + RET + +R H ED+ K+ S+ + +
Sbjct: 326 -------ASVRDAVGQPP--RETDFMAFHQEHEVRMSHL---EDILGKLREKSEAIQKEL 373
Query: 389 QQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQA 448
+Q K + T + E + + L+ +L L+ EL++ ++ + + A
Sbjct: 374 EQTKQK----TISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGC--------ETVDA 421
Query: 449 VRDDVESQFPAWISQFLARG--GGGRVGLLQR--------EEMQAQLRELESKILT---- 494
V++ V+ Q + + GG LLQR ++Q LR+L+ +IL
Sbjct: 422 VQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTH 481
Query: 495 HVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYSEDRIGLADYALESG 554
HV+ + EA S + + G G+TE Q IV AL+ YS+D+ G+ D+ALESG
Sbjct: 482 HVSVTKQLPTSEAVVS---AVSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESG 538
Query: 555 GASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGNCWAFQGPQGFAVVR 614
G S++STRCSETYETKTAL+SLFGIPLWY SQSPRV++QPD++PGNCWAF+G QG+ VVR
Sbjct: 539 GGSILSTRCSETYETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVR 598
Query: 615 LSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGTLLGKFTYDQDGEPI 674
LS I P A TLEH+PK LSP ISSAPKDFA++G + + Q+EG LLG+FTYDQDGE +
Sbjct: 599 LSMMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESL 658
Query: 675 QTFH-FQAPTMATYQVVELRILTNWGHPEYTCIYRFRVHGEP 715
Q F + P +Q+VELRI +NWGHPEYTC+YRFRVHGEP
Sbjct: 659 QMFQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRFRVHGEP 700
>gi|71834870 Sad1 and UNC84 domain containing 1 [Homo sapiens]
Length = 357
Score = 194 bits (492), Expect = 3e-49
Identities = 88/190 (46%), Positives = 126/190 (66%)
Query: 526 EQVHHIVKQALQRYSEDRIGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHS 585
E+V ++V L++ ED++ +ADYAL+S GAS+I SE+Y+ A L GI H
Sbjct: 164 EEVSNLVNYVLKKLREDQVEMADYALKSAGASIIEAGTSESYKNNKAKLYWHGIGFLNHE 223
Query: 586 QSPRVILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKD 645
P +ILQPDV+PG CWAF G QG +++L+ +I PTAVT+EH+ + +SP+ ISSAPK+
Sbjct: 224 MPPDIILQPDVYPGKCWAFPGSQGHTLIKLATKIIPTAVTMEHISEKVSPSGNISSAPKE 283
Query: 646 FAIFGFDEDLQQEGTLLGKFTYDQDGEPIQTFHFQAPTMATYQVVELRILTNWGHPEYTC 705
F+++G + + E LG+F Y++ G +QTF Q V+L I +NWGHP+YTC
Sbjct: 284 FSVYGITKKCEGEEIFLGQFIYNKTGTTVQTFELQHAVSEYLLCVKLNIFSNWGHPKYTC 343
Query: 706 IYRFRVHGEP 715
+YRFRVHG P
Sbjct: 344 LYRFRVHGTP 353
>gi|71834868 Sad1 and UNC84 domain containing 1 [Homo sapiens]
Length = 357
Score = 194 bits (492), Expect = 3e-49
Identities = 88/190 (46%), Positives = 126/190 (66%)
Query: 526 EQVHHIVKQALQRYSEDRIGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHS 585
E+V ++V L++ ED++ +ADYAL+S GAS+I SE+Y+ A L GI H
Sbjct: 164 EEVSNLVNYVLKKLREDQVEMADYALKSAGASIIEAGTSESYKNNKAKLYWHGIGFLNHE 223
Query: 586 QSPRVILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKD 645
P +ILQPDV+PG CWAF G QG +++L+ +I PTAVT+EH+ + +SP+ ISSAPK+
Sbjct: 224 MPPDIILQPDVYPGKCWAFPGSQGHTLIKLATKIIPTAVTMEHISEKVSPSGNISSAPKE 283
Query: 646 FAIFGFDEDLQQEGTLLGKFTYDQDGEPIQTFHFQAPTMATYQVVELRILTNWGHPEYTC 705
F+++G + + E LG+F Y++ G +QTF Q V+L I +NWGHP+YTC
Sbjct: 284 FSVYGITKKCEGEEIFLGQFIYNKTGTTVQTFELQHAVSEYLLCVKLNIFSNWGHPKYTC 343
Query: 706 IYRFRVHGEP 715
+YRFRVHG P
Sbjct: 344 LYRFRVHGTP 353
>gi|11037055 sperm associated antigen 4 [Homo sapiens]
Length = 437
Score = 160 bits (405), Expect = 4e-39
Identities = 84/214 (39%), Positives = 121/214 (56%), Gaps = 3/214 (1%)
Query: 500 QGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYSEDRIGLADYALESGGASVI 559
QG+ ++ A L L KE V V + K QR +ED + DYAL S GAS+
Sbjct: 212 QGQQLQQLQAELD-KLHKE-VSTVRAANSERVAKLVFQRLNEDFVRKPDYALSSVGASID 269
Query: 560 STRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGNCWAFQGPQGFAVVRLSARI 619
+ S Y + W +++ P VIL+P V PGNCWAF+G QG V++L R+
Sbjct: 270 LQKTSHDYADRNTAYFWNRFSFWNYARPPTVILEPHVFPGNCWAFEGDQGQVVIQLPGRV 329
Query: 620 RPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGTLLGKFTYDQDGEPIQTFHF 679
+ + +TL+H P ++ +SAP+DFA+FG + + LGKFT+D + IQTFH
Sbjct: 330 QLSDITLQHPPPSVEHTGGANSAPRDFAVFGL-QVYDETEVSLGKFTFDVEKSEIQTFHL 388
Query: 680 QAPTMATYQVVELRILTNWGHPEYTCIYRFRVHG 713
Q A + V+++IL+NWGHP +TC+YR R HG
Sbjct: 389 QNDPPAAFPKVKIQILSNWGHPRFTCLYRVRAHG 422
>gi|21361792 sperm associated antigen 4-like [Homo sapiens]
Length = 379
Score = 140 bits (354), Expect = 3e-33
Identities = 83/232 (35%), Positives = 127/232 (54%), Gaps = 8/232 (3%)
Query: 485 LRELESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYSEDRI 544
LR + K+ H E+Q R + L LQ+ + ++ I+K Y E
Sbjct: 141 LRLYQEKVRHHSGEIQ--DLRGSMNQLIAKLQEMEAMSDEQKMAQKIMKMIHGDYIEK-- 196
Query: 545 GLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGNCWAF 604
D+AL+S GAS+ S TY + A I LW ++Q P VIL+P+V PGNCWAF
Sbjct: 197 --PDFALKSIGASIDFEHTSVTYNHEKAHSYWNWIQLWNYAQPPDVILEPNVTPGNCWAF 254
Query: 605 QGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGTLLGK 664
+G +G ++L+ ++ + +TL+H+PK +S + ++ +APKDF I+G E +E LG
Sbjct: 255 EGDRGQVTIQLAQKVYLSNLTLQHIPKTISLSGSLDTAPKDFVIYGM-EGSPKEEVFLGA 313
Query: 665 FTYDQDGEPIQTFHFQAPTMATYQVVELRILTNWGHPEYTCIYRFRVHGEPA 716
F + Q IQ F Q + V+++I +NWG+P +TC+YR RVHG A
Sbjct: 314 FQF-QPENIIQMFPLQNQPARAFSAVKVKISSNWGNPGFTCLYRVRVHGSVA 364
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 53.5 bits (127), Expect = 7e-07
Identities = 56/244 (22%), Positives = 109/244 (44%), Gaps = 19/244 (7%)
Query: 271 QAEQRVMSRVHS---LERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHED 327
+ E+R+ R+ S L R E + +++ + ER E R + L +
Sbjct: 523 EEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKRE 582
Query: 328 TLALLEGLVSRREAALKEDFRRETAARI-QEELSALRAEHQQDSEDLFKKIVRASQESEA 386
+ L +E L++ +RE R+ QEE R + ++ E+ ++++++ ++ E
Sbjct: 583 EERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEER 642
Query: 387 RIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQI 446
R QQL+ E Q ++ + +E RLE +L +E ++ +AEE +Q
Sbjct: 643 RQQQLRREQQERREQRLKREEEEE--RLEQRLKREHEE----ERREQELAEE-----EQE 691
Query: 447 QAVRDDVESQFPAWISQFLARGGGGRVGLLQR---EEMQAQLRELESKILTHVAEMQGKS 503
QA R+ ++S+ P W Q + + + R +E Q + +E E K +E+Q +
Sbjct: 692 QA-RERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQE 750
Query: 504 AREA 507
A
Sbjct: 751 EERA 754
Score = 40.0 bits (92), Expect = 0.008
Identities = 47/190 (24%), Positives = 84/190 (44%), Gaps = 19/190 (10%)
Query: 342 ALKEDFRRETAARIQEELSALRAEHQ----QDSEDLFKKIVRASQESEARIQQLKSEWQS 397
AL+E R+E +EE R E + Q+ E +++ + QE E +++ + + +
Sbjct: 894 ALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRR 953
Query: 398 MTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDVES-Q 456
+E Q K+L++ E+QL G + E ++ EE L ++ Q +R++ E +
Sbjct: 954 QERER-QYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR 1012
Query: 457 FPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQ 516
W Q+ + LQ+EE Q LRE K E Q + E L +
Sbjct: 1013 RQEWERQYRKKDE------LQQEEEQL-LREEREKRRLQERERQYREEEE------LQQE 1059
Query: 517 KEGVIGVTEE 526
+E ++G E
Sbjct: 1060 EEQLLGEERE 1069
Score = 36.6 bits (83), Expect = 0.083
Identities = 67/302 (22%), Positives = 114/302 (37%), Gaps = 27/302 (8%)
Query: 252 KDSRRPDEGWEARDSSPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLERLELR 311
++ R E E R + +Q+ + R L R+ E E +++ R E+ E R
Sbjct: 275 EEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEER 334
Query: 312 QGAPGQGGGGGLSHEDTLALLEGLVSRREAALK---EDFRRETAARIQEEL---SALRAE 365
+ Q + E RRE L+ E+ RRE R +++L LR E
Sbjct: 335 REQ--QLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRRE 392
Query: 366 HQQDSEDLFKKIVRASQESEARI-QQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQE 424
Q E ++ + +E + R QQL+ E Q ++ + K + +Q +QE
Sbjct: 393 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQE 452
Query: 425 LAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQ 484
LK+ E ++ Q RD E + W+ L+ EE + Q
Sbjct: 453 ERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLK-------------LEEEERREQ 499
Query: 485 LRELESKILTHVAEM--QGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYSED 542
E ++ E Q +E L L+ E + +E+ +Q L+R E
Sbjct: 500 QERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERR---EQLLKREEEK 556
Query: 543 RI 544
R+
Sbjct: 557 RL 558
Score = 35.8 bits (81), Expect = 0.14
Identities = 52/225 (23%), Positives = 90/225 (40%), Gaps = 33/225 (14%)
Query: 323 LSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQ----QDSEDLFKKIV 378
L ++ L E RR ++ +R E + QEE LR E + Q+ E ++K
Sbjct: 966 LQQKEEQLLGEEPEKRRRQEREKKYREEEELQ-QEEEQLLREEREKRRRQEWERQYRKKD 1024
Query: 379 RASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEE 438
QE E +++ + E + + + Q +EL++ E+QL G ++E + +E
Sbjct: 1025 ELQQEEEQLLRE-EREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKE 1083
Query: 439 VGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAE 498
L ++ Q +R++ E + +R+E + Q RE E L E
Sbjct: 1084 EELQQEEEQLLREEPEKR--------------------RRQERERQCREEEE--LQQEEE 1121
Query: 499 MQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYSEDR 543
+ RE L Q EE+V +Q L+ E R
Sbjct: 1122 QLLREEREKRRRQELERQYR-----EEEEVQQEEEQLLREEPEKR 1161
Score = 34.3 bits (77), Expect = 0.41
Identities = 43/198 (21%), Positives = 80/198 (40%), Gaps = 8/198 (4%)
Query: 350 ETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVK 409
E AR + S L+ Q++ + F+ R +E + ++ K + Q +E S K
Sbjct: 98 EKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEK 157
