Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 31542661
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31542661 transmembrane protein 57 [Homo sapiens]
(664 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31542661 transmembrane protein 57 [Homo sapiens] 1308 0.0
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 72 1e-12
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 72 1e-12
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 72 1e-12
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 72 1e-12
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 72 1e-12
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 72 1e-12
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 72 2e-12
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 72 2e-12
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 71 3e-12
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 70 5e-12
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 69 1e-11
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 69 1e-11
gi|110611218 ribosome binding protein 1 [Homo sapiens] 68 3e-11
gi|110611220 ribosome binding protein 1 [Homo sapiens] 68 3e-11
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 68 3e-11
gi|38044112 restin isoform b [Homo sapiens] 66 9e-11
gi|4506751 restin isoform a [Homo sapiens] 66 9e-11
gi|188528616 testis specific, 10 [Homo sapiens] 66 1e-10
gi|13376858 testis specific, 10 [Homo sapiens] 66 1e-10
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 66 1e-10
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 66 1e-10
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 66 1e-10
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 65 2e-10
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 65 2e-10
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 65 2e-10
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 65 2e-10
gi|71061468 centromere protein E [Homo sapiens] 64 6e-10
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 64 6e-10
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 62 2e-09
>gi|31542661 transmembrane protein 57 [Homo sapiens]
Length = 664
Score = 1308 bits (3386), Expect = 0.0
Identities = 664/664 (100%), Positives = 664/664 (100%)
Query: 1 MKRRNADCSKLRRPLKRNRITEGIYGSTFLYLKFLVVWALVLLADFVLEFRFEYLWPFWL 60
MKRRNADCSKLRRPLKRNRITEGIYGSTFLYLKFLVVWALVLLADFVLEFRFEYLWPFWL
Sbjct: 1 MKRRNADCSKLRRPLKRNRITEGIYGSTFLYLKFLVVWALVLLADFVLEFRFEYLWPFWL 60
Query: 61 FIRSVYDSFRYQGLAFSVFFVCVAFTSNIICLLFIPIQWLFFAASTYVWVQYVWHTERGV 120
FIRSVYDSFRYQGLAFSVFFVCVAFTSNIICLLFIPIQWLFFAASTYVWVQYVWHTERGV
Sbjct: 61 FIRSVYDSFRYQGLAFSVFFVCVAFTSNIICLLFIPIQWLFFAASTYVWVQYVWHTERGV 120
Query: 121 CLPTVSLWILFVYIEAAIRFKDLKNFHVDLCRPFAAHCIGYPVVTLGFGFKSYVSYKMRL 180
CLPTVSLWILFVYIEAAIRFKDLKNFHVDLCRPFAAHCIGYPVVTLGFGFKSYVSYKMRL
Sbjct: 121 CLPTVSLWILFVYIEAAIRFKDLKNFHVDLCRPFAAHCIGYPVVTLGFGFKSYVSYKMRL 180
Query: 181 RKQKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPAN 240
RKQKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPAN
Sbjct: 181 RKQKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPAN 240
Query: 241 KKLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNN 300
KKLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNN
Sbjct: 241 KKLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNN 300
Query: 301 DLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKS 360
DLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKS
Sbjct: 301 DLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKS 360
Query: 361 PSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERG 420
PSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERG
Sbjct: 361 PSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERG 420
Query: 421 IRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKR 480
IRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKR
Sbjct: 421 IRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKR 480
Query: 481 KKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQE 540
KKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQE
Sbjct: 481 KKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQE 540
Query: 541 LRKYKENEKDTEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQI 600
LRKYKENEKDTEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQI
Sbjct: 541 LRKYKENEKDTEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQI 600
Query: 601 LQKDQEIKDLKQKIAEVMAVMPSITYSAATSPLSPVSPHYSSKFVETSPSGLDPNASVYQ 660
LQKDQEIKDLKQKIAEVMAVMPSITYSAATSPLSPVSPHYSSKFVETSPSGLDPNASVYQ
Sbjct: 601 LQKDQEIKDLKQKIAEVMAVMPSITYSAATSPLSPVSPHYSSKFVETSPSGLDPNASVYQ 660
Query: 661 PLKK 664
PLKK
Sbjct: 661 PLKK 664
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 72.4 bits (176), Expect = 1e-12
Identities = 105/463 (22%), Positives = 185/463 (39%), Gaps = 35/463 (7%)
Query: 189 ENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKK-LSTTL 247
+N+ +Q LQ+ L Q+ L+ E E ++ L + ++ +N I N LS L
Sbjct: 429 DNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKL 488
Query: 248 PEIE--YREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHIN--SKRLNNDLV 303
E + Y E KE K+ LG+ + + S E+ E IN + L N L
Sbjct: 489 KETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNY-SHFHELRVTEEEINVLKQDLQNALE 547
Query: 304 GSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPST 363
S N KE K + G V P S S +N K+K
Sbjct: 548 ESERN--KEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEK-- 603
Query: 364 HKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRS 423
+++ E + K + + +K +A ++ EL Q+S LS + ++
Sbjct: 604 YQEAQEEIMKLKDTLKSQMTQEASDEAEDMK---EAMNRMIDELNKQVSELSQLYKEAQA 660
Query: 424 EMGQLRQENEL---LQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKR 480
E+ R+ L +H A K N+S+ + + A E +S K L E +
Sbjct: 661 ELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAE-DALSEMKSQYSKVLNELTQL 719
Query: 481 KKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQE 540
K+L +A +V+ + TLR +E+E + L + KE ++ +LE ++ E
Sbjct: 720 KQLVDAQKENSVSIT--EHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLE 777
Query: 541 LR-----------KYKENEKDTEVLMSAL-SAMQDKTQHLENSLSAETRIKLDLFSALGD 588
+ Y++ + E +S L S +++ + E S +I+ S +
Sbjct: 778 EKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIR----SEVSQ 833
Query: 589 AKRQLEIAQGQILQKDQEIKDLKQKIAEVMAVMPSITYSAATS 631
KR+ E Q + K+QE+ +L QK + + + A +S
Sbjct: 834 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESS 876
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 72.4 bits (176), Expect = 1e-12
Identities = 105/463 (22%), Positives = 185/463 (39%), Gaps = 35/463 (7%)
Query: 189 ENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKK-LSTTL 247
+N+ +Q LQ+ L Q+ L+ E E ++ L + ++ +N I N LS L
Sbjct: 418 DNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKL 477
Query: 248 PEIE--YREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHIN--SKRLNNDLV 303
E + Y E KE K+ LG+ + + S E+ E IN + L N L
Sbjct: 478 KETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNY-SHFHELRVTEEEINVLKQDLQNALE 536
Query: 304 GSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPST 363
S N KE K + G V P S S +N K+K
Sbjct: 537 ESERN--KEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEK-- 592
Query: 364 HKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRS 423
+++ E + K + + +K +A ++ EL Q+S LS + ++
Sbjct: 593 YQEAQEEIMKLKDTLKSQMTQEASDEAEDMK---EAMNRMIDELNKQVSELSQLYKEAQA 649
Query: 424 EMGQLRQENEL---LQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKR 480
E+ R+ L +H A K N+S+ + + A E +S K L E +
Sbjct: 650 ELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAE-DALSEMKSQYSKVLNELTQL 708
Query: 481 KKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQE 540
K+L +A +V+ + TLR +E+E + L + KE ++ +LE ++ E
Sbjct: 709 KQLVDAQKENSVSIT--EHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLE 766
Query: 541 LR-----------KYKENEKDTEVLMSAL-SAMQDKTQHLENSLSAETRIKLDLFSALGD 588
+ Y++ + E +S L S +++ + E S +I+ S +
Sbjct: 767 EKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIR----SEVSQ 822
Query: 589 AKRQLEIAQGQILQKDQEIKDLKQKIAEVMAVMPSITYSAATS 631
KR+ E Q + K+QE+ +L QK + + + A +S
Sbjct: 823 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESS 865
>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
Length = 951
Score = 72.4 bits (176), Expect = 1e-12
Identities = 105/463 (22%), Positives = 185/463 (39%), Gaps = 35/463 (7%)
Query: 189 ENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKK-LSTTL 247
+N+ +Q LQ+ L Q+ L+ E E ++ L + ++ +N I N LS L
Sbjct: 397 DNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKL 456
Query: 248 PEIE--YREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHIN--SKRLNNDLV 303
E + Y E KE K+ LG+ + + S E+ E IN + L N L
Sbjct: 457 KETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNY-SHFHELRVTEEEINVLKQDLQNALE 515
Query: 304 GSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPST 363
S N KE K + G V P S S +N K+K
Sbjct: 516 ESERN--KEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEK-- 571
Query: 364 HKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRS 423
+++ E + K + + +K +A ++ EL Q+S LS + ++
Sbjct: 572 YQEAQEEIMKLKDTLKSQMTQEASDEAEDMK---EAMNRMIDELNKQVSELSQLYKEAQA 628
Query: 424 EMGQLRQENEL---LQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKR 480
E+ R+ L +H A K N+S+ + + A E +S K L E +
Sbjct: 629 ELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAE-DALSEMKSQYSKVLNELTQL 687
Query: 481 KKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQE 540
K+L +A +V+ + TLR +E+E + L + KE ++ +LE ++ E
Sbjct: 688 KQLVDAQKENSVSIT--EHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLE 745
Query: 541 LR-----------KYKENEKDTEVLMSAL-SAMQDKTQHLENSLSAETRIKLDLFSALGD 588
+ Y++ + E +S L S +++ + E S +I+ S +
Sbjct: 746 EKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIR----SEVSQ 801
Query: 589 AKRQLEIAQGQILQKDQEIKDLKQKIAEVMAVMPSITYSAATS 631
KR+ E Q + K+QE+ +L QK + + + A +S
Sbjct: 802 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESS 844
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 72.4 bits (176), Expect = 1e-12
Identities = 105/463 (22%), Positives = 185/463 (39%), Gaps = 35/463 (7%)
Query: 189 ENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKK-LSTTL 247
+N+ +Q LQ+ L Q+ L+ E E ++ L + ++ +N I N LS L
Sbjct: 426 DNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKL 485
Query: 248 PEIE--YREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHIN--SKRLNNDLV 303
E + Y E KE K+ LG+ + + S E+ E IN + L N L
Sbjct: 486 KETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNY-SHFHELRVTEEEINVLKQDLQNALE 544
Query: 304 GSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPST 363
S N KE K + G V P S S +N K+K
Sbjct: 545 ESERN--KEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEK-- 600
Query: 364 HKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRS 423
+++ E + K + + +K +A ++ EL Q+S LS + ++
Sbjct: 601 YQEAQEEIMKLKDTLKSQMTQEASDEAEDMK---EAMNRMIDELNKQVSELSQLYKEAQA 657
Query: 424 EMGQLRQENEL---LQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKR 480
E+ R+ L +H A K N+S+ + + A E +S K L E +
Sbjct: 658 ELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAE-DALSEMKSQYSKVLNELTQL 716
Query: 481 KKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQE 540
K+L +A +V+ + TLR +E+E + L + KE ++ +LE ++ E
Sbjct: 717 KQLVDAQKENSVSIT--EHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLE 774
Query: 541 LR-----------KYKENEKDTEVLMSAL-SAMQDKTQHLENSLSAETRIKLDLFSALGD 588
+ Y++ + E +S L S +++ + E S +I+ S +
Sbjct: 775 EKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIR----SEVSQ 830
Query: 589 AKRQLEIAQGQILQKDQEIKDLKQKIAEVMAVMPSITYSAATS 631
KR+ E Q + K+QE+ +L QK + + + A +S
Sbjct: 831 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESS 873
>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 72.4 bits (176), Expect = 1e-12
Identities = 105/463 (22%), Positives = 185/463 (39%), Gaps = 35/463 (7%)
Query: 189 ENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKK-LSTTL 247
+N+ +Q LQ+ L Q+ L+ E E ++ L + ++ +N I N LS L
Sbjct: 426 DNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKL 485
Query: 248 PEIE--YREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHIN--SKRLNNDLV 303
E + Y E KE K+ LG+ + + S E+ E IN + L N L
Sbjct: 486 KETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNY-SHFHELRVTEEEINVLKQDLQNALE 544
Query: 304 GSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPST 363
S N KE K + G V P S S +N K+K
Sbjct: 545 ESERN--KEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEK-- 600
Query: 364 HKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRS 423
+++ E + K + + +K +A ++ EL Q+S LS + ++
Sbjct: 601 YQEAQEEIMKLKDTLKSQMTQEASDEAEDMK---EAMNRMIDELNKQVSELSQLYKEAQA 657
Query: 424 EMGQLRQENEL---LQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKR 480
E+ R+ L +H A K N+S+ + + A E +S K L E +
Sbjct: 658 ELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAE-DALSEMKSQYSKVLNELTQL 716
Query: 481 KKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQE 540
K+L +A +V+ + TLR +E+E + L + KE ++ +LE ++ E
Sbjct: 717 KQLVDAQKENSVSIT--EHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLE 774
Query: 541 LR-----------KYKENEKDTEVLMSAL-SAMQDKTQHLENSLSAETRIKLDLFSALGD 588
+ Y++ + E +S L S +++ + E S +I+ S +
Sbjct: 775 EKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIR----SEVSQ 830
Query: 589 AKRQLEIAQGQILQKDQEIKDLKQKIAEVMAVMPSITYSAATS 631
KR+ E Q + K+QE+ +L QK + + + A +S
Sbjct: 831 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESS 873
>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 72.4 bits (176), Expect = 1e-12
Identities = 105/463 (22%), Positives = 185/463 (39%), Gaps = 35/463 (7%)
Query: 189 ENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKK-LSTTL 247
+N+ +Q LQ+ L Q+ L+ E E ++ L + ++ +N I N LS L
Sbjct: 426 DNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKL 485
Query: 248 PEIE--YREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHIN--SKRLNNDLV 303
E + Y E KE K+ LG+ + + S E+ E IN + L N L
Sbjct: 486 KETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNY-SHFHELRVTEEEINVLKQDLQNALE 544
Query: 304 GSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPST 363
S N KE K + G V P S S +N K+K
Sbjct: 545 ESERN--KEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEK-- 600
Query: 364 HKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRS 423
+++ E + K + + +K +A ++ EL Q+S LS + ++
Sbjct: 601 YQEAQEEIMKLKDTLKSQMTQEASDEAEDMK---EAMNRMIDELNKQVSELSQLYKEAQA 657
Query: 424 EMGQLRQENEL---LQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKR 480
E+ R+ L +H A K N+S+ + + A E +S K L E +
Sbjct: 658 ELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAE-DALSEMKSQYSKVLNELTQL 716
Query: 481 KKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQE 540
K+L +A +V+ + TLR +E+E + L + KE ++ +LE ++ E
Sbjct: 717 KQLVDAQKENSVSIT--EHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLE 774
Query: 541 LR-----------KYKENEKDTEVLMSAL-SAMQDKTQHLENSLSAETRIKLDLFSALGD 588
+ Y++ + E +S L S +++ + E S +I+ S +
Sbjct: 775 EKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIR----SEVSQ 830
Query: 589 AKRQLEIAQGQILQKDQEIKDLKQKIAEVMAVMPSITYSAATS 631
KR+ E Q + K+QE+ +L QK + + + A +S
Sbjct: 831 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESS 873
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 72.0 bits (175), Expect = 2e-12
Identities = 111/519 (21%), Positives = 220/519 (42%), Gaps = 97/519 (18%)
Query: 177 KMRLRKQKEVQKENEFYMQLLQQALPPEQQ-------MLQKQEKEAEEAAKGLPDM-DSS 228
K ++ +++ ENE LQQ PP ++ + + +K++EE + ++ D
Sbjct: 784 KSKICSERKRVNENE-----LQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIEDIR 838
Query: 229 ILIHHNGGIPA-------------------NKKLSTTLPEIEYREKGKEKDKDAKKHNLG 269
+L +N G+ A NK++ E+ EK K+ K
Sbjct: 839 VLQENNEGLRAFLLTIENELKNEKEEKAELNKQIVHFQQELSLSEK---KNLTLSKEVQQ 895
Query: 270 INNNNILQPVDSKIQEIEYMENHINSKRLNNDLVGSTENLLK------------EDSCTA 317
I +N + + +Q+ + E +L+N++ +T ++ ++ T
Sbjct: 896 IQSNYDIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTL 955
Query: 318 SSKNYKNASGVVNSSPRSHSATNGSIPSSS----------SKNEKKQKCT--SKSPSTHK 365
S + + ++N S+ + ++P++ SK K+ + ++ S H
Sbjct: 956 DSVSQISNIDLLNLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHS 1015
Query: 366 DL---MENC--IPNNQLSKPDALVRLEQDIKKLKADLQA-----SRQVEQELRSQISSLS 415
+ E C I K + LEQ I+KL+A+++ +R E+E ++Q L
Sbjct: 1016 SIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLK 1075
Query: 416 STERGIRSEMGQLRQENELLQNKLHNAVQMKQ---KDKQNISQLEKKLKAEQEARSFVEK 472
E I+ +L+++N L ++ + V+ K+ + Q ++ + K+K E + +E
Sbjct: 1076 EKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIK---ELETILET 1132
Query: 473 QLMEEKKRKKLEEATAARAVAFAAASRG--ECTETLRNRIRELEAEGKKLTMDMKVKE-- 528
Q +E KLE+ + R E E L++ ++ T D+ VKE
Sbjct: 1133 QKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKN--------TKDLNVKELK 1184
Query: 529 --DQIRELELKVQELR--------KYKENEKDTEVLMSALSAMQDKTQHLENSLSAETRI 578
++I +L +Q+++ + + N ++TE L LSA +TQ+L+ L +
Sbjct: 1185 LKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEED 1244
Query: 579 KLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAEV 617
DL L DAK+Q++ Q ++ E K L+ KI E+
Sbjct: 1245 YADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINEL 1283
Score = 57.0 bits (136), Expect = 5e-08
Identities = 87/476 (18%), Positives = 203/476 (42%), Gaps = 89/476 (18%)
Query: 181 RKQKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPAN 240
+ Q ++ KE E +Q L++ L + L Q + E + L ++ + +
Sbjct: 1068 KNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYK----AKI 1123
Query: 241 KKLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEI-EYMENHI-NSKRL 298
K+L T L + E AK + +I+ ++ ++E E++++ + N+K L
Sbjct: 1124 KELETIL-----ETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDL 1178
Query: 299 NNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEK-KQKCT 357
N + L ++ T + N ++ ++ ++ + EK K++ +
Sbjct: 1179 N------VKELKLKEEITQLTNNLQDMKHLLQLKEEEEE-------TNRQETEKLKEELS 1225
Query: 358 SKSPSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSST 417
+ S T + LKADLQ + +L+ +++
Sbjct: 1226 ASSART---------------------------QNLKADLQRKEEDYADLKEKLTDAKKQ 1258
Query: 418 ERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEE 477
+ ++ E+ +R E++LL+ K++ ++++K Q +L+ K + Q+ + + Q +EE
Sbjct: 1259 IKQVQKEVSVMRDEDKLLRIKIN---ELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEE 1315
Query: 478 K----KRKKLEEATAARAVAFAAASRGECTETLRNRIRELEA---EGKKLTMDMKVKEDQ 530
+R + + + + E +T + + LEA E ++L +++ +++
Sbjct: 1316 AIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEK 1375
Query: 531 IRELELKVQELRKYKENEKDTEVLMSALSAMQDKTQHLENSLSAETR----IKLDLFSAL 586
+LE K + R KE+E +T+VL L+ +QD+ Q E +A+ + K+ L +
Sbjct: 1376 CNDLETKNNQ-RSNKEHENNTDVL-GKLTNLQDELQESEQKYNADRKKWLEEKMMLITQA 1433
Query: 587 GDA---------------------KRQLEIAQGQILQKDQEIKDLKQKIAEVMAVM 621
+A + ++EI Q+ +KD +++ +++ +++A +
Sbjct: 1434 KEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQLVAAL 1489
Score = 30.0 bits (66), Expect = 7.1
Identities = 41/178 (23%), Positives = 81/178 (45%), Gaps = 32/178 (17%)
Query: 404 EQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAE 463
+++L ++ + T+ + +++ + L +NK + + K+K I L+KKL E
Sbjct: 532 DEDLVEELENAEETQN-VETKLLDEDLDKTLEENKAFISHEEKRKLLDLIEDLKKKLINE 590
Query: 464 QEARSFVEKQLMEE---------------------KKRKKLEEATAARAVAFAAASRGEC 502
++ + +E ++ EE ++R+ LEE A R +A G+C
Sbjct: 591 KKEKLTLEFKIREEVTQEFTQYWAQREADFKETLLQEREILEE-NAERRLAIFKDLVGKC 649
Query: 503 --TETLRNRIRELEAEGKKLTMDMKVKEDQIR-ELE------LKVQELRKYKENEKDT 551
E I + E ++ T +++K +QI+ EL +K +E K +ENE D+
Sbjct: 650 DTREEAAKDICATKVETEEATACLELKFNQIKAELAKTKGELIKTKEELKKRENESDS 707
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 71.6 bits (174), Expect = 2e-12
Identities = 103/472 (21%), Positives = 196/472 (41%), Gaps = 77/472 (16%)
Query: 188 KENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKKLSTTL 247
K+ +F LQ + EQ + + +K+ +E + +++ I K+ S
Sbjct: 1082 KKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYA 1141
Query: 248 PEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNNDLVGSTE 307
E+E + E+ + +N K +E E++ +L DL +T
Sbjct: 1142 RELEELSERLEEAGGVTSTQIELN----------KKREAEFL-------KLRRDLEEAT- 1183
Query: 308 NLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPSTHKDL 367
L+ ++ A+ + K+A V + + K+E K + S S
Sbjct: 1184 --LQHEAMVAALRK-KHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSS----- 1235
Query: 368 MENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQ 427
ME+ +SK A LE+ + L+ L +R +E++ +S L++ + +++E G+
Sbjct: 1236 MES------VSKSKA--NLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGE 1287
Query: 428 LRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARS--------------FVEKQ 473
L ++ E ++ + + KQ Q +L+++L+ E +A++ + +Q
Sbjct: 1288 LSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQ 1347
Query: 474 LMEEKKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRE 533
EE++ K + ++A + A R + R ELE KKL ++ E+Q+
Sbjct: 1348 YEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEA 1407
Query: 534 LELKVQELRKYKEN-EKDTEVLM------SALSAMQDKTQ-------------------H 567
+ K L K K+ + + E LM ++L+A DK Q
Sbjct: 1408 VNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAE 1467
Query: 568 LENSLSAETRIKLDLF---SALGDAKRQLEIAQGQILQKDQEIKDLKQKIAE 616
LE SL + +LF +A +A QLE + + +QEI DL ++IAE
Sbjct: 1468 LEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAE 1519
Score = 66.6 bits (161), Expect = 7e-11
Identities = 112/511 (21%), Positives = 203/511 (39%), Gaps = 71/511 (13%)
Query: 171 KSYVSYKMRLRKQKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSIL 230
K + K +K K+ ++E + L++ L Q + + + ++ L D +
Sbjct: 848 KEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERC- 906
Query: 231 IHHNGGIPANKKLSTTLPEIEYREKGKEK---DKDAKKHNLGINNNNILQPVDS---KIQ 284
+ I A +L + E+ R + +E+ + AKK L + + + +D +
Sbjct: 907 ---DQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 963
Query: 285 EIEYMENHINSKRLNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIP 344
++E E H ++ N TE L D A K A +H +
Sbjct: 964 KVE-KEKHATENKVKN----LTEELSGLDETIAKLTREKKAL------QEAHQQALDDLQ 1012
Query: 345 SSSSKNEKKQKCTSKSPSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVE 404
+ K K SK +DL + +L V LE++ +KL+ DL+ +++
Sbjct: 1013 AEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLR-----VDLERNKRKLEGDLKLAQESI 1067
