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Search of human proteins with 31742490
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31742490 gamma-aminobutyric acid A receptor, gamma 1
precursor [Homo sapiens]
(465 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precurso... 961 0.0
gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform ... 717 0.0
gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform ... 712 0.0
gi|189083762 gamma-aminobutyric acid A receptor, gamma 2 isoform... 691 0.0
gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3 ... 637 0.0
gi|52426761 gamma-aminobutyric acid (GABA) A receptor, epsilon p... 402 e-112
gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precurs... 384 e-106
gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor... 379 e-105
gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5 pr... 375 e-104
gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precurso... 367 e-102
gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 367 e-101
gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 367 e-101
gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 367 e-101
gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 367 e-101
gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 367 e-101
gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 367 e-101
gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1 p... 367 e-101
gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo s... 360 1e-99
gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precurs... 360 1e-99
gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1 p... 283 2e-76
gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2 iso... 281 9e-76
gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3 is... 279 4e-75
gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3 iso... 279 4e-75
gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2 is... 270 3e-72
gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta pre... 266 3e-71
gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo... 265 5e-71
gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens] 263 2e-70
gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens] 263 2e-70
gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens] 263 3e-70
gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens] 263 3e-70
>gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precursor
[Homo sapiens]
Length = 465
Score = 961 bits (2485), Expect = 0.0
Identities = 465/465 (100%), Positives = 465/465 (100%)
Query: 1 MGPLKAFLFSPFLLRSQSRGVRLVFLLLTLHLGNCVDKADDEDDEDLTVNKTWVLAPKIH 60
MGPLKAFLFSPFLLRSQSRGVRLVFLLLTLHLGNCVDKADDEDDEDLTVNKTWVLAPKIH
Sbjct: 1 MGPLKAFLFSPFLLRSQSRGVRLVFLLLTLHLGNCVDKADDEDDEDLTVNKTWVLAPKIH 60
Query: 61 EGDITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWF 120
EGDITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWF
Sbjct: 61 EGDITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWF 120
Query: 121 DSRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTL 180
DSRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTL
Sbjct: 121 DSRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTL 180
Query: 181 RLTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAF 240
RLTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAF
Sbjct: 181 RLTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAF 240
Query: 241 VGLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVP 300
VGLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVP
Sbjct: 241 VGLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVP 300
Query: 301 ARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSN 360
ARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSN
Sbjct: 301 ARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSN 360
Query: 361 QKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGYQCLEGKDCASFFCCFE 420
QKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGYQCLEGKDCASFFCCFE
Sbjct: 361 QKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGYQCLEGKDCASFFCCFE 420
Query: 421 DCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYLYL 465
DCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYLYL
Sbjct: 421 DCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYLYL 465
>gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform 2
precursor [Homo sapiens]
Length = 467
Score = 717 bits (1850), Expect = 0.0
Identities = 346/444 (77%), Positives = 389/444 (87%), Gaps = 5/444 (1%)
Query: 24 VFLLLTLHLGNCVDKADDEDDEDLTVNKTWVLAPKIHEGDITQILNSLLQGYDNKLRPDI 83
+ LLL+L+ G K+DD D ED NKTWVL PK+ EGD+T ILN+LL+GYDNKLRPDI
Sbjct: 27 ILLLLSLYPGFTSQKSDD-DYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRPDI 85
Query: 84 GVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRLKFNSTMKVLMLNSNMVGKI 143
GV+PT+I TD+YVNSIGPV+ INMEYTIDI FAQTW+D RLKFNST+KVL LNSNMVGKI
Sbjct: 86 GVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKI 145
Query: 144 WIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTINAECYLQLHNFPMDEHSCP 203
WIPDTFFRNS+K+DAHWITTPNR+LRIWNDGRVLYTLRLTI+AEC LQLHNFPMDEHSCP
Sbjct: 146 WIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCP 205
Query: 204 LEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGLRNSTEITHTISGDYVIMTIF 263
LEFSSYGYP+ EI Y+WK+ SVEV D + WRLYQF+FVGLRN+TE+ T SGDYV+M+++
Sbjct: 206 LEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVY 265
Query: 264 FDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKS 323
FDLSRRMGYFTIQTYIPC L VVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKS
Sbjct: 266 FDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKS 325
Query: 324 LPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNQKGKTATKDRKLKNKASMTPGLH 383
LPKVSYVTAMDLFVSVCFIFVF+AL+EYGTLHYF SN+K + KD+K KN A T +
Sbjct: 326 LPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRK-PSKDKDKKKKNPAP-TIDIR 383
Query: 384 PGSTLIPMNNISVPQE--DDYGYQCLEGKDCASFFCCFEDCRTGSWREGRIHIRIAKIDS 441
P S I MNN + QE ++YGY+CL+GKDCASFFCCFEDCRTG+WR GRIHIRIAK+DS
Sbjct: 384 PRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDS 443
Query: 442 YSRIFFPTAFALFNLVYWVGYLYL 465
Y+RIFFPTAF LFNLVYWV YLYL
Sbjct: 444 YARIFFPTAFCLFNLVYWVSYLYL 467
>gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform 1
precursor [Homo sapiens]
Length = 475
Score = 712 bits (1839), Expect = 0.0
Identities = 345/451 (76%), Positives = 389/451 (86%), Gaps = 11/451 (2%)
Query: 24 VFLLLTLHLGNCVDKADDEDDEDLTVNKTWVLAPKIHEGDITQILNSLLQGYDNKLRPDI 83
+ LLL+L+ G K+DD D ED NKTWVL PK+ EGD+T ILN+LL+GYDNKLRPDI
Sbjct: 27 ILLLLSLYPGFTSQKSDD-DYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRPDI 85
