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Search of human proteins with 31543198
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31543198 serine/threonine kinase 40 [Homo sapiens]
(435 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31543198 serine/threonine kinase 40 [Homo sapiens] 865 0.0
gi|13399328 G-protein-coupled receptor induced protein [Homo sap... 121 1e-27
gi|11056054 tribbles homolog 2 [Homo sapiens] 115 6e-26
gi|7662170 AMPK-related protein kinase 5 [Homo sapiens] 115 6e-26
gi|46877068 AMP-activated protein kinase alpha 2 catalytic subun... 107 3e-23
gi|31542265 tribbles 3 [Homo sapiens] 106 5e-23
gi|4502023 AKT2 kinase [Homo sapiens] 102 5e-22
gi|94557301 protein kinase, AMP-activated, alpha 1 catalytic sub... 102 5e-22
gi|7661974 maternal embryonic leucine zipper kinase [Homo sapiens] 102 9e-22
gi|38569460 SNF1-like kinase 2 [Homo sapiens] 101 2e-21
gi|13569922 NUAK family, SNF1-like kinase, 2 [Homo sapiens] 101 2e-21
gi|14150045 calcium/calmodulin-dependent protein kinase 1 alpha ... 100 3e-21
gi|148806859 calcium/calmodulin-dependent protein kinase 1 alpha... 100 3e-21
gi|27437011 calcium/calmodulin-dependent protein kinase 1 alpha ... 100 3e-21
gi|38569491 serine/threonine-protein kinase QSK [Homo sapiens] 99 6e-21
gi|24308326 BR serine/threonine kinase 1 [Homo sapiens] 99 8e-21
gi|94557299 protein kinase, AMP-activated, alpha 1 catalytic sub... 98 1e-20
gi|83776596 CaM kinase-like vesicle-associated [Homo sapiens] 98 2e-20
gi|4885549 AKT3 kinase isoform 1 [Homo sapiens] 97 2e-20
gi|32307163 AKT3 kinase isoform 2 [Homo sapiens] 97 2e-20
gi|33636756 MAP/microtubule affinity-regulating kinase 4 [Homo s... 97 2e-20
gi|25952118 calcium/calmodulin-dependent protein kinase II alpha... 97 4e-20
gi|25952114 calcium/calmodulin-dependent protein kinase II alpha... 97 4e-20
gi|27437025 calcium/calmodulin-dependent protein kinase kinase 2... 96 5e-20
gi|193083129 MAP/microtubule affinity-regulating kinase 3 isofor... 96 5e-20
gi|4505785 phosphorylase kinase, gamma 2 (testis) [Homo sapiens] 96 5e-20
gi|26667199 calcium/calmodulin-dependent protein kinase II gamma... 96 6e-20
gi|62241015 AKT1 kinase [Homo sapiens] 96 6e-20
gi|62241013 AKT1 kinase [Homo sapiens] 96 6e-20
gi|62241011 AKT1 kinase [Homo sapiens] 96 6e-20
>gi|31543198 serine/threonine kinase 40 [Homo sapiens]
Length = 435
Score = 865 bits (2236), Expect = 0.0
Identities = 435/435 (100%), Positives = 435/435 (100%)
Query: 1 MKRRASDRGAGETSARAKALGSGISGNNAKRAGPFILGPRLGNSPVPSIVQCLARKDGTD 60
MKRRASDRGAGETSARAKALGSGISGNNAKRAGPFILGPRLGNSPVPSIVQCLARKDGTD
Sbjct: 1 MKRRASDRGAGETSARAKALGSGISGNNAKRAGPFILGPRLGNSPVPSIVQCLARKDGTD 60
Query: 61 DFYQLKILTLEERGDQGIESQEERQGKMLLHTEYSLLSLLHTQDGVVHHHGLFQDRTCEI 120
DFYQLKILTLEERGDQGIESQEERQGKMLLHTEYSLLSLLHTQDGVVHHHGLFQDRTCEI
Sbjct: 61 DFYQLKILTLEERGDQGIESQEERQGKMLLHTEYSLLSLLHTQDGVVHHHGLFQDRTCEI 120
Query: 121 VEDTESSRMVKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYD 180
VEDTESSRMVKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYD
Sbjct: 121 VEDTESSRMVKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYD 180
Query: 181 VVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYI 240
VVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYI
Sbjct: 181 VVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYI 240
Query: 241 SPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVS 300
SPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVS
Sbjct: 241 SPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVS 300
Query: 301 ENTVCLIRKLLVLDPQQRLAAADVLEALSAIIASWQSLSSLSGPLQVVPDIDDQMSNADS 360
