Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 31563534

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31563534 replication factor C 2 isoform 1 [Homo sapiens]
         (354 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31563534 replication factor C 2 isoform 1 [Homo sapiens]           705   0.0  
gi|28882049 replication factor C 2 isoform 2 [Homo sapiens]           622   e-178
gi|6677723 replication factor C 5 isoform 1 [Homo sapiens]            218   5e-57
gi|194306571 replication factor C 5 isoform 2 [Homo sapiens]          209   2e-54
gi|194306567 replication factor C 5 isoform 2 [Homo sapiens]          209   2e-54
gi|31881687 replication factor C 4 [Homo sapiens]                     199   4e-51
gi|4506491 replication factor C 4 [Homo sapiens]                      199   4e-51
gi|194306569 replication factor C 5 isoform 3 [Homo sapiens]          160   2e-39
gi|108773789 replication factor C 3 isoform 2 [Homo sapiens]          103   3e-22
gi|4506489 replication factor C 3 isoform 1 [Homo sapiens]            103   3e-22
gi|32528306 replication factor C large subunit [Homo sapiens]          60   3e-09
gi|18426902 Werner helicase interacting protein isoform 1 [Homo ...    55   1e-07
gi|18426904 Werner helicase interacting protein isoform 2 [Homo ...    45   1e-04
gi|27501458 CTF18, chromosome transmission fidelity factor 18 ho...    44   3e-04
gi|19718796 RAD17 homolog isoform 1 [Homo sapiens]                     42   6e-04
gi|19718794 RAD17 homolog isoform 1 [Homo sapiens]                     42   6e-04
gi|19718792 RAD17 homolog isoform 1 [Homo sapiens]                     42   6e-04
gi|19718784 RAD17 homolog isoform 1 [Homo sapiens]                     42   6e-04
gi|4506383 RAD17 homolog isoform 1 [Homo sapiens]                      42   6e-04
gi|19718786 RAD17 homolog isoform 2 [Homo sapiens]                     42   6e-04
gi|4502703 cell division cycle 6 protein [Homo sapiens]                37   0.021
gi|22749187 putative adenylate kinase-like protein C9orf98 [Homo...    35   0.078
gi|7242140 ClpX caseinolytic protease X homolog [Homo sapiens]         35   0.078
gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]                  35   0.078
gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]                  35   0.078
gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens]      35   0.13 
gi|31742536 fidgetin-like 1 [Homo sapiens]                             35   0.13 
gi|112789543 fidgetin-like 1 [Homo sapiens]                            35   0.13 
gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]                       34   0.17 
gi|7657689 YME1-like 1 isoform 3 [Homo sapiens]                        34   0.17 

>gi|31563534 replication factor C 2 isoform 1 [Homo sapiens]
          Length = 354

 Score =  705 bits (1820), Expect = 0.0
 Identities = 354/354 (100%), Positives = 354/354 (100%)

Query: 1   MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL 60
           MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL
Sbjct: 1   MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL 60

Query: 61  EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKI 120
           EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKI
Sbjct: 61  EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKI 120

Query: 121 KMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP 180
           KMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP
Sbjct: 121 KMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP 180

Query: 181 IQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTF 240
           IQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTF
Sbjct: 181 IQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTF 240

Query: 241 SGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIF 300
           SGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIF
Sbjct: 241 SGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIF 300

Query: 301 RVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS 354
           RVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS
Sbjct: 301 RVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS 354


>gi|28882049 replication factor C 2 isoform 2 [Homo sapiens]
          Length = 320

 Score =  622 bits (1605), Expect = e-178
 Identities = 320/354 (90%), Positives = 320/354 (90%), Gaps = 34/354 (9%)

Query: 1   MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL 60
           MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL
Sbjct: 1   MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL 60

Query: 61  EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKI 120
           EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASND          
Sbjct: 61  EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASND---------- 110

Query: 121 KMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP 180
                                   SMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP
Sbjct: 111 ------------------------SMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP 146

Query: 181 IQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTF 240
           IQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTF
Sbjct: 147 IQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTF 206

Query: 241 SGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIF 300
           SGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIF
Sbjct: 207 SGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIF 266

Query: 301 RVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS 354
           RVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS
Sbjct: 267 RVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS 320


>gi|6677723 replication factor C 5 isoform 1 [Homo sapiens]
          Length = 340

 Score =  218 bits (556), Expect = 5e-57
 Identities = 118/317 (37%), Positives = 187/317 (58%), Gaps = 3/317 (0%)

Query: 28  PGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSIL 87
           P +     LPWVEKYRP  LN+++ ++D +S ++ F  E  +P++++ GPPGTGKT++IL
Sbjct: 12  PAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTIL 71

Query: 88  CLARALLGPALKDAM-LELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSM 146
             A+ L       +M LELNAS+DRGID++R  I  FA  +    KG  K++ILDEAD+M
Sbjct: 72  ACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKG-FKLVILDEADAM 130

