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Search of human proteins with 31542325
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31542325 peroxisomal carnitine O-octanoyltransferase isoform
2 [Homo sapiens]
(612 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31542325 peroxisomal carnitine O-octanoyltransferase isoform ... 1264 0.0
gi|221316602 peroxisomal carnitine O-octanoyltransferase isoform... 1249 0.0
gi|21618331 carnitine acetyltransferase precursor [Homo sapiens] 294 1e-79
gi|188595668 choline acetyltransferase isoform 1 [Homo sapiens] 261 1e-69
gi|218931226 choline acetyltransferase isoform 1 [Homo sapiens] 261 1e-69
gi|218931224 choline acetyltransferase isoform 3 [Homo sapiens] 261 1e-69
gi|218931221 choline acetyltransferase isoform 1 [Homo sapiens] 261 1e-69
gi|188595684 choline acetyltransferase isoform 1 [Homo sapiens] 261 1e-69
gi|188595672 choline acetyltransferase isoform 1 [Homo sapiens] 261 1e-69
gi|188595670 choline acetyltransferase isoform 2 [Homo sapiens] 261 1e-69
gi|73623030 carnitine palmitoyltransferase 1A liver isoform 1 [H... 244 2e-64
gi|73623028 carnitine palmitoyltransferase 1A liver isoform 2 [H... 239 4e-63
gi|4503023 carnitine O-palmitoyltransferase precursor [Homo sapi... 237 3e-62
gi|223468672 carnitine palmitoyltransferase 1B isoform a [Homo s... 226 5e-59
gi|23238254 carnitine palmitoyltransferase 1B isoform a [Homo sa... 226 5e-59
gi|223468678 carnitine palmitoyltransferase 1B isoform a [Homo s... 226 5e-59
gi|4758050 carnitine palmitoyltransferase 1B isoform a [Homo sap... 226 5e-59
gi|23238256 carnitine palmitoyltransferase 1B isoform a [Homo sa... 226 5e-59
gi|209862905 carnitine palmitoyltransferase 1C isoform 1 [Homo s... 214 2e-55
gi|22748777 carnitine palmitoyltransferase 1C isoform 2 [Homo sa... 213 4e-55
gi|223468670 carnitine palmitoyltransferase 1B isoform c [Homo s... 204 1e-52
gi|223468674 carnitine palmitoyltransferase 1B isoform d [Homo s... 127 3e-29
gi|58535453 CDK5 regulatory subunit associated protein 2 isoform... 36 0.091
gi|58535451 CDK5 regulatory subunit associated protein 2 isoform... 36 0.091
gi|237858621 polyamine modulated factor 1 binding protein 1 isof... 34 0.45
gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens] 33 0.59
gi|91208426 U5 snRNP-specific protein [Homo sapiens] 32 1.7
gi|132814467 glutamyl aminopeptidase [Homo sapiens] 32 2.2
gi|117968420 NUF2, NDC80 kinetochore complex component [Homo sap... 31 3.8
gi|117968353 NUF2, NDC80 kinetochore complex component [Homo sap... 31 3.8
>gi|31542325 peroxisomal carnitine O-octanoyltransferase isoform 2
[Homo sapiens]
Length = 612
Score = 1264 bits (3270), Expect = 0.0
Identities = 612/612 (100%), Positives = 612/612 (100%)
Query: 1 MENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQS 60
MENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQS
Sbjct: 1 MENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQS 60
Query: 61 GIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGT 120
GIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGT
Sbjct: 61 GIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGT 120
Query: 121 QLERGSITLWHNLNYWQLLRKEKVPVHKVGNTPLDMNQFRMLFSTCKVPGITRDSIMNYF 180
QLERGSITLWHNLNYWQLLRKEKVPVHKVGNTPLDMNQFRMLFSTCKVPGITRDSIMNYF
Sbjct: 121 QLERGSITLWHNLNYWQLLRKEKVPVHKVGNTPLDMNQFRMLFSTCKVPGITRDSIMNYF 180
Query: 181 RTESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTPPELLRQLTYIHKKCHSEPDGPGIAAL 240
RTESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTPPELLRQLTYIHKKCHSEPDGPGIAAL
Sbjct: 181 RTESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTPPELLRQLTYIHKKCHSEPDGPGIAAL 240
Query: 241 TSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIAAILIG 300
TSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIAAILIG
Sbjct: 241 TSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIAAILIG 300