ENTVCLIRKLLVLDPQQRLAAADVLEALSAIIASWQSLSSLSGPLQVVPDIDDQMSNADS
Sbjct: 301 ENTVCLIRKLLVLDPQQRLAAADVLEALSAIIASWQSLSSLSGPLQVVPDIDDQMSNADS 360
Query: 361 SQEAKVTEECSQYEFENYMRQQLLLAEEKSSIHDARSWVPKRQFGSAPPVRRLGHDAQPM 420
SQEAKVTEECSQYEFENYMRQQLLLAEEKSSIHDARSWVPKRQFGSAPPVRRLGHDAQPM
Sbjct: 361 SQEAKVTEECSQYEFENYMRQQLLLAEEKSSIHDARSWVPKRQFGSAPPVRRLGHDAQPM 420
Query: 421 TSLDTAILAQRYLRK 435
TSLDTAILAQRYLRK
Sbjct: 421 TSLDTAILAQRYLRK 435
>gi|13399328 G-protein-coupled receptor induced protein [Homo
sapiens]
Length = 372
Score = 121 bits (304), Expect = 1e-27
Identities = 71/182 (39%), Positives = 102/182 (56%), Gaps = 6/182 (3%)
Query: 146 AHDFSDKTADLINLQHYVIKEKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVL 205
A+ F +K D ++ YV KRL E E +F +V V HQ IV DLKL V
Sbjct: 156 AYVFFEK--DFGDMHSYVRSRKRLREEEAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVF 213
Query: 206 NKRTHRITITNFCLGKHLVS-EGDLLKDQRGSPAYISPDVLSGR-PYRGKPSDMWALGVV 263
+ H++ E D L D+ G PAY+SP++L+ Y GK +D+W+LGV+
Sbjct: 214 STEERTQLRLESLEDTHIMKGEDDALSDKHGCPAYVSPEILNTTGTYSGKAADVWSLGVM 273
Query: 264 LFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAAD 323
L+T+L G++PF+DS P LF KI+ ++ IPE +S CLIR LL +P +RL A +
Sbjct: 274 LYTLLVGRYPFHDSDPSALFSKIRRGQFCIPE--HISPKARCLIRSLLRREPSERLTAPE 331
Query: 324 VL 325
+L
Sbjct: 332 IL 333
>gi|11056054 tribbles homolog 2 [Homo sapiens]
Length = 343
Score = 115 bits (289), Expect = 6e-26
Identities = 66/201 (32%), Positives = 108/201 (53%), Gaps = 19/201 (9%)
Query: 143 CLCAHDFSDKTADLI---------------NLQHYVIKEKRLSERETVVIFYDVVRVVEA 187
CL AH ++ ++I ++ +V K+L E E +FY + V
Sbjct: 106 CLSAHSNINQITEIILGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFYQIASAVAH 165
Query: 188 LHQKNIVHRDLKLGNMVL-NKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYISPDVLS 246
H +V RDLKL + ++ R+ + + L + D L D+ G PAY+SP++L+
Sbjct: 166 CHDGGLVLRDLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILN 225
Query: 247 -GRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVSENTVC 305
Y GK +D+W+LGV+L+TML G++PF+D P LF KI+ ++ IPE +S C
Sbjct: 226 TSGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPE--TLSPKAKC 283
Query: 306 LIRKLLVLDPQQRLAAADVLE 326
LIR +L +P +RL + ++L+
Sbjct: 284 LIRSILRREPSERLTSQEILD 304
>gi|7662170 AMPK-related protein kinase 5 [Homo sapiens]
Length = 661
Score = 115 bits (289), Expect = 6e-26
Identities = 68/169 (40%), Positives = 99/169 (58%), Gaps = 11/169 (6%)
Query: 159 LQHYVIKEKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFC 218
L Y+ + +RLSERET F +V V H+ +VHRDLKL N++L+ + I I +F
Sbjct: 140 LYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCN-IKIADFG 198
Query: 219 LGKHLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSI 278
L +L + L+ GSP Y SP++++GRPYRG D WALGV+L+T++YG PF
Sbjct: 199 LS-NLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLVYGTMPFDGFD 257
Query: 279 PQELFRKIKAAEY---TIPEDGRVSENTVCLIRKLLVLDPQQRLAAADV 324
+ L R+I + EY T P D R LIR +L+++P +R D+
Sbjct: 258 HKNLIRQISSGEYREPTQPSDAR------GLIRWMLMVNPDRRATIEDI 300
>gi|46877068 AMP-activated protein kinase alpha 2 catalytic subunit
[Homo sapiens]
Length = 552
Score = 107 bits (266), Expect = 3e-23
Identities = 69/218 (31%), Positives = 114/218 (52%), Gaps = 14/218 (6%)
Query: 162 YVIKEKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGK 221
Y+ K R+ E E +F ++ V+ H+ +VHRDLK N++L+ + I +F L
Sbjct: 104 YICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNA-KIADFGLS- 161
Query: 222 HLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQE 281
+++S+G+ L+ GSP Y +P+V+SGR Y G D+W+ GV+L+ +L G PF D
Sbjct: 162 NMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPT 221
