BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|31542331 cysteine-rich, angiogenic inducer, 61 [Homo sapiens] (381 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|31542331 cysteine-rich, angiogenic inducer, 61 [Homo sapiens] 819 0.0 gi|4503123 connective tissue growth factor [Homo sapiens] 360 2e-99 gi|4505423 nephroblastoma overexpressed precursor [Homo sapiens] 315 4e-86 gi|4507921 WNT1 inducible signaling pathway protein 1 isoform 1 ... 287 1e-77 gi|38202241 WNT1 inducible signaling pathway protein 3 isoform 3... 229 3e-60 gi|4507925 WNT1 inducible signaling pathway protein 3 isoform 1 ... 229 3e-60 gi|4507923 WNT1 inducible signaling pathway protein 2 precursor ... 198 8e-51 gi|18491000 WNT1 inducible signaling pathway protein 1 isoform 2... 150 2e-36 gi|22129776 HtrA serine peptidase 3 [Homo sapiens] 47 2e-05 gi|4759146 slit homolog 2 [Homo sapiens] 46 5e-05 gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 46 5e-05 gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens] 46 6e-05 gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 45 1e-04 gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens] 44 2e-04 gi|108773804 Fraser syndrome 1 [Homo sapiens] 44 2e-04 gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens] 44 3e-04 gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens] 42 7e-04 gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens] 42 7e-04 gi|223029476 NEL-like protein 2 isoform d [Homo sapiens] 42 7e-04 gi|223029474 NEL-like protein 2 isoform c [Homo sapiens] 42 7e-04 gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens] 42 7e-04 gi|223029470 NEL-like protein 2 isoform a [Homo sapiens] 42 7e-04 gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens] 42 7e-04 gi|24308541 HtrA serine peptidase 4 precursor [Homo sapiens] 42 7e-04 gi|34147715 chordin-like 1 isoform 3 precursor [Homo sapiens] 42 0.001 gi|221316563 chordin-like 1 isoform 2 precursor [Homo sapiens] 42 0.001 gi|221316561 chordin-like 1 isoform 1 precursor [Homo sapiens] 42 0.001 gi|33598931 scavenger receptor class F, member 1 isoform 3 precu... 42 0.001 gi|33598929 scavenger receptor class F, member 1 isoform 1 precu... 42 0.001 gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 41 0.002 >gi|31542331 cysteine-rich, angiogenic inducer, 61 [Homo sapiens] Length = 381 Score = 819 bits (2115), Expect = 0.0 Identities = 381/381 (100%), Positives = 381/381 (100%) Query: 1 MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQL 60 MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQL Sbjct: 1 MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQL 60 Query: 61 NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQ 120 NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQ Sbjct: 61 NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQ 120 Query: 121 CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG 180 CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG Sbjct: 121 CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG 180 Query: 181 KELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCS 240 KELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCS Sbjct: 181 KELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCS 240 Query: 241 KTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTY 300 KTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTY Sbjct: 241 KTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTY 300 Query: 301 AGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP 360 AGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP Sbjct: 301 AGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP 360 Query: 361 HANEAAFPFYRLFNDIHKFRD 381 HANEAAFPFYRLFNDIHKFRD Sbjct: 361 HANEAAFPFYRLFNDIHKFRD 381 >gi|4503123 connective tissue growth factor [Homo sapiens] Length = 349 Score = 360 bits (923), Expect = 2e-99 Identities = 175/373 (46%), Positives = 232/373 (62%), Gaps = 40/373 (10%) Query: 9 LALVVTLLHLTRLALS-TCPAACHCPLE-APKCAPGVGLVRDGCGCCKVCAKQLNEDCSK 66 +A VV L +R A+ C C CP E AP+C GV LV DGCGCC+VCAKQL E C++ Sbjct: 11 VAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTE 70 Query: 67 TQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDG 126 PCD KGL C+FG+ + G+C A+ +G PC + +Y++GESFQ +CK+QCTC+DG Sbjct: 71 RDPCDPHKGLFCDFGSPANRKIGVCTAK-DGAPCIFGGTVYRSGESFQSSCKYQCTCLDG 129 Query: 127 AVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFD 186 AVGC+PLC ++ LP+ CP PR VK+ G+CCEEWVCDE +DQ Sbjct: 130 AVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEP------KDQT---------- 173 Query: 187 ASEVELTRNNELIAVGKGSSLKRLP-VFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGT 245 VG + RL FG +P ++ C+VQTT WS CSKTCG Sbjct: 174 -------------VVGPALAAYRLEDTFGPDPTMIR-----ANCLVQTTEWSACSKTCGM 215 Query: 246 GISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLS 305 GISTRVTNDN CRL K++R+C VRPC + ++KKGKKC +T K +P++F +GC S Sbjct: 216 GISTRVTNDNASCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKISKPIKFELSGCTS 275 Query: 306 VKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEA 365 +K YR K+CG C DGRCCTP T T+ + F+C