Query: 301 DPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYVDEKIFQNEGRWKGSEKVR 360
DPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYVDEKIFQNEGRWKGSEKVR
Sbjct: 301 DPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYVDEKIFQNEGRWKGSEKVR 360
Query: 361 DIPLPEELIFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFI 420
DIPLPEELIFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFI
Sbjct: 361 DIPLPEELIFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFI 420
Query: 421 QLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQDPSVNLRERQ 480
QLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQDPSVNLRERQ
Sbjct: 421 QLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQDPSVNLRERQ 480
Query: 481 QKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVPELFTDPLFSKSGGGGNFV 540
QKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVPELFTDPLFSKSGGGGNFV
Sbjct: 481 QKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVPELFTDPLFSKSGGGGNFV 540
Query: 541 LSTSLVGYLRVQGVVVPMVHNGYGFFYHIRDDRFVVACSAWKSCPETDAEKLVQLTFCAF 600
LSTSLVGYLRVQGVVVPMVHNGYGFFYHIRDDRFVVACSAWKSCPETDAEKLVQLTFCAF
Sbjct: 541 LSTSLVGYLRVQGVVVPMVHNGYGFFYHIRDDRFVVACSAWKSCPETDAEKLVQLTFCAF 600
Query: 601 HDMIQLMNSTHL 612
HDMIQLMNSTHL
Sbjct: 601 HDMIQLMNSTHL 612
>gi|221316602 peroxisomal carnitine O-octanoyltransferase isoform 1
[Homo sapiens]
Length = 640
Score = 1249 bits (3231), Expect = 0.0
Identities = 612/640 (95%), Positives = 612/640 (95%), Gaps = 28/640 (4%)
Query: 1 MENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESV--------------------- 39
MENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESV
Sbjct: 1 MENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDL 60
Query: 40 -------KPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLD 92
KPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLD
Sbjct: 61 TREGIQVKPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLD 120
Query: 93 VRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKVPVHKVGNT 152
VRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKVPVHKVGNT
Sbjct: 121 VRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKVPVHKVGNT 180
Query: 153 PLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLV 212
PLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLV
Sbjct: 181 PLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLV 240
Query: 213 TPPELLRQLTYIHKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSS 272
TPPELLRQLTYIHKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSS
Sbjct: 241 TPPELLRQLTYIHKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSS 300
Query: 273 LLVYSMEDSSPHVTPEDYSEIIAAILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDA 332
LLVYSMEDSSPHVTPEDYSEIIAAILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDA
Sbjct: 301 LLVYSMEDSSPHVTPEDYSEIIAAILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDA 360
Query: 333 MIMVNISYYVDEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREAS 392
MIMVNISYYVDEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREAS
Sbjct: 361 MIMVNISYYVDEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREAS 420
Query: 393 DLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRT 452
DLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRT
Sbjct: 421 DLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRT 480
Query: 453 ETMRSCTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLL 512
ETMRSCTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLL
Sbjct: 481 ETMRSCTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLL 540
Query: 513 IAKEEGLPVPELFTDPLFSKSGGGGNFVLSTSLVGYLRVQGVVVPMVHNGYGFFYHIRDD 572
IAKEEGLPVPELFTDPLFSKSGGGGNFVLSTSLVGYLRVQGVVVPMVHNGYGFFYHIRDD
Sbjct: 541 IAKEEGLPVPELFTDPLFSKSGGGGNFVLSTSLVGYLRVQGVVVPMVHNGYGFFYHIRDD 600
Query: 573 RFVVACSAWKSCPETDAEKLVQLTFCAFHDMIQLMNSTHL 612
RFVVACSAWKSCPETDAEKLVQLTFCAFHDMIQLMNSTHL
Sbjct: 601 RFVVACSAWKSCPETDAEKLVQLTFCAFHDMIQLMNSTHL 640