Query: 84 GVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRLKFNSTMKVLMLNSNMVGKI 143
GV+PT+I TD+YVNSIGPV+ INMEYTIDI FAQTW+D RLKFNST+KVL LNSNMVGKI
Sbjct: 86 GVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKI 145
Query: 144 WIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTINAECYLQLHNFPMDEHSCP 203
WIPDTFFRNS+K+DAHWITTPNR+LRIWNDGRVLYTLRLTI+AEC LQLHNFPMDEHSCP
Sbjct: 146 WIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCP 205
Query: 204 LEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGLRNSTEITHTISGDYVIMTIF 263
LEFSSYGYP+ EI Y+WK+ SVEV D + WRLYQF+FVGLRN+TE+ T SGDYV+M+++
Sbjct: 206 LEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVY 265
Query: 264 FDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKS 323
FDLSRRMGYFTIQTYIPC L VVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKS
Sbjct: 266 FDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKS 325
Query: 324 LPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNQKGKTATKDRKLKNK-------A 376
LPKVSYVTAMDLFVSVCFIFVF+AL+EYGTLHYF SN+K + KD+K KN
Sbjct: 326 LPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRK-PSKDKDKKKKNPLLRMFSFK 384
Query: 377 SMTPGLHPGSTLIPMNNISVPQE--DDYGYQCLEGKDCASFFCCFEDCRTGSWREGRIHI 434
+ T + P S I MNN + QE ++YGY+CL+GKDCASFFCCFEDCRTG+WR GRIHI
Sbjct: 385 APTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHI 444
Query: 435 RIAKIDSYSRIFFPTAFALFNLVYWVGYLYL 465
RIAK+DSY+RIFFPTAF LFNLVYWV YLYL
Sbjct: 445 RIAKMDSYARIFFPTAFCLFNLVYWVSYLYL 475
>gi|189083762 gamma-aminobutyric acid A receptor, gamma 2 isoform 3
precursor [Homo sapiens]
Length = 515
Score = 691 bits (1783), Expect = 0.0
Identities = 344/491 (70%), Positives = 389/491 (79%), Gaps = 51/491 (10%)
Query: 24 VFLLLTLHLGNCVDKADDEDDEDLTVNKTWVLAPKIHEGDITQILNSLLQGYDNKLRPDI 83
+ LLL+L+ G K+DD D ED NKTWVL PK+ EGD+T ILN+LL+GYDNKLRPDI
Sbjct: 27 ILLLLSLYPGFTSQKSDD-DYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRPDI 85
Query: 84 GVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRLKFNSTMKVLMLNSNMVGKI 143
GV+PT+I TD+YVNSIGPV+ INMEYTIDI FAQTW+D RLKFNST+KVL LNSNMVGKI
Sbjct: 86 GVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKI 145
Query: 144 WIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTINAECYLQLHNFPMDEHSCP 203
WIPDTFFRNS+K+DAHWITTPNR+LRIWNDGRVLYTLRLTI+AEC LQLHNFPMDEHSCP
Sbjct: 146 WIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCP 205
Query: 204 LEFSSY----------------------------------------GYPKNEIEYKWKKP 223
LEFSS+ GYP+ EI Y+WK+
Sbjct: 206 LEFSSWSRSIAQAGMCSGVISAHYSLRFWGSTDPPTLASRVAGISDGYPREEIVYQWKRS 265
Query: 224 SVEVADPKYWRLYQFAFVGLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCIL 283
SVEV D + WRLYQF+FVGLRN+TE+ T SGDYV+M+++FDLSRRMGYFTIQTYIPC L
Sbjct: 266 SVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTL 325
Query: 284 TVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIF 343
VVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIF
Sbjct: 326 IVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIF 385
Query: 344 VFAALMEYGTLHYFTSNQKGKTATKDRKLKNK-------ASMTPGLHPGSTLIPMNNISV 396
VF+AL+EYGTLHYF SN+K + KD+K KN + T + P S I MNN +
Sbjct: 386 VFSALVEYGTLHYFVSNRK-PSKDKDKKKKNPLLRMFSFKAPTIDIRPRSATIQMNNATH 444
Query: 397 PQE--DDYGYQCLEGKDCASFFCCFEDCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALF 454
QE ++YGY+CL+GKDCASFFCCFEDCRTG+WR GRIHIRIAK+DSY+RIFFPTAF LF
Sbjct: 445 LQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLF 504
Query: 455 NLVYWVGYLYL 465
NLVYWV YLYL
Sbjct: 505 NLVYWVSYLYL 515
>gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3
[Homo sapiens]
Length = 467
Score = 637 bits (1644), Expect = 0.0
Identities = 307/447 (68%), Positives = 361/447 (80%), Gaps = 19/447 (4%)
Query: 38 KADDEDDEDLTVNKTWVLAPKIHEGDITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVN 97
K ++++ ED + N+ WVLAPK + D+T ILN LL+ YD KLRPDIG++PTVI+ D+YVN
Sbjct: 21 KVEEDEYEDSSSNQKWVLAPKSQDTDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVN 80
Query: 98 SIGPVDPINMEYTIDIIFAQTWFDSRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSD 157
SIGPV INMEY IDI FAQTW DSRL+FNSTMK+L LNSNMVG IWIPDT FRNS+ ++
Sbjct: 81 SIGPVSSINMEYQIDIFFAQTWTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAE 140
Query: 158 AHWITTPNRLLRIWNDGRVLYTLRLTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIE 217
AHWITTPN+LLRIWNDG++LYTLRLTINAEC LQLHNFPMDEHSCPL FSSYGYPK E+
Sbjct: 141 AHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMI 200
Query: 218 YKWKKPSVEVADPKYWRLYQFAFVGLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQT 277
Y+W+K SVE AD K WRLYQF F+GLRN+TEI T +GDYV+MTI+F+LSRRMGYFTIQT
Sbjct: 201 YRWRKNSVEAADQKSWRLYQFDFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQT 260
Query: 278 YIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFV 337
YIPCILTVVLSWVSFWI KDA PART+LGITTVLTMTTLSTIARKSLP+VSYVTAMDLFV
Sbjct: 261 YIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFV 320
Query: 338 SVCFIFVFAALMEYGTLHYFTSNQKGKTATKDRKL-----------------KNKASMTP 380
+VCF+FVFAALMEY TL+Y++S +K T K L + S+
Sbjct: 321 TVCFLFVFAALMEYATLNYYSSCRKPTTTKKTTSLLHPDSSRWIPERISLQAPSNYSLLD 380
Query: 381 GLHPGSTLIPMNNISVPQ--EDDYGYQCLEGKDCASFFCCFEDCRTGSWREGRIHIRIAK 438
P + +I +NN Q ED Y+CL+GKDC SFFCC+E+C++GSWR+GRIHI I +
Sbjct: 381 MRPPPTAMITLNNSVYWQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRKGRIHIDILE 440
Query: 439 IDSYSRIFFPTAFALFNLVYWVGYLYL 465
+DSYSR+FFPT+F LFNLVYWVGYLYL
Sbjct: 441 LDSYSRVFFPTSFLLFNLVYWVGYLYL 467
>gi|52426761 gamma-aminobutyric acid (GABA) A receptor, epsilon
precursor [Homo sapiens]
Length = 506
Score = 402 bits (1032), Expect = e-112
Identities = 195/437 (44%), Positives = 283/437 (64%), Gaps = 34/437 (7%)
Query: 63 DITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDS 122
+ ++ILN++L YD+KLRP IG +PTV+ ++ VNS+GP+ ++MEYTIDIIF+QTW+D
Sbjct: 70 EASRILNTILSNYDHKLRPGIGEKPTVVTVEISVNSLGPLSILDMEYTIDIIFSQTWYDE 129
Query: 123 RLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRL 182
RL +N T + L+LN N+V ++WIPDTFFRNS+++ H IT PN+++RI+ DG+VLYT+R+
Sbjct: 130 RLCYNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRM 189
Query: 183 TINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVG 242
TI+A C L + FPMD HSCPL FSS+ YP+NE+ YKW+ +E+ + W+L+QF F G
Sbjct: 190 TIDAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTG 249
Query: 243 LRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPAR 302
+ N TEI T GD+++MTIFF++SRR GY Q Y+P +T +LSWVSFWI ++ PAR
Sbjct: 250 VSNKTEIITTPVGDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPAR 309
Query: 303 TSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNQ- 361
TSLGIT+VLTMTTL T +RK+ P+VSY+TA+D ++++CF+F F AL+E+ L++ NQ
