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Search of human proteins with 31542652
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31542652 coiled-coil domain containing 94 [Homo sapiens]
(323 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31542652 coiled-coil domain containing 94 [Homo sapiens] 652 0.0
gi|13540614 coiled-coil domain containing 130 [Homo sapiens] 95 7e-20
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens] 61 2e-09
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] 53 3e-07
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens] 53 3e-07
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens] 53 3e-07
gi|56549694 enabled homolog isoform a [Homo sapiens] 50 2e-06
gi|39930375 enabled homolog isoform b [Homo sapiens] 50 2e-06
gi|148746195 trichohyalin [Homo sapiens] 48 1e-05
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 47 2e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 46 4e-05
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 46 4e-05
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 46 5e-05
gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens] 46 5e-05
gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens] 46 5e-05
gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens] 45 7e-05
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 45 7e-05
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 45 9e-05
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 45 1e-04
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 44 1e-04
gi|58530840 desmoplakin isoform I [Homo sapiens] 44 2e-04
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 44 2e-04
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 44 2e-04
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 44 2e-04
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 44 2e-04
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 44 2e-04
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 44 2e-04
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 44 2e-04
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 44 2e-04
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 44 2e-04
>gi|31542652 coiled-coil domain containing 94 [Homo sapiens]
Length = 323
Score = 652 bits (1681), Expect = 0.0
Identities = 323/323 (100%), Positives = 323/323 (100%)
Query: 1 MSERKVLNKYYPPDFDPSKIPKLKLPKDRQYVVRLMAPFNMRCKTCGEYIYKGKKFNARK 60
MSERKVLNKYYPPDFDPSKIPKLKLPKDRQYVVRLMAPFNMRCKTCGEYIYKGKKFNARK
Sbjct: 1 MSERKVLNKYYPPDFDPSKIPKLKLPKDRQYVVRLMAPFNMRCKTCGEYIYKGKKFNARK 60
Query: 61 ETVQNEVYLGLPIFRFYIKCTRCLAEITFKTDPENTDYTMEHGATRNFQAEKLLEEEEKR 120
ETVQNEVYLGLPIFRFYIKCTRCLAEITFKTDPENTDYTMEHGATRNFQAEKLLEEEEKR
Sbjct: 61 ETVQNEVYLGLPIFRFYIKCTRCLAEITFKTDPENTDYTMEHGATRNFQAEKLLEEEEKR 120
Query: 121 VQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLRQHRLSE 180
VQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLRQHRLSE
Sbjct: 121 VQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLRQHRLSE 180
Query: 181 EERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQPALRPNPTAILDEAPKP 240
EERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQPALRPNPTAILDEAPKP
Sbjct: 181 EERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQPALRPNPTAILDEAPKP 240
Query: 241 KRKVEVWEQSVGSLGSRPPLSRLVVVKKAKADPDCSNGQPQAAPTPGAPQNRKEANPTPL 300
KRKVEVWEQSVGSLGSRPPLSRLVVVKKAKADPDCSNGQPQAAPTPGAPQNRKEANPTPL
Sbjct: 241 KRKVEVWEQSVGSLGSRPPLSRLVVVKKAKADPDCSNGQPQAAPTPGAPQNRKEANPTPL 300
Query: 301 TPGASSLSQLGAYLDSDDSNGSN 323
TPGASSLSQLGAYLDSDDSNGSN
Sbjct: 301 TPGASSLSQLGAYLDSDDSNGSN 323
>gi|13540614 coiled-coil domain containing 130 [Homo sapiens]
Length = 396
Score = 95.1 bits (235), Expect = 7e-20
Identities = 65/232 (28%), Positives = 111/232 (47%), Gaps = 18/232 (7%)
Query: 1 MSERKVLNKYYPPDFDPSKIPKLKLPKDRQ-------------YVVRLMAPFNMRCKTCG 47
M ERK +NKYYPPDF+P K L + ++R P+N+ C C
Sbjct: 1 MGERKGVNKYYPPDFNPEKHGSLNRYHNSHPLRERARKLSQGILIIRFEMPYNIWCDGCK 60
Query: 48 EYIYKGKKFNARKETVQNEVYLGLPIFRFYIKCTRCLAEITFKTDPENTDYTMEHGATRN 107
+I G ++NA K+ V N Y PI+RF +KC C+ I +TDP N DY + GA R
Sbjct: 61 NHIGMGVRYNAEKKKVGN--YYTTPIYRFRMKCHLCVNYIEMQTDPANCDYVIVSGAQRK 118
Query: 108 FQAEKLLEEEEKRVQKEREDEEL-NNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAH 166
+ + + E+ + + ++L + M LE+ D + L L +++ + A
Sbjct: 119 EERWDMADNEQVLTTEHEKKQKLETDAMFRLEHGEADRSTLKKALPTLSHIQE--AQSAW 176
Query: 167 VDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAA 218
D A+ R E+++ QEE+E++ A + + L+ +++ + + A
Sbjct: 177 KDDFALNSMLRRRFREKKKAIQEEEERDQALQAKASLTIPLVPETEDDRKLA 228
>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
Length = 1312
Score = 60.8 bits (146), Expect = 2e-09
Identities = 55/209 (26%), Positives = 85/209 (40%), Gaps = 14/209 (6%)
Query: 106 RNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQA 165
R + + L EE+R Q ERE E K LE + + +L+ ++ + LK L Q+Q
Sbjct: 428 RRLEDMQALRREEERRQAEREQEYKR---KQLEEQRQSERLQRQLQQEHAYLKSLQQQQQ 484
Query: 166 HVDFEAMLRQHRLSEEERR-----RQQQEEDEQETAALLEEARKRRLLEDS----DSEDE 216
+ +Q L + + R D+ A +EE + ++S
Sbjct: 485 QQQLQKQQQQQLLPGDRKPLYHYGRGMNPADKPAWAREVEERTRMNKQQNSPLAKSKPGS 544
Query: 217 AAPSPLQPALRPNPTAILDEAPKPKRKVEVWEQSVGSLGSRPPLSRLVVVKKAKADPDCS 276
P P P P P L + P +R VE E SL +P +R + A DPD +
Sbjct: 545 TGPEPPIPQASPGPPGPLSQTPPMQRPVEPQEGPHKSLQDQP--TRNLAAFPASHDPDPA 602
Query: 277 NGQPQAAPTPGAPQNRKEANPTPLTPGAS 305
P A P+ R+ ++PT PG S
Sbjct: 603 IPAPTATPSARGAVIRQNSDPTSEGPGPS 631
Score = 38.5 bits (88), Expect = 0.008
Identities = 24/71 (33%), Positives = 40/71 (56%), Gaps = 5/71 (7%)
Query: 142 KDSKLEMEVLENLQELKDLNQR--QAHVDFEAMLRQHRLSE---EERRRQQQEEDEQETA 196
+++K E L+ Q+L+ QR +AH+ RQ R+ E E RR ++Q+ E+E
Sbjct: 360 QENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQR 419
Query: 197 ALLEEARKRRL 207
L E+ ++RRL
Sbjct: 420 KLQEKEQQRRL 430
Score = 29.3 bits (64), Expect = 4.9
Identities = 40/177 (22%), Positives = 77/177 (43%), Gaps = 27/177 (15%)
Query: 101 EHGATRNFQAEKLLEEEEKRVQKERED--EELNNPMKVLENRTKDSKLEMEVLENLQELK 158
E + N E L E R+Q+E + E L ++ + + +D + ++ L
Sbjct: 338 EPSSIMNVPGESTLRREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHL------- 390
Query: 159 DLNQRQAHVDFEAMLRQHRLSEEERRRQQ---QEEDEQ-----ETAALLEEARKRRLLED 210
L+QRQ ++ E + R+ E++RR ++ +E EQ + AL E +R+ +
Sbjct: 391 -LHQRQRRIE-EQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAERE 448
Query: 211 SD-----SEDEAAPSPLQPALRPNPTAILDEAPKPKRKVEVWEQSVGSL--GSRPPL 260
+ E++ LQ L+ A L + +++ ++ +Q L G R PL
Sbjct: 449 QEYKRKQLEEQRQSERLQRQLQ-QEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPL 504
>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
Length = 1303
Score = 53.1 bits (126), Expect = 3e-07
Identities = 57/227 (25%), Positives = 86/227 (37%), Gaps = 30/227 (13%)
Query: 106 RNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQA 165
R + + L EE+R Q ERE E K LE + + +L+ ++ + LK L Q+Q
Sbjct: 428 RRLEDMQALRREEERRQAEREQEYKR---KQLEEQRQSERLQRQLQQEHAYLKSLQQQQQ 484
Query: 166 HVDFEAMLRQHRLSEEERR-----RQQQEEDEQETAALLEEARKRRLLEDS----DSEDE 216
+ +Q L + + R D+ A +EE + ++S
Sbjct: 485 QQQLQKQQQQQLLPGDRKPLYHYGRGMNPADKPAWAREVEERTRMNKQQNSPLAKSKPGS 544
Query: 217 AAPSPLQPALRPNPTAILDEAPKPKRKVEVWEQSVGSL-GSRPPL--------------- 260
P P P P P L + P +R VE E SL R PL
Sbjct: 545 TGPEPPIPQASPGPPGPLSQTPPMQRPVEPQEGPHKSLVAHRVPLKPYAAPVPRSQSLQD 604
Query: 261 --SRLVVVKKAKADPDCSNGQPQAAPTPGAPQNRKEANPTPLTPGAS 305
+R + A DPD + P A P+ R+ ++PT PG S
Sbjct: 605 QPTRNLAAFPASHDPDPAIPAPTATPSARGAVIRQNSDPTSEGPGPS 651
Score = 41.2 bits (95), Expect = 0.001
Identities = 40/203 (19%), Positives = 84/203 (41%), Gaps = 30/203 (14%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLE-MEVLENLQELKDLNQRQAHV 167
Q ++ +EE+++ ++ E + + L+ + + +LE M+ L +E + + Q +
Sbjct: 393 QRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYK 452
Query: 168 DFEAMLRQHRLSEEERRRQQQEE------DEQETAALLEEARKRRLLEDSDSEDEAAPSP 221
L + R SE +R+ QQE +Q+ L++ ++++LL
Sbjct: 453 --RKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRG 510
Query: 222 LQPALRPNPTAILDEAPKPKRKVE--VWEQSVGSLGSRPPLSRLVVVKKAKADPDCSNGQ 279
+ PA +P ++E + ++ + + GS G PP+
Sbjct: 511 MNPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPI------------------- 551
Query: 280 PQAAPTPGAPQNRKEANPTPLTP 302
PQA+P P P ++ P+ P
Sbjct: 552 PQASPGPPGPLSQTPPMQRPVEP 574
Score = 38.5 bits (88), Expect = 0.008
Identities = 24/71 (33%), Positives = 40/71 (56%), Gaps = 5/71 (7%)
Query: 142 KDSKLEMEVLENLQELKDLNQR--QAHVDFEAMLRQHRLSE---EERRRQQQEEDEQETA 196
+++K E L+ Q+L+ QR +AH+ RQ R+ E E RR ++Q+ E+E
Sbjct: 360 QENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQR 419
Query: 197 ALLEEARKRRL 207
L E+ ++RRL
Sbjct: 420 KLQEKEQQRRL 430
Score = 29.3 bits (64), Expect = 4.9
Identities = 40/177 (22%), Positives = 77/177 (43%), Gaps = 27/177 (15%)
Query: 101 EHGATRNFQAEKLLEEEEKRVQKERED--EELNNPMKVLENRTKDSKLEMEVLENLQELK 158
E + N E L E R+Q+E + E L ++ + + +D + ++ L
Sbjct: 338 EPSSIMNVPGESTLRREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHL------- 390
Query: 159 DLNQRQAHVDFEAMLRQHRLSEEERRRQQ---QEEDEQ-----ETAALLEEARKRRLLED 210
L+QRQ ++ E + R+ E++RR ++ +E EQ + AL E +R+ +
Sbjct: 391 -LHQRQRRIE-EQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAERE 448
Query: 211 SD-----SEDEAAPSPLQPALRPNPTAILDEAPKPKRKVEVWEQSVGSL--GSRPPL 260
+ E++ LQ L+ A L + +++ ++ +Q L G R PL
Sbjct: 449 QEYKRKQLEEQRQSERLQRQLQ-QEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPL 504
>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
Length = 1332
Score = 53.1 bits (126), Expect = 3e-07
Identities = 57/227 (25%), Positives = 86/227 (37%), Gaps = 30/227 (13%)
Query: 106 RNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQA 165
R + + L EE+R Q ERE E K LE + + +L+ ++ + LK L Q+Q
Sbjct: 428 RRLEDMQALRREEERRQAEREQEYKR---KQLEEQRQSERLQRQLQQEHAYLKSLQQQQQ 484
Query: 166 HVDFEAMLRQHRLSEEERR-----RQQQEEDEQETAALLEEARKRRLLEDS----DSEDE 216
+ +Q L + + R D+ A +EE + ++S
Sbjct: 485 QQQLQKQQQQQLLPGDRKPLYHYGRGMNPADKPAWAREVEERTRMNKQQNSPLAKSKPGS 544
Query: 217 AAPSPLQPALRPNPTAILDEAPKPKRKVEVWEQSVGSL-GSRPPL--------------- 260
P P P P P L + P +R VE E SL R PL
Sbjct: 545 TGPEPPIPQASPGPPGPLSQTPPMQRPVEPQEGPHKSLVAHRVPLKPYAAPVPRSQSLQD 604
Query: 261 --SRLVVVKKAKADPDCSNGQPQAAPTPGAPQNRKEANPTPLTPGAS 305
+R + A DPD + P A P+ R+ ++PT PG S
Sbjct: 605 QPTRNLAAFPASHDPDPAIPAPTATPSARGAVIRQNSDPTSEGPGPS 651
Score = 41.2 bits (95), Expect = 0.001
Identities = 40/203 (19%), Positives = 84/203 (41%), Gaps = 30/203 (14%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLE-MEVLENLQELKDLNQRQAHV 167
Q ++ +EE+++ ++ E + + L+ + + +LE M+ L +E + + Q +
Sbjct: 393 QRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYK 452
Query: 168 DFEAMLRQHRLSEEERRRQQQEE------DEQETAALLEEARKRRLLEDSDSEDEAAPSP 221
L + R SE +R+ QQE +Q+ L++ ++++LL
Sbjct: 453 --RKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRG 510
Query: 222 LQPALRPNPTAILDEAPKPKRKVE--VWEQSVGSLGSRPPLSRLVVVKKAKADPDCSNGQ 279
+ PA +P ++E + ++ + + GS G PP+
Sbjct: 511 MNPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPI------------------- 551
Query: 280 PQAAPTPGAPQNRKEANPTPLTP 302
PQA+P P P ++ P+ P
Sbjct: 552 PQASPGPPGPLSQTPPMQRPVEP 574
Score = 38.5 bits (88), Expect = 0.008
Identities = 24/71 (33%), Positives = 40/71 (56%), Gaps = 5/71 (7%)
Query: 142 KDSKLEMEVLENLQELKDLNQR--QAHVDFEAMLRQHRLSE---EERRRQQQEEDEQETA 196
+++K E L+ Q+L+ QR +AH+ RQ R+ E E RR ++Q+ E+E
Sbjct: 360 QENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQR 419
Query: 197 ALLEEARKRRL 207
L E+ ++RRL
Sbjct: 420 KLQEKEQQRRL 430
Score = 29.3 bits (64), Expect = 4.9
Identities = 40/177 (22%), Positives = 77/177 (43%), Gaps = 27/177 (15%)
Query: 101 EHGATRNFQAEKLLEEEEKRVQKERED--EELNNPMKVLENRTKDSKLEMEVLENLQELK 158
E + N E L E R+Q+E + E L ++ + + +D + ++ L
Sbjct: 338 EPSSIMNVPGESTLRREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHL------- 390
Query: 159 DLNQRQAHVDFEAMLRQHRLSEEERRRQQ---QEEDEQ-----ETAALLEEARKRRLLED 210
L+QRQ ++ E + R+ E++RR ++ +E EQ + AL E +R+ +
Sbjct: 391 -LHQRQRRIE-EQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAERE 448
Query: 211 SD-----SEDEAAPSPLQPALRPNPTAILDEAPKPKRKVEVWEQSVGSL--GSRPPL 260
+ E++ LQ L+ A L + +++ ++ +Q L G R PL
Sbjct: 449 QEYKRKQLEEQRQSERLQRQLQ-QEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPL 504
>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
Length = 1295
Score = 53.1 bits (126), Expect = 3e-07
Identities = 57/227 (25%), Positives = 86/227 (37%), Gaps = 30/227 (13%)
Query: 106 RNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQA 165
R + + L EE+R Q ERE E K LE + + +L+ ++ + LK L Q+Q
Sbjct: 428 RRLEDMQALRREEERRQAEREQEYKR---KQLEEQRQSERLQRQLQQEHAYLKSLQQQQQ 484
Query: 166 HVDFEAMLRQHRLSEEERR-----RQQQEEDEQETAALLEEARKRRLLEDS----DSEDE 216
+ +Q L + + R D+ A +EE + ++S
Sbjct: 485 QQQLQKQQQQQLLPGDRKPLYHYGRGMNPADKPAWAREVEERTRMNKQQNSPLAKSKPGS 544
Query: 217 AAPSPLQPALRPNPTAILDEAPKPKRKVEVWEQSVGSL-GSRPPL--------------- 260
P P P P P L + P +R VE E SL R PL
Sbjct: 545 TGPEPPIPQASPGPPGPLSQTPPMQRPVEPQEGPHKSLVAHRVPLKPYAAPVPRSQSLQD 604
Query: 261 --SRLVVVKKAKADPDCSNGQPQAAPTPGAPQNRKEANPTPLTPGAS 305
+R + A DPD + P A P+ R+ ++PT PG S
Sbjct: 605 QPTRNLAAFPASHDPDPAIPAPTATPSARGAVIRQNSDPTSEGPGPS 651
Score = 41.2 bits (95), Expect = 0.001
Identities = 40/203 (19%), Positives = 84/203 (41%), Gaps = 30/203 (14%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLE-MEVLENLQELKDLNQRQAHV 167
Q ++ +EE+++ ++ E + + L+ + + +LE M+ L +E + + Q +
Sbjct: 393 QRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYK 452
Query: 168 DFEAMLRQHRLSEEERRRQQQEE------DEQETAALLEEARKRRLLEDSDSEDEAAPSP 221
L + R SE +R+ QQE +Q+ L++ ++++LL
Sbjct: 453 --RKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRG 510
Query: 222 LQPALRPNPTAILDEAPKPKRKVE--VWEQSVGSLGSRPPLSRLVVVKKAKADPDCSNGQ 279
+ PA +P ++E + ++ + + GS G PP+
Sbjct: 511 MNPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPI------------------- 551
Query: 280 PQAAPTPGAPQNRKEANPTPLTP 302
PQA+P P P ++ P+ P
Sbjct: 552 PQASPGPPGPLSQTPPMQRPVEP 574
Score = 38.5 bits (88), Expect = 0.008
Identities = 24/71 (33%), Positives = 40/71 (56%), Gaps = 5/71 (7%)
Query: 142 KDSKLEMEVLENLQELKDLNQR--QAHVDFEAMLRQHRLSE---EERRRQQQEEDEQETA 196
+++K E L+ Q+L+ QR +AH+ RQ R+ E E RR ++Q+ E+E
Sbjct: 360 QENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQR 419
Query: 197 ALLEEARKRRL 207
L E+ ++RRL
Sbjct: 420 KLQEKEQQRRL 430
Score = 29.3 bits (64), Expect = 4.9
Identities = 40/177 (22%), Positives = 77/177 (43%), Gaps = 27/177 (15%)
Query: 101 EHGATRNFQAEKLLEEEEKRVQKERED--EELNNPMKVLENRTKDSKLEMEVLENLQELK 158
E + N E L E R+Q+E + E L ++ + + +D + ++ L
Sbjct: 338 EPSSIMNVPGESTLRREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHL------- 390
Query: 159 DLNQRQAHVDFEAMLRQHRLSEEERRRQQ---QEEDEQ-----ETAALLEEARKRRLLED 210
L+QRQ ++ E + R+ E++RR ++ +E EQ + AL E +R+ +
Sbjct: 391 -LHQRQRRIE-EQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAERE 448
Query: 211 SD-----SEDEAAPSPLQPALRPNPTAILDEAPKPKRKVEVWEQSVGSL--GSRPPL 260
+ E++ LQ L+ A L + +++ ++ +Q L G R PL
Sbjct: 449 QEYKRKQLEEQRQSERLQRQLQ-QEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPL 504
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 50.4 bits (119), Expect = 2e-06
Identities = 63/229 (27%), Positives = 86/229 (37%), Gaps = 35/229 (15%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLE-MEVLENLQELKDLNQRQAHV 167
+ E+L E +R + ERE E + + R + +LE E LE + L +RQ +
Sbjct: 167 ERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERL----ERQERL 222
Query: 168 DFEAMLRQ--HRLSEEERRRQQQEEDEQETAALLEEARKRRL----------------LE 209
D E RQ RL ER RQ++E EQ LE R+RR+ L
Sbjct: 223 DRERQERQERERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLG 282
Query: 210 DSDSEDEAAPSPLQPALRPNPTAIL--DEAPKPKRKVEVWEQSVGSLGSRPPLSRLVVVK 267
DS + + + QPA P+ I+ AP P + PP
Sbjct: 283 DSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPP-------G 335
Query: 268 KAKADPDCSNGQPQAAPTPGAPQNRKEANPTPLTPGASSLSQLGAYLDS 316
P S G P P P P + P P P A L G +L S
Sbjct: 336 PPPPPPLPSTGPPPPPPPPPLP---NQVPPPPPPPPAPPLPASGFFLAS 381
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 50.4 bits (119), Expect = 2e-06
Identities = 63/229 (27%), Positives = 86/229 (37%), Gaps = 35/229 (15%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLE-MEVLENLQELKDLNQRQAHV 167
+ E+L E +R + ERE E + + R + +LE E LE + L +RQ +
Sbjct: 167 ERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERL----ERQERL 222
Query: 168 DFEAMLRQ--HRLSEEERRRQQQEEDEQETAALLEEARKRRL----------------LE 209
D E RQ RL ER RQ++E EQ LE R+RR+ L
Sbjct: 223 DRERQERQERERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLG 282
Query: 210 DSDSEDEAAPSPLQPALRPNPTAIL--DEAPKPKRKVEVWEQSVGSLGSRPPLSRLVVVK 267
DS + + + QPA P+ I+ AP P + PP
Sbjct: 283 DSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPP-------G 335
Query: 268 KAKADPDCSNGQPQAAPTPGAPQNRKEANPTPLTPGASSLSQLGAYLDS 316
P S G P P P P + P P P A L G +L S
Sbjct: 336 PPPPPPLPSTGPPPPPPPPPLP---NQVPPPPPPPPAPPLPASGFFLAS 381
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 47.8 bits (112), Expect = 1e-05
Identities = 37/151 (24%), Positives = 76/151 (50%), Gaps = 20/151 (13%)
Query: 109 QAEKLLEEE------EKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQ 162
+ E+LL EE ++R ++ RE+EEL + L ++++ E+ ++ ++L Q
Sbjct: 1029 EEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQ 1088
Query: 163 RQAHVDFEAMLRQ----HRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAA 218
+ E +LR+ R E ER+ +++EE +QE LL E R++R ++ + +
Sbjct: 1089 EE-----EQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYRE- 1142
Query: 219 PSPLQPALRPNPTAILDEAPKPKRKVEVWEQ 249
+ ++ +L E P+ +R+ E+ Q
Sbjct: 1143 ----EEEVQQEEEQLLREEPEKRRRQELERQ 1169
Score = 46.6 bits (109), Expect = 3e-05
Identities = 31/106 (29%), Positives = 59/106 (55%), Gaps = 3/106 (2%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD 168
+ EKL EEE +R ++ +E+EE ++ E R ++ + E + + L+ + L ++Q
Sbjct: 256 EEEKLQEEEPQRQRELQEEEEQLRKLERQELR-RERQEEEQQQQRLRREQQLRRKQEEER 314
Query: 169 FEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSE 214
E ++ R ++ERR QQ+E EQ+ EE R+++L + + E
Sbjct: 315 REQ--QEERREQQERREQQEERREQQLRREQEERREQQLRREQEEE 358
Score = 46.6 bits (109), Expect = 3e-05
Identities = 39/145 (26%), Positives = 70/145 (48%), Gaps = 20/145 (13%)
Query: 111 EKLLEEE------EKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQ 164
E+LL EE ++R +K RE+EEL + L ++ + E ++ +L Q +
Sbjct: 971 EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEE 1030
Query: 165 AHVDFEAMLRQ----HRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPS 220
E +LR+ RL E ER+ +++EE +QE LL E R+ R ++ + +
Sbjct: 1031 -----EQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRK--- 1082
Query: 221 PLQPALRPNPTAILDEAPKPKRKVE 245
+ L+ +L E P+ +R+ E
Sbjct: 1083 --EEELQQEEEQLLREEPEKRRRQE 1105
Score = 45.4 bits (106), Expect = 7e-05
Identities = 30/108 (27%), Positives = 57/108 (52%), Gaps = 1/108 (0%)
Query: 114 LEEEEKRVQK-EREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAM 172
LE+EE+R Q+ +RE+ E ++L++ ++ + + ++ QE ++ ++ +
Sbjct: 610 LEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLE 669
Query: 173 LRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPS 220
R R EEERR Q+ E+EQE A ++R + +SE +A S
Sbjct: 670 QRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQS 717
Score = 44.7 bits (104), Expect = 1e-04
Identities = 31/112 (27%), Positives = 56/112 (50%), Gaps = 14/112 (12%)
Query: 109 QAEKLLEEEEKRVQKE-----REDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQR 163
+ + L EE EKR ++E RE+EE+ + L + + E+ +E ++L Q
Sbjct: 1120 EEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQE 1179
Query: 164 QAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSED 215
+ E +LR+ E+E+RRQ++E +E L + RK+R ++ D
Sbjct: 1180 E-----EQLLRE----EQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSD 1222
Score = 44.3 bits (103), Expect = 1e-04
Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 20/120 (16%)
Query: 109 QAEKLLEEEE-----KRVQKEREDEELNNPMKVLENRTK-------DSKLEMEVLENLQE 156
+ EK LE+E KR Q+ER D+ L + + R K + +L+ E +E L++
Sbjct: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ 612
Query: 157 LKDLNQRQAHVDFEAMLRQHRLS--EEERRRQQQEEDEQETAALLEEARKRRLLEDSDSE 214
+ QR + E RQ L E+E RRQQQ EQ +E R++RL + + E
Sbjct: 613 EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQ------QERREQRLKREEEEE 666
Score = 44.3 bits (103), Expect = 1e-04
Identities = 29/113 (25%), Positives = 55/113 (48%), Gaps = 14/113 (12%)
Query: 111 EKLLEEEEKRVQKE--------------REDEELNNPMKVLENRTKDSKLEMEVLENLQE 156
++LL+EEE+ +Q+E RE+E+L + L ++ + E ++
Sbjct: 903 QQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRK 962
Query: 157 LKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLE 209
K L Q++ + E ++ R E++ R+++E ++E L EE KRR E
Sbjct: 963 DKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQE 1015
Score = 44.3 bits (103), Expect = 1e-04
Identities = 31/114 (27%), Positives = 57/114 (50%), Gaps = 6/114 (5%)
Query: 109 QAEKLLEEE-EKRVQKER-----EDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQ 162
+ E+LL EE EKR ++ER E+EEL + L ++ + E+ +E +++ Q
Sbjct: 1089 EEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ 1148
Query: 163 RQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDE 216
+ + E ++ R E + R+++E ++E L EE KRR + +E
Sbjct: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREE 1202
Score = 43.5 bits (101), Expect = 3e-04
Identities = 30/100 (30%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Query: 115 EEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLR 174
E+EE+R +++ E E +K + +D E E ++ + Q + + E R
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Query: 175 QHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSE 214
+L EEE RR+QQE EQ+ EE R++RL + E
Sbjct: 488 WLKLEEEE-RREQQERREQQLRREQEERREQRLKRQEEEE 526
Score = 43.5 bits (101), Expect = 3e-04
Identities = 33/109 (30%), Positives = 56/109 (51%), Gaps = 6/109 (5%)
Query: 114 LEEEEKRVQKEREDEELNNPMKVL-ENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAM 172
LEEEE+R Q+ER +++L + E R K + E + + L+ + L + Q + +
Sbjct: 491 LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLL 550