Query: 282 LFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAADVLEALSAIIASW--QSLS 339
LF+KI+ + IPE ++ + L+ +L +DP +R D+ E W Q L
Sbjct: 222 LFKKIRGGVFYIPE--YLNRSVATLLMHMLQVDPLKRATIKDIRE------HEWFKQDLP 273
Query: 340 SLSGPLQVVPDIDDQMSNADSSQEAKVTEECSQYEFEN 377
S P P D + + ++ +E EC++ E N
Sbjct: 274 SYLFPED--PSYDANVIDDEAVKEVCEKFECTESEVMN 309
>gi|31542265 tribbles 3 [Homo sapiens]
Length = 358
Score = 106 bits (264), Expect = 5e-23
Identities = 63/168 (37%), Positives = 92/168 (54%), Gaps = 5/168 (2%)
Query: 161 HYVIKEK-RLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVL-NKRTHRITITNFC 218
H +++ + R+ E E V+F + + HQ +V RDLKL V ++ ++ + N
Sbjct: 145 HSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLE 204
Query: 219 LGKHLVSEGDLLKDQRGSPAYISPDVLSGR-PYRGKPSDMWALGVVLFTMLYGQFPFYDS 277
L D L D+ PAY+ P++LS R Y GK +D+W+LGV LFTML G +PF DS
Sbjct: 205 DSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDS 264
Query: 278 IPQELFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAADVL 325
P LF KI+ Y +P +S CL+R LL +P +RL A +L
Sbjct: 265 EPVLLFGKIRRGAYALP--AGLSAPARCLVRCLLRREPAERLTATGIL 310
>gi|4502023 AKT2 kinase [Homo sapiens]
Length = 481
Score = 102 bits (255), Expect = 5e-22
Identities = 62/182 (34%), Positives = 101/182 (55%), Gaps = 9/182 (4%)
Query: 162 YVIKEKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGK 221
++ +E+ +E ++V +E LH +++V+RD+KL N++L+K H I IT+F L K
Sbjct: 240 HLSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGH-IKITDFGLCK 298
Query: 222 HLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQE 281
+S+G +K G+P Y++P+VL Y G+ D W LGVV++ M+ G+ PFY+ +
Sbjct: 299 EGISDGATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHER 357
Query: 282 LFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLA-----AADVLEALSAIIASWQ 336
LF I E P +S L+ LL DP+QRL A +V+E + +WQ
Sbjct: 358 LFELILMEEIRFPR--TLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQ 415
Query: 337 SL 338
+
Sbjct: 416 DV 417
>gi|94557301 protein kinase, AMP-activated, alpha 1 catalytic
subunit isoform 1 [Homo sapiens]
Length = 559
Score = 102 bits (255), Expect = 5e-22
Identities = 56/165 (33%), Positives = 97/165 (58%), Gaps = 4/165 (2%)
Query: 162 YVIKEKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGK 221
Y+ K RL E+E+ +F ++ V+ H+ +VHRDLK N++L+ + I +F L
Sbjct: 115 YICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNA-KIADFGLS- 172
Query: 222 HLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQE 281
+++S+G+ L+ GSP Y +P+V+SGR Y G D+W+ GV+L+ +L G PF D
Sbjct: 173 NMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPT 232
Query: 282 LFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAADVLE 326
LF+KI + P+ ++ + + L++ +L +DP +R D+ E
Sbjct: 233 LFKKICDGIFYTPQ--YLNPSVISLLKHMLQVDPMKRATIKDIRE 275
>gi|7661974 maternal embryonic leucine zipper kinase [Homo sapiens]
Length = 651
Score = 102 bits (253), Expect = 9e-22
Identities = 52/165 (31%), Positives = 101/165 (61%), Gaps = 4/165 (2%)
Query: 162 YVIKEKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGK 221
Y+I + RLSE ET V+F +V V +H + HRDLK N++ ++ H++ + +F L
Sbjct: 97 YIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEY-HKLKLIDFGLCA 155
Query: 222 HLVSEGDL-LKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQ 280
D L+ GS AY +P+++ G+ Y G +D+W++G++L+ ++ G PF D
Sbjct: 156 KPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVM 215
Query: 281 ELFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAADVL 325
L++KI +Y +P+ +S +++ L++++L +DP++R++ ++L
Sbjct: 216 ALYKKIMRGKYDVPK--WLSPSSILLLQQMLQVDPKKRISMKNLL 258
>gi|38569460 SNF1-like kinase 2 [Homo sapiens]
Length = 926
Score = 101 bits (251), Expect = 2e-21