Query: 405 QELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQ-NISQLEKKLKAE 463
+L + L + E QL+ + E Q L Q K K+ Q I +LE++++AE
Sbjct: 1068 LDLENDKQQLDERLKKKDFEYCQLQSKVEDEQT-LGLQFQKKIKELQARIEELEEEIEAE 1126
Query: 464 QEARSFVEKQL-------------MEE--------------------KKRKKLEEATAAR 490
+ R+ EKQ +EE K R+ LEEAT
Sbjct: 1127 RATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQH 1186
Query: 491 AVAFAAASR--GECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKEN- 547
AA + + L +I L+ +KL + + +I +L ++ + K K N
Sbjct: 1187 EAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANL 1246
Query: 548 EKDTEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKD--- 604
EK L LS + K + ++ SLS T K L + G+ RQLE + + Q
Sbjct: 1247 EKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSK 1306
Query: 605 ----QEIKDLKQKIAEVMAVMPSITYSAATS 631
Q+ ++LK+++ E ++ ++ +S
Sbjct: 1307 QAFTQQTEELKRQLEEENKAKNALAHALQSS 1337
Score = 56.6 bits (135), Expect = 7e-08
Identities = 98/424 (23%), Positives = 171/424 (40%), Gaps = 40/424 (9%)
Query: 205 QQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPAN-KKLSTTLPEIEYREKGKEKDKDA 263
Q++ QK EKE E + D+ SS+ AN +K+ TL + +GK ++
Sbjct: 1212 QRVKQKLEKEKSEFKLEIDDLSSSM--ESVSKSKANLEKICRTLEDQLSEARGKNEEIQR 1269
Query: 264 KKHNLGINNNNILQPVDSKIQEIEYMENHINS-KRLNNDLVGSTENLLKEDSCTASSKNY 322
L + + +++E E+ ++ R TE L ++ +KN
Sbjct: 1270 SLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNA 1329
Query: 323 KNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPSTHKDLMENCIPNNQLSKPDA 382
+ + SS + Q+ SK+ S + DA
Sbjct: 1330 --LAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKY-------ETDA 1380
Query: 383 LVR---LEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKL 439
+ R LE+ KKL LQ S + + + ++ +SL T++ ++ E+ L + E N L
Sbjct: 1381 IQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERA-NSL 1439
Query: 440 HNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASR 499
A+ KQ++ + E K K E E+++ +E L E + +T + A
Sbjct: 1440 AAALDKKQRNFDKVLA-EWKTKCE-ESQAELEASLKESRSL-----STELFKLKNAYEEA 1492
Query: 500 GECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKENEKDTEVLMSALS 559
+ ET++ + LE E LT + I ELE + RK E EK L
Sbjct: 1493 LDQLETVKRENKNLEQEIADLTEQIAENGKTIHELE----KSRKQIELEKADIQL----- 1543
Query: 560 AMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAEVMA 619
A+++ LE+ + RI+L+L + R+ I +KD+EI+ LK+ +
Sbjct: 1544 ALEEAEAALEHEEAKILRIQLELTQVKSEIDRK-------IAEKDEEIEQLKRNYQRTVE 1596
Query: 620 VMPS 623
M S
Sbjct: 1597 TMQS 1600
Score = 51.2 bits (121), Expect = 3e-06
Identities = 52/247 (21%), Positives = 102/247 (41%), Gaps = 34/247 (13%)
Query: 397 LQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMK-------QKD 449
L S + E+E+ + T + E+ + + + L+ KL VQ K Q +
Sbjct: 840 LLKSAETEKEMATMKEEFQKT----KDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAE 895
Query: 450 KQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRNR 509
+N+ E++ +A+ +E ++ E +R + EE A A EC+E L+
Sbjct: 896 SENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE-LKKD 954
Query: 510 IRELEAEGKKLTMDMKVKEDQIREL----------------------ELKVQELRKYKEN 547
I +LE K+ + E++++ L E Q L +
Sbjct: 955 IDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAE 1014
Query: 548 EKDTEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEI 607
E L S ++ + + LE+SL E ++++DL + L++AQ IL + +
Sbjct: 1015 EDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDK 1074
Query: 608 KDLKQKI 614
+ L +++
Sbjct: 1075 QQLDERL 1081
Score = 47.8 bits (112), Expect = 3e-05
Identities = 90/495 (18%), Positives = 203/495 (41%), Gaps = 74/495 (14%)
Query: 180 LRKQKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPA 239
L+ QK++ KE + ++ L++ + E+ K EK+ + A+ L ++ + GG+ +
Sbjct: 1103 LQFQKKI-KELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERL--EEAGGVTS 1159
Query: 240 NKKLSTTLPEIEYREKGKEKDKDAKKHNLGI-----NNNNILQPVDSKIQEIEYMENHIN 294
+ E E+ + ++ ++ +H + + + + + +I ++ ++ +
Sbjct: 1160 TQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLE 1219
Query: 295 SKRLNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQ 354
++ +E L+ D ++S ++ + + R+ + + KNE+ Q
Sbjct: 1220 KEK--------SEFKLEIDDLSSSMESVSKSKANLEKICRT---LEDQLSEARGKNEEIQ 1268
Query: 355 KCTSKSPSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSL 414
+ S+ + L +LS+ L E + +L QA Q +EL+ Q+
Sbjct: 1269 RSLSELTTQKSRLQTEA---GELSRQ--LEEKESIVSQLSRSKQAFTQQTEELKRQLEEE 1323
Query: 415 SSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKL---KAEQEARSFVE 471
+ + + + R + +LL+ + + K + ++ +S+ ++ + + E +
Sbjct: 1324 NKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQR 1383
Query: 472 KQLMEEKKRK---KLEEATA-ARAVAFAAASRGECTETLRNRIRELEAEGK--------- 518
+ +EE K+K +L+++ AV AS + + L+ + +L + +
Sbjct: 1384 TEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAAL 1443
Query: 519 --------KLTMDMKVK-EDQIRELELKVQELRKY---------------------KENE 548
K+ + K K E+ ELE ++E R K
Sbjct: 1444 DKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKREN 1503
Query: 549 KDTEVLMSALS---AMQDKTQH-LENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKD 604
K+ E ++ L+ A KT H LE S K D+ AL +A+ LE + +IL+
Sbjct: 1504 KNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQ 1563
Query: 605 QEIKDLKQKIAEVMA 619
E+ +K +I +A
Sbjct: 1564 LELTQVKSEIDRKIA 1578
Score = 47.0 bits (110), Expect = 6e-05
Identities = 52/242 (21%), Positives = 111/242 (45%), Gaps = 21/242 (8%)
Query: 394 KADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNI 453
+A+L+AS + + L +++ L + ++ +++EN+ L+ ++ + + ++ + I
Sbjct: 1465 QAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTI 1524
Query: 454 SQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAAR----------AVAFAAASRGECT 503
+LEK K + ++ ++ L E + + EEA R + A + E
Sbjct: 1525 HELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEI 1584
Query: 504 ETL-RNRIRELEAEGKKLTMDMKVKEDQIR-----ELELKVQELRKYKENEKDTEV---L 554
E L RN R +E L +++ + + IR E +L E++ N + E L
Sbjct: 1585 EQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHL 1644
Query: 555 MSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKI 614
S ++D HL+++L + +K L A+ + + L A+ + L+ E + +K+
Sbjct: 1645 RSVQGQLKDTQLHLDDALRGQEDLKEQL--AIVERRANLLQAEVEELRATLEQTERARKL 1702
Query: 615 AE 616
AE
Sbjct: 1703 AE 1704
Score = 43.1 bits (100), Expect = 8e-04
Identities = 56/265 (21%), Positives = 122/265 (46%), Gaps = 34/265 (12%)
Query: 364 HKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQ-ELRSQISSLSSTERGIR 422
H ++ + + QL DAL R ++D+K+ A ++ + Q E+ ++L TER +
Sbjct: 1643 HLRSVQGQLKDTQLHLDDAL-RGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARK 1701
Query: 423 SEMGQLRQENE---LLQNKLHNAVQMKQKDKQNISQLEKKLK--------AEQEARSFVE 471
+L NE LL + + + K+K + ++ QL+ +++ AE++A+ +
Sbjct: 1702 LAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAIT 1761
Query: 472 KQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQI 531
M ++ KK ++ +A + + + + L++R+ E E + +K + QI
Sbjct: 1762 DAAMMAEELKKEQDTSA--HLERMKKNLEQTVKDLQHRLDEAE------QLALKGGKKQI 1813
Query: 532 RELELKVQELRKYKENEKDTEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKR 591
++LE +++EL E E+ + T+ ++ E R+K + + D K
Sbjct: 1814 QKLETRIRELEFELEGEQ------------KKNTESVKGLRKYERRVKELTYQSEEDRKN 1861
Query: 592 QLEIAQGQILQKDQEIKDLKQKIAE 616
L + Q + + ++K K++ E
Sbjct: 1862 VLRL-QDLVDKLQVKVKSYKRQAEE 1885
Score = 34.3 bits (77), Expect = 0.38
Identities = 45/230 (19%), Positives = 99/230 (43%), Gaps = 19/230 (8%)
Query: 376 QLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELL 435
+L K D + LE+ L+ + +++ EL S + E+ QL++ +
Sbjct: 1535 ELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRT 1594
Query: 436 QNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFA 495
+ +A+ + + + +L+KK++ + +E QL ++ AA +
Sbjct: 1595 VETMQSALDAEVRSRNEAIRLKKKMEGDLNE---IEIQLSHANRQ-------AAETLKHL 1644
Query: 496 AASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELR-KYKENEKDTEVL 554
+ +G+ +T + L + + L + + E + L+ +V+ELR ++ E+ ++
Sbjct: 1645 RSVQGQLKDTQLHLDDALRGQ-EDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLA 1703
Query: 555 MSALSAMQDKTQ--HLENSLSAETRIKLD-----LFSALGDAKRQLEIAQ 597
L ++ Q H +N+ T+ KL+ L S + DA R A+
Sbjct: 1704 EQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAE 1753
Score = 31.2 bits (69), Expect = 3.2
Identities = 37/162 (22%), Positives = 69/162 (42%), Gaps = 24/162 (14%)
Query: 181 RKQKEVQKENEFYMQLLQQALPPEQQM---LQKQEKEAEEAAKGLPD-MDSSILIHHNGG 236
R +E K+ ++ + L EQ L++ +K E+ K L +D + + GG
Sbjct: 1750 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGG 1809
Query: 237 IPANKKLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYM--ENHIN 294
+KL T + E+E+ +G++ KK+ + L+ + +++E+ Y E+ N
Sbjct: 1810 KKQIQKLETRIRELEFELEGEQ-----KKNTESVKG---LRKYERRVKELTYQSEEDRKN 1861
Query: 295 SKRLNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSH 336
RL DLV D K+YK + + +H
Sbjct: 1862 VLRL-QDLV---------DKLQVKVKSYKRQAEEADEQANAH 1893
Score = 30.0 bits (66), Expect = 7.1
Identities = 60/308 (19%), Positives = 122/308 (39%), Gaps = 41/308 (13%)
Query: 205 QQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKKLSTTLPEIEYREKGKEKDKDAK 264
Q L+ + ++A +G D+ + I ++ + E+E E+ + A+
Sbjct: 1648 QGQLKDTQLHLDDALRGQEDLKEQLAI-------VERRANLLQAEVEELRATLEQTERAR 1700
Query: 265 KHNLGINNNNILQPVDSKIQEIEYMENHI--NSKRLNNDLVGSTENLLKEDSCTASSKNY 322
K + +L + ++Q + + K+L DL+ ++ +++ S A +
Sbjct: 1701 K----LAEQELLDS-NERVQLLHTQNTSLIHTKKKLETDLM-QLQSEVEDASRDARNAEE 1754
Query: 323 KNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPSTHKDLMENCIPNNQLSKPDA 382
K + +++ + S+ + KK T KDL QL+
Sbjct: 1755 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNL-----EQTVKDLQHRLDEAEQLALKGG 1809
Query: 383 ---LVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQE--NELLQN 437
+ +LE I++L+ +L+ ++ E + L ER ++ Q ++ N L
Sbjct: 1810 KKQIQKLETRIRELEFELEGEQKKNTE---SVKGLRKYERRVKELTYQSEEDRKNVLRLQ 1866
Query: 438 KLHNAVQMKQK---------DKQNISQLEKKLKAEQEARSFVEKQLMEE----KKRKKLE 484
L + +Q+K K D+Q + L K KA+ E E+ + E K R K
Sbjct: 1867 DLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTR 1926
Query: 485 EATAARAV 492
+ T++R V
Sbjct: 1927 DFTSSRMV 1934
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 71.2 bits (173), Expect = 3e-12
Identities = 94/469 (20%), Positives = 200/469 (42%), Gaps = 59/469 (12%)
Query: 171 KSYVSYKMRLRKQKEV-QKENEFYMQLLQQA--LPPEQQMLQKQEKEAEEAAKGLPDMDS 227
K S + +L+ +E+ Q+E + L + L E+ LQ+Q++E EEA K L +
Sbjct: 1308 KDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNL---EK 1364
Query: 228 SILIHHNGGIPANKKLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIE 287
+L + KK+ L IE E+ K+K +++ E
Sbjct: 1365 QVLALQSQLADTKKKVDDDLGTIESLEEAKKK----------------------LLKDAE 1402
Query: 288 YMENHINSKRLNNDLVGSTENLLKE--DSCTASSKNYKNASGVVNSSPRSHSATNGSIPS 345
+ + K L D + T+N L++ D T + + + + + S
Sbjct: 1403 ALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKS 1462
Query: 346 SSSKNEKKQKCTSKSPSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQ 405
S++ +++ +++ + K+ + +A E+ K+L+AD++ +
Sbjct: 1463 ISAR-YAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKD 1521
Query: 406 ELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNI----SQLEKKLK 461
++ + L ++R + ++ ++R + E L+++L K + + N+ +Q E+ L+
Sbjct: 1522 DVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQ 1581
Query: 462 AEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGK--- 518
E ++ L+++ + + E + A A AS+ + L++ ++EA K
Sbjct: 1582 TRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARD 1641
Query: 519 -------KLTMDMKVKEDQIRELELKVQEL-RKYKENEKDTEVLMSALSAMQDK------ 564
KL MK + ++ E E+ + KE+EK + L + + +Q++
Sbjct: 1642 EVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSER 1701
Query: 565 -TQHLE---NSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKD 609
+H E + L+ E SAL D KR+LE +I Q ++E+++
Sbjct: 1702 ARRHAEQERDELADEITNSASGKSALLDEKRRLE---ARIAQLEEELEE 1747
Score = 55.5 bits (132), Expect = 2e-07
Identities = 56/273 (20%), Positives = 121/273 (44%), Gaps = 28/273 (10%)
Query: 364 HKDLME--NCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGI 421
H+ L+E N + ++ + E+ +L A Q ++ +L S++ + +
Sbjct: 882 HQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQIL 941
Query: 422 RSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLK---------AEQEARSFVEK 472
++E +++ + L+ +L +QK + E K+K +Q ++ EK
Sbjct: 942 QNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEK 1001
Query: 473 QLMEEK----KRKKLEEATAARAVAFAAASRGECTETLRNRIR-------ELEAEGKKLT 521
+LME++ + EE A+ +A + L R++ ELE +KL
Sbjct: 1002 KLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLD 1061
Query: 522 MDMKVKEDQIRELELKVQELRKYKENEKDTEVLMSALSAMQDKTQHLENSLSAETRIKLD 581
+ +DQI EL+ ++ EL+ + K E L AL+ D+T H N+L ++ +
Sbjct: 1062 GETTDLQDQIAELQAQIDELK--LQLAKKEEELQGALARGDDETLHKNNAL----KVVRE 1115
Query: 582 LFSALGDAKRQLEIAQGQILQKDQEIKDLKQKI 614
L + + + + E + + +++ +DL +++
Sbjct: 1116 LQAQIAELQEDFESEKASRNKAEKQKRDLSEEL 1148
Score = 50.1 bits (118), Expect = 7e-06
Identities = 51/252 (20%), Positives = 114/252 (45%), Gaps = 33/252 (13%)
Query: 378 SKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERG----------IRSEMGQ 427
+K + L+++++ K++ +L+ + Q+L + + L+ + +R+ +
Sbjct: 856 AKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAA 915
Query: 428 LRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEE---KKRKKLE 484
+QE E + + L + V+ +++ Q + +KK++A + +E+QL EE +++ +LE
Sbjct: 916 KKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQD---LEEQLDEEEGARQKLQLE 972
Query: 485 EATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKY 544
+ TA + + + I LE + K + K+ ED+I E ++
Sbjct: 973 KVTAEAKI-----------KKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQL------ 1015
Query: 545 KENEKDTEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKD 604
E E+ + L + + LE L E + + +L A + Q QI +
Sbjct: 1016 AEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQ 1075
Query: 605 QEIKDLKQKIAE 616
+I +LK ++A+
Sbjct: 1076 AQIDELKLQLAK 1087
Score = 48.5 bits (114), Expect = 2e-05
Identities = 76/464 (16%), Positives = 182/464 (39%), Gaps = 33/464 (7%)
Query: 179 RLRKQKEVQKENEFYMQLLQ----------QALPPEQQMLQKQEKEAEEAAKGLPDMDSS 228
RL+K+++ ++E E + L L + L+ Q + EE +G
Sbjct: 1042 RLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDD 1101
Query: 229 ILIHHNGGIPANKKLSTTLPEIEY---REKGKEKDKDAKKHNLGINNNNILQPVDSKIQE 285
+H N + ++L + E++ EK + +K +L + ++ + +
Sbjct: 1102 ETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTL-D 1160
Query: 286 IEYMENHINSKRLNN--DLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSI 343
+ + +KR +L + E K ++A+ + S + A
Sbjct: 1161 TTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKR--F 1218
Query: 344 PSSSSKNEKKQKCTSKSPSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQV 403
++ KN++ + +K + +++ ++ + +L+ +++L A + ++
Sbjct: 1219 KANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRK----KLDAQVQELHAKVSEGDRL 1274
Query: 404 EQELRSQISSLSSTERGIRSEMGQLRQEN-------ELLQNKLHNAVQMKQKDKQNISQL 456
EL + S L + + + + + ++ L+++L + ++ Q++ + L
Sbjct: 1275 RVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNL 1334
Query: 457 EKKLKA-EQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEA 515
+++ E+E S E+Q EE+ RK LE+ A A + + I LE
Sbjct: 1335 SSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKK--VDDDLGTIESLEE 1392
Query: 516 EGKKLTMDMKVKEDQIRELELKVQELRKYKEN-EKDTEVLMSALSAMQDKTQHLENSLSA 574
KKL D + ++ E L +L K K +++ + L L + +LE
Sbjct: 1393 AKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKK 1452
Query: 575 ETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAEVM 618
++ + S + + A+ + +K+ + L + + E +
Sbjct: 1453 FDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEAL 1496
Score = 43.9 bits (102), Expect = 5e-04
Identities = 49/174 (28%), Positives = 78/174 (44%), Gaps = 29/174 (16%)
Query: 444 QMKQKDKQNISQLEKKLKAEQEARSFVEK--QLMEEKKRKKLEEATAARAVAFAAASRGE 501
+++ KD++ + EK+ K E E K QL+EEK L E A FA A
Sbjct: 853 ELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEK--NILAEQLQAETELFAEA---- 906
Query: 502 CTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKENEKDTEVLMSALSAM 561
E +R R+ + E E+ + +LE +V+ E E+ ++L + M
Sbjct: 907 --EEMRARLAAKKQE----------LEEILHDLESRVE------EEEERNQILQNEKKKM 948
Query: 562 QDKTQHLENSLSAE--TRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQK 613
Q Q LE L E R KL L +AK + ++ + +L +DQ K +K+K
Sbjct: 949 QAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIK-KMEEEILLLEDQNSKFIKEK 1001
Score = 43.5 bits (101), Expect = 6e-04
Identities = 88/462 (19%), Positives = 196/462 (42%), Gaps = 75/462 (16%)
Query: 181 RKQKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPAN 240
R+++E+Q ++E +++ ++ E + L++ E++ ++ + + +IL + A
Sbjct: 849 RQEEELQAKDEELLKVKEKQTKVEGE-LEEMERKHQQLLE-----EKNILAEQ---LQAE 899
Query: 241 KKLSTTLPEIEYREKGKEKDKDAKKHNLGIN------NNNILQPVDSKIQEIEYMENHIN 294
+L E+ R K+++ + H+L N ILQ E + M+ HI
Sbjct: 900 TELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQ------NEKKKMQAHIQ 953
Query: 295 SKRLNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQ 354
D L+ + TA +K K ++ ++ I ++
Sbjct: 954 DLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKF----IKEKKLMEDRIA 1009
Query: 355 KCTSKSPSTHKDLMENCIPNNQLSKPDALVR-LEQDIKKLKADLQASRQVEQELRSQISS 413
+C+S+ + N K + ++ LE+ +KK + Q + +++L + +
Sbjct: 1010 ECSSQLAEEEEKAKNLAKIRN---KQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTD 1066
Query: 414 LSSTERGIRSEMG----QLRQENELLQNKL----------HNAVQMKQKDKQNISQLEKK 459
L +++++ QL ++ E LQ L +NA+++ ++ + I++L++
Sbjct: 1067 LQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQED 1126
Query: 460 LKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKK 519
++E+ +R+ EKQ KR EE A + + LR + + AE KK
Sbjct: 1127 FESEKASRNKAEKQ-----KRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKK 1181
Query: 520 -LTMDMKVKEDQIR-----------ELELKVQELRKYKEN--------EKDTEVLMSALS 559
L + K E QI+ EL ++++ +++K N E D + L +
Sbjct: 1182 ALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVK 1241
Query: 560 AMQD---KTQHLENSLSAETRIKLDLFSALGDAKR-QLEIAQ 597
+Q +++H L A+ + +L + + + R ++E+A+
Sbjct: 1242 VLQQVKAESEHKRKKLDAQVQ---ELHAKVSEGDRLRVELAE 1280
Score = 35.4 bits (80), Expect = 0.17
Identities = 57/259 (22%), Positives = 103/259 (39%), Gaps = 40/259 (15%)
Query: 385 RLEQDIKKLKADLQASRQVEQELRS--------QISSLS---STERGIRSEMGQLRQENE 433
RLE I +L+ +L+ Q EL + Q+ +L+ + ER + RQ+ E
Sbjct: 1733 RLEARIAQLEEELE-EEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLE 1791
Query: 434 LLQNKLHNAVQ-----MKQKDKQNISQLEKKL-----KAEQEARSFVEKQLMEEKKRKKL 483
+L +Q +K K K IS LE K+ + EQEA+ + + KKL
Sbjct: 1792 RQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKL 1851
Query: 484 EEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRK 543
+E + + + ++ + A K+L ++ E++ ++L+
Sbjct: 1852 KE------IFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQ- 1904
Query: 544 YKENEKDTEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQK 603
+E + TE A + + L+N L I FS+ +RQL + +
Sbjct: 1905 -RELDDATE----ANEGLSREVSTLKNRLRRGGPIS---FSSSRSGRRQLHLEGASLELS 1956
Query: 604 DQEIKDLKQKIAEVMAVMP 622
D D + K ++V P
Sbjct: 1957 DD---DTESKTSDVNETQP 1972
Score = 30.4 bits (67), Expect = 5.5
Identities = 23/90 (25%), Positives = 46/90 (51%), Gaps = 9/90 (10%)
Query: 530 QIRELELKVQELRKYKENEKDTEVLMSALSAMQDKTQHL---ENSLSAETRIKLDLFSAL 586
Q EL+ K +EL K KE + E L M+ K Q L +N L+ + + + +LF+
Sbjct: 850 QEEELQAKDEELLKVKEKQTKVE---GELEEMERKHQQLLEEKNILAEQLQAETELFAEA 906
Query: 587 GDAKRQLEIAQGQILQKDQEIKDLKQKIAE 616
+ + +L + ++ ++ + DL+ ++ E
Sbjct: 907 EEMRARLAAKKQEL---EEILHDLESRVEE 933
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 70.5 bits (171), Expect = 5e-12
Identities = 77/365 (21%), Positives = 163/365 (44%), Gaps = 38/365 (10%)
Query: 277 QPVDSKIQEIEYMENHINSKRLNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSH 336
Q V +QE++ +++ +N N + TENLLK++ ++Y N S
Sbjct: 281 QEVAVYVQELQKLKSSVNELTQKNQTL--TENLLKKE------QDYTKLEEKHNEESVSK 332
Query: 337 SATNGSIPSSSSKNEKKQKCTSKSPST----HKDLMENCIPNNQLSKPDALVRLEQDIKK 392
++ ++ Q S S ++ H +L E +L + L +E +
Sbjct: 333 KNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLK--EELSEVETKYQH 390
Query: 393 LKADLQASRQVEQE-------LRSQISSLSS----TERGIRSEMGQLRQENELLQNKLHN 441
LKA+ + +Q +E L+S+I+ L S TER + G+L+++ +L KL +
Sbjct: 391 LKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMD 450
Query: 442 AVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGE 501
Q + +S+LE++LK + + ++ QL + K++ + ++A A ++ +
Sbjct: 451 KEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQND 510
Query: 502 CTETLR------NRIRELEAEGKKLTMDMKVKEDQIRELELKVQ----ELRKYKENEKDT 551
+ LR +I+ LEA +K ++ + E + +L K+Q E + ++
Sbjct: 511 LEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKN 570
Query: 552 EVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLK 611
L ++ + T+ L+N + + + +L + + K L AQ ++L + + +L
Sbjct: 571 HTLQEQVTQL---TEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELN 627
Query: 612 QKIAE 616
++ E
Sbjct: 628 SQLNE 632
Score = 70.5 bits (171), Expect = 5e-12
Identities = 105/521 (20%), Positives = 197/521 (37%), Gaps = 86/521 (16%)
Query: 179 RLRKQKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIP 238
+L +KE+ +Q +AL +Q L KQE+E + + + I H
Sbjct: 773 QLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHE---E 829
Query: 239 ANKKLSTTLPEIEYREKGKE---------KDKDAKKHNLGINNNNILQPVDSKIQEIEYM 289
N ++ TT+ E++ + KE KDK +K + N+ + + + K + +
Sbjct: 830 LNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQK-GKAAIL 888
Query: 290 ENHINSKRLNNDLVGSTENLLKED-------------------SCTASSKNYKNASGVVN 330
+ K L + L EN LKE + + A +
Sbjct: 889 DLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLK 948
Query: 331 SSPRSHSATNGSIPSSSSKNEKKQKCTS------KSPSTHKDLMEN-------------- 370
+ + G+I +E+K+K K K +EN
Sbjct: 949 QNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELA 1008
Query: 371 -------CIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRS 423
+ NN + +L+ D +++L A+R Q+L+S LS + + S
Sbjct: 1009 AEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATR---QDLKSVEEKLSLAQEDLIS 1065
Query: 424 EMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQE---ARSFVEKQLMEEKKR 480
Q+ +N+L+Q ++Q + QL+++ KA Q+ +S EK+L+ EK +
Sbjct: 1066 NRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSK 1125
Query: 481 KKLEEATAARAVAFAAASRGECTETLRNRIRE---------------LEAEGK----KLT 521
E R E I+E LE +GK K
Sbjct: 1126 LAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAA 1185
Query: 522 MDMKVKEDQIRELELKVQELRKYKE-NEKDTEVLMSALSAMQDKTQHLENSLSAETRIKL 580