Query: 173 LRQHRLSEEERRRQQQEEDEQETA--ALL---EEARKRRLLEDSDSEDE 216
R+ E+ RR+Q+ + EQE LL EE R++RL + + E
Sbjct: 551 KREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLE 599
Score = 43.5 bits (101), Expect = 3e-04
Identities = 34/109 (31%), Positives = 57/109 (52%), Gaps = 18/109 (16%)
Query: 111 EKLLE-EEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDF 169
E+LL+ EEEKR+++ER ++ L + +D L+ E Q LK R+
Sbjct: 547 EQLLKREEEKRLEQERREQRLKRE----QEERRDQLLKREEERRQQRLK----REQEERL 598
Query: 170 EAMLRQH---RLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSED 215
E L++ RL +EERR Q+ + +E E E R+++LL+ + E+
Sbjct: 599 EQRLKREEVERLEQEERREQRLKREEPE------EERRQQLLKSEEQEE 641
Score = 42.0 bits (97), Expect = 7e-04
Identities = 27/107 (25%), Positives = 53/107 (49%), Gaps = 1/107 (0%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD 168
Q ++ L+EEE++++K E +EL + E + + + E ++ +E + Q +
Sbjct: 266 QRQRELQEEEEQLRK-LERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ 324
Query: 169 FEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSED 215
E +Q E++ RR+Q+E EQ+ EE R+ + L E+
Sbjct: 325 QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEE 371
Score = 41.6 bits (96), Expect = 0.001
Identities = 36/119 (30%), Positives = 54/119 (45%), Gaps = 14/119 (11%)
Query: 106 RNFQAEKLLEEEEKRVQK----------EREDEELNNPMKVLENRTKDSKLEMEVLENLQ 155
R Q EEEEK +K + ++EE ++ E + KLE + L +
Sbjct: 231 RERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELR--R 288
Query: 156 ELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSE 214
E ++ Q+Q + E LR R EEERR QQ+E EQ+ +E R+ + L E
Sbjct: 289 ERQEEEQQQQRLRREQQLR--RKQEEERREQQEERREQQERREQQEERREQQLRREQEE 345
Score = 41.6 bits (96), Expect = 0.001
Identities = 43/175 (24%), Positives = 76/175 (43%), Gaps = 26/175 (14%)
Query: 109 QAEKLLEEEEKRVQKERE-------------DEELNNPMKVLENRTKDSKLEMEVLENLQ 155
+ E+L +EEE+ +++ERE D++L + L + + E + +
Sbjct: 932 EEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYR 991
Query: 156 ELKDLNQRQAHVDFEAMLRQ----HRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDS 211
E ++L Q + E +LR+ R E ER+ ++++E +QE LL E R++R L++
Sbjct: 992 EEEELQQEE-----EQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
Query: 212 D----SEDEAAPSPLQPALRPNPTAILDEAPKPKRKVEVWEQSVGSLGSRPPLSR 262
+ E+E Q T E + RK E +Q L P R
Sbjct: 1047 ERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKR 1101
Score = 41.2 bits (95), Expect = 0.001
Identities = 34/113 (30%), Positives = 54/113 (47%), Gaps = 16/113 (14%)
Query: 115 EEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLN----------QRQ 164
EEE +R ++ER ++L + E R + KLE E QE ++ QR
Sbjct: 461 EEETERHEQERRKQQLKRDQEE-ERRERWLKLEEEERREQQERREQQLRREQEERREQRL 519
Query: 165 AHVDFEAMLRQHRLSEEERRRQQQEEDEQ-----ETAALLEEARKRRLLEDSD 212
+ E L+Q SE++ RR+Q+E EQ E L +E R++RL + +
Sbjct: 520 KRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQE 572
Score = 41.2 bits (95), Expect = 0.001
Identities = 29/104 (27%), Positives = 51/104 (49%), Gaps = 5/104 (4%)
Query: 115 EEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLR 174
E E+R++++ E+E L ++ + ++ + E L +E K L Q + +
Sbjct: 513 ERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQE 572
Query: 175 QHR---LSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSED 215
+ R L EE RRQQ+ + EQE LE+ KR +E + E+
Sbjct: 573 ERRDQLLKREEERRQQRLKREQEER--LEQRLKREEVERLEQEE 614
Score = 40.8 bits (94), Expect = 0.002
Identities = 35/154 (22%), Positives = 71/154 (46%), Gaps = 14/154 (9%)
Query: 101 EHGATRNFQAEKLLEEEE--------KRVQKEREDEELNNPMKVLENRTKDSKLEMEVL- 151
E R +A++L EEE+ +R Q++R D++ ++ R + + L
Sbjct: 837 EEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQ 896
Query: 152 ENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDS 211
E L++ + L Q + + R E+ER+ +++E+ +QE LL E R++R ++
Sbjct: 897 EQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQER 956
Query: 212 DSEDEAAPSPLQPALRPNPTAILDEAPKPKRKVE 245
+ + L+ +L E P+ +R+ E
Sbjct: 957 ERQYRK-----DKKLQQKEEQLLGEEPEKRRRQE 985
Score = 40.8 bits (94), Expect = 0.002
Identities = 42/138 (30%), Positives = 64/138 (46%), Gaps = 30/138 (21%)
Query: 109 QAEKLLEEEEKRVQKE----REDEELNNPMK-------------------VLENRTKDSK 145
+ + L EE+EKR Q+ RE+EEL + EN +D+K
Sbjct: 1180 EEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNK 1239
Query: 146 LEMEVLENLQ--ELKD--LNQRQAHVDFEAML--RQHRLSEEERRR-QQQEEDEQETAAL 198
+ + EN Q +L+D L RQ+ D + +L +Q R E+ERRR QQ++ E L
Sbjct: 1240 VYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQL 1299
Query: 199 LEEARKRRLLEDSDSEDE 216
E +K D S++E
Sbjct: 1300 EREEQKEAKRRDRKSQEE 1317
Score = 40.4 bits (93), Expect = 0.002
Identities = 27/100 (27%), Positives = 51/100 (51%), Gaps = 4/100 (4%)
Query: 117 EEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLRQH 176
EEK+ Q+ + + + E R +++ L E E LQE + QR+ + E +
Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEE-EKLQEEEPQRQRELQEEEEQL---R 279
Query: 177 RLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDE 216
+L +E RR++QEE++Q+ E+ +R+ E+ + E
Sbjct: 280 KLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQE 319
Score = 40.4 bits (93), Expect = 0.002
Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Query: 109 QAEKLL-EEEEKRVQKE-----REDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQ 162
+ E+LL EE E R ++E R++EEL + L + + E +E ++L Q
Sbjct: 1059 EEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQ 1118
Query: 163 RQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRR--LLEDSDSEDEAAPS 220
+ + E ++ R E + R+++E ++E L EE KRR LE E+E
Sbjct: 1119 EEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQ 1178
Query: 221 PLQPALRPNPTAILDEAPKPKRKVE 245
+ LR E + R+ E
Sbjct: 1179 EEEQLLREEQEKRRQERERQYREEE 1203
Score = 40.0 bits (92), Expect = 0.003
Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 2/106 (1%)
Query: 106 RNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQA 165
R+F E+ LE EE++ K R D + ++L ++ + E +E + L Q +
Sbjct: 1291 RHFPEEEQLEREEQKEAKRR-DRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQERE 1349
Query: 166 HVDFEAMLRQHRLSEEERRRQQQ-EEDEQETAALLEEARKRRLLED 210
R + EEE R Q+Q + +E L + R+R+ L++
Sbjct: 1350 EQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKE 1395
Score = 39.7 bits (91), Expect = 0.004
Identities = 29/102 (28%), Positives = 53/102 (51%), Gaps = 6/102 (5%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD 168
+ E+L + E + +++ER++EE ++ + K E E E +E ++ +R+ +
Sbjct: 274 EEEQLRKLERQELRRERQEEE-QQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332
Query: 169 FEAMLRQHRLSEEERRRQQ----QEEDEQETAALLEEARKRR 206
E +Q R +EERR QQ QEE+ +E E+ +RR
Sbjct: 333 -ERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERR 373
Score = 39.7 bits (91), Expect = 0.004
Identities = 33/125 (26%), Positives = 60/125 (48%), Gaps = 2/125 (1%)
Query: 86 EITFKTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSK 145
E + + E + +H R Q K E+EE+R +RE+E + + + + K +
Sbjct: 422 EQQLRREQEEERHEQKHEQERREQRLKR-EQEERRDWLKREEETERHEQERRKQQLKRDQ 480
Query: 146 LEMEVLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKR 205
E E E +L++ +R+ E LR+ + E+R ++QEE+E+ L E + R
Sbjct: 481 -EEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR 539
Query: 206 RLLED 210
R E+
Sbjct: 540 REQEE 544
Score = 39.3 bits (90), Expect = 0.005
Identities = 26/109 (23%), Positives = 53/109 (48%), Gaps = 3/109 (2%)
Query: 106 RNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQA 165
R Q E+ E++ +R Q+ER +++L E ++ +L E E +E + ++Q
Sbjct: 327 RREQQEERREQQLRREQEERREQQLRREQ---EEERREQQLRREQEEERREQQLRREQQL 383
Query: 166 HVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSE 214
+ + Q E++ RR+QQ EQ+ + R+++L + + E
Sbjct: 384 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE 432
Score = 38.9 bits (89), Expect = 0.006
Identities = 34/135 (25%), Positives = 62/135 (45%), Gaps = 12/135 (8%)
Query: 86 EITFKTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSK 145
E F+ + + T + R + K+LEEE+ R ++E + L + +D K
Sbjct: 1722 ERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQ---------LRRQERDRK 1772
Query: 146 L-EMEVLENLQELKDLNQRQAHVDF--EAMLRQHRLSEEERRRQQQEEDEQETAALLEEA 202
E E L +E + L +++ F E LRQ R ++ R +Q+ + E L E
Sbjct: 1773 FREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEE 1832
Query: 203 RKRRLLEDSDSEDEA 217
+++RL ++ D + A
Sbjct: 1833 QEQRLRQERDRQYRA 1847
Score = 38.5 bits (88), Expect = 0.008
Identities = 23/100 (23%), Positives = 49/100 (49%), Gaps = 2/100 (2%)
Query: 115 EEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLR 174
E++ +R Q+ R +++L ++ R + + E ++ Q ++ + + E R
Sbjct: 386 EQQLRREQQLRREQQLRREQQL--RREQQLRREQQLRREQQLRREQEEERHEQKHEQERR 443
Query: 175 QHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSE 214
+ RL E+ R+ + E+ET +E RK++L D + E
Sbjct: 444 EQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEE 483
Score = 38.5 bits (88), Expect = 0.008
Identities = 34/151 (22%), Positives = 66/151 (43%), Gaps = 4/151 (2%)
Query: 94 ENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLEN 153
E D ++ R Q K +EE + +RE+ E + E R K + E E +
Sbjct: 573 ERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQ 632
Query: 154 LQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDS 213
L + ++ +R+ + + R+ + E+R ++++EE+ E E +RR E ++
Sbjct: 633 LLKSEEQEERRQ----QQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEE 688
Query: 214 EDEAAPSPLQPALRPNPTAILDEAPKPKRKV 244
E E A ++ + + EA + KV
Sbjct: 689 EQEQARERIKSRIPKWQWQLESEADARQSKV 719
Score = 38.1 bits (87), Expect = 0.011
Identities = 40/171 (23%), Positives = 75/171 (43%), Gaps = 14/171 (8%)
Query: 97 DYTMEHGATRNFQAEKLLEEE------EKRVQKERE---DEELNNPMKVLENRTKDSKLE 147
D E R ++ LEEE +KR ++ERE EE + + LE R + + E
Sbjct: 112 DRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDE 171
Query: 148 MEVLENLQELKDLNQRQAHVDFEAMLRQHRLSE----EERRRQQQEEDEQETAALLEEAR 203
E+ QE ++ +R+A + + H E E+ RR++ E ++ ++ R
Sbjct: 172 -ELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQR 230
Query: 204 KRRLLEDSDSEDEAAPSPLQPALRPNPTAILDEAPKPKRKVEVWEQSVGSL 254
+ R E+E + LR + +E P+ +R+++ E+ + L
Sbjct: 231 RERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKL 281
Score = 37.7 bits (86), Expect = 0.014
Identities = 26/111 (23%), Positives = 57/111 (51%), Gaps = 5/111 (4%)
Query: 116 EEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLRQ 175
E + RV +E E++E VL R ++ KL+ E + +EL++ ++ ++ + + R+
Sbjct: 232 ERQDRVFQEEEEKEWRKRETVL--RKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRE 289
Query: 176 HRLSEEER---RRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQ 223
+ E+++ RR+QQ +QE ++ +R E + ++E L+
Sbjct: 290 RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLR 340
Score = 37.7 bits (86), Expect = 0.014
Identities = 31/121 (25%), Positives = 54/121 (44%), Gaps = 6/121 (4%)
Query: 101 EHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDL 160
E R + +L +EE+R +++++EE + S+ + L L++
Sbjct: 734 EQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQ 793
Query: 161 NQRQAHVDFEAMLRQHRLSEEE---RRRQQQEEDEQETAALLEE---ARKRRLLEDSDSE 214
+RQ + Q L EEE +RR+Q+ E E+E L EE R+ R + + E
Sbjct: 794 RERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853
Query: 215 D 215
D
Sbjct: 854 D 854
Score = 37.7 bits (86), Expect = 0.014
Identities = 28/106 (26%), Positives = 53/106 (50%), Gaps = 8/106 (7%)
Query: 101 EHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDL 160
E R+ ++++ EEE+ +++ERE+++L + + R ++ +L++E E Q L+
Sbjct: 1784 EEQQLRSQESDRKFREEEQ-LRQEREEQQLRPQQRDGKYRWEEEQLQLE--EQEQRLRQE 1840
Query: 161 NQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRR 206
RQ + Q E+ RR +Q+ E+E E RK R
Sbjct: 1841 RDRQYRAE-----EQFATQEKSRREEQELWQEEEQKRRQERERKLR 1881
Score = 37.4 bits (85), Expect = 0.018
Identities = 23/109 (21%), Positives = 54/109 (49%)
Query: 106 RNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQA 165
R + +++ +EEE++ ++RE K+ E + + E E L++L+ R+
Sbjct: 230 RRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRE 289
Query: 166 HVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSE 214
+ E ++ R ++ RR+Q++E EQ+ ++ R+ + E + +
Sbjct: 290 RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQ 338
Score = 37.0 bits (84), Expect = 0.024
Identities = 28/111 (25%), Positives = 49/111 (44%), Gaps = 8/111 (7%)
Query: 106 RNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQA 165
R Q + EEE + Q+ER +++ E R + + + L QE + Q +
Sbjct: 302 REQQLRRKQEEERREQQEERREQQ--------ERREQQEERREQQLRREQEERREQQLRR 353
Query: 166 HVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDE 216
+ E +Q R +EE RR+QQ EQ+ + R+++L + E
Sbjct: 354 EQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRRE 404
Score = 37.0 bits (84), Expect = 0.024
Identities = 27/110 (24%), Positives = 56/110 (50%), Gaps = 5/110 (4%)
Query: 101 EHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDL 160
E G R ++ EEE+ +++ERE+++L+ + + R ++ K+ + E ++ +
Sbjct: 1544 ERGQQRRQDRDRKFREEEQ-LRQEREEQQLSRQERDRKFRLEEQKVRRQ--EQERKFMED 1600
Query: 161 NQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLED 210
Q+ + + LRQ R + + R +Q E+E L + R R+ LE+
Sbjct: 1601 EQQLRRQEGQQQLRQER--DRKFREDEQLLQEREEQQLHRQERDRKFLEE 1648
Score = 36.6 bits (83), Expect = 0.031
Identities = 26/115 (22%), Positives = 56/115 (48%), Gaps = 3/115 (2%)
Query: 101 EHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDL 160
E R Q + +EEE+R Q+ R +++L ++ + + ++ + L+ + L
Sbjct: 354 EQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 413
Query: 161 NQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSED 215
+R+ + E LR+ + EEER Q+ E++ +E E+ +R L+ + +
Sbjct: 414 -RREQQLRREQQLRREQ--EEERHEQKHEQERREQRLKREQEERRDWLKREEETE 465
Score = 36.6 bits (83), Expect = 0.031
Identities = 28/132 (21%), Positives = 60/132 (45%), Gaps = 23/132 (17%)
Query: 94 ENTDYTMEHGATRNFQAEKLL--EEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVL 151
+ + + H R F+ E+ L E EE++++++ D + + L + ++ K
Sbjct: 1655 QEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKF----- 1709
Query: 152 ENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDS 211
LQE + L +++ + + EEE+ RQ+ E+++ L + R R++LE+
Sbjct: 1710 --LQEEQQLRRQEL---------ERKFREEEQLRQETEQEQ-----LRRQERYRKILEEE 1753
Query: 212 DSEDEAAPSPLQ 223
E L+
Sbjct: 1754 QLRPEREEQQLR 1765
Score = 35.8 bits (81), Expect = 0.053
Identities = 35/121 (28%), Positives = 61/121 (50%), Gaps = 16/121 (13%)
Query: 109 QAEKLLEEEEKRVQKER---EDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQA 165
Q E+ L EE++ +++R E+EE + R K+ + +E E LQ + Q Q
Sbjct: 793 QRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQF-LEEEEQLQRRERAQQLQE 851
Query: 166 HVDFEAMLRQHRLSEEERRRQQ---QEEDEQE--------TAALLEEARK-RRLLEDSDS 213
D ++ R S+E+RR Q+ Q E+E++ AL E+ RK ++LL++ +
Sbjct: 852 EEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEE 911
Query: 214 E 214
E
Sbjct: 912 E 912
Score = 35.4 bits (80), Expect = 0.069
Identities = 29/116 (25%), Positives = 55/116 (47%), Gaps = 7/116 (6%)
Query: 106 RNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELK---DLNQ 162
R Q E+ ++E + Q+ER +++L + E R + + E E Q+L+ + +
Sbjct: 315 REQQEERREQQERREQQEERREQQLRREQE--ERREQQLRREQEEERREQQLRREQEEER 372
Query: 163 RQAHVDFEAMLR--QHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDE 216
R+ + E LR Q E++ RR+QQ EQ+ + R+++L + E
Sbjct: 373 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428
Score = 35.4 bits (80), Expect = 0.069
Identities = 36/142 (25%), Positives = 64/142 (45%), Gaps = 16/142 (11%)
Query: 110 AEKLLEEEEKRVQK--EREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHV 167
A+ L+E+ ++ Q+ + E+EEL E R K + E E +E + L Q + +
Sbjct: 891 AKPALQEQLRKEQQLLQEEEEELQR-----EEREKRRRQEQE--RQYREEEQLQQEEEQL 943
Query: 168 DFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQPALR 227
E ++ R E + R+ ++ ++E L EE KRR E E + L+
Sbjct: 944 LREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE------EEELQ 997
Query: 228 PNPTAILDEAPKPKRKVEVWEQ 249
+L E + KR+ + WE+
Sbjct: 998 QEEEQLLRE-EREKRRRQEWER 1018
Score = 35.4 bits (80), Expect = 0.069
Identities = 28/108 (25%), Positives = 55/108 (50%), Gaps = 3/108 (2%)
Query: 101 EHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDL 160
E +R + K EEE++ ++ERE + L ++ + R + + E ++L+ +E + L
Sbjct: 1420 EQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREE-QQL 1478
Query: 161 NQRQAHVDFEAMLRQHRLSEEERRRQQQE--EDEQETAALLEEARKRR 206
++++ F +Q R E +R+ ++QE E E L EE + R
Sbjct: 1479 HRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHR 1526
Score = 35.0 bits (79), Expect = 0.090
Identities = 20/58 (34%), Positives = 31/58 (53%)
Query: 157 LKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSE 214
L+D Q + FE RQ +RRRQ+++E E+E A E++ K+ LE D +
Sbjct: 110 LQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQ 167
Score = 35.0 bits (79), Expect = 0.090
Identities = 30/121 (24%), Positives = 56/121 (46%), Gaps = 6/121 (4%)
Query: 101 EHGATRNFQAEKLLEEEEKRVQKER---EDEELNNPMKVLENRTKDSKLEMEVLENLQEL 157
E R + E+ ++EE+R Q+ER ++E ++ + ++ +L E E +E
Sbjct: 303 EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERRE- 361
Query: 158 KDLNQRQAHVDFEAMLR--QHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSED 215
+ L + Q E LR Q E++ RR+QQ EQ+ + R+++L +
Sbjct: 362 QQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 421
Query: 216 E 216
E
Sbjct: 422 E 422
Score = 35.0 bits (79), Expect = 0.090
Identities = 42/156 (26%), Positives = 68/156 (43%), Gaps = 40/156 (25%)
Query: 101 EHGATRNFQAEKLLEEEEKRVQKERE---DEELNNPMK-----VLENRTKDSKLEMEVLE 152
E R + + EEEE + QK ++ DE+ + +K EN +D+K+ + E
Sbjct: 1187 EQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRE 1246
Query: 153 NLQ--ELKD--LNQRQAHVDFEAML--RQHRLSEEERRRQQQ------------------ 188
N Q +L+D L RQ+ D + +L +Q R E+ERRR QQ
Sbjct: 1247 NEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKE 1306
Query: 189 --------EEDEQETAALLEEARKRRLLEDSDSEDE 216
+E++Q EE R+R+ + E+E
Sbjct: 1307 AKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEE 1342
Score = 35.0 bits (79), Expect = 0.090
Identities = 28/114 (24%), Positives = 51/114 (44%), Gaps = 11/114 (9%)
Query: 106 RNFQAEKLL--EEEEKRVQKEREDEELNNPMKVLENRTKDSKL-EMEVLENLQELKDLNQ 162
R F+ E+ L E EE+++ ++ D + + L + +D K E E+ E K L +
Sbjct: 1461 RKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEE 1520
Query: 163 RQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDE 216
Q RQ + +EE++ ++QE +Q + R R+ E+ E
Sbjct: 1521 EQ---QLHRQQRQRKFLQEEQQLRRQERGQQR-----RQDRDRKFREEEQLRQE 1566
Score = 34.7 bits (78), Expect = 0.12
Identities = 33/135 (24%), Positives = 58/135 (42%), Gaps = 24/135 (17%)
Query: 89 FKTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEM 148
F+ + + E R + K LEEE++ ++ER+ K E + + E
Sbjct: 1463 FREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERD-------RKFREQELRSQEPER 1515
Query: 149 EVLENLQELKDLNQRQAHVDFEAMLRQ------------HRLSEEERRRQQQEE-----D 191
+ LE Q+L +++ + E LR+ + EEE+ RQ++EE
Sbjct: 1516 KFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQ 1575
Query: 192 EQETAALLEEARKRR 206
E++ LEE + RR
Sbjct: 1576 ERDRKFRLEEQKVRR 1590
Score = 34.7 bits (78), Expect = 0.12
Identities = 25/117 (21%), Positives = 51/117 (43%), Gaps = 4/117 (3%)
Query: 111 EKLLEE-EEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDF 169
E+LL+E EE+++ ++ D + L + ++ +L + +E + L Q
Sbjct: 1625 EQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQL 1684
Query: 170 EAMLRQHRLSEEERRRQQQEEDE---QETAALLEEARKRRLLEDSDSEDEAAPSPLQ 223
R + EEE++ ++QE + QE L + +R+ E+ E L+
Sbjct: 1685 RRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLR 1741
Score = 34.7 bits (78), Expect = 0.12
Identities = 23/127 (18%), Positives = 51/127 (40%), Gaps = 5/127 (3%)
Query: 101 EHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDL 160
E R + E+ +EE++++++ + + ++ + ++ E + E + L
Sbjct: 1696 EEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQL 1755
Query: 161 NQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPS 220
+ R + EEE+ RQ++EE + L + R+ E+ E
Sbjct: 1756 RPEREEQQLRRQERDRKFREEEQLRQEREEQQ-----LRSQESDRKFREEEQLRQEREEQ 1810
Query: 221 PLQPALR 227
L+P R
Sbjct: 1811 QLRPQQR 1817
Score = 33.9 bits (76), Expect = 0.20
Identities = 33/143 (23%), Positives = 64/143 (44%), Gaps = 4/143 (2%)
Query: 115 EEEEKRVQKEREDEELNNPMKVLENRT--KDSKLEMEVLENLQELK-DLNQRQAHVDFEA 171
E++ +R Q+ R +++L ++ + ++ +L E E E K + +R+ + E
Sbjct: 392 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQ 451
Query: 172 MLRQHRLS-EEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQPALRPNP 230
R+ L EEE R +QE +Q+ EE R+ R L+ + E + LR
Sbjct: 452 EERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQ 511
Query: 231 TAILDEAPKPKRKVEVWEQSVGS 253
++ K + + E +Q + S
Sbjct: 512 EERREQRLKRQEEEERLQQRLRS 534
Score = 33.9 bits (76), Expect = 0.20
Identities = 30/134 (22%), Positives = 59/134 (44%), Gaps = 15/134 (11%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD 168
+ E+L +EEE+ +++ERE + + + + E ++L +E + L +R+
Sbjct: 992 EEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYR 1051
Query: 169 FEAMLRQHR---LSEEERRRQQQ------------EEDEQETAALLEEARKRRLLEDSDS 213
E L+Q L EE R++Q +++E++ E R+R+ E
Sbjct: 1052 EEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCR 1111
Query: 214 EDEAAPSPLQPALR 227
E+E + LR
Sbjct: 1112 EEEELQQEEEQLLR 1125
Score = 33.5 bits (75), Expect = 0.26
Identities = 25/101 (24%), Positives = 50/101 (49%), Gaps = 9/101 (8%)
Query: 115 EEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLR 174
+EEE++ Q+ R +++L + E R + + E E ++ ++ ++Q + E
Sbjct: 291 QEEEQQQQRLRREQQLRRKQE--EERREQQEERREQQERREQQEERREQQLRREQEERRE 348
Query: 175 QH--RLSEEERR-----RQQQEEDEQETAALLEEARKRRLL 208
Q R EEERR R+Q+EE ++ ++ R+ + L
Sbjct: 349 QQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389
Score = 33.5 bits (75), Expect = 0.26
Identities = 28/115 (24%), Positives = 53/115 (46%), Gaps = 12/115 (10%)
Query: 106 RNFQAEKLLEEEEKRVQ--------KEREDEELNNPM--KVLENRTKDSKLEMEVLENLQ 155
R F+ E+ L +E + Q K RE+E+L + L + +D K E E
Sbjct: 1771 RKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWE--EEQL 1828
Query: 156 ELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLED 210
+L++ QR + + + +E+ R++++E QE + R+R+L E+