>gi|21618331 carnitine acetyltransferase precursor [Homo sapiens]
Length = 626
Score = 294 bits (753), Expect = 1e-79
Identities = 200/609 (32%), Positives = 317/609 (52%), Gaps = 34/609 (5%)
Query: 16 YQDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQS--GIGEKLHQKLLER 73
+QD+LP LPVP L++SL YL++++P ++EE+ T+++V +FQ+ G+GE+L + L R
Sbjct: 31 HQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLERR 90
Query: 74 AKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNL 133
A+ NWL EWWL AYL R P V ++ P QL + + L
Sbjct: 91 ARKTENWLSEWWLKTAYLQYRQPV---VIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGVL 147
Query: 134 NYWQLLRKEKVPVHKVGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNHIV 193
++ ++ E +PV +G PL MNQ+ + S+C+VPG +D++ N+ +T+ + P HI
Sbjct: 148 DFKVMIDNETLPVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTK---KPPTHIT 204
Query: 194 VLCRGRAFVFDVIH-EGCLVTPPELLRQLTYIHKKCHSEPDGPGIAALTSEERTRWAKAR 252
V+ + F DV H +G +T ++ QL I P + LTS R WAKA
Sbjct: 205 VVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEP-VGILTSNHRNSWAKAY 263
Query: 253 EYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIAAILIG------DPTVRW 306
LI D N + IQ S+ ++ + P V+ + Y +A ++ + RW
Sbjct: 264 NTLIK-DKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRW 322
Query: 307 GDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYVDEKIFQNEGRWKGSEKVRD----I 362
DK+ I +G G +HA + +V + YV E K E VR +
Sbjct: 323 FDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYT-------KKPELVRSPMVPL 375
Query: 363 PLPEELIFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFIQL 422
P+P++L F + ++ +DI +AK DL I F FGK K++ L PD FIQ+
Sbjct: 376 PMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQM 435
Query: 423 ALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQDPSVNLRERQQK 482
ALQLAYYR++G YE+A R F+ GRT+T+RS +++++ + ++M D SV ++ +
Sbjct: 436 ALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVEL 495
Query: 483 MLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVPELFTDPLFSKSGGGGNFVLS 542
+ +A H G+ FDRHLLGL L A E+ + +P++F D ++ + +F LS
Sbjct: 496 LRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIA---MHFHLS 552
Query: 543 TSLVGYLRVQGVVV--PMVHNGYGFFYHIRDDRFVVACSAWKSCPETDAEKLVQLTFCAF 600
TS V + V+ P+V +GYG Y+ + + SA+ SC ET+A +L A
Sbjct: 553 TSQVP-AKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKAL 611
Query: 601 HDMIQLMNS 609
DM L+ S
Sbjct: 612 LDMRALLQS 620
>gi|188595668 choline acetyltransferase isoform 1 [Homo sapiens]
Length = 630
Score = 261 bits (668), Expect = 1e-69
Identities = 182/604 (30%), Positives = 299/604 (49%), Gaps = 24/604 (3%)
Query: 17 QDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQS--GIGEKLHQKLLERA 74
+ LP LPVP L+++L YL+ ++ ++E+++K++ IVQ+F + G+GE L QKLLER
Sbjct: 10 ESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLLERQ 69
Query: 75 KGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLN 134
+ NW+ E+WLN YL+ R+ +N + PA F P QL + + L+
Sbjct: 70 EKTANWVSEYWLNDMYLNNRLALPVN---SSPAVIFARQHFPGTDDQLRFAASLISGVLS 126
Query: 135 YWQLLRKEKVPVH----KVGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPN 190
Y LL +P ++ PL M Q+ LFS+ ++PG T+D+++ + S P
Sbjct: 127 YKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVA--QNSSIMPEPE 184
Query: 191 HIVVLCRGRAFVFDVIHEGCLVTPPELLRQLTYIHKKCHSEPDG-PGIAALTSEERTRWA 249
H++V C + FV DV+ ++ +L QL I K +E + P I LTS+ R+ WA
Sbjct: 185 HVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWA 244
Query: 250 KAREYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIAAILIG----DPTVR 305
+AR L+ D N L+ I+ + + + D+ V D + + G + R
Sbjct: 245 EARTVLVK-DSTNRDSLDMIERCICLVCL-DAPGGVELSDTHRALQLLHGGGYSKNGANR 302
Query: 306 WGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYVDEKIFQNEGRWKGSEKVRDIPLP 365
W DKS + +G G C+H+PFD +++V + ++ + + Q+ + ++ V ++P P
Sbjct: 303 WYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADSVSELPAP 362