DGE KN+M I++C C+YNCP N+ Sbjct: 276 MKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDI 335 Query: 366 AFPFY--RLFNDI 376 Y +++ D+ Sbjct: 336 FESLYYRKMYGDM 348 >gi|4505423 nephroblastoma overexpressed precursor [Homo sapiens] Length = 357 Score = 315 bits (807), Expect = 4e-86 Identities = 160/364 (43%), Positives = 208/364 (57%), Gaps = 39/364 (10%) Query: 7 RALALVVTLLHLTRLALST--CPAAC--HCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNE 62 + L L LLHL +T CP C CP P CAPGV V DGC CC VCA+Q E Sbjct: 14 QCLCLTFLLLHLLGQVAATQRCPPQCPGRCPATPPTCAPGVRAVLDGCSCCLVCARQRGE 73 Query: 63 DCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCT 122 CS +PCD + GL C+ A + GIC A EG C ++ IY++GE FQP+CK QCT Sbjct: 74 SCSDLEPCDESSGLYCDRSADPSNQTGICTAV-EGDNCVFDGVIYRSGEKFQPSCKFQCT 132 Query: 123 CIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKE 182 C DG +GC+P C ++ LP CP PR V+V G+CCE+W+C D ++D L G Sbjct: 133 CRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPD-------EEDSLGGLT 185 Query: 183 LGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKT 242 L A E T E+ SS+ CI QTT W+ CSK+ Sbjct: 186 LA--AYRPEATLGVEV----SDSSV--------------------NCIEQTTEWTACSKS 219 Query: 243 CGTGISTRVTNDNPECRLVKETRICEVRPCGQ-PVYSSLKKGKKCSKTKKSPEPVRFTYA 301 CG G STRVTN N +C ++K+TR+C VRPC Q P + KKGKKC +TKKS + + + Sbjct: 220 CGMGFSTRVTNRNRQCEMLKQTRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFK 279 Query: 302 GCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPH 361 C S+ Y+P++CG C DGRCCTP T+T++ F+C G+ K VM+I +C C+ NCP Sbjct: 280 NCTSLHTYKPRFCGVCSDGRCCTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPK 339 Query: 362 ANEA 365 NEA Sbjct: 340 NNEA 343 >gi|4507921 WNT1 inducible signaling pathway protein 1 isoform 1 precursor [Homo sapiens] Length = 367 Score = 287 bits (735), Expect = 1e-77 Identities = 149/389 (38%), Positives = 210/389 (53%), Gaps = 54/389 (13%) Query: 2 SSRIARALALVVTLLHLTRLALST-------CPAACHCPLEAPKCAPGVGLVRDGCGCCK 54 S+ +A AL+ T + T L C C CP P+C GV L+ DGC CCK Sbjct: 18 STVLATALSPAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPPRCPLGVSLITDGCECCK 77 Query: 55 VCAKQLNEDCSKTQPCDHTKGLECNF-GASSTALKGICRAQSEGRPCEYNSRIYQNGESF 113 +CA+QL ++C++ CD +GL C++ G G+C AQ G C + Y NG+SF Sbjct: 78 MCAQQLGDNCTEAAICDPHRGLYCDYSGDRPRYAIGVC-AQVVGVGCVLDGVRYNNGQSF 136 Query: 114 QPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPME 173 QPNCK+ CTCIDGAVGC PLC + P L CP+PR V + G CCE+WVC++D+ K P + Sbjct: 137 QPNCKYNCTCIDGAVGCTPLC-LRVRPPRLWCPHPRRVSIPGHCCEQWVCEDDA-KRPRK 194 Query: 174 DQDGLLGKELGFDA-SEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQ 232 G FDA EVE N CI Sbjct: 195 TAPRDTG---AFDAVGEVEAWHRN--------------------------------CIAY 219 Query: 233 TTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKS 292 T+ WS CS +CG G+STR++N N +C +E+R+C +RPC +++ +K GKKC + Sbjct: 220 TSPWSPCSTSCGLGVSTRISNVNAQCWPEQESRLCNLRPCDVDIHTLIKAGKKCLAVYQP 279 Query: 293 PEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQS 352 + FT AGC+S + Y+PKYCG C+D RCC P ++T+ + F+C DG FS+ V+ I + Sbjct: 280 EASMNFTLAGCISTRSYQPKYCGVCMDNRCCIPYKSKTIDVSFQCPDGLGFSRQVLWINA 339 Query: 353 CKCNYNCPHANEAAFPFYRLFNDIHKFRD 381 C CN +C + N+ +F D+ + D Sbjct: 340 CFCNLSCRNPND-------IFADLESYPD 361 >gi|38202241 WNT1 inducible signaling pathway protein 3 isoform 3 [Homo sapiens] Length = 372 Score = 229 bits (584), Expect = 3e-60 Identities = 121/337 (35%), Positives = 171/337 (50%), Gaps = 46/337 (13%) Query: 26 CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASST 85 C C CP + P+C PGV LVRDGCGCCK+CAKQ E C++ CD KGL C++ Sbjct: 66 CHWPCKCPQQKPRCPPGVSLVRDGCGCCKICAKQPGEICNEADLCDPHKGLYCDYSVDRP 125 Query: 86 ALK-GICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLG 144 + G+C A CE+N Y NG+ FQPN C C+ GA+GC PL Sbjct: 126 RYETGVC-AYLVAVGCEFNQVHYHNGQVFQPNPLFSCLCVSGAIGCTPLF---------- 174 Query: 145 CPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKG 204 + K+ G C G G + D S L E + Sbjct: 175 -----IPKLAGSHCS-----------------GAKGGKKS-DQSNCSL----EPLLQQLS 207 Query: 205 SSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKET 264 +S K +P + P I +KC+VQ T W+ CS+TCG GIS RVTN+N C + KE Sbjct: 208 TSYKTMPAYRNLPLIWK-----KKCLVQATKWTPCSRTCGMGISNRVTNENSNCEMRKEK 262 Query: 265 RICEVRPCGQPVYSSLK--KGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRC 322 R+C ++PC + ++K KGK C T + + +F ++GC S + Y+P +CG C+D RC Sbjct: 263 RLCYIQPCDSNILKTIKIPKGKTCQPTFQLSKAEKFVFSGCSSTQSYKPTFCGICLDKRC 322 Query: 323 CTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNC 359 C P ++ + ++F C + +F ++ I SC C NC Sbjct: 323 CIPNKSKMITIQFDCPNEGSFKWKMLWITSCVCQRNC 359 >gi|4507925 WNT1 inducible signaling pathway protein 3 isoform 1 [Homo sapiens] Length = 354 Score = 229 bits (584), Expect = 3e-60 Identities = 121/337 (35%), Positives = 171/337 (50%), Gaps = 46/337 (13%) Query: 26 CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASST 85 C C CP + P+C PGV LVRDGCGCCK+CAKQ E C++ CD KGL C++ Sbjct: 48 CHWPCKCPQQKPRCPPGVSLVRDGCGCCKICAKQPGEICNEADLCDPHKGLYCDYSVDRP 107 Query: 86 ALK-GICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLG 144 + G+C A CE+N Y NG+ FQPN C C+ GA+GC PL Sbjct: 108 RYETGVC-AYLVAVGCEFNQVHYHNGQVFQPNPLFSCLCVSGAIGCTPLF---------- 156 Query: 145 CPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKG 204 + K+ G C G G + D S L E + Sbjct: 157 -----IPKLAGSHCS-----------------GAKGGKKS-DQSNCSL----EPLLQQLS 189 Query: 205 SSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKET 264 +S K +P + P I +KC+VQ T W+ CS+TCG GIS RVTN+N C + KE Sbjct: 190 TSYKTMPAYRNLPLIWK-----KKCLVQATKWTPCSRTCGMGISNRVTNENSNCEMRKEK 244 Query: 265 RICEVRPCGQPVYSSLK--KGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRC 322 R+C ++PC + ++K KGK C T + + +F ++GC S + Y+P +CG C+D RC Sbjct: 245 RLCYIQPCDSNILKTIKIPKGKTCQPTFQLSKAEKFVFSGCSSTQSYKPTFCGICLDKRC 304 Query: 323 CTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNC 359 C P ++ + ++F C + +F ++ I SC C NC Sbjct: 305 CIPNKSKMITIQFDCPNEGSFKWKMLWITSCVCQRNC 341 >gi|4507923 WNT1 inducible signaling pathway protein 2 precursor [Homo sapiens] Length = 250 Score = 198 bits (503), Expect = 8e-51 Identities = 96/256 (37%), Positives = 132/256 (51%), Gaps = 37/256 (14%) Query: 18 LTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLE 77 L+++ CP C CP P+C GV LV DGCGCC+VCA++L E C + CD ++GL Sbjct: 18 LSKVRTQLCPTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQGLV 77 Query: 78 CNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQE 137 C GA +C + CE N R+Y+ GE+FQP+C +C C DG C+PLC ++ Sbjct: 78 CQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQPHCSIRCRCEDGGFTCVPLCSED 137 Query: 138 LSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNE 197 + LP+ CP+PR V+V G+CC EWVC + Sbjct: 138 VRLPSWDCPHPRRVEVLGKCCPEWVCGQ-------------------------------- 165 Query: 198 LIAVGKGSSLKRLPVFGMEPRILYNPL-QGQKCIVQTTSWSQCSKTCGTGISTRVTNDNP 256 G G + LP G + L + L G C +T+W CS TCG G++TRV+N N Sbjct: 166 ----GGGLGTQPLPAQGPQFSGLVSSLPPGVPCPEWSTAWGPCSTTCGLGMATRVSNQNR 221 Query: 257 ECRLVKETRICEVRPC 272 CRL + R+C RPC Sbjct: 222 FCRLETQRRLCLSRPC 237 >gi|18491000 WNT1 inducible signaling pathway protein 1 isoform 2 precursor [Homo sapiens] Length = 280 Score = 150 bits (378), Expect = 2e-36 Identities = 62/155 (40%), Positives = 97/155 (62%), Gaps = 7/155 (4%) Query: 227 QKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKC 286 + CI T+ WS CS +CG G+STR++N N +C +E+R+C +RPC +++ +K GKKC Sbjct: 127 RNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQESRLCNLRPCDVDIHTLIKAGKKC 186 Query: 287 SKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKN 346 + + FT AGC+S + Y+PKYCG C+D RCC P ++T+ + F+C DG FS+ Sbjct: 187 LAVYQPEASMNFTLAGCISTRSYQPKYCGVCMDNRCCIPYKSKTIDVSFQCPDGLGFSRQ 246 Query: 347 VMMIQSCKCNYNCPHANEAAFPFYRLFNDIHKFRD 381 V+ I +C CN +C + N+ +F D+ + D Sbjct: 247 VLWINACFCNLSCRNPND-------IFADLESYPD 274 Score = 69.3 bits (168), Expect = 5e-12 Identities = 35/98 (35%), Positives = 51/98 (52%), Gaps = 8/98 (8%) Query: 2 SSRIARALALVVTLLHLTRLALST-------CPAACHCPLEAPKCAPGVGLVRDGCGCCK 54 S+ +A AL+ T + T L C C CP P+C GV L+ DGC CCK Sbjct: 18 STVLATALSPAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPPRCPLGVSLITDGCECCK 77 Query: 55 VCAKQLNEDCSKTQPCDHTKGLECNF-GASSTALKGIC 91 +CA+QL ++C++ CD +GL C++ G G+C Sbjct: 78 MCAQQLGDNCTEAAICDPHRGLYCDYSGDRPRYAIGVC 115 >gi|22129776 HtrA serine peptidase 3 [Homo sapiens] Length = 453 Score = 47.4 bits (111), Expect = 2e-05 Identities = 38/111 (34%), Positives = 48/111 (43%), Gaps = 21/111 (18%) Query: 6 ARALALVVTLLHLTRLALSTCPAACHCPLE-------APKCAPGVGLVRDGCGCCKVCAK 58 ARAL L L LAL+ P A CP +P+C PG G V D C CC VCA Sbjct: 3 ARALLLAA----LAALALAREPPAAPCPARCDVSRCPSPRC-PG-GYVPDLCNCCLVCA- 55 Query: 59 QLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQN 109 S+ +PC C G S ++G+CR + C + Y N Sbjct: 56 -----ASEGEPCGGPLDSPC--GESLECVRGLCRCRWSHAVCGTDGHTYAN 99 >gi|4759146 slit homolog 2 [Homo sapiens] Length = 1529 Score = 46.2 bits (108), Expect = 5e-05 Identities = 21/57 (36%), Positives = 27/57 (47%), Gaps = 1/57 (1%) Query: 300 YAGCLSVKKYRPKYC-GSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKC 355 YA C + KK C G C G+CC P ++ K F C DG +F V + C C Sbjct: 1468 YAACQTTKKVSRLECRGGCAGGQCCGPLRSKRRKYSFECTDGSSFVDEVEKVVKCGC 1524 Score = 32.3 bits (72), Expect = 0.73 Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 23/95 (24%) Query: 67 TQPCDHTKGLECNFG-ASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCID 125 + PC H G C+ IC EG CE N ++ + C++ TC+D Sbjct: 963 SNPCKH--GGTCHLKEGEEDGFWCICADGFEGENCEVNVDDCEDND-----CENNSTCVD 1015 Query: 126 GAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEE 160 G LCP E TG+ CEE Sbjct: 1016 GINNYTCLCPPE---------------YTGELCEE 1035 >gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] Length = 1541 Score = 46.2 bits (108), Expect = 5e-05 Identities = 42/138 (30%), Positives = 47/138 (34%), Gaps = 26/138 (18%) Query: 26 CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQP-------CDHTKGLEC 78 C C CP E P C P G C A C + P C+ G C Sbjct: 1171 CAQMCQCPGENPACHPAT-------GTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCG--C 1221 Query: 79 NFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIP-----L 133 G S A G CR + + N Q F PNC H C C GA C P L Sbjct: 1222 