Sbjct: 1829 QLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREE 1883
Score = 33.1 bits (74), Expect = 0.34
Identities = 27/108 (25%), Positives = 45/108 (41%), Gaps = 12/108 (11%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD 168
Q K LEEE++ ++ERE + L ++ E Q+L+ R+ +
Sbjct: 1372 QGRKFLEEEQRLRRQERERKFLKEEQ------------QLRCQEREQQLRQDRDRKFREE 1419
Query: 169 FEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDE 216
+ + RQ R + QQ E+E L EE + R+ E+E
Sbjct: 1420 EQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEE 1467
Score = 32.0 bits (71), Expect = 0.76
Identities = 24/102 (23%), Positives = 47/102 (46%), Gaps = 13/102 (12%)
Query: 115 EEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLR 174
E EE+R ++E +EE + +++R + ++E + + RQ+ V
Sbjct: 675 EHEEERREQELAEEEQEQARERIKSRIPKWQWQLE--------SEADARQSKV-----YS 721
Query: 175 QHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDE 216
+ R E +RRRQ+QEE + + L+ + R E++
Sbjct: 722 RPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQ 763
Score = 32.0 bits (71), Expect = 0.76
Identities = 27/112 (24%), Positives = 55/112 (49%), Gaps = 18/112 (16%)
Query: 117 EEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDF------- 169
EE+++ +ERE++ L + + R ++ + + + + L+E + L +++ F
Sbjct: 1340 EEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQL 1399
Query: 170 -----EAMLRQHR---LSEEERRRQQQEED---EQETAALLEEARKRRLLED 210
E LRQ R EEE++ +QE D +E + + R+R+ LE+
Sbjct: 1400 RCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEE 1451
Score = 32.0 bits (71), Expect = 0.76
Identities = 22/107 (20%), Positives = 45/107 (42%), Gaps = 5/107 (4%)
Query: 117 EEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLRQH 176
EE++V+++ ++ + + L + +L E +E + L Q + R
Sbjct: 1584 EEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDR 1643
Query: 177 RLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQ 223
+ EEE + ++QE ++Q L R R+ E+ E L+
Sbjct: 1644 KFLEEEPQLRRQEREQQ-----LRHDRDRKFREEEQLLQEGEEQQLR 1685
Score = 31.6 bits (70), Expect = 1.00
Identities = 31/109 (28%), Positives = 51/109 (46%), Gaps = 6/109 (5%)
Query: 111 EKLLEE-EEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQ--RQAHV 167
++L E EE+R Q+ R ++E + L ++ + E + L Q+L+ Q R+ +
Sbjct: 337 QQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQ-LRREQQLRREQQLRREQQL 395
Query: 168 DFEAMLR--QHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSE 214
E LR Q E++ RR+QQ EQ+ EE R + E E
Sbjct: 396 RREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERRE 444
Score = 31.2 bits (69), Expect = 1.3
Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 9/88 (10%)
Query: 162 QRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSP 221
+++A D + L Q R EE++RR + + + E EE +RR + + E E A
Sbjct: 98 EKRARCDGKESLLQDRRQEEDQRRFEPRDRQLE-----EEPGQRRRQKRQEQERELAEGE 152
Query: 222 LQPALRPNPTAILDEAPKPKRKVEVWEQ 249
Q + L++ + +R E+W Q
Sbjct: 153 EQSEKQER----LEQRDRQRRDEELWRQ 176
Score = 29.3 bits (64), Expect = 4.9
Identities = 25/108 (23%), Positives = 49/108 (45%), Gaps = 11/108 (10%)
Query: 105 TRNFQAEKLLEEEEKRVQKERE-DEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQR 163
T +QAE+ E +R+ E+ ++ E + ++ + E E Q + +R
Sbjct: 768 TWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRER 827
Query: 164 QAHVDFEAMLRQHRLSEEER--RRQQQEEDEQETAALLEEARKRRLLE 209
+ + F L EEE+ RR++ ++ ++E L E+ +RR E
Sbjct: 828 EKELQF--------LEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQE 867
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 47.4 bits (111), Expect = 2e-05
Identities = 30/150 (20%), Positives = 74/150 (49%), Gaps = 9/150 (6%)
Query: 109 QAEKLLEEEEKRVQKE--------REDEELNNPMKVLENRTKDSKLEMEVLENLQELKDL 160
+ EK+ EEE+++ Q+E RE EE+ + + + K K E +V +++ D
Sbjct: 448 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQ 507
Query: 161 NQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPS 220
++ + + ++ ++ E+E + ++QEE +E +++E ++ ++ +++
Sbjct: 508 EEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMR 567
Query: 221 PLQPALRPNPTAILDEAPKPKRKVE-VWEQ 249
+ +R I ++ K + + E +WEQ
Sbjct: 568 RQEEKIREQEEKIREQKEKIREQEEKIWEQ 597
Score = 45.8 bits (107), Expect = 5e-05
Identities = 38/146 (26%), Positives = 68/146 (46%), Gaps = 7/146 (4%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD 168
Q EK+ E+EEK ++E + E ++ E + + E E + QE K Q + +
Sbjct: 507 QEEKIREQEEKMWRQEEKIREQEEKIREQEEKIR----EQEEMMQEQEEKMGEQEEKMQE 562
Query: 169 FEAMLRQHRL--SEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQPAL 226
E M RQ +EE+ R+Q+E+ ++ + E+ K R E+ E E + +
Sbjct: 563 QEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKM 622
Query: 227 RPNPTAILDEAPKPKRKVE-VWEQSV 251
+ ++ K +R+ E +WEQ V
Sbjct: 623 CEQEEKMQEQEEKMRRQEEKMWEQEV 648
Score = 42.4 bits (98), Expect = 6e-04
Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 9/127 (7%)
Query: 94 ENTDYTMEHGATRNFQAEKLLEEEEKRVQKE--REDEELNNPMKVLENRTKDSKLEMEVL 151
E + E Q EK+ E+E+ R Q+E RE EE K+ E + K + E ++
Sbjct: 541 EQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEE-----KIREQKEKIREQEEKIW 595
Query: 152 ENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEED--EQETAALLEEARKRRLLE 209
E +++++ + + + ++ ++ E+E + Q+QEE QE +E R R+ E
Sbjct: 596 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 655
Query: 210 DSDSEDE 216
E
Sbjct: 656 KMQEHQE 662
Score = 41.6 bits (96), Expect = 0.001
Identities = 33/145 (22%), Positives = 66/145 (45%), Gaps = 7/145 (4%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD 168
Q EK+ E+EEK ++E E M+ E + + +M LE + K+ R+
Sbjct: 326 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELE-- 383
Query: 169 FEAMLRQHRLSEEERRRQQQEEDEQETAALLEEAR----KRRLLEDSDSEDEAAPSPLQP 224
E M Q ++ E+E +RQ++E+ ++ +EA+ + ++ E + E +
Sbjct: 384 -EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ 442
Query: 225 ALRPNPTAILDEAPKPKRKVEVWEQ 249
+ + + E K + + E+W Q
Sbjct: 443 EEKIHEQEKIREEEKRQEQEEMWRQ 467
Score = 40.4 bits (93), Expect = 0.002
Identities = 24/86 (27%), Positives = 49/86 (56%), Gaps = 5/86 (5%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD 168
+ EK+ E+EEKR +E+E++ K E K + E ++ E +++++ ++ +
Sbjct: 388 EQEKIREQEEKR----QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE 443
Query: 169 FEAMLRQHRLSEEERRRQQQEEDEQE 194
E + Q ++ EEE+R++Q+E QE
Sbjct: 444 -EKIHEQEKIREEEKRQEQEEMWRQE 468
Score = 38.9 bits (89), Expect = 0.006
Identities = 31/99 (31%), Positives = 51/99 (51%), Gaps = 5/99 (5%)
Query: 109 QAEKLLEEEEK-RVQKE--REDEEL--NNPMKVLENRTKDSKLEMEVLENLQELKDLNQR 163
Q EK+ E+EEK R QKE RE EE K+ E + E ++ E +++ + ++
Sbjct: 569 QEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 628
Query: 164 QAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEA 202
+ + ++ ++ E+E R +QQEE QE LE A
Sbjct: 629 MQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 667
Score = 35.8 bits (81), Expect = 0.053
Identities = 34/147 (23%), Positives = 66/147 (44%), Gaps = 10/147 (6%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQ-ELKDLNQRQAHV 167
Q EK+ +EEK + E + +E ++ E + ++ + +M E + E ++ +RQ +
Sbjct: 298 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEM 357
Query: 168 DFEAMLRQHRLS----EEERRRQQQEEDEQETAALLEEARKRRLLE-----DSDSEDEAA 218
+E + RL E+E + ++ EE E + E+ KR+ E + E EA
Sbjct: 358 MWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 417
Query: 219 PSPLQPALRPNPTAILDEAPKPKRKVE 245
+ +R I ++ K R+ E
Sbjct: 418 MWRQEEKIREQEEKIREQEKKMWRQEE 444
Score = 34.3 bits (77), Expect = 0.15
Identities = 33/153 (21%), Positives = 70/153 (45%), Gaps = 21/153 (13%)
Query: 109 QAEKLLEEEEKRVQKE----REDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQ 164
Q EK+ E+EEK ++E R++E+++ K+ E + + EM QE K Q
Sbjct: 421 QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMW----RQEEKIREQE- 475
Query: 165 AHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQP 224
E ++ ++ E+E+ R+Q+E+ ++ + ++ K R E E +
Sbjct: 476 -----EIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIR-------EQEEKMWRQEE 523
Query: 225 ALRPNPTAILDEAPKPKRKVEVWEQSVGSLGSR 257
+R I ++ K + + E+ ++ +G +
Sbjct: 524 KIREQEEKIREQEEKIREQEEMMQEQEEKMGEQ 556
Score = 30.4 bits (67), Expect = 2.2
Identities = 39/185 (21%), Positives = 84/185 (45%), Gaps = 27/185 (14%)
Query: 79 KCTRCLAEITFKTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQK-----EREDEELNNP 133
K R + E+T + D + + RN ++ L+E+ ++Q+ E E E+
Sbjct: 190 KADRYIEELTKERDALSLELY------RNTITDEELKEKNAKLQEKLQLVESEKSEIQLN 243
Query: 134 MKVLENRTKDSKL-------EMEVLENLQELKDLNQR-QAHVDFEAMLRQHRLSEEERRR 185
+K L+ + + +KL + E +EL+ ++ + QA V+ + + +EE+
Sbjct: 244 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 303
Query: 186 QQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQPALRPNPTAILDEAPKPKRKVE 245
+Q+E+ ++ + E+ K R E+ E E +R + ++ K +R+ E
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQE-------EKMRRQEEMMWEKEEKMRRQEE 356
Query: 246 -VWEQ 249
+WE+
Sbjct: 357 MMWEK 361
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 46.2 bits (108), Expect = 4e-05
Identities = 34/152 (22%), Positives = 72/152 (47%), Gaps = 11/152 (7%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD 168
Q EK+ E+EEKR +E+E++ K+ E K + E ++ E +++++ + +
Sbjct: 589 QEEKIREQEEKR--QEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQE 646
Query: 169 FEAMLRQHRLSEEERRRQQQEED--------EQETAALLEEARKRRLLEDSDSEDEAAPS 220
+ ++ ++ E+E + Q+QEE ++ + E+ K R E+ E E
Sbjct: 647 EKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 706
Query: 221 PLQPALRPNPTAILDEAPKPKRKVE-VWEQSV 251
+ + + ++ K +R+ E +WEQ V
Sbjct: 707 EQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738
Score = 41.2 bits (95), Expect = 0.001
Identities = 33/153 (21%), Positives = 70/153 (45%), Gaps = 17/153 (11%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD 168
+ EK+ E+EEKR +E+E++ K E K + E ++ E +++++ ++ +
Sbjct: 402 EQEKIREQEEKR----QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE 457
Query: 169 FEAMLRQHRLSEEERRRQQ------------QEEDEQETAALLEEARKRRLLEDSDSEDE 216
E + Q ++ EEE+R++Q QEE ++ + E+ K R E+ E
Sbjct: 458 -EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQE 516
Query: 217 AAPSPLQPALRPNPTAILDEAPKPKRKVEVWEQ 249
+ +R + + K + + E+W +
Sbjct: 517 EKIREQEEKIREQEEKMWRQEEKIREQEEMWRE 549
Score = 40.0 bits (92), Expect = 0.003
Identities = 24/112 (21%), Positives = 53/112 (47%), Gaps = 2/112 (1%)
Query: 94 ENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLEN 153
E + T E Q EK+ E+EEK +E+E+ K+ E K + E ++ E
Sbjct: 637 EQEEMTQEQEEKMGEQEEKMCEQEEK--MQEQEETMWRQEEKIREQEKKIREQEEKIREQ 694
Query: 154 LQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKR 205
+ +++ ++ + + ++ ++ E+E + ++QEE E L + ++
Sbjct: 695 EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 746
Score = 39.7 bits (91), Expect = 0.004
Identities = 31/142 (21%), Positives = 68/142 (47%), Gaps = 5/142 (3%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQ-ELKDLNQRQAHV 167
Q EK+ +EEK + E + +E ++ E + ++ + +M E + E ++ +RQ +
Sbjct: 298 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEM 357
Query: 168 DFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQPALR 227
+E + R +EE +++E+ ++ + E+ K R LE+ E E Q R
Sbjct: 358 MWEKEEKMRR--QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE--QEEKR 413
Query: 228 PNPTAILDEAPKPKRKVEVWEQ 249
I ++ + +++ ++W Q
Sbjct: 414 QEEEKIREQEKRQEQEAKMWRQ 435
Score = 38.1 bits (87), Expect = 0.011
Identities = 34/152 (22%), Positives = 65/152 (42%), Gaps = 11/152 (7%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD 168
Q EK+ E+EEK ++E + E + E + K+ E QE K Q + +
Sbjct: 522 QEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIRE 581
Query: 169 FEAML--RQHRLSEEERRRQQQEED--------EQETAALLEEARKRRLLEDSDSEDEAA 218
E + ++ ++ E+E +RQ+QEE ++ + E+ K R E+ E E
Sbjct: 582 QEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEM 641
Query: 219 PSPLQPALRPNPTAILDEAPKPKRKVE-VWEQ 249
+ + + ++ K + + E +W Q
Sbjct: 642 TQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQ 673
Score = 37.4 bits (85), Expect = 0.018
Identities = 31/146 (21%), Positives = 72/146 (49%), Gaps = 9/146 (6%)
Query: 109 QAEKLLEEEEKRVQKER----EDEELNNPMKVLENRTKDSKLEMEVL-ENLQELKDLNQR 163
Q E + E+EEK ++E ++E++ +++ + + + + E++ E +++++L ++
Sbjct: 340 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 399
Query: 164 QAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQ 223
H + ++ + EEE+ R+Q++ EQE A + + K R E+ E E +
Sbjct: 400 M-HEQEKIREQEEKRQEEEKIREQEKRQEQE-AKMWRQEEKIREQEEKIREQEKKMWRQE 457
Query: 224 PALRPNPTAILDEAPKPKRKVEVWEQ 249
+ + E K + + E+W Q
Sbjct: 458 EKIHEQEK--IREEEKRQEQEEMWRQ 481
Score = 36.6 bits (83), Expect = 0.031
Identities = 35/163 (21%), Positives = 73/163 (44%), Gaps = 18/163 (11%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD 168
Q EK+ E+EEK +++E++ K+ E K + E ++ QE K Q + +
Sbjct: 494 QKEKMHEQEEKI--RKQEEKVWRQEEKIREQEEKIREQEEKMWR--QEEKIREQEEMWRE 549
Query: 169 FEAMLRQHRLSEEERR--------------RQQQEEDEQETAALLEEARKRRLLEDSDSE 214
E M Q ++ EEE+R R+Q+E+ ++ + E+ KR+ E+ +
Sbjct: 550 EEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWK 609
Query: 215 DEAAPSPLQPALRPNPTAILDEAPKPKRKVEVWEQSVGSLGSR 257
E + ++ I ++ K + + E+ ++ +G +
Sbjct: 610 QEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQ 652
Score = 36.6 bits (83), Expect = 0.031
Identities = 34/156 (21%), Positives = 74/156 (47%), Gaps = 9/156 (5%)
Query: 102 HGATRNFQAEKLLEEEEK---RVQKEREDEE--LNNPMKVLENRTKDSKLEMEVLENLQE 156
H + ++ EK E+E+K + +K RE EE K+ E K + E ++ + ++
Sbjct: 554 HEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEK 613
Query: 157 LKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEE--DEQETAALLEEARKRRLLEDSDSE 214
+++ ++ + + ++ ++ E+E Q+QEE EQE + E+ K + E++
Sbjct: 614 IREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQE-EKMCEQEEKMQEQEETMWR 672
Query: 215 DEAAPSPLQPALRPNPTAILD-EAPKPKRKVEVWEQ 249
E + +R I + E +++ ++WEQ
Sbjct: 673 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ 708
Score = 34.3 bits (77), Expect = 0.15
Identities = 35/151 (23%), Positives = 72/151 (47%), Gaps = 12/151 (7%)
Query: 109 QAEKLLEEEEKRVQKE--REDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAH 166
+ EK+ EEE+++ Q+E R++E+++ ++ R K+ E E QE K Q +
Sbjct: 462 EQEKIREEEKRQEQEEMWRQEEKIHEQEEIW--RQKEKMHEQEEKIRKQEEKVWRQEEKI 519
Query: 167 VDFEAMLRQH--RLSEEERRRQQQEEDEQETAALLE-----EARKRRLLEDSD-SEDEAA 218
+ E +R+ ++ +E + ++QEE +E + E E KR+ ED ++E
Sbjct: 520 REQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKI 579
Query: 219 PSPLQPALRPNPTAILDEAPKPKRKVEVWEQ 249
+ R E + +++ ++W+Q
Sbjct: 580 REQEEKVWRQEEKIREQEEKRQEQEEKMWKQ 610
Score = 33.1 bits (74), Expect = 0.34
Identities = 24/123 (19%), Positives = 56/123 (45%), Gaps = 15/123 (12%)
Query: 109 QAEKLLEEEEKRVQKE----REDEELNNPMKVLENRTKDSKLEM-----------EVLEN 153
Q EK+ E+EEK ++E R++E+++ K+ E + + EM E+
Sbjct: 435 QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQ 494
Query: 154 LQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDS 213
+++ + ++ + + ++ ++ E+E + ++QEE + E + E+
Sbjct: 495 KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMH 554
Query: 214 EDE 216
E E
Sbjct: 555 EQE 557
Score = 30.4 bits (67), Expect = 2.2
Identities = 39/185 (21%), Positives = 84/185 (45%), Gaps = 27/185 (14%)
Query: 79 KCTRCLAEITFKTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQK-----EREDEELNNP 133
K R + E+T + D + + RN ++ L+E+ ++Q+ E E E+
Sbjct: 190 KADRYIEELTKERDALSLELY------RNTITDEELKEKNAKLQEKLQLVESEKSEIQLN 243
Query: 134 MKVLENRTKDSKL-------EMEVLENLQELKDLNQR-QAHVDFEAMLRQHRLSEEERRR 185
+K L+ + + +KL + E +EL+ ++ + QA V+ + + +EE+
Sbjct: 244 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 303
Query: 186 QQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQPALRPNPTAILDEAPKPKRKVE 245
+Q+E+ ++ + E+ K R E+ E E +R + ++ K +R+ E
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQE-------EKMRRQEEMMWEKEEKMRRQEE 356
Query: 246 -VWEQ 249
+WE+
Sbjct: 357 MMWEK 361
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 46.2 bits (108), Expect = 4e-05
Identities = 49/172 (28%), Positives = 77/172 (44%), Gaps = 28/172 (16%)
Query: 92 DPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENR----TKDSKLE 147
D E + A RN + E EEEE+ ++E +DEE + ++R K+ K E
Sbjct: 251 DQETPSRNLRVRADRNLKTE---EEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEE 307
Query: 148 MEVLENL--QELKDLNQRQAHVDFEAMLRQHRL--SEEERRR----QQQEEDEQETAALL 199
E + + +E+ D + + E + R R S+EE R+ +QQ+E E +T + L
Sbjct: 308 GEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPL 367
Query: 200 EEARKRRLLEDSDSEDEAAPSPLQPALR-----------PNPTAILDEAPKP 240
EE + R ++ S E + SP P L P TA +E P P
Sbjct: 368 EE--EEREIKSSQGLKEKSKSPSPPRLTEDRKKASLVALPEQTASEEETPPP 417
Score = 37.0 bits (84), Expect = 0.024
Identities = 28/99 (28%), Positives = 48/99 (48%), Gaps = 9/99 (9%)
Query: 111 EKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFE 170
E+ +E+K +KE+ EE P K+L++ + +K + + Q++A
Sbjct: 1187 ERAKSKEKKSEKKEKAQEE--PPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAE---- 1240
Query: 171 AMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLE 209
R R E E+RR++QEE+EQ+ E + R LE
Sbjct: 1241 ---RAERAKEREKRRKEQEEEEQKEREKEAERERNRQLE 1276
Score = 32.3 bits (72), Expect = 0.58
Identities = 35/157 (22%), Positives = 62/157 (39%), Gaps = 22/157 (14%)
Query: 155 QELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSE 214
+E ++ R V + L+ EEE ++ +E E+E +++R+ +L++ E
Sbjct: 249 EEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDE-EEEGDDEGQKSREAPILKEFKEE 307
Query: 215 DEAAPSPLQPALRPNPTAILDEAPKPKRKVEVWEQSVGSLGSR----------PPLSRLV 264
E P R P ++DE PK + + EQ V G R L+R
Sbjct: 308 GEEIP-------RVKPEEMMDERPKTRSQ----EQEVLERGGRFTRSQEEARKSHLARQQ 356
Query: 265 VVKKAKADPDCSNGQPQAAPTPGAPQNRKEANPTPLT 301
K+ K + + + G + K +P LT
Sbjct: 357 QEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLT 393
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 45.8 bits (107), Expect = 5e-05
Identities = 34/150 (22%), Positives = 69/150 (46%), Gaps = 7/150 (4%)
Query: 106 RNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQA 165
+ + +K L E+E+++Q E+E++ K+ E K + E + E +++++ Q+
Sbjct: 297 KELREQKKLREQEEQMQ-EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 355
Query: 166 HVDFEAMLRQHRLSEEERRRQ------QQEEDEQETAALLEEARKRRLLEDSDSEDEAAP 219
+ + RL E+E R + +QEE QE + E +K R E++ E E
Sbjct: 356 DQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKM 415
Query: 220 SPLQPALRPNPTAILDEAPKPKRKVEVWEQ 249
+ + + P++K ++WEQ
Sbjct: 416 QKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 445
Score = 43.5 bits (101), Expect = 3e-04
Identities = 37/181 (20%), Positives = 76/181 (41%), Gaps = 5/181 (2%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD 168
Q EK+ E+EEK ++E ED+ + E K + E ++ E +++++ ++ +
Sbjct: 607 QEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE 666
Query: 169 FEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQPALRP 228
+ ++ ++ E+E + Q QEE +E + ++ ++ + Q +R
Sbjct: 667 EKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMRE 726
Query: 229 NPTAILDEAPKPKRKVEVWEQSVGSLGSRPPLSRLVVVKKA----KADPDCSNGQPQAAP 284
I D+ K + ++ E+ S PP L + A + G PQ P
Sbjct: 727 KEERIRDQKEKMQERLPEHEERC-SEPCLPPSKVLCNMSHTGSVEPAGGEAGEGSPQDNP 785
Query: 285 T 285
T
Sbjct: 786 T 786
Score = 42.7 bits (99), Expect = 4e-04
Identities = 35/145 (24%), Positives = 69/145 (47%), Gaps = 9/145 (6%)
Query: 108 FQAEKLLEEEEKRVQKEREDEELNNPMKVLENRT--KDSKLEMEVLENLQELKDLNQRQA 165
++ EK+ E+E++ ++E + + M E R +D +L E E ++E K + Q++
Sbjct: 476 WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLR-EKEERMREQKKMWQQE- 533
Query: 166 HVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQPA 225
E M + + E+E++ QEE +E + E +K R E+ E E +
Sbjct: 534 ----EKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEK 589
Query: 226 LRPNPTAILDEAPKPKRKVE-VWEQ 249
+R + ++ K + + E +WEQ
Sbjct: 590 MREQEEKMWEQEEKMQEQEEKMWEQ 614
Score = 41.2 bits (95), Expect = 0.001
Identities = 31/113 (27%), Positives = 55/113 (48%), Gaps = 9/113 (7%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPM-----KVLENRTKDSKLEMEVLENLQELKDLNQR 163
Q EK+ E+EEK ++E + +E M K+ E +D E E + QE K Q
Sbjct: 586 QEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQE 645
Query: 164 QAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDE 216
+ + E +R+ +EE+ R+Q+E+ + + + E+ K + E+ E E
Sbjct: 646 EKMWEQEEKMRE----QEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQE 694
Score = 40.0 bits (92), Expect = 0.003
Identities = 35/158 (22%), Positives = 72/158 (45%), Gaps = 16/158 (10%)
Query: 108 FQAEKLLEEEEK---RVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQ 164
++ EK+ E+EEK + +K R+ EE+ K + + K + E ++ E ++++D Q+
Sbjct: 443 WEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM 502
Query: 165 AHVDFEAMLRQHRLSE-EERRRQQ----QEEDEQETAALLEEARKRRLLEDSDSEDEAAP 219
+ + RL E EER R+Q Q+E++ +E K+ ++ +E
Sbjct: 503 WDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERM 562
Query: 220 SPLQPALRPNPTAILDEAPKPKRKVE--------VWEQ 249
+ +R + ++ K + + E +WEQ
Sbjct: 563 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ 600
Score = 39.3 bits (90), Expect = 0.005
Identities = 34/144 (23%), Positives = 65/144 (45%), Gaps = 7/144 (4%)
Query: 109 QAEKLLEEE--EKRVQKEREDEEL----NNPMKVLENRTKDSKLEM-EVLENLQELKDLN 161
Q EK+ EEE +R +K RE+EE+ M+ E + ++ + +M E E +QE ++
Sbjct: 552 QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKM 611
Query: 162 QRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSP 221
Q +E +EE +Q+E+ +++ + E+ K R E+ E E
Sbjct: 612 WEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQG 671
Query: 222 LQPALRPNPTAILDEAPKPKRKVE 245
+ +R + + K + + E
Sbjct: 672 QEEKMREQEEKMQGQEEKMREQEE 695
Score = 38.5 bits (88), Expect = 0.008
Identities = 31/146 (21%), Positives = 67/146 (45%), Gaps = 9/146 (6%)
Query: 111 EKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFE 170
EK L E+EK ++++ ++EL K+ E + + E ++ E +++++ ++ +
Sbjct: 282 EKRLREQEKELREQ--EKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER 339
Query: 171 AMLRQHRLSEEERRRQQQEE-----DE--QETAALLEEARKRRLLEDSDSEDEAAPSPLQ 223
++ ++ E+E++ + QEE DE +E + E K E+ E+E +
Sbjct: 340 LWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREK 399
