BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|31563534 replication factor C 2 isoform 1 [Homo sapiens] (354 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|31563534 replication factor C 2 isoform 1 [Homo sapiens] 705 0.0 gi|28882049 replication factor C 2 isoform 2 [Homo sapiens] 622 e-178 gi|6677723 replication factor C 5 isoform 1 [Homo sapiens] 218 5e-57 gi|194306571 replication factor C 5 isoform 2 [Homo sapiens] 209 2e-54 gi|194306567 replication factor C 5 isoform 2 [Homo sapiens] 209 2e-54 gi|31881687 replication factor C 4 [Homo sapiens] 199 4e-51 gi|4506491 replication factor C 4 [Homo sapiens] 199 4e-51 gi|194306569 replication factor C 5 isoform 3 [Homo sapiens] 160 2e-39 gi|108773789 replication factor C 3 isoform 2 [Homo sapiens] 103 3e-22 gi|4506489 replication factor C 3 isoform 1 [Homo sapiens] 103 3e-22 gi|32528306 replication factor C large subunit [Homo sapiens] 60 3e-09 gi|18426902 Werner helicase interacting protein isoform 1 [Homo ... 55 1e-07 gi|18426904 Werner helicase interacting protein isoform 2 [Homo ... 45 1e-04 gi|27501458 CTF18, chromosome transmission fidelity factor 18 ho... 44 3e-04 gi|19718796 RAD17 homolog isoform 1 [Homo sapiens] 42 6e-04 gi|19718794 RAD17 homolog isoform 1 [Homo sapiens] 42 6e-04 gi|19718792 RAD17 homolog isoform 1 [Homo sapiens] 42 6e-04 gi|19718784 RAD17 homolog isoform 1 [Homo sapiens] 42 6e-04 gi|4506383 RAD17 homolog isoform 1 [Homo sapiens] 42 6e-04 gi|19718786 RAD17 homolog isoform 2 [Homo sapiens] 42 6e-04 gi|4502703 cell division cycle 6 protein [Homo sapiens] 37 0.021 gi|22749187 putative adenylate kinase-like protein C9orf98 [Homo... 35 0.078 gi|7242140 ClpX caseinolytic protease X homolog [Homo sapiens] 35 0.078 gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens] 35 0.078 gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens] 35 0.078 gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens] 35 0.13 gi|31742536 fidgetin-like 1 [Homo sapiens] 35 0.13 gi|112789543 fidgetin-like 1 [Homo sapiens] 35 0.13 gi|21327685 YME1-like 1 isoform 1 [Homo sapiens] 34 0.17 gi|7657689 YME1-like 1 isoform 3 [Homo sapiens] 34 0.17 >gi|31563534 replication factor C 2 isoform 1 [Homo sapiens] Length = 354 Score = 705 bits (1820), Expect = 0.0 Identities = 354/354 (100%), Positives = 354/354 (100%) Query: 1 MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL 60 MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL Sbjct: 1 MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL 60 Query: 61 EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKI 120 EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKI Sbjct: 61 EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKI 120 Query: 121 KMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP 180 KMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP Sbjct: 121 KMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP 180 Query: 181 IQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTF 240 IQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTF Sbjct: 181 IQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTF 240 Query: 241 SGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIF 300 SGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIF Sbjct: 241 SGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIF 300 Query: 301 RVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS 354 RVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS Sbjct: 301 RVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS 354 >gi|28882049 replication factor C 2 isoform 2 [Homo sapiens] Length = 320 Score = 622 bits (1605), Expect = e-178 Identities = 320/354 (90%), Positives = 320/354 (90%), Gaps = 34/354 (9%) Query: 1 MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL 60 MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL Sbjct: 1 MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL 60 Query: 61 EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKI 120 EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASND Sbjct: 61 EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASND---------- 110 Query: 121 KMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP 180 SMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP Sbjct: 111 ------------------------SMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP 146 Query: 181 IQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTF 240 IQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTF Sbjct: 147 IQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTF 206 Query: 241 SGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIF 300 SGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIF Sbjct: 207 SGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIF 266 Query: 301 RVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS 354 RVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS Sbjct: 267 RVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS 320 >gi|6677723 replication factor C 5 isoform 1 [Homo sapiens] Length = 340 Score = 218 bits (556), Expect = 5e-57 Identities = 118/317 (37%), Positives = 187/317 (58%), Gaps = 3/317 (0%) Query: 28 PGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSIL 87 P + LPWVEKYRP LN+++ ++D +S ++ F E +P++++ GPPGTGKT++IL Sbjct: 12 PAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTIL 71 Query: 88 CLARALLGPALKDAM-LELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSM 146 A+ L +M LELNAS+DRGID++R I FA + KG K++ILDEAD+M Sbjct: 72 ACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKG-FKLVILDEADAM 130 Query: 147 TDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVI 206 T AQ ALRR +E +++ TRF L CN KII +QSRC R+ LT ++ RL +V+ Sbjct: 131 TQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVV 190 Query: 207 EKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEM 266 E+E+V ++DG++A++ + GDMR+ALN LQST FG + E V+ P + + Sbjct: 191 EEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANI 250 Query: 267 IQHCVNANIDEAYKILAHLWHL-GYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHM 325 + +N + AY+ + L L G + DI+ I +++ + ++ Sbjct: 251 LDWMLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEY 310 Query: 326 KIAEGVNSLLQMAGLLA 342 +++ G N +Q++ L+A Sbjct: 311 RLSVGTNEKIQLSSLIA 327 >gi|194306571 replication factor C 5 isoform 2 [Homo sapiens] Length = 319 Score = 209 bits (533), Expect = 2e-54 Identities = 114/306 (37%), Positives = 182/306 (59%), Gaps = 3/306 (0%) Query: 39 VEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPAL 98 VEKYRP LN+++ ++D +S ++ F E +P++++ GPPGTGKT++IL A+ L Sbjct: 2 VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKE 61 Query: 99 KDAM-LELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRT 157 +M LELNAS+DRGID++R I FA + KG K++ILDEAD+MT AQ ALRR Sbjct: 62 FGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKG-FKLVILDEADAMTQDAQNALRRV 120 Query: 158 MEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDG 217 +E +++ TRF L CN KII +QSRC R+ LT ++ RL +V+E+E+V ++DG Sbjct: 121 IEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDG 180 Query: 218 LEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDE 277 ++A++ + GDMR+ALN LQST FG + E V+ P + ++ +N + Sbjct: 181 MKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTT 240 Query: 278 AYKILAHLWHL-GYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQ 336 AY+ + L L G + DI+ I +++ + ++ +++ G N +Q Sbjct: 241 AYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQ 300 Query: 337 MAGLLA 342 ++ L+A Sbjct: 301 LSSLIA 306 >gi|194306567 replication factor C 5 isoform 2 [Homo sapiens] Length = 319 Score = 209 bits (533), Expect = 2e-54 Identities = 114/306 (37%), Positives = 182/306 (59%), Gaps = 3/306 (0%) Query: 39 VEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPAL 98 VEKYRP LN+++ ++D +S ++ F E +P++++ GPPGTGKT++IL A+ L Sbjct: 2 VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKE 61 Query: 99 KDAM-LELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRT 157 +M LELNAS+DRGID++R I FA + KG K++ILDEAD+MT AQ ALRR Sbjct: 62 FGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKG-FKLVILDEADAMTQDAQNALRRV 120 Query: 158 MEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDG 217 +E +++ TRF L CN KII +QSRC R+ LT ++ RL +V+E+E+V ++DG Sbjct: 121 IEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDG 180 Query: 218 LEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDE 277 ++A++ + GDMR+ALN LQST FG + E V+ P + ++ +N + Sbjct: 181 MKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTT 240 Query: 278 AYKILAHLWHL-GYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQ 336 AY+ + L L G + DI+ I +++ + ++ +++ G N +Q Sbjct: 241 AYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQ 300 Query: 337 MAGLLA 342 ++ L+A Sbjct: 301 LSSLIA 306 >gi|31881687 replication factor C 4 [Homo sapiens] Length = 363 Score = 199 bits (505), Expect = 4e-51 Identities = 124/334 (37%), Positives = 190/334 (56%), Gaps = 17/334 (5%) Query: 29 GSAGHYE----LPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTT 84 GS+G + +PWVEKYRP ++E+ E+ V+ L+ ++PN++ GPPGTGKT+ Sbjct: 27 GSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTS 86 Query: 85 SILCLARALLGPAL-KDAMLELNASNDRGIDVVRNKIKMFAQQKVT------LPKGRHKI 137 +IL AR L GP L + +LELNAS++RGI VVR K+K FAQ V+ P KI Sbjct: 87 TILAAARELFGPELFRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKI 146 Query: 138 IILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQ 197 +ILDEADSMT AQ ALRRTME SKTTRF L CN +IIEP+ SRC+ R+ L+D Sbjct: 147 VILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKI 206 Query: 198 ILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDE 257 RL+++ +KE V +D+G+ ++ ++GD+R+A+ LQS G E KV + Sbjct: 207 QQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTG--GKEITEKVITD 264 Query: 258 PHPLLVKEMIQ----HCVNANIDEAYKILAHLWHLGYSPEDIIGNIFRVCKTFQMAEYLK 313 ++ E I C + + D+ ++ L G++ ++ + V +++ K Sbjct: 265 IAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQLHDVVVENNLSDKQK 324 Query: 314 LEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQK 347 +++ +A+G + LQ+ L A + Q+ Sbjct: 325 SIITEKLAEVDKCLADGADEHLQLISLCATVMQQ 358 >gi|4506491 replication factor C 4 [Homo sapiens] Length = 363 Score = 199 bits (505), Expect = 4e-51 Identities = 124/334 (37%), Positives = 190/334 (56%), Gaps = 17/334 (5%) Query: 29 GSAGHYE----LPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTT 84 GS+G + +PWVEKYRP ++E+ E+ V+ L+ ++PN++ GPPGTGKT+ Sbjct: 27 GSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTS 86 Query: 85 SILCLARALLGPAL-KDAMLELNASNDRGIDVVRNKIKMFAQQKVT------LPKGRHKI 137 +IL AR L GP L + +LELNAS++RGI VVR K+K FAQ V+ P KI Sbjct: 87 TILAAARELFGPELFRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKI 146 Query: 138 IILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQ 197 +ILDEADSMT AQ ALRRTME SKTTRF L CN +IIEP+ SRC+ R+ L+D Sbjct: 147 VILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKI 206 Query: 198 ILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDE 257 RL+++ +KE V +D+G+ ++ ++GD+R+A+ LQS G E KV + Sbjct: 207 QQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTG--GKEITEKVITD 264 Query: 258 PHPLLVKEMIQ----HCVNANIDEAYKILAHLWHLGYSPEDIIGNIFRVCKTFQMAEYLK 313 ++ E I C + + D+ ++ L G++ ++ + V +++ K Sbjct: 265 IAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQLHDVVVENNLSDKQK 324 Query: 314 LEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQK 347 +++ +A+G + LQ+ L A + Q+ Sbjct: 325 SIITEKLAEVDKCLADGADEHLQLISLCATVMQQ 358 >gi|194306569 replication factor C 5 isoform 3 [Homo sapiens] Length = 255 Score = 160 bits (404), Expect = 2e-39 Identities = 88/242 (36%), Positives = 140/242 (57%), Gaps = 2/242 (0%) Query: 102 MLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIY 161 +LELNAS+DRGID++R I FA + KG K++ILDEAD+MT AQ ALRR +E + Sbjct: 2 VLELNASDDRGIDIIRGPILSFASTRTIFKKG-FKLVILDEADAMTQDAQNALRRVIEKF 60 Query: 162 SKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAI 221 ++ TRF