++ + + QI + ++K +E KE EK+ ++ +H EN +I
Sbjct: 1186 VEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITA 1245
Query: 581 DLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAEVMAVM 621
L LG K++ + +Q ++ + +++ DL+ +IA + A +
Sbjct: 1246 -LNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATV 1285
Score = 64.7 bits (156), Expect = 3e-10
Identities = 97/478 (20%), Positives = 202/478 (42%), Gaps = 55/478 (11%)
Query: 194 MQLLQQALPPEQQMLQKQEKEAEEAAKGLP--DMDSSILIHHNGGIPANKKLSTTLPEIE 251
+Q L+ L ++ + EKE E+ + + ++++L ++ T L E
Sbjct: 525 IQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKL 584
Query: 252 YREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSK---------RLNNDL 302
+ K H+ L+ ++ +E N +NS+ +L+ +
Sbjct: 585 KNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQI 644
Query: 303 VGSTENLLKEDSC-TASSKNYKN----ASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCT 357
TE LL ++ TA + +N A + + + + ++K + KQ+
Sbjct: 645 KAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHC 704
Query: 358 SKSPSTHKDLMENCIPNNQLSKP--DALVRLEQDIKKLKA-------DLQASRQVEQELR 408
S+ S K+ E + Q ++ + +LE D ++KA DLQ RQ+ +L
Sbjct: 705 SQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLE 764
Query: 409 SQISSLSST----ERGIRSEMGQLRQENELLQN---KLHNAVQMKQKDKQNISQLEKKLK 461
+ + LS + + S L++++E L++ KL + KQ KQ+ L ++ K
Sbjct: 765 LRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETK 824
Query: 462 AEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLT 521
+ E + + + E ++ K+E+ ++ + +++L+N E E E +K
Sbjct: 825 IQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGK 884
Query: 522 MDMKVKEDQIRELELKVQ-----------ELRKYKENEKD-TEVLMSALSAMQDKTQHLE 569
+ E +EL+ ++Q EL+K E EK+ + L L++MQ++ +
Sbjct: 885 AAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQ 944
Query: 570 NSLSAETRIKLDLFSALGD-------AKRQLEIAQGQ----ILQKDQEIKDLKQKIAE 616
N+L + + L + + K+Q+E QG+ +LQK + L+Q++ +
Sbjct: 945 NTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQ 1002
Score = 56.2 bits (134), Expect = 9e-08
Identities = 59/241 (24%), Positives = 114/241 (47%), Gaps = 30/241 (12%)
Query: 387 EQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMK 446
E++ +KLK + + +L+SQ +S +T +RSE+ + QE + VQ
Sbjct: 245 ERESEKLKDECK-------KLQSQYASSEATISQLRSELAKGPQEVAVY-------VQEL 290
Query: 447 QKDKQNISQLEKK--------LKAEQEARSFVEKQLMEEKKRKKLEEATAARAV-AFAAA 497
QK K ++++L +K LK EQ+ EK E +K ++ + +
Sbjct: 291 QKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQ 350
Query: 498 SRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELR-KYKENEKDTEVLMS 556
SR +ET +RI +E + T +K +++ E+E K Q L+ ++K+ ++ E
Sbjct: 351 SRLSASETSLHRIHVELSEKGEATQKLK---EELSEVETKYQHLKAEFKQLQQQREEKEQ 407
Query: 557 ALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAE 616
+Q + L + L R L A G K Q +++ +++ K+Q++ DL+ K++
Sbjct: 408 HGLQLQSEINQLHSKLLETER---QLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSR 464
Query: 617 V 617
+
Sbjct: 465 L 465
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 69.3 bits (168), Expect = 1e-11
Identities = 106/476 (22%), Positives = 190/476 (39%), Gaps = 79/476 (16%)
Query: 185 EVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKKLS 244
E K+ EF M LQ + EQ + + +K+ +E + +++ I A K+ S
Sbjct: 1082 EKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1141
Query: 245 TTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNNDLVG 304
E+E + E+ A + +N K +E E+ +++ DL
Sbjct: 1142 DLSRELEEISERLEEAGGATSAQIEMN----------KKREAEF-------QKMRRDL-- 1182
Query: 305 STENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPSTH 364
E + TA++ K+A V + I + +K +K S+
Sbjct: 1183 --EEATLQHEATAATLRKKHADSVAELGEQ--------IDNLQRVKQKLEKEKSEMKMEI 1232
Query: 365 KDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSE 424
DL N +SK A LE+ + L+ L + E+E + I+ L++ +++E
Sbjct: 1233 DDLASNM---ETVSK--AKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTE 1287
Query: 425 MGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKK----- 479
G+ ++ + + + KQ Q I +L+++L+ E +A+S + L +
Sbjct: 1288 SGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLL 1347
Query: 480 RKKLEEATAARAVAFAAASRGEC----------TETLRNRIRELEAEGKKLTMDMKVKED 529
R++ EE A+A A S+ T+ ++ R ELE KKL ++ E+
Sbjct: 1348 REQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQ-RTEELEEAKKKLAQRLQDAEE 1406
Query: 530 QIRELELKVQELRKYKEN-EKDTEVLM------SALSAMQDKTQ---------------- 566
+ + K L K K+ + + E LM +A A DK Q
Sbjct: 1407 HVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEE 1466
Query: 567 ---HLENSLSAETRIKLDLF---SALGDAKRQLEIAQGQILQKDQEIKDLKQKIAE 616
LE S + +LF +A ++ QLE + + QEI DL ++IAE
Sbjct: 1467 THAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAE 1522
Score = 55.1 bits (131), Expect = 2e-07
Identities = 55/253 (21%), Positives = 115/253 (45%), Gaps = 21/253 (8%)
Query: 383 LVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNA 442
L +Q ++ A+L+AS++ + L +++ + + ++ L++EN+ LQ ++ +
Sbjct: 1457 LAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDL 1516
Query: 443 VQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAAR-----------A 491
+ + + I +LEK K ++ +S ++ L E + + EE R
Sbjct: 1517 TEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEV 1576
Query: 492 VAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIR-----ELELKVQELRKYKE 546
A E + RN IR +E+ L +++ + D IR E +L E++
Sbjct: 1577 DRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHA 1636
Query: 547 NEKDTEVL---MSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQK 603
N E L + + ++D HL+++L ++ +K L A+ + + L A+ + L+
Sbjct: 1637 NRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQL--AMVERRANLLQAEIEELRA 1694
Query: 604 DQEIKDLKQKIAE 616
E + +KIAE
Sbjct: 1695 TLEQTERSRKIAE 1707
Score = 48.9 bits (115), Expect = 1e-05
Identities = 50/239 (20%), Positives = 102/239 (42%), Gaps = 14/239 (5%)
Query: 383 LVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERG----IRSEMGQLRQENELLQNK 438
+ ++++ +K K +L + +EL ++ +L + +++E L E
Sbjct: 853 MANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQL 912
Query: 439 LHNAVQMKQKDKQNISQLE--KKLKAEQEARSF-VEKQLMEEKKRKKLEEATAARAVAFA 495
+ +Q++ K K+ + E +++ AE A+ +E + E KK E T A+
Sbjct: 913 IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 972
Query: 496 AASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKENEKDTEVLM 555
A+ + + L + L+ KLT + K + E Q L + E L
Sbjct: 973 HATENK-VKNLTEEMAGLDETIAKLTKEKKALQ------EAHQQTLDDLQAEEDKVNTLT 1025
Query: 556 SALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKI 614
A ++ + LE SL E +I++DL A + L++AQ + + + + L +K+
Sbjct: 1026 KAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKL 1084
Score = 43.9 bits (102), Expect = 5e-04
Identities = 67/342 (19%), Positives = 135/342 (39%), Gaps = 53/342 (15%)
Query: 279 VDSKIQEIEYMENHINSKRLNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSA 338
+++KI+E+ E + + +N +L L ED C+ K+ + + + A
Sbjct: 919 LEAKIKEVT--ERAEDEEEINAELTAKKRKL--EDECSELKKDIDDLELTLAKVEKEKHA 974
Query: 339 TNGSIPSSSSK-----------NEKKQKCTSKSPSTHKDLMENCIPNNQLSKPDALVRLE 387
T + + + + ++K+ T DL N L+K A ++LE
Sbjct: 975 TENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTK--AKIKLE 1032
Query: 388 QDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQ 447
Q + L+ L+ +++ +L ER R G L+ E + +
Sbjct: 1033 QQVDDLEGSLEQEKKIRMDL----------ERAKRKLEGDLKLAQESTMDI--------E 1074
Query: 448 KDKQNISQLEKKLKAEQEARSFVEKQLMEEKK-----RKKLEEATA-----ARAVAFAAA 497
DKQ QL++KLK ++ S ++ ++ +E+ +KK++E A + A
Sbjct: 1075 NDKQ---QLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERA 1131
Query: 498 SRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKENEKDTEVLMSA 557
SR + + + RELE ++L QI + + E +K + + ++ + A
Sbjct: 1132 SRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEA 1191
Query: 558 LSAM-----QDKTQHLENSLSAETRIKLDLFSALGDAKRQLE 594
+A D L + R+K L + K +++
Sbjct: 1192 TAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1233
Score = 43.5 bits (101), Expect = 6e-04
Identities = 85/465 (18%), Positives = 193/465 (41%), Gaps = 71/465 (15%)
Query: 170 FKSYVSYKMRLRKQKEVQKENEFYMQLLQQALPP---------EQQMLQKQ-EKEAEEAA 219
FK +Y+ L + + +++EN+ Q + E + ++KQ E+E E
Sbjct: 1486 FKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQ 1545
Query: 220 KGLPDMDSSILIHHNGGI-PANKKLSTTLPEIEYREKGKEKDKDAKKHN----------- 267
L + ++S L H G I +L+ E++ + K+++ D K N
Sbjct: 1546 AALEEAEAS-LEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQST 1604
Query: 268 --LGINNNN----ILQPVDSKIQEIEYMENHIN---SKRLNNDLVGSTENLLKE-----D 313
I + N + + ++ + E+E NH N ++ L N +T+ +LK+ D
Sbjct: 1605 LDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRN--YRNTQAILKDTQLHLD 1662
Query: 314 SCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPSTHKDLMENCIP 373
S ++ K +V A + ++ + E+ +K + + ++ +
Sbjct: 1663 DALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQ-LLH 1721
Query: 374 NNQLSKPDALVRLEQDIKKLKADL----QASRQVEQELRSQISSLSSTERGIRSEMG--- 426
S + +LE DI +++ ++ Q +R E++ + I+ + ++ E
Sbjct: 1722 TQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSA 1781
Query: 427 -------QLRQENELLQNKLHNAVQMK--------QKDKQNISQLEKKLKAEQEARSFVE 471
L Q + LQ++L A Q+ QK + + +LE ++++EQ+
Sbjct: 1782 HLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAV 1841
Query: 472 KQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQI 531
K L K +K++E T + + L++ + +L+A+ K + E+Q
Sbjct: 1842 KGL--RKHERKVKELT------YQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQS 1893
Query: 532 RELELKVQELR-KYKENEKDTEVLMSALSAMQDKTQHLENSLSAE 575
K + ++ + +E E+ ++ S ++ ++ K++ + + +E
Sbjct: 1894 NVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSREVHTKIISE 1938
Score = 40.8 bits (94), Expect = 0.004
Identities = 70/390 (17%), Positives = 165/390 (42%), Gaps = 50/390 (12%)
Query: 251 EYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNNDLVGSTENLL 310
E ++K ++ +DA++H ++ V++K +E + + ++ DL+ E
Sbjct: 1392 EAKKKLAQRLQDAEEH---------VEAVNAKCASLEKTKQRLQNEV--EDLMIDVERT- 1439
Query: 311 KEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPSTHKDLMEN 370
+C A K +N ++ + T+ + +S ++ K + +++ ++
Sbjct: 1440 -NAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQ 1498
Query: 371 CIP------NNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSE 424
N Q D ++ + K++ + +QVEQE ++L E + E
Sbjct: 1499 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHE 1558
Query: 425 MGQ-LRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEE----KK 479
G+ LR + EL Q K ++ +KD++ ++ + +S ++ ++ +
Sbjct: 1559 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRL 1618
Query: 480 RKKLEEATAARAVAFAAASRGECTETLRN-RIRELEAEGKKLTMDMKVK-EDQIRE---- 533
+KK+E + A+R E LRN R + + +L +D ++ ++ ++E
Sbjct: 1619 KKKMEGDLNEMEIQLNHANR-MAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAM 1677
Query: 534 -------LELKVQELR-KYKENEKDTEVLMSALSAMQDKTQ--HLENSLSAETRIKLDLF 583
L+ +++ELR ++ E+ ++ L ++ Q H +N+ T+ KL+
Sbjct: 1678 VERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLE-- 1735
Query: 584 SALGDAKRQLEIAQGQILQKDQEIKDLKQK 613
+ QG++ QE ++ ++K
Sbjct: 1736 -------TDISQIQGEMEDIIQEARNAEEK 1758
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 68.9 bits (167), Expect = 1e-11
Identities = 90/395 (22%), Positives = 179/395 (45%), Gaps = 53/395 (13%)
Query: 262 DAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNNDLVGSTENLLKEDSCTASSKN 321
DA++ G+ + IL +++K++E+ E + +N++LV NL ED C++ ++
Sbjct: 904 DAEERCEGLIKSKIL--LEAKVKELT--ERLEEEEEMNSELVAKKRNL--EDKCSSLKRD 957
Query: 322 YKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPSTHKDLME---NCIPNNQL- 377
+ + + AT + + S + ++ SK K L E + + Q+
Sbjct: 958 IDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVE 1017
Query: 378 -SKPDALVR---------------LEQDIKKLKADLQ-ASRQVEQELR---SQISSLSST 417
K + L++ LEQ+ KKL+ADL+ A R++E +L+ I L +
Sbjct: 1018 EDKVNGLIKINAKLEQQTDDLEGSLEQE-KKLRADLERAKRKLEGDLKMSQESIMDLEND 1076
Query: 418 ERGIRSEMGQLRQENELLQNKLH----NAVQMKQKDKQ---NISQLEKKLKAEQEARSFV 470
++ I ++ + E LQ K+ +++Q ++K K+ I +LE++++AE R+ +
Sbjct: 1077 KQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKI 1136
Query: 471 EKQLME-----EKKRKKLEEATAARAVAFAAASRGECT-ETLRNRIRELEAEGKKLTMDM 524
EKQ + E+ ++LEEA+ A + + E + +R + E + + +
Sbjct: 1137 EKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATL 1196
Query: 525 KVKE-DQIRELELKVQELRKYKEN-EKDTEVLMSALSAMQDKTQHLENSLSAETRIKLDL 582
+ K+ D + EL ++ L++ K+ EK+ L + M + L S S R +
Sbjct: 1197 RKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTV 1256
Query: 583 FSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAEV 617
+ K + E Q+ Q I DL + A +
Sbjct: 1257 EDQFSEIKAKDE-------QQTQLIHDLNMQKARL 1284
Score = 63.2 bits (152), Expect = 8e-10
Identities = 92/476 (19%), Positives = 198/476 (41%), Gaps = 32/476 (6%)
Query: 177 KMRLRKQK-EVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNG 235
+ ++ KQ+ ++ +E E + L++A ++ +K E K D++ + L H
Sbjct: 1133 RAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEAT 1192
Query: 236 GIPANKKLSTTLPEIE------YREKGK-EKDKDAKKHNLGINNNNI--LQPVDSKIQE- 285
KK + ++ E+ R K K EK+K K + +NI L S I+
Sbjct: 1193 AATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERT 1252
Query: 286 ---IEYMENHINSKRLNNDLVGSTENLLKEDSCTAS---SKNYKNASGVVNSSPRSHSAT 339
+E + I +K + N+ K T + S + +++ +S A
Sbjct: 1253 CRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQAL 1312
Query: 340 NGSIPSSSSKNEKKQKCTSKSPSTHKDLMENC--IPNNQLSKPDALVRLEQDIKKLKADL 397
+ + E++ K + + +C + + +A L++ + K +++
Sbjct: 1313 TQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEV 1372
Query: 398 QASR-QVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQL 456
R + E + + L ++ + + + + E +K + + KQ+ + + L
Sbjct: 1373 AQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDL 1432
Query: 457 EKKLKAEQEARSFVEKQLMEEKK-----RKKLEEATAARAVAFAAASRGECTET--LRNR 509
+ L+ A + ++K+ K ++KL+E+ A A SR TE +RN
Sbjct: 1433 MRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAA-QKESRSLSTELFKMRNA 1491
Query: 510 IRELEAEGKKLTMDMKVKEDQIRELELKVQELRK-YKENEKDTEVLMSALSAMQDKTQHL 568
E+ + + L + K +++I +L ++ E K +E EK +++ S +Q + +
Sbjct: 1492 YEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEV 1551
Query: 569 ENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAEVMAVMPSI 624
E SL E L + L K +L+ ++++KD+EI+ LK+ + S+
Sbjct: 1552 EGSLEHEESKILRVQLELSQVKSELD---RKVIEKDEEIEQLKRNSQRAAEALQSV 1604
Score = 55.8 bits (133), Expect = 1e-07
Identities = 83/453 (18%), Positives = 186/453 (41%), Gaps = 50/453 (11%)
Query: 185 EVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKKLS 244
E++ ++E QL+ L ++ LQ Q E + + S + + + L+
Sbjct: 1262 EIKAKDEQQTQLIHD-LNMQKARLQTQNGELSHRVEEKESLISQLT-------KSKQALT 1313
Query: 245 TTLPEIEYREKGKEKDKDAKKHNLGINNNN--ILQPVDSKIQEIEYMENHINSKRLNNDL 302
L E++ + + + K K+A H L + ++ +L+ + QE + SK N
Sbjct: 1314 QQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKA--NSE 1371
Query: 303 VGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPS 362
V + D+ + + + + + T + +S + KQ+ +
Sbjct: 1372 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVED 1431
Query: 363 THKDLMEN-----CIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSST 417
+DL + + Q + L +Q + + +A+L+A+++ + L +++ + +
Sbjct: 1432 LMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNA 1491
Query: 418 ERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEE 477
+ ++ LR+EN+ LQ ++ + + + +N+ + EK K ++ +S ++ L E
Sbjct: 1492 YEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEV 1551
Query: 478 KKRKKLEEATAARAVAFAAASRGECTETL-----------RNRIRELEAEGKKLTMDMKV 526
+ + EE+ R + + E + RN R EA L +++
Sbjct: 1552 EGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRS 1611
Query: 527 KEDQIR-----ELELKVQELRKYKENEKDTEV---LMSALSAMQDKTQHLENSLSAETRI 578
+ D +R E +L E++ N + E L + ++D HL+++L +
Sbjct: 1612 RNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNE-- 1669
Query: 579 KLDLFSALGDAKRQLEIAQ---GQILQKDQEIK 608
D K QL I + G +L++ +E+K
Sbjct: 1670 ---------DLKEQLAIVERRNGLLLEELEEMK 1693
Score = 37.7 bits (86), Expect = 0.034
Identities = 65/391 (16%), Positives = 154/391 (39%), Gaps = 45/391 (11%)
Query: 186 VQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKKLST 245
VQ E L + + + + +++ ++ ++ AA+ L + + + N + KK+
Sbjct: 1565 VQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEG 1624
Query: 246 TLPEIEYR-----------------EKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEY 288
L E+E + +G+ KD + +N ++ + + +
Sbjct: 1625 DLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGL 1684
Query: 289 MENHINSKRLNNDLVGSTENLLKEDSCTASSKN---YKNASGVVNSSPR-------SHSA 338
+ + ++ + T L +++ AS + + + ++N+ + +
Sbjct: 1685 LLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAE 1744
Query: 339 TNGSIPSSSSKNEKKQKCTSKSPSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQ 398
SI S + EK +K + + ++L + + L + LEQ +K L+ L
Sbjct: 1745 VENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK--NLEQTVKDLQHRLD 1802
Query: 399 ASRQVEQELRSQISSLSSTERGIRSEMGQLRQ-ENELLQNKLHNAVQMKQKDKQNISQLE 457
+ Q+ +L ++ I+ ++R+ ENEL + A +K K E
Sbjct: 1803 EAEQL---------ALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKE 1853
Query: 458 KKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAEG 517
+AE++ ++ + Q + +K + K+ ++ A E T +R R ++ E
Sbjct: 1854 MTYQAEEDHKNILRLQDLVDKLQAKV------KSYKRQAEEAEEQANTQLSRCRRVQHEL 1907
Query: 518 KKLTMDMKVKEDQIRELELKVQELRKYKENE 548
++ + E Q+ +L K +++ K E
Sbjct: 1908 EEAAERADIAESQVNKLRAKSRDVGSQKMEE 1938
>gi|110611218 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 67.8 bits (164), Expect = 3e-11
Identities = 63/250 (25%), Positives = 125/250 (50%), Gaps = 17/250 (6%)
Query: 383 LVRLEQDIKKLKADLQASRQVE----QELRSQISSLSST-ERGIRSEMGQLRQENELLQN 437
LV EQ+I ++A +QAS + Q+L+ +I +L E G +++ +L+QEN +L++
Sbjct: 315 LVAREQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRD 374
Query: 438 KLHNAV-QMKQKDKQNISQLEKKL-KAEQEARSFVEKQLMEEKKRKKLEEATAA--RAVA 493
L+ A Q++ K +++L ++L K +E E +E++RK LE AA + V
Sbjct: 375 ALNQATSQVESKQNAELAKLRQELSKVSKELVEKSEAVRQDEQQRKALEAKAAAFEKQVL 434
Query: 494 FAAASRGECTETLRNRIRELEAE---GKKLTMDMKVKEDQIRELELKVQELR-KYKENEK 549
AS E E L+ R+ E+ E + ++ ++ +E + ++ EL K + +E
Sbjct: 435 QLQASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKLQSSEA 494
Query: 550 DTEVLMSALSAMQDKTQ--HLENSLSAETRIKLDLFSALGDAK--RQLEIAQGQILQKDQ 605
+ LS + + Q ENS E ++ G A+ + ++ +Q + Q+
Sbjct: 495 EVRSKCEELSGLHGQLQEARAENSQLTERIRSIEALLEAGQARDAQDVQASQAEADQQQT 554
Query: 606 EIKDLKQKIA 615
+K+L+ +++
Sbjct: 555 RLKELESQVS 564
Score = 46.2 bits (108), Expect = 1e-04
Identities = 55/247 (22%), Positives = 110/247 (44%), Gaps = 25/247 (10%)
Query: 376 QLSKPDALVR-LEQDIKKLKADLQASRQV-------EQELRSQISSLSSTERGIRSEMGQ 427
+L K V+ LE+ ++KLK +L++S QV E EL +++ S+ + E+
Sbjct: 733 ELQKSRVTVKHLEEIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAG 792
Query: 428 LRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEAT 487
LRQ Q++L A QK ++ + ++L E +S VE + EA
Sbjct: 793 LRQLLLESQSQLDAAKSEAQKQSDELALVRQQL---SEMKSHVEDGDIAGAPASS-PEAP 848
Query: 488 AARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKEN 547
A ++ E TE + + + + + +KLT + + + L+ ++++LR
Sbjct: 849 PAEQDPVQLKTQLEWTEAI---LEDEQTQRQKLTAEFEEAQTSACRLQEELEKLRTAGPL 905
Query: 548 EKDTEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEI 607
E S+ ++ L+ L E ++ DL A + L+ Q Q+ ++ +
Sbjct: 906 E----------SSETEEASQLKERLEKEKKLTSDLGRAATRLQELLKTTQEQLAREKDTV 955
Query: 608 KDLKQKI 614
K L++++
Sbjct: 956 KKLQEQL 962
Score = 45.1 bits (105), Expect = 2e-04
Identities = 77/359 (21%), Positives = 149/359 (41%), Gaps = 71/359 (19%)
Query: 347 SSKNEKKQKCTSKSPSTHKDLMENCIPNNQLSKP----DALV-----RLEQDIKKLKADL 397
SS+ E + KC S H L E N+QL++ +AL+ R QD++ +A+
Sbjct: 491 SSEAEVRSKCEELS-GLHGQLQEARAENSQLTERIRSIEALLEAGQARDAQDVQASQAEA 549
Query: 398 QASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQ----MKQKDKQNI 453
+ +EL SQ+S L +R + Q + +N L+ K A++ +Q K+ +
Sbjct: 550 DQQQTRLKELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEKL 609
Query: 454 SQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAAR---------------AVAFAAAS 498
L + + ++ +E Q ME E + A+ + +
Sbjct: 610 HSLTQAKEESEKQLCLIEAQTMEALLALLPELSVLAQQNYTEWLQDLKEKGPTLLKHPPA 669
Query: 499 RGECTETLRNRIRE-------LEAEGKKLTMDMKVKEDQIRELELKV------------- 538
E + L +++RE L+AE + + E +R+L+ V
Sbjct: 670 PAEPSSDLASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAKVGA 729
Query: 539 --QELRKYKENEKDTEVLMSALSA-------MQDKTQHLENSL-------SAE----TRI 578
+EL+K + K E ++ L +++ T HLE L SAE +
Sbjct: 730 AEEELQKSRVTVKHLEEIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKE 789
Query: 579 KLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAEVMAVMP--SITYSAATSPLSP 635
L L +++ QL+ A+ + ++ E+ ++Q+++E+ + + I + A+SP +P
Sbjct: 790 VAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGDIAGAPASSPEAP 848
Score = 42.7 bits (99), Expect = 0.001
Identities = 51/225 (22%), Positives = 99/225 (44%), Gaps = 37/225 (16%)
Query: 393 LKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQN 452
L+AD + +++ +Q++ S L S+E +RS+ +L + LH +Q + +
Sbjct: 468 LRADAEKAQEQQQQMAELHSKLQSSEAEVRSKCEEL--------SGLHGQLQEARAENSQ 519
Query: 453 ISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRNRIRE 512
+++ + ++A L EA AR AS+ E + + R++E
Sbjct: 520 LTERIRSIEA--------------------LLEAGQARDAQDVQASQAEADQQ-QTRLKE 558
Query: 513 LEAEGKKLTMDMKVKEDQIRELELKVQELRKYKENEKDTEVLMSALSAMQDK----TQHL 568
LE++ L + + + + ++K +LR ++N K E L +A A ++K TQ
Sbjct: 559 LESQVSGLEKEAIELREAVEQQKVKNNDLR--EKNWKAMEALATAEQACKEKLHSLTQAK 616
Query: 569 ENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQK 613
E S I+ AL +L + Q + ++DLK+K
Sbjct: 617 EESEKQLCLIEAQTMEALLALLPELSVLAQQ--NYTEWLQDLKEK 659
>gi|110611220 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 67.8 bits (164), Expect = 3e-11
Identities = 63/250 (25%), Positives = 125/250 (50%), Gaps = 17/250 (6%)
Query: 383 LVRLEQDIKKLKADLQASRQVE----QELRSQISSLSST-ERGIRSEMGQLRQENELLQN 437
LV EQ+I ++A +QAS + Q+L+ +I +L E G +++ +L+QEN +L++
Sbjct: 315 LVAREQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRD 374
Query: 438 KLHNAV-QMKQKDKQNISQLEKKL-KAEQEARSFVEKQLMEEKKRKKLEEATAA--RAVA 493
L+ A Q++ K +++L ++L K +E E +E++RK LE AA + V
Sbjct: 375 ALNQATSQVESKQNAELAKLRQELSKVSKELVEKSEAVRQDEQQRKALEAKAAAFEKQVL 434
Query: 494 FAAASRGECTETLRNRIRELEAE---GKKLTMDMKVKEDQIRELELKVQELR-KYKENEK 549
AS E E L+ R+ E+ E + ++ ++ +E + ++ EL K + +E
Sbjct: 435 QLQASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKLQSSEA 494
Query: 550 DTEVLMSALSAMQDKTQ--HLENSLSAETRIKLDLFSALGDAK--RQLEIAQGQILQKDQ 605