Identities = 60/165 (36%), Positives = 92/165 (55%), Gaps = 4/165 (2%)
Query: 162 YVIKEKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGK 221
Y+ RL+E E F+ ++ V+ H + IVHRDLK N++L+ + I I +F G
Sbjct: 107 YLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMN-IKIADFGFGN 165
Query: 222 HLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQE 281
S G+LL GSP Y +P+V G+ Y G D+W++GVVL+ ++ G PF
Sbjct: 166 FFKS-GELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPI 224
Query: 282 LFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAADVLE 326
L +++ + IP +SE+ LIR++LVLDP +RL A + E
Sbjct: 225 LRQRVLEGRFRIPY--FMSEDCEHLIRRMLVLDPSKRLTIAQIKE 267
>gi|13569922 NUAK family, SNF1-like kinase, 2 [Homo sapiens]
Length = 628
Score = 101 bits (251), Expect = 2e-21
Identities = 60/167 (35%), Positives = 94/167 (56%), Gaps = 5/167 (2%)
Query: 158 NLQHYVIKEKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNF 217
+L Y+ + ++LSERE F +V V HQ +VHRDLKL N++L+ + I I +F
Sbjct: 136 DLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGN-IKIADF 194
Query: 218 CLGKHLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDS 277
L +L +G L+ GSP Y SP++++G+PY G D W+LGV+L+ +++G PF
Sbjct: 195 GLS-NLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGH 253
Query: 278 IPQELFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAADV 324
+ L ++I Y P + LIR LL+++P +R DV
Sbjct: 254 DHKILVKQISNGAYREPPK---PSDACGLIRWLLMVNPTRRATLEDV 297
>gi|14150045 calcium/calmodulin-dependent protein kinase 1 alpha
isoform a [Homo sapiens]
Length = 505
Score = 100 bits (248), Expect = 3e-21
Identities = 55/161 (34%), Positives = 86/161 (53%), Gaps = 3/161 (1%)
Query: 166 EKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVS 225
+K SE + + DV+ +E LH + IVHRD+K N++L H + I +F +
Sbjct: 244 DKPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGH-VKIADFGVSNQFEG 302
Query: 226 EGDLLKDQRGSPAYISPDVLS--GRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELF 283
L G+PA+++P+ +S G+ + GK D+WA GV L+ +YG+ PF D L
Sbjct: 303 NDAQLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALH 362
Query: 284 RKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAADV 324
RKIK PE+ +SE LI K+L +P+ R+ D+
Sbjct: 363 RKIKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDI 403
>gi|148806859 calcium/calmodulin-dependent protein kinase 1 alpha
isoform b [Homo sapiens]
Length = 520
Score = 100 bits (248), Expect = 3e-21
Identities = 55/161 (34%), Positives = 86/161 (53%), Gaps = 3/161 (1%)
Query: 166 EKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVS 225
+K SE + + DV+ +E LH + IVHRD+K N++L H + I +F +
Sbjct: 282 DKPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGH-VKIADFGVSNQFEG 340
Query: 226 EGDLLKDQRGSPAYISPDVLS--GRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELF 283
L G+PA+++P+ +S G+ + GK D+WA GV L+ +YG+ PF D L
Sbjct: 341 NDAQLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALH 400
Query: 284 RKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAADV 324
RKIK PE+ +SE LI K+L +P+ R+ D+
Sbjct: 401 RKIKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDI 441
>gi|27437011 calcium/calmodulin-dependent protein kinase 1 alpha
isoform a [Homo sapiens]
Length = 505
Score = 100 bits (248), Expect = 3e-21
Identities = 55/161 (34%), Positives = 86/161 (53%), Gaps = 3/161 (1%)
Query: 166 EKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVS 225
+K SE + + DV+ +E LH + IVHRD+K N++L H + I +F +
Sbjct: 244 DKPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGH-VKIADFGVSNQFEG 302
Query: 226 EGDLLKDQRGSPAYISPDVLS--GRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELF 283
L G+PA+++P+ +S G+ + GK D+WA GV L+ +YG+ PF D L