Query: 410 ELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGG 469
+ RLE + + E ++ EE +Q+Q+ + +FP + L R
Sbjct: 158 Q-ERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPD--EEQLRRRE 214
Query: 470 GGRVGLLQREEMQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQKE-----GVIGVT 524
+ REE Q Q RE + ++ E + + LQ+E +
Sbjct: 215 LLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEE 274
Query: 525 EEQVHHIVKQALQRYSED 542
EEQ+ + +Q L+R ++
Sbjct: 275 EEQLRKLERQELRRERQE 292
Score = 34.3 bits (77), Expect = 0.41
Identities = 49/199 (24%), Positives = 83/199 (41%), Gaps = 33/199 (16%)
Query: 252 KDSRRPDEGWEARDSSPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLERLELR 311
++ R E E RD + +R H ERR + L + ++ ++LE E R
Sbjct: 443 REQRLKREQEERRDWLKREEETER-----HEQERRKQQLKRDQEEERRERWLKLEEEERR 497
Query: 312 QGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELSA---LRAEHQQ 368
+ + E+ RRE LK R+E R+Q+ L + LR E ++
Sbjct: 498 EQQERREQQLRREQEE----------RREQRLK---RQEEEERLQQRLRSEQQLRREQEE 544
Query: 369 DSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSV--KELRRLEDQLAGLQQELA 426
E L K+ E E R++Q + E + ++ + + +E R + +L Q+E
Sbjct: 545 RREQLLKR------EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEE-- 596
Query: 427 ALALKQSSVAEEVGLLPQQ 445
L+Q EEV L Q+
Sbjct: 597 --RLEQRLKREEVERLEQE 613
Score = 32.7 bits (73), Expect = 1.2
Identities = 54/228 (23%), Positives = 90/228 (39%), Gaps = 29/228 (12%)
Query: 338 RREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQES------------- 384
RR+ ++ RRE+ + QEE A R + +++ F +A ++S
Sbjct: 731 RRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPL 790
Query: 385 -EARIQQLKSEWQSMTQESF------QESSVKELRRLEDQLAGLQQE--LAALALKQSSV 435
E R +QL++E + ++ F +E ++ R E +L L++E L Q
Sbjct: 791 REQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQ 850
Query: 436 AEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTH 495
EE GL Q + R + + W Q R L + +Q QLR+ E ++L
Sbjct: 851 EEEDGLQEDQ-ERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRK-EQQLLQE 908
Query: 496 VAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYSEDR 543
E + RE Q EEQ+ +Q L+ E R
Sbjct: 909 EEEELQREEREKRRRQEQERQYR-----EEEQLQQEEEQLLREEREKR 951
Score = 30.4 bits (67), Expect = 6.0
Identities = 43/193 (22%), Positives = 75/193 (38%), Gaps = 14/193 (7%)
Query: 271 QAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLA 330
Q +R L++ E L E ++E R + LE + + L E+
Sbjct: 1044 QERERQYREEEELQQEEEQLLGE-----ERETRRRQELERQYRKEEE-----LQQEEEQL 1093
Query: 331 LLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQ 390
L E RR + R E + QEE LR E ++ ++ R +E + +Q
Sbjct: 1094 LREEPEKRRRQERERQCREEEELQ-QEEEQLLREEREKRRRQELERQYREEEEVQQEEEQ 1152
Query: 391 L---KSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQ 447
L + E + + Q +EL++ E+QL +QE ++ EE ++ Q
Sbjct: 1153 LLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQ 1212
Query: 448 AVRDDVESQFPAW 460
RD+ + W
Sbjct: 1213 RYRDEDQRSDLKW 1225
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 52.0 bits (123), Expect = 2e-06
Identities = 66/276 (23%), Positives = 124/276 (44%), Gaps = 42/276 (15%)
Query: 252 KDSRRPDEGWEARDSSPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLERLELR 311
+D + ++ W+A+ + +AE++ S + SLE + L + + E+ L+RL +
Sbjct: 1200 QDHSKAEDEWKAQVARGRQEAERK-NSLISSLEEEVSILNRQVLEK-EGESKELKRLVMA 1257
Query: 312 QGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQD-- 369
+ Q E+ L LL+ E A E ++ ++EE+ +LR E ++
Sbjct: 1258 ESEKSQ------KLEERLRLLQA-----ETASNSARAAERSSALREEVQSLREEAEKQRV 1306
Query: 370 -SEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAAL 428
SE+L +++ ++ +E Q+LK+ WQ ++ FQ+ +Q L+ L
Sbjct: 1307 ASENLRQELTSQAERAEELGQELKA-WQ---EKFFQK----------------EQALSTL 1346
Query: 429 ALKQSSVAEEVG-LLP-----QQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQ 482
L+ +S V LLP QQ+QA + E + + Q GG R LL+ +
Sbjct: 1347 QLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQREL 1406
Query: 483 AQLRELESKILTHVAEMQGKSAREAAASLSLTLQKE 518
+L L K+ Q A +A+ + L++ K+
Sbjct: 1407 GELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKK 1442
Score = 47.4 bits (111), Expect = 5e-05
Identities = 69/263 (26%), Positives = 108/263 (41%), Gaps = 54/263 (20%)
Query: 345 EDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQ 404
++ R++ A++ E+L + E + E+L KK+ + Q S+ + Q+LK+ Q+ ES Q
Sbjct: 1527 QEERQKLTAQV-EQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAV-QAQGGESQQ 1584
Query: 405 ESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQF 464
E+ +RL+ QL LQ +L+ Q A E L + D + Q
Sbjct: 1585 EA-----QRLQAQLNELQAQLS-----QKEQAAEHYKLQMEKAKTHYDAKKQ-------- 1626
Query: 465 LARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGVT 524
Q +E+Q QLR LE + + K R A L LQ+ G+
Sbjct: 1627 ------------QNQELQEQLRSLEQ------LQKENKELRAEAERLGHELQQAGLKTKE 1668
Query: 525 EEQV-HHIVKQALQRYSEDRIGLADYALESGGASVISTRCSETYETKTA----------- 572
EQ H+ Q R E ++ AD L G ++T ++ E +
Sbjct: 1669 AEQTCRHLTAQV--RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLD 1726
Query: 573 LLSLFGIPLWYHSQSPRVILQPD 595
L G PL S+ PR QPD
Sbjct: 1727 LSCEEGTPLSITSKLPRT--QPD 1747
Score = 41.2 bits (95), Expect = 0.003
Identities = 47/192 (24%), Positives = 89/192 (46%), Gaps = 28/192 (14%)
Query: 271 QAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLA 330
Q EQ H +E + SS+ +++ +L+ + +Q A Q H LA
Sbjct: 541 QQEQASQGLRHQVE--------QLSSSLKQKEQQLKEVAEKQEATRQ------DHAQQLA 586
Query: 331 LL----EGLVSRREAALK--EDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQES 384
E + R+AALK E +E AA++ E+ + + ++ D + V +Q
Sbjct: 587 TAAEEREASLRERDAALKQLEALEKEKAAKL--EILQQQLQVANEARDSAQTSVTQAQRE 644
Query: 385 EARIQQLKSEWQSMTQESFQE--SSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLL 442
+A + + E Q+ + + QE + ++ LE QL QQ+ A ++ VA+E L
Sbjct: 645 KAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQK----ATEKERVAQEKDQL 700
Query: 443 PQQIQAVRDDVE 454
+Q+QA+++ ++
Sbjct: 701 QEQLQALKESLK 712
Score = 33.1 bits (74), Expect = 0.92
Identities = 53/213 (24%), Positives = 83/213 (38%), Gaps = 31/213 (14%)
Query: 339 REAALKEDFRRETAARIQE---ELSALRAE---------HQQDSEDLFKKIVRASQESEA 386
+E A + E A R + +L ALRAE QQ+ D ++ + A + S A
Sbjct: 1099 KEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRA 1158
Query: 387 RIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQI 446
Q +E QE L + LA Q+ELAA K ++ Q+
Sbjct: 1159 ERDSALETLQGQLEEKAQE-----LGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQV 1213
Query: 447 QAVRDDVE------SQFPAWIS----QFLARGGGGR--VGLLQREEMQAQLRELESKILT 494
R + E S +S Q L + G + L+ E ++Q +LE ++
Sbjct: 1214 ARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQ--KLEERLRL 1271
Query: 495 HVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQ 527
AE SAR A S +L + + + E+Q
Sbjct: 1272 LQAETASNSARAAERSSALREEVQSLREEAEKQ 1304
>gi|45439327 periplakin [Homo sapiens]
Length = 1756
Score = 50.1 bits (118), Expect = 7e-06
Identities = 55/226 (24%), Positives = 99/226 (43%), Gaps = 40/226 (17%)
Query: 267 SPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHE 326
S H R+ S ++ ALAA+F+ + RL+ LE Q ++HE
Sbjct: 819 SSHVSKRARLQSPATKVKEEEAALAAKFTEVYAINRQRLQNLEFALNLLRQQPEVEVTHE 878
Query: 327 ------DTLALLEGLVSRREAALKEDFRRETAARI---QEELSALRAEHQQDS------- 370
+ E R+E + + RR+ + QEE+ LR + Q+S
Sbjct: 879 TLQRNRPDSGVEEAWKIRKELDEETERRRQLENEVKSTQEEIWTLRNQGPQESVVRKEVL 938
Query: 371 --------EDLFKKIVRASQESEARIQQLKSEWQSM----------TQESFQESSVKELR 412
E+ F+++ R E + + Q L+ E +++ T++ QE VKE+
Sbjct: 939 KKVPDPVLEESFQQLQRTLAEEQHKNQLLQEELEALQLQLRALEQETRDGGQEYVVKEVL 998
Query: 413 RLE------DQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDD 452
R+E D++ L++EL AL ++ + EV LL Q++ A+ ++
Sbjct: 999 RIEPDRAQADEVLQLREELEALRRQKGAREAEVLLLQQRVAALAEE 1044
Score = 41.6 bits (96), Expect = 0.003
Identities = 69/297 (23%), Positives = 126/297 (42%), Gaps = 47/297 (15%)
Query: 250 AAKDSRRPDEGWEARDSSPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLERLE 309
A KD++ + E FQ + + V SL +L S QK+ + LER
Sbjct: 1278 ALKDTKPQVQTKEVVQEILQFQEDPQTKEEVASLRAKL--------SEEQKKQVDLERER 1329
Query: 310 LRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQD 369
Q E+ +A E +SR +KE ++ R +EE LRAE
Sbjct: 1330 ASQ-------------EEQIARKEEELSR----VKERVVQQEVVRYEEE-PGLRAEASAF 1371
Query: 370 SEDL---FKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELA 426
+E + ++I + E R+Q+ ++E + +E +E + R E ++ LQQ LA
Sbjct: 1372 AESIDVELRQIDKLRAELR-RLQRRRTELERQLEELERERQAR--REAEREVQRLQQRLA 1428
Query: 427 ALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLR 486
AL +++ E+V Q++ +D +++ A + LQ EE Q + +
Sbjct: 1429 ALEQEEAEAREKV-THTQKVVLQQDPQQAREHALLR-------------LQLEEEQHRRQ 1474
Query: 487 ELESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYSEDR 543
LE ++ T ++ E + L+ + G TE+++ + K +L+ S +
Sbjct: 1475 LLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRL-KSSLEEESRSK 1530
>gi|203096856 kinesin family member 7 [Homo sapiens]
Length = 1343
Score = 49.7 bits (117), Expect = 9e-06
Identities = 65/291 (22%), Positives = 119/291 (40%), Gaps = 59/291 (20%)
Query: 279 RVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSR 338
R+ LE+ E + AE S Q++ LE EL+
Sbjct: 744 RIRELEQEAEQVRAELSEG-QRQLRELEGKELQDAG------------------------ 778
