Guide to the Human Genome
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Name: PNKP Sequence: fasta or formatted (521aa) NCBI GI: 31543419
Description:

polynucleotide kinase 3' phosphatase

Referenced in:

DNases, Recombination, and DNA Repair

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.4         44           2
 C cysteine            1.7          9           1
 D aspartate           4.2         22           1
 E glutamate           6.9         36           2
 F phenylalanine       4.6         24           2
 G glycine             9.0         47           2
 H histidine           1.3          7           1
 I isoleucine          2.5         13           1
 K lysine              5.4         28           3
 L leucine            10.2         53           2
 M methionine          1.3          7           1
 N asparagine          2.5         13           2
 P proline             8.4         44           2
 Q glutamine           3.5         18           1
 R arginine            6.9         36           1
 S serine              5.4         28           2
 T threonine           6.7         35           2
 V valine              7.5         39           3
 W tryptophan          1.7          9           1
 Y tyrosine            1.7          9           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   polynucleotide kinase 3' phosphatase 
APTX                  0.043   aprataxin isoform a 
APTX                  0.043   aprataxin isoform b 
APLF                  0.010   aprataxin and PNKP like factor 
HNRNPU                0.009   heterogeneous nuclear ribonucleoprotein U isoform b ...
HNRNPU                0.009   heterogeneous nuclear ribonucleoprotein U isoform a ...
DHX34                 0.007   DEAH (Asp-Glu-Ala-His) box polypeptide 34 
ZNF200                0.005   zinc finger protein 200 isoform 3 
ZNF200                0.005   zinc finger protein 200 isoform 3 
ZNF200                0.005   zinc finger protein 200 isoform 3 
LMTK3                 0.005   lemur tyrosine kinase 3 
DTX1                  0.005   deltex homolog 1 
MAP4K4                0.005   mitogen-activated protein kinase kinase kinase kinas...
MAP4K4                0.005   mitogen-activated protein kinase kinase kinase kinas...
MAP4K4                0.005   mitogen-activated protein kinase kinase kinase kinas...
GALNT10               0.005   GalNAc transferase 10 isoform a 
LILRB5                0.005   leukocyte immunoglobulin-like receptor, subfamily B...
LILRB5                0.005   leukocyte immunoglobulin-like receptor, subfamily B...
LILRB5                0.005   leukocyte immunoglobulin-like receptor, subfamily B, ...
LOC100132015          0.005   PREDICTED: similar to testis expressed sequence 13A...
LOC100132015          0.005   PREDICTED: similar to testis expressed sequence 13A...
LOC100132015          0.005   PREDICTED: similar to testis expressed sequence 13A...
ATP1A2                0.005   Na+/K+ -ATPase alpha 2 subunit proprotein 
CMPK1                 0.005   UMP-CMP kinase 1 isoform a 
MINK1                 0.005   misshapen/NIK-related kinase isoform 4 
MINK1                 0.005   misshapen/NIK-related kinase isoform 3 
PBXIP1                0.005   pre-B-cell leukemia homeobox interacting protein 1 [...
HNRNPUL1              0.004   heterogeneous nuclear ribonucleoprotein U-like 1 iso...
HNRNPUL1              0.004   heterogeneous nuclear ribonucleoprotein U-like 1 iso...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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