+ LS + + Q ENS E ++ G A+ + ++ +Q + Q+
Sbjct: 495 EVRSKCEELSGLHGQLQEARAENSQLTERIRSIEALLEAGQARDAQDVQASQAEADQQQT 554
Query: 606 EIKDLKQKIA 615
+K+L+ +++
Sbjct: 555 RLKELESQVS 564
Score = 46.2 bits (108), Expect = 1e-04
Identities = 55/247 (22%), Positives = 110/247 (44%), Gaps = 25/247 (10%)
Query: 376 QLSKPDALVR-LEQDIKKLKADLQASRQV-------EQELRSQISSLSSTERGIRSEMGQ 427
+L K V+ LE+ ++KLK +L++S QV E EL +++ S+ + E+
Sbjct: 733 ELQKSRVTVKHLEEIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAG 792
Query: 428 LRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEAT 487
LRQ Q++L A QK ++ + ++L E +S VE + EA
Sbjct: 793 LRQLLLESQSQLDAAKSEAQKQSDELALVRQQL---SEMKSHVEDGDIAGAPASS-PEAP 848
Query: 488 AARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKEN 547
A ++ E TE + + + + + +KLT + + + L+ ++++LR
Sbjct: 849 PAEQDPVQLKTQLEWTEAI---LEDEQTQRQKLTAEFEEAQTSACRLQEELEKLRTAGPL 905
Query: 548 EKDTEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEI 607
E S+ ++ L+ L E ++ DL A + L+ Q Q+ ++ +
Sbjct: 906 E----------SSETEEASQLKERLEKEKKLTSDLGRAATRLQELLKTTQEQLAREKDTV 955
Query: 608 KDLKQKI 614
K L++++
Sbjct: 956 KKLQEQL 962
Score = 45.1 bits (105), Expect = 2e-04
Identities = 77/359 (21%), Positives = 149/359 (41%), Gaps = 71/359 (19%)
Query: 347 SSKNEKKQKCTSKSPSTHKDLMENCIPNNQLSKP----DALV-----RLEQDIKKLKADL 397
SS+ E + KC S H L E N+QL++ +AL+ R QD++ +A+
Sbjct: 491 SSEAEVRSKCEELS-GLHGQLQEARAENSQLTERIRSIEALLEAGQARDAQDVQASQAEA 549
Query: 398 QASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQ----MKQKDKQNI 453
+ +EL SQ+S L +R + Q + +N L+ K A++ +Q K+ +
Sbjct: 550 DQQQTRLKELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEKL 609
Query: 454 SQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAAR---------------AVAFAAAS 498
L + + ++ +E Q ME E + A+ + +
Sbjct: 610 HSLTQAKEESEKQLCLIEAQTMEALLALLPELSVLAQQNYTEWLQDLKEKGPTLLKHPPA 669
Query: 499 RGECTETLRNRIRE-------LEAEGKKLTMDMKVKEDQIRELELKV------------- 538
E + L +++RE L+AE + + E +R+L+ V
Sbjct: 670 PAEPSSDLASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAKVGA 729
Query: 539 --QELRKYKENEKDTEVLMSALSA-------MQDKTQHLENSL-------SAE----TRI 578
+EL+K + K E ++ L +++ T HLE L SAE +
Sbjct: 730 AEEELQKSRVTVKHLEEIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKE 789
Query: 579 KLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAEVMAVMP--SITYSAATSPLSP 635
L L +++ QL+ A+ + ++ E+ ++Q+++E+ + + I + A+SP +P
Sbjct: 790 VAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGDIAGAPASSPEAP 848
Score = 42.7 bits (99), Expect = 0.001
Identities = 51/225 (22%), Positives = 99/225 (44%), Gaps = 37/225 (16%)
Query: 393 LKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQN 452
L+AD + +++ +Q++ S L S+E +RS+ +L + LH +Q + +
Sbjct: 468 LRADAEKAQEQQQQMAELHSKLQSSEAEVRSKCEEL--------SGLHGQLQEARAENSQ 519
Query: 453 ISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRNRIRE 512
+++ + ++A L EA AR AS+ E + + R++E
Sbjct: 520 LTERIRSIEA--------------------LLEAGQARDAQDVQASQAEADQQ-QTRLKE 558
Query: 513 LEAEGKKLTMDMKVKEDQIRELELKVQELRKYKENEKDTEVLMSALSAMQDK----TQHL 568
LE++ L + + + + ++K +LR ++N K E L +A A ++K TQ
Sbjct: 559 LESQVSGLEKEAIELREAVEQQKVKNNDLR--EKNWKAMEALATAEQACKEKLHSLTQAK 616
Query: 569 ENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQK 613
E S I+ AL +L + Q + ++DLK+K
Sbjct: 617 EESEKQLCLIEAQTMEALLALLPELSVLAQQ--NYTEWLQDLKEK 659
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 67.8 bits (164), Expect = 3e-11
Identities = 100/475 (21%), Positives = 183/475 (38%), Gaps = 77/475 (16%)
Query: 185 EVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKKLS 244
E K+ EF M LQ + EQ + + +K+ +E + +++ I A K+ S
Sbjct: 1082 EKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1141
Query: 245 TTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNNDLVG 304
E+E + E+ A + +N K +E E+ +++ DL
Sbjct: 1142 DLSRELEEISERLEEAGGATSAQIEMN----------KKREAEF-------QKMRRDLEE 1184
Query: 305 STENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPSTH 364
ST + TA++ K+A V + S K+E K +
Sbjct: 1185 ST----LQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEI-------- 1232
Query: 365 KDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSE 424
N + +N + A E+ + L+ L + E+E + I+ LS+ + + +E
Sbjct: 1233 -----NDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTE 1287
Query: 425 MGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARS--------------FV 470
G+ ++ + + + KQ Q I +L+++L+ E +A+S +
Sbjct: 1288 SGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLL 1347
Query: 471 EKQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQ 530
+Q EE++ K + ++A + A R + R ELE KKL ++ E+
Sbjct: 1348 REQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEH 1407
Query: 531 IRELELKVQELRKYKEN-EKDTEVLM------SALSAMQDKTQ----------------- 566
+ + K L K K+ + + E LM +A DK Q
Sbjct: 1408 VEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEET 1467
Query: 567 --HLENSLSAETRIKLDLF---SALGDAKRQLEIAQGQILQKDQEIKDLKQKIAE 616
LE S + +LF +A ++ LE + + QEI DL ++IAE
Sbjct: 1468 QAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAE 1522
Score = 61.2 bits (147), Expect = 3e-09
Identities = 89/466 (19%), Positives = 200/466 (42%), Gaps = 37/466 (7%)
Query: 170 FKSYVSYKMRLRKQKEVQKENEFYMQLLQQALPP---------EQQMLQKQ-EKEAEEAA 219
FK +Y+ L + +++EN+ Q + E + ++KQ + E E
Sbjct: 1486 FKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQ 1545
Query: 220 KGLPDMDSSILIHHNGGIPANKKLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPV 279
L + ++S L H G I ++ L +++ K +KD + L N+ +++ +
Sbjct: 1546 TSLEEAEAS-LEHEEGKI---LRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESM 1601
Query: 280 DSKIQ-EIEYMENHINSKRLNNDLVGSTENLLKEDSCTASS--KNYKNASGVVNSSPRSH 336
S + EI + + K+ + E L + A+ +N +N G++ +
Sbjct: 1602 QSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLH- 1660
Query: 337 SATNGSIPSSSSKNEKKQKCTSKSPSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKAD 396
+ +I E+ ++ +LM+ + + S L R E+ K + +
Sbjct: 1661 --LDDAIRGQDDLKEQLAMVERRA-----NLMQAEVEELRAS----LERTERGRKMAEQE 1709
Query: 397 LQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQL 456
L + + Q L +Q +SL +T++ + +++ Q++ E E + + NA + +K + + +
Sbjct: 1710 LLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMM 1769
Query: 457 EKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAE 516
++LK EQ+ + +E+ ++ K + A A + + L R+RELE+E
Sbjct: 1770 AEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESE 1829
Query: 517 -------GKKLTMDMKVKEDQIRELELKVQELRKYKENEKD-TEVLMSALSAMQDKTQHL 568
+ ++ E +++EL + +E RK +D + L + + A + + +
Sbjct: 1830 VESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEA 1889
Query: 569 ENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKI 614
E + L L +AK + +IA+ Q+ + + +++ K+
Sbjct: 1890 EEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSREVHTKV 1935
Score = 55.8 bits (133), Expect = 1e-07
Identities = 94/421 (22%), Positives = 173/421 (41%), Gaps = 97/421 (23%)
Query: 279 VDSKIQEIEYMENHINSKRLNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSA 338
+++KI+E+ E + + +N +L L ED C+ K+ + + + A
Sbjct: 919 LEAKIKEVT--ERAEDEEEINAELTAKKRKL--EDECSELKKDIDDLELTLAKVEKEKHA 974
Query: 339 TNGSIPSSSSK-----------NEKKQKCTSKSPSTHKDLMENCIPNNQLSKPDALVRLE 387
T + + + + ++K+ T DL N L+K A +LE
Sbjct: 975 TENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTK--AKTKLE 1032
Query: 388 QDI----------KKLKADLQ-ASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQ 436
Q + KKL DL+ A R++E +L+ S TE ++ QL ++ + +
Sbjct: 1033 QQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTE----NDKQQLNEKLKKKE 1088
Query: 437 NKLHNAVQMKQKDKQNIS-QLEKKLK--------------AEQEARSFVEKQLME----- 476
++ N +Q K +D+Q ++ QL+KK+K AE+ +R+ EKQ +
Sbjct: 1089 FEMSN-LQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSREL 1147
Query: 477 ----------------------------EKKRKKLEEATAARAVAFAAASR--GECTETL 506
+K R+ LEE+T AA + + L
Sbjct: 1148 EEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAEL 1207
Query: 507 RNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKEN-EKDTEVL---MSALSAMQ 562
+I L+ +KL + + +I +L ++ + K K N EK L +S + +
Sbjct: 1208 GEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKE 1267
Query: 563 DKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKD-------QEIKDLKQKIA 615
++ Q L N LSA+ K L + G+ RQL+ + Q Q+I++LK+++
Sbjct: 1268 EEQQRLINELSAQ---KARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLE 1324
Query: 616 E 616
E
Sbjct: 1325 E 1325
Score = 52.0 bits (123), Expect = 2e-06
Identities = 52/253 (20%), Positives = 117/253 (46%), Gaps = 21/253 (8%)
Query: 383 LVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNA 442
L +Q ++ +A+L+AS++ + L +++ + + + L++EN+ LQ ++ +
Sbjct: 1457 LAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDL 1516
Query: 443 VQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAAR----------AV 492
+ + ++I +LEK K +S ++ L E + + EE R +
Sbjct: 1517 TEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEI 1576
Query: 493 AFAAASRGECTETL-RNRIRELEAEGKKLTMDMKVKEDQIR-----ELELKVQELRKYKE 546
A + E + L RN +R +E+ L +++ + D +R E +L E++
Sbjct: 1577 DRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHA 1636
Query: 547 NEKDTEVLMSALSA---MQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQK 603
N + E L + + ++D HL++++ + +K L A+ + + L A+ + L+
Sbjct: 1637 NRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQL--AMVERRANLMQAEVEELRA 1694
Query: 604 DQEIKDLKQKIAE 616
E + +K+AE
Sbjct: 1695 SLERTERGRKMAE 1707
Score = 47.8 bits (112), Expect = 3e-05
Identities = 49/239 (20%), Positives = 102/239 (42%), Gaps = 14/239 (5%)
Query: 383 LVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERG----IRSEMGQLRQENELLQNK 438
+ ++++ +K K +L + +EL ++ +L + +++E L E
Sbjct: 853 MANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQL 912
Query: 439 LHNAVQMKQKDKQNISQLE--KKLKAEQEARSF-VEKQLMEEKKRKKLEEATAARAVAFA 495
+ +Q++ K K+ + E +++ AE A+ +E + E KK E T A+
Sbjct: 913 IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 972
Query: 496 AASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKENEKDTEVLM 555
A+ + + L + L+ KLT + K + E Q L + E L
Sbjct: 973 HATENK-VKNLTEEMAGLDETIAKLTKEKKALQ------EAHQQTLDDLQMEEDKVNTLT 1025
Query: 556 SALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKI 614
A + ++ + LE SL E ++ +DL A + L++AQ + + + + L +K+
Sbjct: 1026 KAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKL 1084
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 66.2 bits (160), Expect = 9e-11
Identities = 79/402 (19%), Positives = 167/402 (41%), Gaps = 51/402 (12%)
Query: 189 ENEFYMQ-----LLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKKL 243
EN ++Q + +A +Q+ +K E+E +E + L D++ + HN
Sbjct: 924 ENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHN--------- 974
Query: 244 STTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNNDLV 303
E++ R + + K + N L + K++ ++ N+ L+
Sbjct: 975 --QCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLK---------GAREENSGLL 1023
Query: 304 GSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPST 363
E L K+ +++ ++A ++ + + T S+ + N K Q +
Sbjct: 1024 QELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQ-------NE 1076
Query: 364 HKDLMENCIPN-NQLSKPDALVRLE-QDIKKLKADLQASRQVEQELRSQISSLSSTERGI 421
L EN + N +L+K L+ +E Q +++ + +++ +Q + Q+S+L +
Sbjct: 1077 LDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKL 1136
Query: 422 RSEMG----------QLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVE 471
E+G +L +E +L N+L ++MK+++ + I +++ + Q++ S
Sbjct: 1137 AEELGRSRDEVTSHQKLEEERSVLNNQL---LEMKKRESKFIKDADEEKASLQKSISITS 1193
Query: 472 KQLMEE--KKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKED 529
L E+ + K E T R +A S +TL + +LE + K L + +K +
Sbjct: 1194 ALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKR 1253
Query: 530 QIREL--ELKVQELRKYKENEKDTEVLMSALSAMQDKTQHLE 569
Q+ Q + E + L S + +Q K Q L+
Sbjct: 1254 QLSSSSGNTDTQADEDERAQESQIDFLNSVIVDLQRKNQDLK 1295
Score = 44.3 bits (103), Expect = 4e-04
Identities = 54/275 (19%), Positives = 122/275 (44%), Gaps = 43/275 (15%)
Query: 359 KSPSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISS----- 413
K+ H ME+ + N+L + + V+ +++ L+A +V SQ+ +
Sbjct: 673 KAEDQHLVEMEDTL--NKLQEAEIKVK---ELEVLQAKCNEQTKVIDNFTSQLKATEEKL 727
Query: 414 -----LSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARS 468
L +SEM +LRQ+ E + ++ + K + S + ++L+ + +
Sbjct: 728 LDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLT 787
Query: 469 FVEKQLMEEKKRKK-LEEATAARAVAFAAAS------RGECTETLRNRIRELEAEGKKLT 521
+++ L E + K+ LE+ FA AS + ET+ N++ + E + L+
Sbjct: 788 NLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETV-NKLHQKEEQFNMLS 846
Query: 522 MDMKVKEDQIRELELKVQELRKYKENEKDTEVLMSALSAMQDKTQHLENSLSAETRIKLD 581
D++ + + ++E K++E ++ E L+ A + LEN ++ +
Sbjct: 847 SDLEKLRENLADME------AKFREKDEREEQLIKA-------KEKLENDIA-------E 886
Query: 582 LFSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAE 616
+ GD QL ++ K++++++L+ K+ +
Sbjct: 887 IMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTK 921
Score = 37.7 bits (86), Expect = 0.034
Identities = 42/209 (20%), Positives = 87/209 (41%), Gaps = 14/209 (6%)
Query: 181 RKQKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPAN 240
+K +E +KE E Q Q + ++ K AEE + ++ S + +
Sbjct: 1103 QKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSV--- 1159
Query: 241 KKLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNN 300
L+ L E++ RE KD D +K +L + + + K E+E + N + R N
Sbjct: 1160 --LNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGEN 1217
Query: 301 DLVGSTENLLK--EDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTS 358
S ++++ E KN + + R S+++G+ + + ++E+ Q+
Sbjct: 1218 ASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQE--- 1274
Query: 359 KSPSTHKDLMENCIPNNQLSKPDALVRLE 387
+ D + + I + Q D +++E
Sbjct: 1275 ----SQIDFLNSVIVDLQRKNQDLKMKVE 1299
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 66.2 bits (160), Expect = 9e-11
Identities = 79/402 (19%), Positives = 167/402 (41%), Gaps = 51/402 (12%)
Query: 189 ENEFYMQ-----LLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKKL 243
EN ++Q + +A +Q+ +K E+E +E + L D++ + HN
Sbjct: 959 ENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHN--------- 1009
Query: 244 STTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNNDLV 303
E++ R + + K + N L + K++ ++ N+ L+
Sbjct: 1010 --QCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLK---------GAREENSGLL 1058
Query: 304 GSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPST 363
E L K+ +++ ++A ++ + + T S+ + N K Q +
Sbjct: 1059 QELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQ-------NE 1111
Query: 364 HKDLMENCIPN-NQLSKPDALVRLE-QDIKKLKADLQASRQVEQELRSQISSLSSTERGI 421
L EN + N +L+K L+ +E Q +++ + +++ +Q + Q+S+L +
Sbjct: 1112 LDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKL 1171
Query: 422 RSEMG----------QLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVE 471
E+G +L +E +L N+L ++MK+++ + I +++ + Q++ S
Sbjct: 1172 AEELGRSRDEVTSHQKLEEERSVLNNQL---LEMKKRESKFIKDADEEKASLQKSISITS 1228
Query: 472 KQLMEE--KKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKED 529
L E+ + K E T R +A S +TL + +LE + K L + +K +
Sbjct: 1229 ALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKR 1288
Query: 530 QIREL--ELKVQELRKYKENEKDTEVLMSALSAMQDKTQHLE 569
Q+ Q + E + L S + +Q K Q L+
Sbjct: 1289 QLSSSSGNTDTQADEDERAQESQIDFLNSVIVDLQRKNQDLK 1330
Score = 44.3 bits (103), Expect = 4e-04
Identities = 54/275 (19%), Positives = 122/275 (44%), Gaps = 43/275 (15%)
Query: 359 KSPSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISS----- 413
K+ H ME+ + N+L + + V+ +++ L+A +V SQ+ +
Sbjct: 708 KAEDQHLVEMEDTL--NKLQEAEIKVK---ELEVLQAKCNEQTKVIDNFTSQLKATEEKL 762
Query: 414 -----LSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARS 468
L +SEM +LRQ+ E + ++ + K + S + ++L+ + +
Sbjct: 763 LDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLT 822
Query: 469 FVEKQLMEEKKRKK-LEEATAARAVAFAAAS------RGECTETLRNRIRELEAEGKKLT 521
+++ L E + K+ LE+ FA AS + ET+ N++ + E + L+
Sbjct: 823 NLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETV-NKLHQKEEQFNMLS 881
Query: 522 MDMKVKEDQIRELELKVQELRKYKENEKDTEVLMSALSAMQDKTQHLENSLSAETRIKLD 581
D++ + + ++E K++E ++ E L+ A + LEN ++ +
Sbjct: 882 SDLEKLRENLADME------AKFREKDEREEQLIKA-------KEKLENDIA-------E 921
Query: 582 LFSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAE 616
+ GD QL ++ K++++++L+ K+ +
Sbjct: 922 IMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTK 956
Score = 37.7 bits (86), Expect = 0.034
Identities = 42/209 (20%), Positives = 87/209 (41%), Gaps = 14/209 (6%)
Query: 181 RKQKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPAN 240
+K +E +KE E Q Q + ++ K AEE + ++ S + +
Sbjct: 1138 QKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSV--- 1194
Query: 241 KKLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNN 300
L+ L E++ RE KD D +K +L + + + K E+E + N + R N
Sbjct: 1195 --LNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGEN 1252
Query: 301 DLVGSTENLLK--EDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTS 358
S ++++ E KN + + R S+++G+ + + ++E+ Q+
Sbjct: 1253 ASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQE--- 1309
Query: 359 KSPSTHKDLMENCIPNNQLSKPDALVRLE 387
+ D + + I + Q D +++E
Sbjct: 1310 ----SQIDFLNSVIVDLQRKNQDLKMKVE 1334
>gi|188528616 testis specific, 10 [Homo sapiens]
Length = 698
Score = 65.9 bits (159), Expect = 1e-10
Identities = 88/425 (20%), Positives = 169/425 (39%), Gaps = 77/425 (18%)
Query: 205 QQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPA-NKKLSTTLPEIEYREKGKEKDKDA 263
++ + EKE + A+ D +S + G A N L E ++
Sbjct: 169 KETISTVEKEMKSLARKAMDTESEL-----GRQKAENNSLRLLYENTEKDLSDTQRHLAK 223
Query: 264 KKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNNDLVGSTENLLKEDSCTAS--SKN 321
KK+ L + I+ +D KI + +I + + L G+ +L KE C + K
Sbjct: 224 KKYELQLTQEKIMC-LDEKIDN--FTRQNIAQREEISILGGTLNDLAKEKECLQACLDKK 280
Query: 322 YKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPSTHKDLMENCIPNNQLSKPD 381
+N + + S +G + + ++CT +
Sbjct: 281 SENIASLGESLAMKEKTISGMKNIIAEMEQASRQCT-----------------------E 317
Query: 382 ALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLH- 440
AL+ EQD+ +++ L + ++ + L+ ++ + + +QEN+ L KL+
Sbjct: 318 ALIVCEQDVSRMRRQLDETNDELAQIARERDILAHDNDNLQEQFAKAKQENQALSKKLND 377
Query: 441 -----NAVQMKQKDKQ-NISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAF 494
N ++ K +D +++L+ LK+E+ E + M E+ RK E+A
Sbjct: 378 THNELNDIKQKVQDTNLEVNKLKNILKSEES-----ENRQMMEQLRKANEDA-------- 424
Query: 495 AAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKENEKDTE-V 553
E N+ R+ EA+ L +++ E + L+ KV L + E + E
Sbjct: 425 ---------ENWENKARQSEADNNTLKLELITAEAEGNRLKEKVDSLNREVEQHLNAERS 475
Query: 554 LMSALSAMQDKTQHLENSLSAETRIKLDLFSALGD--AKRQL--------EIAQGQILQK 603
S +S + +E L +++ + SAL D + R+L E+ Q++ K
Sbjct: 476 YKSQISTLHKSVVKMEEELQ---KVQFEKVSALADLSSTRELCIKLDSSKELLNRQLVAK 532
Query: 604 DQEIK 608
DQEI+
Sbjct: 533 DQEIE 537
Score = 40.4 bits (93), Expect = 0.005
Identities = 82/389 (21%), Positives = 158/389 (40%), Gaps = 69/389 (17%)
Query: 184 KEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDM--DSSILIHHNGGIPANK 241
K + E E + +AL +Q + + ++ +E L + + IL H N +
Sbjct: 302 KNIIAEMEQASRQCTEALIVCEQDVSRMRRQLDETNDELAQIARERDILAHDNDNL---- 357
Query: 242 KLSTTLPEIEYREKGKEKDKDAKKHNLGINN-NNILQPVDSKIQEIEYMENHINSKRLNN 300
+ ++ + +E +KK N N N+I Q V E+ ++N + S+ N
Sbjct: 358 -------QEQFAKAKQENQALSKKLNDTHNELNDIKQKVQDTNLEVNKLKNILKSEESEN 410
Query: 301 DLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKS 360
+ ED+ +N++N + S +++ I + + N K+K S +
Sbjct: 411 RQMMEQLRKANEDA-----ENWENKAR--QSEADNNTLKLELITAEAEGNRLKEKVDSLN 463
Query: 361 PSTHKDLMENCIPNNQLSK-PDALVRLEQDIKKLK-------ADLQASRQV--------- 403
+ L +Q+S ++V++E++++K++ ADL ++R++
Sbjct: 464 REVEQHLNAERSYKSQISTLHKSVVKMEEELQKVQFEKVSALADLSSTRELCIKLDSSKE 523
Query: 404 ---------EQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNIS 454
+QE+ + + L S I Q+ E +QN A+ + +DK+ S
Sbjct: 524 LLNRQLVAKDQEIEMRENELDSAHSEIELLRSQMANERISMQNL--EALLVANRDKEYQS 581
Query: 455 QLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRNRIRELE 514
Q+ + K E E + E + E K A +R VA RN + +LE
Sbjct: 582 QIALQEK-ESEIQLLKEHLCLAENKM-----AIQSRDVA-----------QFRNVVTQLE 624
Query: 515 AEGKKLTMDMKVKEDQIRELELKVQELRK 543
A+ L + + + E E VQELR+
Sbjct: 625 AD---LDITKRQLGTERFERERAVQELRR 650
Score = 39.3 bits (90), Expect = 0.012
Identities = 75/375 (20%), Positives = 150/375 (40%), Gaps = 56/375 (14%)
Query: 279 VDSKIQEIEYMENHINSKRLNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSA 338
++ +I+E+E ++++ +R+ S L+KE T + + S R
Sbjct: 140 LEQRIEELECTVHNLDDERMEQM---SNMTLMKETISTVEKE--------MKSLARKAMD 188
Query: 339 TNGSIPSSSSKNEKKQKCTSKSPSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQ 398
T + ++N + +T KDL + L+K ++L Q+ K + D +
Sbjct: 189 TESELGRQKAENNSLRLLYE---NTEKDLSDT---QRHLAKKKYELQLTQE-KIMCLDEK 241
Query: 399 ASRQVEQEL--RSQISSLSSTERGIRSEMGQLRQENELLQN----------KLHNAVQMK 446
Q + R +IS L T + L +E E LQ L ++ MK
Sbjct: 242 IDNFTRQNIAQREEISILGGT-------LNDLAKEKECLQACLDKKSENIASLGESLAMK 294
Query: 447 QKD----KQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEE-----ATAARAVAFAAA 497
+K K I+++E+ + EA E+ + + R++L+E A AR A
Sbjct: 295 EKTISGMKNIIAEMEQASRQCTEALIVCEQDV--SRMRRQLDETNDELAQIARERDILAH 352
Query: 498 SRGECTETLRNRIRELEAEGKKLT---MDMKVKEDQIRELELKVQELRKY-KENEKDTEV 553
E +E +A KKL ++ + ++++ L+V +L+ K E +
Sbjct: 353 DNDNLQEQFAKAKQENQALSKKLNDTHNELNDIKQKVQDTNLEVNKLKNILKSEESENRQ 412
Query: 554 LMSALSAMQDKTQHLEN----SLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKD 609
+M L + ++ EN S + +KL+L +A + R E + +Q +
Sbjct: 413 MMEQLRKANEDAENWENKARQSEADNNTLKLELITAEAEGNRLKEKVDSLNREVEQHLNA 472
Query: 610 LKQKIAEVMAVMPSI 624
+ +++ + S+
Sbjct: 473 ERSYKSQISTLHKSV 487
>gi|13376858 testis specific, 10 [Homo sapiens]
Length = 698
Score = 65.9 bits (159), Expect = 1e-10
Identities = 88/425 (20%), Positives = 169/425 (39%), Gaps = 77/425 (18%)
Query: 205 QQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPA-NKKLSTTLPEIEYREKGKEKDKDA 263
++ + EKE + A+ D +S + G A N L E ++
Sbjct: 169 KETISTVEKEMKSLARKAMDTESEL-----GRQKAENNSLRLLYENTEKDLSDTQRHLAK 223
Query: 264 KKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNNDLVGSTENLLKEDSCTAS--SKN 321
KK+ L + I+ +D KI + +I + + L G+ +L KE C + K
Sbjct: 224 KKYELQLTQEKIMC-LDEKIDN--FTRQNIAQREEISILGGTLNDLAKEKECLQACLDKK 280
Query: 322 YKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPSTHKDLMENCIPNNQLSKPD 381