Sbjct: 310 TSLGITSVLTMTTLGTFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFLIYNQT 369
Query: 362 KGKTATKDR--KLKNKASMTPGLH-------------------PGSTLIPMNNISVPQED 400
K + K R ++ ++A GS + S Q
Sbjct: 370 KAHASPKLRHPRINSRAHARTRARSRACARQHQEAFVCQIVTTEGSDGEERPSCSAQQPP 429
Query: 401 DYG-----------YQCLEG-KDCASFFCCFEDCRTGSWREGRIHIRIAKIDSYSRIFFP 448
G C E K +FC DC +W++GR+ I + ++D+YSR+ FP
Sbjct: 430 SPGSPEGPRSLCSKLACCEWCKRFKKYFCMVPDCEGSTWQQGRLCIHVYRLDNYSRVVFP 489
Query: 449 TAFALFNLVYWVGYLYL 465
F FN++YW+ L L
Sbjct: 490 VTFFFFNVLYWLVCLNL 506
>gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precursor
[Homo sapiens]
Length = 453
Score = 384 bits (985), Expect = e-106
Identities = 206/417 (49%), Positives = 267/417 (64%), Gaps = 22/417 (5%)
Query: 63 DITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDS 122
++++IL++LL+GYDN+LRP G T ++TD+YV S GPV + MEYT+D+ F QTW D
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 123 RLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRL 182
RLKF ++L LN+ MV KIW PDTFFRN +KS AH +TTPN+L RI +G +LYT+RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 183 TINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKP---SVEVADPKYWRLYQFA 239
TINA+C ++L NFPMD H+CPL+F SY YPK+EI Y WKK SVEV + L Q+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESS-SLLQYD 209
Query: 240 FVGLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAV 299
+G S+E + +G+YVIMT++F L R+MGYF IQ Y PCI+TV+LS VSFWINK++V
Sbjct: 210 LIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESV 269
Query: 300 PARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTS 359
PART GITTVLTMTTLS AR SLPKVSY TAMD F++VCF FVF+AL+E+ ++YFT+
Sbjct: 270 PARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTN 329
Query: 360 NQKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGYQCLEGKDCASFFCCF 419
Q T+ K K + + P + P+ V D + +
Sbjct: 330 LQ-----TQKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLPIVSS 384
Query: 420 EDCRTGSWREGRIHIR-------------IAKIDSYSRIFFPTAFALFNLVYWVGYL 463
+ R + +KID YSRI FP AFA FNLVYWV YL
Sbjct: 385 SEANKVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVYL 441
>gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor
[Homo sapiens]
Length = 492
Score = 379 bits (974), Expect = e-105
Identities = 196/413 (47%), Positives = 269/413 (65%), Gaps = 15/413 (3%)
Query: 65 TQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRL 124
T+IL+ LL GYDN+LRP +G T ++TD+YV S GPV +MEYTID+ F QTW D RL
Sbjct: 68 TRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERL 127
Query: 125 KFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTI 184
KF+ MK+L LN+ + KIW PDTFF N +KS AH +TTPN+LLR+ ++G +LYT+RLTI
Sbjct: 128 KFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLTI 187
Query: 185 NAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKW---KKPSVEVADPKYWRLYQFAFV 241
+AEC + L +FPMD H+CPL+F SY Y E+ Y W K SVEVA RL Q+ +
Sbjct: 188 HAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGS-RLNQYDLL 246
Query: 242 GLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPA 301
G TEI + +G+YV+MT F L R++GYF IQTY+PCI+TV+LS VSFW+N+++VPA
Sbjct: 247 GHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 306
Query: 302 RTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNQ 361
RT G+TTVLTMTTLS AR SLPKV+Y TAMD F++VC+ FVF+AL+E+ T++YFT
Sbjct: 307 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRS 366
Query: 362 ---KGKTATKDRKLKNKASMTPGLHPGSTLIPMNN---ISVPQEDDYGYQCLEGKDCASF 415
+GK + ++K K P +T + I++ ++ ++ AS
Sbjct: 367 WAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAPSASS 426
Query: 416 FCCFEDCRTGSW-----REGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYL 463
++ E + + ++K+D SRI FP FA+FNLVYW Y+
Sbjct: 427 TPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYV 479
>gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5
precursor [Homo sapiens]
Length = 462
Score = 375 bits (962), Expect = e-104
Identities = 196/404 (48%), Positives = 259/404 (64%), Gaps = 9/404 (2%)
Query: 65 TQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRL 124
T+IL+ LL GYDN+LRP +G R T + TD+YV S GPV MEYTID+ F Q+W D RL
Sbjct: 50 TRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERL 109
Query: 125 KFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTI 184
+F M+ L LN+ + KIW PDTFF N +KS AH +TTPN+LLR+ +DG +LYT+RLTI
Sbjct: 110 RFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTI 169
Query: 185 NAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVE--VADPKYWRLYQFAFVG 242
+AEC +QL +FPMD H+CPL+F SY YP +E+ Y W S + V RL Q+ +G
Sbjct: 170 SAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMG 229
Query: 243 LRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPAR 302
TE T +G+Y IMT F L R++GYF IQTY+PCI+TV+LS VSFW+N+++VPAR
Sbjct: 230 QTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 289
Query: 303 TSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSN-- 360
T G+TTVLTMTTLS AR SLPKV+Y TAMD F++VC+ FVF+AL+E+ T++YFT
Sbjct: 290 TVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGW 349
Query: 361 -QKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGYQCLEGKDCASFFCCF 419
GK A + K+K K + L+ + +S P + S
Sbjct: 350 AWDGKKALEAAKIKKKREVI--LNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKP 407
Query: 420 EDCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYL 463
+ +T + + + I+KID SRI FP F FNLVYW YL
Sbjct: 408 SEEKTSESK--KTYNSISKIDKMSRIVFPVLFGTFNLVYWATYL 449
>gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precursor
[Homo sapiens]
Length = 554
Score = 367 bits (943), Expect = e-102
Identities = 185/370 (50%), Positives = 251/370 (67%), Gaps = 12/370 (3%)
Query: 26 LLLTLHLGNCVDKADDEDDEDLTVNKTWVLAPKIHEGDITQILNSLLQGYDNKLRPDIGV 85
LL L L C++++ ++ ++ K+ + T+IL+SLL GYDN+LRP G
Sbjct: 20 LLRFLCLAVCLNESPGQNQKE----------EKLCTENFTRILDSLLDGYDNRLRPGFGG 69
Query: 86 RPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRLKFNSTMKVLMLNSNMVGKIWI 145
T ++TD+YV S GPV + MEYT+D+ F QTW D RLK++ +++L LN+ MV K+W
Sbjct: 70 PVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKYDGPIEILRLNNMMVTKVWT 129
Query: 146 PDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTINAECYLQLHNFPMDEHSCPLE 205
PDTFFRN +KS +H +T PN+L RI +G +LYT+RLTI+AEC ++L +FPMD H+CPL+
Sbjct: 130 PDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLK 189
Query: 206 FSSYGYPKNEIEYKWKK-PSVEVADPK-YWRLYQFAFVGLRNSTEITHTISGDYVIMTIF 263
F SY YPK+E+ Y W K P V PK L Q+ +G S+E +I+G+Y++MT++
Sbjct: 190 FGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLIGQTVSSETIKSITGEYIVMTVY 249
Query: 264 FDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKS 323
F L R+MGYF IQTYIPCI+TV+LS VSFWINK++VPART GITTVLTMTTLS AR S