Query: 339 REAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSM 398
E + ++FRR AA Q ++ L+ + Q +++V S +SE R+Q+L+ Q M
Sbjct: 779 -ERSRLQEFRRRVAAA-QSQVQVLKEKKQAT-----ERLVSLSAQSEKRLQELERNVQLM 831
Query: 399 TQESFQ-----ESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAV---- 449
Q+ Q ++ RRLE +++ Q + L LK + + + ++I A
Sbjct: 832 RQQQGQLQRRLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKR 891
Query: 450 -------------RDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHV 496
+ +E Q W+ Q + + R L EE+ +L + E+ +
Sbjct: 892 RSGSNGSVVSLEQQQKIEEQ-KKWLDQEMEKVLQQRRAL---EELGEELHKREAILAKKE 947
Query: 497 AEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYSEDRIGLA 547
A MQ K+ E+ S E ++ V+ ++ H+ K+ ++ + R G A
Sbjct: 948 ALMQEKTGLESKRLRSSQALNEDIVRVS-SRLEHLEKELSEKSGQLRQGSA 997
>gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo
sapiens]
Length = 638
Score = 48.5 bits (114), Expect = 2e-05
Identities = 58/290 (20%), Positives = 124/290 (42%), Gaps = 40/290 (13%)
Query: 264 RDSSPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGA-PGQGGGGG 322
+ S+ H QA + + S+ + LE + A+F S A +E L+L + + G
Sbjct: 343 KSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAG 402
Query: 323 LSHEDTLALLEGLVS------------RREAALKEDFRRETAARIQEELSALRAEHQQDS 370
+ ED + S + ++ALKE +E ++++ L+ + +Q
Sbjct: 403 KNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQLKQQE 462
Query: 371 EDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKEL--RRLEDQLAGLQQELAAL 428
ED K++ ++ E R K+E ++ T E +E + L L ++ Q +L A
Sbjct: 463 EDFRKQL----EDEEGR----KAEKENTTAELTEEINKWRLLYEELYNKTKPFQLQLDAF 514
Query: 429 ALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLREL 488
+++ ++ E G +Q+ +RD G L Q+ + +L++
Sbjct: 515 EVEKQALLNEHGAAQEQLNKIRDSYAKLL-------------GHQNLKQKIKHVVKLKDE 561
Query: 489 ESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGV----TEEQVHHIVKQ 534
S++ + V++++ + A++ + L + V+G+ + HH K+
Sbjct: 562 NSQLKSEVSKLRCQLAKKKQSETKLQEELNKVLGIKHFDPSKAFHHESKE 611
Score = 32.7 bits (73), Expect = 1.2
Identities = 46/190 (24%), Positives = 80/190 (42%), Gaps = 28/190 (14%)
Query: 344 KEDF---RRETAARIQEELSALRAE---HQQDSEDLFKKIVRASQESEARIQQLKSEWQS 397
KED RE + E+ L+ + QQ+ E L +K ++ ++ +QQ K S
Sbjct: 214 KEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQI----DSLLQQEKELSSS 269
Query: 398 MTQE--SFQESSVKELRRLEDQLAGLQQELAALALKQ--------------SSVAEEVGL 441
+ Q+ SFQE VKE E++L EL L K+ S AEE+ L
Sbjct: 270 LHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKL 329
Query: 442 LPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAE--M 499
L ++++ ++E A L + E++ AQ ++ + + + +
Sbjct: 330 LEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKL 389
Query: 500 QGKSAREAAA 509
+ S +E AA
Sbjct: 390 ENSSLQEKAA 399
>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
sapiens]
Length = 725
Score = 48.5 bits (114), Expect = 2e-05
Identities = 58/290 (20%), Positives = 124/290 (42%), Gaps = 40/290 (13%)
Query: 264 RDSSPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGA-PGQGGGGG 322
+ S+ H QA + + S+ + LE + A+F S A +E L+L + + G
Sbjct: 430 KSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAG 489
Query: 323 LSHEDTLALLEGLVS------------RREAALKEDFRRETAARIQEELSALRAEHQQDS 370
+ ED + S + ++ALKE +E ++++ L+ + +Q
Sbjct: 490 KNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQLKQQE 549
Query: 371 EDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKEL--RRLEDQLAGLQQELAAL 428
ED K++ ++ E R K+E ++ T E +E + L L ++ Q +L A
Sbjct: 550 EDFRKQL----EDEEGR----KAEKENTTAELTEEINKWRLLYEELYNKTKPFQLQLDAF 601
Query: 429 ALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLREL 488
+++ ++ E G +Q+ +RD G L Q+ + +L++
Sbjct: 602 EVEKQALLNEHGAAQEQLNKIRDSYAKLL-------------GHQNLKQKIKHVVKLKDE 648
Query: 489 ESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGV----TEEQVHHIVKQ 534
S++ + V++++ + A++ + L + V+G+ + HH K+
Sbjct: 649 NSQLKSEVSKLRCQLAKKKQSETKLQEELNKVLGIKHFDPSKAFHHESKE 698
Score = 32.7 bits (73), Expect = 1.2
Identities = 46/190 (24%), Positives = 80/190 (42%), Gaps = 28/190 (14%)
Query: 344 KEDF---RRETAARIQEELSALRAE---HQQDSEDLFKKIVRASQESEARIQQLKSEWQS 397
KED RE + E+ L+ + QQ+ E L +K ++ ++ +QQ K S
Sbjct: 301 KEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQI----DSLLQQEKELSSS 356
Query: 398 MTQE--SFQESSVKELRRLEDQLAGLQQELAALALKQ--------------SSVAEEVGL 441
+ Q+ SFQE VKE E++L EL L K+ S AEE+ L
Sbjct: 357 LHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKL 416
Query: 442 LPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAE--M 499
L ++++ ++E A L + E++ AQ ++ + + + +
Sbjct: 417 LEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKL 476
Query: 500 QGKSAREAAA 509
+ S +E AA
Sbjct: 477 ENSSLQEKAA 486
>gi|217416398 hyaluronan-mediated motility receptor isoform c [Homo
sapiens]
Length = 709
Score = 48.5 bits (114), Expect = 2e-05
Identities = 58/290 (20%), Positives = 124/290 (42%), Gaps = 40/290 (13%)
Query: 264 RDSSPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGA-PGQGGGGG 322
+ S+ H QA + + S+ + LE + A+F S A +E L+L + + G
Sbjct: 414 KSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAG 473
Query: 323 LSHEDTLALLEGLVS------------RREAALKEDFRRETAARIQEELSALRAEHQQDS 370
+ ED + S + ++ALKE +E ++++ L+ + +Q
Sbjct: 474 KNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQLKQQE 533
Query: 371 EDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKEL--RRLEDQLAGLQQELAAL 428
ED K++ ++ E R K+E ++ T E +E + L L ++ Q +L A
Sbjct: 534 EDFRKQL----EDEEGR----KAEKENTTAELTEEINKWRLLYEELYNKTKPFQLQLDAF 585
Query: 429 ALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLREL 488
+++ ++ E G +Q+ +RD G L Q+ + +L++
Sbjct: 586 EVEKQALLNEHGAAQEQLNKIRDSYAKLL-------------GHQNLKQKIKHVVKLKDE 632
Query: 489 ESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGV----TEEQVHHIVKQ 534
S++ + V++++ + A++ + L + V+G+ + HH K+
Sbjct: 633 NSQLKSEVSKLRCQLAKKKQSETKLQEELNKVLGIKHFDPSKAFHHESKE 682
Score = 32.7 bits (73), Expect = 1.2
Identities = 46/190 (24%), Positives = 80/190 (42%), Gaps = 28/190 (14%)
Query: 344 KEDF---RRETAARIQEELSALRAE---HQQDSEDLFKKIVRASQESEARIQQLKSEWQS 397
KED RE + E+ L+ + QQ+ E L +K ++ ++ +QQ K S
Sbjct: 285 KEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQI----DSLLQQEKELSSS 340
Query: 398 MTQE--SFQESSVKELRRLEDQLAGLQQELAALALKQ--------------SSVAEEVGL 441
+ Q+ SFQE VKE E++L EL L K+ S AEE+ L
Sbjct: 341 LHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKL 400
Query: 442 LPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAE--M 499
L ++++ ++E A L + E++ AQ ++ + + + +
Sbjct: 401 LEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKL 460
Query: 500 QGKSAREAAA 509
+ S +E AA
Sbjct: 461 ENSSLQEKAA 470
>gi|217416394 hyaluronan-mediated motility receptor isoform b [Homo
sapiens]
Length = 724
Score = 48.5 bits (114), Expect = 2e-05
Identities = 58/290 (20%), Positives = 124/290 (42%), Gaps = 40/290 (13%)
Query: 264 RDSSPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGA-PGQGGGGG 322
+ S+ H QA + + S+ + LE + A+F S A +E L+L + + G
Sbjct: 429 KSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAG 488
Query: 323 LSHEDTLALLEGLVS------------RREAALKEDFRRETAARIQEELSALRAEHQQDS 370
+ ED + S + ++ALKE +E ++++ L+ + +Q
Sbjct: 489 KNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQLKQQE 548
Query: 371 EDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKEL--RRLEDQLAGLQQELAAL 428
ED K++ ++ E R K+E ++ T E +E + L L ++ Q +L A
Sbjct: 549 EDFRKQL----EDEEGR----KAEKENTTAELTEEINKWRLLYEELYNKTKPFQLQLDAF 600
Query: 429 ALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLREL 488
+++ ++ E G +Q+ +RD G L Q+ + +L++
Sbjct: 601 EVEKQALLNEHGAAQEQLNKIRDSYAKLL-------------GHQNLKQKIKHVVKLKDE 647
Query: 489 ESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGV----TEEQVHHIVKQ 534
S++ + V++++ + A++ + L + V+G+ + HH K+
Sbjct: 648 NSQLKSEVSKLRCQLAKKKQSETKLQEELNKVLGIKHFDPSKAFHHESKE 697
Score = 32.7 bits (73), Expect = 1.2
Identities = 46/190 (24%), Positives = 80/190 (42%), Gaps = 28/190 (14%)
Query: 344 KEDF---RRETAARIQEELSALRAE---HQQDSEDLFKKIVRASQESEARIQQLKSEWQS 397
KED RE + E+ L+ + QQ+ E L +K ++ ++ +QQ K S
Sbjct: 300 KEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQI----DSLLQQEKELSSS 355
Query: 398 MTQE--SFQESSVKELRRLEDQLAGLQQELAALALKQ--------------SSVAEEVGL 441
+ Q+ SFQE VKE E++L EL L K+ S AEE+ L
Sbjct: 356 LHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKL 415
Query: 442 LPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAE--M 499
L ++++ ++E A L + E++ AQ ++ + + + +
Sbjct: 416 LEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKL 475
Query: 500 QGKSAREAAA 509
+ S +E AA
Sbjct: 476 ENSSLQEKAA 485
>gi|115527097 CDC42-binding protein kinase beta [Homo sapiens]
Length = 1711
Score = 47.4 bits (111), Expect = 5e-05
Identities = 60/261 (22%), Positives = 106/261 (40%), Gaps = 29/261 (11%)
Query: 282 SLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREA 341
S ER+L + F + E LE L+++QG G+G G L H+ ++ ++ + ++
Sbjct: 641 SKERKLREHSENFCKQMESE---LEALKVKQG--GRGAGATLEHQQEISKIKSELEKKVL 695
Query: 342 ALKEDFRRETAARIQEELSALRAEHQQDSEDLF--KKIV-----------RASQESEARI 388
+E+ R A+ + E + + H +S L K+I+ E E +
Sbjct: 696 FYEEELVRREASHVLEVKNVKKEVHDSESHQLALQKEILMLKDKLEKSKRERHNEMEEAV 755