+N + + S +G + + ++CT +
Sbjct: 281 SENIASLGESLAMKEKTISGMKNIIAEMEQASRQCT-----------------------E 317
Query: 382 ALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLH- 440
AL+ EQD+ +++ L + ++ + L+ ++ + + +QEN+ L KL+
Sbjct: 318 ALIVCEQDVSRMRRQLDETNDELAQIARERDILAHDNDNLQEQFAKAKQENQALSKKLND 377
Query: 441 -----NAVQMKQKDKQ-NISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAF 494
N ++ K +D +++L+ LK+E+ E + M E+ RK E+A
Sbjct: 378 THNELNDIKQKVQDTNLEVNKLKNILKSEES-----ENRQMMEQLRKANEDA-------- 424
Query: 495 AAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKENEKDTE-V 553
E N+ R+ EA+ L +++ E + L+ KV L + E + E
Sbjct: 425 ---------ENWENKARQSEADNNTLKLELITAEAEGNRLKEKVDSLNREVEQHLNAERS 475
Query: 554 LMSALSAMQDKTQHLENSLSAETRIKLDLFSALGD--AKRQL--------EIAQGQILQK 603
S +S + +E L +++ + SAL D + R+L E+ Q++ K
Sbjct: 476 YKSQISTLHKSVVKMEEELQ---KVQFEKVSALADLSSTRELCIKLDSSKELLNRQLVAK 532
Query: 604 DQEIK 608
DQEI+
Sbjct: 533 DQEIE 537
Score = 40.4 bits (93), Expect = 0.005
Identities = 82/389 (21%), Positives = 158/389 (40%), Gaps = 69/389 (17%)
Query: 184 KEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDM--DSSILIHHNGGIPANK 241
K + E E + +AL +Q + + ++ +E L + + IL H N +
Sbjct: 302 KNIIAEMEQASRQCTEALIVCEQDVSRMRRQLDETNDELAQIARERDILAHDNDNL---- 357
Query: 242 KLSTTLPEIEYREKGKEKDKDAKKHNLGINN-NNILQPVDSKIQEIEYMENHINSKRLNN 300
+ ++ + +E +KK N N N+I Q V E+ ++N + S+ N
Sbjct: 358 -------QEQFAKAKQENQALSKKLNDTHNELNDIKQKVQDTNLEVNKLKNILKSEESEN 410
Query: 301 DLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKS 360
+ ED+ +N++N + S +++ I + + N K+K S +
Sbjct: 411 RQMMEQLRKANEDA-----ENWENKAR--QSEADNNTLKLELITAEAEGNRLKEKVDSLN 463
Query: 361 PSTHKDLMENCIPNNQLSK-PDALVRLEQDIKKLK-------ADLQASRQV--------- 403
+ L +Q+S ++V++E++++K++ ADL ++R++
Sbjct: 464 REVEQHLNAERSYKSQISTLHKSVVKMEEELQKVQFEKVSALADLSSTRELCIKLDSSKE 523
Query: 404 ---------EQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNIS 454
+QE+ + + L S I Q+ E +QN A+ + +DK+ S
Sbjct: 524 LLNRQLVAKDQEIEMRENELDSAHSEIELLRSQMANERISMQNL--EALLVANRDKEYQS 581
Query: 455 QLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRNRIRELE 514
Q+ + K E E + E + E K A +R VA RN + +LE
Sbjct: 582 QIALQEK-ESEIQLLKEHLCLAENKM-----AIQSRDVA-----------QFRNVVTQLE 624
Query: 515 AEGKKLTMDMKVKEDQIRELELKVQELRK 543
A+ L + + + E E VQELR+
Sbjct: 625 AD---LDITKRQLGTERFERERAVQELRR 650
Score = 39.3 bits (90), Expect = 0.012
Identities = 75/375 (20%), Positives = 150/375 (40%), Gaps = 56/375 (14%)
Query: 279 VDSKIQEIEYMENHINSKRLNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSA 338
++ +I+E+E ++++ +R+ S L+KE T + + S R
Sbjct: 140 LEQRIEELECTVHNLDDERMEQM---SNMTLMKETISTVEKE--------MKSLARKAMD 188
Query: 339 TNGSIPSSSSKNEKKQKCTSKSPSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQ 398
T + ++N + +T KDL + L+K ++L Q+ K + D +
Sbjct: 189 TESELGRQKAENNSLRLLYE---NTEKDLSDT---QRHLAKKKYELQLTQE-KIMCLDEK 241
Query: 399 ASRQVEQEL--RSQISSLSSTERGIRSEMGQLRQENELLQN----------KLHNAVQMK 446
Q + R +IS L T + L +E E LQ L ++ MK
Sbjct: 242 IDNFTRQNIAQREEISILGGT-------LNDLAKEKECLQACLDKKSENIASLGESLAMK 294
Query: 447 QKD----KQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEE-----ATAARAVAFAAA 497
+K K I+++E+ + EA E+ + + R++L+E A AR A
Sbjct: 295 EKTISGMKNIIAEMEQASRQCTEALIVCEQDV--SRMRRQLDETNDELAQIARERDILAH 352
Query: 498 SRGECTETLRNRIRELEAEGKKLT---MDMKVKEDQIRELELKVQELRKY-KENEKDTEV 553
E +E +A KKL ++ + ++++ L+V +L+ K E +
Sbjct: 353 DNDNLQEQFAKAKQENQALSKKLNDTHNELNDIKQKVQDTNLEVNKLKNILKSEESENRQ 412
Query: 554 LMSALSAMQDKTQHLEN----SLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKD 609
+M L + ++ EN S + +KL+L +A + R E + +Q +
Sbjct: 413 MMEQLRKANEDAENWENKARQSEADNNTLKLELITAEAEGNRLKEKVDSLNREVEQHLNA 472
Query: 610 LKQKIAEVMAVMPSI 624
+ +++ + S+
Sbjct: 473 ERSYKSQISTLHKSV 487
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 65.9 bits (159), Expect = 1e-10
Identities = 102/476 (21%), Positives = 191/476 (40%), Gaps = 79/476 (16%)
Query: 185 EVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKKLS 244
E K+ EF + LQ + EQ + + +K+ +E + +++ I A K+ S
Sbjct: 1084 EKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1143
Query: 245 TTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNNDLVG 304
E+E + E+ A + +N K +E E+ +++ DL
Sbjct: 1144 DLSRELEEISERLEEAGGATSAQIEMN----------KKREAEF-------QKMRRDL-- 1184
Query: 305 STENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPSTH 364
E + TA++ K+A V + I + +K +K S+
Sbjct: 1185 --EEATLQHEATAATLRKKHADSVAELGEQ--------IDNLQRVKQKLEKEKSEMKMEI 1234
Query: 365 KDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSE 424
DL N +SK A LE+ + L+ L + E+E + I+ L++ +++E
Sbjct: 1235 DDLASNV---ETVSK--AKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTE 1289
Query: 425 MGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKK----- 479
G+ ++ + + + + KQ Q I +L+++L+ E +A++ + L +
Sbjct: 1290 SGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLL 1349
Query: 480 RKKLEEATAARAVAFAAASRGECTETLR----------NRIRELEAEGKKLTMDMKVKED 529
R++ EE ++A A S+ TE + R ELE KKL ++ E+
Sbjct: 1350 REQYEEEQESKAELQRALSKAN-TEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEE 1408
Query: 530 QIRELELKVQELRKYKEN-EKDTEVLM------SALSAMQDKTQHLENSLSAETRIKLD- 581
+ + K L K K+ + + E LM +A A DK Q + + AE + K +
Sbjct: 1409 HVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEE 1468
Query: 582 ---------------------LFSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAE 616
+ +A ++ QLE + + QEI DL ++IAE
Sbjct: 1469 THAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAE 1524
Score = 63.5 bits (153), Expect = 6e-10
Identities = 92/466 (19%), Positives = 202/466 (43%), Gaps = 37/466 (7%)
Query: 170 FKSYVSYKMRLRKQKEVQKENEFYMQLLQQALPP---------EQQMLQKQ-EKEAEEAA 219
FK +Y+ L + + +++EN+ Q + E + ++KQ E+E E
Sbjct: 1488 FKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQ 1547
Query: 220 KGLPDMDSSILIHHNGGIPANKKLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPV 279
L + ++S L H G I ++ L +++ K +KD + L N+ I++ +
Sbjct: 1548 AALEEAEAS-LEHEEGKI---LRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESM 1603
Query: 280 DSKIQ-EIEYMENHIN-SKRLNNDLVGSTENLLKEDSCTASS-KNYKNASGVVNSSPRSH 336
S + EI + I K++ DL L + A + +NY+N G++ +
Sbjct: 1604 QSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDT---Q 1660
Query: 337 SATNGSIPSSSSKNEKKQKCTSKSPSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKAD 396
+ ++ S E+ ++ ++ E Q + + EQ++
Sbjct: 1661 IHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIA--EQEL------ 1712
Query: 397 LQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQL 456
L AS +V Q L +Q +SL +T++ + +++ Q++ E E + + NA + +K + + +
Sbjct: 1713 LDASERV-QLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMM 1771
Query: 457 EKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAE 516
++LK EQ+ + +E+ ++ K + A A + + L R+RELE E
Sbjct: 1772 AEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGE 1831
Query: 517 -------GKKLTMDMKVKEDQIRELELKVQELRKYKENEKD-TEVLMSALSAMQDKTQHL 568
+ ++ E +++EL + +E RK +D + L + + + + + +
Sbjct: 1832 VESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEA 1891
Query: 569 ENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKI 614
E + L L +A+ + +IA+ Q+ + + +++ K+
Sbjct: 1892 EEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKV 1937
Score = 61.2 bits (147), Expect = 3e-09
Identities = 95/483 (19%), Positives = 194/483 (40%), Gaps = 57/483 (11%)
Query: 181 RKQKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPAN 240
+++ ++ +E E + L++A ++ +K E K D++ + L H
Sbjct: 1140 KQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLR 1199
Query: 241 KKLSTTLPEIE------YREKGK-EKDKDAKKHNLGINNNNI-------------LQPVD 280
KK + ++ E+ R K K EK+K K + +N+ + ++
Sbjct: 1200 KKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLE 1259
Query: 281 SKIQEIEYMENHINSKRLNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATN 340
++ E++ E +RL NDL L E + + K A +V+ R A
Sbjct: 1260 DQLSELKSKEEE--QQRLINDLTAQRGRLQTESGEFSRQLDEKEA--LVSQLSRGKQAFT 1315
Query: 341 GSIPSSSSKNEKKQKCTSKSPSTHK--------DLMENCIPNNQLSKPD---ALVRLEQD 389
I K + +++ +K+ H DL+ Q SK + AL + +
Sbjct: 1316 QQI--EELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTE 1373
Query: 390 IKKLKAD-----LQASRQVEQELRSQISSLSSTER---GIRSEMGQLRQENELLQNKLHN 441
+ + + +Q + ++E+ + L + E + ++ L + + LQN++ +
Sbjct: 1374 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVED 1433
Query: 442 AVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGE 501
+ ++ + L+KK + + + KQ EE + AR++
Sbjct: 1434 LMLDVERTNAACAALDKKQRNFDKILA-EWKQKCEETHAELEASQKEARSLGTELFKIKN 1492
Query: 502 CTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKEN-EKDTEVLMSALSA 560
E +++ L+ E K L ++ +QI E ++ EL K K+ E++ L +AL
Sbjct: 1493 AYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEE 1552
Query: 561 MQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAEVMAV 620
+ +H E + RI+L+L + R+ I +KD+EI LK+ ++
Sbjct: 1553 AEASLEHEEGKI---LRIQLELNQVKSEVDRK-------IAEKDEEIDQLKRNHIRIVES 1602
Query: 621 MPS 623
M S
Sbjct: 1603 MQS 1605
Score = 59.3 bits (142), Expect = 1e-08
Identities = 85/428 (19%), Positives = 168/428 (39%), Gaps = 81/428 (18%)
Query: 279 VDSKIQEIEYMENHINSKRLNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSA 338
+++KI+E+ E + + +N +L L ED C+ K+ + + + A
Sbjct: 921 LEAKIKEVT--ERAEDEEEINAELTAKKRKL--EDECSELKKDIDDLELTLAKVEKEKHA 976
Query: 339 TNGSIPSSSSK-----------NEKKQKCTSKSPSTHKDLMENCIPNNQLSKPDALVRLE 387
T + + + + ++K+ T DL N L+K A ++LE
Sbjct: 977 TENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTK--AKIKLE 1034
Query: 388 QDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNA----- 442
Q + L+ L+ +++ +L L + + + + E + L KL
Sbjct: 1035 QQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEIS 1094
Query: 443 -VQMKQKDKQNIS-QLEKKLK--------------AEQEARSFVEKQLME---------- 476
+Q K +D+Q + QL+KK+K AE+ +R+ EKQ +
Sbjct: 1095 NLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISE 1154
Query: 477 -----------------------EKKRKKLEEATAARAVAFAAASR--GECTETLRNRIR 511
+K R+ LEEAT A + + L +I
Sbjct: 1155 RLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQID 1214
Query: 512 ELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKEN-EKDTEVLMSALSAMQDKTQHLEN 570
L+ +KL + + +I +L V+ + K K N EK L LS ++ K + +
Sbjct: 1215 NLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQR 1274
Query: 571 SLSAETRIKLDLFSALGDAKRQLEIAQGQILQKD-------QEIKDLKQKIAEVMAVMPS 623
++ T + L + G+ RQL+ + + Q Q+I++LK+++ E + +
Sbjct: 1275 LINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNA 1334
Query: 624 ITYSAATS 631
+ ++ +S
Sbjct: 1335 LAHALQSS 1342
Score = 52.4 bits (124), Expect = 1e-06
Identities = 56/253 (22%), Positives = 116/253 (45%), Gaps = 21/253 (8%)
Query: 383 LVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNA 442
L +Q ++ A+L+AS++ + L +++ + + ++ L++EN+ LQ ++ +
Sbjct: 1459 LAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDL 1518
Query: 443 VQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAAR----------AV 492
+ + + I +LEK K ++ + ++ L E + + EE R V
Sbjct: 1519 TEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEV 1578
Query: 493 AFAAASRGECTETL-RNRIRELEAEGKKLTMDMKVKEDQIR-----ELELKVQELRKYKE 546
A + E + L RN IR +E+ L +++ + D IR E +L E++
Sbjct: 1579 DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHA 1638
Query: 547 NEKDTEVL---MSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQK 603
N E L + ++D HL+++L ++ +K L A+ + + L A+ + L+
Sbjct: 1639 NRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQL--AMVERRANLLQAEIEELRA 1696
Query: 604 DQEIKDLKQKIAE 616
E + +KIAE
Sbjct: 1697 TLEQTERSRKIAE 1709
Score = 51.6 bits (122), Expect = 2e-06
Identities = 52/239 (21%), Positives = 105/239 (43%), Gaps = 14/239 (5%)
Query: 383 LVRLEQDIKKLKADLQASRQVEQELRSQISSL----SSTERGIRSEMGQLRQENELLQNK 438
+ ++++ +K+K +L S +EL ++ +L + + +++E L E
Sbjct: 855 MATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQL 914
Query: 439 LHNAVQMKQKDKQNISQLE--KKLKAEQEARSF-VEKQLMEEKKRKKLEEATAARAVAFA 495
+ +Q++ K K+ + E +++ AE A+ +E + E KK E T A+
Sbjct: 915 IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 974
Query: 496 AASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKENEKDTEVLM 555
A+ + + L + L+ KLT + K + E Q L + E L
Sbjct: 975 HATENK-VKNLTEEMAGLDETIAKLTKEKKALQ------EAHQQTLDDLQAEEDKVNTLT 1027
Query: 556 SALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKI 614
A ++ + LE SL E ++++DL A + L++AQ I+ + E + L +K+
Sbjct: 1028 KAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKL 1086
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 65.9 bits (159), Expect = 1e-10
Identities = 102/476 (21%), Positives = 191/476 (40%), Gaps = 79/476 (16%)
Query: 185 EVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKKLS 244
E K+ EF + LQ + EQ + + +K+ +E + +++ I A K+ S
Sbjct: 1084 EKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1143
Query: 245 TTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNNDLVG 304
E+E + E+ A + +N K +E E+ +++ DL
Sbjct: 1144 DLSRELEEISERLEEAGGATSAQIEMN----------KKREAEF-------QKMRRDL-- 1184
Query: 305 STENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPSTH 364
E + TA++ K+A V + I + +K +K S+
Sbjct: 1185 --EEATLQHEATAATLRKKHADSVAELGEQ--------IDNLQRVKQKLEKEKSEMKMEI 1234
Query: 365 KDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSE 424
DL N +SK A LE+ + L+ L + E+E + I+ L++ +++E
Sbjct: 1235 DDLASNV---ETVSK--AKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTE 1289
Query: 425 MGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKK----- 479
G+ ++ + + + + KQ Q I +L+++L+ E +A++ + L +
Sbjct: 1290 SGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLL 1349
Query: 480 RKKLEEATAARAVAFAAASRGECTETLR----------NRIRELEAEGKKLTMDMKVKED 529
R++ EE ++A A S+ TE + R ELE KKL ++ E+
Sbjct: 1350 REQYEEEQESKAELQRALSKAN-TEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEE 1408
Query: 530 QIRELELKVQELRKYKEN-EKDTEVLM------SALSAMQDKTQHLENSLSAETRIKLD- 581
+ + K L K K+ + + E LM +A A DK Q + + AE + K +
Sbjct: 1409 HVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEE 1468
Query: 582 ---------------------LFSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAE 616
+ +A ++ QLE + + QEI DL ++IAE
Sbjct: 1469 THAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAE 1524
Score = 63.5 bits (153), Expect = 6e-10
Identities = 92/466 (19%), Positives = 202/466 (43%), Gaps = 37/466 (7%)
Query: 170 FKSYVSYKMRLRKQKEVQKENEFYMQLLQQALPP---------EQQMLQKQ-EKEAEEAA 219
FK +Y+ L + + +++EN+ Q + E + ++KQ E+E E
Sbjct: 1488 FKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQ 1547
Query: 220 KGLPDMDSSILIHHNGGIPANKKLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPV 279
L + ++S L H G I ++ L +++ K +KD + L N+ I++ +
Sbjct: 1548 AALEEAEAS-LEHEEGKI---LRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESM 1603
Query: 280 DSKIQ-EIEYMENHIN-SKRLNNDLVGSTENLLKEDSCTASS-KNYKNASGVVNSSPRSH 336
S + EI + I K++ DL L + A + +NY+N G++ +
Sbjct: 1604 QSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDT---Q 1660
Query: 337 SATNGSIPSSSSKNEKKQKCTSKSPSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKAD 396
+ ++ S E+ ++ ++ E Q + + EQ++
Sbjct: 1661 IHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIA--EQEL------ 1712
Query: 397 LQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQL 456
L AS +V Q L +Q +SL +T++ + +++ Q++ E E + + NA + +K + + +
Sbjct: 1713 LDASERV-QLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMM 1771
Query: 457 EKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAE 516
++LK EQ+ + +E+ ++ K + A A + + L R+RELE E
Sbjct: 1772 AEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGE 1831
Query: 517 -------GKKLTMDMKVKEDQIRELELKVQELRKYKENEKD-TEVLMSALSAMQDKTQHL 568
+ ++ E +++EL + +E RK +D + L + + + + + +
Sbjct: 1832 VESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEA 1891
Query: 569 ENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKI 614
E + L L +A+ + +IA+ Q+ + + +++ K+
Sbjct: 1892 EEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKV 1937
Score = 61.2 bits (147), Expect = 3e-09
Identities = 95/483 (19%), Positives = 194/483 (40%), Gaps = 57/483 (11%)
Query: 181 RKQKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPAN 240
+++ ++ +E E + L++A ++ +K E K D++ + L H
Sbjct: 1140 KQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLR 1199
Query: 241 KKLSTTLPEIE------YREKGK-EKDKDAKKHNLGINNNNI-------------LQPVD 280
KK + ++ E+ R K K EK+K K + +N+ + ++
Sbjct: 1200 KKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLE 1259
Query: 281 SKIQEIEYMENHINSKRLNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATN 340
++ E++ E +RL NDL L E + + K A +V+ R A
Sbjct: 1260 DQLSELKSKEEE--QQRLINDLTAQRGRLQTESGEFSRQLDEKEA--LVSQLSRGKQAFT 1315
Query: 341 GSIPSSSSKNEKKQKCTSKSPSTHK--------DLMENCIPNNQLSKPD---ALVRLEQD 389
I K + +++ +K+ H DL+ Q SK + AL + +
Sbjct: 1316 QQI--EELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTE 1373
Query: 390 IKKLKAD-----LQASRQVEQELRSQISSLSSTER---GIRSEMGQLRQENELLQNKLHN 441
+ + + +Q + ++E+ + L + E + ++ L + + LQN++ +
Sbjct: 1374 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVED 1433
Query: 442 AVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGE 501
+ ++ + L+KK + + + KQ EE + AR++
Sbjct: 1434 LMLDVERTNAACAALDKKQRNFDKILA-EWKQKCEETHAELEASQKEARSLGTELFKIKN 1492
Query: 502 CTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKEN-EKDTEVLMSALSA 560
E +++ L+ E K L ++ +QI E ++ EL K K+ E++ L +AL
Sbjct: 1493 AYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEE 1552
Query: 561 MQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAEVMAV 620
+ +H E + RI+L+L + R+ I +KD+EI LK+ ++
Sbjct: 1553 AEASLEHEEGKI---LRIQLELNQVKSEVDRK-------IAEKDEEIDQLKRNHIRIVES 1602
Query: 621 MPS 623
M S
Sbjct: 1603 MQS 1605
Score = 59.3 bits (142), Expect = 1e-08
Identities = 85/428 (19%), Positives = 168/428 (39%), Gaps = 81/428 (18%)
Query: 279 VDSKIQEIEYMENHINSKRLNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSA 338
+++KI+E+ E + + +N +L L ED C+ K+ + + + A
Sbjct: 921 LEAKIKEVT--ERAEDEEEINAELTAKKRKL--EDECSELKKDIDDLELTLAKVEKEKHA 976
Query: 339 TNGSIPSSSSK-----------NEKKQKCTSKSPSTHKDLMENCIPNNQLSKPDALVRLE 387
T + + + + ++K+ T DL N L+K A ++LE
Sbjct: 977 TENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTK--AKIKLE 1034
Query: 388 QDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNA----- 442
Q + L+ L+ +++ +L L + + + + E + L KL
Sbjct: 1035 QQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEIS 1094
Query: 443 -VQMKQKDKQNIS-QLEKKLK--------------AEQEARSFVEKQLME---------- 476
+Q K +D+Q + QL+KK+K AE+ +R+ EKQ +
Sbjct: 1095 NLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISE 1154
Query: 477 -----------------------EKKRKKLEEATAARAVAFAAASR--GECTETLRNRIR 511
+K R+ LEEAT A + + L +I
Sbjct: 1155 RLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQID 1214
Query: 512 ELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKEN-EKDTEVLMSALSAMQDKTQHLEN 570
L+ +KL + + +I +L V+ + K K N EK L LS ++ K + +
Sbjct: 1215 NLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQR 1274
Query: 571 SLSAETRIKLDLFSALGDAKRQLEIAQGQILQKD-------QEIKDLKQKIAEVMAVMPS 623
++ T + L + G+ RQL+ + + Q Q+I++LK+++ E + +
Sbjct: 1275 LINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNA 1334
Query: 624 ITYSAATS 631
+ ++ +S
Sbjct: 1335 LAHALQSS 1342
Score = 52.4 bits (124), Expect = 1e-06
Identities = 56/253 (22%), Positives = 116/253 (45%), Gaps = 21/253 (8%)
Query: 383 LVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNA 442
L +Q ++ A+L+AS++ + L +++ + + ++ L++EN+ LQ ++ +
Sbjct: 1459 LAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDL 1518
Query: 443 VQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAAR----------AV 492
+ + + I +LEK K ++ + ++ L E + + EE R V
Sbjct: 1519 TEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEV 1578
Query: 493 AFAAASRGECTETL-RNRIRELEAEGKKLTMDMKVKEDQIR-----ELELKVQELRKYKE 546
A + E + L RN IR +E+ L +++ + D IR E +L E++
Sbjct: 1579 DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHA 1638
Query: 547 NEKDTEVL---MSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQK 603
N E L + ++D HL+++L ++ +K L A+ + + L A+ + L+
Sbjct: 1639 NRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQL--AMVERRANLLQAEIEELRA 1696
Query: 604 DQEIKDLKQKIAE 616
E + +KIAE
Sbjct: 1697 TLEQTERSRKIAE 1709
Score = 51.6 bits (122), Expect = 2e-06
Identities = 52/239 (21%), Positives = 105/239 (43%), Gaps = 14/239 (5%)
Query: 383 LVRLEQDIKKLKADLQASRQVEQELRSQISSL----SSTERGIRSEMGQLRQENELLQNK 438
+ ++++ +K+K +L S +EL ++ +L + + +++E L E
Sbjct: 855 MATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQL 914
Query: 439 LHNAVQMKQKDKQNISQLE--KKLKAEQEARSF-VEKQLMEEKKRKKLEEATAARAVAFA 495
+ +Q++ K K+ + E +++ AE A+ +E + E KK E T A+
Sbjct: 915 IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 974
Query: 496 AASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKENEKDTEVLM 555
A+ + + L + L+ KLT + K + E Q L + E L
Sbjct: 975 HATENK-VKNLTEEMAGLDETIAKLTKEKKALQ------EAHQQTLDDLQAEEDKVNTLT 1027
Query: 556 SALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKI 614
A ++ + LE SL E ++++DL A + L++AQ I+ + E + L +K+
Sbjct: 1028 KAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKL 1086
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 65.9 bits (159), Expect = 1e-10
Identities = 91/469 (19%), Positives = 191/469 (40%), Gaps = 43/469 (9%)
Query: 179 RLRKQKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIH-HNGGI 237
+LR + +KE E +Q +Q + ++ ++K K ++ L + + + H G
Sbjct: 1649 KLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGD 1708
Query: 238 PANKKLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKR 297
A + + T L ++ E+ K + L +++ DS +E++ +++ I
Sbjct: 1709 TAKECMETLLSSNASMKEELERVK-MEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNV 1767
Query: 298 LNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCT 357
+ +TE K D+ T ++ + + + S + + P+ S E
Sbjct: 1768 SKQANLEATE---KHDNQTNVTE--EGTQSIPGETEEQDSLSMSTRPTCS---ESVPSAK 1819
Query: 358 SKSPSTHKDLMENCIPNNQLSKPDALVR----LEQDIKKLKADLQASRQVEQELRSQISS 413
S +P+ KD + NN L + D L LE++ +K K Q + L SQIS+
Sbjct: 1820 SANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQIST 1879
Query: 414 LSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKL-----KAEQEARS 468
+ ++ E+ ++ N+ +Q +L ++K+ ++ LE++L + +
Sbjct: 1880 KDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGN 1939