Query: 224 PALRPNPTAILDEAPKPKRKVEVWEQ 249
T E K++ +WEQ
Sbjct: 400 KMREEEETMREQEEKMQKQEENMWEQ 425
Score = 37.0 bits (84), Expect = 0.024
Identities = 27/111 (24%), Positives = 53/111 (47%), Gaps = 4/111 (3%)
Query: 97 DYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLEN--- 153
D + R + EK+ E+EEK +Q+E E M+ E ++ + +M+ E
Sbjct: 365 DERLREKEERMREQEKMWEQEEK-MQEEERIREREKKMREEEETMREQEEKMQKQEENMW 423
Query: 154 LQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARK 204
QE K+ Q++ E + Q ++ E+E + +QEE ++ + + +K
Sbjct: 424 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKK 474
Score = 36.6 bits (83), Expect = 0.031
Identities = 29/141 (20%), Positives = 63/141 (44%), Gaps = 16/141 (11%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD 168
Q E+L E+E K ++E + ++ E ++ + E+ + L+E ++ Q Q
Sbjct: 260 QEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKM 319
Query: 169 FEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQPALRP 228
+E +EE+ R+Q+E+ ++ L E+ ++ R E + E LR
Sbjct: 320 WE---------QEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLR- 369
Query: 229 NPTAILDEAPKPKRKVEVWEQ 249
++ + + + ++WEQ
Sbjct: 370 ------EKEERMREQEKMWEQ 384
Score = 34.3 bits (77), Expect = 0.15
Identities = 28/112 (25%), Positives = 55/112 (49%), Gaps = 6/112 (5%)
Query: 108 FQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHV 167
+Q E+ + EE+K ++E++ + M+ E + K E E ++E ++ Q Q
Sbjct: 530 WQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEK 589
Query: 168 DFEAMLRQHRLSEEERRRQQQEE---DEQETAALLEEARKRRLLEDSDSEDE 216
E ++ ++ E+E + Q+QEE +++E EE K + E+ E E
Sbjct: 590 MRE---QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQE 638
Score = 33.5 bits (75), Expect = 0.26
Identities = 37/172 (21%), Positives = 73/172 (42%), Gaps = 6/172 (3%)
Query: 79 KCTRCLAEITFKTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLE 138
K R + E+T + D + + + T +K E +EK E E E+ +K L+
Sbjct: 156 KADRYIEELTKERDALSLEL-YRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELK 214
Query: 139 NRTKDSKLEM-EVLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAA 197
+ + +K + +V N + + Q + + E +R+ +EE+ +Q+E ++
Sbjct: 215 RKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRK----QEEKMWRQEERLREQEGK 270
Query: 198 LLEEARKRRLLEDSDSEDEAAPSPLQPALRPNPTAILDEAPKPKRKVEVWEQ 249
+ E+ K R E E E + LR E +++ ++WEQ
Sbjct: 271 MREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQ 322
Score = 33.1 bits (74), Expect = 0.34
Identities = 26/143 (18%), Positives = 66/143 (46%), Gaps = 8/143 (5%)
Query: 111 EKLLEEEEKRV----QKEREDEEL-NNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQA 165
EK +E+EK+ +K RE+E + K+ E + E ++ E +++++ ++
Sbjct: 539 EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMW 598
Query: 166 HVDFEAMLRQHRLSEEERRRQQQEED---EQETAALLEEARKRRLLEDSDSEDEAAPSPL 222
+ + ++ ++ E+E + +QEE+ +++ + E+ K + E+ E E
Sbjct: 599 EQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ 658
Query: 223 QPALRPNPTAILDEAPKPKRKVE 245
+ +R + + K + + E
Sbjct: 659 EEKMREQEEKMQGQEEKMREQEE 681
Score = 32.0 bits (71), Expect = 0.76
Identities = 32/170 (18%), Positives = 68/170 (40%), Gaps = 14/170 (8%)
Query: 94 ENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKL------- 146
E + E R + + EEE R Q+E+ ++ N + E + +L
Sbjct: 383 EQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL 442
Query: 147 -EMEVLENL------QELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALL 199
E E ++ QE K +Q + + M RQ ++ E+E + +QEE ++ +
Sbjct: 443 WEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM 502
Query: 200 EEARKRRLLEDSDSEDEAAPSPLQPALRPNPTAILDEAPKPKRKVEVWEQ 249
+ +R +D ++ Q + + +E +++ + W+Q
Sbjct: 503 WDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQ 552
Score = 32.0 bits (71), Expect = 0.76
Identities = 29/136 (21%), Positives = 53/136 (38%), Gaps = 3/136 (2%)
Query: 92 DPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVL 151
+ E D E Q EK+ E+EEK ++E + E M+ E + + + +M
Sbjct: 620 EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQ 679
Query: 152 ENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEA---RKRRLL 208
E + ++ R+ + EE+ Q+++ QE EE +K ++
Sbjct: 680 EEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQ 739
Query: 209 EDSDSEDEAAPSPLQP 224
E +E P P
Sbjct: 740 ERLPEHEERCSEPCLP 755
Score = 31.2 bits (69), Expect = 1.3
Identities = 25/111 (22%), Positives = 53/111 (47%), Gaps = 9/111 (8%)
Query: 109 QAEKLLEEEEKRVQKE---REDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQA 165
+A+ LL + + +E R++EEL E K K E ++ + L++ +
Sbjct: 219 RAKFLLPQVQTNTLQEEMWRQEEELR------EQEKKIRKQEEKMWRQEERLREQEGKMR 272
Query: 166 HVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDE 216
+ + ++ RL E+E+ ++QE++ +E L E+ + + E+ E E
Sbjct: 273 EQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQE 323
Score = 30.0 bits (66), Expect = 2.9
Identities = 24/118 (20%), Positives = 54/118 (45%), Gaps = 10/118 (8%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHV- 167
Q +++ E+E+K +E E + ++ E R ++ + E E +QE + + +R+ +
Sbjct: 343 QEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMR 402
Query: 168 -DFEAMLRQHR--------LSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDE 216
+ E M Q + E+E + QQ+ ++ L E+ + + E ++E
Sbjct: 403 EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 460
>gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens]
Length = 250
Score = 45.8 bits (107), Expect = 5e-05
Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 6/112 (5%)
Query: 111 EKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD-- 168
E+ EEEE + ++E ++EE P + K++ + ++ ++ KDL + QA +D
Sbjct: 11 EQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSH 70
Query: 169 FEAMLRQHR----LSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDE 216
FEA ++ L E +R+ + ++Q A E R+ RL E+ +E
Sbjct: 71 FEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREE 122
>gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens]
Length = 250
Score = 45.8 bits (107), Expect = 5e-05
Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 6/112 (5%)
Query: 111 EKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD-- 168
E+ EEEE + ++E ++EE P + K++ + ++ ++ KDL + QA +D
Sbjct: 11 EQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSH 70
Query: 169 FEAMLRQHR----LSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDE 216
FEA ++ L E +R+ + ++Q A E R+ RL E+ +E
Sbjct: 71 FEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREE 122
>gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens]
Length = 841
Score = 45.4 bits (106), Expect = 7e-05
Identities = 39/142 (27%), Positives = 68/142 (47%), Gaps = 19/142 (13%)
Query: 84 LAEITFKTDPENTDYTMEHGATRNFQAEKLL--------EEEEKRVQKEREDEELNNPMK 135
L E+ +T E + + E GA R +++L E E K+R++EEL ++
Sbjct: 433 LDELAMETLQEKSQHKEELGAVRLRHEKEVLGVRARYERELRELHEDKKRQEEELRGQIR 492
Query: 136 VLENRTKDSKLEMEVLENLQELKDLNQRQAH-VDFEAMLRQHRLSEEERRRQQQEEDEQE 194
+ RT++ LE LQ+ + Q Q H +D + RL E E QQQ+++++E
Sbjct: 493 EEKARTRE-------LETLQQTVEELQAQVHSMDGAKGWFERRLKEAEESLQQQQQEQEE 545
Query: 195 TAALLEEARKRRLLEDSDSEDE 216
L++ R++ E E+E
Sbjct: 546 A---LKQCREQHAAELKGKEEE 564
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 45.4 bits (106), Expect = 7e-05
Identities = 37/146 (25%), Positives = 66/146 (45%), Gaps = 11/146 (7%)
Query: 103 GATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQ 162
G T +A +LL E+ ++ +++RE EE ++ +D ++ E L E + +
Sbjct: 592 GTTDREEATRLLAEKRRQAREQREREEQERRLQA----ERDKRMREEQLAREAEARAERE 647
Query: 163 RQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPL 222
+A E R+ +E+E + + Q++ E+ A EEA ++RL + +
Sbjct: 648 AEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQ------- 700
Query: 223 QPALRPNPTAILDEAPKPKRKVEVWE 248
Q R L+E K RK EV E
Sbjct: 701 QEQERQERRKRLEEIMKRTRKSEVSE 726
Score = 32.0 bits (71), Expect = 0.76
Identities = 37/156 (23%), Positives = 58/156 (37%), Gaps = 36/156 (23%)
Query: 180 EEERRRQQQEEDEQETAALLEEA--RKRRLLEDS-------------DSEDEAAPS---- 220
+++ ++ ++ E+E+E +AL E +KR+ L S + +A PS
Sbjct: 413 QKKEKKDKERENEKEKSALARERSLKKRQSLPASPRARLSASTASELSPKSKARPSSPST 472
Query: 221 ----PLQPALRPNPTAILDEAP--------KPKRKVEVWEQSVGSLGSRPP-----LSRL 263
P P P P L P PK +V E++ S + P R
Sbjct: 473 SWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSKRR 532
Query: 264 VVVKKAKADPDCSNGQPQAAPTPGAPQNRKEANPTP 299
+K A P P +PTP PQ + TP
Sbjct: 533 ASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETP 568
Score = 30.4 bits (67), Expect = 2.2
Identities = 18/46 (39%), Positives = 27/46 (58%), Gaps = 1/46 (2%)
Query: 173 LRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAA 218
LR+ +L E RR ++Q ++ A LEE R+R+ LE + EAA
Sbjct: 170 LREKQLQERRRRLEEQRLKAEQRRAALEE-RQRQKLEKNKERYEAA 214
Score = 29.6 bits (65), Expect = 3.8
Identities = 25/94 (26%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
Query: 117 EEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAM-LRQ 175
E ++ KER +E K L + K LE E K L +R+ ++ + + Q
Sbjct: 137 ERHKLAKERREERA----KYLAAK-KAVWLEKEEKAKALREKQLQERRRRLEEQRLKAEQ 191
Query: 176 HRLSEEERRRQQQEEDEQETAALLEEARKRRLLE 209
R + EER+RQ+ E++++ A ++ + K+ E
Sbjct: 192 RRAALEERQRQKLEKNKERYEAAIQRSVKKTWAE 225
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 45.1 bits (105), Expect = 9e-05
Identities = 32/118 (27%), Positives = 60/118 (50%), Gaps = 2/118 (1%)
Query: 73 IFRFYIKCTRCLAEITFKTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNN 132
I + ++K + ++ + D E ++ A R + EKL EE ++ ++ ++ +E
Sbjct: 321 ITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAERE-EKEKLKEEAKRAKEEAKKKKEEEK 379
Query: 133 PMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEE 190
+K E R K K E E E Q LK+ +++ EA L + R EEE+R +++E+
Sbjct: 380 ELKEKERREKREKDEKEKAEK-QRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEK 436
Score = 38.5 bits (88), Expect = 0.008
Identities = 33/135 (24%), Positives = 58/135 (42%), Gaps = 22/135 (16%)
Query: 117 EEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLRQH 176
E+ +++ +R+ E L +K+ R + KL+ E +E K + + +
Sbjct: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKEL--------- 381
Query: 177 RLSEEERRRQQQEEDEQETAA---LLEEARKRR-------LLEDSDSEDEAAPSPLQPAL 226
+E+ RR+++E+DE+E A L EE RK R L E E+E + +
Sbjct: 382 ---KEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRI 438
Query: 227 RPNPTAILDEAPKPK 241
+ I KPK
Sbjct: 439 KAEKAEITRFFQKPK 453
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 44.7 bits (104), Expect = 1e-04
Identities = 34/150 (22%), Positives = 68/150 (45%), Gaps = 7/150 (4%)
Query: 106 RNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQA 165
+ + +K L E+E+++Q E+E++ K+ E K + E + E +++++ Q+
Sbjct: 335 KELREQKELREQEEQMQ-EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 393
Query: 166 HVDFEAMLRQHRLSEEERRRQQQE------EDEQETAALLEEARKRRLLEDSDSEDEAAP 219
+ + RL E+E R ++QE E +E + E+ +K R E+ E+E
Sbjct: 394 DQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIR 453
Query: 220 SPLQPALRPNPTAILDEAPKPKRKVEVWEQ 249
+ T E K++ +WEQ
Sbjct: 454 EREKKMREEEETMREQEEKMQKQEENMWEQ 483
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/144 (23%), Positives = 71/144 (49%), Gaps = 8/144 (5%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD 168
Q EK+ E+EEK ++E + +E M E + + + +M + L E Q++ +
Sbjct: 615 QEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPE-----QKEKLWE 669
Query: 169 FEAMLRQHRLSEEERRRQQQEEDEQETAALLEEA--RKRRLLEDSDSEDEAAPSPLQPAL 226
E M Q ++ E+E + +QE+ E++T ++ +++ E+S E E + +
Sbjct: 670 HEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMM 729
Query: 227 RPNPTAILDEAPK-PKRKVEVWEQ 249
R + ++ K +++ E+WEQ
Sbjct: 730 REQEEKMQEQEEKMQEQEEEMWEQ 753
Score = 40.4 bits (93), Expect = 0.002
Identities = 33/143 (23%), Positives = 67/143 (46%), Gaps = 9/143 (6%)
Query: 108 FQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHV 167
++ EK+ E+E++ ++E + M+ E + D + ME QE K +Q +
Sbjct: 534 WRQEKMREQEDQMWEQEEK-------MRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMR 586
Query: 168 DFEAML-RQHRLSEEERRRQQQEEDEQETAALLEEARKRRL-LEDSDSEDEAAPSPLQPA 225
+ E M R+ ++ EEE ++QEE QE ++E ++ E+ E E +
Sbjct: 587 EEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEK 646
Query: 226 LRPNPTAILDEAPKPKRKVEVWE 248
+ + ++ P++K ++WE
Sbjct: 647 MWEQEEKMWEQQRLPEQKEKLWE 669
Score = 38.9 bits (89), Expect = 0.006
Identities = 33/158 (20%), Positives = 71/158 (44%), Gaps = 18/158 (11%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLE------NRTKDSKLEMEVLENLQELKDLNQ 162
Q EK+ E+EEK ++E + E M E R + K ++ E +QE + + +
Sbjct: 622 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQE 681
Query: 163 RQAHV-DFEAMLR-----------QHRLSEEERRRQQQEEDEQETAALLEEARKRRLLED 210
++ + + E M + Q ++ EEE R+++++ +E + E+ K + E+
Sbjct: 682 QEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEE 741
Query: 211 SDSEDEAAPSPLQPALRPNPTAILDEAPKPKRKVEVWE 248
E E + + + ++ P++K ++WE
Sbjct: 742 KMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWE 779
Score = 37.7 bits (86), Expect = 0.014
Identities = 35/143 (24%), Positives = 66/143 (46%), Gaps = 10/143 (6%)
Query: 109 QAEKLLEEEE--KRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAH 166
Q EK+ EEE +R +K RE+EE + E K K E + E QE K+ Q++
Sbjct: 442 QEEKMQEEERIREREKKMREEEET-----MREQEEKMQKQEENMWE--QEEKEWQQQRLP 494
Query: 167 VDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQPAL 226
E + Q ++ E+E + +QEE ++ + + K+ ++ E E + +
Sbjct: 495 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQ-EKKMWRQEKMREQEDQMWEQEEKM 553
Query: 227 RPNPTAILDEAPKPKRKVEVWEQ 249
R + D+ + ++K + E+
Sbjct: 554 RDQEQKMWDQEERMEKKTQEQEK 576
Score = 37.7 bits (86), Expect = 0.014
Identities = 31/153 (20%), Positives = 71/153 (46%), Gaps = 17/153 (11%)
Query: 109 QAEKLLEEEEKRVQKER----EDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQ 164
Q +++ E+EEK +E+ ++E + + E +T D + +M E ++E + + +
Sbjct: 542 QEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 601
Query: 165 AHVDFEAMLRQH--RLSEEERRRQQQEEDEQETAALLEEARKR------RLLEDSDSEDE 216
E M+R+ ++ E+E + Q+QEE E ++E ++ ++ E + E
Sbjct: 602 -----EEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWE 656
Query: 217 AAPSPLQPALRPNPTAILDEAPKPKRKVEVWEQ 249
P Q + ++ +++ ++WEQ
Sbjct: 657 QQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQ 689
Score = 37.4 bits (85), Expect = 0.018
Identities = 28/114 (24%), Positives = 57/114 (50%), Gaps = 10/114 (8%)
Query: 109 QAEKLLEEEEKRVQKEREDEEL-----NNPMKVLENRTKDSKLEMEVLENLQELKDLNQR 163
Q E+L E+EE+ ++E+ E++ M+ E +T+D + +M+ E ++E ++
Sbjct: 402 QDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRE----REK 457
Query: 164 QAHVDFEAMLRQ-HRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDE 216
+ + E M Q ++ ++E +QEE E + L E+ K E ++E
Sbjct: 458 KMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE 511
Score = 37.0 bits (84), Expect = 0.024
Identities = 33/146 (22%), Positives = 72/146 (49%), Gaps = 16/146 (10%)
Query: 106 RNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQA 165
R ++ ++ L E+E+R++++ + E M+ + + K + E +QE + + +R+
Sbjct: 398 RMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREK 457
Query: 166 HVDFEAMLRQHRLSEEERRRQQQEED--EQETAALLEEARKRRLLEDSDSEDEAAPSPLQ 223
+ E + + E+E + Q+QEE+ EQE +E +++RL E + E Q
Sbjct: 458 KMREE----EETMREQEEKMQKQEENMWEQEE----KEWQQQRLPEQKEKLWE------Q 503
Query: 224 PALRPNPTAILDEAPKPKRKVEVWEQ 249
++ I ++ K + + E+W Q
Sbjct: 504 EKMQEQEEKIWEQEEKIRDQEEMWGQ 529
Score = 35.8 bits (81), Expect = 0.053
Identities = 29/113 (25%), Positives = 55/113 (48%), Gaps = 5/113 (4%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDL---NQRQA 165
Q K+ E+EEK ++E+ E ++ E ++ K E E +QE ++ + +
Sbjct: 305 QEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKM 364
Query: 166 HVDFEAMLRQ-HRLSEEERR-RQQQEEDEQETAALLEEARKRRLLEDSDSEDE 216
E M RQ RL E+E++ R+Q+++ + + E+ + R E+ E E
Sbjct: 365 REQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 417
Score = 35.4 bits (80), Expect = 0.069
Identities = 32/114 (28%), Positives = 56/114 (49%), Gaps = 6/114 (5%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLEN-LQELKDLNQRQAHV 167
Q EK+ +EE+ ++E + E M E R ++ + E+ E L+E K+L +++ +
Sbjct: 291 QEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQM 350
Query: 168 DF--EAMLRQH-RLSEEERRRQQQEED--EQETAALLEEARKRRLLEDSDSEDE 216
E M Q ++ E+E + +QEE EQE +E + R E +DE
Sbjct: 351 QEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDE 404
Score = 35.0 bits (79), Expect = 0.090
Identities = 28/127 (22%), Positives = 60/127 (47%), Gaps = 8/127 (6%)
Query: 92 DPENTDYTMEHGATRNFQAEKLLEEEE--KRVQKEREDEELNNPMKVLENRTKDSKLEME 149
+ E + + + + EK+ EEE +R +K RE+EE+ + E K + E +
Sbjct: 688 EQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEM-----MREQEEKMQEQEEK 742
Query: 150 VLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLE 209
+ E +E+ + ++ + E M Q RL E++ + + E+ +++ +E + R E
Sbjct: 743 MQEQEEEMWEQEEKMWEQE-EKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEE 801
Query: 210 DSDSEDE 216
++E
Sbjct: 802 KMRGQEE 808
Score = 34.7 bits (78), Expect = 0.12
Identities = 29/121 (23%), Positives = 53/121 (43%), Gaps = 5/121 (4%)
Query: 93 PENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLE 152
PE + EH + + EK+ E+EEK +E + M+ E + + + +M E
Sbjct: 771 PEQKEKLWEHEKMQ--EQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQE 828
Query: 153 NL---QELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLE 209
QE K Q + E + + +EE+ R+Q+E+ + + E+ K R E
Sbjct: 829 EKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQE 888
Query: 210 D 210
+
Sbjct: 889 E 889
Score = 33.5 bits (75), Expect = 0.26
Identities = 30/154 (19%), Positives = 73/154 (47%), Gaps = 18/154 (11%)
Query: 108 FQAEKLLEEEEKRVQKE-----REDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQ 162
++ E+ L E+EK+++K+ R++E L + R ++ K+ + ++ K+L +
Sbjct: 275 WRQEEELREQEKKIRKQEEKMWRQEERLREQEGKM--REQEEKMWRQEKRLREQEKELRE 332
Query: 163 RQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPL 222
++ + + LR+ +EE+ ++Q+E+ ++ + E+ K E+ E E
Sbjct: 333 QEKELREQKELRE----QEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ 388
Query: 223 QPALRPNPTAILDEAPKPKRKVE-------VWEQ 249
+ +R + ++ + + K E +WEQ
Sbjct: 389 EQKMRDQEERMWEQDERLREKEERMREQEKMWEQ 422
Score = 32.3 bits (72), Expect = 0.58
Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 4/82 (4%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD 168
Q EK+ E+EEK ++E E E M E + + + E E L E + + +++ +
Sbjct: 732 QEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWE 791
Query: 169 FEAMLRQHRLSEEERRRQQQEE 190
E +R +EE+ R Q+E+
Sbjct: 792 QEEKMR----DQEEKMRGQEEK 809
Score = 31.2 bits (69), Expect = 1.3
Identities = 25/111 (22%), Positives = 53/111 (47%), Gaps = 9/111 (8%)
Query: 109 QAEKLLEEEEKRVQKE---REDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQA 165
+A+ LL + + +E R++EEL E K K E ++ + L++ +
Sbjct: 257 RAKFLLPQVQTNTLQEEMWRQEEELR------EQEKKIRKQEEKMWRQEERLREQEGKMR 310
Query: 166 HVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDE 216
+ + ++ RL E+E+ ++QE++ +E L E+ + + E+ E E
Sbjct: 311 EQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQE 361
Score = 30.8 bits (68), Expect = 1.7
Identities = 29/157 (18%), Positives = 64/157 (40%), Gaps = 11/157 (7%)
Query: 94 ENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLEN 153
E + + T Q E +EEE R Q++ K+ + K + E + E
Sbjct: 256 ERAKFLLPQVQTNTLQEEMWRQEEELREQEK----------KIRKQEEKMWRQEERLREQ 305
Query: 154 LQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDS 213
++++ ++ + ++ L E+E+ ++Q+E ++ + E+ K E+
Sbjct: 306 EGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMR 365
Query: 214 EDEAAPSPLQPALRPNPTAILDEAPKPKRKVE-VWEQ 249
E E + L + ++ K + + E +WEQ
Sbjct: 366 EQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ 402
Score = 29.3 bits (64), Expect = 4.9
Identities = 43/167 (25%), Positives = 73/167 (43%), Gaps = 30/167 (17%)
Query: 104 ATRNFQAEKLLEEEEKRVQKERE------------DEELNNPMKVLENRTKDSKLEM-EV 150
+TR+ +A++ +EE + KER+ +EEL L+ + ++ E E+
Sbjct: 189 STRHKKADRYIEE----LTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEI 244
Query: 151 LENLQELKD--------LNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEA 202
N++ELK L Q Q + E M RQ EEE R Q+++ +QE +E
Sbjct: 245 QLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQ----EEELREQEKKIRKQEEKMWRQEE 300
Query: 203 RKRRLLEDSDSEDEAAPSPLQPALRPNPTAILDEAPKPKRKVEVWEQ 249
R R E E E + LR + ++ + + + E+ EQ
Sbjct: 301 RLRE-QEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQ 346
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 44.3 bits (103), Expect = 1e-04
Identities = 33/116 (28%), Positives = 61/116 (52%), Gaps = 11/116 (9%)
Query: 101 EHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLE-NLQELKD 159
++ A+R F+ ++ LE+E K++Q + + + +K L+ + SK E++ LE L+E K
Sbjct: 208 QNEASREFRKKEKLEKELKQIQADMDSRQ--TEIKALQQYVQKSKEELQKLEQQLKEQKI 265
Query: 160 LNQRQAHVDFEAMLRQHRLSEE--------ERRRQQQEEDEQETAALLEEARKRRL 207
LN+R A + +R +L +E E+ Q+ ++ E A EE + RL
Sbjct: 266 LNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRL 321
Score = 31.2 bits (69), Expect = 1.3
Identities = 29/121 (23%), Positives = 58/121 (47%), Gaps = 16/121 (13%)
Query: 111 EKLLEEEEKRVQKEREDEELNNPM----KVLENRTKDSKLEMEVLENLQELKDLNQRQAH 166
E L + E++ + ER EE + + + ++ R ++ E E L+ K+L Q QA
Sbjct: 174 ESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLE--KELKQIQAD 231
Query: 167 VD-----FEAMLRQHRLSEEERRRQQQEEDEQE-----TAALLEEARKRRLLEDSDSEDE 216
+D +A+ + + S+EE ++ +Q+ EQ+ A LE+ + R ++E
Sbjct: 232 MDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQH 291
Query: 217 A 217
+
Sbjct: 292 S 292
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 43.9 bits (102), Expect = 2e-04
Identities = 27/89 (30%), Positives = 45/89 (50%), Gaps = 4/89 (4%)
Query: 112 KLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEA 171
+LL+E+E Q +E ++ +SK+E+E L++L E N + H+ E
Sbjct: 1667 QLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTE----NLTKEHLMLEE 1722
Query: 172 MLRQHRLSEEERRRQQQEEDEQETAALLE 200
LR RL ++ RR + E D + A +LE
Sbjct: 1723 ELRNLRLEYDDLRRGRSEADSDKNATILE 1751
Score = 31.6 bits (70), Expect = 1.00
Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 11/116 (9%)
Query: 117 EEKRVQKEREDEELNNPMKVLENRTKDSKLE--------MEVLENLQELKDLNQRQAHVD 168