Query: 147 TDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVI 206
           T  AQ ALRR +E +++ TRF L CN   KII  +QSRC   R+  LT   ++ RL +V+
Sbjct: 131 TQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVV 190

Query: 207 EKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEM 266
           E+E+V  ++DG++A++  + GDMR+ALN LQST   FG +  E V+     P    +  +
Sbjct: 191 EEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANI 250

Query: 267 IQHCVNANIDEAYKILAHLWHL-GYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHM 325
           +   +N +   AY+ +  L  L G +  DI+  I            +++  + ++     
Sbjct: 251 LDWMLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEY 310

Query: 326 KIAEGVNSLLQMAGLLA 342
           +++ G N  +Q++ L+A
Sbjct: 311 RLSVGTNEKIQLSSLIA 327


>gi|194306571 replication factor C 5 isoform 2 [Homo sapiens]
          Length = 319

 Score =  209 bits (533), Expect = 2e-54
 Identities = 114/306 (37%), Positives = 182/306 (59%), Gaps = 3/306 (0%)

Query: 39  VEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPAL 98
           VEKYRP  LN+++ ++D +S ++ F  E  +P++++ GPPGTGKT++IL  A+ L     
Sbjct: 2   VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKE 61

Query: 99  KDAM-LELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRT 157
             +M LELNAS+DRGID++R  I  FA  +    KG  K++ILDEAD+MT  AQ ALRR 
Sbjct: 62  FGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKG-FKLVILDEADAMTQDAQNALRRV 120

Query: 158 MEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDG 217
           +E +++ TRF L CN   KII  +QSRC   R+  LT   ++ RL +V+E+E+V  ++DG
Sbjct: 121 IEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDG 180

Query: 218 LEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDE 277
           ++A++  + GDMR+ALN LQST   FG +  E V+     P    +  ++   +N +   
Sbjct: 181 MKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTT 240

Query: 278 AYKILAHLWHL-GYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQ 336
           AY+ +  L  L G +  DI+  I            +++  + ++     +++ G N  +Q
Sbjct: 241 AYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQ 300

Query: 337 MAGLLA 342
           ++ L+A
Sbjct: 301 LSSLIA 306


>gi|194306567 replication factor C 5 isoform 2 [Homo sapiens]
          Length = 319

 Score =  209 bits (533), Expect = 2e-54
 Identities = 114/306 (37%), Positives = 182/306 (59%), Gaps = 3/306 (0%)

Query: 39  VEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPAL 98
           VEKYRP  LN+++ ++D +S ++ F  E  +P++++ GPPGTGKT++IL  A+ L     
Sbjct: 2   VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKE 61

Query: 99  KDAM-LELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRT 157
             +M LELNAS+DRGID++R  I  FA  +    KG  K++ILDEAD+MT  AQ ALRR 
Sbjct: 62  FGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKG-FKLVILDEADAMTQDAQNALRRV 120

Query: 158 MEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDG 217
           +E +++ TRF L CN   KII  +QSRC   R+  LT   ++ RL +V+E+E+V  ++DG
Sbjct: 121 IEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDG 180

Query: 218 LEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDE 277
           ++A++  + GDMR+ALN LQST   FG +  E V+     P    +  ++   +N +   
Sbjct: 181 MKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTT 240

Query: 278 AYKILAHLWHL-GYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQ 336
           AY+ +  L  L G +  DI+  I            +++  + ++     +++ G N  +Q
Sbjct: 241 AYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQ 300

Query: 337 MAGLLA 342
           ++ L+A
Sbjct: 301 LSSLIA 306


>gi|31881687 replication factor C 4 [Homo sapiens]
          Length = 363

 Score =  199 bits (505), Expect = 4e-51
 Identities = 124/334 (37%), Positives = 190/334 (56%), Gaps = 17/334 (5%)

Query: 29  GSAGHYE----LPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTT 84
           GS+G  +    +PWVEKYRP  ++E+   E+ V+ L+      ++PN++  GPPGTGKT+
Sbjct: 27  GSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTS 86

Query: 85  SILCLARALLGPAL-KDAMLELNASNDRGIDVVRNKIKMFAQQKVT------LPKGRHKI 137
           +IL  AR L GP L +  +LELNAS++RGI VVR K+K FAQ  V+       P    KI
Sbjct: 87  TILAAARELFGPELFRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKI 146

Query: 138 IILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQ 197
           +ILDEADSMT  AQ ALRRTME  SKTTRF L CN   +IIEP+ SRC+  R+  L+D  
Sbjct: 147 VILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKI 206

Query: 198 ILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDE 257
              RL+++ +KE V  +D+G+  ++  ++GD+R+A+  LQS     G    E   KV  +
Sbjct: 207 QQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTG--GKEITEKVITD 264