Query: 389 QQLKSEWQSMTQESFQESSV-----KELRRLEDQLAG----LQQELAALALKQSSVAEEV 439
+K +++ F E+ ++L D+L L+ EL LA K+ SVA
Sbjct: 756 GTIKDKYERERAMLFDENKKLTAENEKLCSFVDKLTAQNRQLEDELQDLAAKKESVAHWE 815
Query: 440 GLLPQQIQAVRD--DVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVA 497
+ + IQ V D D A S+ R L + + S+ L A
Sbjct: 816 AQIAEIIQWVSDEKDARGYLQALASKMTEELEALRSSSLGSRTLDPLWKVRRSQKLDMSA 875
Query: 498 EMQGKSAREAAASLSLTLQKE 518
++ +SA EA +Q+E
Sbjct: 876 RLELQSALEAEIRAKQLVQEE 896
Score = 38.9 bits (89), Expect = 0.017
Identities = 42/196 (21%), Positives = 86/196 (43%), Gaps = 33/196 (16%)
Query: 262 EARDSSPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRL-ERLELRQGAPGQGGG 320
E + S Q + + +H R L +SN KE +L E +E +
Sbjct: 453 EKLELSRKLQESTQTVQSLHGSSRALS------NSNRDKEIKKLNEEIERLKNKIADSNR 506
Query: 321 GGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQ---QDSEDLFKKI 377
EDT+AL + RE + + L L +H+ Q+ E+L K++
Sbjct: 507 LERQLEDTVALRQ--------------EREDST---QRLRGLEKQHRVVRQEKEELHKQL 549
Query: 378 VRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAE 437
V AS+ +++ ++LK Q ++ +++E L +++A L+ + ++ + E
Sbjct: 550 VEASERLKSQAKELKDAHQQ------RKLALQEFSELNERMAELRAQKQKVSRQLRDKEE 603
Query: 438 EVGLLPQQIQAVRDDV 453
E+ + Q++ A+R ++
Sbjct: 604 EMEVATQKVDAMRQEM 619
Score = 31.2 bits (69), Expect = 3.5
Identities = 40/167 (23%), Positives = 73/167 (43%), Gaps = 18/167 (10%)
Query: 352 AARIQEELSALRAEH--QQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSV- 408
A+++ EEL ALR+ + + L+K VR SQ+ + + E QS + + +
Sbjct: 839 ASKMTEELEALRSSSLGSRTLDPLWK--VRRSQKLD---MSARLELQSALEAEIRAKQLV 893
Query: 409 -KELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQ---------AVRDDVESQFP 458
+ELR+++D L+ +L K + EE+ +L ++++ + D +S F
Sbjct: 894 QEELRKVKDANLTLESKLKDSEAKNRELLEEMEILKKKMEEKFRADTGLKLPDFQDSIFE 953
Query: 459 AWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKSAR 505
+ + LA R +E QA E + +E Q AR
Sbjct: 954 YFNTAPLAHDLTFRTSSASEQETQAPKPEASPSMSVAASEQQEDMAR 1000
>gi|126723390 ankyrin repeat domain 24 [Homo sapiens]
Length = 1146
Score = 46.2 bits (108), Expect = 1e-04
Identities = 73/286 (25%), Positives = 117/286 (40%), Gaps = 47/286 (16%)
Query: 271 QAEQRVMSRVHSLERRLEALAAEFSSNWQK------EAMRL-ERLELRQGAPGQGGGGGL 323
+ E R+ +L +R AAE + K EA RL ER+ +G+ GGGGG
Sbjct: 724 ELETRIRGLEEALRQREREAAAELEAALGKCEAAEAEAGRLRERVREAEGSGASGGGGG- 782
Query: 324 SHEDTLALLEGLVSRREAALKEDFR---RETAARIQEELSALRAEHQQDSEDLFKKIVRA 380
DT L L RE D R E A+ +E A R ++++ L ++
Sbjct: 783 ---DTTQLRAALEQAREDLRDRDSRLRELEAASACLDEARASRLLAEEEARGLRAEL--- 836
Query: 381 SQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLA-----GLQQELAALALKQSSV 435
+Q EAR++Q +EL L +QLA G QQ AA L ++
Sbjct: 837 AQREEARLEQ-----------------SRELEVLREQLATARATGEQQRTAAAELGRARD 879
Query: 436 AEE--VGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQRE--EMQAQLRELESK 491
A E V LP + R + A + + LQ E E++ + LE +
Sbjct: 880 AAEARVAELPAACEEARQGLAELREASEALRQSVVPASEHRRLQEEALELRGRAASLEQE 939
Query: 492 ILT---HVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQ 534
++ A ++ + RE S++L+ + E ++G + V + Q
Sbjct: 940 VVATGKEAARLRAELERERVCSVALS-EHERIVGTLQANVAQLEGQ 984
Score = 37.0 bits (84), Expect = 0.064
Identities = 45/175 (25%), Positives = 81/175 (46%), Gaps = 27/175 (15%)
Query: 322 GLSHEDTLALLEGLVSRREAALKEDFRRETAARI---QEELSALR--AEHQQDSEDLFKK 376
G HE T A E +REA + R A++ +++L LR AE + ++ ++
Sbjct: 989 GRRHEKTSA--EVFQVQREALFMKSERHAAEAQLATAEQQLRGLRTEAERARQAQSRAQE 1046
Query: 377 IVRASQESEARIQQLKSEWQSMTQESFQES----SVKELRRLEDQLAGLQQELAALALKQ 432
+ ++E + +I +L E ++ +E+ +E + E+ L DQ+ LQQ+L A
Sbjct: 1047 ALDKAKEKDKKITELSKEVFNL-KEALKEQPAALATPEVEALRDQVKDLQQQLQEAARDH 1105
Query: 433 SSVAEEVGLLPQQ-IQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLR 486
SSV V L + A++ ++ +SQ +LQ + +QAQ R
Sbjct: 1106 SSV---VALYRSHLLYAIQGQMDEDVQRILSQ-----------ILQMQRLQAQGR 1146
Score = 32.0 bits (71), Expect = 2.0
Identities = 54/263 (20%), Positives = 111/263 (42%), Gaps = 37/263 (14%)
Query: 332 LEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQL 391
LE RR+ E R +EL L E Q++ E L +++ + ++R+ L
Sbjct: 343 LEQHKERRQQESPEASSLHILERQVQELQQLLVERQEEKESLGREV----ESLQSRLSLL 398
Query: 392 KSEWQS----MTQESFQESSVKEL--------RRL----EDQLAGLQQELAALALKQSSV 435
++E ++ +T +E + +L R+L ++ LA LQ+++A L + +
Sbjct: 399 ENERENTSYDVTTLQDEEGELPDLPGAEVLLSRQLSPSAQEHLASLQEQVAVLTRQNQEL 458
Query: 436 AEEVGLL--------PQQIQAVRDDVE-SQFPAWISQF--LARGGGGRVGLLQREEMQAQ 484
E+V +L +++A+ + + + + + ++F L R + L+++E +
Sbjct: 459 MEKVQILENFEKDETQMEVEALAEVIPLALYDSLRAEFDQLRRQHAEALQALRQQETREV 518
Query: 485 LREL-----ESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRY 539
RE ES++ A G + E S++ + G + EE +A +
Sbjct: 519 PREEGAACGESEVAGATATKNGPTHMELNGSVAPETKVNGAETIDEEAAGDETMEA-RTM 577
Query: 540 SEDRIGLADYALESGGASVISTR 562
+ G E+ GA V T+
Sbjct: 578 EAEATGAEATGAEATGAKVTETK 600
>gi|7662176 ProSAPiP1 protein [Homo sapiens]
Length = 673
Score = 45.8 bits (107), Expect = 1e-04
Identities = 52/200 (26%), Positives = 90/200 (45%), Gaps = 31/200 (15%)
Query: 316 GQGGGGGL-----SHEDTLALLEGLVSR------REAALKEDFRRETAARIQ-------- 356
G+GGGGGL S AL++ L R AAL+ + AA Q
Sbjct: 300 GEGGGGGLPFAACSPPSPSALIQELEERLWEKEQEVAALRRSLEQSEAAVAQVLEERQKA 359
Query: 357 --EELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRL 414
EL+ LR + + ++ RA Q + ++ +L+ + + + +E+ + +++ L
Sbjct: 360 WERELAELRQGCSGKLQQVARRAQRAQQGLQLQVLRLQQDKKQLQEEAAR--LMRQREEL 417
Query: 415 EDQLAGLQQELAALALKQSSV-------AEEVGLLPQQIQAVRDDVESQFPAWISQFLAR 467
ED++A Q+E A + A E+ LL QQ++ + DV SQ + I ++
Sbjct: 418 EDKVAACQKEQADFLPRIEETKWEVCQKAGEISLLKQQLKDSQADV-SQKLSEIVGLRSQ 476
Query: 468 GGGGRVGLLQREEMQAQLRE 487
GR L ++EE LR+
Sbjct: 477 LREGRASLREKEEQLLSLRD 496
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 45.4 bits (106), Expect = 2e-04
Identities = 68/287 (23%), Positives = 120/287 (41%), Gaps = 38/287 (13%)
Query: 271 QAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLA 330
+AE+R + + ER E E WQ +A RL L+ + +A
Sbjct: 1609 EAERRAQQQAEA-ERAREEAERELE-RWQLKANEALRLRLQA--------------EEVA 1652
Query: 331 LLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQ 390
+ L KE+ RE R + E A+R + E + + Q +E QQ
Sbjct: 1653 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQE-----LEKQRQLAEGTAQQ 1707
Query: 391 -LKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAV 449
L +E + + + E ++ + LE++LA LQ+E AA K+ + E+ + +++ +
Sbjct: 1708 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL 1767
Query: 450 -----RDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKSA 504
R + ES+ + S+ GR L E + + E+K +AE +A
Sbjct: 1768 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED--AA 1825
Query: 505 REAAASLSLTLQKEGVIG-----VTEEQVHHIVKQA----LQRYSED 542
R+ A + + +K IG TE ++ K+A L+R +ED
Sbjct: 1826 RQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1872
Score = 43.5 bits (101), Expect = 7e-04
Identities = 66/270 (24%), Positives = 110/270 (40%), Gaps = 15/270 (5%)
Query: 285 RRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALK 344
R++E ++++K A LEL G L ++ A LE R+ AA +
Sbjct: 1921 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ-AELEAARQRQLAAEE 1979
Query: 345 EDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQ 404
E RRE R+Q+ L+A E+ + +A+ E R++ E + + + + Q
Sbjct: 1980 ERRRREAEERVQKSLAA---------EEEAARQRKAALEEVERLKAKVEEARRLRERAEQ 2030
Query: 405 ESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQF 464
ES+ + E LQ E A A +E+ QQ Q+V D + + A ++
Sbjct: 2031 ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEA--ARR 2088
Query: 465 LARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKS---AREAAASLSLTLQKEGVI 521
A +RE Q++ + E++ L AE Q ++ A+ AA L ++E
Sbjct: 2089 AAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2148
Query: 522 GVTEEQVHHIVKQALQRYSEDRIGLADYAL 551
EQ KQA E A+ L
Sbjct: 2149 RAQAEQAALRQKQAADAEMEKHKKFAEQTL 2178
Score = 37.4 bits (85), Expect = 0.049
Identities = 62/257 (24%), Positives = 106/257 (41%), Gaps = 35/257 (13%)
Query: 255 RRPDEGWEARDSSPHFQAEQRVMSRVHSLE---RRLEALAAEFSSNWQKEAMRLERLELR 311
RR + +A+ Q E + + + E + +A AAE S +E +R+ RL+L
Sbjct: 1403 RREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLE 1462
Query: 312 QGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSE 371
+GG G L+ L +R E A E +R+ QEE LR + Q +S+
Sbjct: 1463 ATERQRGGAEG--------ELQALRARAEEA--EAQKRQA----QEEAERLRRQVQDESQ 1508
Query: 372 DLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALK 431
R Q ++K+E ++ ++ +++ELR LQ E A L+
Sbjct: 1509 -------RKRQAEVELASRVKAEAEAAREKQRALQALEELR--------LQAEEAERRLR 1553
Query: 432 QSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESK 491
Q+ V E + ++ + E++ + + F + L + AQLRE +
Sbjct: 1554 QAEV-ERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAER 1612
Query: 492 ILTHVAEMQGKSAREAA 508
AE + ARE A
Sbjct: 1613 RAQQQAE--AERAREEA 1627
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 45.4 bits (106), Expect = 2e-04
Identities = 68/287 (23%), Positives = 120/287 (41%), Gaps = 38/287 (13%)
Query: 271 QAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLA 330
+AE+R + + ER E E WQ +A RL L+ + +A
Sbjct: 1613 EAERRAQQQAEA-ERAREEAERELE-RWQLKANEALRLRLQA--------------EEVA 1656
Query: 331 LLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQ 390