Sbjct: 250 FHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHS 309
Query: 324 LPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNQKGKTATKDRKLKNKASMTPGLH 383
LPKVSY TAMD F++VCF FVF+AL+E+ ++YFT+ Q K K K + P
Sbjct: 310 LPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNIQMEKAKRKTSKPPQEVPAAPVQR 369
Query: 384 PGSTLIPMNN 393
P+ N
Sbjct: 370 EKHPEAPLQN 379
Score = 42.7 bits (99), Expect = 7e-04
Identities = 17/27 (62%), Positives = 20/27 (74%)
Query: 437 AKIDSYSRIFFPTAFALFNLVYWVGYL 463
+KID Y+RI FP F FN+VYWV YL
Sbjct: 516 SKIDKYARILFPVTFGAFNMVYWVVYL 542
>gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 367 bits (942), Expect = e-101
Identities = 195/412 (47%), Positives = 256/412 (62%), Gaps = 24/412 (5%)
Query: 65 TQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRL 124
T+IL+ LL GYDN+LRP +G R T ++TD++V S GPV +MEYTID+ F Q+W D RL
Sbjct: 43 TRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 125 KFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTI 184
KF M VL LN+ M KIW PDTFF N +KS AH +T PN+LLRI DG +LYT+RLT+
Sbjct: 103 KFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTV 162
Query: 185 NAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKP---SVEVADPKYWRLYQFAFV 241
AEC + L +FPMD H+CPL+F SY Y + E+ Y+W + SV VA+ RL Q+ +
Sbjct: 163 RAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-RLNQYDLL 221
Query: 242 GLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPA 301
G + I + +G+YV+MT F L R++GYF IQTY+PCI+TV+LS VSFW+N+++VPA
Sbjct: 222 GQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 281
Query: 302 RTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSN- 360
RT G+TTVLTMTTLS AR SLPKV+Y TAMD F++VC+ FVF+AL+E+ T++YFT
Sbjct: 282 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 341
Query: 361 --QKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGYQCLEGKDCASFFCC 418
GK+ ++ K K LI NN P Y G +
Sbjct: 342 YAWDGKSVVPEKPKKVK----------DPLIKKNNTYAPTATSYTPNLARGDPGLATIAK 391
Query: 419 FEDC-------RTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYL 463
T + ++KID SRI FP F +FNLVYW YL
Sbjct: 392 SATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYL 443
>gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 367 bits (942), Expect = e-101
Identities = 195/412 (47%), Positives = 256/412 (62%), Gaps = 24/412 (5%)
Query: 65 TQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRL 124
T+IL+ LL GYDN+LRP +G R T ++TD++V S GPV +MEYTID+ F Q+W D RL
Sbjct: 43 TRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 125 KFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTI 184
KF M VL LN+ M KIW PDTFF N +KS AH +T PN+LLRI DG +LYT+RLT+
Sbjct: 103 KFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTV 162
Query: 185 NAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKP---SVEVADPKYWRLYQFAFV 241
AEC + L +FPMD H+CPL+F SY Y + E+ Y+W + SV VA+ RL Q+ +
Sbjct: 163 RAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-RLNQYDLL 221
Query: 242 GLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPA 301
G + I + +G+YV+MT F L R++GYF IQTY+PCI+TV+LS VSFW+N+++VPA
Sbjct: 222 GQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 281
Query: 302 RTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSN- 360
RT G+TTVLTMTTLS AR SLPKV+Y TAMD F++VC+ FVF+AL+E+ T++YFT
Sbjct: 282 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 341
Query: 361 --QKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGYQCLEGKDCASFFCC 418
GK+ ++ K K LI NN P Y G +
Sbjct: 342 YAWDGKSVVPEKPKKVK----------DPLIKKNNTYAPTATSYTPNLARGDPGLATIAK 391
Query: 419 FEDC-------RTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYL 463
T + ++KID SRI FP F +FNLVYW YL
Sbjct: 392 SATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYL 443
>gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 367 bits (942), Expect = e-101
Identities = 195/412 (47%), Positives = 256/412 (62%), Gaps = 24/412 (5%)
Query: 65 TQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRL 124
T+IL+ LL GYDN+LRP +G R T ++TD++V S GPV +MEYTID+ F Q+W D RL
Sbjct: 43 TRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 125 KFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTI 184
KF M VL LN+ M KIW PDTFF N +KS AH +T PN+LLRI DG +LYT+RLT+
Sbjct: 103 KFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTV 162
Query: 185 NAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKP---SVEVADPKYWRLYQFAFV 241
AEC + L +FPMD H+CPL+F SY Y + E+ Y+W + SV VA+ RL Q+ +
Sbjct: 163 RAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-RLNQYDLL 221
Query: 242 GLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPA 301
G + I + +G+YV+MT F L R++GYF IQTY+PCI+TV+LS VSFW+N+++VPA
Sbjct: 222 GQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 281
Query: 302 RTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSN- 360
RT G+TTVLTMTTLS AR SLPKV+Y TAMD F++VC+ FVF+AL+E+ T++YFT
Sbjct: 282 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 341
Query: 361 --QKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGYQCLEGKDCASFFCC 418
GK+ ++ K K LI NN P Y G +
Sbjct: 342 YAWDGKSVVPEKPKKVK----------DPLIKKNNTYAPTATSYTPNLARGDPGLATIAK 391
Query: 419 FEDC-------RTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYL 463
T + ++KID SRI FP F +FNLVYW YL
Sbjct: 392 SATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYL 443
>gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 367 bits (942), Expect = e-101
Identities = 195/412 (47%), Positives = 256/412 (62%), Gaps = 24/412 (5%)
Query: 65 TQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRL 124
T+IL+ LL GYDN+LRP +G R T ++TD++V S GPV +MEYTID+ F Q+W D RL
Sbjct: 43 TRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 125 KFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTI 184
KF M VL LN+ M KIW PDTFF N +KS AH +T PN+LLRI DG +LYT+RLT+
Sbjct: 103 KFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTV 162
Query: 185 NAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKP---SVEVADPKYWRLYQFAFV 241
AEC + L +FPMD H+CPL+F SY Y + E+ Y+W + SV VA+ RL Q+ +
Sbjct: 163 RAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-RLNQYDLL 221
Query: 242 GLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPA 301
G + I + +G+YV+MT F L R++GYF IQTY+PCI+TV+LS VSFW+N+++VPA
Sbjct: 222 GQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 281
Query: 302 RTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSN- 360
RT G+TTVLTMTTLS AR SLPKV+Y TAMD F++VC+ FVF+AL+E+ T++YFT
Sbjct: 282 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 341
Query: 361 --QKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGYQCLEGKDCASFFCC 418
GK+ ++ K K LI NN P Y G +
Sbjct: 342 YAWDGKSVVPEKPKKVK----------DPLIKKNNTYAPTATSYTPNLARGDPGLATIAK 391