Query: 469 FVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKE 528
+ + + K + LE + L+ + ELE E ++L + E
Sbjct: 1940 YCQDVTDAQIKNELLESE----------------MKNLKKCVSELEEEKQQLVKEKTKVE 1983
Query: 529 DQIRELEL-KVQELRKYKENEKDTEVLMSALSAMQDKTQHL-------ENSLSAETRIKL 580
+IR+ L K+Q +K N+ + L L Q + + L + +SA R
Sbjct: 1984 SEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2043
Query: 581 DLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAEVMAVMPSITYSAA 629
L ++++ LEI + + Q + K + ++A ++ AA
Sbjct: 2044 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAA 2092
Score = 62.4 bits (150), Expect = 1e-09
Identities = 71/386 (18%), Positives = 176/386 (45%), Gaps = 41/386 (10%)
Query: 255 KGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNNDLVGSTENLLKEDS 314
K + K+ +A+K L + ++ + K +E+ ++ IN + L + S + + E
Sbjct: 1308 KAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLE---IESLKTVSHEAE 1364
Query: 315 CTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPS---------THK 365
A S K S + + H + K ++ QK SK + K
Sbjct: 1365 VHAESLQQKLESSQLQIAGLEH------LRELQPKLDELQKLISKKEEDVSYLSGQLSEK 1418
Query: 366 DLMENCIPNNQLSKPDALVRL-----------EQDIKKLKADLQASRQVEQELRSQISSL 414
+ I + + D + L ++ IK+L+ +L +Q +E+ + +
Sbjct: 1419 EAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAK 1478
Query: 415 SSTERGIRSEMGQLRQ---ENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFV- 470
+R +++ + ++ EN+ LQ +L A ++ ++++ +E ++ A+ + + V
Sbjct: 1479 QQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVL 1538
Query: 471 -EKQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMK-VKE 528
L++E++ K + E R++ + C E+L+ + L + +KL +++ +K
Sbjct: 1539 GRLALLQEERDKLITEMD--RSLLENQSLSSSC-ESLKLALEGLTEDKEKLVKEIESLKS 1595
Query: 529 DQIRELELKVQELRKYKENEKDTEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGD 588
+I E + K+KE +K+ E+L+ + + ++ + +++ + A + K +L+ L
Sbjct: 1596 SKIAE---STEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRS 1652
Query: 589 AKRQLEIAQGQILQKDQEIKDLKQKI 614
+ + + Q+ + +QE++++K+K+
Sbjct: 1653 TEANKKETEKQLQEAEQEMEEMKEKM 1678
Score = 53.5 bits (127), Expect = 6e-07
Identities = 100/510 (19%), Positives = 216/510 (42%), Gaps = 56/510 (10%)
Query: 179 RLRKQKEVQKENEFYMQLLQQALPPEQQML-----QKQEKEAEEAAKGLPDMDSSILIHH 233
+L K + E E ++ ++ L +++++ Q + +AE+ A+ +M+ +++
Sbjct: 131 QLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQ 190
Query: 234 NGGIPANKKLSTTLP------EIEYREKGKEKDKDAK-KHNLGINNNNILQPVDSKIQEI 286
+ ++ +TL + E + ++KDA+ + + ++ + +LQ V E
Sbjct: 191 Q--LQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDELLQLVTQADVET 248
Query: 287 EYMEN-HINSKRLNN---DLVGSTENL-LKEDSCTASSKNYKNASGVVNSSPRSHSATNG 341
E + + ++L LVG + + L + TA+ + + S + H+
Sbjct: 249 EMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRN 308
Query: 342 SIPSSSSKN----EKKQKCTSKSPSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADL 397
++ + ++ EK + ++ + +L E ++ L + + + + +++ + L
Sbjct: 309 TVETEREESKILLEKMELEVAERKLSFHNLQEEM--HHLLEQFEQAGQAQAELESRYSAL 366
Query: 398 QASRQVEQELR-SQISSLSSTERGIRSEMGQLRQEN-ELLQNKLHNAVQMKQKDKQNISQ 455
+ + E E + S I SL T + ++S L+ +N +LLQ+K AVQ Q +Q Q
Sbjct: 367 EQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQ 426
Query: 456 LEKKLKAEQEARSFVEKQLMEEKKRKKL----EEATAARAVAFAAASRGECTETLRNR-- 509
L++K K + + + Q E + E T A A+ + E +
Sbjct: 427 LQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGA 486
Query: 510 -------IRELEAEGKKLTMDMKVKEDQIR--ELELKVQELRKYKENEKDTEVLMSALSA 560
+ EL+AE +KL+ + + E Q R E + +V E+ K + SA
Sbjct: 487 LLLSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEISIVDIANKRSS------SA 540
Query: 561 MQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQK-----DQEI---KDLKQ 612
+ LEN+ S + + L + +A+ ++ + Q+ K D E+ K++KQ
Sbjct: 541 EESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQ 600
Query: 613 KIAEVMAVMPSITYSAATSPLSPVSPHYSS 642
E +A + + T P+ P+ S
Sbjct: 601 MEGEGIAPIKMKVFLEDTGQDFPLMPNEES 630
Score = 52.8 bits (125), Expect = 1e-06
Identities = 85/419 (20%), Positives = 165/419 (39%), Gaps = 70/419 (16%)
Query: 180 LRKQKEVQ-KENEFYMQLLQQALPPEQQMLQKQEKEAEE--AAKGLPDMDSSILIHHNGG 236
L Q E+Q KE++ ++ LQ L +M QK E+ EE A + + + LI
Sbjct: 1439 LHTQLEMQAKEHDERIKQLQVELC---EMKQKPEEIGEESRAKQQIQRKLQAALISRKEA 1495
Query: 237 IPANK--------------KLSTTLPEIEYREKGKEKDKDAKKHNLGI---NNNNILQPV 279
+ NK +L+ +L ++E + + K+KD L + + ++ +
Sbjct: 1496 LKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEM 1555
Query: 280 DSKIQEIEYMENHINSKRLNND-LVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSA 338
D + E + + + S +L + L E L+KE SSK
Sbjct: 1556 DRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSK------------------ 1597
Query: 339 TNGSIPSSSSKNEKKQKCTSKSPSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQ 398
I S+ EK HK+L + Q + + + ++++ ++
Sbjct: 1598 ----IAESTEWQEK-----------HKELQKEYEILLQ-----SYENVSNEAERIQHVVE 1637
Query: 399 ASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEK 458
A RQ +QEL ++ S + ++ ++ + QE E ++ K+ + KQ+ + +
Sbjct: 1638 AVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEEND 1697
Query: 459 KLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGK 518
+L+AE K+ ME V ETL + + L +E
Sbjct: 1698 RLRAEVHPAGDTAKECMETLLSSNASMKEELERVKME-------YETLSKKFQSLMSEKD 1750
Query: 519 KLTMDMKVKEDQIRELELKVQELRKYKENEKDTEVLMSALSAMQDKTQHLENSLSAETR 577
L+ +++ + QI K L ++++ T V ++ +T+ ++SLS TR
Sbjct: 1751 SLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEE-QDSLSMSTR 1808
Score = 52.4 bits (124), Expect = 1e-06
Identities = 120/548 (21%), Positives = 210/548 (38%), Gaps = 147/548 (26%)
Query: 197 LQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKKLSTTLPE-----IE 251
L++ + Q L K++KE ++ + L DS++ + A K ++L + I+
Sbjct: 2155 LEETIGEIQVTLNKKDKEVQQLQENL---DSTVT-----QLAAFTKSMSSLQDDRDRVID 2206
Query: 252 YREKGKEKDKDA---KKHNLGINNNNILQPVDSKIQEIEYMEN-HINSKRLNNDLV---- 303
+K + K DA K+ + + +N D Q +ME IN RL +D
Sbjct: 2207 EAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWES 2266
Query: 304 -GSTENLLKEDSC-TASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSP 361
TE L++ C T +N + S + + HS+ N S K + T S
Sbjct: 2267 KAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSN 2326
Query: 362 STHKDLMENCIPNNQLSKPDALVRLEQ--------DIKKLKADLQASRQVEQELRSQI-- 411
S +E C Q + ++R ++ ++L+ DLQASR++ L +I
Sbjct: 2327 S-----LEKC--KEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINM 2379
Query: 412 ------SSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQE 465
S LS E I+ + +LRQ+++ + I +LE L E+E
Sbjct: 2380 KEQKIISLLSGKEEAIQVAIAELRQQHD-----------------KEIKELENLLSQEEE 2422
Query: 466 ARSFVEK----------QLMEEKKR---------------------------------KK 482
+E+ QLME K ++
Sbjct: 2423 ENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQ 2482
Query: 483 LEEATAA------RAVAFAAASRGECTET---LRNRIRELEAEGKKLTMD---------- 523
LEE + + + AAA + E LR+ + +L +E KL +
Sbjct: 2483 LEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQ 2542
Query: 524 ------------MKVKEDQIRELELKVQEL-RKYKENEKDTEVLMSALSAMQDKTQHLEN 570
++V+ Q +ELE K +L K KE+E+ E L + +A+Q++ Q L
Sbjct: 2543 VITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSK 2602
Query: 571 -------SLSAETR--IKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAEVMAVM 621
S+S TR L LG QL++ + ++ + +++IAE+ +
Sbjct: 2603 EIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEEL 2662
Query: 622 PSITYSAA 629
+ AA
Sbjct: 2663 VCVQKEAA 2670
Score = 49.7 bits (117), Expect = 9e-06
Identities = 100/485 (20%), Positives = 192/485 (39%), Gaps = 91/485 (18%)
Query: 186 VQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKKLST 245
++KENE + LQ AL +++LQ+ + EE A + K
Sbjct: 984 LKKENEQRKRKLQAALINRKELLQRVSRLEEELA----------------NLKDESKKEI 1027
Query: 246 TLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIE-YMENHINSK-----RLN 299
L E E E E+DK+ K+++ + V SK QEIE Y++ I+ K +
Sbjct: 1028 PLSETERGE--VEEDKENKEYS--------EKCVTSKCQEIEIYLKQTISEKEVELQHIR 1077
Query: 300 NDLVGST------ENLLKEDSCTASSKN----------YKNASGVVNSSPRSHSATNG-S 342
DL + L+K+ + T K +N + + + A++G S
Sbjct: 1078 KDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDS 1137
Query: 343 IPSSSSKNEKKQKCTSKSPSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQ 402
+ CT S +L E + + K +L++ + KA L+ +++
Sbjct: 1138 VALVKETVVISPPCTGSSEHWKPELEEKILALEK-EKEQLQKKLQEALTSRKAILKKAQE 1196
Query: 403 VEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKA 462
E+ LR ++ ++ + + +ENE + + Q++Q Q ++ KL +
Sbjct: 1197 KERHLREELKQQKDDYNRLQEQFDEQSKENENIGD------QLRQLQIQVRESIDGKLPS 1250
Query: 463 EQEARSFVEKQLMEEKKRKKLEEATA-------------ARAVAFAAASRGECTETLRNR 509
+ S +EE K E+ + + +A G ++ +
Sbjct: 1251 TDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQ 1310
Query: 510 IRELEAEGKKLTMDMKVK----------------EDQIRELELKVQELRKYK-ENEKDTE 552
++E+EAE K+ +++KV ++QI + L+++ L+ E E E
Sbjct: 1311 LKEIEAE--KVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAE 1368
Query: 553 VLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQ-LEIAQGQILQKDQEIKDLK 611
L L + Q + LE+ E + KLD L K + + GQ+ +K+ + ++
Sbjct: 1369 SLQQKLESSQLQIAGLEH--LRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQ 1426
Query: 612 QKIAE 616
+I E
Sbjct: 1427 TEIIE 1431
Score = 47.4 bits (111), Expect = 4e-05
Identities = 56/241 (23%), Positives = 102/241 (42%), Gaps = 39/241 (16%)
Query: 402 QVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLK 461
Q+ QE ++ + L RG+RS M L EN L +L +Q ++ Q I+ + + K
Sbjct: 2496 QLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAEL---IQYREDLNQVITIKDSQQK 2552
Query: 462 AEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLT 521
E + K+L E K KLEE E E LR L+ E + L+
Sbjct: 2553 QLLEVQLQQNKEL--ENKYAKLEE---------KLKESEEANEDLRRSFNALQEEKQDLS 2601
Query: 522 MDMKVKEDQIRELELKVQELR----------KYKENEKDTEVLMSALSAMQDKTQHLENS 571
+++ + I +L +V L+ + K E++ L + S+ Q + LE
Sbjct: 2602 KEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEE 2661
Query: 572 L------------SAETRIKLDLFSALGDA---KRQLEIAQGQILQKDQEIKDLKQKIAE 616
L E ++K +L DA + + E A+ ++ + +++ +++QK+
Sbjct: 2662 LVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLM 2721
Query: 617 V 617
V
Sbjct: 2722 V 2722
Score = 43.1 bits (100), Expect = 8e-04
Identities = 84/469 (17%), Positives = 187/469 (39%), Gaps = 66/469 (14%)
Query: 177 KMRLRKQKEVQKE--NEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHN 234
K L K + QKE N+ + + LQ+ L +QQ +++ +K+ + + ++ ++
Sbjct: 1988 KEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEF 2047
Query: 235 GGIPANKKLSTTLPE----IEYREKGKEK---------DKDAKKHNLGINNNNILQPVDS 281
+ K L T +E+R+K + + D ++ + +N + + + S
Sbjct: 2048 VQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQS 2107
Query: 282 KIQEIEYMENHINSKRLNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNG 341
+ ++ + L L + E LKE KN + + T G
Sbjct: 2108 NKESVKSQMKQ-KDEDLERRLEQAEEKHLKE------KKNMQEKLDALRREKVHLEETIG 2160
Query: 342 SIPSSSSKNEKK-QKCTSKSPSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQAS 400
I + +K +K+ Q+ ST L + S D R+ + KK + +
Sbjct: 2161 EIQVTLNKKDKEVQQLQENLDSTVTQLA--AFTKSMSSLQDDRDRVIDEAKKWERKFSDA 2218
Query: 401 RQVEQE-----------LRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKD 449
Q ++E L+ Q+ +S ++ + +L + ++ ++K VQ++QK
Sbjct: 2219 IQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKV 2278
Query: 450 KQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRNR 509
+ K+L ++ E + E + + E ++L+++
Sbjct: 2279 CDTLQGENKELLSQLEETRHLYHSSQNELAKLESE------------------LKSLKDQ 2320
Query: 510 IRELEAEGKKLTMDMKVKEDQIRELELKVQELR-KYKENEKDTEVLMSALSAMQDKTQHL 568
+ +L +K E IR+ E +Q + Y++ E D L A ++ T L
Sbjct: 2321 LTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETD-------LQASRELTSRL 2373
Query: 569 ENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQK-DQEIKDLKQKIAE 616
++ + + + S L + +++A ++ Q+ D+EIK+L+ +++
Sbjct: 2374 HEEINMKEQ---KIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQ 2419
Score = 38.9 bits (89), Expect = 0.015
Identities = 67/362 (18%), Positives = 136/362 (37%), Gaps = 44/362 (12%)
Query: 212 EKEAEEAAKGLPDMDSSILI--HHNGGIPAN-KKLSTTLPEIEYREKGKEKDKDAKKHNL 268
E+ E A+ L +M+ +L+ N G+ A + ++ ++ ++ D K
Sbjct: 2702 EERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKY 2761
Query: 269 GINNNNILQ---------PVDSKIQEIEYMENHINS------KRLNNDLVGSTENLLKED 313
+ + Q D+ + E + N ++LN L+ E LL
Sbjct: 2762 DASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLS 2821
Query: 314 SCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPSTHKDLMENCIP 373
S S N + +S ++ + K+E+ ++ ++ PST P
Sbjct: 2822 SQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTS--------P 2873
Query: 374 NNQLSKPDALVRLEQD----IKKLKADLQASRQVEQE------LRSQISSLSSTERGIRS 423
S A+ L+ D +K+LK Q Q+ QE L++Q+ + +
Sbjct: 2874 AEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQI 2933
Query: 424 EMGQLRQENELLQNKLHNAVQMKQK----DKQNISQLEKKLKAEQEARSFVEKQLMEEKK 479
+LRQEN Q++LH K +++ Q + + + S ++ + E +
Sbjct: 2934 MQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQQLSHLQNLIRELRS 2993
Query: 480 RKKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQ 539
+ + A+ + +N + E E +L +K +I + EL++Q
Sbjct: 2994 SSSQTQPLKVQYQRQASPETSASPDGSQNLVYETELLRTQLNDSLK----EIHQKELRIQ 3049
Query: 540 EL 541
+L
Sbjct: 3050 QL 3051
Score = 37.7 bits (86), Expect = 0.034
Identities = 45/212 (21%), Positives = 86/212 (40%), Gaps = 41/212 (19%)
Query: 390 IKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQ-LRQENELLQNKLHNAVQMKQK 448
++ L +L++S Q L+ Q +S E + Q L E ELL+ +L+++++ +
Sbjct: 2984 LQNLIRELRSSSSQTQPLKVQYQRQASPETSASPDGSQNLVYETELLRTQLNDSLKEIHQ 3043
Query: 449 DKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTE---T 505
+ I QL QL+EEK ++ ++++ G+
Sbjct: 3044 KELRIQQLNSNFS-----------QLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHCAV 3092
Query: 506 LRNRIRELEA-------------------------EGKKLTMDMKVKEDQIRELELKVQE 540
L +++EL+A E ++ + Q+ +V E
Sbjct: 3093 LEKQVQELQAGPLNIDVAPGAPQEKNGVHRKSDPEELREPQQSFSEAQQQLCNTRQEVNE 3152
Query: 541 LRKYKENEKDTEVLM-SALSAMQDKTQHLENS 571
LRK E E+D V +ALS +++ + LE+S
Sbjct: 3153 LRKLLEEERDQRVAAENALSVAEEQIRRLEHS 3184
Score = 33.5 bits (75), Expect = 0.65
Identities = 52/241 (21%), Positives = 100/241 (41%), Gaps = 43/241 (17%)
Query: 386 LEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQM 445
LE + +L +E + +I+ L +G R+E ++E+L K +M
Sbjct: 548 LENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAE----EADHEVLDQK-----EM 598
Query: 446 KQKDKQNISQLEKKLKAEQEARSF------------VEKQLMEEKKRKKLEEATAARAVA 493
KQ + + I+ ++ K+ E + F VEK+ + + + E +
Sbjct: 599 KQMEGEGIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEISLNDAG 658
Query: 494 FAAASR--------------GEC----TETLRNRIRELEAEGKKLT-MDMKVKEDQIREL 534
S G+C E L+++I ELE K + K +++ +E+
Sbjct: 659 VELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEI 718
Query: 535 ELKVQELRKYKENEKDTEVLMSALSAMQDK--TQHLENSLSAETRIKL-DLFSALGDAKR 591
Q + ++K+N + +ALS +D+ +Q E S+ E R ++ L L +A+R
Sbjct: 719 SNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAER 778
Query: 592 Q 592
Q
Sbjct: 779 Q 779
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 65.5 bits (158), Expect = 2e-10
Identities = 96/460 (20%), Positives = 189/460 (41%), Gaps = 70/460 (15%)
Query: 183 QKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKK 242
Q+E +++ +L Q L E+ LQ Q E EA + L S++ I + + KK
Sbjct: 1325 QEETRQKLNVSTKLRQ--LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSD---SKKK 1379
Query: 243 LSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNNDL 302
L +E E+GK++ + +EIE + K D
Sbjct: 1380 LQDFASTVEALEEGKKRFQ----------------------KEIENLTQQYEEKAAAYDK 1417
Query: 303 VGSTENLLKE--DSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKS 360
+ T+N L++ D N + + R + SSK ++ +++
Sbjct: 1418 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERD-RAEA 1476
Query: 361 PSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERG 420
+ K+ + +A LE+ K LKA+++ + ++ + L ++R
Sbjct: 1477 EAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRA 1536
Query: 421 IRSEMGQLRQENELLQNKLHNAVQMKQKDKQNI----SQLEKKLKAEQEARSFVEKQLME 476
+ ++M +++ + E L+++L K + + N+ Q E+ L+A E +QL
Sbjct: 1537 LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQR 1596
Query: 477 E--KKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIREL 534
+ + +LE+ RA+A AA + L +++LE + + Q+R+L
Sbjct: 1597 QLHEYETELEDERKQRALAAAAKKK------LEGDLKDLELQADSAIKGREEAIKQLRKL 1650
Query: 535 ELKVQELRK---------------YKENEKDTEVLMSALSAMQD---------KTQHLE- 569
+ ++++ ++ KENEK + L + L +Q+ K LE
Sbjct: 1651 QAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEK 1710
Query: 570 NSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKD 609
L+ E L +AL D KR+LE +I Q ++E+++
Sbjct: 1711 EELAEELASSLSGRNALQDEKRRLE---ARIAQLEEELEE 1747
Score = 57.8 bits (138), Expect = 3e-08
Identities = 102/491 (20%), Positives = 212/491 (43%), Gaps = 63/491 (12%)
Query: 180 LRKQKEVQKENEFYMQLLQQA---LPPEQQMLQKQEK-------EAEE-----AAKG--- 221
L+K KE Q++ E ++ L+Q L E+ +LQ+Q + EAEE AAK
Sbjct: 861 LQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQEL 920
Query: 222 ---LPDMDSSILIHHNGGIPAN---KKLSTTLPEIEYREKGKEKDKDAKKHNLG-INNNN 274
L +M++ + + G KK++ + ++E E+ +E++ +K L +
Sbjct: 921 EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLE--EQLEEEEAARQKLQLEKVTAEA 978
Query: 275 ILQPVDSKIQEIEYMENHINSKR--LNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSS 332
++ ++ +I ++ N ++ +R L + T NL +E+ + KN + + N
Sbjct: 979 KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE------EKAKNLTKLKNKH 1032
Query: 333 PRSHSATNGSIPSSSSKNEKKQKCTSKSPSTHKDLMENCIP--------NNQLSKPD--- 381
S + ++ +K K D E QL+K +
Sbjct: 1033 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1092
Query: 382 --ALVRLEQDIKKLKADLQASRQVE---QELRSQISSLSSTERGIRSEMGQLRQENELLQ 436
AL RL+ +I + L+ R++E +L+ + S + + L +E E L+
Sbjct: 1093 QAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALK 1152
Query: 437 NKLHNAV-------QMKQKDKQNISQLEKKLKAEQEARSF-VEKQLMEEKKRKKLEEATA 488
+L + + +++ K +Q ++ L+K L ++E RS + Q M +K + +EE T
Sbjct: 1153 TELEDTLDSTATQQELRAKREQEVTVLKKAL--DEETRSHEAQVQEMRQKHAQAVEELTE 1210
Query: 489 A-RAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELR-KYKE 546
A A+ + +TL +L E + L + E + ++LE +VQEL+ K +
Sbjct: 1211 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1270
Query: 547 NEKDTEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQE 606
E+ L + +Q++ + + L+ + L + QL+ Q + ++ ++
Sbjct: 1271 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQ 1330
Query: 607 IKDLKQKIAEV 617
++ K+ ++
Sbjct: 1331 KLNVSTKLRQL 1341
Score = 51.6 bits (122), Expect = 2e-06
Identities = 54/258 (20%), Positives = 114/258 (44%), Gaps = 28/258 (10%)
Query: 383 LVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLH-- 440
+ R E++++ + +LQ +++ +Q+ +++ L QL +E LLQ +L
Sbjct: 847 VTRQEEEMQAKEDELQKTKERQQKAENELKELEQKH-------SQLTEEKNLLQEQLQAE 899
Query: 441 -----NAVQMKQK---DKQNISQLEKKLKAEQEARSFVEKQLMEEKKR---------KKL 483
A +M+ + KQ + ++ +++A E +QL E+K+ ++L
Sbjct: 900 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL 959
Query: 484 EEATAARAVAFAAASRGEC-TETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKV-QEL 541
EE AAR E + L + I ++ + KL+ + K+ E++I +L + +E
Sbjct: 960 EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE 1019
Query: 542 RKYKENEKDTEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQIL 601
K K K S +S ++ + + E S ++K L D Q+ Q QI
Sbjct: 1020 EKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIA 1079
Query: 602 QKDQEIKDLKQKIAEVMA 619
+ ++ ++++ +A
Sbjct: 1080 ELKMQLAKKEEELQAALA 1097
Score = 46.6 bits (109), Expect = 7e-05
Identities = 64/294 (21%), Positives = 121/294 (41%), Gaps = 48/294 (16%)
Query: 338 ATNGSIPSSSSKNEKKQK-------------CTSKSPSTHKDLMENCIPNNQLSKPDALV 384
A+ I +++ +NEKK K ++ DL + + S
Sbjct: 1666 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 1725
Query: 385 RLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQ 444
L+ + ++L+A + Q+E+EL + ++ + +R + Q+ E L N+L
Sbjct: 1726 ALQDEKRRLEARIA---QLEEELEEEQGNMEAMSDRVR----KATQQAEQLSNELATERS 1778
Query: 445 MKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTE 504
QK++ QLE++ K E RS + + ME + K + AA A + E
Sbjct: 1779 TAQKNESARQQLERQNK---ELRSKLHE--MEGAVKSKFKSTIAALEAKIA-----QLEE 1828
Query: 505 TLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRK----YKENEKDTEVLMSALSA 560
+ RE +A K L K K+ +++E+ L+V++ RK YKE + + L
Sbjct: 1829 QVEQEAREKQAATKSL----KQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKR 1884
Query: 561 MQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKI 614
++ + ++A R +R+L+ A +E+ LK K+
Sbjct: 1885 QLEEAEEESQRINANRR----------KLQRELDEATESNEAMGREVNALKSKL 1928
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 65.5 bits (158), Expect = 2e-10
Identities = 96/460 (20%), Positives = 189/460 (41%), Gaps = 70/460 (15%)
Query: 183 QKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKK 242
Q+E +++ +L Q L E+ LQ Q E EA + L S++ I + + KK
Sbjct: 1332 QEETRQKLNVSTKLRQ--LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSD---SKKK 1386
Query: 243 LSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNNDL 302
L +E E+GK++ + +EIE + K D
Sbjct: 1387 LQDFASTVEALEEGKKRFQ----------------------KEIENLTQQYEEKAAAYDK 1424
Query: 303 VGSTENLLKE--DSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKS 360
+ T+N L++ D N + + R + SSK ++ +++
Sbjct: 1425 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERD-RAEA 1483
Query: 361 PSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERG 420
+ K+ + +A LE+ K LKA+++ + ++ + L ++R
Sbjct: 1484 EAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRA 1543
Query: 421 IRSEMGQLRQENELLQNKLHNAVQMKQKDKQNI----SQLEKKLKAEQEARSFVEKQLME 476
+ ++M +++ + E L+++L K + + N+ Q E+ L+A E +QL
Sbjct: 1544 LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQR 1603
Query: 477 E--KKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIREL 534
+ + +LE+ RA+A AA + L +++LE + + Q+R+L
Sbjct: 1604 QLHEYETELEDERKQRALAAAAKKK------LEGDLKDLELQADSAIKGREEAIKQLRKL 1657
Query: 535 ELKVQELRK---------------YKENEKDTEVLMSALSAMQD---------KTQHLE- 569
+ ++++ ++ KENEK + L + L +Q+ K LE
Sbjct: 1658 QAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEK 1717
Query: 570 NSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKD 609
L+ E L +AL D KR+LE +I Q ++E+++
Sbjct: 1718 EELAEELASSLSGRNALQDEKRRLE---ARIAQLEEELEE 1754
Score = 57.8 bits (138), Expect = 3e-08
Identities = 102/491 (20%), Positives = 212/491 (43%), Gaps = 63/491 (12%)
Query: 180 LRKQKEVQKENEFYMQLLQQA---LPPEQQMLQKQEK-------EAEE-----AAKG--- 221