Query: 366 EELIFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQ 425
L + ++ + + + R +L Y F ++GK K + PD FIQ+ALQ
Sbjct: 363 RRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQ 422
Query: 426 LAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQD--PSVNLRERQQKM 483
LA+YRLH YE+A R F GR + +RS T EA+ + +++ D +V E+ +
Sbjct: 423 LAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLLLL 482
Query: 484 LQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVPELFTDPLFSKSGGGGNFVLST 543
A G D HLL L +A+ +PE+F D + S FVLST
Sbjct: 483 KDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMS---NRFVLST 539
Query: 544 SLVGYLRVQGVVV-PMVHNGYGFFYHIRDDRFVVACSAWKSCPETDAEKLVQLTFCAFHD 602
S V P+V NGYG Y+ + + + S++ SC ET + K + + D
Sbjct: 540 SQVPTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLID 599
Query: 603 MIQL 606
M L
Sbjct: 600 MRDL 603
>gi|218931226 choline acetyltransferase isoform 1 [Homo sapiens]
Length = 630
Score = 261 bits (668), Expect = 1e-69
Identities = 182/604 (30%), Positives = 299/604 (49%), Gaps = 24/604 (3%)
Query: 17 QDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQS--GIGEKLHQKLLERA 74
+ LP LPVP L+++L YL+ ++ ++E+++K++ IVQ+F + G+GE L QKLLER
Sbjct: 10 ESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLLERQ 69
Query: 75 KGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLN 134
+ NW+ E+WLN YL+ R+ +N + PA F P QL + + L+
Sbjct: 70 EKTANWVSEYWLNDMYLNNRLALPVN---SSPAVIFARQHFPGTDDQLRFAASLISGVLS 126
Query: 135 YWQLLRKEKVPVH----KVGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPN 190
Y LL +P ++ PL M Q+ LFS+ ++PG T+D+++ + S P
Sbjct: 127 YKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVA--QNSSIMPEPE 184
Query: 191 HIVVLCRGRAFVFDVIHEGCLVTPPELLRQLTYIHKKCHSEPDG-PGIAALTSEERTRWA 249
H++V C + FV DV+ ++ +L QL I K +E + P I LTS+ R+ WA
Sbjct: 185 HVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWA 244
Query: 250 KAREYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIAAILIG----DPTVR 305
+AR L+ D N L+ I+ + + + D+ V D + + G + R
Sbjct: 245 EARTVLVK-DSTNRDSLDMIERCICLVCL-DAPGGVELSDTHRALQLLHGGGYSKNGANR 302
Query: 306 WGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYVDEKIFQNEGRWKGSEKVRDIPLP 365
W DKS + +G G C+H+PFD +++V + ++ + + Q+ + ++ V ++P P
Sbjct: 303 WYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADSVSELPAP 362
Query: 366 EELIFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQ 425
L + ++ + + + R +L Y F ++GK K + PD FIQ+ALQ
Sbjct: 363 RRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQ 422
Query: 426 LAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQD--PSVNLRERQQKM 483
LA+YRLH YE+A R F GR + +RS T EA+ + +++ D +V E+ +
Sbjct: 423 LAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLLLL 482
Query: 484 LQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVPELFTDPLFSKSGGGGNFVLST 543
A G D HLL L +A+ +PE+F D + S FVLST
Sbjct: 483 KDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMS---NRFVLST 539
Query: 544 SLVGYLRVQGVVV-PMVHNGYGFFYHIRDDRFVVACSAWKSCPETDAEKLVQLTFCAFHD 602
S V P+V NGYG Y+ + + + S++ SC ET + K + + D
Sbjct: 540 SQVPTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLID 599
Query: 603 MIQL 606
M L
Sbjct: 600 MRDL 603
>gi|218931224 choline acetyltransferase isoform 3 [Homo sapiens]
Length = 666
Score = 261 bits (668), Expect = 1e-69
Identities = 182/604 (30%), Positives = 299/604 (49%), Gaps = 24/604 (3%)
Query: 17 QDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQS--GIGEKLHQKLLERA 74
+ LP LPVP L+++L YL+ ++ ++E+++K++ IVQ+F + G+GE L QKLLER
Sbjct: 46 ESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLLERQ 105
Query: 75 KGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLN 134
+ NW+ E+WLN YL+ R+ +N + PA F P QL + + L+
Sbjct: 106 EKTANWVSEYWLNDMYLNNRLALPVN---SSPAVIFARQHFPGTDDQLRFAASLISGVLS 162
Query: 135 YWQLLRKEKVPVH----KVGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPN 190
Y LL +P ++ PL M Q+ LFS+ ++PG T+D+++ + S P