Query: 419 FEDC-------RTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYL 463
T + ++KID SRI FP F +FNLVYW YL
Sbjct: 392 SATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYL 443
>gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 367 bits (942), Expect = e-101
Identities = 195/412 (47%), Positives = 256/412 (62%), Gaps = 24/412 (5%)
Query: 65 TQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRL 124
T+IL+ LL GYDN+LRP +G R T ++TD++V S GPV +MEYTID+ F Q+W D RL
Sbjct: 43 TRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 125 KFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTI 184
KF M VL LN+ M KIW PDTFF N +KS AH +T PN+LLRI DG +LYT+RLT+
Sbjct: 103 KFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTV 162
Query: 185 NAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKP---SVEVADPKYWRLYQFAFV 241
AEC + L +FPMD H+CPL+F SY Y + E+ Y+W + SV VA+ RL Q+ +
Sbjct: 163 RAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-RLNQYDLL 221
Query: 242 GLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPA 301
G + I + +G+YV+MT F L R++GYF IQTY+PCI+TV+LS VSFW+N+++VPA
Sbjct: 222 GQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 281
Query: 302 RTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSN- 360
RT G+TTVLTMTTLS AR SLPKV+Y TAMD F++VC+ FVF+AL+E+ T++YFT
Sbjct: 282 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 341
Query: 361 --QKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGYQCLEGKDCASFFCC 418
GK+ ++ K K LI NN P Y G +
Sbjct: 342 YAWDGKSVVPEKPKKVK----------DPLIKKNNTYAPTATSYTPNLARGDPGLATIAK 391
Query: 419 FEDC-------RTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYL 463
T + ++KID SRI FP F +FNLVYW YL
Sbjct: 392 SATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYL 443
>gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 367 bits (942), Expect = e-101
Identities = 195/412 (47%), Positives = 256/412 (62%), Gaps = 24/412 (5%)
Query: 65 TQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRL 124
T+IL+ LL GYDN+LRP +G R T ++TD++V S GPV +MEYTID+ F Q+W D RL
Sbjct: 43 TRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 125 KFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTI 184
KF M VL LN+ M KIW PDTFF N +KS AH +T PN+LLRI DG +LYT+RLT+
Sbjct: 103 KFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTV 162
Query: 185 NAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKP---SVEVADPKYWRLYQFAFV 241
AEC + L +FPMD H+CPL+F SY Y + E+ Y+W + SV VA+ RL Q+ +
Sbjct: 163 RAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-RLNQYDLL 221
Query: 242 GLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPA 301
G + I + +G+YV+MT F L R++GYF IQTY+PCI+TV+LS VSFW+N+++VPA
Sbjct: 222 GQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 281
Query: 302 RTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSN- 360
RT G+TTVLTMTTLS AR SLPKV+Y TAMD F++VC+ FVF+AL+E+ T++YFT
Sbjct: 282 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 341
Query: 361 --QKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGYQCLEGKDCASFFCC 418
GK+ ++ K K LI NN P Y G +
Sbjct: 342 YAWDGKSVVPEKPKKVK----------DPLIKKNNTYAPTATSYTPNLARGDPGLATIAK 391
Query: 419 FEDC-------RTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYL 463
T + ++KID SRI FP F +FNLVYW YL
Sbjct: 392 SATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYL 443
>gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 367 bits (942), Expect = e-101
Identities = 195/412 (47%), Positives = 256/412 (62%), Gaps = 24/412 (5%)
Query: 65 TQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRL 124
T+IL+ LL GYDN+LRP +G R T ++TD++V S GPV +MEYTID+ F Q+W D RL
Sbjct: 43 TRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 125 KFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTI 184
KF M VL LN+ M KIW PDTFF N +KS AH +T PN+LLRI DG +LYT+RLT+
Sbjct: 103 KFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTV 162
Query: 185 NAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKP---SVEVADPKYWRLYQFAFV 241
AEC + L +FPMD H+CPL+F SY Y + E+ Y+W + SV VA+ RL Q+ +
Sbjct: 163 RAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-RLNQYDLL 221
Query: 242 GLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPA 301
G + I + +G+YV+MT F L R++GYF IQTY+PCI+TV+LS VSFW+N+++VPA
Sbjct: 222 GQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 281
Query: 302 RTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSN- 360
RT G+TTVLTMTTLS AR SLPKV+Y TAMD F++VC+ FVF+AL+E+ T++YFT
Sbjct: 282 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 341
Query: 361 --QKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGYQCLEGKDCASFFCC 418
GK+ ++ K K LI NN P Y G +
Sbjct: 342 YAWDGKSVVPEKPKKVK----------DPLIKKNNTYAPTATSYTPNLARGDPGLATIAK 391
Query: 419 FEDC-------RTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYL 463
T + ++KID SRI FP F +FNLVYW YL
Sbjct: 392 SATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYL 443
>gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo
sapiens]
Length = 451
Score = 360 bits (925), Expect = 1e-99
Identities = 196/419 (46%), Positives = 257/419 (61%), Gaps = 40/419 (9%)
Query: 65 TQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRL 124
T+IL+ LL GYDN+LRP +G T + T++YV S GPV +MEYTID+ F Q W D RL
Sbjct: 43 TRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102
Query: 125 KFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTI 184
KF M +L LN+ M KIW PDTFF N +KS AH +T PN+LLRI +DG +LYT+RLT+
Sbjct: 103 KFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTV 162
Query: 185 NAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKW---KKPSVEVADPKYWRLYQFAFV 241
AEC + L +FPMD HSCPL+F SY Y +E+ Y W SV+VA P RL Q+ +
Sbjct: 163 QAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVA-PDGSRLNQYDLL 221
Query: 242 GLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPA 301
G E + +G+Y +MT F L R++GYF IQTY+PCI+TV+LS VSFW+N+++VPA
Sbjct: 222 GQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 281
Query: 302 RTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSN- 360
RT G+TTVLTMTTLS AR SLPKV+Y TAMD F++VC+ FVF+AL+E+ T++YFT
Sbjct: 282 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 341
Query: 361 --QKGKTATKDRKLKNKASM--------------TPGLHPGSTLIPMNNISVPQEDDYGY 404
GK+ D+K K KAS+ P L L ++ + E +
Sbjct: 342 WAWDGKSVVNDKK-KEKASVMIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPN--- 397
Query: 405 QCLEGKDCASFFCCFEDCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYL 463
+ E K + + ++KID SRI FP F FNLVYW YL
Sbjct: 398 KKPENKPAEA---------------KKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYL 441
>gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precursor