Query: 258 PHPLLVKEMIQ----HCVNANIDEAYKILAHLWHLGYSPEDIIGNIFRVCKTFQMAEYLK 313
              ++  E I      C + + D+   ++  L   G++   ++  +  V     +++  K
Sbjct: 265 IAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQLHDVVVENNLSDKQK 324

Query: 314 LEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQK 347
               +++      +A+G +  LQ+  L A + Q+
Sbjct: 325 SIITEKLAEVDKCLADGADEHLQLISLCATVMQQ 358


>gi|4506491 replication factor C 4 [Homo sapiens]
          Length = 363

 Score =  199 bits (505), Expect = 4e-51
 Identities = 124/334 (37%), Positives = 190/334 (56%), Gaps = 17/334 (5%)

Query: 29  GSAGHYE----LPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTT 84
           GS+G  +    +PWVEKYRP  ++E+   E+ V+ L+      ++PN++  GPPGTGKT+
Sbjct: 27  GSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTS 86

Query: 85  SILCLARALLGPAL-KDAMLELNASNDRGIDVVRNKIKMFAQQKVT------LPKGRHKI 137
           +IL  AR L GP L +  +LELNAS++RGI VVR K+K FAQ  V+       P    KI
Sbjct: 87  TILAAARELFGPELFRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKI 146

Query: 138 IILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQ 197
           +ILDEADSMT  AQ ALRRTME  SKTTRF L CN   +IIEP+ SRC+  R+  L+D  
Sbjct: 147 VILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKI 206

Query: 198 ILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDE 257
              RL+++ +KE V  +D+G+  ++  ++GD+R+A+  LQS     G    E   KV  +
Sbjct: 207 QQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTG--GKEITEKVITD 264

Query: 258 PHPLLVKEMIQ----HCVNANIDEAYKILAHLWHLGYSPEDIIGNIFRVCKTFQMAEYLK 313
              ++  E I      C + + D+   ++  L   G++   ++  +  V     +++  K
Sbjct: 265 IAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQLHDVVVENNLSDKQK 324

Query: 314 LEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQK 347
               +++      +A+G +  LQ+  L A + Q+
Sbjct: 325 SIITEKLAEVDKCLADGADEHLQLISLCATVMQQ 358


>gi|194306569 replication factor C 5 isoform 3 [Homo sapiens]
          Length = 255

 Score =  160 bits (404), Expect = 2e-39
 Identities = 88/242 (36%), Positives = 140/242 (57%), Gaps = 2/242 (0%)

Query: 102 MLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIY 161
           +LELNAS+DRGID++R  I  FA  +    KG  K++ILDEAD+MT  AQ ALRR +E +
Sbjct: 2   VLELNASDDRGIDIIRGPILSFASTRTIFKKG-FKLVILDEADAMTQDAQNALRRVIEKF 60

Query: 162 SKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAI 221
           ++ TRF L CN   KII  +QSRC   R+  LT   ++ RL +V+E+E+V  ++DG++A+
Sbjct: 61  TENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKAL 120

Query: 222 IFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKI 281
           +  + GDMR+ALN LQST   FG +  E V+     P    +  ++   +N +   AY+ 
Sbjct: 121 VTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTAYRN 180

Query: 282 LAHLWHL-GYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGL 340
           +  L  L G +  DI+  I            +++  + ++     +++ G N  +Q++ L
Sbjct: 181 ITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQLSSL 240

Query: 341 LA 342
           +A
Sbjct: 241 IA 242


>gi|108773789 replication factor C 3 isoform 2 [Homo sapiens]
          Length = 305

 Score =  103 bits (256), Expect = 3e-22
 Identities = 65/200 (32%), Positives = 99/200 (49%), Gaps = 28/200 (14%)

Query: 38  WVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPA 97
           WV+KYRP  L  +  +++  ++L    + G+ P++++ GP G GK T I+C+ R L G  
Sbjct: 4   WVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVG 63

Query: 98  LKDAM------------------------LELNASNDRGID--VVRNKIKMFAQ--QKVT 129
           ++                           LE+N S+    D  V++  +K  AQ  Q  T
Sbjct: 64  VEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLET 123

Query: 130 LPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLR 189
             +   K+++L E D +T  AQ ALRRTME Y  T R  L CN++ K+I PI+SRC  +R
Sbjct: 124 NSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVR 183

Query: 190 YTKLTDAQILTRLMNVIEKE 209
               +   I   L  V +KE
Sbjct: 184 VPAPSIEDICHVLSTVCKKE 203


>gi|4506489 replication factor C 3 isoform 1 [Homo sapiens]
          Length = 356

 Score =  103 bits (256), Expect = 3e-22
 Identities = 65/200 (32%), Positives = 99/200 (49%), Gaps = 28/200 (14%)