Sbjct: 163 YKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVA--QNSSIMPEPE 220
Query: 191 HIVVLCRGRAFVFDVIHEGCLVTPPELLRQLTYIHKKCHSEPDG-PGIAALTSEERTRWA 249
H++V C + FV DV+ ++ +L QL I K +E + P I LTS+ R+ WA
Sbjct: 221 HVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWA 280
Query: 250 KAREYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIAAILIG----DPTVR 305
+AR L+ D N L+ I+ + + + D+ V D + + G + R
Sbjct: 281 EARTVLVK-DSTNRDSLDMIERCICLVCL-DAPGGVELSDTHRALQLLHGGGYSKNGANR 338
Query: 306 WGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYVDEKIFQNEGRWKGSEKVRDIPLP 365
W DKS + +G G C+H+PFD +++V + ++ + + Q+ + ++ V ++P P
Sbjct: 339 WYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADSVSELPAP 398
Query: 366 EELIFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQ 425
L + ++ + + + R +L Y F ++GK K + PD FIQ+ALQ
Sbjct: 399 RRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQ 458
Query: 426 LAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQD--PSVNLRERQQKM 483
LA+YRLH YE+A R F GR + +RS T EA+ + +++ D +V E+ +
Sbjct: 459 LAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLLLL 518
Query: 484 LQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVPELFTDPLFSKSGGGGNFVLST 543
A G D HLL L +A+ +PE+F D + S FVLST
Sbjct: 519 KDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMS---NRFVLST 575
Query: 544 SLVGYLRVQGVVV-PMVHNGYGFFYHIRDDRFVVACSAWKSCPETDAEKLVQLTFCAFHD 602
S V P+V NGYG Y+ + + + S++ SC ET + K + + D
Sbjct: 576 SQVPTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLID 635
Query: 603 MIQL 606
M L
Sbjct: 636 MRDL 639
>gi|218931221 choline acetyltransferase isoform 1 [Homo sapiens]
Length = 630
Score = 261 bits (668), Expect = 1e-69
Identities = 182/604 (30%), Positives = 299/604 (49%), Gaps = 24/604 (3%)
Query: 17 QDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQS--GIGEKLHQKLLERA 74
+ LP LPVP L+++L YL+ ++ ++E+++K++ IVQ+F + G+GE L QKLLER
Sbjct: 10 ESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLLERQ 69
Query: 75 KGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLN 134
+ NW+ E+WLN YL+ R+ +N + PA F P QL + + L+
Sbjct: 70 EKTANWVSEYWLNDMYLNNRLALPVN---SSPAVIFARQHFPGTDDQLRFAASLISGVLS 126
Query: 135 YWQLLRKEKVPVH----KVGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPN 190
Y LL +P ++ PL M Q+ LFS+ ++PG T+D+++ + S P
Sbjct: 127 YKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVA--QNSSIMPEPE 184
Query: 191 HIVVLCRGRAFVFDVIHEGCLVTPPELLRQLTYIHKKCHSEPDG-PGIAALTSEERTRWA 249
H++V C + FV DV+ ++ +L QL I K +E + P I LTS+ R+ WA
Sbjct: 185 HVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWA 244
Query: 250 KAREYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIAAILIG----DPTVR 305
+AR L+ D N L+ I+ + + + D+ V D + + G + R
Sbjct: 245 EARTVLVK-DSTNRDSLDMIERCICLVCL-DAPGGVELSDTHRALQLLHGGGYSKNGANR 302
Query: 306 WGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYVDEKIFQNEGRWKGSEKVRDIPLP 365
W DKS + +G G C+H+PFD +++V + ++ + + Q+ + ++ V ++P P
Sbjct: 303 WYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADSVSELPAP 362
Query: 366 EELIFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQ 425
L + ++ + + + R +L Y F ++GK K + PD FIQ+ALQ
Sbjct: 363 RRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQ 422
Query: 426 LAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQD--PSVNLRERQQKM 483
LA+YRLH YE+A R F GR + +RS T EA+ + +++ D +V E+ +
Sbjct: 423 LAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLLLL 482
Query: 484 LQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVPELFTDPLFSKSGGGGNFVLST 543
A G D HLL L +A+ +PE+F D + S FVLST
Sbjct: 483 KDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMS---NRFVLST 539
Query: 544 SLVGYLRVQGVVV-PMVHNGYGFFYHIRDDRFVVACSAWKSCPETDAEKLVQLTFCAFHD 602
S V P+V NGYG Y+ + + + S++ SC ET + K + + D
Sbjct: 540 SQVPTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLID 599
Query: 603 MIQL 606
M L