L+K KE Q++ E ++ L+Q L E+ +LQ+Q + EAEE AAK
Sbjct: 868 LQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQEL 927
Query: 222 ---LPDMDSSILIHHNGGIPAN---KKLSTTLPEIEYREKGKEKDKDAKKHNLG-INNNN 274
L +M++ + + G KK++ + ++E E+ +E++ +K L +
Sbjct: 928 EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLE--EQLEEEEAARQKLQLEKVTAEA 985
Query: 275 ILQPVDSKIQEIEYMENHINSKR--LNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSS 332
++ ++ +I ++ N ++ +R L + T NL +E+ + KN + + N
Sbjct: 986 KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE------EKAKNLTKLKNKH 1039
Query: 333 PRSHSATNGSIPSSSSKNEKKQKCTSKSPSTHKDLMENCIP--------NNQLSKPD--- 381
S + ++ +K K D E QL+K +
Sbjct: 1040 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1099
Query: 382 --ALVRLEQDIKKLKADLQASRQVE---QELRSQISSLSSTERGIRSEMGQLRQENELLQ 436
AL RL+ +I + L+ R++E +L+ + S + + L +E E L+
Sbjct: 1100 QAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALK 1159
Query: 437 NKLHNAV-------QMKQKDKQNISQLEKKLKAEQEARSF-VEKQLMEEKKRKKLEEATA 488
+L + + +++ K +Q ++ L+K L ++E RS + Q M +K + +EE T
Sbjct: 1160 TELEDTLDSTATQQELRAKREQEVTVLKKAL--DEETRSHEAQVQEMRQKHAQAVEELTE 1217
Query: 489 A-RAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELR-KYKE 546
A A+ + +TL +L E + L + E + ++LE +VQEL+ K +
Sbjct: 1218 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1277
Query: 547 NEKDTEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQE 606
E+ L + +Q++ + + L+ + L + QL+ Q + ++ ++
Sbjct: 1278 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQ 1337
Query: 607 IKDLKQKIAEV 617
++ K+ ++
Sbjct: 1338 KLNVSTKLRQL 1348
Score = 51.6 bits (122), Expect = 2e-06
Identities = 54/258 (20%), Positives = 114/258 (44%), Gaps = 28/258 (10%)
Query: 383 LVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLH-- 440
+ R E++++ + +LQ +++ +Q+ +++ L QL +E LLQ +L
Sbjct: 854 VTRQEEEMQAKEDELQKTKERQQKAENELKELEQKH-------SQLTEEKNLLQEQLQAE 906
Query: 441 -----NAVQMKQK---DKQNISQLEKKLKAEQEARSFVEKQLMEEKKR---------KKL 483
A +M+ + KQ + ++ +++A E +QL E+K+ ++L
Sbjct: 907 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL 966
Query: 484 EEATAARAVAFAAASRGEC-TETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKV-QEL 541
EE AAR E + L + I ++ + KL+ + K+ E++I +L + +E
Sbjct: 967 EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE 1026
Query: 542 RKYKENEKDTEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQIL 601
K K K S +S ++ + + E S ++K L D Q+ Q QI
Sbjct: 1027 EKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIA 1086
Query: 602 QKDQEIKDLKQKIAEVMA 619
+ ++ ++++ +A
Sbjct: 1087 ELKMQLAKKEEELQAALA 1104
Score = 46.6 bits (109), Expect = 7e-05
Identities = 64/294 (21%), Positives = 121/294 (41%), Gaps = 48/294 (16%)
Query: 338 ATNGSIPSSSSKNEKKQK-------------CTSKSPSTHKDLMENCIPNNQLSKPDALV 384
A+ I +++ +NEKK K ++ DL + + S
Sbjct: 1673 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 1732
Query: 385 RLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQ 444
L+ + ++L+A + Q+E+EL + ++ + +R + Q+ E L N+L
Sbjct: 1733 ALQDEKRRLEARIA---QLEEELEEEQGNMEAMSDRVR----KATQQAEQLSNELATERS 1785
Query: 445 MKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTE 504
QK++ QLE++ K E RS + + ME + K + AA A + E
Sbjct: 1786 TAQKNESARQQLERQNK---ELRSKLHE--MEGAVKSKFKSTIAALEAKIA-----QLEE 1835
Query: 505 TLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRK----YKENEKDTEVLMSALSA 560
+ RE +A K L K K+ +++E+ L+V++ RK YKE + + L
Sbjct: 1836 QVEQEAREKQAATKSL----KQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKR 1891
Query: 561 MQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKI 614
++ + ++A R +R+L+ A +E+ LK K+
Sbjct: 1892 QLEEAEEESQRINANRR----------KLQRELDEATESNEAMGREVNALKSKL 1935
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 65.5 bits (158), Expect = 2e-10
Identities = 96/460 (20%), Positives = 189/460 (41%), Gaps = 70/460 (15%)
Query: 183 QKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKK 242
Q+E +++ +L Q L E+ LQ Q E EA + L S++ I + + KK
Sbjct: 1332 QEETRQKLNVSTKLRQ--LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSD---SKKK 1386
Query: 243 LSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNNDL 302
L +E E+GK++ + +EIE + K D
Sbjct: 1387 LQDFASTVEALEEGKKRFQ----------------------KEIENLTQQYEEKAAAYDK 1424
Query: 303 VGSTENLLKE--DSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKS 360
+ T+N L++ D N + + R + SSK ++ +++
Sbjct: 1425 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERD-RAEA 1483
Query: 361 PSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERG 420
+ K+ + +A LE+ K LKA+++ + ++ + L ++R
Sbjct: 1484 EAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRA 1543
Query: 421 IRSEMGQLRQENELLQNKLHNAVQMKQKDKQNI----SQLEKKLKAEQEARSFVEKQLME 476
+ ++M +++ + E L+++L K + + N+ Q E+ L+A E +QL
Sbjct: 1544 LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQR 1603
Query: 477 E--KKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIREL 534
+ + +LE+ RA+A AA + L +++LE + + Q+R+L
Sbjct: 1604 QLHEYETELEDERKQRALAAAAKKK------LEGDLKDLELQADSAIKGREEAIKQLRKL 1657
Query: 535 ELKVQELRK---------------YKENEKDTEVLMSALSAMQD---------KTQHLE- 569
+ ++++ ++ KENEK + L + L +Q+ K LE
Sbjct: 1658 QAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEK 1717
Query: 570 NSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKD 609
L+ E L +AL D KR+LE +I Q ++E+++
Sbjct: 1718 EELAEELASSLSGRNALQDEKRRLE---ARIAQLEEELEE 1754
Score = 57.8 bits (138), Expect = 3e-08
Identities = 102/491 (20%), Positives = 212/491 (43%), Gaps = 63/491 (12%)
Query: 180 LRKQKEVQKENEFYMQLLQQA---LPPEQQMLQKQEK-------EAEE-----AAKG--- 221
L+K KE Q++ E ++ L+Q L E+ +LQ+Q + EAEE AAK
Sbjct: 868 LQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQEL 927
Query: 222 ---LPDMDSSILIHHNGGIPAN---KKLSTTLPEIEYREKGKEKDKDAKKHNLG-INNNN 274
L +M++ + + G KK++ + ++E E+ +E++ +K L +
Sbjct: 928 EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLE--EQLEEEEAARQKLQLEKVTAEA 985
Query: 275 ILQPVDSKIQEIEYMENHINSKR--LNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSS 332
++ ++ +I ++ N ++ +R L + T NL +E+ + KN + + N
Sbjct: 986 KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE------EKAKNLTKLKNKH 1039
Query: 333 PRSHSATNGSIPSSSSKNEKKQKCTSKSPSTHKDLMENCIP--------NNQLSKPD--- 381
S + ++ +K K D E QL+K +
Sbjct: 1040 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1099
Query: 382 --ALVRLEQDIKKLKADLQASRQVE---QELRSQISSLSSTERGIRSEMGQLRQENELLQ 436
AL RL+ +I + L+ R++E +L+ + S + + L +E E L+
Sbjct: 1100 QAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALK 1159
Query: 437 NKLHNAV-------QMKQKDKQNISQLEKKLKAEQEARSF-VEKQLMEEKKRKKLEEATA 488
+L + + +++ K +Q ++ L+K L ++E RS + Q M +K + +EE T
Sbjct: 1160 TELEDTLDSTATQQELRAKREQEVTVLKKAL--DEETRSHEAQVQEMRQKHAQAVEELTE 1217
Query: 489 A-RAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELR-KYKE 546
A A+ + +TL +L E + L + E + ++LE +VQEL+ K +
Sbjct: 1218 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1277
Query: 547 NEKDTEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQE 606
E+ L + +Q++ + + L+ + L + QL+ Q + ++ ++
Sbjct: 1278 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQ 1337
Query: 607 IKDLKQKIAEV 617
++ K+ ++
Sbjct: 1338 KLNVSTKLRQL 1348
Score = 51.6 bits (122), Expect = 2e-06
Identities = 54/258 (20%), Positives = 114/258 (44%), Gaps = 28/258 (10%)
Query: 383 LVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLH-- 440
+ R E++++ + +LQ +++ +Q+ +++ L QL +E LLQ +L
Sbjct: 854 VTRQEEEMQAKEDELQKTKERQQKAENELKELEQKH-------SQLTEEKNLLQEQLQAE 906
Query: 441 -----NAVQMKQK---DKQNISQLEKKLKAEQEARSFVEKQLMEEKKR---------KKL 483
A +M+ + KQ + ++ +++A E +QL E+K+ ++L
Sbjct: 907 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL 966
Query: 484 EEATAARAVAFAAASRGEC-TETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKV-QEL 541
EE AAR E + L + I ++ + KL+ + K+ E++I +L + +E
Sbjct: 967 EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE 1026
Query: 542 RKYKENEKDTEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQIL 601
K K K S +S ++ + + E S ++K L D Q+ Q QI
Sbjct: 1027 EKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIA 1086
Query: 602 QKDQEIKDLKQKIAEVMA 619
+ ++ ++++ +A
Sbjct: 1087 ELKMQLAKKEEELQAALA 1104
Score = 46.6 bits (109), Expect = 7e-05
Identities = 64/294 (21%), Positives = 121/294 (41%), Gaps = 48/294 (16%)
Query: 338 ATNGSIPSSSSKNEKKQK-------------CTSKSPSTHKDLMENCIPNNQLSKPDALV 384
A+ I +++ +NEKK K ++ DL + + S
Sbjct: 1673 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 1732
Query: 385 RLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQ 444
L+ + ++L+A + Q+E+EL + ++ + +R + Q+ E L N+L
Sbjct: 1733 ALQDEKRRLEARIA---QLEEELEEEQGNMEAMSDRVR----KATQQAEQLSNELATERS 1785
Query: 445 MKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTE 504
QK++ QLE++ K E RS + + ME + K + AA A + E
Sbjct: 1786 TAQKNESARQQLERQNK---ELRSKLHE--MEGAVKSKFKSTIAALEAKIA-----QLEE 1835
Query: 505 TLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRK----YKENEKDTEVLMSALSA 560
+ RE +A K L K K+ +++E+ L+V++ RK YKE + + L
Sbjct: 1836 QVEQEAREKQAATKSL----KQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKR 1891
Query: 561 MQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKI 614
++ + ++A R +R+L+ A +E+ LK K+
Sbjct: 1892 QLEEAEEESQRINANRR----------KLQRELDEATESNEAMGREVNALKSKL 1935
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 65.5 bits (158), Expect = 2e-10
Identities = 96/460 (20%), Positives = 189/460 (41%), Gaps = 70/460 (15%)
Query: 183 QKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKK 242
Q+E +++ +L Q L E+ LQ Q E EA + L S++ I + + KK
Sbjct: 1325 QEETRQKLNVSTKLRQ--LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSD---SKKK 1379
Query: 243 LSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNNDL 302
L +E E+GK++ + +EIE + K D
Sbjct: 1380 LQDFASTVEALEEGKKRFQ----------------------KEIENLTQQYEEKAAAYDK 1417
Query: 303 VGSTENLLKE--DSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKS 360
+ T+N L++ D N + + R + SSK ++ +++
Sbjct: 1418 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERD-RAEA 1476
Query: 361 PSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERG 420
+ K+ + +A LE+ K LKA+++ + ++ + L ++R
Sbjct: 1477 EAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRA 1536
Query: 421 IRSEMGQLRQENELLQNKLHNAVQMKQKDKQNI----SQLEKKLKAEQEARSFVEKQLME 476
+ ++M +++ + E L+++L K + + N+ Q E+ L+A E +QL
Sbjct: 1537 LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQR 1596
Query: 477 E--KKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIREL 534
+ + +LE+ RA+A AA + L +++LE + + Q+R+L
Sbjct: 1597 QLHEYETELEDERKQRALAAAAKKK------LEGDLKDLELQADSAIKGREEAIKQLRKL 1650
Query: 535 ELKVQELRK---------------YKENEKDTEVLMSALSAMQD---------KTQHLE- 569
+ ++++ ++ KENEK + L + L +Q+ K LE
Sbjct: 1651 QAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEK 1710
Query: 570 NSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKD 609
L+ E L +AL D KR+LE +I Q ++E+++
Sbjct: 1711 EELAEELASSLSGRNALQDEKRRLE---ARIAQLEEELEE 1747
Score = 57.8 bits (138), Expect = 3e-08
Identities = 102/491 (20%), Positives = 212/491 (43%), Gaps = 63/491 (12%)
Query: 180 LRKQKEVQKENEFYMQLLQQA---LPPEQQMLQKQEK-------EAEE-----AAKG--- 221
L+K KE Q++ E ++ L+Q L E+ +LQ+Q + EAEE AAK
Sbjct: 861 LQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQEL 920
Query: 222 ---LPDMDSSILIHHNGGIPAN---KKLSTTLPEIEYREKGKEKDKDAKKHNLG-INNNN 274
L +M++ + + G KK++ + ++E E+ +E++ +K L +
Sbjct: 921 EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLE--EQLEEEEAARQKLQLEKVTAEA 978
Query: 275 ILQPVDSKIQEIEYMENHINSKR--LNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSS 332
++ ++ +I ++ N ++ +R L + T NL +E+ + KN + + N
Sbjct: 979 KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE------EKAKNLTKLKNKH 1032
Query: 333 PRSHSATNGSIPSSSSKNEKKQKCTSKSPSTHKDLMENCIP--------NNQLSKPD--- 381
S + ++ +K K D E QL+K +
Sbjct: 1033 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1092
Query: 382 --ALVRLEQDIKKLKADLQASRQVE---QELRSQISSLSSTERGIRSEMGQLRQENELLQ 436
AL RL+ +I + L+ R++E +L+ + S + + L +E E L+
Sbjct: 1093 QAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALK 1152
Query: 437 NKLHNAV-------QMKQKDKQNISQLEKKLKAEQEARSF-VEKQLMEEKKRKKLEEATA 488
+L + + +++ K +Q ++ L+K L ++E RS + Q M +K + +EE T
Sbjct: 1153 TELEDTLDSTATQQELRAKREQEVTVLKKAL--DEETRSHEAQVQEMRQKHAQAVEELTE 1210
Query: 489 A-RAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELR-KYKE 546
A A+ + +TL +L E + L + E + ++LE +VQEL+ K +
Sbjct: 1211 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1270
Query: 547 NEKDTEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQE 606
E+ L + +Q++ + + L+ + L + QL+ Q + ++ ++
Sbjct: 1271 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQ 1330
Query: 607 IKDLKQKIAEV 617
++ K+ ++
Sbjct: 1331 KLNVSTKLRQL 1341
Score = 51.6 bits (122), Expect = 2e-06
Identities = 54/258 (20%), Positives = 114/258 (44%), Gaps = 28/258 (10%)
Query: 383 LVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLH-- 440
+ R E++++ + +LQ +++ +Q+ +++ L QL +E LLQ +L
Sbjct: 847 VTRQEEEMQAKEDELQKTKERQQKAENELKELEQKH-------SQLTEEKNLLQEQLQAE 899
Query: 441 -----NAVQMKQK---DKQNISQLEKKLKAEQEARSFVEKQLMEEKKR---------KKL 483
A +M+ + KQ + ++ +++A E +QL E+K+ ++L
Sbjct: 900 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL 959
Query: 484 EEATAARAVAFAAASRGEC-TETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKV-QEL 541
EE AAR E + L + I ++ + KL+ + K+ E++I +L + +E
Sbjct: 960 EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE 1019
Query: 542 RKYKENEKDTEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQIL 601
K K K S +S ++ + + E S ++K L D Q+ Q QI
Sbjct: 1020 EKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIA 1079
Query: 602 QKDQEIKDLKQKIAEVMA 619
+ ++ ++++ +A
Sbjct: 1080 ELKMQLAKKEEELQAALA 1097
Score = 46.6 bits (109), Expect = 7e-05
Identities = 64/294 (21%), Positives = 121/294 (41%), Gaps = 48/294 (16%)
Query: 338 ATNGSIPSSSSKNEKKQK-------------CTSKSPSTHKDLMENCIPNNQLSKPDALV 384
A+ I +++ +NEKK K ++ DL + + S
Sbjct: 1666 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 1725
Query: 385 RLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQ 444
L+ + ++L+A + Q+E+EL + ++ + +R + Q+ E L N+L
Sbjct: 1726 ALQDEKRRLEARIA---QLEEELEEEQGNMEAMSDRVR----KATQQAEQLSNELATERS 1778
Query: 445 MKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTE 504
QK++ QLE++ K E RS + + ME + K + AA A + E
Sbjct: 1779 TAQKNESARQQLERQNK---ELRSKLHE--MEGAVKSKFKSTIAALEAKIA-----QLEE 1828
Query: 505 TLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRK----YKENEKDTEVLMSALSA 560
+ RE +A K L K K+ +++E+ L+V++ RK YKE + + L
Sbjct: 1829 QVEQEAREKQAATKSL----KQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKR 1884
Query: 561 MQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKI 614
++ + ++A R +R+L+ A +E+ LK K+
Sbjct: 1885 QLEEAEEESQRINANRR----------KLQRELDEATESNEAMGREVNALKSKL 1928
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 63.5 bits (153), Expect = 6e-10
Identities = 92/448 (20%), Positives = 183/448 (40%), Gaps = 33/448 (7%)
Query: 184 KEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKKL 243
K + K E Y Q L+ L + ++L+++E + ++ + + DS L + L
Sbjct: 560 KNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYI---DSQKLEN------IKMDL 610
Query: 244 STTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNNDLV 303
S +L IE ++ K+ DA+ L + ++ + + E K++ ND+
Sbjct: 611 SYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQ 670
Query: 304 GSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKN-EKKQKCTSKSPS 362
L + + K N + S +G +P N E + K T
Sbjct: 671 LYQSQLEAKKKMQVDLE--KELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKE 728
Query: 363 THKDLMENCIPNNQL-------SKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLS 415
+K++ EN ++ S P + RL ++I+ +L + +L S++
Sbjct: 729 LNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKE 788
Query: 416 STERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLM 475
S +G+ E+G+ + + Q+ + Q Q K E+K K E + ++++
Sbjct: 789 SRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIV 848
Query: 476 E-EKKRKKLEEATAA--RAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIR 532
K+ +K + + A +++ E T ++ R+ E+E ++L + R
Sbjct: 849 NLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVER 908
Query: 533 ELELKVQELRKYKENEKDTEVLMSALSAMQDKTQHLENSLSAE-TRIKLDLFSALG---D 588
E L ++L++ E K L+ +D + L+ SL E ++K D+ + D
Sbjct: 909 EKTLITEKLQQTLEEVK-------TLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNID 961
Query: 589 AKRQLEIAQGQILQKDQEIKDLKQKIAE 616
+ QL A + Q + I LK KI+E
Sbjct: 962 TQEQLRNALESLKQHQETINTLKSKISE 989
Score = 63.2 bits (152), Expect = 8e-10
Identities = 90/424 (21%), Positives = 171/424 (40%), Gaps = 57/424 (13%)
Query: 208 LQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKKLSTTLPEIEYREKGKEKDKDAKKHN 267
L++ ++ +E + + + + I I+ ++ KL +P + ++ K+ +
Sbjct: 1244 LKEHQETIDELRRSVSEKTAQI-INTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQ 1302
Query: 268 LGINNNNILQPVDSKIQEIEYMENHINSKRLNNDLVGSTENLLKEDSCTASSKNYKNASG 327
+N +L + + RLN S E + + K K A
Sbjct: 1303 ETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALE 1362
Query: 328 VVNSSPRSH-SATNGSIPSSSSKNEKKQKCTSKSPSTHKDL--MENCIPNNQLSKPDALV 384
V + + H T I S SK E+ K T K + ME P K AL+
Sbjct: 1363 VKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKP-----KDSALL 1417
Query: 385 RLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQE-NELLQNKLHNAV 443
R+E ++ L LQ S + + + L + ++SE QL++ E++ L
Sbjct: 1418 RIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEE 1477
Query: 444 QMK------QKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAA 497
++K ++ ++ I++L L ++ S ++KQL EA
Sbjct: 1478 ELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQL----------EAI---------- 1517
Query: 498 SRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKENEKDTEVLMSA 557
+ L+N+I+E+ + ++ + QI E++ KV EL+++KE+ K + SA
Sbjct: 1518 -----NDKLQNKIQEIYEKEEQFNIK------QISEVQEKVNELKQFKEHRKAKD---SA 1563
Query: 558 LSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAEV 617
L +++ K L N L + + KR E Q +++DQ LK+ E+
Sbjct: 1564 LQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQ---IERDQ----LKENTKEI 1616
Query: 618 MAVM 621
+A M
Sbjct: 1617 VAKM 1620
Score = 61.2 bits (147), Expect = 3e-09
Identities = 95/469 (20%), Positives = 195/469 (41%), Gaps = 62/469 (13%)
Query: 182 KQKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANK 241
+ K V KE + +Q LQ+ L E L++ KE AK L + + H K
Sbjct: 1436 EMKSVAKEKDD-LQRLQEVLQSESDQLKENIKEI--VAKHLETEEELKVAHC-----CLK 1487
Query: 242 KLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNND 301
+ T+ E+ KE + + L N+ + +KIQEI E N K+++
Sbjct: 1488 EQEETINELRVNLSEKETEISTIQKQLEAINDKL----QNKIQEIYEKEEQFNIKQISE- 1542
Query: 302 LVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSP 361
V N LK+ +K +S+ +S + + + +++++ + K
Sbjct: 1543 -VQEKVNELKQ---------FKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEK 1592
Query: 362 STHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVE------------QELRS 409
K + E Q+ + +L+++ K++ A ++ S++ E QE
Sbjct: 1593 EEMKRVQEAL----QIERD----QLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMC 1644
Query: 410 QISSLSSTERGIRSEMGQLRQENELLQNKLH-NAVQMKQ--KDKQNISQLEKKLKAEQEA 466
+I L + + + EN L LH N +M+ K++ ++ +E+ LK E++
Sbjct: 1645 EIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQ 1704
Query: 467 RSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKV 526
K+ + E + LE+ + V E + LR + E E + D++
Sbjct: 1705 L----KENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEH 1760
Query: 527 KEDQIRELELKVQ-ELR----KYKENEKDTEVLMSALSAMQDKTQHLENSLSAETRIKLD 581
D ++ +LK+Q ELR KE ++ + L +S DK +++ L
Sbjct: 1761 SNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSN----- 1815
Query: 582 LFSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAEVMAVMPSITYSAAT 630
+ L + ++L+ + Q++ +++ + ++K++E+ + I + T
Sbjct: 1816 --AKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLT 1862
Score = 58.5 bits (140), Expect = 2e-08
Identities = 96/461 (20%), Positives = 185/461 (40%), Gaps = 52/461 (11%)
Query: 183 QKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANK- 241
QKE+ KE E L ++ + + L+ E E K + D + I I + K
Sbjct: 726 QKELNKEVEENEALREEVILLSE--LKSLPSEVERLRKEIQDKSEELHI-----ITSEKD 778
Query: 242 KLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSK----- 296
KL + + E R +G ++ K +L +N + D + Q + + K
Sbjct: 779 KLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNY-KSTDQEFQNFKTLHMDFEQKYKMVL 837
Query: 297 ----RLNNDLVGSTENLLKEDSCTASSK---NYKNASGVVNSSPRSHSATNGSIPSSSSK 349
R+N ++V ++ K DS + K +YK + R + +
Sbjct: 838 EENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQE--LQEKTREVQERLNEMEQLKEQ 895
Query: 350 NEKKQKCTSKSPSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASR-QVEQELR 408
E + T ++ K L+ + L + L + + D+K+L+ LQ R Q++ ++
Sbjct: 896 LENRDS-TLQTVEREKTLITEKLQQT-LEEVKTLTQEKDDLKQLQESLQIERDQLKSDIH 953
Query: 409 SQISSLSSTERGIRSEMGQLRQENEL---LQNKLHNAVQMKQKDKQNISQLEKKLKAEQE 465
++ T+ +R+ + L+Q E L++K+ V ++N E K + +Q+
Sbjct: 954 DTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTG--ETKDEFQQK 1011
Query: 466 ARSFVEKQLMEEKKRKKL-------EEATAARAVAFAAASRGECTETLRNRIRELEAEGK 518
+KQ +E K + L E R + + E + L + I E E
Sbjct: 1012 MVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKT 1071
Query: 519 KLTMDMKVKEDQIRELELKVQELRKYKENEKDTEVLMSALSAMQDKTQHL--ENSLSAET 576
L ++++ + EL L EL+K +E Q+K + E LS
Sbjct: 1072 DLKENIEMTIENQEELRLLGDELKKQQE------------IVAQEKNHAIKKEGELSRTC 1119
Query: 577 RIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAEV 617
++ L + +QL+ Q Q+L +E+ ++++KI E+
Sbjct: 1120 DRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEI 1160
Score = 58.2 bits (139), Expect = 2e-08
Identities = 89/474 (18%), Positives = 204/474 (43%), Gaps = 60/474 (12%)
Query: 199 QALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKKLSTTLPEIEYREKGKE 258
Q L + + +Q++ E E+ + L + DS++ +KL TL E++ + K+
Sbjct: 873 QELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKD 932
Query: 259 KDKDAKKHNLGINNN----NILQPVDSKIQEIEYMENHINSKRLNNDLVGSTENLLKEDS 314
K ++ +L I + +I V+ I E + N + S + + + + + ++ + E+
Sbjct: 933 DLKQLQE-SLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEV 991
Query: 315 C--------TASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKN----EKKQKCTS--KS 360
T +K+ V + A N ++ K+ E+++K S +
Sbjct: 992 SRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQE 1051