+E +QKE + + L N + L +D K E ++ E + ++ +Q
Sbjct: 1222 KEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACG 1281
Query: 169 FEAMLRQHRLSEEERR-RQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQ 223
E M ++ L E ++ QQ+ ED LEEA K ++D + E E + Q
Sbjct: 1282 SEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAAK--TIQDKNKEIERLKAEFQ 1335
Score = 30.4 bits (67), Expect = 2.2
Identities = 30/137 (21%), Positives = 58/137 (42%), Gaps = 23/137 (16%)
Query: 94 ENTDYTMEHGATRNFQAEKLLEEEE-------------KRVQKEREDEELNNPMKVLENR 140
++ D T + + Q +K EEE KR + E E E + +K +
Sbjct: 1552 KDQDITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIK 1611
Query: 141 TKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLE 200
+ ++E +++ + + RQ + LR+ + ++EE RR E
Sbjct: 1612 ITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSE----------V 1661
Query: 201 EARKRRLLEDSDSEDEA 217
EA +R+LL++ +S +A
Sbjct: 1662 EALRRQLLQEQESVKQA 1678
Score = 29.6 bits (65), Expect = 3.8
Identities = 20/98 (20%), Positives = 45/98 (45%), Gaps = 1/98 (1%)
Query: 117 EEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLRQH 176
E+ + K+R +++L VL+ ++ + E L L + +RQ + E++ + H
Sbjct: 1620 EQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQAH 1679
Query: 177 RLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSE 214
L E ++ +++ + +E R + L E+ E
Sbjct: 1680 -LRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKE 1716
Score = 29.6 bits (65), Expect = 3.8
Identities = 36/119 (30%), Positives = 53/119 (44%), Gaps = 29/119 (24%)
Query: 112 KLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQ--------- 162
K+LE+++ R+Q R ++ELN LE T+ K +E E Q DLNQ
Sbjct: 1820 KVLEQDKARLQ--RLEDELNRAKSTLEAETR-VKQRLEC-EKQQIQNDLNQWKTQYSRKE 1875
Query: 163 ---RQAHVDFEAMLRQ--------HRLSEE-----ERRRQQQEEDEQETAALLEEARKR 205
R+ + E R+ RL E ER R++ E+ +ET + LE R R
Sbjct: 1876 EAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRETQSQLETERSR 1934
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 43.9 bits (102), Expect = 2e-04
Identities = 52/192 (27%), Positives = 82/192 (42%), Gaps = 29/192 (15%)
Query: 115 EEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLR 174
EEEE+ ++E E+EE E +D + E E E E ++ + + +FE
Sbjct: 889 EEEEEEEEEEEEEEE--------EEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEE--E 938
Query: 175 QHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSP--LQPALRP--NP 230
+ L EEE ++EE+E LEE +E AP P L PAL P +P
Sbjct: 939 EGELEEEEEEEDEEEEEE------LEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESP 992
Query: 231 TAILDE-APKPKRKVEVWE---QSVGSLGSRPPLSRLVVVKKAKADPDCSNGQPQAAPTP 286
+ E P+P +EV E + + P L+ + + + + + G+ AA P
Sbjct: 993 PKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVERE---GESPAAGPP 1049
Query: 287 GAPQNRKEANPT 298
PQ E P+
Sbjct: 1050 --PQELVEEEPS 1059
Score = 32.0 bits (71), Expect = 0.76
Identities = 47/185 (25%), Positives = 67/185 (36%), Gaps = 26/185 (14%)
Query: 92 DPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVL 151
+ E D+ E + E+ EEEE + E E+ EL E +D + E
Sbjct: 904 EEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEE-----EEEEEDEEEE---- 954
Query: 152 ENLQELKDLNQRQAHVDFE-----AMLRQHRLSEEERRRQQQEEDEQETAALLE-EARKR 205
E L+E++DL A + E L E + Q E E E LLE E
Sbjct: 955 EELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGT 1014
Query: 206 RLLEDSDSEDEAAPSPL-----------QPALRPNPTAILDEAPKPKRKVEVWEQSVGSL 254
+D+ AP L PA P P +++E P + E GS
Sbjct: 1015 EEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSD 1074
Query: 255 GSRPP 259
+PP
Sbjct: 1075 KVQPP 1079
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 43.9 bits (102), Expect = 2e-04
Identities = 30/117 (25%), Positives = 57/117 (48%)
Query: 90 KTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEME 149
K D E + + + +K L E+ R +++ E+E L + ++LE+E
Sbjct: 1888 KADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELE 1947
Query: 150 VLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRR 206
+ +D + + + EA ++ +EEERRR++ EE Q++ A EEA ++R
Sbjct: 1948 LGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2004
Score = 40.4 bits (93), Expect = 0.002
Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 10/134 (7%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD 168
Q E+ +E+E+ ++++ +DE E + + ++E E + +++ +RQ +
Sbjct: 2504 QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE 2563
Query: 169 FEAMLRQHRLSEEERRRQQQEE---DE----QETAALLEEARKRRLLEDSDSEDEAAPSP 221
+Q L + E++R+QQEE +E +E LLEE + L + SE+ A
Sbjct: 2564 EGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL---AHSEEVTASQV 2620
Query: 222 LQPALRPNPTAILD 235
PN LD
Sbjct: 2621 AATKTLPNGRDALD 2634
Score = 37.4 bits (85), Expect = 0.018
Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 14/129 (10%)
Query: 110 AEKLLEEEEKR-----VQKERE-DEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQR 163
A+K L+ EEK QKE+E + L VL+ +++ E +E + +R
Sbjct: 2043 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2102
Query: 164 QAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQ 223
+A Q R EE R +Q +EQ A +A +L ++++ E Q
Sbjct: 2103 EA--------AQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQ 2154
Query: 224 PALRPNPTA 232
ALR A
Sbjct: 2155 AALRQKQAA 2163
Score = 35.8 bits (81), Expect = 0.053
Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 6/104 (5%)
Query: 109 QAEKLLEEEEKRVQK--EREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAH 166
Q E+LL+E + Q +D L + + + K +L + + Q+L++ QRQ
Sbjct: 2480 QQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQ 2539
Query: 167 VDFEAMLRQHRLSEEERRRQQQEED----EQETAALLEEARKRR 206
+ R EE RRRQ + E+ +QE LE+ R+++
Sbjct: 2540 QMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2583
Score = 33.5 bits (75), Expect = 0.26
Identities = 30/121 (24%), Positives = 55/121 (45%), Gaps = 8/121 (6%)
Query: 109 QAEKLLEEEEKRVQ-KEREDEELNNPMKVLENRTKDSKLEMEVLENLQ-----ELKDLNQ 162
+ ++L + E +Q K R+ E +E + +L++E E + EL+ L
Sbjct: 1421 ELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRA 1480
Query: 163 RQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPL 222
R EA RQ + E RRQ Q+E +++ A +E A + + ++ E + A L
Sbjct: 1481 RAEEA--EAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQAL 1538
Query: 223 Q 223
+
Sbjct: 1539 E 1539
Score = 33.5 bits (75), Expect = 0.26
Identities = 31/125 (24%), Positives = 54/125 (43%), Gaps = 10/125 (8%)
Query: 104 ATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDS---KLEM------EVLENL 154
A + Q E+ L+EE V + RE+ E + R ++ +LE E L
Sbjct: 1586 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1645
Query: 155 QELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLE-EARKRRLLEDSDS 213
+ +++ Q+++ EA ++ E RRR + EE L E E K+R L + +
Sbjct: 1646 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1705
Query: 214 EDEAA 218
+ A
Sbjct: 1706 QQRLA 1710
Score = 33.1 bits (74), Expect = 0.34
Identities = 33/135 (24%), Positives = 64/135 (47%), Gaps = 12/135 (8%)
Query: 117 EEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLE-NLQELKDLNQRQAHVDFEAMLRQ 175
E +R Q + + E L + LE + + E ++L+ +E++ + Q Q + +A L+Q
Sbjct: 2435 EIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQA-LQQ 2493
Query: 176 HRLSEEERRRQQQEEDEQETAALL-----EEARKRRLLEDSDSEDEAAPSPLQPALRPNP 230
LSE++ Q++ EQE A L E A+ ++L E+ + + R
Sbjct: 2494 SFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE-----RQRL 2548
Query: 231 TAILDEAPKPKRKVE 245
A ++EA + + + E
Sbjct: 2549 VASMEEARRRQHEAE 2563
Score = 32.3 bits (72), Expect = 0.58
Identities = 29/119 (24%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Query: 101 EHGATRNFQAEKLLEEEEKRVQKE--REDEELNNPMKVLENRTKDSKLEMEVLENLQELK 158
E A + +AE+ EE E+ +++ + +E L ++ E + S + E + +E +
Sbjct: 1611 ERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAE 1670
Query: 159 DLNQRQAHVDFEAMLRQHRLSEEERRRQQQEED---EQETAALLEEARKRRLLEDSDSE 214
+R+ + +A+ RQ L+E+E +Q+Q + +Q AA E R R E + +
Sbjct: 1671 REARRRGKAEEQAV-RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1728
Score = 31.6 bits (70), Expect = 1.00
Identities = 37/152 (24%), Positives = 60/152 (39%), Gaps = 15/152 (9%)
Query: 104 ATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQR 163
A Q EEE R +K +E KV E R + E E LQ ++ Q+
Sbjct: 1986 AEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQK 2045
Query: 164 QAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSD-----SEDEAA 218
+ + +A + E+E ++ Q+E E RR E+++ +E EAA
Sbjct: 2046 RLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAA 2105
Query: 219 PSPLQPALRPNPTAILDEAPKPKRKVEVWEQS 250
S Q ++EA + K+ E Q+
Sbjct: 2106 QSRRQ----------VEEAERLKQSAEEQAQA 2127
Score = 31.2 bits (69), Expect = 1.3
Identities = 23/114 (20%), Positives = 52/114 (45%), Gaps = 19/114 (16%)
Query: 114 LEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAML 173
+EEEE+ +++R +E E L ++ + ++ A +A
Sbjct: 1344 MEEEERLAEQQRAEER-------------------ERLAEVEAALEKQRQLAEAHAQAKA 1384
Query: 174 RQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQPALR 227
+ R ++E ++R Q+E +E AA+ + +KR + E+ +++ + +Q R
Sbjct: 1385 QAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKAR 1438
Score = 31.2 bits (69), Expect = 1.3
Identities = 35/135 (25%), Positives = 59/135 (43%), Gaps = 26/135 (19%)
Query: 109 QAEKLLEEE------------EKRVQKEREDEELNNPMKVL---------ENRTKDSKLE 147
Q +LLEEE +KR + E E ++ M+VL E+R+ K +
Sbjct: 1727 QQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSK 1786
Query: 148 MEVLENLQELKDLNQRQAHVDF--EAMLRQHRLSEEERRRQQQEEDE---QETAALLEEA 202
+ ++L + A + E RQ +L+EE+ RQ+ E + ++ AA+ E
Sbjct: 1787 QRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEAT 1846
Query: 203 RKRRLLEDSDSEDEA 217
R + E + E EA
Sbjct: 1847 RLKTEAEIALKEKEA 1861
Score = 31.2 bits (69), Expect = 1.3
Identities = 34/141 (24%), Positives = 65/141 (46%), Gaps = 15/141 (10%)
Query: 115 EEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDF----- 169
E EE RVQ ERE + ++ E + ++ + + Q + +++A +
Sbjct: 2092 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2151
Query: 170 --EAMLRQHRL--SEEERRRQQQEEDEQETAALLEEARKRRL-LEDSDSEDEAAPSPLQP 224
+A LRQ + +E E+ ++ E+ ++ A + +E RL LE++D + LQ
Sbjct: 2152 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ- 2210
Query: 225 ALRPNPTAILDEAPKPKRKVE 245
L+ T EA + + +VE
Sbjct: 2211 RLKAEAT----EAARQRSQVE 2227
Score = 30.8 bits (68), Expect = 1.7
Identities = 35/137 (25%), Positives = 63/137 (45%), Gaps = 30/137 (21%)
Query: 109 QAEKLLEEEEKRVQK----EREDEELNNPMKVLENRTKDSKLEMEVLEN----------- 153
Q + LLEE E+ +K +R ++ N +K E + K ++E + +
Sbjct: 1250 QEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGS 1309
Query: 154 ---LQELKDLNQRQAHVDFEAMLRQH---------RLSEEERRRQQQEEDEQETAALLEE 201
+QE DL R + + + Q+ R+ EEER +QQ +E+E A +E
Sbjct: 1310 ESVIQEYVDL--RTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEA 1367
Query: 202 A-RKRRLLEDSDSEDEA 217
A K+R L ++ ++ +A
Sbjct: 1368 ALEKQRQLAEAHAQAKA 1384
Score = 30.8 bits (68), Expect = 1.7
Identities = 44/214 (20%), Positives = 81/214 (37%), Gaps = 31/214 (14%)
Query: 90 KTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEME 149
+++ E+T + E + +L EEE+R + +E + + E + K +E
Sbjct: 1952 RSNAEDTLRSKEQAELEAARQRQLAAEEERR--RREAEERVQKSLAAEEEAARQRKAALE 2009
Query: 150 VLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLE 209
+E L+ ++ E R R++ E++ L +EA ++RL
Sbjct: 2010 EVERLKA--------------------KVEEARRLRERAEQESARQLQLAQEAAQKRLQA 2049
Query: 210 DSDSEDEAA---PSPLQPALRPNPTAILD----EAPKPKRKVEVWEQSVGSLGSRPPLSR 262
+ + A LQ L+ ++LD EA +R E E++ SR
Sbjct: 2050 EEKAHAFAVQQKEQELQQTLQ-QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR 2108
Query: 263 LVVVKKAKADPDC-SNGQPQAAPTPGAPQNRKEA 295
V + + Q +A A + RKEA
Sbjct: 2109 RQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2142
Score = 30.8 bits (68), Expect = 1.7
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 13/108 (12%)
Query: 110 AEKLLEEEEKRV------------QKEREDEELNNPMKVLENRTKD-SKLEMEVLENLQE 156
AEKL +E E+ QK+ D E+ K E + +++E E+ +
Sbjct: 2135 AEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2194
Query: 157 LKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARK 204
L++ + ++ +D E + +E R+R Q EE+ +EE K
Sbjct: 2195 LEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSK 2242
Score = 30.4 bits (67), Expect = 2.2
Identities = 31/105 (29%), Positives = 50/105 (47%), Gaps = 13/105 (12%)
Query: 110 AEKLLEEEEKRVQKE---REDEELNNPMKVLEN----RTKDSKLEM--EVLENLQ----E 156
AEK+L+E+ + VQ+ + + EL K L R ++ K +M ++ E Q
Sbjct: 2308 AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT 2367
Query: 157 LKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEE 201
L+ QRQ + EA + R++E R + + EED Q EE
Sbjct: 2368 LEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEE 2412
Score = 29.6 bits (65), Expect = 3.8
Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 6/93 (6%)
Query: 113 LLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAM 172
L EE EK Q E L+ + + ++L E+L + + L ++ +A+
Sbjct: 2266 LQEEAEKMKQVAEEAARLSVAAQ------EAARLRQLAEEDLAQQRALAEKMLKEKMQAV 2319
Query: 173 LRQHRLSEEERRRQQQEEDEQETAALLEEARKR 205
RL E QQQ+E QE A L+E +++
Sbjct: 2320 QEATRLKAEAELLQQQKELAQEQARRLQEDKEQ 2352
Score = 29.3 bits (64), Expect = 4.9
Identities = 26/111 (23%), Positives = 50/111 (45%), Gaps = 3/111 (2%)
Query: 116 EEEKRVQKEREDEELNNPMKVLENRTKDS-KLEMEVLENLQELKDLNQRQAHVDFEAMLR 174
EE+ Q+E ++EL ++ E + E E++ E + Q++ ++ E
Sbjct: 1680 EEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1739
Query: 175 QHRLSEEERRRQQQEEDEQETAALLEE--ARKRRLLEDSDSEDEAAPSPLQ 223
Q + ++RQ+ E + + A +E A K R E+S S E + L+
Sbjct: 1740 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLE 1790
Score = 28.5 bits (62), Expect = 8.4
Identities = 27/110 (24%), Positives = 52/110 (47%), Gaps = 9/110 (8%)
Query: 112 KLLEEEEKRVQK----EREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHV 167
+L EE E+R Q+ ER EE ++ + + ++ E + + K L Q +A
Sbjct: 1605 QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK 1664
Query: 168 DFEAMLRQHRL---SEEERRRQQQ--EEDEQETAALLEEARKRRLLEDSD 212
E R+ R +EE+ RQ++ E++ ++ L E ++RL + +
Sbjct: 1665 QKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQE 1714
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 43.9 bits (102), Expect = 2e-04
Identities = 30/117 (25%), Positives = 57/117 (48%)
Query: 90 KTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEME 149
K D E + + + +K L E+ R +++ E+E L + ++LE+E
Sbjct: 1892 KADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELE 1951
Query: 150 VLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRR 206
+ +D + + + EA ++ +EEERRR++ EE Q++ A EEA ++R
Sbjct: 1952 LGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2008
Score = 40.4 bits (93), Expect = 0.002
Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 10/134 (7%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD 168
Q E+ +E+E+ ++++ +DE E + + ++E E + +++ +RQ +
Sbjct: 2508 QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE 2567
Query: 169 FEAMLRQHRLSEEERRRQQQEE---DE----QETAALLEEARKRRLLEDSDSEDEAAPSP 221
+Q L + E++R+QQEE +E +E LLEE + L + SE+ A
Sbjct: 2568 EGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL---AHSEEVTASQV 2624
Query: 222 LQPALRPNPTAILD 235
PN LD
Sbjct: 2625 AATKTLPNGRDALD 2638
Score = 37.4 bits (85), Expect = 0.018
Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 14/129 (10%)
Query: 110 AEKLLEEEEKR-----VQKERE-DEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQR 163
A+K L+ EEK QKE+E + L VL+ +++ E +E + +R
Sbjct: 2047 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2106
Query: 164 QAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQ 223
+A Q R EE R +Q +EQ A +A +L ++++ E Q
Sbjct: 2107 EA--------AQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQ 2158
Query: 224 PALRPNPTA 232
ALR A
Sbjct: 2159 AALRQKQAA 2167
Score = 35.8 bits (81), Expect = 0.053
Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 6/104 (5%)
Query: 109 QAEKLLEEEEKRVQK--EREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAH 166
Q E+LL+E + Q +D L + + + K +L + + Q+L++ QRQ
Sbjct: 2484 QQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQ 2543
Query: 167 VDFEAMLRQHRLSEEERRRQQQEED----EQETAALLEEARKRR 206
+ R EE RRRQ + E+ +QE LE+ R+++
Sbjct: 2544 QMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2587
Score = 33.5 bits (75), Expect = 0.26
Identities = 30/121 (24%), Positives = 55/121 (45%), Gaps = 8/121 (6%)
Query: 109 QAEKLLEEEEKRVQ-KEREDEELNNPMKVLENRTKDSKLEMEVLENLQ-----ELKDLNQ 162
+ ++L + E +Q K R+ E +E + +L++E E + EL+ L
Sbjct: 1425 ELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRA 1484
Query: 163 RQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPL 222
R EA RQ + E RRQ Q+E +++ A +E A + + ++ E + A L
Sbjct: 1485 RAEEA--EAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQAL 1542
Query: 223 Q 223
+
Sbjct: 1543 E 1543
Score = 33.5 bits (75), Expect = 0.26
Identities = 31/125 (24%), Positives = 54/125 (43%), Gaps = 10/125 (8%)
Query: 104 ATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDS---KLEM------EVLENL 154
A + Q E+ L+EE V + RE+ E + R ++ +LE E L
Sbjct: 1590 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1649
Query: 155 QELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLE-EARKRRLLEDSDS 213
+ +++ Q+++ EA ++ E RRR + EE L E E K+R L + +
Sbjct: 1650 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1709
Query: 214 EDEAA 218
+ A
Sbjct: 1710 QQRLA 1714
Score = 33.1 bits (74), Expect = 0.34
Identities = 33/135 (24%), Positives = 64/135 (47%), Gaps = 12/135 (8%)
Query: 117 EEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLE-NLQELKDLNQRQAHVDFEAMLRQ 175
E +R Q + + E L + LE + + E ++L+ +E++ + Q Q + +A L+Q
Sbjct: 2439 EIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQA-LQQ 2497
Query: 176 HRLSEEERRRQQQEEDEQETAALL-----EEARKRRLLEDSDSEDEAAPSPLQPALRPNP 230
LSE++ Q++ EQE A L E A+ ++L E+ + + R
Sbjct: 2498 SFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE-----RQRL 2552
Query: 231 TAILDEAPKPKRKVE 245
A ++EA + + + E
Sbjct: 2553 VASMEEARRRQHEAE 2567
Score = 32.3 bits (72), Expect = 0.58
Identities = 29/119 (24%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Query: 101 EHGATRNFQAEKLLEEEEKRVQKE--REDEELNNPMKVLENRTKDSKLEMEVLENLQELK 158
E A + +AE+ EE E+ +++ + +E L ++ E + S + E + +E +
Sbjct: 1615 ERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAE 1674
Query: 159 DLNQRQAHVDFEAMLRQHRLSEEERRRQQQEED---EQETAALLEEARKRRLLEDSDSE 214
+R+ + +A+ RQ L+E+E +Q+Q + +Q AA E R R E + +
Sbjct: 1675 REARRRGKAEEQAV-RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1732
Score = 31.6 bits (70), Expect = 1.00
Identities = 37/152 (24%), Positives = 60/152 (39%), Gaps = 15/152 (9%)
Query: 104 ATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQR 163
A Q EEE R +K +E KV E R + E E LQ ++ Q+
Sbjct: 1990 AEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQK 2049
Query: 164 QAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSD-----SEDEAA 218
+ + +A + E+E ++ Q+E E RR E+++ +E EAA
Sbjct: 2050 RLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAA 2109
Query: 219 PSPLQPALRPNPTAILDEAPKPKRKVEVWEQS 250
S Q ++EA + K+ E Q+
Sbjct: 2110 QSRRQ----------VEEAERLKQSAEEQAQA 2131
Score = 31.2 bits (69), Expect = 1.3
Identities = 23/114 (20%), Positives = 52/114 (45%), Gaps = 19/114 (16%)
Query: 114 LEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAML 173
+EEEE+ +++R +E E L ++ + ++ A +A
Sbjct: 1348 MEEEERLAEQQRAEER-------------------ERLAEVEAALEKQRQLAEAHAQAKA 1388
Query: 174 RQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQPALR 227
+ R ++E ++R Q+E +E AA+ + +KR + E+ +++ + +Q R
Sbjct: 1389 QAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKAR 1442
Score = 31.2 bits (69), Expect = 1.3
Identities = 35/135 (25%), Positives = 59/135 (43%), Gaps = 26/135 (19%)
Query: 109 QAEKLLEEE------------EKRVQKEREDEELNNPMKVL---------ENRTKDSKLE 147
Q +LLEEE +KR + E E ++ M+VL E+R+ K +
Sbjct: 1731 QQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSK 1790
Query: 148 MEVLENLQELKDLNQRQAHVDF--EAMLRQHRLSEEERRRQQQEEDE---QETAALLEEA 202
+ ++L + A + E RQ +L+EE+ RQ+ E + ++ AA+ E
Sbjct: 1791 QRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEAT 1850
Query: 203 RKRRLLEDSDSEDEA 217
R + E + E EA
Sbjct: 1851 RLKTEAEIALKEKEA 1865
Score = 31.2 bits (69), Expect = 1.3
Identities = 34/141 (24%), Positives = 65/141 (46%), Gaps = 15/141 (10%)
Query: 115 EEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDF----- 169
E EE RVQ ERE + ++ E + ++ + + Q + +++A +
Sbjct: 2096 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2155
Query: 170 --EAMLRQHRL--SEEERRRQQQEEDEQETAALLEEARKRRL-LEDSDSEDEAAPSPLQP 224
+A LRQ + +E E+ ++ E+ ++ A + +E RL LE++D + LQ
Sbjct: 2156 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ- 2214
Query: 225 ALRPNPTAILDEAPKPKRKVE 245
L+ T EA + + +VE
Sbjct: 2215 RLKAEAT----EAARQRSQVE 2231
Score = 30.8 bits (68), Expect = 1.7
Identities = 35/137 (25%), Positives = 63/137 (45%), Gaps = 30/137 (21%)
Query: 109 QAEKLLEEEEKRVQK----EREDEELNNPMKVLENRTKDSKLEMEVLEN----------- 153
Q + LLEE E+ +K +R ++ N +K E + K ++E + +
Sbjct: 1254 QEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGS 1313
Query: 154 ---LQELKDLNQRQAHVDFEAMLRQH---------RLSEEERRRQQQEEDEQETAALLEE 201
+QE DL R + + + Q+ R+ EEER +QQ +E+E A +E
Sbjct: 1314 ESVIQEYVDL--RTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEA 1371
Query: 202 A-RKRRLLEDSDSEDEA 217
A K+R L ++ ++ +A
Sbjct: 1372 ALEKQRQLAEAHAQAKA 1388
Score = 30.8 bits (68), Expect = 1.7
Identities = 44/214 (20%), Positives = 81/214 (37%), Gaps = 31/214 (14%)
Query: 90 KTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEME 149
+++ E+T + E + +L EEE+R + +E + + E + K +E
Sbjct: 1956 RSNAEDTLRSKEQAELEAARQRQLAAEEERR--RREAEERVQKSLAAEEEAARQRKAALE 2013
Query: 150 VLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLE 209
+E L+ ++ E R R++ E++ L +EA ++RL
Sbjct: 2014 EVERLKA--------------------KVEEARRLRERAEQESARQLQLAQEAAQKRLQA 2053
Query: 210 DSDSEDEAA---PSPLQPALRPNPTAILD----EAPKPKRKVEVWEQSVGSLGSRPPLSR 262
+ + A LQ L+ ++LD EA +R E E++ SR
Sbjct: 2054 EEKAHAFAVQQKEQELQQTLQ-QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR 2112