[Homo sapiens]
Length = 451
Score = 360 bits (925), Expect = 1e-99
Identities = 196/419 (46%), Positives = 257/419 (61%), Gaps = 40/419 (9%)
Query: 65 TQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRL 124
T+IL+ LL GYDN+LRP +G T + T++YV S GPV +MEYTID+ F Q W D RL
Sbjct: 43 TRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102
Query: 125 KFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTI 184
KF M +L LN+ M KIW PDTFF N +KS AH +T PN+LLRI +DG +LYT+RLT+
Sbjct: 103 KFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTV 162
Query: 185 NAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKW---KKPSVEVADPKYWRLYQFAFV 241
AEC + L +FPMD HSCPL+F SY Y +E+ Y W SV+VA P RL Q+ +
Sbjct: 163 QAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVA-PDGSRLNQYDLL 221
Query: 242 GLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPA 301
G E + +G+Y +MT F L R++GYF IQTY+PCI+TV+LS VSFW+N+++VPA
Sbjct: 222 GQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 281
Query: 302 RTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSN- 360
RT G+TTVLTMTTLS AR SLPKV+Y TAMD F++VC+ FVF+AL+E+ T++YFT
Sbjct: 282 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 341
Query: 361 --QKGKTATKDRKLKNKASM--------------TPGLHPGSTLIPMNNISVPQEDDYGY 404
GK+ D+K K KAS+ P L L ++ + E +
Sbjct: 342 WAWDGKSVVNDKK-KEKASVMIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPN--- 397
Query: 405 QCLEGKDCASFFCCFEDCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYL 463
+ E K + + ++KID SRI FP F FNLVYW YL
Sbjct: 398 KKPENKPAEA---------------KKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYL 441
>gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1
precursor [Homo sapiens]
Length = 474
Score = 283 bits (724), Expect = 2e-76
Identities = 158/438 (36%), Positives = 237/438 (54%), Gaps = 37/438 (8%)
Query: 64 ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSR 123
+ + ++ LL+GYD +LRPD G P + + V SI V +NM+YT+ + F Q+W D R
Sbjct: 37 VKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKR 96
Query: 124 LKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLT 183
L ++ L L++ + ++W+PDT+F N +KS H +T NR++R+ DG VLY LR+T
Sbjct: 97 LSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRIT 156
Query: 184 INAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGL 243
A C + L +P+DE +C LE SYGY ++IE+ W V L QF+ V
Sbjct: 157 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDY 216
Query: 244 RNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPART 303
+ ++ +G Y +++ F L R +GYF +QTY+P L +LSWVSFWIN DA AR
Sbjct: 217 KMVSKKVEFTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARV 276
Query: 304 SLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHY--FTSNQ 361
+LGITTVLTMTT+ST R++LPK+ YV A+D+++ CF+FVF AL+EY ++Y F
Sbjct: 277 ALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGKGP 336
Query: 362 KGKTATKDRKL---KNKASMTPGLHPGSTLIPMNNISVPQEDDYGYQCLEGKDCASFFCC 418
+ K A+K + KNK M I ++ + + E D +
Sbjct: 337 QKKGASKQDQSANEKNKLEMNKVQVDAHGNILLSTLEIRNETSGSEVLTSVSDPKATMYS 396
Query: 419 FEDC-------------------RTGSWREGRIHIR-------------IAKIDSYSRIF 446
++ R G +GRI R + ID +SR+F
Sbjct: 397 YDSASIQYRKPLSSREAYGRALDRHGVPSKGRIRRRASQLKVKIPDLTDVNSIDKWSRMF 456
Query: 447 FPTAFALFNLVYWVGYLY 464
FP F+LFN+VYW+ Y++
Sbjct: 457 FPITFSLFNVVYWLYYVH 474
>gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 2 [Homo sapiens]
Length = 474
Score = 281 bits (719), Expect = 9e-76
Identities = 155/439 (35%), Positives = 242/439 (55%), Gaps = 40/439 (9%)
Query: 64 ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSR 123
+ + ++ LL+GYD +LRPD G P + ++ + SI V +NM+YT+ + F Q W D R
Sbjct: 36 VKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKR 95
Query: 124 LKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLT 183
L +N L L++ + ++W+PDT+F N +KS H +T NR++R+ DG VLY LR+T
Sbjct: 96 LSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRIT 155
Query: 184 INAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGL 243
A C + L +P+DE +C LE SYGY ++IE+ W+ V L QF+ V
Sbjct: 156 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDY 215
Query: 244 RNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPART 303
+ T+ +G Y +++ F L R +GYF +QTY+P IL +LSWVSFWIN DA AR
Sbjct: 216 KLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARV 275
Query: 304 SLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYF------ 357
+LGITTVLTMTT++T R++LPK+ YV A+D+++ CF+FVF AL+EY ++Y
Sbjct: 276 ALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGP 335
Query: 358 ----TSNQKGKTATKDR-------------------KLKNKASMTPGL----HPGSTLIP 390
+ +K +A ++ ++KN+ + + + P ST++
Sbjct: 336 QRQKKAAEKAASANNEKMRLDVNKMDPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLA 395
Query: 391 MNNISVPQEDDYGYQCLEGKDCASFFCCFEDCRTGSWREGRIHIRIA------KIDSYSR 444
+ S+ + G++ + R R ++ I I ID +SR
Sbjct: 396 YDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRR-RASQLKITIPDLTDVNAIDRWSR 454
Query: 445 IFFPTAFALFNLVYWVGYL 463
IFFP F+ FN+VYW+ Y+
Sbjct: 455 IFFPVVFSFFNIVYWLYYV 473
>gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 2 precursor [Homo sapiens]
Length = 473
Score = 279 bits (713), Expect = 4e-75
Identities = 161/436 (36%), Positives = 237/436 (54%), Gaps = 36/436 (8%)
Query: 64 ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSR 123
+ + ++ LL+GYD +LRPD G P + ++ + SI V +NM+YT+ + F Q W D R
Sbjct: 37 VKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKR 96
Query: 124 LKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLT 183
L ++ L L++ + ++W+PDT+F N +KS H +T NR++R+ DG VLY LR+T
Sbjct: 97 LAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRIT 156
Query: 184 INAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGL 243
A C + L +P+DE +C LE SYGY ++IE+ W+ V + L QF+ V
Sbjct: 157 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEH 216
Query: 244 RNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPART 303
R + +G Y +++ F L R +GYF +QTY+P IL +LSWVSFWIN DA AR
Sbjct: 217 RLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARV 276
Query: 304 SLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYF----TS 359
+LGITTVLTMTT++T R++LPK+ YV A+D+++ CF+FVF AL+EY ++Y
Sbjct: 277 ALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGP 336
Query: 360 NQKGKTATKDRKLKNKASMTPGLH---PGSTLIPMNNISVPQEDDYGYQCLEGKDCASFF 416
++ K A K K KN S + G+ L+ + + G SF
Sbjct: 337 QRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFD 396
Query: 417 CCFEDCRTGSW-REG-------------RIHIR---------------IAKIDSYSRIFF 447
R S REG + H+R + ID +SRI F
Sbjct: 397 NSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVF 456
Query: 448 PTAFALFNLVYWVGYL 463
P F+LFNLVYW+ Y+