Query: 38  WVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPA 97
           WV+KYRP  L  +  +++  ++L    + G+ P++++ GP G GK T I+C+ R L G  
Sbjct: 4   WVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVG 63

Query: 98  LKDAM------------------------LELNASNDRGID--VVRNKIKMFAQ--QKVT 129
           ++                           LE+N S+    D  V++  +K  AQ  Q  T
Sbjct: 64  VEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLET 123

Query: 130 LPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLR 189
             +   K+++L E D +T  AQ ALRRTME Y  T R  L CN++ K+I PI+SRC  +R
Sbjct: 124 NSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVR 183

Query: 190 YTKLTDAQILTRLMNVIEKE 209
               +   I   L  V +KE
Sbjct: 184 VPAPSIEDICHVLSTVCKKE 203


>gi|32528306 replication factor C large subunit [Homo sapiens]
          Length = 1147

 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 58/239 (24%), Positives = 93/239 (38%), Gaps = 43/239 (17%)

Query: 36  LPWVEKYRPVKLNEIVGNEDTVSRLEVFAR--------------------------EGNV 69
           L WV+KY+P  L  I+G +   S      R                            + 
Sbjct: 584 LLWVDKYKPTSLKTIIGQQGDQSCANKLLRWLRNWQKSSSEDKKHAKFGKFSGKDDGSSF 643

Query: 70  PNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVR---------NKI 120
              +++GPPG GKTT+      +L+   L  + +ELNAS+ R    ++           I
Sbjct: 644 KAALLSGPPGVGKTTTA-----SLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSI 698

Query: 121 KMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP 180
           K F              +I+DE D M     +   + +    K T+  + C  +D+    
Sbjct: 699 KGFYSNGAASSVSTKHALIMDEVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPK 758

Query: 181 IQSR---CAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNL 236
           I+S    C  LR+ +    QI   +M++  KE +      +  II  A  D+RQ L+NL
Sbjct: 759 IRSLVHYCFDLRFQRPRVEQIKGAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNL 817


>gi|18426902 Werner helicase interacting protein isoform 1 [Homo
           sapiens]
          Length = 665

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 64/269 (23%), Positives = 101/269 (37%), Gaps = 49/269 (18%)

Query: 11  GEVEAQDSDPAPAFSKAPGSAGHYEL-------------PWVEKYRPVKLNEIVGNEDTV 57
           G  +A  ++ A AF  + G   H                P  +  RP  L +  G    V
Sbjct: 187 GHWDADAAEAATAFGASGGGRPHPRALAAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAV 246

Query: 58  SR---LEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAM--LELNASNDRG 112
            +   L        +P++I+ GPPG GKTT    LA  +   + K ++  + L+A+N + 
Sbjct: 247 GQDTLLRSLLETNEIPSLILWGPPGCGKTT----LAHIIASNSKKHSIRFVTLSATNAKT 302

Query: 113 IDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACN 172
            D VR+ IK    +K      R  I+ +DE        Q      +E  + T   A   N
Sbjct: 303 ND-VRDVIKQAQNEKSFFK--RKTILFIDEIHRFNKSQQDTFLPHVECGTITLIGATTEN 359

Query: 173 ASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDD---------------- 216
            S ++   + SRC V+   KL    ++T LM  I    +   D                 
Sbjct: 360 PSFQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLDSSRPTDPLSHSSNSSSE 419

Query: 217 --------GLEAIIFTAQGDMRQALNNLQ 237
                    ++ + + + GD R  LN LQ
Sbjct: 420 PAMFIEDKAVDTLAYLSDGDARAGLNGLQ 448


>gi|18426904 Werner helicase interacting protein isoform 2 [Homo
           sapiens]
          Length = 640

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 62/269 (23%), Positives = 97/269 (36%), Gaps = 74/269 (27%)

Query: 11  GEVEAQDSDPAPAFSKAPGSAGHYEL-------------PWVEKYRPVKLNEIVGNEDTV 57
           G  +A  ++ A AF  + G   H                P  +  RP  L +  G    V
Sbjct: 187 GHWDADAAEAATAFGASGGGRPHPRALAAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAV 246

Query: 58  SR---LEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAM--LELNASNDRG 112
            +   L        +P++I+ GPPG GKTT    LA  +   + K ++  + L+A+N + 
Sbjct: 247 GQDTLLRSLLETNEIPSLILWGPPGCGKTT----LAHIIASNSKKHSIRFVTLSATNAKT 302

Query: 113 IDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACN 172
            D VR+ IK    +K      R  I+ +DE                       RF    N
Sbjct: 303 ND-VRDVIKQAQNEKSFFK--RKTILFIDEIH---------------------RF----N 334

Query: 173 ASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDD---------------- 216
            S ++   + SRC V+   KL    ++T LM  I    +   D                 
Sbjct: 335 KSQQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLDSSRPTDPLSHSSNSSSE 394