+ L KE+ RE R + E A+R + E + + Q +E QQ
Sbjct: 1657 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQE-----LEKQRQLAEGTAQQ 1711
Query: 391 -LKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAV 449
L +E + + + E ++ + LE++LA LQ+E AA K+ + E+ + +++ +
Sbjct: 1712 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL 1771
Query: 450 -----RDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKSA 504
R + ES+ + S+ GR L E + + E+K +AE +A
Sbjct: 1772 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED--AA 1829
Query: 505 REAAASLSLTLQKEGVIG-----VTEEQVHHIVKQA----LQRYSED 542
R+ A + + +K IG TE ++ K+A L+R +ED
Sbjct: 1830 RQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1876
Score = 43.5 bits (101), Expect = 7e-04
Identities = 66/270 (24%), Positives = 110/270 (40%), Gaps = 15/270 (5%)
Query: 285 RRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALK 344
R++E ++++K A LEL G L ++ A LE R+ AA +
Sbjct: 1925 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ-AELEAARQRQLAAEE 1983
Query: 345 EDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQ 404
E RRE R+Q+ L+A E+ + +A+ E R++ E + + + + Q
Sbjct: 1984 ERRRREAEERVQKSLAA---------EEEAARQRKAALEEVERLKAKVEEARRLRERAEQ 2034
Query: 405 ESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQF 464
ES+ + E LQ E A A +E+ QQ Q+V D + + A ++
Sbjct: 2035 ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEA--ARR 2092
Query: 465 LARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKS---AREAAASLSLTLQKEGVI 521
A +RE Q++ + E++ L AE Q ++ A+ AA L ++E
Sbjct: 2093 AAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2152
Query: 522 GVTEEQVHHIVKQALQRYSEDRIGLADYAL 551
EQ KQA E A+ L
Sbjct: 2153 RAQAEQAALRQKQAADAEMEKHKKFAEQTL 2182
Score = 37.4 bits (85), Expect = 0.049
Identities = 62/257 (24%), Positives = 106/257 (41%), Gaps = 35/257 (13%)
Query: 255 RRPDEGWEARDSSPHFQAEQRVMSRVHSLE---RRLEALAAEFSSNWQKEAMRLERLELR 311
RR + +A+ Q E + + + E + +A AAE S +E +R+ RL+L
Sbjct: 1407 RREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLE 1466
Query: 312 QGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSE 371
+GG G L+ L +R E A E +R+ QEE LR + Q +S+
Sbjct: 1467 ATERQRGGAEG--------ELQALRARAEEA--EAQKRQA----QEEAERLRRQVQDESQ 1512
Query: 372 DLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALK 431
R Q ++K+E ++ ++ +++ELR LQ E A L+
Sbjct: 1513 -------RKRQAEVELASRVKAEAEAAREKQRALQALEELR--------LQAEEAERRLR 1557
Query: 432 QSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESK 491
Q+ V E + ++ + E++ + + F + L + AQLRE +
Sbjct: 1558 QAEV-ERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAER 1616
Query: 492 ILTHVAEMQGKSAREAA 508
AE + ARE A
Sbjct: 1617 RAQQQAE--AERAREEA 1631
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 45.4 bits (106), Expect = 2e-04
Identities = 68/287 (23%), Positives = 120/287 (41%), Gaps = 38/287 (13%)
Query: 271 QAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLA 330
+AE+R + + ER E E WQ +A RL L+ + +A
Sbjct: 1609 EAERRAQQQAEA-ERAREEAERELE-RWQLKANEALRLRLQA--------------EEVA 1652
Query: 331 LLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQ 390
+ L KE+ RE R + E A+R + E + + Q +E QQ
Sbjct: 1653 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQE-----LEKQRQLAEGTAQQ 1707
Query: 391 -LKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAV 449
L +E + + + E ++ + LE++LA LQ+E AA K+ + E+ + +++ +
Sbjct: 1708 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL 1767
Query: 450 -----RDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKSA 504
R + ES+ + S+ GR L E + + E+K +AE +A
Sbjct: 1768 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED--AA 1825
Query: 505 REAAASLSLTLQKEGVIG-----VTEEQVHHIVKQA----LQRYSED 542
R+ A + + +K IG TE ++ K+A L+R +ED
Sbjct: 1826 RQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1872
Score = 43.5 bits (101), Expect = 7e-04
Identities = 66/270 (24%), Positives = 110/270 (40%), Gaps = 15/270 (5%)
Query: 285 RRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALK 344
R++E ++++K A LEL G L ++ A LE R+ AA +
Sbjct: 1921 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ-AELEAARQRQLAAEE 1979
Query: 345 EDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQ 404
E RRE R+Q+ L+A E+ + +A+ E R++ E + + + + Q
Sbjct: 1980 ERRRREAEERVQKSLAA---------EEEAARQRKAALEEVERLKAKVEEARRLRERAEQ 2030
Query: 405 ESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQF 464
ES+ + E LQ E A A +E+ QQ Q+V D + + A ++
Sbjct: 2031 ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEA--ARR 2088
Query: 465 LARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKS---AREAAASLSLTLQKEGVI 521
A +RE Q++ + E++ L AE Q ++ A+ AA L ++E
Sbjct: 2089 AAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2148
Query: 522 GVTEEQVHHIVKQALQRYSEDRIGLADYAL 551
EQ KQA E A+ L
Sbjct: 2149 RAQAEQAALRQKQAADAEMEKHKKFAEQTL 2178
Score = 37.4 bits (85), Expect = 0.049
Identities = 62/257 (24%), Positives = 106/257 (41%), Gaps = 35/257 (13%)
Query: 255 RRPDEGWEARDSSPHFQAEQRVMSRVHSLE---RRLEALAAEFSSNWQKEAMRLERLELR 311
RR + +A+ Q E + + + E + +A AAE S +E +R+ RL+L
Sbjct: 1403 RREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLE 1462
Query: 312 QGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSE 371
+GG G L+ L +R E A E +R+ QEE LR + Q +S+
Sbjct: 1463 ATERQRGGAEG--------ELQALRARAEEA--EAQKRQA----QEEAERLRRQVQDESQ 1508
Query: 372 DLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALK 431
R Q ++K+E ++ ++ +++ELR LQ E A L+
Sbjct: 1509 -------RKRQAEVELASRVKAEAEAAREKQRALQALEELR--------LQAEEAERRLR 1553
Query: 432 QSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESK 491
Q+ V E + ++ + E++ + + F + L + AQLRE +
Sbjct: 1554 QAEV-ERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAER 1612
Query: 492 ILTHVAEMQGKSAREAA 508
AE + ARE A
Sbjct: 1613 RAQQQAE--AERAREEA 1627
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 45.4 bits (106), Expect = 2e-04
Identities = 68/287 (23%), Positives = 120/287 (41%), Gaps = 38/287 (13%)
Query: 271 QAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLA 330
+AE+R + + ER E E WQ +A RL L+ + +A
Sbjct: 1577 EAERRAQQQAEA-ERAREEAERELE-RWQLKANEALRLRLQA--------------EEVA 1620
Query: 331 LLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQ 390
+ L KE+ RE R + E A+R + E + + Q +E QQ
Sbjct: 1621 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQE-----LEKQRQLAEGTAQQ 1675
Query: 391 -LKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAV 449
L +E + + + E ++ + LE++LA LQ+E AA K+ + E+ + +++ +
Sbjct: 1676 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL 1735
Query: 450 -----RDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKSA 504
R + ES+ + S+ GR L E + + E+K +AE +A
Sbjct: 1736 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED--AA 1793
Query: 505 REAAASLSLTLQKEGVIG-----VTEEQVHHIVKQA----LQRYSED 542
R+ A + + +K IG TE ++ K+A L+R +ED
Sbjct: 1794 RQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1840
Score = 43.5 bits (101), Expect = 7e-04
Identities = 66/270 (24%), Positives = 110/270 (40%), Gaps = 15/270 (5%)
Query: 285 RRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALK 344
R++E ++++K A LEL G L ++ A LE R+ AA +
Sbjct: 1889 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ-AELEAARQRQLAAEE 1947
Query: 345 EDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQ 404
E RRE R+Q+ L+A E+ + +A+ E R++ E + + + + Q
Sbjct: 1948 ERRRREAEERVQKSLAA---------EEEAARQRKAALEEVERLKAKVEEARRLRERAEQ 1998
Query: 405 ESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQF 464
ES+ + E LQ E A A +E+ QQ Q+V D + + A ++
Sbjct: 1999 ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEA--ARR 2056
Query: 465 LARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKS---AREAAASLSLTLQKEGVI 521
A +RE Q++ + E++ L AE Q ++ A+ AA L ++E
Sbjct: 2057 AAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2116
Query: 522 GVTEEQVHHIVKQALQRYSEDRIGLADYAL 551
EQ KQA E A+ L
Sbjct: 2117 RAQAEQAALRQKQAADAEMEKHKKFAEQTL 2146
Score = 37.4 bits (85), Expect = 0.049
Identities = 62/257 (24%), Positives = 106/257 (41%), Gaps = 35/257 (13%)
Query: 255 RRPDEGWEARDSSPHFQAEQRVMSRVHSLE---RRLEALAAEFSSNWQKEAMRLERLELR 311
RR + +A+ Q E + + + E + +A AAE S +E +R+ RL+L
Sbjct: 1371 RREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLE 1430
Query: 312 QGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSE 371
+GG G L+ L +R E A E +R+ QEE LR + Q +S+
Sbjct: 1431 ATERQRGGAEG--------ELQALRARAEEA--EAQKRQA----QEEAERLRRQVQDESQ 1476
Query: 372 DLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALK 431
R Q ++K+E ++ ++ +++ELR LQ E A L+
Sbjct: 1477 -------RKRQAEVELASRVKAEAEAAREKQRALQALEELR--------LQAEEAERRLR 1521
Query: 432 QSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESK 491
Q+ V E + ++ + E++ + + F + L + AQLRE +
Sbjct: 1522 QAEV-ERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAER 1580
Query: 492 ILTHVAEMQGKSAREAA 508
AE + ARE A
Sbjct: 1581 RAQQQAE--AERAREEA 1595
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 45.4 bits (106), Expect = 2e-04
Identities = 68/287 (23%), Positives = 120/287 (41%), Gaps = 38/287 (13%)
Query: 271 QAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLA 330
+AE+R + + ER E E WQ +A RL L+ + +A