Sbjct: 457 PFTFSLFNLVYWLYYV 472
>gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 1 precursor [Homo sapiens]
Length = 473
Score = 279 bits (713), Expect = 4e-75
Identities = 161/436 (36%), Positives = 237/436 (54%), Gaps = 36/436 (8%)
Query: 64 ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSR 123
+ + ++ LL+GYD +LRPD G P + ++ + SI V +NM+YT+ + F Q W D R
Sbjct: 37 VKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKR 96
Query: 124 LKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLT 183
L ++ L L++ + ++W+PDT+F N +KS H +T NR++R+ DG VLY LR+T
Sbjct: 97 LAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRIT 156
Query: 184 INAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGL 243
A C + L +P+DE +C LE SYGY ++IE+ W+ V + L QF+ V
Sbjct: 157 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEH 216
Query: 244 RNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPART 303
R + +G Y +++ F L R +GYF +QTY+P IL +LSWVSFWIN DA AR
Sbjct: 217 RLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARV 276
Query: 304 SLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYF----TS 359
+LGITTVLTMTT++T R++LPK+ YV A+D+++ CF+FVF AL+EY ++Y
Sbjct: 277 ALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGP 336
Query: 360 NQKGKTATKDRKLKNKASMTPGLH---PGSTLIPMNNISVPQEDDYGYQCLEGKDCASFF 416
++ K A K K KN S + G+ L+ + + G SF
Sbjct: 337 QRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFD 396
Query: 417 CCFEDCRTGSW-REG-------------RIHIR---------------IAKIDSYSRIFF 447
R S REG + H+R + ID +SRI F
Sbjct: 397 NSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVF 456
Query: 448 PTAFALFNLVYWVGYL 463
P F+LFNLVYW+ Y+
Sbjct: 457 PFTFSLFNLVYWLYYV 472
>gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 1 [Homo sapiens]
Length = 512
Score = 270 bits (689), Expect = 3e-72
Identities = 131/314 (41%), Positives = 196/314 (62%), Gaps = 3/314 (0%)
Query: 64 ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSR 123
+ + ++ LL+GYD +LRPD G P + ++ + SI V +NM+YT+ + F Q W D R
Sbjct: 36 VKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKR 95
Query: 124 LKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLT 183
L +N L L++ + ++W+PDT+F N +KS H +T NR++R+ DG VLY LR+T
Sbjct: 96 LSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRIT 155
Query: 184 INAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGL 243
A C + L +P+DE +C LE SYGY ++IE+ W+ V L QF+ V
Sbjct: 156 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDY 215
Query: 244 RNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPART 303
+ T+ +G Y +++ F L R +GYF +QTY+P IL +LSWVSFWIN DA AR
Sbjct: 216 KLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARV 275
Query: 304 SLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNQKG 363
+LGITTVLTMTT++T R++LPK+ YV A+D+++ CF+FVF AL+EY ++Y G
Sbjct: 276 ALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFF---G 332
Query: 364 KTATKDRKLKNKAS 377
+ + +K KA+
Sbjct: 333 RGPQRQKKAAEKAA 346
Score = 40.0 bits (92), Expect = 0.004
Identities = 15/25 (60%), Positives = 20/25 (80%)
Query: 439 IDSYSRIFFPTAFALFNLVYWVGYL 463
ID +SRIFFP F+ FN+VYW+ Y+
Sbjct: 487 IDRWSRIFFPVVFSFFNIVYWLYYV 511
>gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta
precursor [Homo sapiens]
Length = 452
Score = 266 bits (680), Expect = 3e-71
Identities = 153/410 (37%), Positives = 227/410 (55%), Gaps = 18/410 (4%)
Query: 68 LNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRLKFN 127
L+ L+ GY RP IG P + + V SI + NMEYT+ + Q+W DSRL +N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 128 STMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTINAE 187
T + L L+S V K+W+PDTF N++ + H +T N+L+R+ DG +LY++R+T
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 188 CYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGLRNST 247
C + L +PMDE C L+ SYGY +I Y W + + +L QF R +T
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYRFTT 223
Query: 248 EITHTIS-GDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLG 306
E+ + S G + +++ F L R G + IQ+Y+P +L V +SWVSFWI++ AVPAR SLG
Sbjct: 224 ELMNFKSAGQFPRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLG 283
Query: 307 ITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNQKGKTA 366
ITTVLTMTTL AR SLP+ S + A+D++ +C++FVFAAL+EY H F ++ + K
Sbjct: 284 ITTVLTMTTLMVSARSSLPRASAIKALDVYFWICYVFVFAALVEYAFAH-FNADYRKKQK 342
Query: 367 TKDRKLKNKASMTPGLHPGSTLIPMNNISVPQE--DDYGYQCLEGKDCASFFC----CFE 420
K + + +A M + L ++ V QE + + G S+ E
Sbjct: 343 AKVKVSRPRAEM--DVRNAIVLFSLSAAGVTQELAISRRQRRVPGNLMGSYRSVGVETGE 400
Query: 421 DCRTGSWR---EGRIHIRIAKIDS-----YSRIFFPTAFALFNLVYWVGY 462
+ G+ R +G I R+ ID+ Y+R FP AFA N++YW Y
Sbjct: 401 TKKEGAARSGGQGGIRARLRPIDADTIDIYARAVFPAAFAAVNVIYWAAY 450
>gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 457
Score = 265 bits (678), Expect = 5e-71
Identities = 160/420 (38%), Positives = 231/420 (55%), Gaps = 18/420 (4%)
Query: 56 APK-IHEGDITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDII 114
APK + D L GYD ++RP+ P + ++++NS G + M+Y ++I
Sbjct: 32 APKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIF 91
Query: 115 FAQTWFDSRLKFNSTMK-VLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWND 173
Q W D RL +N L L+ +M+ IW PD FF N + + H ITT N+LLRI +
Sbjct: 92 LRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRN 151
Query: 174 GRVLYTLRLTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKP-SVEVADPKY 232
G VLY++R+T+ C + L NFPMD +C ++ S+GY N++ ++W++ +V+VAD
Sbjct: 152 GNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGL- 210
Query: 233 WRLYQFAFVGLRNSTEIT-HTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVS 291
L QF ++ T H +G + + F L R+MGY+ IQ YIP +L V+LSW+S
Sbjct: 211 -TLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWIS 269
Query: 292 FWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEY 351
FWIN DA PAR LGITTVLTMTT S+ +R SLPKVSYV A+D++++VC +FVF+AL+EY
Sbjct: 270 FWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEY 329
Query: 352 GTLHYFTSNQKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGYQCLEGKD 411
+++ + K + ++ +K+ M N S G CL+ KD
Sbjct: 330 AAVNFVSRQHKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSA---YGMGPACLQAKD 386
Query: 412 CASFFCCFEDCRTG-------SWREGR--IHIRIAKIDSYSRIFFPTAFALFNLVYWVGY 462
S T S E R R KID SRI FP AF +FN+ YW+ Y
Sbjct: 387 GISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 446
>gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 263 bits (673), Expect = 2e-70
Identities = 155/418 (37%), Positives = 232/418 (55%), Gaps = 40/418 (9%)
Query: 63 DITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDS 122
D L GYD ++RP+ P + ++++NS G V M+Y ++I Q W DS