Query: 217 --------GLEAIIFTAQGDMRQALNNLQ 237
                    ++ + + + GD R  LN LQ
Sbjct: 395 PAMFIEDKAVDTLAYLSDGDARAGLNGLQ 423


>gi|27501458 CTF18, chromosome transmission fidelity factor 18
           homolog [Homo sapiens]
          Length = 975

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 42/196 (21%), Positives = 78/196 (39%), Gaps = 32/196 (16%)

Query: 73  IIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKIKMFAQQKVTL-P 131
           ++ GPPG GKTT    +AR         +++E+NAS+DR  +V R +I+   Q +  L  
Sbjct: 371 LLCGPPGLGKTTLAHVIARHA-----GYSVVEMNASDDRSPEVFRTRIEAATQMESVLGA 425

Query: 132 KGRHKIIILDEADSMTDGAQQAL-----------------------RRTMEIYSKTTRFA 168
            G+   +++DE D     A   L                        R            
Sbjct: 426 GGKPNCLVIDEIDGAPVAAINVLLSILNRKGPQEVGPQGPAVPSGGGRRRRAEGGLLMRP 485

Query: 169 LACNASDKI---IEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTA 225
           + C  +D+    +  ++ +  +L +     ++++ RL  V  ++ +      L A+    
Sbjct: 486 IICICNDQFAPSLRQLKQQAFLLHFPPTLPSRLVQRLQEVSLRQGMRADPGVLAALCEKT 545

Query: 226 QGDMRQALNNLQSTFS 241
             D+R  +N LQ  +S
Sbjct: 546 DNDIRACINTLQFLYS 561


>gi|19718796 RAD17 homolog isoform 1 [Homo sapiens]
          Length = 670

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 50/256 (19%), Positives = 102/256 (39%), Gaps = 51/256 (19%)

Query: 37  PWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN--------IIIAGPPGTGKTTSILC 88
           PWV+KY+P   +E+  ++  +  +E + +   +          ++I GPPG GKTT++  
Sbjct: 79  PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKI 138

Query: 89  LAR-------ALLGPALKDAMLE-----LNASNDRGIDVVRNKIKMFAQQKVTLPKGR-- 134
           L++         + P L D   +      N  +   +   +++I +F +  +   K    
Sbjct: 139 LSKEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKL 198

Query: 135 ----------HKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKII------ 178
                      KII++++  +        L   +  Y +  R  L    SD +       
Sbjct: 199 QMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFIISDSLSGDNNQR 258

Query: 179 ----EPIQSRCAV--LRYTKLTDAQILTRLMNVIEKE------RVPYTD-DGLEAIIFTA 225
               + IQ  C++  + +  +    ++  L  ++  E      ++   D   LE +    
Sbjct: 259 LLFPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGC 318

Query: 226 QGDMRQALNNLQSTFS 241
            GD+R A+N+LQ + S
Sbjct: 319 SGDIRSAINSLQFSSS 334


>gi|19718794 RAD17 homolog isoform 1 [Homo sapiens]
          Length = 670

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 50/256 (19%), Positives = 102/256 (39%), Gaps = 51/256 (19%)

Query: 37  PWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN--------IIIAGPPGTGKTTSILC 88
           PWV+KY+P   +E+  ++  +  +E + +   +          ++I GPPG GKTT++  
Sbjct: 79  PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKI 138

Query: 89  LAR-------ALLGPALKDAMLE-----LNASNDRGIDVVRNKIKMFAQQKVTLPKGR-- 134
           L++         + P L D   +      N  +   +   +++I +F +  +   K    
Sbjct: 139 LSKEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKL 198

Query: 135 ----------HKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKII------ 178
                      KII++++  +        L   +  Y +  R  L    SD +       
Sbjct: 199 QMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFIISDSLSGDNNQR 258

Query: 179 ----EPIQSRCAV--LRYTKLTDAQILTRLMNVIEKE------RVPYTD-DGLEAIIFTA 225
               + IQ  C++  + +  +    ++  L  ++  E      ++   D   LE +    
Sbjct: 259 LLFPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGC 318

Query: 226 QGDMRQALNNLQSTFS 241
            GD+R A+N+LQ + S
Sbjct: 319 SGDIRSAINSLQFSSS 334


>gi|19718792 RAD17 homolog isoform 1 [Homo sapiens]
          Length = 670

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 50/256 (19%), Positives = 102/256 (39%), Gaps = 51/256 (19%)

Query: 37  PWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN--------IIIAGPPGTGKTTSILC 88
           PWV+KY+P   +E+  ++  +  +E + +   +          ++I GPPG GKTT++  
Sbjct: 79  PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKI 138

Query: 89  LAR-------ALLGPALKDAMLE-----LNASNDRGIDVVRNKIKMFAQQKVTLPKGR-- 134
           L++         + P L D   +      N  +   +   +++I +F +  +   K    
Sbjct: 139 LSKEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKL 198