L CN KII +QSRC R+ LT ++ RL +V+E+E+V ++DG++A+ Sbjct: 61 TENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKAL 120 Query: 222 IFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKI 281 + + GDMR+ALN LQST FG + E V+ P + ++ +N + AY+ Sbjct: 121 VTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTAYRN 180 Query: 282 LAHLWHL-GYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGL 340 + L L G + DI+ I +++ + ++ +++ G N +Q++ L Sbjct: 181 ITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQLSSL 240 Query: 341 LA 342 +A Sbjct: 241 IA 242 >gi|108773789 replication factor C 3 isoform 2 [Homo sapiens] Length = 305 Score = 103 bits (256), Expect = 3e-22 Identities = 65/200 (32%), Positives = 99/200 (49%), Gaps = 28/200 (14%) Query: 38 WVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPA 97 WV+KYRP L + +++ ++L + G+ P++++ GP G GK T I+C+ R L G Sbjct: 4 WVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVG 63 Query: 98 LKDAM------------------------LELNASNDRGID--VVRNKIKMFAQ--QKVT 129 ++ LE+N S+ D V++ +K AQ Q T Sbjct: 64 VEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLET 123 Query: 130 LPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLR 189 + K+++L E D +T AQ ALRRTME Y T R L CN++ K+I PI+SRC +R Sbjct: 124 NSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVR 183 Query: 190 YTKLTDAQILTRLMNVIEKE 209 + I L V +KE Sbjct: 184 VPAPSIEDICHVLSTVCKKE 203 >gi|4506489 replication factor C 3 isoform 1 [Homo sapiens] Length = 356 Score = 103 bits (256), Expect = 3e-22 Identities = 65/200 (32%), Positives = 99/200 (49%), Gaps = 28/200 (14%) Query: 38 WVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPA 97 WV+KYRP L + +++ ++L + G+ P++++ GP G GK T I+C+ R L G Sbjct: 4 WVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVG 63 Query: 98 LKDAM------------------------LELNASNDRGID--VVRNKIKMFAQ--QKVT 129 ++ LE+N S+ D V++ +K AQ Q T Sbjct: 64 VEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLET 123 Query: 130 LPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLR 189 + K+++L E D +T AQ ALRRTME Y T R L CN++ K+I PI+SRC +R Sbjct: 124 NSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVR 183 Query: 190 YTKLTDAQILTRLMNVIEKE 209 + I L V +KE Sbjct: 184 VPAPSIEDICHVLSTVCKKE 203 >gi|32528306 replication factor C large subunit [Homo sapiens] Length = 1147 Score = 60.1 bits (144), Expect = 3e-09 Identities = 58/239 (24%), Positives = 93/239 (38%), Gaps = 43/239 (17%) Query: 36 LPWVEKYRPVKLNEIVGNEDTVSRLEVFAR--------------------------EGNV 69 L WV+KY+P L I+G + S R + Sbjct: 584 LLWVDKYKPTSLKTIIGQQGDQSCANKLLRWLRNWQKSSSEDKKHAKFGKFSGKDDGSSF 643 Query: 70 PNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVR---------NKI 120 +++GPPG GKTT+ +L+ L + +ELNAS+ R ++ I Sbjct: 644 KAALLSGPPGVGKTTTA-----SLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSI 698 Query: 121 KMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP 180 K F +I+DE D M + + + K T+ + C +D+ Sbjct: 699 KGFYSNGAASSVSTKHALIMDEVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPK 758 Query: 181 IQSR---CAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNL 236 I+S C LR+ + QI +M++ KE + + II A D+RQ L+NL Sbjct: 759 IRSLVHYCFDLRFQRPRVEQIKGAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNL 817 >gi|18426902 Werner helicase interacting protein isoform 1 [Homo sapiens] Length = 665 Score = 55.1 bits (131), Expect = 1e-07 Identities = 64/269 (23%), Positives = 101/269 (37%), Gaps = 49/269 (18%) Query: 11 GEVEAQDSDPAPAFSKAPGSAGHYEL-------------PWVEKYRPVKLNEIVGNEDTV 57 G +A ++ A AF + G H P + RP L + G V Sbjct: 187 GHWDADAAEAATAFGASGGGRPHPRALAAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAV 246 Query: 58 SR---LEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAM--LELNASNDRG 112 + L +P++I+ GPPG GKTT LA + + K ++ + L+A+N + Sbjct: 247 GQDTLLRSLLETNEIPSLILWGPPGCGKTT----LAHIIASNSKKHSIRFVTLSATNAKT 302 Query: 113 IDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACN 172 D VR+ IK +K R I+ +DE Q +E + T A N Sbjct: 