Sbjct: 303 NDAQLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALH 362
Query: 284 RKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAADV 324
RKIK PE+ +SE LI K+L +P+ R+ D+
Sbjct: 363 RKIKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDI 403
>gi|38569491 serine/threonine-protein kinase QSK [Homo sapiens]
Length = 1263
Score = 99.4 bits (246), Expect = 6e-21
Identities = 60/165 (36%), Positives = 94/165 (56%), Gaps = 8/165 (4%)
Query: 162 YVIKEKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGK 221
+++ R++E+E F +V V H +NIVHRDLK N++L+ + I I +F
Sbjct: 95 HLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLN-IKIADFGFS- 152
Query: 222 HLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQE 281
+L + G LLK GSP Y +P++ G+ Y G D+W+LGVVL+ ++ G PF S Q
Sbjct: 153 NLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQN 212
Query: 282 LFRKIKAAEYTIPEDGRVSENTVC--LIRKLLVLDPQQRLAAADV 324
L ++ + ++ IP +T C LIR +LVLDP +RL+ +
Sbjct: 213 LRARVLSGKFRIP----FFMSTECEHLIRHMLVLDPNKRLSMEQI 253
>gi|24308326 BR serine/threonine kinase 1 [Homo sapiens]
Length = 778
Score = 99.0 bits (245), Expect = 8e-21
Identities = 59/195 (30%), Positives = 106/195 (54%), Gaps = 14/195 (7%)
Query: 130 VKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYDVVRVVEALH 189
V + KK + LVL+ + + D Y++K+ RL+ +E F +V ++ H
Sbjct: 99 VYENKKYLYLVLEHVSGGELFD----------YLVKKGRLTPKEARKFFRQIVSALDFCH 148
Query: 190 QKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYISPDVLSGRP 249
+I HRDLK N++L+++ + I I +F + V + LL+ GSP Y P+V+ G
Sbjct: 149 SYSICHRDLKPENLLLDEKNN-IRIADFGMASLQVGDS-LLETSCGSPHYACPEVIKGEK 206
Query: 250 YRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVSENTVCLIRK 309
Y G+ +DMW+ GV+LF +L G PF D ++L K+K + +P + + L+R
Sbjct: 207 YDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPH--FIPPDCQSLLRG 264
Query: 310 LLVLDPQQRLAAADV 324
++ ++P++RL+ +
Sbjct: 265 MIEVEPEKRLSLEQI 279
>gi|94557299 protein kinase, AMP-activated, alpha 1 catalytic
subunit isoform 2 [Homo sapiens]
Length = 574
Score = 98.2 bits (243), Expect = 1e-20
Identities = 54/160 (33%), Positives = 94/160 (58%), Gaps = 4/160 (2%)
Query: 167 KRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSE 226
K L E+E+ +F ++ V+ H+ +VHRDLK N++L+ + I +F L +++S+
Sbjct: 135 KELDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNA-KIADFGLS-NMMSD 192
Query: 227 GDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKI 286
G+ L+ GSP Y +P+V+SGR Y G D+W+ GV+L+ +L G PF D LF+KI
Sbjct: 193 GEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKI 252
Query: 287 KAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAADVLE 326
+ P+ ++ + + L++ +L +DP +R D+ E
Sbjct: 253 CDGIFYTPQ--YLNPSVISLLKHMLQVDPMKRATIKDIRE 290
>gi|83776596 CaM kinase-like vesicle-associated [Homo sapiens]
Length = 501
Score = 97.8 bits (242), Expect = 2e-20
Identities = 69/218 (31%), Positives = 114/218 (52%), Gaps = 19/218 (8%)
Query: 162 YVIKEKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKR--THRITITNFCL 219
+++ + SER+T + V+ V LH IVHR+LKL N+V R +I I++F L
Sbjct: 110 WILDQGYYSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHL 169
Query: 220 GKHLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIP 279
K E L+K+ G+P Y++P+V+ GR G+P D WA+GV+++ +L G PFY+ +
Sbjct: 170 AK---LENGLIKEPCGTPEYLAPEVV-GRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVE 225
Query: 280 QE--------LFRKIKAAEYTI--PEDGRVSENTVCLIRKLLVLDPQQRLAAADVLEALS 329
++ LFRKI A +Y P +S+ L+ +L+ ++ QR+ A EA+S
Sbjct: 226 EDDYENHDKNLFRKILAGDYEFDSPYWDDISQAAKDLVTRLMEVEQDQRITAE---EAIS 282
Query: 330 AIIASWQSLSSLSGPLQVVPDIDDQMSNADSSQEAKVT 367
S + S + V I+ + A + +VT