Query: 135 ----------HKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKII------ 178
                      KII++++  +        L   +  Y +  R  L    SD +       
Sbjct: 199 QMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFIISDSLSGDNNQR 258

Query: 179 ----EPIQSRCAV--LRYTKLTDAQILTRLMNVIEKE------RVPYTD-DGLEAIIFTA 225
               + IQ  C++  + +  +    ++  L  ++  E      ++   D   LE +    
Sbjct: 259 LLFPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGC 318

Query: 226 QGDMRQALNNLQSTFS 241
            GD+R A+N+LQ + S
Sbjct: 319 SGDIRSAINSLQFSSS 334


>gi|19718784 RAD17 homolog isoform 1 [Homo sapiens]
          Length = 670

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 50/256 (19%), Positives = 102/256 (39%), Gaps = 51/256 (19%)

Query: 37  PWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN--------IIIAGPPGTGKTTSILC 88
           PWV+KY+P   +E+  ++  +  +E + +   +          ++I GPPG GKTT++  
Sbjct: 79  PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKI 138

Query: 89  LAR-------ALLGPALKDAMLE-----LNASNDRGIDVVRNKIKMFAQQKVTLPKGR-- 134
           L++         + P L D   +      N  +   +   +++I +F +  +   K    
Sbjct: 139 LSKEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKL 198

Query: 135 ----------HKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKII------ 178
                      KII++++  +        L   +  Y +  R  L    SD +       
Sbjct: 199 QMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFIISDSLSGDNNQR 258

Query: 179 ----EPIQSRCAV--LRYTKLTDAQILTRLMNVIEKE------RVPYTD-DGLEAIIFTA 225
               + IQ  C++  + +  +    ++  L  ++  E      ++   D   LE +    
Sbjct: 259 LLFPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGC 318

Query: 226 QGDMRQALNNLQSTFS 241
            GD+R A+N+LQ + S
Sbjct: 319 SGDIRSAINSLQFSSS 334


>gi|4506383 RAD17 homolog isoform 1 [Homo sapiens]
          Length = 670

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 50/256 (19%), Positives = 102/256 (39%), Gaps = 51/256 (19%)

Query: 37  PWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN--------IIIAGPPGTGKTTSILC 88
           PWV+KY+P   +E+  ++  +  +E + +   +          ++I GPPG GKTT++  
Sbjct: 79  PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKI 138

Query: 89  LAR-------ALLGPALKDAMLE-----LNASNDRGIDVVRNKIKMFAQQKVTLPKGR-- 134
           L++         + P L D   +      N  +   +   +++I +F +  +   K    
Sbjct: 139 LSKEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKL 198

Query: 135 ----------HKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKII------ 178
                      KII++++  +        L   +  Y +  R  L    SD +       
Sbjct: 199 QMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFIISDSLSGDNNQR 258

Query: 179 ----EPIQSRCAV--LRYTKLTDAQILTRLMNVIEKE------RVPYTD-DGLEAIIFTA 225
               + IQ  C++  + +  +    ++  L  ++  E      ++   D   LE +    
Sbjct: 259 LLFPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGC 318

Query: 226 QGDMRQALNNLQSTFS 241
            GD+R A+N+LQ + S
Sbjct: 319 SGDIRSAINSLQFSSS 334


>gi|19718786 RAD17 homolog isoform 2 [Homo sapiens]
          Length = 681

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 50/256 (19%), Positives = 102/256 (39%), Gaps = 51/256 (19%)

Query: 37  PWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN--------IIIAGPPGTGKTTSILC 88
           PWV+KY+P   +E+  ++  +  +E + +   +          ++I GPPG GKTT++  
Sbjct: 90  PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKI 149

Query: 89  LAR-------ALLGPALKDAMLE-----LNASNDRGIDVVRNKIKMFAQQKVTLPKGR-- 134
           L++         + P L D   +      N  +   +   +++I +F +  +   K    
Sbjct: 150 LSKEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKL 209

Query: 135 ----------HKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKII------ 178
                      KII++++  +        L   +  Y +  R  L    SD +       
Sbjct: 210 QMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFIISDSLSGDNNQR 269

Query: 179 ----EPIQSRCAV--LRYTKLTDAQILTRLMNVIEKE------RVPYTD-DGLEAIIFTA 225
               + IQ  C++  + +  +    ++  L  ++  E      ++   D   LE +    
Sbjct: 270 LLFPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGC 329

Query: 226 QGDMRQALNNLQSTFS 241
            GD+R A+N+LQ + S
Sbjct: 330 SGDIRSAINSLQFSSS 345


>gi|4502703 cell division cycle 6 protein [Homo sapiens]
          Length = 560

 Score = 37.4 bits (85), Expect = 0.021
 Identities = 50/208 (24%), Positives = 89/208 (42%), Gaps = 56/208 (26%)