Query: 263 LVVVKKAKADPDC-SNGQPQAAPTPGAPQNRKEA 295
V + + Q +A A + RKEA
Sbjct: 2113 RQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2146
Score = 30.8 bits (68), Expect = 1.7
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 13/108 (12%)
Query: 110 AEKLLEEEEKRV------------QKEREDEELNNPMKVLENRTKD-SKLEMEVLENLQE 156
AEKL +E E+ QK+ D E+ K E + +++E E+ +
Sbjct: 2139 AEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2198
Query: 157 LKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARK 204
L++ + ++ +D E + +E R+R Q EE+ +EE K
Sbjct: 2199 LEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSK 2246
Score = 30.4 bits (67), Expect = 2.2
Identities = 31/105 (29%), Positives = 50/105 (47%), Gaps = 13/105 (12%)
Query: 110 AEKLLEEEEKRVQKE---REDEELNNPMKVLEN----RTKDSKLEM--EVLENLQ----E 156
AEK+L+E+ + VQ+ + + EL K L R ++ K +M ++ E Q
Sbjct: 2312 AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT 2371
Query: 157 LKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEE 201
L+ QRQ + EA + R++E R + + EED Q EE
Sbjct: 2372 LEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEE 2416
Score = 29.6 bits (65), Expect = 3.8
Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 6/93 (6%)
Query: 113 LLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAM 172
L EE EK Q E L+ + + ++L E+L + + L ++ +A+
Sbjct: 2270 LQEEAEKMKQVAEEAARLSVAAQ------EAARLRQLAEEDLAQQRALAEKMLKEKMQAV 2323
Query: 173 LRQHRLSEEERRRQQQEEDEQETAALLEEARKR 205
RL E QQQ+E QE A L+E +++
Sbjct: 2324 QEATRLKAEAELLQQQKELAQEQARRLQEDKEQ 2356
Score = 29.3 bits (64), Expect = 4.9
Identities = 26/111 (23%), Positives = 50/111 (45%), Gaps = 3/111 (2%)
Query: 116 EEEKRVQKEREDEELNNPMKVLENRTKDS-KLEMEVLENLQELKDLNQRQAHVDFEAMLR 174
EE+ Q+E ++EL ++ E + E E++ E + Q++ ++ E
Sbjct: 1684 EEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1743
Query: 175 QHRLSEEERRRQQQEEDEQETAALLEE--ARKRRLLEDSDSEDEAAPSPLQ 223
Q + ++RQ+ E + + A +E A K R E+S S E + L+
Sbjct: 1744 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLE 1794
Score = 28.5 bits (62), Expect = 8.4
Identities = 27/110 (24%), Positives = 52/110 (47%), Gaps = 9/110 (8%)
Query: 112 KLLEEEEKRVQK----EREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHV 167
+L EE E+R Q+ ER EE ++ + + ++ E + + K L Q +A
Sbjct: 1609 QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK 1668
Query: 168 DFEAMLRQHRL---SEEERRRQQQ--EEDEQETAALLEEARKRRLLEDSD 212
E R+ R +EE+ RQ++ E++ ++ L E ++RL + +
Sbjct: 1669 QKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQE 1718
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 43.9 bits (102), Expect = 2e-04
Identities = 30/117 (25%), Positives = 57/117 (48%)
Query: 90 KTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEME 149
K D E + + + +K L E+ R +++ E+E L + ++LE+E
Sbjct: 1888 KADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELE 1947
Query: 150 VLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRR 206
+ +D + + + EA ++ +EEERRR++ EE Q++ A EEA ++R
Sbjct: 1948 LGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2004
Score = 40.4 bits (93), Expect = 0.002
Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 10/134 (7%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD 168
Q E+ +E+E+ ++++ +DE E + + ++E E + +++ +RQ +
Sbjct: 2504 QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE 2563
Query: 169 FEAMLRQHRLSEEERRRQQQEE---DE----QETAALLEEARKRRLLEDSDSEDEAAPSP 221
+Q L + E++R+QQEE +E +E LLEE + L + SE+ A
Sbjct: 2564 EGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL---AHSEEVTASQV 2620
Query: 222 LQPALRPNPTAILD 235
PN LD
Sbjct: 2621 AATKTLPNGRDALD 2634
Score = 37.4 bits (85), Expect = 0.018
Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 14/129 (10%)
Query: 110 AEKLLEEEEKR-----VQKERE-DEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQR 163
A+K L+ EEK QKE+E + L VL+ +++ E +E + +R
Sbjct: 2043 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2102
Query: 164 QAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQ 223
+A Q R EE R +Q +EQ A +A +L ++++ E Q
Sbjct: 2103 EA--------AQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQ 2154
Query: 224 PALRPNPTA 232
ALR A
Sbjct: 2155 AALRQKQAA 2163
Score = 35.8 bits (81), Expect = 0.053
Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 6/104 (5%)
Query: 109 QAEKLLEEEEKRVQK--EREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAH 166
Q E+LL+E + Q +D L + + + K +L + + Q+L++ QRQ
Sbjct: 2480 QQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQ 2539
Query: 167 VDFEAMLRQHRLSEEERRRQQQEED----EQETAALLEEARKRR 206
+ R EE RRRQ + E+ +QE LE+ R+++
Sbjct: 2540 QMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2583
Score = 33.5 bits (75), Expect = 0.26
Identities = 30/121 (24%), Positives = 55/121 (45%), Gaps = 8/121 (6%)
Query: 109 QAEKLLEEEEKRVQ-KEREDEELNNPMKVLENRTKDSKLEMEVLENLQ-----ELKDLNQ 162
+ ++L + E +Q K R+ E +E + +L++E E + EL+ L
Sbjct: 1421 ELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRA 1480
Query: 163 RQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPL 222
R EA RQ + E RRQ Q+E +++ A +E A + + ++ E + A L
Sbjct: 1481 RAEEA--EAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQAL 1538
Query: 223 Q 223
+
Sbjct: 1539 E 1539
Score = 33.5 bits (75), Expect = 0.26
Identities = 31/125 (24%), Positives = 54/125 (43%), Gaps = 10/125 (8%)
Query: 104 ATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDS---KLEM------EVLENL 154
A + Q E+ L+EE V + RE+ E + R ++ +LE E L
Sbjct: 1586 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1645
Query: 155 QELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLE-EARKRRLLEDSDS 213
+ +++ Q+++ EA ++ E RRR + EE L E E K+R L + +
Sbjct: 1646 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1705
Query: 214 EDEAA 218
+ A
Sbjct: 1706 QQRLA 1710
Score = 33.1 bits (74), Expect = 0.34
Identities = 33/135 (24%), Positives = 64/135 (47%), Gaps = 12/135 (8%)
Query: 117 EEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLE-NLQELKDLNQRQAHVDFEAMLRQ 175
E +R Q + + E L + LE + + E ++L+ +E++ + Q Q + +A L+Q
Sbjct: 2435 EIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQA-LQQ 2493
Query: 176 HRLSEEERRRQQQEEDEQETAALL-----EEARKRRLLEDSDSEDEAAPSPLQPALRPNP 230
LSE++ Q++ EQE A L E A+ ++L E+ + + R
Sbjct: 2494 SFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE-----RQRL 2548
Query: 231 TAILDEAPKPKRKVE 245
A ++EA + + + E
Sbjct: 2549 VASMEEARRRQHEAE 2563
Score = 32.3 bits (72), Expect = 0.58
Identities = 29/119 (24%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Query: 101 EHGATRNFQAEKLLEEEEKRVQKE--REDEELNNPMKVLENRTKDSKLEMEVLENLQELK 158
E A + +AE+ EE E+ +++ + +E L ++ E + S + E + +E +
Sbjct: 1611 ERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAE 1670
Query: 159 DLNQRQAHVDFEAMLRQHRLSEEERRRQQQEED---EQETAALLEEARKRRLLEDSDSE 214
+R+ + +A+ RQ L+E+E +Q+Q + +Q AA E R R E + +
Sbjct: 1671 REARRRGKAEEQAV-RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1728
Score = 31.6 bits (70), Expect = 1.00
Identities = 37/152 (24%), Positives = 60/152 (39%), Gaps = 15/152 (9%)
Query: 104 ATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQR 163
A Q EEE R +K +E KV E R + E E LQ ++ Q+
Sbjct: 1986 AEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQK 2045
Query: 164 QAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSD-----SEDEAA 218
+ + +A + E+E ++ Q+E E RR E+++ +E EAA
Sbjct: 2046 RLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAA 2105
Query: 219 PSPLQPALRPNPTAILDEAPKPKRKVEVWEQS 250
S Q ++EA + K+ E Q+
Sbjct: 2106 QSRRQ----------VEEAERLKQSAEEQAQA 2127
Score = 31.2 bits (69), Expect = 1.3
Identities = 23/114 (20%), Positives = 52/114 (45%), Gaps = 19/114 (16%)
Query: 114 LEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAML 173
+EEEE+ +++R +E E L ++ + ++ A +A
Sbjct: 1344 MEEEERLAEQQRAEER-------------------ERLAEVEAALEKQRQLAEAHAQAKA 1384
Query: 174 RQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQPALR 227
+ R ++E ++R Q+E +E AA+ + +KR + E+ +++ + +Q R
Sbjct: 1385 QAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKAR 1438
Score = 31.2 bits (69), Expect = 1.3
Identities = 35/135 (25%), Positives = 59/135 (43%), Gaps = 26/135 (19%)
Query: 109 QAEKLLEEE------------EKRVQKEREDEELNNPMKVL---------ENRTKDSKLE 147
Q +LLEEE +KR + E E ++ M+VL E+R+ K +
Sbjct: 1727 QQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSK 1786
Query: 148 MEVLENLQELKDLNQRQAHVDF--EAMLRQHRLSEEERRRQQQEEDE---QETAALLEEA 202
+ ++L + A + E RQ +L+EE+ RQ+ E + ++ AA+ E
Sbjct: 1787 QRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEAT 1846
Query: 203 RKRRLLEDSDSEDEA 217
R + E + E EA
Sbjct: 1847 RLKTEAEIALKEKEA 1861
Score = 31.2 bits (69), Expect = 1.3
Identities = 34/141 (24%), Positives = 65/141 (46%), Gaps = 15/141 (10%)
Query: 115 EEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDF----- 169
E EE RVQ ERE + ++ E + ++ + + Q + +++A +
Sbjct: 2092 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2151
Query: 170 --EAMLRQHRL--SEEERRRQQQEEDEQETAALLEEARKRRL-LEDSDSEDEAAPSPLQP 224
+A LRQ + +E E+ ++ E+ ++ A + +E RL LE++D + LQ
Sbjct: 2152 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ- 2210
Query: 225 ALRPNPTAILDEAPKPKRKVE 245
L+ T EA + + +VE
Sbjct: 2211 RLKAEAT----EAARQRSQVE 2227
Score = 30.8 bits (68), Expect = 1.7
Identities = 35/137 (25%), Positives = 63/137 (45%), Gaps = 30/137 (21%)
Query: 109 QAEKLLEEEEKRVQK----EREDEELNNPMKVLENRTKDSKLEMEVLEN----------- 153
Q + LLEE E+ +K +R ++ N +K E + K ++E + +
Sbjct: 1250 QEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGS 1309
Query: 154 ---LQELKDLNQRQAHVDFEAMLRQH---------RLSEEERRRQQQEEDEQETAALLEE 201
+QE DL R + + + Q+ R+ EEER +QQ +E+E A +E
Sbjct: 1310 ESVIQEYVDL--RTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEA 1367
Query: 202 A-RKRRLLEDSDSEDEA 217
A K+R L ++ ++ +A
Sbjct: 1368 ALEKQRQLAEAHAQAKA 1384
Score = 30.8 bits (68), Expect = 1.7
Identities = 44/214 (20%), Positives = 81/214 (37%), Gaps = 31/214 (14%)
Query: 90 KTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEME 149
+++ E+T + E + +L EEE+R + +E + + E + K +E
Sbjct: 1952 RSNAEDTLRSKEQAELEAARQRQLAAEEERR--RREAEERVQKSLAAEEEAARQRKAALE 2009
Query: 150 VLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLE 209
+E L+ ++ E R R++ E++ L +EA ++RL
Sbjct: 2010 EVERLKA--------------------KVEEARRLRERAEQESARQLQLAQEAAQKRLQA 2049
Query: 210 DSDSEDEAA---PSPLQPALRPNPTAILD----EAPKPKRKVEVWEQSVGSLGSRPPLSR 262
+ + A LQ L+ ++LD EA +R E E++ SR
Sbjct: 2050 EEKAHAFAVQQKEQELQQTLQ-QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR 2108
Query: 263 LVVVKKAKADPDC-SNGQPQAAPTPGAPQNRKEA 295
V + + Q +A A + RKEA
Sbjct: 2109 RQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2142
Score = 30.8 bits (68), Expect = 1.7
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 13/108 (12%)
Query: 110 AEKLLEEEEKRV------------QKEREDEELNNPMKVLENRTKD-SKLEMEVLENLQE 156
AEKL +E E+ QK+ D E+ K E + +++E E+ +
Sbjct: 2135 AEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2194
Query: 157 LKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARK 204
L++ + ++ +D E + +E R+R Q EE+ +EE K
Sbjct: 2195 LEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSK 2242
Score = 30.4 bits (67), Expect = 2.2
Identities = 31/105 (29%), Positives = 50/105 (47%), Gaps = 13/105 (12%)
Query: 110 AEKLLEEEEKRVQKE---REDEELNNPMKVLEN----RTKDSKLEM--EVLENLQ----E 156
AEK+L+E+ + VQ+ + + EL K L R ++ K +M ++ E Q
Sbjct: 2308 AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT 2367
Query: 157 LKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEE 201
L+ QRQ + EA + R++E R + + EED Q EE
Sbjct: 2368 LEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEE 2412
Score = 29.6 bits (65), Expect = 3.8
Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 6/93 (6%)
Query: 113 LLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAM 172
L EE EK Q E L+ + + ++L E+L + + L ++ +A+
Sbjct: 2266 LQEEAEKMKQVAEEAARLSVAAQ------EAARLRQLAEEDLAQQRALAEKMLKEKMQAV 2319
Query: 173 LRQHRLSEEERRRQQQEEDEQETAALLEEARKR 205
RL E QQQ+E QE A L+E +++
Sbjct: 2320 QEATRLKAEAELLQQQKELAQEQARRLQEDKEQ 2352
Score = 29.3 bits (64), Expect = 4.9
Identities = 26/111 (23%), Positives = 50/111 (45%), Gaps = 3/111 (2%)
Query: 116 EEEKRVQKEREDEELNNPMKVLENRTKDS-KLEMEVLENLQELKDLNQRQAHVDFEAMLR 174
EE+ Q+E ++EL ++ E + E E++ E + Q++ ++ E
Sbjct: 1680 EEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1739
Query: 175 QHRLSEEERRRQQQEEDEQETAALLEE--ARKRRLLEDSDSEDEAAPSPLQ 223
Q + ++RQ+ E + + A +E A K R E+S S E + L+
Sbjct: 1740 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLE 1790
Score = 28.5 bits (62), Expect = 8.4
Identities = 27/110 (24%), Positives = 52/110 (47%), Gaps = 9/110 (8%)
Query: 112 KLLEEEEKRVQK----EREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHV 167
+L EE E+R Q+ ER EE ++ + + ++ E + + K L Q +A
Sbjct: 1605 QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK 1664
Query: 168 DFEAMLRQHRL---SEEERRRQQQ--EEDEQETAALLEEARKRRLLEDSD 212
E R+ R +EE+ RQ++ E++ ++ L E ++RL + +
Sbjct: 1665 QKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQE 1714
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 43.9 bits (102), Expect = 2e-04
Identities = 30/117 (25%), Positives = 57/117 (48%)
Query: 90 KTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEME 149
K D E + + + +K L E+ R +++ E+E L + ++LE+E
Sbjct: 1856 KADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELE 1915
Query: 150 VLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRR 206
+ +D + + + EA ++ +EEERRR++ EE Q++ A EEA ++R
Sbjct: 1916 LGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 1972
Score = 40.4 bits (93), Expect = 0.002
Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 10/134 (7%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD 168
Q E+ +E+E+ ++++ +DE E + + ++E E + +++ +RQ +
Sbjct: 2472 QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE 2531
Query: 169 FEAMLRQHRLSEEERRRQQQEE---DE----QETAALLEEARKRRLLEDSDSEDEAAPSP 221
+Q L + E++R+QQEE +E +E LLEE + L + SE+ A
Sbjct: 2532 EGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL---AHSEEVTASQV 2588
Query: 222 LQPALRPNPTAILD 235
PN LD
Sbjct: 2589 AATKTLPNGRDALD 2602
Score = 37.4 bits (85), Expect = 0.018
Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 14/129 (10%)
Query: 110 AEKLLEEEEKR-----VQKERE-DEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQR 163
A+K L+ EEK QKE+E + L VL+ +++ E +E + +R
Sbjct: 2011 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2070
Query: 164 QAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQ 223
+A Q R EE R +Q +EQ A +A +L ++++ E Q
Sbjct: 2071 EA--------AQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQ 2122
Query: 224 PALRPNPTA 232
ALR A
Sbjct: 2123 AALRQKQAA 2131
Score = 35.8 bits (81), Expect = 0.053
Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 6/104 (5%)
Query: 109 QAEKLLEEEEKRVQK--EREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAH 166
Q E+LL+E + Q +D L + + + K +L + + Q+L++ QRQ
Sbjct: 2448 QQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQ 2507
Query: 167 VDFEAMLRQHRLSEEERRRQQQEED----EQETAALLEEARKRR 206
+ R EE RRRQ + E+ +QE LE+ R+++
Sbjct: 2508 QMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2551
Score = 33.5 bits (75), Expect = 0.26
Identities = 30/121 (24%), Positives = 55/121 (45%), Gaps = 8/121 (6%)
Query: 109 QAEKLLEEEEKRVQ-KEREDEELNNPMKVLENRTKDSKLEMEVLENLQ-----ELKDLNQ 162
+ ++L + E +Q K R+ E +E + +L++E E + EL+ L
Sbjct: 1389 ELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRA 1448
Query: 163 RQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPL 222
R EA RQ + E RRQ Q+E +++ A +E A + + ++ E + A L
Sbjct: 1449 RAEEA--EAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQAL 1506
Query: 223 Q 223
+
Sbjct: 1507 E 1507
Score = 33.5 bits (75), Expect = 0.26
Identities = 31/125 (24%), Positives = 54/125 (43%), Gaps = 10/125 (8%)
Query: 104 ATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDS---KLEM------EVLENL 154
A + Q E+ L+EE V + RE+ E + R ++ +LE E L
Sbjct: 1554 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1613
Query: 155 QELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLE-EARKRRLLEDSDS 213
+ +++ Q+++ EA ++ E RRR + EE L E E K+R L + +
Sbjct: 1614 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1673
Query: 214 EDEAA 218
+ A
Sbjct: 1674 QQRLA 1678
Score = 33.1 bits (74), Expect = 0.34
Identities = 33/135 (24%), Positives = 64/135 (47%), Gaps = 12/135 (8%)
Query: 117 EEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLE-NLQELKDLNQRQAHVDFEAMLRQ 175
E +R Q + + E L + LE + + E ++L+ +E++ + Q Q + +A L+Q
Sbjct: 2403 EIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQA-LQQ 2461
Query: 176 HRLSEEERRRQQQEEDEQETAALL-----EEARKRRLLEDSDSEDEAAPSPLQPALRPNP 230
LSE++ Q++ EQE A L E A+ ++L E+ + + R
Sbjct: 2462 SFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE-----RQRL 2516
Query: 231 TAILDEAPKPKRKVE 245
A ++EA + + + E
Sbjct: 2517 VASMEEARRRQHEAE 2531
Score = 32.3 bits (72), Expect = 0.58
Identities = 29/119 (24%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Query: 101 EHGATRNFQAEKLLEEEEKRVQKE--REDEELNNPMKVLENRTKDSKLEMEVLENLQELK 158
E A + +AE+ EE E+ +++ + +E L ++ E + S + E + +E +
Sbjct: 1579 ERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAE 1638
Query: 159 DLNQRQAHVDFEAMLRQHRLSEEERRRQQQEED---EQETAALLEEARKRRLLEDSDSE 214
+R+ + +A+ RQ L+E+E +Q+Q + +Q AA E R R E + +
Sbjct: 1639 REARRRGKAEEQAV-RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1696
Score = 31.6 bits (70), Expect = 1.00
Identities = 37/152 (24%), Positives = 60/152 (39%), Gaps = 15/152 (9%)
Query: 104 ATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQR 163
A Q EEE R +K +E KV E R + E E LQ ++ Q+
Sbjct: 1954 AEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQK 2013
Query: 164 QAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSD-----SEDEAA 218
+ + +A + E+E ++ Q+E E RR E+++ +E EAA
Sbjct: 2014 RLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAA 2073
Query: 219 PSPLQPALRPNPTAILDEAPKPKRKVEVWEQS 250
S Q ++EA + K+ E Q+
Sbjct: 2074 QSRRQ----------VEEAERLKQSAEEQAQA 2095
Score = 31.2 bits (69), Expect = 1.3
Identities = 23/114 (20%), Positives = 52/114 (45%), Gaps = 19/114 (16%)
Query: 114 LEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAML 173
+EEEE+ +++R +E E L ++ + ++ A +A
Sbjct: 1312 MEEEERLAEQQRAEER-------------------ERLAEVEAALEKQRQLAEAHAQAKA 1352
Query: 174 RQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQPALR 227
+ R ++E ++R Q+E +E AA+ + +KR + E+ +++ + +Q R
Sbjct: 1353 QAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKAR 1406
Score = 31.2 bits (69), Expect = 1.3
Identities = 35/135 (25%), Positives = 59/135 (43%), Gaps = 26/135 (19%)
Query: 109 QAEKLLEEE------------EKRVQKEREDEELNNPMKVL---------ENRTKDSKLE 147
Q +LLEEE +KR + E E ++ M+VL E+R+ K +
Sbjct: 1695 QQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSK 1754
Query: 148 MEVLENLQELKDLNQRQAHVDF--EAMLRQHRLSEEERRRQQQEEDE---QETAALLEEA 202
+ ++L + A + E RQ +L+EE+ RQ+ E + ++ AA+ E
Sbjct: 1755 QRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEAT 1814
Query: 203 RKRRLLEDSDSEDEA 217
R + E + E EA
Sbjct: 1815 RLKTEAEIALKEKEA 1829
Score = 31.2 bits (69), Expect = 1.3
Identities = 34/141 (24%), Positives = 65/141 (46%), Gaps = 15/141 (10%)
Query: 115 EEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDF----- 169
E EE RVQ ERE + ++ E + ++ + + Q + +++A +
Sbjct: 2060 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2119
Query: 170 --EAMLRQHRL--SEEERRRQQQEEDEQETAALLEEARKRRL-LEDSDSEDEAAPSPLQP 224
+A LRQ + +E E+ ++ E+ ++ A + +E RL LE++D + LQ
Sbjct: 2120 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ- 2178
Query: 225 ALRPNPTAILDEAPKPKRKVE 245
L+ T EA + + +VE
Sbjct: 2179 RLKAEAT----EAARQRSQVE 2195
Score = 30.8 bits (68), Expect = 1.7
Identities = 35/137 (25%), Positives = 63/137 (45%), Gaps = 30/137 (21%)
Query: 109 QAEKLLEEEEKRVQK----EREDEELNNPMKVLENRTKDSKLEMEVLEN----------- 153
Q + LLEE E+ +K +R ++ N +K E + K ++E + +
Sbjct: 1218 QEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGS 1277
Query: 154 ---LQELKDLNQRQAHVDFEAMLRQH---------RLSEEERRRQQQEEDEQETAALLEE 201
+QE DL R + + + Q+ R+ EEER +QQ +E+E A +E
Sbjct: 1278 ESVIQEYVDL--RTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEA 1335
Query: 202 A-RKRRLLEDSDSEDEA 217
A K+R L ++ ++ +A
Sbjct: 1336 ALEKQRQLAEAHAQAKA 1352
Score = 30.8 bits (68), Expect = 1.7
Identities = 44/214 (20%), Positives = 81/214 (37%), Gaps = 31/214 (14%)
Query: 90 KTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEME 149
+++ E+T + E + +L EEE+R + +E + + E + K +E
Sbjct: 1920 RSNAEDTLRSKEQAELEAARQRQLAAEEERR--RREAEERVQKSLAAEEEAARQRKAALE 1977
Query: 150 VLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLE 209
+E L+ ++ E R R++ E++ L +EA ++RL
Sbjct: 1978 EVERLKA--------------------KVEEARRLRERAEQESARQLQLAQEAAQKRLQA 2017
Query: 210 DSDSEDEAA---PSPLQPALRPNPTAILD----EAPKPKRKVEVWEQSVGSLGSRPPLSR 262
+ + A LQ L+ ++LD EA +R E E++ SR
Sbjct: 2018 EEKAHAFAVQQKEQELQQTLQ-QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR 2076
Query: 263 LVVVKKAKADPDC-SNGQPQAAPTPGAPQNRKEA 295
V + + Q +A A + RKEA
Sbjct: 2077 RQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2110
Score = 30.8 bits (68), Expect = 1.7
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 13/108 (12%)
Query: 110 AEKLLEEEEKRV------------QKEREDEELNNPMKVLENRTKD-SKLEMEVLENLQE 156
AEKL +E E+ QK+ D E+ K E + +++E E+ +
Sbjct: 2103 AEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2162
Query: 157 LKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARK 204
L++ + ++ +D E + +E R+R Q EE+ +EE K
Sbjct: 2163 LEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSK 2210
Score = 30.4 bits (67), Expect = 2.2
Identities = 31/105 (29%), Positives = 50/105 (47%), Gaps = 13/105 (12%)
Query: 110 AEKLLEEEEKRVQKE---REDEELNNPMKVLEN----RTKDSKLEM--EVLENLQ----E 156
AEK+L+E+ + VQ+ + + EL K L R ++ K +M ++ E Q
Sbjct: 2276 AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT 2335
Query: 157 LKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEE 201
L+ QRQ + EA + R++E R + + EED Q EE