Query: 361 PSTHKDLMENCIPNNQLSKPDALVRLE------QDIKKLKADLQASRQV----------- 403
+ + ++E+ I + K D +E ++++ L +L+ +++
Sbjct: 1052 KNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKK 1111
Query: 404 EQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAE 463
E EL L+ E ++ + QL+++ + L N +M++K + I L+ +LK +
Sbjct: 1112 EGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINE-IENLKNELKNK 1170
Query: 464 QEARSFVEKQLME--EKKRKKLEEATAARAVAFAAASRGECTET----LRNRIRELEAEG 517
+ +E + +E +K + EE + + ET LR IRE+EA G
Sbjct: 1171 ELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATG 1230
Query: 518 KKLTMDMKVKEDQIRELELKVQELRK-----------YKENEKDTEVLMSALSAMQDKTQ 566
+ ++K+ ++E + + ELR+ ++ EK L + + ++ +
Sbjct: 1231 LQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQE 1290
Query: 567 HLEN----SLSAETRIKLDLFSALGDAKRQLEIAQGQI--LQKDQEIKDLKQKI 614
L N S + ET +L+L + K +A+ ++ L+ +++ ++ +++I
Sbjct: 1291 LLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEI 1344
Score = 53.9 bits (128), Expect = 5e-07
Identities = 78/365 (21%), Positives = 151/365 (41%), Gaps = 74/365 (20%)
Query: 250 IEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNNDLVGSTENL 309
+E R + EKD+ A+ + ++LQ V + E +EN L LV S+
Sbjct: 364 LETRAQAMEKDQLAQL----LEEKDLLQKVQN-----EKIEN------LTRMLVTSSSLT 408
Query: 310 LKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPSTHKDLME 369
L+++ + G +N S+ A +IP++ + K E
Sbjct: 409 LQQELKAKRKRRVTWCLGKINKMKNSNYADQFNIPTNITTKTHKLSINLLREIDESVCSE 468
Query: 370 NCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQE-LRSQISSLSSTERGIRSEMGQL 428
+ + +N L D L +E + A++ + QE + S+++SL + + + QL
Sbjct: 469 SDVFSNTL---DTLSEIEWN--------PATKLLNQENIESELNSLRADYDNLVLDYEQL 517
Query: 429 RQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATA 488
R E E ++ KL ++ D LE+K K +QE QL+ E
Sbjct: 518 RTEKEEMELKLK-----EKNDLDEFEALERKTKKDQEM------QLIHE----------- 555
Query: 489 ARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKENE 548
L+N ++ E + L ++ K + +RE E ++++L++Y +++
Sbjct: 556 --------------ISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQ 601
Query: 549 KDTEVLMS---ALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQ 605
K + M +L +++D Q + AET DAKR+ + + L+ +
Sbjct: 602 KLENIKMDLSYSLESIEDPKQMKQTLFDAET--------VALDAKRESAFLRSENLELKE 653
Query: 606 EIKDL 610
++K+L
Sbjct: 654 KMKEL 658
Score = 47.8 bits (112), Expect = 3e-05
Identities = 91/461 (19%), Positives = 183/461 (39%), Gaps = 58/461 (12%)
Query: 180 LRKQKEVQ------KENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHH 233
L KQ+E++ KE++ + L+ + + + +K+ E + L D I
Sbjct: 1717 LEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEEL 1776
Query: 234 NGGIPANKKLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENH- 292
K+ T+ ++ +G +K K N+ + N + KIQE++ E+
Sbjct: 1777 RIAHMHLKEQQETIDKL----RGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQL 1832
Query: 293 INSKRLNNDL---VGSTENL---LKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSS 346
I K+ N+ V E L +K+ S T S +N +N + + H
Sbjct: 1833 ITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIEN----LNLAQKLH---------- 1878
Query: 347 SSKNEKKQKCTSKSPSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQE 406
+N ++ K K + L + + ++LE+D +LK LQ ++ + E
Sbjct: 1879 --ENLEEMKSVMKE-------------RDNLRRVEETLKLERD--QLKESLQETKARDLE 1921
Query: 407 LRSQISSLSSTERGIRSEMGQLRQENEL-------LQNKLHNAVQMKQKDKQNISQLEKK 459
++ ++ + + + + +LR++ +Q L + QK Q + + E +
Sbjct: 1922 IQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQ 1981
Query: 460 LKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKK 519
L +E + K++ E ++ KK EA ++ + T+ L + E+ K+
Sbjct: 1982 LLRVKEDVNMSHKKINEMEQLKKQFEAQNL-SMQSVRMDNFQLTKKLHESLEEIRIVAKE 2040
Query: 520 LTMDMKVKEDQIRELELKVQELRKYKENEKDTEVLMSALSAMQDKTQHLENSLSAE-TRI 578
++KE E + + LR+ ++ + + D QHL SL + +RI
Sbjct: 2041 RDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLTESLREKCSRI 2100
Query: 579 KLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAEVMA 619
K +L + E L ++EI+ K+ V A
Sbjct: 2101 K-ELLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSMRVKA 2140
Score = 37.7 bits (86), Expect = 0.034
Identities = 72/419 (17%), Positives = 167/419 (39%), Gaps = 54/419 (12%)
Query: 242 KLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNND 301
K L E E E+ +KD++ + + N N+++ + Q++E N ++SK +
Sbjct: 529 KEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLE---NELSSKV---E 582
Query: 302 LVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSP 361
L+ E+ +K+ S+ +N ++ S S K K+ +++
Sbjct: 583 LLREKEDQIKKLQEYIDSQKLENIKMDLSYSLES---------IEDPKQMKQTLFDAETV 633
Query: 362 STHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASR-QVEQELRSQISSLSSTERG 420
+ + + L + + L K+++ D+Q + Q+E + + Q+ E+
Sbjct: 634 ALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVD----LEKE 689
Query: 421 IRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVE--------- 471
++S ++ + L+ K+ + + + I+ L+K+L E E +
Sbjct: 690 LQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSEL 749
Query: 472 KQLMEEKKRKKLEEATAARAVAFAAASRGECTETL---RNRIRELEAEGKKLTMDMKVKE 528
K L E +R + E + + + + + + +R++ L E K D+ +
Sbjct: 750 KSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQ 809
Query: 529 DQIRELELKVQELR--------KYK----ENE----------KDTEVLMSALSAMQDKTQ 566
+ + + Q + KYK ENE K+ + S+L A++ +
Sbjct: 810 SNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELS 869
Query: 567 HLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAEVMAVMPSIT 625
+ L +TR + + + K QLE + ++E + +K+ + + + ++T
Sbjct: 870 YKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLT 928
Score = 34.7 bits (78), Expect = 0.29
Identities = 38/200 (19%), Positives = 84/200 (42%), Gaps = 39/200 (19%)
Query: 387 EQDIKKLKADLQASRQVEQELRSQISS--------LSSTERGIRSEMGQLRQEN-ELLQN 437
EQD+K LK + + Q L++ ++S + + S QL E L+N
Sbjct: 2329 EQDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELEN 2388
Query: 438 KLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAA 497
LH A + + I +++K+L+ + + ++ ++ E K
Sbjct: 2389 SLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNK------------------ 2430
Query: 498 SRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELK-----VQELRKYKENEKDTE 552
C E + I+ L+ K+ + K +++I +L++K +++++ KE EK+
Sbjct: 2431 ----CLEKTKETIQVLQ---DKVALGAKPYKEEIEDLKMKLVKIDLEKMKNAKEFEKEIS 2483
Query: 553 VLMSALSAMQDKTQHLENSL 572
+ + ++ + L +L
Sbjct: 2484 ATKATVEYQKEVIRLLRENL 2503
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 63.5 bits (153), Expect = 6e-10
Identities = 98/490 (20%), Positives = 200/490 (40%), Gaps = 71/490 (14%)
Query: 181 RKQKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPAN 240
+++ ++ +E E + L++A ++ +K E K D++ + L H
Sbjct: 1137 KQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALR 1196
Query: 241 KKLSTTLPEI--------EYREKGKEKDKDAKKHNLGINNN------------NILQPVD 280
KK + ++ E+ ++K +++ + K +++N + + ++
Sbjct: 1197 KKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLE 1256
Query: 281 SKIQEIEYMENHINSKRLNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATN 340
++ E++ E +RL NDL L E + + K+A +V+ RS A+
Sbjct: 1257 DQVSELKTKEEE--QQRLINDLTAQRARLQTEAGEYSRQLDEKDA--LVSQLSRSKQAST 1312
Query: 341 GSIPSSSSKNEKKQKCTSK-----SPSTHK-DLMENCIPNNQLSKPD---ALVRLEQDIK 391
I + E++ K + S H DL+ Q K + AL + ++
Sbjct: 1313 QQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVA 1372
Query: 392 KLKAD-----LQASRQVEQELRSQISSLSSTER---GIRSEMGQLRQENELLQNKLHNAV 443
+ + +Q + ++E+ + L E + ++ L + + LQN++ + +
Sbjct: 1373 QWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLM 1432
Query: 444 QMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECT 503
++ + L+KK R+F +K L E K++ E T A A SR T
Sbjct: 1433 LDVERSNAACAALDKK------QRNF-DKVLSEWKQKY---EETQAELEASQKESRSLST 1482
Query: 504 ETLR---------NRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKEN-EKDTEV 553
E + +++ L E K L ++ +QI E ++ EL K K+ E++
Sbjct: 1483 ELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCE 1542
Query: 554 LMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQK 613
+ +AL + +H E + RI+L+L + R+ I +KD+EI LK+
Sbjct: 1543 IQAALEEAEASLEHEEGKI---LRIQLELNQVKSEVDRK-------IAEKDEEIDQLKRN 1592
Query: 614 IAEVMAVMPS 623
V+ M S
Sbjct: 1593 HTRVVETMQS 1602
Score = 54.7 bits (130), Expect = 3e-07
Identities = 51/239 (21%), Positives = 108/239 (45%), Gaps = 14/239 (5%)
Query: 383 LVRLEQDIKKLKADLQASRQVEQELRSQISSL----SSTERGIRSEMGQLRQENELLQNK 438
+ ++++ +K K +L S +EL ++ +L + + ++SE L E +
Sbjct: 852 MATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQL 911
Query: 439 LHNAVQMKQKDKQ--NISQLEKKLKAEQEARSF-VEKQLMEEKKRKKLEEATAARAVAFA 495
+ N +Q++ K K+ ++ E+++ AE A+ +E + E KK E T A+
Sbjct: 912 IKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 971
Query: 496 AASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKENEKDTEVLM 555
A+ + + L + L+ KL+ + K + E Q L + E +L
Sbjct: 972 HATENK-VKNLTEEMAGLDETIAKLSKEKKALQ------ETHQQTLDDLQAEEDKVNILT 1024
Query: 556 SALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKI 614
A + ++ + LE SL E ++++DL A + L++AQ + + + + L +K+
Sbjct: 1025 KAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKL 1083
Score = 51.6 bits (122), Expect = 2e-06
Identities = 91/480 (18%), Positives = 192/480 (40%), Gaps = 68/480 (14%)
Query: 180 LRKQKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPA 239
L Q K E Q L L ++ LQ EA E ++ L + D+ + +
Sbjct: 1255 LEDQVSELKTKEEEQQRLINDLTAQRARLQT---EAGEYSRQLDEKDALV-----SQLSR 1306
Query: 240 NKKLSTT-LPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRL 298
+K+ ST + E++++ + + K K+A H L + + D + +Y E L
Sbjct: 1307 SKQASTQQIEELKHQLEEETKAKNALAHALQSSRH------DCDLLREQYEEEQEGKAEL 1360
Query: 299 N------NDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEK 352
N V + D+ + + + + + +S +
Sbjct: 1361 QRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKT 1420
Query: 353 KQKCTSKSPSTHKDLMEN-----CIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQEL 407
KQ+ ++ D+ + + Q + L +Q ++ +A+L+AS++ + L
Sbjct: 1421 KQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSL 1480
Query: 408 RSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEAR 467
+++ + + ++ LR+EN+ LQ ++ + + + + I +LEK K ++ +
Sbjct: 1481 STELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEK 1540
Query: 468 SFVEKQLMEEKKRKKLEEATAAR----------AVAFAAASRGECTETL-RNRIRELEAE 516
++ L E + + EE R V A + E + L RN R +E
Sbjct: 1541 CEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETM 1600
Query: 517 GKKLTMDMKVKEDQIR----------ELELKV--------QELRKYKENE---KDTEV-L 554
L +++ + D +R E+E+++ + LR Y+ + K+T++ L
Sbjct: 1601 QSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHL 1660
Query: 555 MSALSAMQDKTQHL------ENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIK 608
AL +D + L N L AE +L++ L +R +IA+ ++L + ++
Sbjct: 1661 DDALRGQEDLKEQLAIVERRANLLQAEIE---ELWATLEQTERSRKIAEQELLDASERVQ 1717
Score = 49.3 bits (116), Expect = 1e-05
Identities = 108/537 (20%), Positives = 199/537 (37%), Gaps = 114/537 (21%)
Query: 185 EVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKKLS 244
++ KE + + QQ L LQ +E + K ++ + G + KKL
Sbjct: 994 KLSKEKKALQETHQQTLDD----LQAEEDKVNILTKAKTKLEQQV-DDLEGSLEQEKKLR 1048
Query: 245 TTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSK-------- 296
L + + +G K A++ + + N+ Q +D K+++ E+ +++ SK
Sbjct: 1049 MDLERAKRKLEGDLKL--AQESTMDMENDK--QQLDEKLEKKEFEISNLISKIEDEQAVE 1104
Query: 297 ----RLNNDLVGSTENLLKEDSCTASS--KNYKNASGVVNSSPRSHSATNGSIPSSSSKN 350
+ +L E L +E +S K K S + + ++S++
Sbjct: 1105 IQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQV 1164
Query: 351 EKKQKCTSKSPSTHKDLMENCIPNNQL------SKPDALVRLEQDIKKLKADLQASRQVE 404
E +K ++ +DL E + + + D++ L + I L+ Q + +
Sbjct: 1165 ELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEK 1224
Query: 405 QELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQL-------- 456
EL+ + LSS I G L + L++++ +++ ++ I+ L
Sbjct: 1225 SELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQ 1284
Query: 457 -----------EKKLKAEQEARS-FVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTE 504
EK Q +RS Q +EE K + EE A A+A A S +
Sbjct: 1285 TEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCD 1344
Query: 505 TLR------------------------------------NRIRELEAEGKKLTMDMKVKE 528
LR R ELE KKL ++ E
Sbjct: 1345 LLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAE 1404
Query: 529 DQIRELELKVQELRKYKEN-EKDTEVLM-------SALSAMQDKTQHLENSLS------A 574
+ + + K L K K+ + + E LM +A +A+ K ++ + LS
Sbjct: 1405 EHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYE 1464
Query: 575 ETRIKL------------DLF---SALGDAKRQLEIAQGQILQKDQEIKDLKQKIAE 616
ET+ +L +LF + ++ QLE + + QEI DL ++IAE
Sbjct: 1465 ETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAE 1521
Score = 48.1 bits (113), Expect = 3e-05
Identities = 98/499 (19%), Positives = 202/499 (40%), Gaps = 101/499 (20%)
Query: 170 FKSYVSYKMRLRKQKEVQKENEFYMQ----LLQQALPPEQQM--LQKQEKEAE----EAA 219
FK Y+ L + + +++EN+ Q L +Q +Q+ L+K +K+ E E
Sbjct: 1485 FKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQ 1544
Query: 220 KGLPDMDSSILIHHNGGIPANKKLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPV 279
L + ++S L H G I ++ L +++ K +KD + L N+ +++ +
Sbjct: 1545 AALEEAEAS-LEHEEGKI---LRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETM 1600
Query: 280 DSKIQ-EIEYMENHIN-SKRLNNDLVGSTENLLKEDSCTASS-KNYKNASGVVNSSPRSH 336
S + EI + + K++ DL L + A S +NY+N G++ +
Sbjct: 1601 QSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKET---- 1656
Query: 337 SATNGSIPSSSSKNEKKQKCTSKSPSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKAD 396
QL DAL R ++D+K+ A
Sbjct: 1657 ---------------------------------------QLHLDDAL-RGQEDLKEQLAI 1676
Query: 397 LQASRQVEQ-ELRSQISSLSSTERGIRSEMGQLRQENE---LLQNKLHNAVQMKQKDKQN 452
++ + Q E+ ++L TER + +L +E LL + + + K+K + +
Sbjct: 1677 VERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLEND 1736
Query: 453 ISQLEKKLK--------AEQEARSFVEKQLMEEKKRKKLEEATA---------------- 488
+SQL+ +++ AE++A+ + M ++ KK ++ +A
Sbjct: 1737 VSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDL 1796
Query: 489 ----ARAVAFAAASRGECTETLRNRIRELEAE-------GKKLTMDMKVKEDQIRELELK 537
A A + + L R+RELE E + ++ E +++EL +
Sbjct: 1797 QHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQ 1856
Query: 538 VQELRKYKENEKD-TEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIA 596
+E RK +D + L + + + + + + E +A L L +A+ + +IA
Sbjct: 1857 TEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIA 1916
Query: 597 QGQILQKDQEIKDLKQKIA 615
+ Q+ + + +++ KI+
Sbjct: 1917 ESQVNKLRVKSREVHTKIS 1935
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 62.0 bits (149), Expect = 2e-09
Identities = 86/472 (18%), Positives = 202/472 (42%), Gaps = 52/472 (11%)
Query: 180 LRKQKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPD-----MDSSILIHHN 234
L+K++ ++K+ + + ++ + +++Q++ + + + L D D + L +
Sbjct: 194 LKKERALRKDEASKITIWKE----QYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQD 249
Query: 235 GGIPANKKLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHIN 294
+ L E ++ E ++ AK+ L + + ++ IE + +N
Sbjct: 250 SSSRTGEPCVAELTEENFQRLHAEHERQAKELFL------LRKTLEEMELRIETQKQTLN 303
Query: 295 SKRLNNDLVGSTENLLKED--SCTASSKNYKNASGVVNSSPRSH---SATNGSIPSSSSK 349
++ ++ + +L+ S A+ ++++ + + H S +S
Sbjct: 304 AR---DESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML 360
Query: 350 NEKKQKCTSKSPSTHKDLMENCIPNNQLSKPDALVR----LEQDIKKLKADLQASRQVEQ 405
E+ + +P + K + + SK ++ R LE++I+ LK++ S + +
Sbjct: 361 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE 420
Query: 406 ELRSQISSLSSTERGIRSEMGQLRQE-----NEL--LQNKLHNAVQMKQKDKQNISQLEK 458
E Q+ S + +++++GQ++QE EL LQ KL KQ+I L++
Sbjct: 421 EEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKE 480
Query: 459 KLKAEQEARSFV------------EKQLMEEKKRKKLEEATAARAV-AFAAASRGECTET 505
L A+++ + + EK+ M KK K++++ + A + +
Sbjct: 481 SLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDV 540
Query: 506 LRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKEN-EKDTEVLMSALSAMQDK 564
++ L+ + + L ++ KE Q+ L+ +V+ L+ N + L AL+ +
Sbjct: 541 KERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERT 600
Query: 565 TQHLENSLSAETRIK---LDLFSA-LGDAKRQLEIAQGQILQKDQEIKDLKQ 612
+ L+ + R K +D + L D K ++ + QG + +K+ + DLK+
Sbjct: 601 IERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKE 652
Score = 46.2 bits (108), Expect = 1e-04
Identities = 83/426 (19%), Positives = 170/426 (39%), Gaps = 50/426 (11%)
Query: 197 LQQALPPEQQMLQKQEKEAEEAA--KG-----LPDMDSSILIHHNGGIPANKKLSTTLPE 249
L+ L ++ ML K+ K+ ++ A KG + D+ + + KK+ +
Sbjct: 499 LRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQ 558
Query: 250 IEYREKGKEKDKDAKKHNLG--INNNNILQPVDSKIQEIEYMENHINSKRLNNDLVGSTE 307
+ +EK K+ K N + L ++ + E E + +R +
Sbjct: 559 LRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQR-------DRD 611
Query: 308 NLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPSTHKDL 367
K++ K+ K+ V+ S S+ + K+ + S KD
Sbjct: 612 EREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASL-----LDLKEHASSLASSGLKKDS 666
Query: 368 MENCIPNNQLSKPDALVRLEQDIKKL-KADLQASRQVEQELRSQISSLSSTERGIRSEMG 426
+ K + +++E +KK +A L+A + E+ +I L + E
Sbjct: 667 RLKTLEIALEQKKEECLKMESQLKKAHEAALEA--RASPEMSDRIQHLEREITRYKDESS 724
Query: 427 QLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEA 486
+ + E + L L K + I++LE+++K + K++ K ++++E+
Sbjct: 725 KAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQN-------KKVANLKHKEQVEKK 777
Query: 487 TAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKE 546
+A+ + E R R L ++L ++ K+D+I ELE + LR+ +
Sbjct: 778 KSAQML-----------EEARRREDNLNDSSQQLQDSLRKKDDRIEELE---EALRESVQ 823
Query: 547 NEKDTE-VLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQ 605
+ E VL SA + + +E L A ++K +L S K +L Q + +K+
Sbjct: 824 ITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELES----MKAKLSSTQQSLAEKET 879
Query: 606 EIKDLK 611
+ +L+
Sbjct: 880 HLTNLR 885
Score = 44.7 bits (104), Expect = 3e-04
Identities = 78/419 (18%), Positives = 166/419 (39%), Gaps = 44/419 (10%)
Query: 184 KEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKKL 243
K++ E + +LQ+ + Q+ L+ +EK+ + + + + + L
Sbjct: 535 KDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEAL 594
Query: 244 STTLPEIEYREKGKEKDKDAKKHNLGINNNNI-------------LQPVDSKIQEIEYME 290
+ IE ++ +++D+ K+ + ++ L ++ + +++
Sbjct: 595 AEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHA 654
Query: 291 NHINSKRLNNDLVGSTENLL---KEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSS 347
+ + S L D T + K++ C K A + R+ + I
Sbjct: 655 SSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEA-RASPEMSDRIQHLE 713
Query: 348 SKNEKKQKCTSKSPSTHKDLMENC--IPNNQLSKPDALVRLEQDIK---KLKADLQASRQ 402
+ + + +SK+ + L+E + N + K + LE+ +K K A+L+ Q
Sbjct: 714 REITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQ 773
Query: 403 VEQELRSQ-ISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLK 461
VE++ +Q + E + QL+ +++ + ++ Q ++ E L
Sbjct: 774 VEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLA 833
Query: 462 AEQEARSFVEKQLME-----EKKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAE 516
E+ AR+ EKQ+ E EK +++LE A + + + E + L AE
Sbjct: 834 QEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKE------THLTNLRAE 887
Query: 517 GKKLTMDMKVKEDQIRELELKVQELRKYKENEKDTEVLMSALSAMQDKTQHLENSLSAE 575
+K ++ LE+K QE +EKD + + LS+ + KTQ +L E
Sbjct: 888 RRKHLEEV---------LEMK-QEALLAAISEKDANIALLELSSSKKKTQEEVAALKRE 936
Score = 40.0 bits (92), Expect = 0.007
Identities = 45/244 (18%), Positives = 108/244 (44%), Gaps = 38/244 (15%)
Query: 387 EQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRS--EMGQLRQENELLQNKLHNAVQ 444
E+ K+L + ++E + +Q +L++ + I+ EM Q + + + H +
Sbjct: 275 ERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTR 334
Query: 445 MKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTE 504
+ + ++ LE L+ +++ S + +++ ++ + ++ +A+ +
Sbjct: 335 RLAEAEMHVHHLESLLEQKEKENSMLREEM--HRRFENAPDSAKTKALQTVIEMKDSKIS 392
Query: 505 TLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQEL----RKYKENE----------KD 550
++ +R+LE E + L + + ++ RE E+K E+ K+ +N+ KD
Sbjct: 393 SMERGLRDLEEEIQMLKSNGALSTEE-REEEMKQMEVYRSHSKFMKNKIGQVKQELSRKD 451
Query: 551 TEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDL 610
TE+L A+Q K + L N S D+K+ +E+ + + K+Q L
Sbjct: 452 TELL-----ALQTKLETLTNQFS--------------DSKQHIEVLKESLTAKEQRAAIL 492
Query: 611 KQKI 614
+ ++
Sbjct: 493 QTEV 496
Score = 37.4 bits (85), Expect = 0.045
Identities = 71/377 (18%), Positives = 149/377 (39%), Gaps = 100/377 (26%)
Query: 339 TNGSIPSSSSKNEKKQKCTSKSPSTHKDLMENCIPN--NQLSKPDA-LVRLEQDIKKLKA 395
+NG++ + + E KQ +S H M+N I +LS+ D L+ L+ ++ L
Sbjct: 410 SNGALSTEEREEEMKQMEVYRS---HSKFMKNKIGQVKQELSRKDTELLALQTKLETLTN 466
Query: 396 DLQASRQVEQELRSQISSLSSTERGIRSEMGQLR---QENELLQNK-------------- 438
S+Q + L+ +++ +++E+ LR +E E + NK
Sbjct: 467 QFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGT 526
Query: 439 ----LHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEA------TA 488
+H+ M ++ ++ L+KK++ QE EKQ+ K+R K +A TA
Sbjct: 527 QAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTA 586
Query: 489 ARAVAFAAASRGECTETLRNR------------------IRELEAEGKKLTMDMKVKE-- 528
+ A A + E L+ + +++L+ + L D+ KE
Sbjct: 587 LTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEAS 646
Query: 529 -------------------DQIRELELKVQE-----LRKYKENEKDTEVLMSALSA--MQ 562
+++ LE+ +++ L+ + +K E + A ++ M
Sbjct: 647 LLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMS 706
Query: 563 DKTQHLENSLS--------AETRI-------------KLDLFSALGDAKRQLEIAQGQIL 601
D+ QHLE ++ A+ + K D + + +RQ++ ++
Sbjct: 707 DRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVA 766
Query: 602 QKDQEIKDLKQKIAEVM 618
+ + K+K A+++
Sbjct: 767 NLKHKEQVEKKKSAQML 783
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.130 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,132,319
Number of Sequences: 37866
Number of extensions: 1046234
Number of successful extensions: 14114
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 283
Number of HSP's successfully gapped in prelim test: 1067
Number of HSP's that attempted gapping in prelim test: 7947
Number of HSP's gapped (non-prelim): 4651
length of query: 664
length of database: 18,247,518
effective HSP length: 109
effective length of query: 555
effective length of database: 14,120,124
effective search space: 7836668820
effective search space used: 7836668820
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.