Sbjct: 600 MRDL 603
>gi|188595684 choline acetyltransferase isoform 1 [Homo sapiens]
Length = 630
Score = 261 bits (668), Expect = 1e-69
Identities = 182/604 (30%), Positives = 299/604 (49%), Gaps = 24/604 (3%)
Query: 17 QDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQS--GIGEKLHQKLLERA 74
+ LP LPVP L+++L YL+ ++ ++E+++K++ IVQ+F + G+GE L QKLLER
Sbjct: 10 ESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLLERQ 69
Query: 75 KGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLN 134
+ NW+ E+WLN YL+ R+ +N + PA F P QL + + L+
Sbjct: 70 EKTANWVSEYWLNDMYLNNRLALPVN---SSPAVIFARQHFPGTDDQLRFAASLISGVLS 126
Query: 135 YWQLLRKEKVPVH----KVGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPN 190
Y LL +P ++ PL M Q+ LFS+ ++PG T+D+++ + S P
Sbjct: 127 YKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVA--QNSSIMPEPE 184
Query: 191 HIVVLCRGRAFVFDVIHEGCLVTPPELLRQLTYIHKKCHSEPDG-PGIAALTSEERTRWA 249
H++V C + FV DV+ ++ +L QL I K +E + P I LTS+ R+ WA
Sbjct: 185 HVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWA 244
Query: 250 KAREYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIAAILIG----DPTVR 305
+AR L+ D N L+ I+ + + + D+ V D + + G + R
Sbjct: 245 EARTVLVK-DSTNRDSLDMIERCICLVCL-DAPGGVELSDTHRALQLLHGGGYSKNGANR 302
Query: 306 WGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYVDEKIFQNEGRWKGSEKVRDIPLP 365
W DKS + +G G C+H+PFD +++V + ++ + + Q+ + ++ V ++P P
Sbjct: 303 WYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADSVSELPAP 362
Query: 366 EELIFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQ 425
L + ++ + + + R +L Y F ++GK K + PD FIQ+ALQ
Sbjct: 363 RRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQ 422
Query: 426 LAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQD--PSVNLRERQQKM 483
LA+YRLH YE+A R F GR + +RS T EA+ + +++ D +V E+ +
Sbjct: 423 LAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLLLL 482
Query: 484 LQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVPELFTDPLFSKSGGGGNFVLST 543
A G D HLL L +A+ +PE+F D + S FVLST
Sbjct: 483 KDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMS---NRFVLST 539
Query: 544 SLVGYLRVQGVVV-PMVHNGYGFFYHIRDDRFVVACSAWKSCPETDAEKLVQLTFCAFHD 602
S V P+V NGYG Y+ + + + S++ SC ET + K + + D
Sbjct: 540 SQVPTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLID 599
Query: 603 MIQL 606
M L
Sbjct: 600 MRDL 603
>gi|188595672 choline acetyltransferase isoform 1 [Homo sapiens]
Length = 630
Score = 261 bits (668), Expect = 1e-69
Identities = 182/604 (30%), Positives = 299/604 (49%), Gaps = 24/604 (3%)
Query: 17 QDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQS--GIGEKLHQKLLERA 74
+ LP LPVP L+++L YL+ ++ ++E+++K++ IVQ+F + G+GE L QKLLER
Sbjct: 10 ESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLLERQ 69
Query: 75 KGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLN 134
+ NW+ E+WLN YL+ R+ +N + PA F P QL + + L+
Sbjct: 70 EKTANWVSEYWLNDMYLNNRLALPVN---SSPAVIFARQHFPGTDDQLRFAASLISGVLS 126
Query: 135 YWQLLRKEKVPVH----KVGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPN 190
Y LL +P ++ PL M Q+ LFS+ ++PG T+D+++ + S P
Sbjct: 127 YKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVA--QNSSIMPEPE 184
Query: 191 HIVVLCRGRAFVFDVIHEGCLVTPPELLRQLTYIHKKCHSEPDG-PGIAALTSEERTRWA 249
H++V C + FV DV+ ++ +L QL I K +E + P I LTS+ R+ WA
Sbjct: 185 HVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWA 244
Query: 250 KAREYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIAAILIG----DPTVR 305
+AR L+ D N L+ I+ + + + D+ V D + + G + R
Sbjct: 245 EARTVLVK-DSTNRDSLDMIERCICLVCL-DAPGGVELSDTHRALQLLHGGGYSKNGANR 302
Query: 306 WGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYVDEKIFQNEGRWKGSEKVRDIPLP 365
W DKS + +G G C+H+PFD +++V + ++ + + Q+ + ++ V ++P P
Sbjct: 303 WYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADSVSELPAP 362
Query: 366 EELIFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQ 425
L + ++ + + + R +L Y F ++GK K + PD FIQ+ALQ