Sbjct: 283 HEWISGNAASDKNIKDGVCAQIEKNFARAKWKKAVRVT 320
>gi|4885549 AKT3 kinase isoform 1 [Homo sapiens]
Length = 479
Score = 97.4 bits (241), Expect = 2e-20
Identities = 61/186 (32%), Positives = 101/186 (54%), Gaps = 14/186 (7%)
Query: 134 KKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYDVVRVVEALHQKNI 193
K R+C V++ + + L ++ +E+ SE T ++V ++ LH I
Sbjct: 218 KDRLCFVMEYVNGGE----------LFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKI 267
Query: 194 VHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYISPDVLSGRPYRGK 253
V+RDLKL N++L+K H I IT+F L K +++ +K G+P Y++P+VL Y G+
Sbjct: 268 VYRDLKLENLMLDKDGH-IKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDY-GR 325
Query: 254 PSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVSENTVCLIRKLLVL 313
D W LGVV++ M+ G+ PFY+ ++LF I + P +S + L+ LL+
Sbjct: 326 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--TLSSDAKSLLSGLLIK 383
Query: 314 DPQQRL 319
DP +RL
Sbjct: 384 DPNKRL 389
>gi|32307163 AKT3 kinase isoform 2 [Homo sapiens]
Length = 465
Score = 97.4 bits (241), Expect = 2e-20
Identities = 61/186 (32%), Positives = 101/186 (54%), Gaps = 14/186 (7%)
Query: 134 KKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYDVVRVVEALHQKNI 193
K R+C V++ + + L ++ +E+ SE T ++V ++ LH I
Sbjct: 218 KDRLCFVMEYVNGGE----------LFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKI 267
Query: 194 VHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYISPDVLSGRPYRGK 253
V+RDLKL N++L+K H I IT+F L K +++ +K G+P Y++P+VL Y G+
Sbjct: 268 VYRDLKLENLMLDKDGH-IKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDY-GR 325
Query: 254 PSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVSENTVCLIRKLLVL 313
D W LGVV++ M+ G+ PFY+ ++LF I + P +S + L+ LL+
Sbjct: 326 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--TLSSDAKSLLSGLLIK 383
Query: 314 DPQQRL 319
DP +RL
Sbjct: 384 DPNKRL 389
>gi|33636756 MAP/microtubule affinity-regulating kinase 4 [Homo
sapiens]
Length = 688
Score = 97.4 bits (241), Expect = 2e-20
Identities = 54/165 (32%), Positives = 89/165 (53%), Gaps = 4/165 (2%)
Query: 162 YVIKEKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGK 221
Y++ R+ E+E F +V V HQKNIVHRDLK N++L+ + I I +F
Sbjct: 146 YLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEAN-IKIADFGFSN 204
Query: 222 HLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQE 281
G L GSP Y +P++ G+ Y G D+W+LGV+L+T++ G PF +E
Sbjct: 205 EFTL-GSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKE 263
Query: 282 LFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAADVLE 326
L ++ +Y +P +S + ++R+ LVL+P +R +++
Sbjct: 264 LRERVLRGKYRVP--FYMSTDCESILRRFLVLNPAKRCTLEQIMK 306
>gi|25952118 calcium/calmodulin-dependent protein kinase II alpha
isoform 2 [Homo sapiens]
Length = 478
Score = 96.7 bits (239), Expect = 4e-20
Identities = 56/168 (33%), Positives = 89/168 (52%), Gaps = 5/168 (2%)
Query: 163 VIKEKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTH--RITITNFCLG 220
++ + SE + ++ V HQ +VHRDLK N++L + + + +F L
Sbjct: 101 IVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLA 160
Query: 221 KHLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQ 280
+ E G+P Y+SP+VL PY GKP D+WA GV+L+ +L G PF+D
Sbjct: 161 IEVEGEQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLVGYPPFWDEDQH 219
Query: 281 ELFRKIKAAEYTI--PEDGRVSENTVCLIRKLLVLDPQQRLAAADVLE 326
L+++IKA Y PE V+ LI K+L ++P +R+ AA+ L+
Sbjct: 220 RLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALK 267
>gi|25952114 calcium/calmodulin-dependent protein kinase II alpha
isoform 1 [Homo sapiens]
Length = 489
Score = 96.7 bits (239), Expect = 4e-20
Identities = 56/168 (33%), Positives = 89/168 (52%), Gaps = 5/168 (2%)