Sbjct: 1746 EAERRAQQQAEA-ERAREEAERELE-RWQLKANEALRLRLQA--------------EEVA 1789
Query: 331 LLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQ 390
+ L KE+ RE R + E A+R + E + + Q +E QQ
Sbjct: 1790 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQE-----LEKQRQLAEGTAQQ 1844
Query: 391 -LKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAV 449
L +E + + + E ++ + LE++LA LQ+E AA K+ + E+ + +++ +
Sbjct: 1845 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL 1904
Query: 450 -----RDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKSA 504
R + ES+ + S+ GR L E + + E+K +AE +A
Sbjct: 1905 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED--AA 1962
Query: 505 REAAASLSLTLQKEGVIG-----VTEEQVHHIVKQA----LQRYSED 542
R+ A + + +K IG TE ++ K+A L+R +ED
Sbjct: 1963 RQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 2009
Score = 43.5 bits (101), Expect = 7e-04
Identities = 66/270 (24%), Positives = 110/270 (40%), Gaps = 15/270 (5%)
Query: 285 RRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALK 344
R++E ++++K A LEL G L ++ A LE R+ AA +
Sbjct: 2058 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ-AELEAARQRQLAAEE 2116
Query: 345 EDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQ 404
E RRE R+Q+ L+A E+ + +A+ E R++ E + + + + Q
Sbjct: 2117 ERRRREAEERVQKSLAA---------EEEAARQRKAALEEVERLKAKVEEARRLRERAEQ 2167
Query: 405 ESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQF 464
ES+ + E LQ E A A +E+ QQ Q+V D + + A ++
Sbjct: 2168 ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEA--ARR 2225
Query: 465 LARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKS---AREAAASLSLTLQKEGVI 521
A +RE Q++ + E++ L AE Q ++ A+ AA L ++E
Sbjct: 2226 AAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2285
Query: 522 GVTEEQVHHIVKQALQRYSEDRIGLADYAL 551
EQ KQA E A+ L
Sbjct: 2286 RAQAEQAALRQKQAADAEMEKHKKFAEQTL 2315
Score = 37.4 bits (85), Expect = 0.049
Identities = 62/257 (24%), Positives = 106/257 (41%), Gaps = 35/257 (13%)
Query: 255 RRPDEGWEARDSSPHFQAEQRVMSRVHSLE---RRLEALAAEFSSNWQKEAMRLERLELR 311
RR + +A+ Q E + + + E + +A AAE S +E +R+ RL+L
Sbjct: 1540 RREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLE 1599
Query: 312 QGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSE 371
+GG G L+ L +R E A E +R+ QEE LR + Q +S+
Sbjct: 1600 ATERQRGGAEG--------ELQALRARAEEA--EAQKRQA----QEEAERLRRQVQDESQ 1645
Query: 372 DLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALK 431
R Q ++K+E ++ ++ +++ELR LQ E A L+
Sbjct: 1646 -------RKRQAEVELASRVKAEAEAAREKQRALQALEELR--------LQAEEAERRLR 1690
Query: 432 QSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESK 491
Q+ V E + ++ + E++ + + F + L + AQLRE +
Sbjct: 1691 QAEV-ERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAER 1749
Query: 492 ILTHVAEMQGKSAREAA 508
AE + ARE A
Sbjct: 1750 RAQQQAE--AERAREEA 1764
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 45.4 bits (106), Expect = 2e-04
Identities = 68/287 (23%), Positives = 120/287 (41%), Gaps = 38/287 (13%)
Query: 271 QAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLA 330
+AE+R + + ER E E WQ +A RL L+ + +A
Sbjct: 1587 EAERRAQQQAEA-ERAREEAERELE-RWQLKANEALRLRLQA--------------EEVA 1630
Query: 331 LLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQ 390
+ L KE+ RE R + E A+R + E + + Q +E QQ
Sbjct: 1631 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQE-----LEKQRQLAEGTAQQ 1685
Query: 391 -LKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAV 449
L +E + + + E ++ + LE++LA LQ+E AA K+ + E+ + +++ +
Sbjct: 1686 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL 1745
Query: 450 -----RDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKSA 504
R + ES+ + S+ GR L E + + E+K +AE +A
Sbjct: 1746 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED--AA 1803
Query: 505 REAAASLSLTLQKEGVIG-----VTEEQVHHIVKQA----LQRYSED 542
R+ A + + +K IG TE ++ K+A L+R +ED
Sbjct: 1804 RQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1850
Score = 43.5 bits (101), Expect = 7e-04
Identities = 66/270 (24%), Positives = 110/270 (40%), Gaps = 15/270 (5%)
Query: 285 RRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALK 344
R++E ++++K A LEL G L ++ A LE R+ AA +
Sbjct: 1899 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ-AELEAARQRQLAAEE 1957
Query: 345 EDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQ 404
E RRE R+Q+ L+A E+ + +A+ E R++ E + + + + Q
Sbjct: 1958 ERRRREAEERVQKSLAA---------EEEAARQRKAALEEVERLKAKVEEARRLRERAEQ 2008
Query: 405 ESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQF 464
ES+ + E LQ E A A +E+ QQ Q+V D + + A ++
Sbjct: 2009 ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEA--ARR 2066
Query: 465 LARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKS---AREAAASLSLTLQKEGVI 521
A +RE Q++ + E++ L AE Q ++ A+ AA L ++E
Sbjct: 2067 AAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2126
Query: 522 GVTEEQVHHIVKQALQRYSEDRIGLADYAL 551
EQ KQA E A+ L
Sbjct: 2127 RAQAEQAALRQKQAADAEMEKHKKFAEQTL 2156
Score = 37.4 bits (85), Expect = 0.049
Identities = 62/257 (24%), Positives = 106/257 (41%), Gaps = 35/257 (13%)
Query: 255 RRPDEGWEARDSSPHFQAEQRVMSRVHSLE---RRLEALAAEFSSNWQKEAMRLERLELR 311
RR + +A+ Q E + + + E + +A AAE S +E +R+ RL+L
Sbjct: 1381 RREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLE 1440
Query: 312 QGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSE 371
+GG G L+ L +R E A E +R+ QEE LR + Q +S+
Sbjct: 1441 ATERQRGGAEG--------ELQALRARAEEA--EAQKRQA----QEEAERLRRQVQDESQ 1486
Query: 372 DLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALK 431
R Q ++K+E ++ ++ +++ELR LQ E A L+
Sbjct: 1487 -------RKRQAEVELASRVKAEAEAAREKQRALQALEELR--------LQAEEAERRLR 1531
Query: 432 QSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESK 491
Q+ V E + ++ + E++ + + F + L + AQLRE +
Sbjct: 1532 QAEV-ERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAER 1590
Query: 492 ILTHVAEMQGKSAREAA 508
AE + ARE A
Sbjct: 1591 RAQQQAE--AERAREEA 1605
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 45.4 bits (106), Expect = 2e-04
Identities = 68/287 (23%), Positives = 120/287 (41%), Gaps = 38/287 (13%)
Query: 271 QAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLA 330
+AE+R + + ER E E WQ +A RL L+ + +A
Sbjct: 1595 EAERRAQQQAEA-ERAREEAERELE-RWQLKANEALRLRLQA--------------EEVA 1638
Query: 331 LLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQ 390
+ L KE+ RE R + E A+R + E + + Q +E QQ
Sbjct: 1639 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQE-----LEKQRQLAEGTAQQ 1693
Query: 391 -LKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAV 449
L +E + + + E ++ + LE++LA LQ+E AA K+ + E+ + +++ +
Sbjct: 1694 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL 1753
Query: 450 -----RDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKSA 504
R + ES+ + S+ GR L E + + E+K +AE +A
Sbjct: 1754 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED--AA 1811
Query: 505 REAAASLSLTLQKEGVIG-----VTEEQVHHIVKQA----LQRYSED 542
R+ A + + +K IG TE ++ K+A L+R +ED
Sbjct: 1812 RQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1858
Score = 43.5 bits (101), Expect = 7e-04
Identities = 66/270 (24%), Positives = 110/270 (40%), Gaps = 15/270 (5%)
Query: 285 RRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALK 344
R++E ++++K A LEL G L ++ A LE R+ AA +
Sbjct: 1907 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ-AELEAARQRQLAAEE 1965
Query: 345 EDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQ 404
E RRE R+Q+ L+A E+ + +A+ E R++ E + + + + Q
Sbjct: 1966 ERRRREAEERVQKSLAA---------EEEAARQRKAALEEVERLKAKVEEARRLRERAEQ 2016
Query: 405 ESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQF 464
ES+ + E LQ E A A +E+ QQ Q+V D + + A ++
Sbjct: 2017 ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEA--ARR 2074
Query: 465 LARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKS---AREAAASLSLTLQKEGVI 521
A +RE Q++ + E++ L AE Q ++ A+ AA L ++E
Sbjct: 2075 AAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2134
Query: 522 GVTEEQVHHIVKQALQRYSEDRIGLADYAL 551
EQ KQA E A+ L
Sbjct: 2135 RAQAEQAALRQKQAADAEMEKHKKFAEQTL 2164
Score = 37.4 bits (85), Expect = 0.049
Identities = 62/257 (24%), Positives = 106/257 (41%), Gaps = 35/257 (13%)
Query: 255 RRPDEGWEARDSSPHFQAEQRVMSRVHSLE---RRLEALAAEFSSNWQKEAMRLERLELR 311
RR + +A+ Q E + + + E + +A AAE S +E +R+ RL+L
Sbjct: 1389 RREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLE 1448
Query: 312 QGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSE 371
+GG G L+ L +R E A E +R+ QEE LR + Q +S+
Sbjct: 1449 ATERQRGGAEG--------ELQALRARAEEA--EAQKRQA----QEEAERLRRQVQDESQ 1494
Query: 372 DLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALK 431
R Q ++K+E ++ ++ +++ELR LQ E A L+
Sbjct: 1495 -------RKRQAEVELASRVKAEAEAAREKQRALQALEELR--------LQAEEAERRLR 1539
Query: 432 QSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESK 491
Q+ V E + ++ + E++ + + F + L + AQLRE +
Sbjct: 1540 QAEV-ERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAER 1598
Query: 492 ILTHVAEMQGKSAREAA 508
AE + ARE A
Sbjct: 1599 RAQQQAE--AERAREEA 1613
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 45.4 bits (106), Expect = 2e-04
Identities = 68/287 (23%), Positives = 120/287 (41%), Gaps = 38/287 (13%)