Sbjct: 2336 LEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEE 2380
Score = 29.6 bits (65), Expect = 3.8
Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 6/93 (6%)
Query: 113 LLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAM 172
L EE EK Q E L+ + + ++L E+L + + L ++ +A+
Sbjct: 2234 LQEEAEKMKQVAEEAARLSVAAQ------EAARLRQLAEEDLAQQRALAEKMLKEKMQAV 2287
Query: 173 LRQHRLSEEERRRQQQEEDEQETAALLEEARKR 205
RL E QQQ+E QE A L+E +++
Sbjct: 2288 QEATRLKAEAELLQQQKELAQEQARRLQEDKEQ 2320
Score = 29.3 bits (64), Expect = 4.9
Identities = 26/111 (23%), Positives = 50/111 (45%), Gaps = 3/111 (2%)
Query: 116 EEEKRVQKEREDEELNNPMKVLENRTKDS-KLEMEVLENLQELKDLNQRQAHVDFEAMLR 174
EE+ Q+E ++EL ++ E + E E++ E + Q++ ++ E
Sbjct: 1648 EEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1707
Query: 175 QHRLSEEERRRQQQEEDEQETAALLEE--ARKRRLLEDSDSEDEAAPSPLQ 223
Q + ++RQ+ E + + A +E A K R E+S S E + L+
Sbjct: 1708 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLE 1758
Score = 28.5 bits (62), Expect = 8.4
Identities = 27/110 (24%), Positives = 52/110 (47%), Gaps = 9/110 (8%)
Query: 112 KLLEEEEKRVQK----EREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHV 167
+L EE E+R Q+ ER EE ++ + + ++ E + + K L Q +A
Sbjct: 1573 QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK 1632
Query: 168 DFEAMLRQHRL---SEEERRRQQQ--EEDEQETAALLEEARKRRLLEDSD 212
E R+ R +EE+ RQ++ E++ ++ L E ++RL + +
Sbjct: 1633 QKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQE 1682
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 43.9 bits (102), Expect = 2e-04
Identities = 30/117 (25%), Positives = 57/117 (48%)
Query: 90 KTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEME 149
K D E + + + +K L E+ R +++ E+E L + ++LE+E
Sbjct: 2025 KADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELE 2084
Query: 150 VLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRR 206
+ +D + + + EA ++ +EEERRR++ EE Q++ A EEA ++R
Sbjct: 2085 LGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2141
Score = 40.4 bits (93), Expect = 0.002
Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 10/134 (7%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD 168
Q E+ +E+E+ ++++ +DE E + + ++E E + +++ +RQ +
Sbjct: 2641 QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE 2700
Query: 169 FEAMLRQHRLSEEERRRQQQEE---DE----QETAALLEEARKRRLLEDSDSEDEAAPSP 221
+Q L + E++R+QQEE +E +E LLEE + L + SE+ A
Sbjct: 2701 EGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL---AHSEEVTASQV 2757
Query: 222 LQPALRPNPTAILD 235
PN LD
Sbjct: 2758 AATKTLPNGRDALD 2771
Score = 37.4 bits (85), Expect = 0.018
Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 14/129 (10%)
Query: 110 AEKLLEEEEKR-----VQKERE-DEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQR 163
A+K L+ EEK QKE+E + L VL+ +++ E +E + +R
Sbjct: 2180 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2239
Query: 164 QAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQ 223
+A Q R EE R +Q +EQ A +A +L ++++ E Q
Sbjct: 2240 EA--------AQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQ 2291
Query: 224 PALRPNPTA 232
ALR A
Sbjct: 2292 AALRQKQAA 2300
Score = 35.8 bits (81), Expect = 0.053
Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 6/104 (5%)
Query: 109 QAEKLLEEEEKRVQK--EREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAH 166
Q E+LL+E + Q +D L + + + K +L + + Q+L++ QRQ
Sbjct: 2617 QQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQ 2676
Query: 167 VDFEAMLRQHRLSEEERRRQQQEED----EQETAALLEEARKRR 206
+ R EE RRRQ + E+ +QE LE+ R+++
Sbjct: 2677 QMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2720
Score = 33.5 bits (75), Expect = 0.26
Identities = 30/121 (24%), Positives = 55/121 (45%), Gaps = 8/121 (6%)
Query: 109 QAEKLLEEEEKRVQ-KEREDEELNNPMKVLENRTKDSKLEMEVLENLQ-----ELKDLNQ 162
+ ++L + E +Q K R+ E +E + +L++E E + EL+ L
Sbjct: 1558 ELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRA 1617
Query: 163 RQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPL 222
R EA RQ + E RRQ Q+E +++ A +E A + + ++ E + A L
Sbjct: 1618 RAEEA--EAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQAL 1675
Query: 223 Q 223
+
Sbjct: 1676 E 1676
Score = 33.5 bits (75), Expect = 0.26
Identities = 31/125 (24%), Positives = 54/125 (43%), Gaps = 10/125 (8%)
Query: 104 ATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDS---KLEM------EVLENL 154
A + Q E+ L+EE V + RE+ E + R ++ +LE E L
Sbjct: 1723 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1782
Query: 155 QELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLE-EARKRRLLEDSDS 213
+ +++ Q+++ EA ++ E RRR + EE L E E K+R L + +
Sbjct: 1783 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1842
Query: 214 EDEAA 218
+ A
Sbjct: 1843 QQRLA 1847
Score = 33.1 bits (74), Expect = 0.34
Identities = 33/135 (24%), Positives = 64/135 (47%), Gaps = 12/135 (8%)
Query: 117 EEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLE-NLQELKDLNQRQAHVDFEAMLRQ 175
E +R Q + + E L + LE + + E ++L+ +E++ + Q Q + +A L+Q
Sbjct: 2572 EIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQA-LQQ 2630
Query: 176 HRLSEEERRRQQQEEDEQETAALL-----EEARKRRLLEDSDSEDEAAPSPLQPALRPNP 230
LSE++ Q++ EQE A L E A+ ++L E+ + + R
Sbjct: 2631 SFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE-----RQRL 2685
Query: 231 TAILDEAPKPKRKVE 245
A ++EA + + + E
Sbjct: 2686 VASMEEARRRQHEAE 2700
Score = 32.3 bits (72), Expect = 0.58
Identities = 29/119 (24%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Query: 101 EHGATRNFQAEKLLEEEEKRVQKE--REDEELNNPMKVLENRTKDSKLEMEVLENLQELK 158
E A + +AE+ EE E+ +++ + +E L ++ E + S + E + +E +
Sbjct: 1748 ERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAE 1807
Query: 159 DLNQRQAHVDFEAMLRQHRLSEEERRRQQQEED---EQETAALLEEARKRRLLEDSDSE 214
+R+ + +A+ RQ L+E+E +Q+Q + +Q AA E R R E + +
Sbjct: 1808 REARRRGKAEEQAV-RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1865
Score = 31.6 bits (70), Expect = 1.00
Identities = 37/152 (24%), Positives = 60/152 (39%), Gaps = 15/152 (9%)
Query: 104 ATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQR 163
A Q EEE R +K +E KV E R + E E LQ ++ Q+
Sbjct: 2123 AEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQK 2182
Query: 164 QAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSD-----SEDEAA 218
+ + +A + E+E ++ Q+E E RR E+++ +E EAA
Sbjct: 2183 RLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAA 2242
Query: 219 PSPLQPALRPNPTAILDEAPKPKRKVEVWEQS 250
S Q ++EA + K+ E Q+
Sbjct: 2243 QSRRQ----------VEEAERLKQSAEEQAQA 2264
Score = 31.2 bits (69), Expect = 1.3
Identities = 23/114 (20%), Positives = 52/114 (45%), Gaps = 19/114 (16%)
Query: 114 LEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAML 173
+EEEE+ +++R +E E L ++ + ++ A +A
Sbjct: 1481 MEEEERLAEQQRAEER-------------------ERLAEVEAALEKQRQLAEAHAQAKA 1521
Query: 174 RQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQPALR 227
+ R ++E ++R Q+E +E AA+ + +KR + E+ +++ + +Q R
Sbjct: 1522 QAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKAR 1575
Score = 31.2 bits (69), Expect = 1.3
Identities = 35/135 (25%), Positives = 59/135 (43%), Gaps = 26/135 (19%)
Query: 109 QAEKLLEEE------------EKRVQKEREDEELNNPMKVL---------ENRTKDSKLE 147
Q +LLEEE +KR + E E ++ M+VL E+R+ K +
Sbjct: 1864 QQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSK 1923
Query: 148 MEVLENLQELKDLNQRQAHVDF--EAMLRQHRLSEEERRRQQQEEDE---QETAALLEEA 202
+ ++L + A + E RQ +L+EE+ RQ+ E + ++ AA+ E
Sbjct: 1924 QRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEAT 1983
Query: 203 RKRRLLEDSDSEDEA 217
R + E + E EA
Sbjct: 1984 RLKTEAEIALKEKEA 1998
Score = 31.2 bits (69), Expect = 1.3
Identities = 34/141 (24%), Positives = 65/141 (46%), Gaps = 15/141 (10%)
Query: 115 EEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDF----- 169
E EE RVQ ERE + ++ E + ++ + + Q + +++A +
Sbjct: 2229 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2288
Query: 170 --EAMLRQHRL--SEEERRRQQQEEDEQETAALLEEARKRRL-LEDSDSEDEAAPSPLQP 224
+A LRQ + +E E+ ++ E+ ++ A + +E RL LE++D + LQ
Sbjct: 2289 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ- 2347
Query: 225 ALRPNPTAILDEAPKPKRKVE 245
L+ T EA + + +VE
Sbjct: 2348 RLKAEAT----EAARQRSQVE 2364
Score = 30.8 bits (68), Expect = 1.7
Identities = 35/137 (25%), Positives = 63/137 (45%), Gaps = 30/137 (21%)
Query: 109 QAEKLLEEEEKRVQK----EREDEELNNPMKVLENRTKDSKLEMEVLEN----------- 153
Q + LLEE E+ +K +R ++ N +K E + K ++E + +
Sbjct: 1387 QEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGS 1446
Query: 154 ---LQELKDLNQRQAHVDFEAMLRQH---------RLSEEERRRQQQEEDEQETAALLEE 201
+QE DL R + + + Q+ R+ EEER +QQ +E+E A +E
Sbjct: 1447 ESVIQEYVDL--RTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEA 1504
Query: 202 A-RKRRLLEDSDSEDEA 217
A K+R L ++ ++ +A
Sbjct: 1505 ALEKQRQLAEAHAQAKA 1521
Score = 30.8 bits (68), Expect = 1.7
Identities = 44/214 (20%), Positives = 81/214 (37%), Gaps = 31/214 (14%)
Query: 90 KTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEME 149
+++ E+T + E + +L EEE+R + +E + + E + K +E
Sbjct: 2089 RSNAEDTLRSKEQAELEAARQRQLAAEEERR--RREAEERVQKSLAAEEEAARQRKAALE 2146
Query: 150 VLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLE 209
+E L+ ++ E R R++ E++ L +EA ++RL
Sbjct: 2147 EVERLKA--------------------KVEEARRLRERAEQESARQLQLAQEAAQKRLQA 2186
Query: 210 DSDSEDEAA---PSPLQPALRPNPTAILD----EAPKPKRKVEVWEQSVGSLGSRPPLSR 262
+ + A LQ L+ ++LD EA +R E E++ SR
Sbjct: 2187 EEKAHAFAVQQKEQELQQTLQ-QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR 2245
Query: 263 LVVVKKAKADPDC-SNGQPQAAPTPGAPQNRKEA 295
V + + Q +A A + RKEA
Sbjct: 2246 RQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2279
Score = 30.8 bits (68), Expect = 1.7
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 13/108 (12%)
Query: 110 AEKLLEEEEKRV------------QKEREDEELNNPMKVLENRTKD-SKLEMEVLENLQE 156
AEKL +E E+ QK+ D E+ K E + +++E E+ +
Sbjct: 2272 AEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2331
Query: 157 LKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARK 204
L++ + ++ +D E + +E R+R Q EE+ +EE K
Sbjct: 2332 LEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSK 2379
Score = 30.4 bits (67), Expect = 2.2
Identities = 31/105 (29%), Positives = 50/105 (47%), Gaps = 13/105 (12%)
Query: 110 AEKLLEEEEKRVQKE---REDEELNNPMKVLEN----RTKDSKLEM--EVLENLQ----E 156
AEK+L+E+ + VQ+ + + EL K L R ++ K +M ++ E Q
Sbjct: 2445 AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT 2504
Query: 157 LKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEE 201
L+ QRQ + EA + R++E R + + EED Q EE
Sbjct: 2505 LEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEE 2549
Score = 29.6 bits (65), Expect = 3.8
Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 6/93 (6%)
Query: 113 LLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAM 172
L EE EK Q E L+ + + ++L E+L + + L ++ +A+
Sbjct: 2403 LQEEAEKMKQVAEEAARLSVAAQ------EAARLRQLAEEDLAQQRALAEKMLKEKMQAV 2456
Query: 173 LRQHRLSEEERRRQQQEEDEQETAALLEEARKR 205
RL E QQQ+E QE A L+E +++
Sbjct: 2457 QEATRLKAEAELLQQQKELAQEQARRLQEDKEQ 2489
Score = 29.3 bits (64), Expect = 4.9
Identities = 26/111 (23%), Positives = 50/111 (45%), Gaps = 3/111 (2%)
Query: 116 EEEKRVQKEREDEELNNPMKVLENRTKDS-KLEMEVLENLQELKDLNQRQAHVDFEAMLR 174
EE+ Q+E ++EL ++ E + E E++ E + Q++ ++ E
Sbjct: 1817 EEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1876
Query: 175 QHRLSEEERRRQQQEEDEQETAALLEE--ARKRRLLEDSDSEDEAAPSPLQ 223
Q + ++RQ+ E + + A +E A K R E+S S E + L+
Sbjct: 1877 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLE 1927
Score = 28.5 bits (62), Expect = 8.4
Identities = 27/110 (24%), Positives = 52/110 (47%), Gaps = 9/110 (8%)
Query: 112 KLLEEEEKRVQK----EREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHV 167
+L EE E+R Q+ ER EE ++ + + ++ E + + K L Q +A
Sbjct: 1742 QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK 1801
Query: 168 DFEAMLRQHRL---SEEERRRQQQ--EEDEQETAALLEEARKRRLLEDSD 212
E R+ R +EE+ RQ++ E++ ++ L E ++RL + +
Sbjct: 1802 QKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQE 1851
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 43.9 bits (102), Expect = 2e-04
Identities = 30/117 (25%), Positives = 57/117 (48%)
Query: 90 KTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEME 149
K D E + + + +K L E+ R +++ E+E L + ++LE+E
Sbjct: 1866 KADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELE 1925
Query: 150 VLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRR 206
+ +D + + + EA ++ +EEERRR++ EE Q++ A EEA ++R
Sbjct: 1926 LGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 1982
Score = 40.4 bits (93), Expect = 0.002
Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 10/134 (7%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD 168
Q E+ +E+E+ ++++ +DE E + + ++E E + +++ +RQ +
Sbjct: 2482 QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE 2541
Query: 169 FEAMLRQHRLSEEERRRQQQEE---DE----QETAALLEEARKRRLLEDSDSEDEAAPSP 221
+Q L + E++R+QQEE +E +E LLEE + L + SE+ A
Sbjct: 2542 EGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL---AHSEEVTASQV 2598
Query: 222 LQPALRPNPTAILD 235
PN LD
Sbjct: 2599 AATKTLPNGRDALD 2612
Score = 37.4 bits (85), Expect = 0.018
Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 14/129 (10%)
Query: 110 AEKLLEEEEKR-----VQKERE-DEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQR 163
A+K L+ EEK QKE+E + L VL+ +++ E +E + +R
Sbjct: 2021 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2080
Query: 164 QAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQ 223
+A Q R EE R +Q +EQ A +A +L ++++ E Q
Sbjct: 2081 EA--------AQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQ 2132
Query: 224 PALRPNPTA 232
ALR A
Sbjct: 2133 AALRQKQAA 2141
Score = 35.8 bits (81), Expect = 0.053
Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 6/104 (5%)
Query: 109 QAEKLLEEEEKRVQK--EREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAH 166
Q E+LL+E + Q +D L + + + K +L + + Q+L++ QRQ
Sbjct: 2458 QQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQ 2517
Query: 167 VDFEAMLRQHRLSEEERRRQQQEED----EQETAALLEEARKRR 206
+ R EE RRRQ + E+ +QE LE+ R+++
Sbjct: 2518 QMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2561
Score = 33.5 bits (75), Expect = 0.26
Identities = 30/121 (24%), Positives = 55/121 (45%), Gaps = 8/121 (6%)
Query: 109 QAEKLLEEEEKRVQ-KEREDEELNNPMKVLENRTKDSKLEMEVLENLQ-----ELKDLNQ 162
+ ++L + E +Q K R+ E +E + +L++E E + EL+ L
Sbjct: 1399 ELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRA 1458
Query: 163 RQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPL 222
R EA RQ + E RRQ Q+E +++ A +E A + + ++ E + A L
Sbjct: 1459 RAEEA--EAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQAL 1516
Query: 223 Q 223
+
Sbjct: 1517 E 1517
Score = 33.5 bits (75), Expect = 0.26
Identities = 31/125 (24%), Positives = 54/125 (43%), Gaps = 10/125 (8%)
Query: 104 ATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDS---KLEM------EVLENL 154
A + Q E+ L+EE V + RE+ E + R ++ +LE E L
Sbjct: 1564 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1623
Query: 155 QELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLE-EARKRRLLEDSDS 213
+ +++ Q+++ EA ++ E RRR + EE L E E K+R L + +
Sbjct: 1624 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1683
Query: 214 EDEAA 218
+ A
Sbjct: 1684 QQRLA 1688
Score = 33.1 bits (74), Expect = 0.34
Identities = 33/135 (24%), Positives = 64/135 (47%), Gaps = 12/135 (8%)
Query: 117 EEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLE-NLQELKDLNQRQAHVDFEAMLRQ 175
E +R Q + + E L + LE + + E ++L+ +E++ + Q Q + +A L+Q
Sbjct: 2413 EIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQA-LQQ 2471
Query: 176 HRLSEEERRRQQQEEDEQETAALL-----EEARKRRLLEDSDSEDEAAPSPLQPALRPNP 230
LSE++ Q++ EQE A L E A+ ++L E+ + + R
Sbjct: 2472 SFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE-----RQRL 2526
Query: 231 TAILDEAPKPKRKVE 245
A ++EA + + + E
Sbjct: 2527 VASMEEARRRQHEAE 2541
Score = 32.3 bits (72), Expect = 0.58
Identities = 29/119 (24%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Query: 101 EHGATRNFQAEKLLEEEEKRVQKE--REDEELNNPMKVLENRTKDSKLEMEVLENLQELK 158
E A + +AE+ EE E+ +++ + +E L ++ E + S + E + +E +
Sbjct: 1589 ERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAE 1648
Query: 159 DLNQRQAHVDFEAMLRQHRLSEEERRRQQQEED---EQETAALLEEARKRRLLEDSDSE 214
+R+ + +A+ RQ L+E+E +Q+Q + +Q AA E R R E + +
Sbjct: 1649 REARRRGKAEEQAV-RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1706
Score = 31.6 bits (70), Expect = 1.00
Identities = 37/152 (24%), Positives = 60/152 (39%), Gaps = 15/152 (9%)
Query: 104 ATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQR 163
A Q EEE R +K +E KV E R + E E LQ ++ Q+
Sbjct: 1964 AEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQK 2023
Query: 164 QAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSD-----SEDEAA 218
+ + +A + E+E ++ Q+E E RR E+++ +E EAA
Sbjct: 2024 RLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAA 2083
Query: 219 PSPLQPALRPNPTAILDEAPKPKRKVEVWEQS 250
S Q ++EA + K+ E Q+
Sbjct: 2084 QSRRQ----------VEEAERLKQSAEEQAQA 2105
Score = 31.2 bits (69), Expect = 1.3
Identities = 23/114 (20%), Positives = 52/114 (45%), Gaps = 19/114 (16%)
Query: 114 LEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAML 173
+EEEE+ +++R +E E L ++ + ++ A +A
Sbjct: 1322 MEEEERLAEQQRAEER-------------------ERLAEVEAALEKQRQLAEAHAQAKA 1362
Query: 174 RQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQPALR 227
+ R ++E ++R Q+E +E AA+ + +KR + E+ +++ + +Q R
Sbjct: 1363 QAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKAR 1416
Score = 31.2 bits (69), Expect = 1.3
Identities = 35/135 (25%), Positives = 59/135 (43%), Gaps = 26/135 (19%)
Query: 109 QAEKLLEEE------------EKRVQKEREDEELNNPMKVL---------ENRTKDSKLE 147
Q +LLEEE +KR + E E ++ M+VL E+R+ K +
Sbjct: 1705 QQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSK 1764
Query: 148 MEVLENLQELKDLNQRQAHVDF--EAMLRQHRLSEEERRRQQQEEDE---QETAALLEEA 202
+ ++L + A + E RQ +L+EE+ RQ+ E + ++ AA+ E
Sbjct: 1765 QRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEAT 1824
Query: 203 RKRRLLEDSDSEDEA 217
R + E + E EA
Sbjct: 1825 RLKTEAEIALKEKEA 1839
Score = 31.2 bits (69), Expect = 1.3
Identities = 34/141 (24%), Positives = 65/141 (46%), Gaps = 15/141 (10%)
Query: 115 EEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDF----- 169
E EE RVQ ERE + ++ E + ++ + + Q + +++A +
Sbjct: 2070 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2129
Query: 170 --EAMLRQHRL--SEEERRRQQQEEDEQETAALLEEARKRRL-LEDSDSEDEAAPSPLQP 224
+A LRQ + +E E+ ++ E+ ++ A + +E RL LE++D + LQ
Sbjct: 2130 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ- 2188
Query: 225 ALRPNPTAILDEAPKPKRKVE 245
L+ T EA + + +VE
Sbjct: 2189 RLKAEAT----EAARQRSQVE 2205
Score = 30.8 bits (68), Expect = 1.7
Identities = 35/137 (25%), Positives = 63/137 (45%), Gaps = 30/137 (21%)
Query: 109 QAEKLLEEEEKRVQK----EREDEELNNPMKVLENRTKDSKLEMEVLEN----------- 153
Q + LLEE E+ +K +R ++ N +K E + K ++E + +
Sbjct: 1228 QEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGS 1287
Query: 154 ---LQELKDLNQRQAHVDFEAMLRQH---------RLSEEERRRQQQEEDEQETAALLEE 201
+QE DL R + + + Q+ R+ EEER +QQ +E+E A +E
Sbjct: 1288 ESVIQEYVDL--RTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEA 1345
Query: 202 A-RKRRLLEDSDSEDEA 217
A K+R L ++ ++ +A
Sbjct: 1346 ALEKQRQLAEAHAQAKA 1362
Score = 30.8 bits (68), Expect = 1.7
Identities = 44/214 (20%), Positives = 81/214 (37%), Gaps = 31/214 (14%)
Query: 90 KTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEME 149
+++ E+T + E + +L EEE+R + +E + + E + K +E
Sbjct: 1930 RSNAEDTLRSKEQAELEAARQRQLAAEEERR--RREAEERVQKSLAAEEEAARQRKAALE 1987
Query: 150 VLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLE 209
+E L+ ++ E R R++ E++ L +EA ++RL
Sbjct: 1988 EVERLKA--------------------KVEEARRLRERAEQESARQLQLAQEAAQKRLQA 2027
Query: 210 DSDSEDEAA---PSPLQPALRPNPTAILD----EAPKPKRKVEVWEQSVGSLGSRPPLSR 262
+ + A LQ L+ ++LD EA +R E E++ SR
Sbjct: 2028 EEKAHAFAVQQKEQELQQTLQ-QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR 2086
Query: 263 LVVVKKAKADPDC-SNGQPQAAPTPGAPQNRKEA 295
V + + Q +A A + RKEA
Sbjct: 2087 RQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2120
Score = 30.8 bits (68), Expect = 1.7
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 13/108 (12%)
Query: 110 AEKLLEEEEKRV------------QKEREDEELNNPMKVLENRTKD-SKLEMEVLENLQE 156
AEKL +E E+ QK+ D E+ K E + +++E E+ +
Sbjct: 2113 AEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2172
Query: 157 LKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARK 204
L++ + ++ +D E + +E R+R Q EE+ +EE K
Sbjct: 2173 LEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSK 2220
Score = 30.4 bits (67), Expect = 2.2
Identities = 31/105 (29%), Positives = 50/105 (47%), Gaps = 13/105 (12%)
Query: 110 AEKLLEEEEKRVQKE---REDEELNNPMKVLEN----RTKDSKLEM--EVLENLQ----E 156
AEK+L+E+ + VQ+ + + EL K L R ++ K +M ++ E Q
Sbjct: 2286 AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT 2345
Query: 157 LKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEE 201
L+ QRQ + EA + R++E R + + EED Q EE
Sbjct: 2346 LEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEE 2390
Score = 29.6 bits (65), Expect = 3.8
Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 6/93 (6%)
Query: 113 LLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAM 172
L EE EK Q E L+ + + ++L E+L + + L ++ +A+
Sbjct: 2244 LQEEAEKMKQVAEEAARLSVAAQ------EAARLRQLAEEDLAQQRALAEKMLKEKMQAV 2297
Query: 173 LRQHRLSEEERRRQQQEEDEQETAALLEEARKR 205
RL E QQQ+E QE A L+E +++
Sbjct: 2298 QEATRLKAEAELLQQQKELAQEQARRLQEDKEQ 2330
Score = 29.3 bits (64), Expect = 4.9
Identities = 26/111 (23%), Positives = 50/111 (45%), Gaps = 3/111 (2%)
Query: 116 EEEKRVQKEREDEELNNPMKVLENRTKDS-KLEMEVLENLQELKDLNQRQAHVDFEAMLR 174
EE+ Q+E ++EL ++ E + E E++ E + Q++ ++ E
Sbjct: 1658 EEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1717
Query: 175 QHRLSEEERRRQQQEEDEQETAALLEE--ARKRRLLEDSDSEDEAAPSPLQ 223
Q + ++RQ+ E + + A +E A K R E+S S E + L+
Sbjct: 1718 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLE 1768
Score = 28.5 bits (62), Expect = 8.4
Identities = 27/110 (24%), Positives = 52/110 (47%), Gaps = 9/110 (8%)