Query: 71  NIIIAGPPGTGKTTSILCLARAL-------------------------LGPALKDAMLEL 105
           ++ ++G PGTGKT    CL+R L                         + PA+   + + 
Sbjct: 197 SLYLSGAPGTGKTA---CLSRILQDLKKELKGFKTIMLNCMSLRTAQAVFPAIAQEICQE 253

Query: 106 NASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTME------ 159
             S   G D++R       ++ +T  KG   +++LDE D +    Q  L    E      
Sbjct: 254 EVSRPAGKDMMRK-----LEKHMTAEKGPMIVLVLDEMDQLDSKGQDVLYTLFEWPWLSN 308

Query: 160 IYSKTTRFALACNASDKIIEPIQSR--C--AVLRYTKLTDAQILTRL---MNVIEKERVP 212
            +      A   + +D+I+  +Q+R  C   +L +   T  QI+T L   +N + +++V 
Sbjct: 309 SHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLNQVSRDQV- 367

Query: 213 YTDDGLEAIIFTAQ------GDMRQALN 234
             D+   A+ F A+      GD+R+AL+
Sbjct: 368 -LDNA--AVQFCARKVSAVSGDVRKALD 392


>gi|22749187 putative adenylate kinase-like protein C9orf98 [Homo
           sapiens]
          Length = 479

 Score = 35.4 bits (80), Expect = 0.078
 Identities = 36/123 (29%), Positives = 55/123 (44%), Gaps = 19/123 (15%)

Query: 68  NVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKIKMFAQQK 127
           NVP I+I GPP +GKTT  + L + L    L    L LN  +    +  R    ++ Q+K
Sbjct: 56  NVPRIVILGPPASGKTTIAMWLCKHLNSSLLTLENLILNEFSYTATEARR----LYLQRK 111

Query: 128 VTLPKGRHKIII---LDEADSMTDG---------AQQALRRTMEIYSKTTRFALACNASD 175
            T+P      +I   L E D +  G          +QALR  ++    T R  +  +A D
Sbjct: 112 -TVPSALLVQLIQERLAEEDCIKQGWILDGIPETREQALR--IQTLGITPRHVIVLSAPD 168

Query: 176 KII 178
            ++
Sbjct: 169 TVL 171


>gi|7242140 ClpX caseinolytic protease X homolog [Homo sapiens]
          Length = 633

 Score = 35.4 bits (80), Expect = 0.078
 Identities = 27/102 (26%), Positives = 41/102 (40%), Gaps = 13/102 (12%)

Query: 71  NIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKIKMFAQQKVTL 130
           NI++ GP G+GKT     LA+ L  P        L  +   G D+     K+       +
Sbjct: 288 NILLLGPTGSGKTLLAQTLAKCLDVPFAICDCTTLTQAGYVGEDIESVIAKLLQDANYNV 347

Query: 131 PKGRHKIIILDEADSM-------------TDGAQQALRRTME 159
            K +  I+ LDE D +              +G QQ L + +E
Sbjct: 348 EKAQQGIVFLDEVDKIGSVPGIHQLRDVGGEGVQQGLLKLLE 389


>gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]
          Length = 750

 Score = 35.4 bits (80), Expect = 0.078
 Identities = 35/115 (30%), Positives = 53/115 (46%), Gaps = 18/115 (15%)

Query: 45  VKLNEIVGNEDTVSRL----------EVFAREGNVP--NIIIAGPPGTGKTTSILCLARA 92
           VK  ++ GN+ T+  +          EV+   G VP   +++ GPPG GKT     +A  
Sbjct: 156 VKFEDVGGNDMTLKEVCKMLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIAGE 215

Query: 93  LLGPALKDAMLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMT 147
           L  P LK A  E+  S   G      K++   +Q V+       II +DE D++T
Sbjct: 216 LDLPILKVAAPEI-VSGVSGES--EQKLRELFEQAVS---NAPCIIFIDEIDAIT 264


>gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]
          Length = 856

 Score = 35.4 bits (80), Expect = 0.078
 Identities = 35/115 (30%), Positives = 53/115 (46%), Gaps = 18/115 (15%)

Query: 45  VKLNEIVGNEDTVSRL----------EVFAREGNVP--NIIIAGPPGTGKTTSILCLARA 92
           VK  ++ GN+ T+  +          EV+   G VP   +++ GPPG GKT     +A  
Sbjct: 262 VKFEDVGGNDMTLKEVCKMLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIAGE 321

Query: 93  LLGPALKDAMLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMT 147
           L  P LK A  E+  S   G      K++   +Q V+       II +DE D++T
Sbjct: 322 LDLPILKVAAPEI-VSGVSGES--EQKLRELFEQAVS---NAPCIIFIDEIDAIT 370


>gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens]
          Length = 1844

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 28/135 (20%), Positives = 53/135 (39%), Gaps = 45/135 (33%)