Sbjct: 46 DFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDS 105
Query: 123 RLKFNSTMK-VLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLR 181
RL ++ L L+ +M+ IW PD FF N + ++ H +TT N+LLRI +G+VLY++R
Sbjct: 106 RLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIR 165
Query: 182 LTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPS-VEVADPKYWRLYQFAF 240
LT+ C + L NFPMD +C ++ S+GY N++ ++W V+VA+ L QF
Sbjct: 166 LTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGL--TLPQFI- 222
Query: 241 VGLRNSTEI----THTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINK 296
L+ E+ H +G + + + F L R+MGY+ IQ YIP +L V+LSWVSFWIN
Sbjct: 223 --LKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINM 280
Query: 297 DAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHY 356
DA PAR +LGITTVLTMTT S+ +R SLPKVSYV A+D++++VC +FVFAAL+EY +++
Sbjct: 281 DAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNF 340
Query: 357 FTSNQKGKTATKDR-KLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGY------QCLEG 409
+ K + R K +NK V +E + + CL+
Sbjct: 341 VSRQHKEFLRLRRRQKRQNKEE-----------------DVTRESRFNFSGYGMGHCLQV 383
Query: 410 KDCASFFC-----CFEDCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGY 462
KD + + + G + + R +ID+ SR FP AF +FN+ YW+ Y
Sbjct: 384 KDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 263 bits (673), Expect = 2e-70
Identities = 155/418 (37%), Positives = 232/418 (55%), Gaps = 40/418 (9%)
Query: 63 DITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDS 122
D L GYD ++RP+ P + ++++NS G V M+Y ++I Q W DS
Sbjct: 46 DFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDS 105
Query: 123 RLKFNSTMK-VLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLR 181
RL ++ L L+ +M+ IW PD FF N + ++ H +TT N+LLRI +G+VLY++R
Sbjct: 106 RLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIR 165
Query: 182 LTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPS-VEVADPKYWRLYQFAF 240
LT+ C + L NFPMD +C ++ S+GY N++ ++W V+VA+ L QF
Sbjct: 166 LTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGL--TLPQFI- 222
Query: 241 VGLRNSTEI----THTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINK 296
L+ E+ H +G + + + F L R+MGY+ IQ YIP +L V+LSWVSFWIN
Sbjct: 223 --LKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINM 280
Query: 297 DAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHY 356
DA PAR +LGITTVLTMTT S+ +R SLPKVSYV A+D++++VC +FVFAAL+EY +++
Sbjct: 281 DAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNF 340
Query: 357 FTSNQKGKTATKDR-KLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGY------QCLEG 409
+ K + R K +NK V +E + + CL+
Sbjct: 341 VSRQHKEFLRLRRRQKRQNKEE-----------------DVTRESRFNFSGYGMGHCLQV 383
Query: 410 KDCASFFC-----CFEDCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGY 462
KD + + + G + + R +ID+ SR FP AF +FN+ YW+ Y
Sbjct: 384 KDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens]
Length = 449
Score = 263 bits (672), Expect = 3e-70
Identities = 159/423 (37%), Positives = 228/423 (53%), Gaps = 48/423 (11%)
Query: 63 DITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDS 122
D L GYD ++RP+ P + ++++NS G + M+Y ++I Q W D
Sbjct: 45 DFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDP 104
Query: 123 RLKFNSTMK-VLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLR 181
RL ++ L L+ +M+ IW PD FF N + ++ H +TT N+LLRI+ +G VLY++R
Sbjct: 105 RLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIR 164
Query: 182 LTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPS-VEVADPKYWRLYQFAF 240
LT+ C + L NFPMD +C ++ S+GY N++ ++W+ + V+VA+ L QF
Sbjct: 165 LTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGL--TLPQFLL 222
Query: 241 VGLRNSTEIT-HTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAV 299
++ T H +G + + + F L R+MGY+ IQ YIP +L V+LSWVSFWIN DA
Sbjct: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282
Query: 300 PARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTS 359
PAR +LGITTVLTMTT S+ +R SLPKVSYV A+D++++VC +FVF+AL+EY ++ F S
Sbjct: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVN-FVS 341
Query: 360 NQKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGYQCLEGKDCASFFCCF 419
Q + RK KNK T M CL+ KD
Sbjct: 342 RQHKELLRFRRKRKNKDDEVRESRFSFTAYGMG------------PCLQAKD-------- 381
Query: 420 EDCRTGSWREGRIH-----------------IRIAKIDSYSRIFFPTAFALFNLVYWVGY 462
G +G H R KID+ SR FP AF +FN+ YWV Y
Sbjct: 382 -----GMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 436
Query: 463 LYL 465
L
Sbjct: 437 KIL 439
>gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens]
Length = 452
Score = 263 bits (671), Expect = 3e-70
Identities = 154/418 (36%), Positives = 232/418 (55%), Gaps = 40/418 (9%)
Query: 63 DITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDS 122
D L GYD ++RP+ P + ++++NS G + M+Y ++I Q W DS
Sbjct: 46 DFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDS 105
Query: 123 RLKFNSTMK-VLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLR 181
RL ++ L L+ +M+ IW PD FF N + ++ H +TT N+LLRI +G+VLY++R
Sbjct: 106 RLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIR 165
Query: 182 LTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPS-VEVADPKYWRLYQFAF 240
LT+ C + L NFPMD +C ++ S+GY N++ ++W V+VA+ L QF
Sbjct: 166 LTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGL--TLPQFI- 222
Query: 241 VGLRNSTEI----THTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINK 296
L+ E+ H +G + + + F L R+MGY+ IQ YIP +L V+LSWVSFWIN
Sbjct: 223 --LKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINM 280
Query: 297 DAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHY 356
DA PAR +LGITTVLTMTT S+ +R SLPKVSYV A+D++++VC +FVFAAL+EY +++
Sbjct: 281 DAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNF 340
Query: 357 FTSNQKGKTATKDR-KLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGY------QCLEG 409
+ K + R K +NK V +E + + CL+
Sbjct: 341 VSRQHKEFLRLRRRQKRQNKEE-----------------DVTRESRFNFSGYGMGHCLQV 383
Query: 410 KDCASFFC-----CFEDCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGY 462
KD + + + G + + R +ID+ SR FP AF +FN+ YW+ Y
Sbjct: 384 KDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.139 0.441
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,206,076
Number of Sequences: 37866
Number of extensions: 734827
Number of successful extensions: 2210
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2041
Number of HSP's gapped (non-prelim): 104
length of query: 465
length of database: 18,247,518
effective HSP length: 106
effective length of query: 359
effective length of database: 14,233,722
effective search space: 5109906198
effective search space used: 5109906198
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.