303 ND-VRDVIKQAQNEKSFFK--RKTILFIDEIHRFNKSQQDTFLPHVECGTITLIGATTEN 359 Query: 173 ASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDD---------------- 216 S ++ + SRC V+ KL ++T LM I + D Sbjct: 360 PSFQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLDSSRPTDPLSHSSNSSSE 419 Query: 217 --------GLEAIIFTAQGDMRQALNNLQ 237 ++ + + + GD R LN LQ Sbjct: 420 PAMFIEDKAVDTLAYLSDGDARAGLNGLQ 448 >gi|18426904 Werner helicase interacting protein isoform 2 [Homo sapiens] Length = 640 Score = 45.1 bits (105), Expect = 1e-04 Identities = 62/269 (23%), Positives = 97/269 (36%), Gaps = 74/269 (27%) Query: 11 GEVEAQDSDPAPAFSKAPGSAGHYEL-------------PWVEKYRPVKLNEIVGNEDTV 57 G +A ++ A AF + G H P + RP L + G V Sbjct: 187 GHWDADAAEAATAFGASGGGRPHPRALAAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAV 246 Query: 58 SR---LEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAM--LELNASNDRG 112 + L +P++I+ GPPG GKTT LA + + K ++ + L+A+N + Sbjct: 247 GQDTLLRSLLETNEIPSLILWGPPGCGKTT----LAHIIASNSKKHSIRFVTLSATNAKT 302 Query: 113 IDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACN 172 D VR+ IK +K R I+ +DE RF N Sbjct: 303 ND-VRDVIKQAQNEKSFFK--RKTILFIDEIH---------------------RF----N 334 Query: 173 ASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDD---------------- 216 S ++ + SRC V+ KL ++T LM I + D Sbjct: 335 KSQQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLDSSRPTDPLSHSSNSSSE 394 Query: 217 --------GLEAIIFTAQGDMRQALNNLQ 237 ++ + + + GD R LN LQ Sbjct: 395 PAMFIEDKAVDTLAYLSDGDARAGLNGLQ 423 >gi|27501458 CTF18, chromosome transmission fidelity factor 18 homolog [Homo sapiens] Length = 975 Score = 43.5 bits (101), Expect = 3e-04 Identities = 42/196 (21%), Positives = 78/196 (39%), Gaps = 32/196 (16%) Query: 73 IIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKIKMFAQQKVTL-P 131 ++ GPPG GKTT +AR +++E+NAS+DR +V R +I+ Q + L Sbjct: 371 LLCGPPGLGKTTLAHVIARHA-----GYSVVEMNASDDRSPEVFRTRIEAATQMESVLGA 425 Query: 132 KGRHKIIILDEADSMTDGAQQAL-----------------------RRTMEIYSKTTRFA 168 G+ +++DE D A L R Sbjct: 426 GGKPNCLVIDEIDGAPVAAINVLLSILNRKGPQEVGPQGPAVPSGGGRRRRAEGGLLMRP 485 Query: 169 LACNASDKI---IEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTA 225 + C +D+ + ++ + +L + ++++ RL V ++ + L A+ Sbjct: 486 IICICNDQFAPSLRQLKQQAFLLHFPPTLPSRLVQRLQEVSLRQGMRADPGVLAALCEKT 545 Query: 226 QGDMRQALNNLQSTFS 241 D+R +N LQ +S Sbjct: 546 DNDIRACINTLQFLYS 561 >gi|19718796 RAD17 homolog isoform 1 [Homo sapiens] Length = 670 Score = 42.4 bits (98), Expect = 6e-04 Identities = 50/256 (19%), Positives = 102/256 (39%), Gaps = 51/256 (19%) Query: 37 PWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN--------IIIAGPPGTGKTTSILC 88 PWV+KY+P +E+ ++ + +E + + + ++I GPPG GKTT++ Sbjct: 79 PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKI 138 Query: 89 LAR-------ALLGPALKDAMLE-----LNASNDRGIDVVRNKIKMFAQQKVTLPKGR-- 134 L++ + P L D + N + + +++I +F + + K Sbjct: 139 LSKEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKL 198 Query: 135 ----------HKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKII------ 178 KII++++ + L + Y + R L SD + Sbjct: 199 QMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFIISDSLSGDNNQR 258 Query: 179 ----EPIQSRCAV--LRYTKLTDAQILTRLMNVIEKE------RVPYTD-DGLEAIIFTA 225 + IQ C++ + + + ++ L ++ E ++ D LE + Sbjct: 259 LLFPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGC 318 Query: 226 QGDMRQALNNLQSTFS 241 GD+R A+N+LQ + S Sbjct: 319 SGDIRSAINSLQFSSS 334 >gi|19718794 RAD17 homolog isoform 1 [Homo sapiens] Length = 670 Score = 42.4 bits (98), Expect = 6e-04 Identities = 50/256 (19%), Positives = 102/256 (39%), Gaps = 51/256 (19%) Query: 37 PWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN--------IIIAGPPGTGKTTSILC 88 PWV+KY+P +E+ ++ + +E + + + ++I GPPG GKTT++ Sbjct: 79 PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKI 138 Query: 89 LAR-------ALLGPALKDAMLE-----LNASNDRGIDVVRNKIKMFAQQKVTLPKGR-- 134 L++ + P L D + N + + +++I +F + + K Sbjct: 139 LSKEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKL 198 Query: 135 ----------HKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKII------ 178 KII++++ + L + Y + R L SD + Sbjct: 199 QMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFIISDSLSGDNNQR 258 Query: 179 ----EPIQSRCAV--LRYTKLTDAQILTRLMNVIEKE------RVPYTD-DGLEAIIFTA 225 + IQ C++ + + + ++ L ++ E ++ D LE + Sbjct: 259 LLFPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGC 318 Query: 226 QGDMRQALNNLQSTFS 241 GD+R A+N+LQ + S Sbjct: 319 SGDIRSAINSLQFSSS 334 >gi|19718792 RAD17 homolog isoform 1 [Homo sapiens] Length = 670 Score = 42.4 bits (98), Expect = 6e-04 Identities = 50/256 (19%), Positives = 102/256 (39%), Gaps = 51/256 (19%) Query: 37 PWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN--------IIIAGPPGTGKTTSILC 88 PWV+KY+P +E+ ++ + +E + + + ++I GPPG GKTT++ Sbjct: 79 PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKI 138 Query: 89 LAR-------ALLGPALKDAMLE-----LNASNDRGIDVVRNKIKMFAQQKVTLPKGR-- 134 L++ + P L D + N + + +++I +F + + K Sbjct: 139 LSKEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKL 198 Query: 135 ----------HKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKII------ 178 KII++++ + L + Y + R L SD + Sbjct: 199 QMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFIISDSLSGDNNQR 258 Query: 179 ----EPIQSRCAV--LRYTKLTDAQILTRLMNVIEKE------RVPYTD-DGLEAIIFTA 225 + IQ C++ + + + ++ L ++ E ++ D LE + Sbjct: 259 LLFPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGC 318 Query: 226 QGDMRQALNNLQSTFS 241 GD+R A+N+LQ + S Sbjct: 319 SGDIRSAINSLQFSSS 334 >gi|19718784 RAD17 homolog isoform 1 [Homo sapiens] Length = 670 Score = 42.4 bits (98), Expect = 6e-04 Identities = 50/256 (19%), Positives = 102/256 (39%), Gaps = 51/256 (19%) Query: 37 PWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN--------IIIAGPPGTGKTTSILC 88 PWV+KY+P +E+ ++ + +E + + + ++I GPPG GKTT++ Sbjct: 79 PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKI 138 Query: 89 LAR-------ALLGPALKDAMLE-----LNASNDRGIDVVRNKIKMFAQQKVTLPKGR-- 134 L++ + P L D + N + + +++I +F + + K Sbjct: 139 LSKEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKL 198 Query: 135 ----------HKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKII------ 178 KII++++ + L + Y + R L SD + Sbjct: 199 QMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFIISDSLSGDNNQR 258 Query: 179 ----EPIQSRCAV--LRYTKLTDAQILTRLMNVIEKE------RVPYTD-DGLEAIIFTA 225 + IQ C++ + + + ++ L ++ E ++ D LE + Sbjct: 259 LLFPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGC 318 Query: 226 QGDMRQALNNLQSTFS 241 GD+R A+N+LQ + S Sbjct: 319 SGDIRSAINSLQFSSS 334 >gi|4506383 RAD17 homolog isoform 1 [Homo sapiens] Length = 670 Score = 42.4 bits (98), Expect = 6e-04 Identities = 50/256 (19%), Positives = 102/256 (39%), Gaps = 51/256 (19%) Query: 37 PWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN--------IIIAGPPGTGKTTSILC 88 PWV+KY+P +E+ ++ + +E + + + ++I GPPG GKTT++ Sbjct: 79 PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKI 138 Query: 89 LAR-------ALLGPALKDAMLE-----LNASNDRGIDVVRNKIKMFAQQKVTLPKGR-- 134 L++ + P L D + N + + +++I +F + + K Sbjct: 139 LSKEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKL 198 Query: 135 ----------HKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKII------ 178 KII++++ + L + Y + R L SD + Sbjct: 199 QMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFIISDSLSGDNNQR 258 Query: 179 ----EPIQSRCAV--LRYTKLTDAQILTRLMNVIEKE------RVPYTD-DGLEAIIFTA 225 + IQ C++ + + + ++ L ++ E ++ D LE + Sbjct: 259 LLFPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGC 318 Query: 226 QGDMRQALNNLQSTFS 241 GD+R A+N+LQ + S Sbjct: 319 SGDIRSAINSLQFSSS 334 >gi|19718786 RAD17 homolog isoform 2 [Homo sapiens] Length = 681 Score = 42.4 bits (98), Expect = 6e-04 Identities = 50/256 (19%), Positives = 102/256 (39%), Gaps = 51/256 (19%) Query: 37 PWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN--------IIIAGPPGTGKTTSILC 88 PWV+KY+P +E+ ++ + +E + + + ++I GPPG GKTT++ Sbjct: 90 PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKI 149 Query: 89 LAR-------ALLGPALKDAMLE-----LNASNDRGIDVVRNKIKMFAQQKVTLPKGR-- 134 L++ + P L D + N + + +++I +F + + K Sbjct: 150 LSKEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKL 209 Query: 135 ----------HKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKII------ 178 KII++++ + L + Y + R L SD + Sbjct: 210 QMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFIISDSLSGDNNQR 269 Query: 179 ----EPIQSRCAV--LRYTKLTDAQILTRLMNVIEKE------RVPYTD-DGLEAIIFTA 225 + IQ C++ + + + ++ L ++ E ++ D LE + Sbjct: 270 LLFPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGC 329 Query: 226 QGDMRQALNNLQSTFS 241 GD+R A+N+LQ + S Sbjct: 330 SGDIRSAINSLQFSSS 345 >gi|4502703 cell division cycle 6 protein [Homo sapiens] Length = 560 Score = 37.4 bits (85), Expect = 0.021 Identities = 50/208 (24%), Positives = 89/208 (42%), Gaps = 56/208 (26%) Query: 71 NIIIAGPPGTGKTTSILCLARAL-------------------------LGPALKDAMLEL 105 ++ ++G PGTGKT CL+R L + PA+ + + Sbjct: 197 SLYLSGAPGTGKTA---CLSRILQDLKKELKGFKTIMLNCMSLRTAQAVFPAIAQEICQE 253 Query: 106 NASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTME------ 159 S G D++R ++ +T KG +++LDE D + Q L E Sbjct: 254 EVSRPAGKDMMRK-----LEKHMTAEKGPMIVLVLDEMDQLDSKGQDVLYTLFEWPWLSN 308 Query: 160 IYSKTTRFALACNASDKIIEPIQSR--C--AVLRYTKLTDAQILTRL---MNVIEKERVP 212 + A + +D+I+ +Q+R C +L + T QI+T L +N + +++V Sbjct: 309 SHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLNQVSRDQV- 367 Query: 213 YTDDGLEAIIFTAQ------GDMRQALN 234 D+ A+ F A+ GD+R+AL+ Sbjct: 368 -LDNA--AVQFCARKVSAVSGDVRKALD 392 >gi|22749187 putative adenylate kinase-like protein C9orf98 [Homo sapiens] Length = 479 Score = 35.4 bits (80), Expect = 0.078 Identities = 36/123 (29%), Positives = 55/123 (44%), Gaps = 19/123 (15%) Query: 68 NVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKIKMFAQQK 127 NVP I+I GPP +GKTT + L + L L L LN + + R ++ Q+K Sbjct: 56 NVPRIVILGPPASGKTTIAMWLCKHLNSSLLTLENLILNEFSYTATEARR----LYLQRK 111 Query: 128 VTLPKGRHKIII---LDEADSMTDG---------AQQALRRTMEIYSKTTRFALACNASD 175 T+P +I L E D + G +QALR ++ T R + +A D Sbjct: 112 -TVPSALLVQLIQERLAEEDCIKQGWILDGIPETREQALR--IQTLGITPRHVIVLSAPD 168 Query: 176 KII 178 ++ Sbjct: 169 TVL 171 >gi|7242140 ClpX caseinolytic protease X homolog [Homo sapiens] Length = 633 Score = 35.4 bits (80), Expect = 0.078 Identities = 27/102 (26%), Positives = 41/102 (40%), Gaps = 13/102 (12%) Query: 71 NIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKIKMFAQQKVTL 130 NI++ GP G+GKT LA+ L P L + G D+ K+ + Sbjct: 288 NILLLGPTGSGKTLLAQTLAKCLDVPFAICDCTTLTQAGYVGEDIESVIAKLLQDANYNV 347 Query: 131 PKGRHKIIILDEADSM-------------TDGAQQALRRTME 159 K + I+ LDE D + +G QQ L + +E Sbjct: 348 EKAQQGIVFLDEVDKIGSVPGIHQLRDVGGEGVQQGLLKLLE 389 >gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens] Length = 750 Score = 35.4 bits (80), Expect = 0.078 Identities = 35/115 (30%), Positives = 53/115 (46%), Gaps = 18/115 (15%) Query: 45 VKLNEIVGNEDTVSRL----------EVFAREGNVP--NIIIAGPPGTGKTTSILCLARA 92 VK ++ GN+ T+ + EV+ G VP +++ GPPG GKT +A Sbjct: 156 VKFEDVGGNDMTLKEVCKMLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIAGE 215 Query: 93 LLGPALKDAMLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMT 147 L P LK A E+ S G K++ +Q V+ II +DE D++T Sbjct: 216 LDLPILKVAAPEI-VSGVSGES--EQKLRELFEQAVS---NAPCIIFIDEIDAIT 264 >gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens] Length = 856 Score = 35.4 bits (80), Expect = 0.078 Identities = 35/115 (30%), Positives = 53/115 (46%), Gaps = 18/115 (15%) Query: 45 VKLNEIVGNEDTVSRL----------EVFAREGNVP--NIIIAGPPGTGKTTSILCLARA 92 VK ++ GN+ T+ + EV+ G VP +++ GPPG GKT +A Sbjct: 262 VKFEDVGGNDMTLKEVCKMLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIAGE 321 Query: 93 LLGPALKDAMLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMT 147 L P LK A E+ S G K++ +Q V+ II +DE D++T Sbjct: 322 LDLPILKVAAPEI-VSGVSGES--EQKLRELFEQAVS---NAPCIIFIDEIDAIT 370 >gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens] Length = 1844 Score = 34.7 bits (78), Expect = 0.13 Identities = 28/135 (20%), Positives = 53/135 (39%), Gaps = 45/135 (33%) Query: 31 AGHYELPWVEKYRPVKLNEIVGNEDTVSRLEVFARE------------------------ 66 +G ++ W EKY+P +E++GNE + +L + ++ Sbjct: 1047 SGTEDMLWTEKYQPQTASELIGNELAIKKLHSWLKDWKRRAELEERQNLKGKRDEKHEDF 1106 Query: 67 -GNVP---------------NIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASND 110 G + ++I GP G GKT ++ A+ L + E+NAS+ Sbjct: 1107 SGGIDFKGSSDDEEESRLCNTVLITGPTGVGKTAAVYACAQ-----ELGFKIFEVNASSQ 1161 Query: 111 RGIDVVRNKIKMFAQ 125 R + +++K Q Sbjct: 1162 RSGRQILSQLKEATQ 1176 >gi|31742536 fidgetin-like 1 [Homo sapiens] Length = 674 Score = 34.7 bits (78), Expect = 0.13 Identities = 43/173 (24%), Positives = 73/173 (42%), Gaps = 24/173 (13%) Query: 67 GNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNAS-NDRGIDVVRNKIKMFAQ 125 G I++ GPPGTGKT C+A + L + G +VR +FA Sbjct: 432 GPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVR---ALFAV 488 Query: 126 QKVTLPKGRHKIIILDEADSMT----DGAQQALRR-----TMEIYSKTTR------FALA 170 + P +I +DE DS+ DG ++ RR +++ TT A Sbjct: 489 ARCQQP----AVIFIDEIDSLLSQRGDGEHESSRRIKTEFLVQLDGATTSSEDRILVVGA 544 Query: 171 CNASDKIIEPIQSRCAVLRYTKLTDAQILTRL-MNVIEKERVPYTDDGLEAII 222 N +I E + R Y L +A ++ +N++ KE+ +++ +E I+ Sbjct: 545 TNRPQEIDEAARRRLVKRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIV 597 >gi|112789543 fidgetin-like 1 [Homo sapiens] Length = 674 Score = 34.7 bits (78), Expect = 0.13 Identities = 43/173 (24%), Positives = 73/173 (42%), Gaps = 24/173 (13%) Query: 67 GNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNAS-NDRGIDVVRNKIKMFAQ 125 G I++ GPPGTGKT C+A + L + G +VR +FA Sbjct: 432 GPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVR---ALFAV 488 Query: 126 QKVTLPKGRHKIIILDEADSMT----DGAQQALRR-----TMEIYSKTTR------FALA 170 + P +I +DE DS+ DG ++ RR +++ TT A Sbjct: 489 ARCQQP----AVIFIDEIDSLLSQRGDGEHESSRRIKTEFLVQLDGATTSSEDRILVVGA 544 Query: 171 CNASDKIIEPIQSRCAVLRYTKLTDAQILTRL-MNVIEKERVPYTDDGLEAII 222 N +I E + R Y L +A ++ +N++ KE+ +++ +E I+ Sbjct: 545 TNRPQEIDEAARRRLVKRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIV 597 >gi|21327685 YME1-like 1 isoform 1 [Homo sapiens] Length = 773 Score = 34.3 bits (77), Expect = 0.17 Identities = 33/105 (31%), Positives = 47/105 (44%), Gaps = 20/105 (19%) Query: 67 GNVPN-IIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDR-----GIDVVRNKI 120 G +P I++ GPPGTGKT LARA+ G A + D G +RN Sbjct: 369 GKLPKGILLVGPPGTGKT----LLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRN-- 422 Query: 121 KMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTT 165 +F + K P +I +DE DS+ + + M YS+ T Sbjct: 423 -LFREAKANAP----CVIFIDELDSV---GGKRIESPMHPYSRQT 459 >gi|7657689 YME1-like 1 isoform 3 [Homo sapiens] Length = 716 Score = 34.3 bits (77), Expect = 0.17 Identities = 33/105 (31%), Positives = 47/105 (44%), Gaps = 20/105 (19%) Query: 67 GNVPN-IIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDR-----GIDVVRNKI 120 G +P I++ GPPGTGKT LARA+ G A + D G +RN Sbjct: 312 GKLPKGILLVGPPGTGKT----LLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRN-- 365 Query: 121 KMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTT 165 +F + K P +I +DE DS+ + + M YS+ T Sbjct: 366 -LFREAKANAP----CVIFIDELDSV---GGKRIESPMHPYSRQT 402 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.135 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,941,397 Number of Sequences: 37866 Number of extensions: 546697 Number of successful extensions: 1699 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 23 Number of HSP's successfully gapped in prelim test: 53 Number of HSP's that attempted gapping in prelim test: 1622 Number of HSP's gapped (non-prelim): 101 length of query: 354 length of database: 18,247,518 effective HSP length: 103 effective length of query: 251 effective length of database: 14,347,320 effective search space: 3601177320 effective search space used: 3601177320 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.