Query: 112 KLLEEEEKRVQK----EREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHV 167
+L EE E+R Q+ ER EE ++ + + ++ E + + K L Q +A
Sbjct: 1583 QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK 1642
Query: 168 DFEAMLRQHRL---SEEERRRQQQ--EEDEQETAALLEEARKRRLLEDSD 212
E R+ R +EE+ RQ++ E++ ++ L E ++RL + +
Sbjct: 1643 QKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQE 1692
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 43.9 bits (102), Expect = 2e-04
Identities = 30/117 (25%), Positives = 57/117 (48%)
Query: 90 KTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEME 149
K D E + + + +K L E+ R +++ E+E L + ++LE+E
Sbjct: 1874 KADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELE 1933
Query: 150 VLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRR 206
+ +D + + + EA ++ +EEERRR++ EE Q++ A EEA ++R
Sbjct: 1934 LGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 1990
Score = 40.4 bits (93), Expect = 0.002
Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 10/134 (7%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD 168
Q E+ +E+E+ ++++ +DE E + + ++E E + +++ +RQ +
Sbjct: 2490 QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE 2549
Query: 169 FEAMLRQHRLSEEERRRQQQEE---DE----QETAALLEEARKRRLLEDSDSEDEAAPSP 221
+Q L + E++R+QQEE +E +E LLEE + L + SE+ A
Sbjct: 2550 EGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL---AHSEEVTASQV 2606
Query: 222 LQPALRPNPTAILD 235
PN LD
Sbjct: 2607 AATKTLPNGRDALD 2620
Score = 37.4 bits (85), Expect = 0.018
Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 14/129 (10%)
Query: 110 AEKLLEEEEKR-----VQKERE-DEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQR 163
A+K L+ EEK QKE+E + L VL+ +++ E +E + +R
Sbjct: 2029 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2088
Query: 164 QAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQ 223
+A Q R EE R +Q +EQ A +A +L ++++ E Q
Sbjct: 2089 EA--------AQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQ 2140
Query: 224 PALRPNPTA 232
ALR A
Sbjct: 2141 AALRQKQAA 2149
Score = 35.8 bits (81), Expect = 0.053
Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 6/104 (5%)
Query: 109 QAEKLLEEEEKRVQK--EREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAH 166
Q E+LL+E + Q +D L + + + K +L + + Q+L++ QRQ
Sbjct: 2466 QQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQ 2525
Query: 167 VDFEAMLRQHRLSEEERRRQQQEED----EQETAALLEEARKRR 206
+ R EE RRRQ + E+ +QE LE+ R+++
Sbjct: 2526 QMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2569
Score = 33.5 bits (75), Expect = 0.26
Identities = 30/121 (24%), Positives = 55/121 (45%), Gaps = 8/121 (6%)
Query: 109 QAEKLLEEEEKRVQ-KEREDEELNNPMKVLENRTKDSKLEMEVLENLQ-----ELKDLNQ 162
+ ++L + E +Q K R+ E +E + +L++E E + EL+ L
Sbjct: 1407 ELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRA 1466
Query: 163 RQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPL 222
R EA RQ + E RRQ Q+E +++ A +E A + + ++ E + A L
Sbjct: 1467 RAEEA--EAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQAL 1524
Query: 223 Q 223
+
Sbjct: 1525 E 1525
Score = 33.5 bits (75), Expect = 0.26
Identities = 31/125 (24%), Positives = 54/125 (43%), Gaps = 10/125 (8%)
Query: 104 ATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDS---KLEM------EVLENL 154
A + Q E+ L+EE V + RE+ E + R ++ +LE E L
Sbjct: 1572 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1631
Query: 155 QELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLE-EARKRRLLEDSDS 213
+ +++ Q+++ EA ++ E RRR + EE L E E K+R L + +
Sbjct: 1632 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1691
Query: 214 EDEAA 218
+ A
Sbjct: 1692 QQRLA 1696
Score = 33.1 bits (74), Expect = 0.34
Identities = 33/135 (24%), Positives = 64/135 (47%), Gaps = 12/135 (8%)
Query: 117 EEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLE-NLQELKDLNQRQAHVDFEAMLRQ 175
E +R Q + + E L + LE + + E ++L+ +E++ + Q Q + +A L+Q
Sbjct: 2421 EIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQA-LQQ 2479
Query: 176 HRLSEEERRRQQQEEDEQETAALL-----EEARKRRLLEDSDSEDEAAPSPLQPALRPNP 230
LSE++ Q++ EQE A L E A+ ++L E+ + + R
Sbjct: 2480 SFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE-----RQRL 2534
Query: 231 TAILDEAPKPKRKVE 245
A ++EA + + + E
Sbjct: 2535 VASMEEARRRQHEAE 2549
Score = 32.3 bits (72), Expect = 0.58
Identities = 29/119 (24%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Query: 101 EHGATRNFQAEKLLEEEEKRVQKE--REDEELNNPMKVLENRTKDSKLEMEVLENLQELK 158
E A + +AE+ EE E+ +++ + +E L ++ E + S + E + +E +
Sbjct: 1597 ERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAE 1656
Query: 159 DLNQRQAHVDFEAMLRQHRLSEEERRRQQQEED---EQETAALLEEARKRRLLEDSDSE 214
+R+ + +A+ RQ L+E+E +Q+Q + +Q AA E R R E + +
Sbjct: 1657 REARRRGKAEEQAV-RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1714
Score = 31.6 bits (70), Expect = 1.00
Identities = 37/152 (24%), Positives = 60/152 (39%), Gaps = 15/152 (9%)
Query: 104 ATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQR 163
A Q EEE R +K +E KV E R + E E LQ ++ Q+
Sbjct: 1972 AEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQK 2031
Query: 164 QAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSD-----SEDEAA 218
+ + +A + E+E ++ Q+E E RR E+++ +E EAA
Sbjct: 2032 RLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAA 2091
Query: 219 PSPLQPALRPNPTAILDEAPKPKRKVEVWEQS 250
S Q ++EA + K+ E Q+
Sbjct: 2092 QSRRQ----------VEEAERLKQSAEEQAQA 2113
Score = 31.2 bits (69), Expect = 1.3
Identities = 23/114 (20%), Positives = 52/114 (45%), Gaps = 19/114 (16%)
Query: 114 LEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAML 173
+EEEE+ +++R +E E L ++ + ++ A +A
Sbjct: 1330 MEEEERLAEQQRAEER-------------------ERLAEVEAALEKQRQLAEAHAQAKA 1370
Query: 174 RQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQPALR 227
+ R ++E ++R Q+E +E AA+ + +KR + E+ +++ + +Q R
Sbjct: 1371 QAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKAR 1424
Score = 31.2 bits (69), Expect = 1.3
Identities = 35/135 (25%), Positives = 59/135 (43%), Gaps = 26/135 (19%)
Query: 109 QAEKLLEEE------------EKRVQKEREDEELNNPMKVL---------ENRTKDSKLE 147
Q +LLEEE +KR + E E ++ M+VL E+R+ K +
Sbjct: 1713 QQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSK 1772
Query: 148 MEVLENLQELKDLNQRQAHVDF--EAMLRQHRLSEEERRRQQQEEDE---QETAALLEEA 202
+ ++L + A + E RQ +L+EE+ RQ+ E + ++ AA+ E
Sbjct: 1773 QRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEAT 1832
Query: 203 RKRRLLEDSDSEDEA 217
R + E + E EA
Sbjct: 1833 RLKTEAEIALKEKEA 1847
Score = 31.2 bits (69), Expect = 1.3
Identities = 34/141 (24%), Positives = 65/141 (46%), Gaps = 15/141 (10%)
Query: 115 EEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDF----- 169
E EE RVQ ERE + ++ E + ++ + + Q + +++A +
Sbjct: 2078 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2137
Query: 170 --EAMLRQHRL--SEEERRRQQQEEDEQETAALLEEARKRRL-LEDSDSEDEAAPSPLQP 224
+A LRQ + +E E+ ++ E+ ++ A + +E RL LE++D + LQ
Sbjct: 2138 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ- 2196
Query: 225 ALRPNPTAILDEAPKPKRKVE 245
L+ T EA + + +VE
Sbjct: 2197 RLKAEAT----EAARQRSQVE 2213
Score = 30.8 bits (68), Expect = 1.7
Identities = 35/137 (25%), Positives = 63/137 (45%), Gaps = 30/137 (21%)
Query: 109 QAEKLLEEEEKRVQK----EREDEELNNPMKVLENRTKDSKLEMEVLEN----------- 153
Q + LLEE E+ +K +R ++ N +K E + K ++E + +
Sbjct: 1236 QEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGS 1295
Query: 154 ---LQELKDLNQRQAHVDFEAMLRQH---------RLSEEERRRQQQEEDEQETAALLEE 201
+QE DL R + + + Q+ R+ EEER +QQ +E+E A +E
Sbjct: 1296 ESVIQEYVDL--RTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEA 1353
Query: 202 A-RKRRLLEDSDSEDEA 217
A K+R L ++ ++ +A
Sbjct: 1354 ALEKQRQLAEAHAQAKA 1370
Score = 30.8 bits (68), Expect = 1.7
Identities = 44/214 (20%), Positives = 81/214 (37%), Gaps = 31/214 (14%)
Query: 90 KTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEME 149
+++ E+T + E + +L EEE+R + +E + + E + K +E
Sbjct: 1938 RSNAEDTLRSKEQAELEAARQRQLAAEEERR--RREAEERVQKSLAAEEEAARQRKAALE 1995
Query: 150 VLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLE 209
+E L+ ++ E R R++ E++ L +EA ++RL
Sbjct: 1996 EVERLKA--------------------KVEEARRLRERAEQESARQLQLAQEAAQKRLQA 2035
Query: 210 DSDSEDEAA---PSPLQPALRPNPTAILD----EAPKPKRKVEVWEQSVGSLGSRPPLSR 262
+ + A LQ L+ ++LD EA +R E E++ SR
Sbjct: 2036 EEKAHAFAVQQKEQELQQTLQ-QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR 2094
Query: 263 LVVVKKAKADPDC-SNGQPQAAPTPGAPQNRKEA 295
V + + Q +A A + RKEA
Sbjct: 2095 RQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2128
Score = 30.8 bits (68), Expect = 1.7
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 13/108 (12%)
Query: 110 AEKLLEEEEKRV------------QKEREDEELNNPMKVLENRTKD-SKLEMEVLENLQE 156
AEKL +E E+ QK+ D E+ K E + +++E E+ +
Sbjct: 2121 AEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2180
Query: 157 LKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARK 204
L++ + ++ +D E + +E R+R Q EE+ +EE K
Sbjct: 2181 LEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSK 2228
Score = 30.4 bits (67), Expect = 2.2
Identities = 31/105 (29%), Positives = 50/105 (47%), Gaps = 13/105 (12%)
Query: 110 AEKLLEEEEKRVQKE---REDEELNNPMKVLEN----RTKDSKLEM--EVLENLQ----E 156
AEK+L+E+ + VQ+ + + EL K L R ++ K +M ++ E Q
Sbjct: 2294 AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT 2353
Query: 157 LKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEE 201
L+ QRQ + EA + R++E R + + EED Q EE
Sbjct: 2354 LEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEE 2398
Score = 29.6 bits (65), Expect = 3.8
Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 6/93 (6%)
Query: 113 LLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAM 172
L EE EK Q E L+ + + ++L E+L + + L ++ +A+
Sbjct: 2252 LQEEAEKMKQVAEEAARLSVAAQ------EAARLRQLAEEDLAQQRALAEKMLKEKMQAV 2305
Query: 173 LRQHRLSEEERRRQQQEEDEQETAALLEEARKR 205
RL E QQQ+E QE A L+E +++
Sbjct: 2306 QEATRLKAEAELLQQQKELAQEQARRLQEDKEQ 2338
Score = 29.3 bits (64), Expect = 4.9
Identities = 26/111 (23%), Positives = 50/111 (45%), Gaps = 3/111 (2%)
Query: 116 EEEKRVQKEREDEELNNPMKVLENRTKDS-KLEMEVLENLQELKDLNQRQAHVDFEAMLR 174
EE+ Q+E ++EL ++ E + E E++ E + Q++ ++ E
Sbjct: 1666 EEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1725
Query: 175 QHRLSEEERRRQQQEEDEQETAALLEE--ARKRRLLEDSDSEDEAAPSPLQ 223
Q + ++RQ+ E + + A +E A K R E+S S E + L+
Sbjct: 1726 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLE 1776
Score = 28.5 bits (62), Expect = 8.4
Identities = 27/110 (24%), Positives = 52/110 (47%), Gaps = 9/110 (8%)
Query: 112 KLLEEEEKRVQK----EREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHV 167
+L EE E+R Q+ ER EE ++ + + ++ E + + K L Q +A
Sbjct: 1591 QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK 1650
Query: 168 DFEAMLRQHRL---SEEERRRQQQ--EEDEQETAALLEEARKRRLLEDSD 212
E R+ R +EE+ RQ++ E++ ++ L E ++RL + +
Sbjct: 1651 QKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQE 1700
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 43.9 bits (102), Expect = 2e-04
Identities = 30/117 (25%), Positives = 57/117 (48%)
Query: 90 KTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEME 149
K D E + + + +K L E+ R +++ E+E L + ++LE+E
Sbjct: 1915 KADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELE 1974
Query: 150 VLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRR 206
+ +D + + + EA ++ +EEERRR++ EE Q++ A EEA ++R
Sbjct: 1975 LGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2031
Score = 40.4 bits (93), Expect = 0.002
Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 10/134 (7%)
Query: 109 QAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVD 168
Q E+ +E+E+ ++++ +DE E + + ++E E + +++ +RQ +
Sbjct: 2531 QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE 2590
Query: 169 FEAMLRQHRLSEEERRRQQQEE---DE----QETAALLEEARKRRLLEDSDSEDEAAPSP 221
+Q L + E++R+QQEE +E +E LLEE + L + SE+ A
Sbjct: 2591 EGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL---AHSEEVTASQV 2647
Query: 222 LQPALRPNPTAILD 235
PN LD
Sbjct: 2648 AATKTLPNGRDALD 2661
Score = 37.4 bits (85), Expect = 0.018
Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 14/129 (10%)
Query: 110 AEKLLEEEEKR-----VQKERE-DEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQR 163
A+K L+ EEK QKE+E + L VL+ +++ E +E + +R
Sbjct: 2070 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2129
Query: 164 QAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQ 223
+A Q R EE R +Q +EQ A +A +L ++++ E Q
Sbjct: 2130 EA--------AQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQ 2181
Query: 224 PALRPNPTA 232
ALR A
Sbjct: 2182 AALRQKQAA 2190
Score = 35.8 bits (81), Expect = 0.053
Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 6/104 (5%)
Query: 109 QAEKLLEEEEKRVQK--EREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAH 166
Q E+LL+E + Q +D L + + + K +L + + Q+L++ QRQ
Sbjct: 2507 QQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQ 2566
Query: 167 VDFEAMLRQHRLSEEERRRQQQEED----EQETAALLEEARKRR 206
+ R EE RRRQ + E+ +QE LE+ R+++
Sbjct: 2567 QMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2610
Score = 33.5 bits (75), Expect = 0.26
Identities = 30/121 (24%), Positives = 55/121 (45%), Gaps = 8/121 (6%)
Query: 109 QAEKLLEEEEKRVQ-KEREDEELNNPMKVLENRTKDSKLEMEVLENLQ-----ELKDLNQ 162
+ ++L + E +Q K R+ E +E + +L++E E + EL+ L
Sbjct: 1448 ELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRA 1507
Query: 163 RQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPL 222
R EA RQ + E RRQ Q+E +++ A +E A + + ++ E + A L
Sbjct: 1508 RAEEA--EAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQAL 1565
Query: 223 Q 223
+
Sbjct: 1566 E 1566
Score = 33.5 bits (75), Expect = 0.26
Identities = 31/125 (24%), Positives = 54/125 (43%), Gaps = 10/125 (8%)
Query: 104 ATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDS---KLEM------EVLENL 154
A + Q E+ L+EE V + RE+ E + R ++ +LE E L
Sbjct: 1613 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1672
Query: 155 QELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLE-EARKRRLLEDSDS 213
+ +++ Q+++ EA ++ E RRR + EE L E E K+R L + +
Sbjct: 1673 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1732
Query: 214 EDEAA 218
+ A
Sbjct: 1733 QQRLA 1737
Score = 33.1 bits (74), Expect = 0.34
Identities = 33/135 (24%), Positives = 64/135 (47%), Gaps = 12/135 (8%)
Query: 117 EEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLE-NLQELKDLNQRQAHVDFEAMLRQ 175
E +R Q + + E L + LE + + E ++L+ +E++ + Q Q + +A L+Q
Sbjct: 2462 EIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQA-LQQ 2520
Query: 176 HRLSEEERRRQQQEEDEQETAALL-----EEARKRRLLEDSDSEDEAAPSPLQPALRPNP 230
LSE++ Q++ EQE A L E A+ ++L E+ + + R
Sbjct: 2521 SFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE-----RQRL 2575
Query: 231 TAILDEAPKPKRKVE 245
A ++EA + + + E
Sbjct: 2576 VASMEEARRRQHEAE 2590
Score = 32.3 bits (72), Expect = 0.58
Identities = 29/119 (24%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Query: 101 EHGATRNFQAEKLLEEEEKRVQKE--REDEELNNPMKVLENRTKDSKLEMEVLENLQELK 158
E A + +AE+ EE E+ +++ + +E L ++ E + S + E + +E +
Sbjct: 1638 ERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAE 1697
Query: 159 DLNQRQAHVDFEAMLRQHRLSEEERRRQQQEED---EQETAALLEEARKRRLLEDSDSE 214
+R+ + +A+ RQ L+E+E +Q+Q + +Q AA E R R E + +
Sbjct: 1698 REARRRGKAEEQAV-RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1755
Score = 31.6 bits (70), Expect = 1.00
Identities = 37/152 (24%), Positives = 60/152 (39%), Gaps = 15/152 (9%)
Query: 104 ATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQR 163
A Q EEE R +K +E KV E R + E E LQ ++ Q+
Sbjct: 2013 AEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQK 2072
Query: 164 QAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSD-----SEDEAA 218
+ + +A + E+E ++ Q+E E RR E+++ +E EAA
Sbjct: 2073 RLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAA 2132
Query: 219 PSPLQPALRPNPTAILDEAPKPKRKVEVWEQS 250
S Q ++EA + K+ E Q+
Sbjct: 2133 QSRRQ----------VEEAERLKQSAEEQAQA 2154
Score = 31.2 bits (69), Expect = 1.3
Identities = 23/114 (20%), Positives = 52/114 (45%), Gaps = 19/114 (16%)
Query: 114 LEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAML 173
+EEEE+ +++R +E E L ++ + ++ A +A
Sbjct: 1371 MEEEERLAEQQRAEER-------------------ERLAEVEAALEKQRQLAEAHAQAKA 1411
Query: 174 RQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQPALR 227
+ R ++E ++R Q+E +E AA+ + +KR + E+ +++ + +Q R
Sbjct: 1412 QAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKAR 1465
Score = 31.2 bits (69), Expect = 1.3
Identities = 35/135 (25%), Positives = 59/135 (43%), Gaps = 26/135 (19%)
Query: 109 QAEKLLEEE------------EKRVQKEREDEELNNPMKVL---------ENRTKDSKLE 147
Q +LLEEE +KR + E E ++ M+VL E+R+ K +
Sbjct: 1754 QQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSK 1813
Query: 148 MEVLENLQELKDLNQRQAHVDF--EAMLRQHRLSEEERRRQQQEEDE---QETAALLEEA 202
+ ++L + A + E RQ +L+EE+ RQ+ E + ++ AA+ E
Sbjct: 1814 QRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEAT 1873
Query: 203 RKRRLLEDSDSEDEA 217
R + E + E EA
Sbjct: 1874 RLKTEAEIALKEKEA 1888
Score = 31.2 bits (69), Expect = 1.3
Identities = 34/141 (24%), Positives = 65/141 (46%), Gaps = 15/141 (10%)
Query: 115 EEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDF----- 169
E EE RVQ ERE + ++ E + ++ + + Q + +++A +
Sbjct: 2119 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2178
Query: 170 --EAMLRQHRL--SEEERRRQQQEEDEQETAALLEEARKRRL-LEDSDSEDEAAPSPLQP 224
+A LRQ + +E E+ ++ E+ ++ A + +E RL LE++D + LQ
Sbjct: 2179 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ- 2237
Query: 225 ALRPNPTAILDEAPKPKRKVE 245
L+ T EA + + +VE
Sbjct: 2238 RLKAEAT----EAARQRSQVE 2254
Score = 30.8 bits (68), Expect = 1.7
Identities = 35/137 (25%), Positives = 63/137 (45%), Gaps = 30/137 (21%)
Query: 109 QAEKLLEEEEKRVQK----EREDEELNNPMKVLENRTKDSKLEMEVLEN----------- 153
Q + LLEE E+ +K +R ++ N +K E + K ++E + +
Sbjct: 1277 QEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGS 1336
Query: 154 ---LQELKDLNQRQAHVDFEAMLRQH---------RLSEEERRRQQQEEDEQETAALLEE 201
+QE DL R + + + Q+ R+ EEER +QQ +E+E A +E
Sbjct: 1337 ESVIQEYVDL--RTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEA 1394
Query: 202 A-RKRRLLEDSDSEDEA 217
A K+R L ++ ++ +A
Sbjct: 1395 ALEKQRQLAEAHAQAKA 1411
Score = 30.8 bits (68), Expect = 1.7
Identities = 44/214 (20%), Positives = 81/214 (37%), Gaps = 31/214 (14%)
Query: 90 KTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEME 149
+++ E+T + E + +L EEE+R + +E + + E + K +E
Sbjct: 1979 RSNAEDTLRSKEQAELEAARQRQLAAEEERR--RREAEERVQKSLAAEEEAARQRKAALE 2036
Query: 150 VLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLE 209
+E L+ ++ E R R++ E++ L +EA ++RL
Sbjct: 2037 EVERLKA--------------------KVEEARRLRERAEQESARQLQLAQEAAQKRLQA 2076
Query: 210 DSDSEDEAA---PSPLQPALRPNPTAILD----EAPKPKRKVEVWEQSVGSLGSRPPLSR 262
+ + A LQ L+ ++LD EA +R E E++ SR
Sbjct: 2077 EEKAHAFAVQQKEQELQQTLQ-QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR 2135
Query: 263 LVVVKKAKADPDC-SNGQPQAAPTPGAPQNRKEA 295
V + + Q +A A + RKEA
Sbjct: 2136 RQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2169
Score = 30.8 bits (68), Expect = 1.7
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 13/108 (12%)
Query: 110 AEKLLEEEEKRV------------QKEREDEELNNPMKVLENRTKD-SKLEMEVLENLQE 156
AEKL +E E+ QK+ D E+ K E + +++E E+ +
Sbjct: 2162 AEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2221
Query: 157 LKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARK 204
L++ + ++ +D E + +E R+R Q EE+ +EE K
Sbjct: 2222 LEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSK 2269
Score = 30.4 bits (67), Expect = 2.2
Identities = 31/105 (29%), Positives = 50/105 (47%), Gaps = 13/105 (12%)
Query: 110 AEKLLEEEEKRVQKE---REDEELNNPMKVLEN----RTKDSKLEM--EVLENLQ----E 156
AEK+L+E+ + VQ+ + + EL K L R ++ K +M ++ E Q
Sbjct: 2335 AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT 2394
Query: 157 LKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEE 201
L+ QRQ + EA + R++E R + + EED Q EE
Sbjct: 2395 LEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEE 2439
Score = 29.6 bits (65), Expect = 3.8
Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 6/93 (6%)
Query: 113 LLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAM 172
L EE EK Q E L+ + + ++L E+L + + L ++ +A+
Sbjct: 2293 LQEEAEKMKQVAEEAARLSVAAQ------EAARLRQLAEEDLAQQRALAEKMLKEKMQAV 2346
Query: 173 LRQHRLSEEERRRQQQEEDEQETAALLEEARKR 205
RL E QQQ+E QE A L+E +++
Sbjct: 2347 QEATRLKAEAELLQQQKELAQEQARRLQEDKEQ 2379
Score = 29.3 bits (64), Expect = 4.9
Identities = 26/111 (23%), Positives = 50/111 (45%), Gaps = 3/111 (2%)
Query: 116 EEEKRVQKEREDEELNNPMKVLENRTKDS-KLEMEVLENLQELKDLNQRQAHVDFEAMLR 174
EE+ Q+E ++EL ++ E + E E++ E + Q++ ++ E
Sbjct: 1707 EEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1766
Query: 175 QHRLSEEERRRQQQEEDEQETAALLEE--ARKRRLLEDSDSEDEAAPSPLQ 223
Q + ++RQ+ E + + A +E A K R E+S S E + L+
Sbjct: 1767 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLE 1817
Score = 28.5 bits (62), Expect = 8.4
Identities = 27/110 (24%), Positives = 52/110 (47%), Gaps = 9/110 (8%)
Query: 112 KLLEEEEKRVQK----EREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHV 167
+L EE E+R Q+ ER EE ++ + + ++ E + + K L Q +A
Sbjct: 1632 QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK 1691
Query: 168 DFEAMLRQHRL---SEEERRRQQQ--EEDEQETAALLEEARKRRLLEDSD 212
E R+ R +EE+ RQ++ E++ ++ L E ++RL + +
Sbjct: 1692 QKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQE 1741
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,499,804
Number of Sequences: 37866
Number of extensions: 811509
Number of successful extensions: 13252
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 313
Number of HSP's successfully gapped in prelim test: 923
Number of HSP's that attempted gapping in prelim test: 6720
Number of HSP's gapped (non-prelim): 4406
length of query: 323
length of database: 18,247,518
effective HSP length: 102
effective length of query: 221
effective length of database: 14,385,186
effective search space: 3179126106
effective search space used: 3179126106
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.