Sbjct: 363 RRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQ 422
Query: 426 LAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQD--PSVNLRERQQKM 483
LA+YRLH YE+A R F GR + +RS T EA+ + +++ D +V E+ +
Sbjct: 423 LAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLLLL 482
Query: 484 LQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVPELFTDPLFSKSGGGGNFVLST 543
A G D HLL L +A+ +PE+F D + S FVLST
Sbjct: 483 KDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMS---NRFVLST 539
Query: 544 SLVGYLRVQGVVV-PMVHNGYGFFYHIRDDRFVVACSAWKSCPETDAEKLVQLTFCAFHD 602
S V P+V NGYG Y+ + + + S++ SC ET + K + + D
Sbjct: 540 SQVPTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLID 599
Query: 603 MIQL 606
M L
Sbjct: 600 MRDL 603
>gi|188595670 choline acetyltransferase isoform 2 [Homo sapiens]
Length = 748
Score = 261 bits (668), Expect = 1e-69
Identities = 182/604 (30%), Positives = 299/604 (49%), Gaps = 24/604 (3%)
Query: 17 QDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQS--GIGEKLHQKLLERA 74
+ LP LPVP L+++L YL+ ++ ++E+++K++ IVQ+F + G+GE L QKLLER
Sbjct: 128 ESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLLERQ 187
Query: 75 KGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLN 134
+ NW+ E+WLN YL+ R+ +N + PA F P QL + + L+
Sbjct: 188 EKTANWVSEYWLNDMYLNNRLALPVN---SSPAVIFARQHFPGTDDQLRFAASLISGVLS 244
Query: 135 YWQLLRKEKVPVH----KVGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPN 190
Y LL +P ++ PL M Q+ LFS+ ++PG T+D+++ + S P
Sbjct: 245 YKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVA--QNSSIMPEPE 302
Query: 191 HIVVLCRGRAFVFDVIHEGCLVTPPELLRQLTYIHKKCHSEPDG-PGIAALTSEERTRWA 249
H++V C + FV DV+ ++ +L QL I K +E + P I LTS+ R+ WA
Sbjct: 303 HVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWA 362
Query: 250 KAREYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIAAILIG----DPTVR 305
+AR L+ D N L+ I+ + + + D+ V D + + G + R
Sbjct: 363 EARTVLVK-DSTNRDSLDMIERCICLVCL-DAPGGVELSDTHRALQLLHGGGYSKNGANR 420
Query: 306 WGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYVDEKIFQNEGRWKGSEKVRDIPLP 365
W DKS + +G G C+H+PFD +++V + ++ + + Q+ + ++ V ++P P
Sbjct: 421 WYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADSVSELPAP 480
Query: 366 EELIFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQ 425
L + ++ + + + R +L Y F ++GK K + PD FIQ+ALQ
Sbjct: 481 RRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQ 540
Query: 426 LAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQD--PSVNLRERQQKM 483
LA+YRLH YE+A R F GR + +RS T EA+ + +++ D +V E+ +
Sbjct: 541 LAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLLLL 600
Query: 484 LQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVPELFTDPLFSKSGGGGNFVLST 543
A G D HLL L +A+ +PE+F D + S FVLST
Sbjct: 601 KDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMS---NRFVLST 657
Query: 544 SLVGYLRVQGVVV-PMVHNGYGFFYHIRDDRFVVACSAWKSCPETDAEKLVQLTFCAFHD 602
S V P+V NGYG Y+ + + + S++ SC ET + K + + D
Sbjct: 658 SQVPTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLID 717
Query: 603 MIQL 606
M L
Sbjct: 718 MRDL 721
>gi|73623030 carnitine palmitoyltransferase 1A liver isoform 1 [Homo
sapiens]
Length = 773
Score = 244 bits (623), Expect = 2e-64
Identities = 182/613 (29%), Positives = 300/613 (48%), Gaps = 33/613 (5%)
Query: 14 FQYQDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLER 73
+ +Q SLP LPVP++++++ +YL+SV+P +E++K+ + Q F G+G +L L +
Sbjct: 165 YSFQTSLPRLPVPAVKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLK 224
Query: 74 AKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNL 133
+ N++ +WW YL R P +N N+ A + P Q R + L
Sbjct: 225 SWWATNYVSDWWEEYIYLRGRGPLMVNSNYY--AMDLLYILPTH--IQAARAGNAIHAIL 280
Query: 134 NYWQLLRKEKV-PVHKVGNT-PLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNH 191
Y + L +E++ P+ +G+T PL Q+ +F+T ++PG D+I + R H
Sbjct: 281 LYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHM-------RDSKH 333