LNGGSCDAATGACRCPTGFLGTDCNLTCPQG--RFGPNCTHVCGCGQGA-ACDPVTGTCL 1278 Query: 134 CPQELS--LPNLGCPNPR 149 CP + GCP R Sbjct: 1279 CPPGRAGVRCERGCPQNR 1296 Score = 38.1 bits (87), Expect = 0.013 Identities = 41/130 (31%), Positives = 47/130 (36%), Gaps = 21/130 (16%) Query: 26 CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGL-ECNFGASS 84 CPA H C PG G GC + C DC PCD GL C G S Sbjct: 1408 CPAGFHGHFCERGCEPG----SFGEGCHQRC------DCDGGAPCDPVTGLCLCPPGRSG 1457 Query: 85 TALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQ--ELSLPN 142 CR G C + G P QC C+DG +G P C + L LP Sbjct: 1458 ATCNLDCRRGQFGPSCTLHCDC-GGGADCDP-VSGQCHCVDGYMG--PTCREGGPLRLPE 1513 Query: 143 LGCPNPRLVK 152 NP L + Sbjct: 1514 ----NPSLAQ 1519 Score = 34.3 bits (77), Expect = 0.19 Identities = 32/104 (30%), Positives = 41/104 (39%), Gaps = 23/104 (22%) Query: 27 PAACHCPLEAPKCAPGVGLVRDGCGCCKVC-AKQLNEDCSKTQPCDHTKGLECNFGASST 85 PA HC CAPG G C + C DCS PC+ + G S Sbjct: 840 PATGHC-----SCAPGW----TGFSCQRACDTGHWGPDCS--HPCNCSAG-----HGSCD 883 Query: 86 ALKGICRAQSE--GRPCEYNSRIYQNGESFQPNCKHQCTCIDGA 127 A+ G+C ++ G CE G F P C+ +C C GA Sbjct: 884 AISGLCLCEAGYVGPRCEQQC---PQGH-FGPGCEQRCQCQHGA 923 Score = 33.5 bits (75), Expect = 0.33 Identities = 43/159 (27%), Positives = 58/159 (36%), Gaps = 36/159 (22%) Query: 26 CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNF----- 80 C +AC+C A A G C A + C++T P HT G C+ Sbjct: 956 CRSACNCTAGAACDAVN--------GSCLCPAGRRGPRCAETCPA-HTYGHNCSQACACF 1006 Query: 81 -GASSTALKGICRAQSE--GRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPL---- 133 GAS + G C G C G+ NC+H C C +G C P+ Sbjct: 1007 NGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGD----NCRHSCLCQNGGT-CDPVSGHC 1061 Query: 134 -CPQELSLPNLGCPN---PRLVKV----TGQCCEEWVCD 164 CP+ L C PR V+ +G C +CD Sbjct: 1062 ACPE--GWAGLACEKECLPRDVRAGCRHSGGCLNGGLCD 1098 >gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens] Length = 814 Score = 45.8 bits (107), Expect = 6e-05 Identities = 72/292 (24%), Positives = 101/292 (34%), Gaps = 61/292 (20%) Query: 26 CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKT----QPCDHTKGLECNFG 81 CPA C L+ + A GV DG C + C PC H Sbjct: 421 CPA---CELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHP-------- 469 Query: 82 ASSTALKGICRAQSEGRPCEYNSRIYQNGESF--QPNCKHQCTCIDGAVGCIPLCPQELS 139 T G C + C Y+S++Y NG++F + H C C DG V C + Sbjct: 470 ---TQPPGACCPSCDS--CTYHSQVYANGQNFTDADSPCHACHCQDGTVTC-----SLVD 519 Query: 140 LPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELI 199 P C P+ GQCC D I +E++ + G+ + R E Sbjct: 520 CPPTTCARPQ--SGPGQCCPRC---PDCI---LEEEVFVDGESFSHPRDPCQECRCQEGH 571 Query: 200 AVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECR 259 A + R P +PL G C + + K +G +D CR Sbjct: 572 AHCQPRPCPRAP--------CAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSD--PCR 621 Query: 260 LVK--------ETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGC 303 L + R C PC +PV L G+ C + +P P AGC Sbjct: 622 LCRCLSGNVQCLARRCVPLPCPEPV---LLPGECCPQCPAAPAP-----AGC 665 Score = 42.0 bits (97), Expect = 0.001 Identities = 20/61 (32%), Positives = 27/61 (44%), Gaps = 11/61 (18%) Query: 98 RPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQC 157 R C N + Y NGE+F P+ C C++G + C + P CP P G C Sbjct: 136 RGCSQNGQTYGNGETFSPDACTTCRCLEGTITC-----NQKPCPRGPCPEP------GAC 184 Query: 158 C 158 C Sbjct: 185 C 185 Score = 39.3 bits (90), Expect = 0.006 Identities = 29/80 (36%), Positives = 38/80 (47%), Gaps = 14/80 (17%) Query: 87 LKGICRAQSEGRPCEYNSRIYQNGESFQPN--CKHQCTCIDGAVGCIPLCPQELSLPNLG 144 L G C +G C N R +++GE C H C C +G+V C P L P + Sbjct: 299 LPGTCCPVCDG--CFLNGREHRSGEPVGSGDPCSH-CRCANGSVQCEP-----LPCPPVP 350 Query: 145 CPNPRLVKVTGQCCEEWVCD 164 C +P K+ GQCC VCD Sbjct: 351 CRHPG--KIPGQCCP--VCD 366 Score = 37.7 bits (86), Expect = 0.017 Identities = 40/142 (28%), Positives = 51/142 (35%), Gaps = 24/142 (16%) Query: 29 ACHCPLEAPKCAPGVGLVRDGC-GCCKVCAKQLNEDCSKTQPCDHTKGLE----CNFGAS 83 AC C A C P L C GC + N + C + LE CN Sbjct: 116 ACVCQDGAAHCGPQAHLPH--CRGCSQNGQTYGNGETFSPDACTTCRCLEGTITCN---Q 170 Query: 84 STALKGICRAQSEGRP-----CEYNSRIYQNGESF--QPNCKHQCTCIDGAVGCIPLCPQ 136 +G C P C+Y ++Y+ G +F N QCTC+ V C+ Sbjct: 171 KPCPRGPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCM----- 225 Query: 137 ELSLPNLGCPNPRLVKVTGQCC 158 L P CP P V G CC Sbjct: 226 ALKCPPSPCPEP--VLRPGHCC 245 Score = 34.7 bits (78), Expect = 0.15 Identities = 42/160 (26%), Positives = 56/160 (35%), Gaps = 30/160 (18%) Query: 21 LALSTCPAACHCPLEAP-KCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECN 79 LA P C P+ P +C P GC + A + P D + C Sbjct: 633 LARRCVPLPCPEPVLLPGECCPQCPAAPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCL 692 Query: 80 FGASSTAL------------KGICRAQSEGRPCEYNSRIYQNGESF-QPNCK-HQCTCID 125 G+ S +G C +G C Y + + +GE F P H C C + Sbjct: 693 DGSVSCQRLPCPPAPCAHPRQGPCCPSCDG--CLYQGKEFASGERFPSPTAACHLCLCWE 750 Query: 126 GAVGCIP-LCPQELSLPNLGCPNPRLVKVTGQCCEEWVCD 164 G+V C P C L CP P G CC + CD Sbjct: 751 GSVSCEPKACAPAL------CPFP----ARGDCCPD--CD 778 >gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] Length = 1503 Score = 45.1 bits (105), Expect = 1e-04 Identities = 44/163 (26%), Positives = 58/163 (35%), Gaps = 38/163 (23%) Query: 26 CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKT----QPCDHTKGLECNFG 81 CPA C L+ + A GV DG C + C PC H Sbjct: 363 CPA---CELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHP-------- 411 Query: 82 ASSTALKGICRAQSEGRPCEYNSRIYQNGESF--QPNCKHQCTCIDGAVGCIPLCPQELS 139 T G C + C Y+S++Y NG++F + H C C DG V C + Sbjct: 412 ---TQPPGACCPSCDS--CTYHSQVYANGQNFTDADSPCHACHCQDGTVTC-----SLVD 461 Query: 140 LPNLGCPNPRLVKVTGQCC---------EEWVCDEDSIKDPME 173 P C P+ GQCC EE D +S P + Sbjct: 462 CPPTTCARPQ--SGPGQCCPRCPDCILEEEVFVDGESFSHPRD 502 Score = 40.4 bits (93), Expect = 0.003 Identities = 23/62 (37%), Positives = 30/62 (48%), Gaps = 9/62 (14%) Query: 98 RPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCI-PLCPQELSLPNLGCPNPRLVKVTGQ 156 R C N + Y NGE+F P+ C C+ GAV C P C + L + C P G+ Sbjct: 136 RGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGPSCSELNCLES--CTPP------GE 187 Query: 157 CC 158 CC Sbjct: 188 CC 189 Score = 39.7 bits (91), Expect = 0.005 Identities = 35/131 (26%), Positives = 49/131 (37%), Gaps = 28/131 (21%) Query: 52 CCKVCAKQLNEDCSKTQ-------PCDHTKGLECNFGASSTALKGICRAQSEGRP----- 99 CC +C + Q PC + LE + +C + P Sbjct: 188 CCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCP 247 Query: 100 ----CEYNSRIYQNGESFQPN--CKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKV 153 C N R +++GE C H C C +G+V C P L P + C +P K+ Sbjct: 248 VCDGCFLNGREHRSGEPVGSGDPCSH-CRCANGSVQCEP-----LPCPPVPCRHPG--KI 299 Query: 154 TGQCCEEWVCD 164 GQCC VCD Sbjct: 300 PGQCCP--VCD 308 Score = 35.0 bits (79), Expect = 0.11 Identities = 31/88 (35%), Positives = 37/88 (42%), Gaps = 10/88 (11%) Query: 100 CEYNSRIYQNGESFQPNCK--HQCTCIDGAVGCIPLCPQELSLPNL-GCPNPRLVKVTGQ 156 CE+ R Y+ GESFQP C C G L P+L GCP +L+ Q Sbjct: 954 CEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQ 1013 Query: 157 -CCEEWVCDEDSIKDPMEDQDGLLGKEL 183 CC C E +GLLG EL Sbjct: 1014 HCCP--TCAEAL----SNCSEGLLGSEL 1035 Score = 34.3 bits (77), Expect = 0.19 Identities = 40/153 (26%), Positives = 52/153 (33%), Gaps = 47/153 (30%) Query: 26 CPAACHCPLEAPKCAPGVGLVRD-------GCGCCKVCAKQLNEDCSKTQ----PCDHTK 74 CPA CP PG R G C + + C + PC H + Sbjct: 598 CPAPAGCP------RPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPR 651 Query: 75 GLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESF-QPNCK-HQCTCIDGAVGCIP 132 +G C +G C Y + + +GE F P H C C +G+V C P Sbjct: 652 -------------QGPCCPSCDG--CLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEP 696 Query: 133 -LCPQELSLPNLGCPNPRLVKVTGQCCEEWVCD 164 C L CP P G CC + CD Sbjct: 697 KACAPAL------CPFP----ARGDCCPD--CD 717 Score = 29.3 bits (64), Expect = 6.2 Identities = 38/160 (23%), Positives = 54/160 (33%), Gaps = 42/160 (26%) Query: 26 CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSK------------------- 66 CP+ CP P L CC CA+ L+ +CS+ Sbjct: 996 CPSLVGCP-------PSQLLPPGPQHCCPTCAEALS-NCSEGLLGSELAPPDPCYTCQCQ 1047 Query: 67 --TQPCDHTK--GLECNFGASST---ALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKH 119 T C H L C T + +CRA ++ C + R +GE + + Sbjct: 1048 DLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQS--CVHQGREVASGERWTVDTCT 1105 Query: 120 QCTCIDGAVGCIPLCPQELSLPNLGC-PNPRLVKVTGQCC 158 C+C+ G V C Q L C P+ G CC Sbjct: 1106 SCSCMAGTVRC-----QSQRCSPLSCGPDKAPALSPGSCC 1140 >gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens] Length = 1036 Score = 44.3 bits (103), Expect = 2e-04 Identities = 45/147 (30%), Positives = 57/147 (38%), Gaps = 21/147 (14%) Query: 11 LVVTLLHLTRLALSTCPAACHC-PLEAPKC-----APGVGLVRDGCGCCKVCAKQLNEDC 64 L+V+LL L L + A C P + KC PG +V+ CGCC CA Q NE C Sbjct: 16 LLVSLLGLLLLLARSGTRALVCLPCDESKCEEPRNCPG-SIVQGVCGCCYTCASQRNESC 74 Query: 65 SKT----QPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQP---NC 117 T CD +GL C L G + E CE + F+P N Sbjct: 75 GGTFGIYGTCD--RGLRC---VIRPPLNGDSLTEYEAGVCEDENWTDDQLLGFKPCNENL 129 Query: 118 KHQCTCIDGAVGC--IPLCPQELSLPN 142 C I+G C I C P+ Sbjct: 130 IAGCNIINGKCECNTIRTCSNPFEFPS 156 Score = 39.3 bits (90), Expect = 0.006 Identities = 45/158 (28%), Positives = 63/158 (39%), Gaps = 29/158 (18%) Query: 23 LSTCPAACHCPLEAPKCAPGVGLVRDGCGCC-----------KVCAKQLNEDCSKTQPCD 71 LST P+ CH P G D C C +VC L ++ S+TQ Sbjct: 673 LST-PSICHAP-GGEYFVEGETWNIDSCTQCTCHSGRVLCETEVCPPLLCQNPSRTQDSC 730 Query: 72 HTKGLECNFGASSTALKGICRAQSEGRPCEYNSR-IYQNGESFQPNCKHQCTCIDGAVGC 130 + + F S + R S C+ + I+ ES++P+ C CID + C Sbjct: 731 CPQCTDQPFRPS------LSRNNSVPNYCKNDEGDIFLAAESWKPDVCTSCICIDSVISC 784 Query: 131 IPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSI 168 S P++ C P L K GQCC C ED+I Sbjct: 785 F-----SESCPSVSCERPVLRK--GQCCP--YCIEDTI 813 Score = 35.4 bits (80), Expect = 0.086 Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 12/70 (17%) Query: 100 CEYNSRIYQNGESFQPNCKHQCTCIDGAVGCI-PLCPQELSLPNLGCPNPRLVKVTGQCC 158 C N I +G+ ++ + C C++G C+ +C Q C NP VKV G+CC Sbjct: 403 CYANGLILAHGDRWREDDCTFCQCVNGERHCVATVCGQT-------CTNP--VKVPGECC 453 Query: 159 EEWVCDEDSI 168 VC+E +I Sbjct: 454 P--VCEEPTI 461 Score = 33.9 bits (76), Expect = 0.25 Identities = 29/125 (23%), Positives = 45/125 (36%), Gaps = 21/125 (16%) Query: 50 CGCCKVCAKQLNEDCSKTQPCDHT---KGLECNFGASSTALKGICRAQSEGRPCEYNSRI 106 C C +E C C+ KG C + T K + C ++ + Sbjct: 775 CICIDSVISCFSESCPSVS-CERPVLRKGQCCPYCIEDTIPKKVV--------CHFSGKA 825 Query: 107 YQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDED 166 Y + E + + C C+ G C +S P L C P + V G CC +C E Sbjct: 826 YADEERWDLDSCTHCYCLQGQTLC-----STVSCPPLPCVEP--INVEGSCCP--MCPEM 876 Query: 167 SIKDP 171 + +P Sbjct: 877 YVPEP 881 >gi|108773804 Fraser syndrome 1 [Homo sapiens] Length = 4011 Score = 43.9 bits (102), Expect = 2e-04 Identities = 29/110 (26%), Positives = 46/110 (41%), Gaps = 9/110 (8%) Query: 53 CKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICR--AQSEGRPCEYNSRIYQNG 110 C VC+ E QPC L C + +G C G+PC Y ++Q+G Sbjct: 113 CSVCSCNHGEVRCTPQPCPP---LSCGHQELAFIPEGSCCPVCVGLGKPCSYEGHVFQDG 169 Query: 111 ESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEE 160 E ++ + +C C +G C Q L + +V+V G+CC + Sbjct: 170 EDWRLSRCAKCLCRNGVAQCFTAQCQPLFCNQ----DETVVRVPGKCCPQ 215 Score = 43.1 bits (100), Expect = 4e-04 Identities = 26/87 (29%), Positives = 36/87 (41%), Gaps = 4/87 (4%) Query: 76 LECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCP 135 L CN + + G C Q R C ++Y++GE + N C C G V C Sbjct: 197 LFCNQDETVVRVPGKCCPQCSARSCSAAGQVYEHGEQWSENACTTCICDRGEV----RCH 252 Query: 136 QELSLPNLGCPNPRLVKVTGQCCEEWV 162 ++ LP + GQCCEE V Sbjct: 253 KQACLPLRCGKGQSRARRHGQCCEECV 279 Score = 31.2 bits (69), Expect = 1.6 Identities = 27/118 (22%), Positives = 43/118 (36%), Gaps = 19/118 (16%) Query: 48 DGCGCCK------VCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCE 101 D C C+ +C + C Q C KG A+ + + R C Sbjct: 44 DSCQSCRCHGDIVICKPAV---CRNPQ-CAFEKGEVLQIAANQCCPECVLRTPGS---CH 96 Query: 102 YNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKV-TGQCC 158 + +I+++G + + C+C G V C P P L C + L + G CC Sbjct: 97 HEKKIHEHGTEWASSPCSVCSCNHGEVRCTP-----QPCPPLSCGHQELAFIPEGSCC 149 Score = 30.8 bits (68), Expect = 2.1 Identities = 33/144 (22%), Positives = 48/144 (33%), Gaps = 17/144 (11%) Query: 27 PAACHCPLEAPKCAPGVGLVRD-----GCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFG 81 P C CP + + G V + C C E Q C L C G Sbjct: 209 PGKC-CPQCSARSCSAAGQVYEHGEQWSENACTTCICDRGEVRCHKQAC---LPLRCGKG 264 Query: 82 ASSTALKGICRAQ--SEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELS 139 S G C + S C Y+ + E ++ + C C G V C Q Sbjct: 265 QSRARRHGQCCEECVSPAGSCSYDGVVRYQDEMWKGSACEFCMCDHGQVTC-----QTGE 319 Query: 140 LPNLGCP-NPRLVKVTGQCCEEWV 162 + C + L+ + G+CC E + Sbjct: 320 CAKVECARDEELIHLDGKCCPECI 343 >gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens] Length = 480 Score = 43.5 bits (101), Expect = 3e-04 Identities = 42/129 (32%), Positives = 55/129 (42%), Gaps = 25/129 (19%) Query: 4 RIARALALVVTLLHLTRLALS-------TCPAACHCP--LEAPKCAPGV-----GLVRDG 49 +I RA L + LL L A + + P A CP E +C P G RD Sbjct: 2 QIPRAALLPLLLLLLAAPASAQLSRAGRSAPLAAGCPDRCEPARCPPQPEHCEGGRARDA 61 Query: 50 CGCCKVCAKQLNEDCSKTQ-PCDHTKGLEC--NFG--ASST----ALKGICRAQSEGRPC 100 CGCC+VC C + PC +GL+C FG AS+T A G+C S C Sbjct: 62 CGCCEVCGAPEGAACGLQEGPCG--EGLQCVVPFGVPASATVRRRAQAGLCVCASSEPVC 119 Query: 101 EYNSRIYQN 109 ++ Y N Sbjct: 120 GSDANTYAN 128 >gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens] Length = 763 Score = 42.4 bits (98), Expect = 7e-04 Identities = 20/60 (33%), Positives = 36/60 (60%), Gaps = 8/60 (13%) Query: 105 RIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCD 164 ++Y++G+++ +C+ QC C++G V C P L+ PNL C +++ G+CC V D Sbjct: 654 KLYRSGDNWTHSCQ-QCRCLEGEVDCWP-----LTCPNLSCEYTAILE--GECCPRCVSD 705 Score = 37.7 bits (86), Expect = 0.017 Identities = 21/65 (32%), Positives = 37/65 (56%), Gaps = 9/65 (13%) Query: 98 RPCEYNSRIYQNGESFQP--NCKHQCTCIDGAVGCIPLCPQELSLPNLGC-PNPRLVKVT 154 + C+ + +Y++ +S+ +C++ CTC GAV C + +S P L C P+ V + Sbjct: 271 KTCQVSGLLYRDQDSWVDGDHCRN-CTCKSGAVEC-----RRMSCPPLNCSPDSLPVHIA 324 Query: 155 GQCCE 159 GQCC+ Sbjct: 325 GQCCK 329 >gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens] Length = 810 Score = 42.4 bits (98), Expect = 7e-04 Identities = 20/60 (33%), Positives = 36/60 (60%), Gaps = 8/60 (13%) Query: 105 RIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCD 164 ++Y++G+++ +C+ QC C++G V C P L+ PNL C +++ G+CC V D Sbjct: 701 KLYRSGDNWTHSCQ-QCRCLEGEVDCWP-----LTCPNLSCEYTAILE--GECCPRCVSD 752 Score = 37.7 bits (86), Expect = 0.017 Identities = 21/65 (32%), Positives = 37/65 (56%), Gaps = 9/65 (13%) Query: 98 RPCEYNSRIYQNGESFQP--NCKHQCTCIDGAVGCIPLCPQELSLPNLGC-PNPRLVKVT 154 + C+ + +Y++ +S+ +C++ CTC GAV C + +S P L C P+ V + Sbjct: 271 KTCQVSGLLYRDQDSWVDGDHCRN-CTCKSGAVEC-----RRMSCPPLNCSPDSLPVHIA 324 Query: 155 GQCCE 159 GQCC+ Sbjct: 325 GQCCK 329 >gi|223029476 NEL-like protein 2 isoform d [Homo sapiens] Length = 839 Score = 42.4 bits (98), Expect = 7e-04 Identities = 23/64 (35%), Positives = 32/64 (50%), Gaps = 7/64 (10%) Query: 98 RPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCP-NPRLVKVTGQ 156 R C Y+ ES+ CK+ CTC++G + C + L PN CP L V G+ Sbjct: 295 RTCTMKGTTYREFESWIDGCKN-CTCLNGTIQC-----ETLICPNPDCPLKSALAYVDGK 348 Query: 157 CCEE 160 CC+E Sbjct: 349 CCKE 352 Score = 35.0 bits (79), Expect = 0.11 Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 11/68 (16%) Query: 106 IYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWV--- 162 +Y +G+++ NC+ QC C+ G V C P L P++ C L + +CC V Sbjct: 731 LYNSGDTWVQNCQ-QCRCLQGEVDCWP-----LPCPDVECEFSILPE--NECCPRCVTDP 782 Query: 163 CDEDSIKD 170 C D+I++ Sbjct: 783 CQADTIRN 790 >gi|223029474 NEL-like protein 2 isoform c [Homo sapiens] Length = 815 Score = 42.4 bits (98), Expect = 7e-04 Identities = 23/64 (35%), Positives = 32/64 (50%), Gaps = 7/64 (10%) Query: 98 RPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCP-NPRLVKVTGQ 156 R C Y+ ES+ CK+ CTC++G + C + L PN CP L V G+ Sbjct: 271 RTCTMKGTTYREFESWIDGCKN-CTCLNGTIQC-----ETLICPNPDCPLKSALAYVDGK 324 Query: 157 CCEE 160 CC+E Sbjct: 325 CCKE 328 Score = 35.0 bits (79), Expect = 0.11 Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 11/68 (16%) Query: 106 IYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWV--- 162 +Y +G+++ NC+ QC C+ G V C P L P++ C L + +CC V Sbjct: 707 LYNSGDTWVQNCQ-QCRCLQGEVDCWP-----LPCPDVECEFSILPE--NECCPRCVTDP 758 Query: 163 CDEDSIKD 170 C D+I++ Sbjct: 759 CQADTIRN 766 >gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens] Length = 816 Score = 42.4 bits (98), Expect = 7e-04 Identities = 23/64 (35%), Positives = 32/64 (50%), Gaps = 7/64 (10%) Query: 98 RPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCP-NPRLVKVTGQ 156 R C Y+ ES+ CK+ CTC++G + C + L PN CP L V G+ Sbjct: 272 RTCTMKGTTYREFESWIDGCKN-CTCLNGTIQC-----ETLICPNPDCPLKSALAYVDGK 325 Query: 157 CCEE 160 CC+E Sbjct: 326 CCKE 329 Score = 35.0 bits (79), Expect = 0.11 Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 11/68 (16%) Query: 106 IYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWV--- 162 +Y +G+++ NC+ QC C+ G V C P L P++ C L + +CC V Sbjct: 708 LYNSGDTWVQNCQ-QCRCLQGEVDCWP-----LPCPDVECEFSILPE--NECCPRCVTDP 759 Query: 163 CDEDSIKD 170 C D+I++ Sbjct: 760 CQADTIRN 767 >gi|223029470 NEL-like protein 2 isoform a [Homo sapiens] Length = 866 Score = 42.4 bits (98), Expect = 7e-04 Identities = 23/64 (35%), Positives = 32/64 (50%), Gaps = 7/64 (10%) Query: 98 RPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCP-NPRLVKVTGQ 156 R C Y+ ES+ CK+ CTC++G + C + L PN CP L V G+ Sbjct: 322 RTCTMKGTTYREFESWIDGCKN-CTCLNGTIQC-----ETLICPNPDCPLKSALAYVDGK 375 Query: 157 CCEE 160 CC+E Sbjct: 376 CCKE 379 Score = 35.0 bits (79), Expect = 0.11 Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 11/68 (16%) Query: 106 IYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWV--- 162 +Y +G+++ NC+ QC C+ G V C P L P++ C L + +CC V Sbjct: 758 LYNSGDTWVQNCQ-QCRCLQGEVDCWP-----LPCPDVECEFSILPE--NECCPRCVTDP 809 Query: 163 CDEDSIKD 170 C D+I++ Sbjct: 810 CQADTIRN 817 >gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens] Length = 816 Score = 42.4 bits (98), Expect = 7e-04 Identities = 23/64 (35%), Positives = 32/64 (50%), Gaps = 7/64 (10%) Query: 98 RPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCP-NPRLVKVTGQ 156 R C Y+ ES+ CK+ CTC++G + C + L PN CP L V G+ Sbjct: 272 RTCTMKGTTYREFESWIDGCKN-CTCLNGTIQC-----ETLICPNPDCPLKSALAYVDGK 325 Query: 157 CCEE 160 CC+E Sbjct: 326 CCKE 329 Score = 35.0 bits (79), Expect = 0.11 Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 11/68 (16%) Query: 106 IYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWV--- 162 +Y +G+++ NC+ QC C+ G V C P L P++ C L + +CC V Sbjct: 708 LYNSGDTWVQNCQ-QCRCLQGEVDCWP-----LPCPDVECEFSILPE--NECCPRCVTDP 759 Query: 163 CDEDSIKD 170 C D+I++ Sbjct: 760 CQADTIRN 767 >gi|24308541 HtrA serine peptidase 4 precursor [Homo sapiens] Length = 476 Score = 42.4 bits (98), Expect = 7e-04 Identities = 25/59 (42%), Positives = 30/59 (50%), Gaps = 8/59 (13%) Query: 25 TCPAACH---CPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDC--SKTQPCDHTKGLEC 78 +CPA C CP P CA G V D C CC+VC E C ++ QPC GL+C Sbjct: 39 SCPAVCQPTRCPA-LPTCALGTTPVFDLCRCCRVCPAAEREVCGGAQGQPC--APGLQC 94 >gi|34147715 chordin-like 1 isoform 3 precursor [Homo sapiens] Length = 456 Score = 42.0 bits (97), Expect = 0.001 Identities = 30/79 (37%), Positives = 36/79 (45%), Gaps = 20/79 (25%) Query: 98 RPCEYNSRIYQNGESF---------QPNCKHQCTCIDGAVGC-IPLCPQELSLPNLGCPN 147 + CEYN YQ+GE F QPN QC+C +G V C + CP+ L C Sbjct: 113 KSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPK------LTCAF 166 Query: 148 PRLVKVTGQCCEEWVCDED 166 P V V CC VC D Sbjct: 167 P--VSVPDSCCR--VCRGD 181 Score = 32.3 bits (72), Expect = 0.73 Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 17/82 (20%) Query: 97 GRPCEYNSRIYQNGESFQPNCKH-------QCTCIDGAVGCIPLCPQELSLPN-LGCPNP 148 G+ C N + Y +GES+ PN + CTC C +++ PN C P Sbjct: 257 GQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQEC-----KKIHCPNRYPCKYP 311 Query: 149 RLVKVTGQCCEEWVCDEDSIKD 170 + K+ G+CC+ VC K+ Sbjct: 312 Q--KIDGKCCK--VCPGKKAKE 329 >gi|221316563 chordin-like 1 isoform 2 precursor [Homo sapiens] Length = 457 Score = 42.0 bits (97), Expect = 0.001 Identities = 30/79 (37%), Positives = 36/79 (45%), Gaps = 20/79 (25%) Query: 98 RPCEYNSRIYQNGESF---------QPNCKHQCTCIDGAVGC-IPLCPQELSLPNLGCPN 147 + CEYN YQ+GE F QPN QC+C +G V C + CP+ L C Sbjct: 113 KSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPK------LTCAF 166 Query: 148 PRLVKVTGQCCEEWVCDED 166 P V V CC VC D Sbjct: 167 P--VSVPDSCCR--VCRGD 181 Score = 33.9 bits (76), Expect = 0.25 Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 17/87 (19%) Query: 97 GRPCEYNSRIYQNGESFQPNCKH-------QCTCIDGAVGCIPLCPQELSLPN-LGCPNP 148 G+ C N + Y +GES+ PN + CTC C +++ PN C P Sbjct: 257 GQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQEC-----KKIHCPNRYPCKYP 311 Query: 149 RLVKVTGQCCEEWVCDEDSIKDPMEDQ 175 + K+ G+CC+ VC K+ + Q Sbjct: 312 Q--KIDGKCCK--VCPGKKAKEELPGQ 334 >gi|221316561 chordin-like 1 isoform 1 precursor [Homo sapiens] Length = 458 Score = 42.0 bits (97), Expect = 0.001 Identities = 30/79 (37%), Positives = 36/79 (45%), Gaps = 20/79 (25%) Query: 98 RPCEYNSRIYQNGESF---------QPNCKHQCTCIDGAVGC-IPLCPQELSLPNLGCPN 147 + CEYN YQ+GE F QPN QC+C +G V C + CP+ L C Sbjct: 114 KSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPK------LTCAF 167 Query: 148 PRLVKVTGQCCEEWVCDED 166 P V V CC VC D Sbjct: 168 P--VSVPDSCCR--VCRGD 182 Score = 33.9 bits (76), Expect = 0.25 Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 17/87 (19%) Query: 97 GRPCEYNSRIYQNGESFQPNCKH-------QCTCIDGAVGCIPLCPQELSLPN-LGCPNP 148 G+ C N + Y +GES+ PN + CTC C +++ PN C P Sbjct: 258 GQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQEC-----KKIHCPNRYPCKYP 312 Query: 149 RLVKVTGQCCEEWVCDEDSIKDPMEDQ 175 + K+ G+CC+ VC K+ + Q Sbjct: 313 Q--KIDGKCCK--VCPGKKAKEELPGQ 335 >gi|33598931 scavenger receptor class F, member 1 isoform 3 precursor [Homo sapiens] Length = 569 Score = 41.6 bits (96), Expect = 0.001 Identities = 42/144 (29%), Positives = 55/144 (38%), Gaps = 22/144 (15%) Query: 25 TCPAA---CHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSK-TQPCDHTKGLECNF 80 TCP C L P + GV CG CK NE CS T C+ C Sbjct: 238 TCPPGFRGARCELPCPAGSHGVQCAHS-CGRCKH-----NEPCSPDTGSCE-----SCEP 286 Query: 81 GASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVG--CIPLCPQEL 138 G + T + C + G CE ++GE+ +P+ H C G +G C CP Sbjct: 287 GWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGT 346 Query: 139 SLPNLGCPNPRLVK-----VTGQC 157 + G P V+ VTG C Sbjct: 347 FGEDCGSTCPTCVQGSCDTVTGDC 370 Score = 29.6 bits (65), Expect = 4.7 Identities = 27/104 (25%), Positives = 34/104 (32%), Gaps = 33/104 (31%) Query: 24 STCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGAS 83 STC C C A +C G C C +P G C+F Sbjct: 157 STCRRPCQCNTAAARCEQATG----ACVC---------------KP--GWWGRRCSF--- 192 Query: 84 STALKGICRAQSEGRPCEYNS-RIYQNGESFQPNCKHQCTCIDG 126 R G PCE +S R + P C+ QC C+ G Sbjct: 193 --------RCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRG 228 >gi|33598929 scavenger receptor class F, member 1 isoform 1 precursor [Homo sapiens] Length = 830 Score = 41.6 bits (96), Expect = 0.001 Identities = 42/144 (29%), Positives = 55/144 (38%), Gaps = 22/144 (15%) Query: 25 TCPAA---CHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSK-TQPCDHTKGLECNF 80 TCP C L P + GV CG CK NE CS T C+ C Sbjct: 238 TCPPGFRGARCELPCPAGSHGVQCAHS-CGRCKH-----NEPCSPDTGSCE-----SCEP 286 Query: 81 GASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVG--CIPLCPQEL 138 G + T + C + G CE ++GE+ +P+ H C G +G C CP Sbjct: 287 GWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGT 346 Query: 139 SLPNLGCPNPRLVK-----VTGQC 157 + G P V+ VTG C Sbjct: 347 FGEDCGSTCPTCVQGSCDTVTGDC 370 Score = 29.6 bits (65), Expect = 4.7 Identities = 27/104 (25%), Positives = 34/104 (32%), Gaps = 33/104 (31%) Query: 24 STCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGAS 83 STC C C A +C G C C +P G C+F Sbjct: 157 STCRRPCQCNTAAARCEQATG----ACVC---------------KP--GWWGRRCSF--- 192 Query: 84 STALKGICRAQSEGRPCEYNS-RIYQNGESFQPNCKHQCTCIDG 126 R G PCE +S R + P C+ QC C+ G Sbjct: 193 --------RCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRG 228 >gi|122937343 platelet endothelial aggregation receptor 1 [Homo sapiens] Length = 1037 Score = 41.2 bits (95), Expect = 0.002 Identities = 34/114 (29%), Positives = 45/114 (39%), Gaps = 18/114 (15%) Query: 25 TCPAACHCPLEAPKCAPGVGLVR-----DGCGCCKVCAK-QLNEDCSKTQPCDHTKGLEC 78 +C A+C C EA C+P G G C C K Q E C+ CDH+ G + Sbjct: 489 SCNASCQCAHEAV-CSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDP 547 Query: 79 NFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIP 132 G C+A G C + G NC + CTC +G C+P Sbjct: 548 VHGRCQ------CQAGWMGARCHLSCPEGLWG----VNCSNTCTCKNGGT-CLP 590 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.136 0.450 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,811,790 Number of Sequences: 37866 Number of extensions: 855937 Number of successful extensions: 2555 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 58 Number of HSP's successfully gapped in prelim test: 115 Number of HSP's that attempted gapping in prelim test: 2071 Number of HSP's gapped (non-prelim): 579 length of query: 381 length of database: 18,247,518 effective HSP length: 104 effective length of query: 277 effective length of database: 14,309,454 effective search space: 3963718758 effective search space used: 3963718758 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.