Query: 271 QAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLA 330
+AE+R + + ER E E WQ +A RL L+ + +A
Sbjct: 1636 EAERRAQQQAEA-ERAREEAERELE-RWQLKANEALRLRLQA--------------EEVA 1679
Query: 331 LLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQ 390
+ L KE+ RE R + E A+R + E + + Q +E QQ
Sbjct: 1680 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQE-----LEKQRQLAEGTAQQ 1734
Query: 391 -LKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAV 449
L +E + + + E ++ + LE++LA LQ+E AA K+ + E+ + +++ +
Sbjct: 1735 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL 1794
Query: 450 -----RDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKSA 504
R + ES+ + S+ GR L E + + E+K +AE +A
Sbjct: 1795 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED--AA 1852
Query: 505 REAAASLSLTLQKEGVIG-----VTEEQVHHIVKQA----LQRYSED 542
R+ A + + +K IG TE ++ K+A L+R +ED
Sbjct: 1853 RQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1899
Score = 43.5 bits (101), Expect = 7e-04
Identities = 66/270 (24%), Positives = 110/270 (40%), Gaps = 15/270 (5%)
Query: 285 RRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALK 344
R++E ++++K A LEL G L ++ A LE R+ AA +
Sbjct: 1948 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ-AELEAARQRQLAAEE 2006
Query: 345 EDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQ 404
E RRE R+Q+ L+A E+ + +A+ E R++ E + + + + Q
Sbjct: 2007 ERRRREAEERVQKSLAA---------EEEAARQRKAALEEVERLKAKVEEARRLRERAEQ 2057
Query: 405 ESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQF 464
ES+ + E LQ E A A +E+ QQ Q+V D + + A ++
Sbjct: 2058 ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEA--ARR 2115
Query: 465 LARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKS---AREAAASLSLTLQKEGVI 521
A +RE Q++ + E++ L AE Q ++ A+ AA L ++E
Sbjct: 2116 AAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2175
Query: 522 GVTEEQVHHIVKQALQRYSEDRIGLADYAL 551
EQ KQA E A+ L
Sbjct: 2176 RAQAEQAALRQKQAADAEMEKHKKFAEQTL 2205
Score = 37.4 bits (85), Expect = 0.049
Identities = 62/257 (24%), Positives = 106/257 (41%), Gaps = 35/257 (13%)
Query: 255 RRPDEGWEARDSSPHFQAEQRVMSRVHSLE---RRLEALAAEFSSNWQKEAMRLERLELR 311
RR + +A+ Q E + + + E + +A AAE S +E +R+ RL+L
Sbjct: 1430 RREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLE 1489
Query: 312 QGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSE 371
+GG G L+ L +R E A E +R+ QEE LR + Q +S+
Sbjct: 1490 ATERQRGGAEG--------ELQALRARAEEA--EAQKRQA----QEEAERLRRQVQDESQ 1535
Query: 372 DLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALK 431
R Q ++K+E ++ ++ +++ELR LQ E A L+
Sbjct: 1536 -------RKRQAEVELASRVKAEAEAAREKQRALQALEELR--------LQAEEAERRLR 1580
Query: 432 QSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESK 491
Q+ V E + ++ + E++ + + F + L + AQLRE +
Sbjct: 1581 QAEV-ERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAER 1639
Query: 492 ILTHVAEMQGKSAREAA 508
AE + ARE A
Sbjct: 1640 RAQQQAE--AERAREEA 1654
>gi|229577000 ecotropic viral integration site 5-like isoform 1
[Homo sapiens]
Length = 805
Score = 44.7 bits (104), Expect = 3e-04
Identities = 71/297 (23%), Positives = 116/297 (39%), Gaps = 70/297 (23%)
Query: 285 RRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLA--LLEGLVSRREAA 342
+RLE A S +E + ++RL Q LA L++G V+R + A
Sbjct: 361 KRLEKEYAAMKSKEMEEQIEIKRLRTENRLLKQRIETLEKESAALADRLIQGQVTRAQEA 420
Query: 343 LKEDFRRETAARIQEELSALRAEHQQDSEDLFK--KIVRASQESEARIQQLKSEWQSMTQ 400
E I+ EL+ +R + +EDL K +R QE + +L ++ S +
Sbjct: 421 -------EENYVIKRELAVVRQQCSSAAEDLQKAQSTIRQLQEQQEN-PRLTEDFVSHLE 472
Query: 401 ESFQESSVKE------LRRLEDQL----------------AGLQQELAALALKQSSVAEE 438
++S ++E LR ++D++ A LQ+EL AL +++
Sbjct: 473 TELEQSRLRETETLGALREMQDKVLDMEKRNSSLPDENNVAQLQEELKALKVREGQAVAS 532
Query: 439 VGLLPQQIQAVRDDVESQFPAWISQFLARGGGGR-------VGLLQREEMQAQLRELESK 491
L Q+Q + D ++ LARGG + VG LQ E M +LRE +
Sbjct: 533 TRELKLQLQELSDTWQAH--------LARGGRWKESPRKLVVGELQDELMSVRLREAQ-- 582
Query: 492 ILTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYSEDRIGLAD 548
A +G+ R+ L E HI + L R +R L +
Sbjct: 583 -----ALAEGRELRQRVVEL--------------ETQDHIHRNLLNRVEAERAALQE 620
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 44.7 bits (104), Expect = 3e-04
Identities = 79/305 (25%), Positives = 124/305 (40%), Gaps = 58/305 (19%)
Query: 279 RVHSLERRLEALAAEFSSNWQKEAM-RLERL---------ELRQGAPGQGGGGGLSHEDT 328
R+ S E +LEALAAE Q +A +L L + + P GGG D+
Sbjct: 1155 RLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGG-----DS 1209
Query: 329 LALLEGLVSRREAALKEDFRRE---TAARIQEELSALRAEHQ-----QDSEDLFKKIVRA 380
+ GL + A + F+R TA + SAL HQ Q + D+ + V+
Sbjct: 1210 APSVWGLEPDQNGA-RSLFKRGPLLTALSAEAVASALHKLHQDLWKTQQTRDVLRDQVQK 1268
Query: 381 SQE----SEARIQQLKSEWQSMTQ------------ESFQESSVKELRRLEDQLAGLQQE 424
+E +EA Q+ +E Q + + E Q S EL L + +A LQ
Sbjct: 1269 LEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSR 1328
Query: 425 LAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQ------R 478
L L++ E LL + + VE A + AR G+L+ R
Sbjct: 1329 LRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVE---ARAQASAAGILEEDLRTAR 1385
Query: 479 EEMQAQLRELES-----KILTHVAEM---QGKSAREAAASLSLTL-QKEGVIGVTEEQVH 529
++ + E+ES + L E+ QGK+ +E A L+ TL ++E + Q+
Sbjct: 1386 SALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQ 1445
Query: 530 HIVKQ 534
+ KQ
Sbjct: 1446 ELEKQ 1450
Score = 42.0 bits (97), Expect = 0.002
Identities = 53/222 (23%), Positives = 104/222 (46%), Gaps = 24/222 (10%)
Query: 338 RREAALKEDFRRETAARIQEELSA-LRAEH---QQDSEDLFKKIVRASQESEARIQQLKS 393
RREA +++ E + EE A L+A+ Q++ E++ KK+ + + EA QL
Sbjct: 653 RREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQL-- 710
Query: 394 EWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDV 453
+ + QE+ ++ V L R + L +E AAL ++ +V + L +Q+Q +
Sbjct: 711 --EQLHQEAKRQEEV--LARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAK 766
Query: 454 E----SQFPAWISQFLARGGGGRVGL------LQREEMQAQLRELESKILTHVAEMQGKS 503
E S F A + G++ + +E +Q ++R L+ ++ T Q +
Sbjct: 767 ELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTE--RSQAEQ 824
Query: 504 AREAAASLSLTLQKEGVIGVTEEQVHH--IVKQALQRYSEDR 543
R+AAA ++EG + +++ H V Q +++ ++R
Sbjct: 825 ERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKER 866
Score = 41.2 bits (95), Expect = 0.003
Identities = 75/303 (24%), Positives = 120/303 (39%), Gaps = 52/303 (17%)
Query: 284 ERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLA-------LLEGLV 336
++ LEAL AE S+ +E R E Q A G+ E L LE
Sbjct: 1939 DQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEAST 1998
Query: 337 SRREAALK----EDFRRETAARIQE-ELSALRAEHQQDSEDLFKKIVRASQE---SEARI 388
+ +A+L + E A RIQE E+ +Q+D + L + + + +E + R
Sbjct: 1999 ATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQERE 2058
Query: 389 QQLKSEWQSMTQESF--------QESSVKELRRL-----EDQLAGLQQELAALALKQSSV 435
Q L+ QE+ QE +E+R L E QL Q+E L L+++
Sbjct: 2059 QLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQ 2118
Query: 436 AEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTH 495
+ LP + + +S + L R + E +QA LR+ E++ +
Sbjct: 2119 RNNLEALPHSHKTSPMEEQSLKLDSLEPRLQR---------ELERLQAALRQTEAREI-- 2167
Query: 496 VAEMQGKSAREAAASLSLTL-QKEGVIGVTEEQVHHIVKQALQRYSE-----DRIGLADY 549
RE A L+L+L Q + + +E + L+R SE D + L
Sbjct: 2168 -------EWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRR 2220
Query: 550 ALE 552
ALE
Sbjct: 2221 ALE 2223
Score = 38.1 bits (87), Expect = 0.029
Identities = 40/174 (22%), Positives = 83/174 (47%), Gaps = 20/174 (11%)
Query: 350 ETAARIQEELSALRAEHQQDSEDLFKKIVRASQES-EARIQQLKSEWQSMTQESFQESSV 408
++ ++ +E L R E +Q E L ++ R + + E ++Q ++ Q Q+ +V
Sbjct: 459 DSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAV 518
Query: 409 KELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQA--VRDDVESQFPAWISQFLA 466
+E RL++ L GL+ KQS E+ L + +++ + ++ Q ++ LA
Sbjct: 519 RERERLQEMLMGLE-------AKQSESLSELITLREALESSHLEGELLRQEQTEVTAALA 571
Query: 467 RGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQKEGV 520
R E+ A+L E+ + T VA+++ + + +A + +L L K G+
Sbjct: 572 RA----------EQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGL 615
Score = 34.7 bits (78), Expect = 0.32
Identities = 32/146 (21%), Positives = 64/146 (43%), Gaps = 9/146 (6%)
Query: 348 RRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESS 407
+ E R++E+ + + A Q E+ R ES QL++E + ++ +
Sbjct: 884 KMELEMRLKEQQTEMEAIQAQREEE------RTQAESALCQMQLETEKERVSLLETLLQT 937
Query: 408 VKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLAR 467
KEL QL L+Q++ LK+ E G+L Q+Q + +++ A
Sbjct: 938 QKELADASQQLERLRQDMKVQKLKEQ---ETTGILQTQLQEAQRELKEAARQHRDDLAAL 994
Query: 468 GGGGRVGLLQREEMQAQLRELESKIL 493
L + ++Q Q+ +L+S+++
Sbjct: 995 QEESSSLLQDKMDLQKQVEDLKSQLV 1020
Score = 33.9 bits (76), Expect = 0.54
Identities = 61/279 (21%), Positives = 115/279 (41%), Gaps = 49/279 (17%)
Query: 271 QAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLER--LELRQGAPGQGGGGGLSHEDT 328
+A + ++H +R E + A +KEA+ E+ LE+R A + +D
Sbjct: 704 EAATTQLEQLHQEAKRQEEVLARAVQ--EKEALVREKAALEVRLQAVER------DRQDL 755
Query: 329 LALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARI 388
L+GL S +E F Q++ S + Q E + + +A + + +
Sbjct: 756 AEQLQGLSSAKELLESSLFEA------QQQNSVIEVTKGQ-LEVQIQTVTQAKEVIQGEV 808