Query: 163 VIKEKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTH--RITITNFCLG 220
++ + SE + ++ V HQ +VHRDLK N++L + + + +F L
Sbjct: 101 IVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLA 160
Query: 221 KHLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQ 280
+ E G+P Y+SP+VL PY GKP D+WA GV+L+ +L G PF+D
Sbjct: 161 IEVEGEQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLVGYPPFWDEDQH 219
Query: 281 ELFRKIKAAEYTI--PEDGRVSENTVCLIRKLLVLDPQQRLAAADVLE 326
L+++IKA Y PE V+ LI K+L ++P +R+ AA+ L+
Sbjct: 220 RLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALK 267
>gi|27437025 calcium/calmodulin-dependent protein kinase kinase 2
beta isoform 3 [Homo sapiens]
Length = 545
Score = 96.3 bits (238), Expect = 5e-20
Identities = 61/218 (27%), Positives = 107/218 (49%), Gaps = 7/218 (3%)
Query: 167 KRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSE 226
K LSE + F D+++ +E LH + I+HRD+K N+++ + H I I +F +
Sbjct: 282 KPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGH-IKIADFGVSNEFKGS 340
Query: 227 GDLLKDQRGSPAYISPDVLSG--RPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFR 284
LL + G+PA+++P+ LS + + GK D+WA+GV L+ ++GQ PF D L
Sbjct: 341 DALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHS 400
Query: 285 KIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAADVLEALSAIIASWQSLSSLSGP 344
KIK+ P+ ++E+ LI ++L +P+ R+ ++ + +I S P
Sbjct: 401 KIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKILVKTMIRK----RSFGNP 456
Query: 345 LQVVPDIDDQMSNADSSQEAKVTEECSQYEFENYMRQQ 382
+ + +S + K T EC RQ+
Sbjct: 457 FEGSRREERSLSAPGNLLTKKPTRECESLSELKEARQR 494
>gi|193083129 MAP/microtubule affinity-regulating kinase 3 isoform d
[Homo sapiens]
Length = 713
Score = 96.3 bits (238), Expect = 5e-20
Identities = 70/236 (29%), Positives = 117/236 (49%), Gaps = 12/236 (5%)
Query: 162 YVIKEKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGK 221
Y++ R+ E+E F +V V+ HQK IVHRDLK N++L+ + I I +F
Sbjct: 143 YLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMN-IKIADFGFSN 201
Query: 222 HLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQE 281
+ G L GSP Y +P++ G+ Y G D+W+LGV+L+T++ G PF +E
Sbjct: 202 EF-TVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKE 260
Query: 282 LFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAADVLEALSAIIASWQSLSSL 341
L ++ +Y IP +S + L+++ LVL+P +R +++ I + L
Sbjct: 261 LRERVLRGKYRIP--FYMSTDCENLLKRFLVLNPIKRGTLEQIMK--DRWINAGHEEDEL 316
Query: 342 SGPLQVVPDIDDQ-----MSNADSSQEAKVTEECSQYEFENYMRQQLLLAEEKSSI 392
++ DI DQ M SQE ++ E S+ +++ LLL + S +
Sbjct: 317 KPFVEPELDISDQKRIDIMVGMGYSQE-EIQESLSKMKYDEITATYLLLGRKSSEV 371
>gi|4505785 phosphorylase kinase, gamma 2 (testis) [Homo sapiens]
Length = 406
Score = 96.3 bits (238), Expect = 5e-20
Identities = 62/172 (36%), Positives = 94/172 (54%), Gaps = 9/172 (5%)
Query: 162 YVIKEKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGK 221
Y+ ++ LSE+ET I ++ V LH NIVHRDLK N++L+ +I +++F
Sbjct: 118 YLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNM-QIRLSDFGFSC 176
Query: 222 HLVSEGDLLKDQRGSPAYISPDVL-----SGRPYRGKPSDMWALGVVLFTMLYGQFPFYD 276
HL G+ L++ G+P Y++P++L P GK D+WA GV+LFT+L G PF+
Sbjct: 177 HL-EPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWH 235
Query: 277 SIPQELFRKIKAAEY--TIPEDGRVSENTVCLIRKLLVLDPQQRLAAADVLE 326
+ R I +Y + PE S LI +LL +DP+ RL A L+
Sbjct: 236 RRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQ 287
>gi|26667199 calcium/calmodulin-dependent protein kinase II gamma
isoform 3 [Homo sapiens]
Length = 518
Score = 95.9 bits (237), Expect = 6e-20
Identities = 67/219 (30%), Positives = 111/219 (50%), Gaps = 19/219 (8%)