Query: 31   AGHYELPWVEKYRPVKLNEIVGNEDTVSRLEVFARE------------------------ 66
            +G  ++ W EKY+P   +E++GNE  + +L  + ++                        
Sbjct: 1047 SGTEDMLWTEKYQPQTASELIGNELAIKKLHSWLKDWKRRAELEERQNLKGKRDEKHEDF 1106

Query: 67   -GNVP---------------NIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASND 110
             G +                 ++I GP G GKT ++   A+      L   + E+NAS+ 
Sbjct: 1107 SGGIDFKGSSDDEEESRLCNTVLITGPTGVGKTAAVYACAQ-----ELGFKIFEVNASSQ 1161

Query: 111  RGIDVVRNKIKMFAQ 125
            R    + +++K   Q
Sbjct: 1162 RSGRQILSQLKEATQ 1176


>gi|31742536 fidgetin-like 1 [Homo sapiens]
          Length = 674

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 43/173 (24%), Positives = 73/173 (42%), Gaps = 24/173 (13%)

Query: 67  GNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNAS-NDRGIDVVRNKIKMFAQ 125
           G    I++ GPPGTGKT    C+A          +   L +     G  +VR    +FA 
Sbjct: 432 GPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVR---ALFAV 488

Query: 126 QKVTLPKGRHKIIILDEADSMT----DGAQQALRR-----TMEIYSKTTR------FALA 170
            +   P     +I +DE DS+     DG  ++ RR      +++   TT          A
Sbjct: 489 ARCQQP----AVIFIDEIDSLLSQRGDGEHESSRRIKTEFLVQLDGATTSSEDRILVVGA 544

Query: 171 CNASDKIIEPIQSRCAVLRYTKLTDAQILTRL-MNVIEKERVPYTDDGLEAII 222
            N   +I E  + R     Y  L +A    ++ +N++ KE+   +++ +E I+
Sbjct: 545 TNRPQEIDEAARRRLVKRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIV 597


>gi|112789543 fidgetin-like 1 [Homo sapiens]
          Length = 674

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 43/173 (24%), Positives = 73/173 (42%), Gaps = 24/173 (13%)

Query: 67  GNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNAS-NDRGIDVVRNKIKMFAQ 125
           G    I++ GPPGTGKT    C+A          +   L +     G  +VR    +FA 
Sbjct: 432 GPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVR---ALFAV 488

Query: 126 QKVTLPKGRHKIIILDEADSMT----DGAQQALRR-----TMEIYSKTTR------FALA 170
            +   P     +I +DE DS+     DG  ++ RR      +++   TT          A
Sbjct: 489 ARCQQP----AVIFIDEIDSLLSQRGDGEHESSRRIKTEFLVQLDGATTSSEDRILVVGA 544

Query: 171 CNASDKIIEPIQSRCAVLRYTKLTDAQILTRL-MNVIEKERVPYTDDGLEAII 222
            N   +I E  + R     Y  L +A    ++ +N++ KE+   +++ +E I+
Sbjct: 545 TNRPQEIDEAARRRLVKRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIV 597


>gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]
          Length = 773

 Score = 34.3 bits (77), Expect = 0.17
 Identities = 33/105 (31%), Positives = 47/105 (44%), Gaps = 20/105 (19%)

Query: 67  GNVPN-IIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDR-----GIDVVRNKI 120
           G +P  I++ GPPGTGKT     LARA+ G A         +  D      G   +RN  
Sbjct: 369 GKLPKGILLVGPPGTGKT----LLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRN-- 422

Query: 121 KMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTT 165
            +F + K   P     +I +DE DS+     + +   M  YS+ T
Sbjct: 423 -LFREAKANAP----CVIFIDELDSV---GGKRIESPMHPYSRQT 459


>gi|7657689 YME1-like 1 isoform 3 [Homo sapiens]
          Length = 716

 Score = 34.3 bits (77), Expect = 0.17
 Identities = 33/105 (31%), Positives = 47/105 (44%), Gaps = 20/105 (19%)

Query: 67  GNVPN-IIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDR-----GIDVVRNKI 120
           G +P  I++ GPPGTGKT     LARA+ G A         +  D      G   +RN  
Sbjct: 312 GKLPKGILLVGPPGTGKT----LLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRN-- 365

Query: 121 KMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTT 165
            +F + K   P     +I +DE DS+     + +   M  YS+ T
Sbjct: 366 -LFREAKANAP----CVIFIDELDSV---GGKRIESPMHPYSRQT 402


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,941,397
Number of Sequences: 37866
Number of extensions: 546697
Number of successful extensions: 1699
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 1622
Number of HSP's gapped (non-prelim): 101
length of query: 354
length of database: 18,247,518
effective HSP length: 103
effective length of query: 251
effective length of database: 14,347,320
effective search space: 3601177320
effective search space used: 3601177320
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press