Query: 389 QQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQA 448
+ LK E + ++ QE QLA +QE AL+Q A E +++
Sbjct: 809 RCLKLELDTERSQAEQERDAAAR-----QLAQAEQE-GKTALEQQKAAHE-----KEVNQ 857
Query: 449 VRDDVESQFPAWISQFLARGGGGRVGLLQREEM----------------QAQLRELESKI 492
+R+ E + +W Q LA+ + L+RE+M QAQ E ++
Sbjct: 858 LREKWEKE-RSWHQQELAKA----LESLEREKMELEMRLKEQQTEMEAIQAQREEERTQA 912
Query: 493 LTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHI 531
+ + +MQ ++ +E + L LQ + + +Q+ +
Sbjct: 913 ESALCQMQLETEKERVSLLETLLQTQKELADASQQLERL 951
Score = 32.0 bits (71), Expect = 2.0
Identities = 74/283 (26%), Positives = 110/283 (38%), Gaps = 24/283 (8%)
Query: 271 QAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLER-LELRQGAPGQGGGGGLSHEDTL 329
Q + +V LE RL AE S E L+R L Q + G S E L
Sbjct: 1257 QTRDVLRDQVQKLEERLTDTEAE-KSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESEL 1315
Query: 330 ALL-EGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRA-SQESEAR 387
L E + S + + + +R A +E L A + E L +V A +Q S A
Sbjct: 1316 MELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAG 1375
Query: 388 IQQ---------LKSEWQSMTQESFQESSVKELRRLE-DQLAGLQQELAALALKQSSVAE 437
I + LK + + + E + +++E L+ Q LQ+ LA L + E
Sbjct: 1376 ILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREE 1435
Query: 438 EVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELES--KILTH 495
EV L QIQ + E Q A L + LQ+E Q++ELE +L H
Sbjct: 1436 EVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQE----QIQELEKCRSVLEH 1491
Query: 496 ----VAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQ 534
V E + K + L +E V E Q+ + K+
Sbjct: 1492 LPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKK 1534
Score = 31.2 bits (69), Expect = 3.5
Identities = 51/230 (22%), Positives = 87/230 (37%), Gaps = 43/230 (18%)
Query: 340 EAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMT 399
E +L R + +Q++L R + + + L ++ A + R Q+L++ Q
Sbjct: 1768 ETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQ 1827
Query: 400 QESFQESSVKE-----------------------------LRRLEDQLAGLQQELAALA- 429
Q QE VKE RRLE++LA + + AL
Sbjct: 1828 QAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEE 1887
Query: 430 ----LKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQL 485
L+ S +E LL Q Q E + ++ L +L+ + + +
Sbjct: 1888 VLGDLRAESREQEKALLALQQQCAEQAQEHEVE---TRALQDSWLQAQAVLKERDQELEA 1944
Query: 486 RELESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQA 535
ES+ H Q ++AR A +L L K +EQ H+++QA
Sbjct: 1945 LRAESQSSRH----QEEAARARAEALQEALGKAHAALQGKEQ--HLLEQA 1988
Score = 30.0 bits (66), Expect = 7.8
Identities = 54/253 (21%), Positives = 106/253 (41%), Gaps = 20/253 (7%)
Query: 279 RVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSR 338
RV +LE L L AE S +K + L++ Q + L +D+ + ++
Sbjct: 1881 RVQALEEVLGDLRAE-SREQEKALLALQQQCAEQAQEHEVETRAL--QDSWLQAQAVLKE 1937
Query: 339 REAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKS--EWQ 396
R+ L+ ++R QEE + RAE Q++ ++ ++ +L E
Sbjct: 1938 RDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEAS 1997
Query: 397 SMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQ 456
+ T ++ ++ R+LE+ L + E+ L+ +++ QQ A RD+ E +
Sbjct: 1998 TATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQL----QQALAQRDE-ELR 2052
Query: 457 FPAWISQFLARGGGGRV--GLLQREEMQAQLRELESKILTHVAEMQGKSAREAAASLSLT 514
Q L + RV ++Q ++ Q RE E E++G L+L
Sbjct: 2053 HQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEE--------EIRGLHQSVRELQLTLA 2104
Query: 515 LQKEGVIGVTEEQ 527
+++ ++ + E Q
Sbjct: 2105 QKEQEILELRETQ 2117
>gi|56550043 sarcolemma associated protein [Homo sapiens]
Length = 811
Score = 44.7 bits (104), Expect = 3e-04
Identities = 47/196 (23%), Positives = 94/196 (47%), Gaps = 16/196 (8%)
Query: 324 SHEDTLALLEGLVSRREAALKEDFRRET-AARIQEELSALRAEHQQDSEDLFKKIVRASQ 382
+ ++ L+ + ++ +AA K R+T A +QEEL +RAE ++ +A+
Sbjct: 556 TRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVRAE--------LERWRKAAS 607
Query: 383 ESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLL 442
E E I L++ +Q Q+ ++ +E RL+ +L L++E AL + S+ E LL
Sbjct: 608 EYEKEITSLQNSFQLRCQQC-EDQQREEATRLQGELEKLRKEWNALETECHSLKRENVLL 666
Query: 443 PQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGK 502
++Q ++ + Q L + + R+E++ Q+ L+ + L A++ K
Sbjct: 667 SSELQRQEKELHNS----QKQSLELTSDLSILQMSRKELENQVGSLKEQHLRDSADL--K 720
Query: 503 SAREAAASLSLTLQKE 518
+ A + + +QKE
Sbjct: 721 TLLSKAENQAKDVQKE 736
Score = 35.4 bits (80), Expect = 0.19
Identities = 33/125 (26%), Positives = 63/125 (50%), Gaps = 13/125 (10%)
Query: 345 EDFRRETAARIQEELSALRAEH---QQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQE 401
ED +RE A R+Q EL LR E + + L ++ V S E + + ++L + Q + E
Sbjct: 628 EDQQREEATRLQGELEKLRKEWNALETECHSLKRENVLLSSELQRQEKELHNS-QKQSLE 686
Query: 402 SFQESSVKELRR--LEDQLAGLQQ-------ELAALALKQSSVAEEVGLLPQQIQAVRDD 452
+ S+ ++ R LE+Q+ L++ +L L K + A++V ++ Q V +
Sbjct: 687 LTSDLSILQMSRKELENQVGSLKEQHLRDSADLKTLLSKAENQAKDVQKEYEKTQTVLSE 746
Query: 453 VESQF 457
++ +F
Sbjct: 747 LKLKF 751
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 44.3 bits (103), Expect = 4e-04
Identities = 55/221 (24%), Positives = 101/221 (45%), Gaps = 23/221 (10%)
Query: 336 VSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEW 395
+ R E ALK+ + + +E EHQ E+L I R SE +QQ ++
Sbjct: 747 IQRTEKALKDQINQ--LELLLKERDKHLKEHQAHVENLEADIKR----SEGELQQASAKL 800
Query: 396 QSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDVES 455
+S+Q ++ ++ + E+QLA LQQ+L L ++ + ++V +++A + DV +
Sbjct: 801 DVF--QSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVA----EVEAQKKDVCT 854
Query: 456 QFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKSA-REAAASLSLT 514
+ A Q L+Q+ E Q E + K LT V E + + +E + +
Sbjct: 855 ELDAHKIQV--------QDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQIL 906
Query: 515 LQKEGVIGVTEEQVHHIVKQALQRYS--EDRIGLADYALES 553
++KE +I E ++ Q+ S ED I + + E+
Sbjct: 907 VEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYET 947
Score = 40.8 bits (94), Expect = 0.004
Identities = 54/192 (28%), Positives = 84/192 (43%), Gaps = 43/192 (22%)
Query: 325 HEDTLALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQES 384
H D L G ++ KE R+Q++L LR EHQQ+ E L K+ QE
Sbjct: 1925 HNDLEFKLAGAEREKQKLGKE------IVRLQKDLRMLRKEHQQELEILKKEY---DQER 1975
Query: 385 EARIQQLKSEWQSMTQESFQESSVKEL-RRLEDQLAGLQQELAALALKQS---------- 433
E +I+Q + + E S++K+L R QLA +QEL + +K++
Sbjct: 1976 EEKIKQEQED-----LELKHNSTLKQLMREFNTQLAQKEQEL-EMTIKETINKAQEVEAE 2029
Query: 434 ---SVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELES 490
S EE L ++I DD++ + AR EEM A++R+L+
Sbjct: 2030 LLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAR----------EEEMTAKVRDLQ- 2078
Query: 491 KILTHVAEMQGK 502
T + E+Q K
Sbjct: 2079 ---TQLEELQKK 2087
Score = 37.7 bits (86), Expect = 0.037
Identities = 45/211 (21%), Positives = 100/211 (47%), Gaps = 25/211 (11%)
Query: 327 DTLALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEA 386
+TL + E +++ + +K+ + R Q+E S A E+L K + A + EA
Sbjct: 375 ETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAA-----FEELEKALSTAQKTEEA 429
Query: 387 RIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSS--VAEEVGLLPQ 444
R ++LK+E + + +++S +E L+ +L+ ++QE+ + K S +A+ L +
Sbjct: 430 R-RKLKAEMDEQIK-TIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEK 487
Query: 445 QIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKSA 504
++ ++ + +F +E+M+ L + +S+ L E K
Sbjct: 488 ELARKEQELTKKLQTREREF-------------QEQMKVALEKSQSEYLKISQE---KEQ 531
Query: 505 REAAASLSLTLQKEGVIGVTEEQVHHIVKQA 535
+E+ A L LQK+ ++ +E ++ + ++A
Sbjct: 532 QESLALEELELQKKAILTESENKLRDLQQEA 562
Score = 32.0 bits (71), Expect = 2.0
Identities = 47/236 (19%), Positives = 106/236 (44%), Gaps = 29/236 (12%)
Query: 336 VSRREAALKEDFRRETAA--RIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKS 393
+ ++E+ L+ + + +TA +++ ++ E + +E L + E + +Q+L+
Sbjct: 1509 MEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQ- 1567
Query: 394 EWQSMTQESFQESSVKELRR----LEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAV 449
+Q + +E +++ VKE LE+Q+ ++ EL + V V ++++A+
Sbjct: 1568 HFQELGEE--KDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKAL 1625
Query: 450 RDDVESQFPAWISQFLARGGGGRVG------LLQREEMQAQ--------LRELESKIL-- 493
D +ES+ A +++ L R ++ L Q EE + Q L EL +K+
Sbjct: 1626 EDRLESESAAKLAE-LKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQER 1684
Query: 494 ---THVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYSEDRIGL 546
H+ E + KS + + + + + EQ + +Q+ E++I +
Sbjct: 1685 EREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISV 1740
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.130 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,088,849
Number of Sequences: 37866
Number of extensions: 1226027
Number of successful extensions: 6915
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 458
Number of HSP's that attempted gapping in prelim test: 5927
Number of HSP's gapped (non-prelim): 1236
length of query: 717
length of database: 18,247,518
effective HSP length: 110
effective length of query: 607
effective length of database: 14,082,258
effective search space: 8547930606
effective search space used: 8547930606
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.