Query: 126 SSRMVKKMKK--RICLVL---------DCLCAHDFSDKTADLIN---LQHYVIKEKRLSE 171
S+R +K+++ RIC +L D + F DL+ L ++ + SE
Sbjct: 51 SARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSE 110
Query: 172 RETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTH--RITITNFCLGKHLVSEGDL 229
+ + ++ V +HQ +IVHRDLK N++L + + + +F L + E
Sbjct: 111 ADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQA 170
Query: 230 LKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAA 289
G+P Y+SP+VL PY GKP D+WA GV+L+ +L G PF+D +L+++IKA
Sbjct: 171 WFGFAGTPGYLSPEVLRKDPY-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAG 229
Query: 290 EYTI--PEDGRVSENTVCLIRKLLVLDPQQRLAAADVLE 326
Y PE V+ LI ++L ++P +R+ A L+
Sbjct: 230 AYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALK 268
>gi|62241015 AKT1 kinase [Homo sapiens]
Length = 480
Score = 95.9 bits (237), Expect = 6e-20
Identities = 58/159 (36%), Positives = 91/159 (57%), Gaps = 5/159 (3%)
Query: 162 YVIKEKRLSERETVVIFYDVVRVVEALH-QKNIVHRDLKLGNMVLNKRTHRITITNFCLG 220
++ +E+ SE ++V ++ LH +KN+V+RDLKL N++L+K H I IT+F L
Sbjct: 238 HLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGH-IKITDFGLC 296
Query: 221 KHLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQ 280
K + +G +K G+P Y++P+VL Y G+ D W LGVV++ M+ G+ PFY+ +
Sbjct: 297 KEGIKDGATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHE 355
Query: 281 ELFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRL 319
+LF I E P + L+ LL DP+QRL
Sbjct: 356 KLFELILMEEIRFPR--TLGPEAKSLLSGLLKKDPKQRL 392
>gi|62241013 AKT1 kinase [Homo sapiens]
Length = 480
Score = 95.9 bits (237), Expect = 6e-20
Identities = 58/159 (36%), Positives = 91/159 (57%), Gaps = 5/159 (3%)
Query: 162 YVIKEKRLSERETVVIFYDVVRVVEALH-QKNIVHRDLKLGNMVLNKRTHRITITNFCLG 220
++ +E+ SE ++V ++ LH +KN+V+RDLKL N++L+K H I IT+F L
Sbjct: 238 HLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGH-IKITDFGLC 296
Query: 221 KHLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQ 280
K + +G +K G+P Y++P+VL Y G+ D W LGVV++ M+ G+ PFY+ +
Sbjct: 297 KEGIKDGATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHE 355
Query: 281 ELFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRL 319
+LF I E P + L+ LL DP+QRL
Sbjct: 356 KLFELILMEEIRFPR--TLGPEAKSLLSGLLKKDPKQRL 392
>gi|62241011 AKT1 kinase [Homo sapiens]
Length = 480
Score = 95.9 bits (237), Expect = 6e-20
Identities = 58/159 (36%), Positives = 91/159 (57%), Gaps = 5/159 (3%)
Query: 162 YVIKEKRLSERETVVIFYDVVRVVEALH-QKNIVHRDLKLGNMVLNKRTHRITITNFCLG 220
++ +E+ SE ++V ++ LH +KN+V+RDLKL N++L+K H I IT+F L
Sbjct: 238 HLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGH-IKITDFGLC 296
Query: 221 KHLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQ 280
K + +G +K G+P Y++P+VL Y G+ D W LGVV++ M+ G+ PFY+ +
Sbjct: 297 KEGIKDGATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHE 355
Query: 281 ELFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRL 319
+LF I E P + L+ LL DP+QRL
Sbjct: 356 KLFELILMEEIRFPR--TLGPEAKSLLSGLLKKDPKQRL 392
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,242,381
Number of Sequences: 37866
Number of extensions: 728080
Number of successful extensions: 3279
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 421
Number of HSP's successfully gapped in prelim test: 296
Number of HSP's that attempted gapping in prelim test: 1971
Number of HSP's gapped (non-prelim): 872
length of query: 435
length of database: 18,247,518
effective HSP length: 105
effective length of query: 330
effective length of database: 14,271,588
effective search space: 4709624040
effective search space used: 4709624040
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.