Query: 192 IVVLCRGRAFVFDVIHEGCLVTPPELLRQLTYI-HKKCHSEPDGPGIAALTSEERTRWAK 250
IVV RGR F + H+G L+ P E+ +Q+ I +P +AALT+ +R WA+
Sbjct: 334 IVVYHRGRYFKVWLYHDGRLLKPREMEQQMQRILDNTSEPQPGEARLAALTAGDRVPWAR 393
Query: 251 AREYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPED----YSEIIAAILIGDPTVRW 306
R+ G +N L+ ++ + +++++ ED ++L G RW
Sbjct: 394 CRQAYFGRG-KNKQSLDAVEKAAFFVTLDETEEGYRSEDPDTSMDSYAKSLLHGRCYDRW 452
Query: 307 GDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYVD-----EKIFQNEGRWKGSEKVRD 361
DKS+ + F NG G N +H+ DA I+ ++ YV + + +G KG +
Sbjct: 453 FDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINP-N 511
Query: 362 IPLPEELIFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFIQ 421
IP P L + + + I + A+D+ ++ F +FGK + K PD F+Q
Sbjct: 512 IPYPTRLQWDIPGECQEVIETSLNTANLLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQ 571
Query: 422 LALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQDPSVNLRERQQ 481
LALQLA+Y+ G YE +MTR F GRTET+RSCT E+ + ++M DP+ + +R +
Sbjct: 572 LALQLAHYKDMGKFCLTYEASMTRLFREGRTETVRSCTTESCDFVRAMVDPAQTVEQRLK 631
Query: 482 KMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVP---ELFTDP-LFSKSGGGG 537
A KH M + G G DRHL L +++K + P E+ ++P S S
Sbjct: 632 LFKLASEKHQHMYRLAMTGSGIDRHLFCLYVVSKYLAVESPFLKEVLSEPWRLSTSQTPQ 691
Query: 538 NFVLSTSLVG---YLRVQGVVVPMVHNGYGFFYHIRDDRFV-VACSAWKSCPETDAEKLV 593
V L Y+ G P+ +GYG Y + + + S+ SCPETD+ +
Sbjct: 692 QQVELFDLENNPEYVSSGGGFGPVADDGYGVSYILVGENLINFHISSKFSCPETDSHRFG 751
Query: 594 QLTFCAFHDMIQL 606
+ A D+I L
Sbjct: 752 RHLKEAMTDIITL 764
>gi|73623028 carnitine palmitoyltransferase 1A liver isoform 2 [Homo
sapiens]
Length = 756
Score = 239 bits (611), Expect = 4e-63
Identities = 177/594 (29%), Positives = 291/594 (48%), Gaps = 33/594 (5%)
Query: 14 FQYQDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLER 73
+ +Q SLP LPVP++++++ +YL+SV+P +E++K+ + Q F G+G +L L +
Sbjct: 165 YSFQTSLPRLPVPAVKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLK 224
Query: 74 AKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNL 133
+ N++ +WW YL R P +N N+ A + P Q R + L
Sbjct: 225 SWWATNYVSDWWEEYIYLRGRGPLMVNSNYY--AMDLLYILPTH--IQAARAGNAIHAIL 280
Query: 134 NYWQLLRKEKV-PVHKVGNT-PLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNH 191
Y + L +E++ P+ +G+T PL Q+ +F+T ++PG D+I + R H
Sbjct: 281 LYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHM-------RDSKH 333
Query: 192 IVVLCRGRAFVFDVIHEGCLVTPPELLRQLTYI-HKKCHSEPDGPGIAALTSEERTRWAK 250
IVV RGR F + H+G L+ P E+ +Q+ I +P +AALT+ +R WA+
Sbjct: 334 IVVYHRGRYFKVWLYHDGRLLKPREMEQQMQRILDNTSEPQPGEARLAALTAGDRVPWAR 393
Query: 251 AREYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPED----YSEIIAAILIGDPTVRW 306
R+ G +N L+ ++ + +++++ ED ++L G RW
Sbjct: 394 CRQAYFGRG-KNKQSLDAVEKAAFFVTLDETEEGYRSEDPDTSMDSYAKSLLHGRCYDRW 452
Query: 307 GDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYVD-----EKIFQNEGRWKGSEKVRD 361
DKS+ + F NG G N +H+ DA I+ ++ YV + + +G KG +
Sbjct: 453 FDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINP-N 511
Query: 362 IPLPEELIFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFIQ 421
IP P L + + + I + A+D+ ++ F +FGK + K PD F+Q
Sbjct: 512 IPYPTRLQWDIPGECQEVIETSLNTANLLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQ 571
Query: 422 LALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQDPSVNLRERQQ 481
LALQLA+Y+ G YE +MTR F GRTET+RSCT E+ + ++M DP+ + +R +
Sbjct: 572 LALQLAHYKDMGKFCLTYEASMTRLFREGRTETVRSCTTESCDFVRAMVDPAQTVEQRLK 631
Query: 482 KMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVP---ELFTDP-LFSKSGGGG 537
A KH M + G G DRHL L +++K + P E+ ++P S S
Sbjct: 632 LFKLASEKHQHMYRLAMTGSGIDRHLFCLYVVSKYLAVESPFLKEVLSEPWRLSTSQTPQ 691
Query: 538 NFVLSTSLVG---YLRVQGVVVPMVHNGYGFFYHIRDDRFV-VACSAWKSCPET 587
V L Y+ G P+ +GYG Y + + + S+ SCPET
Sbjct: 692 QQVELFDLENNPEYVSSGGGFGPVADDGYGVSYILVGENLINFHISSKFSCPET 745
>gi|4503023 carnitine O-palmitoyltransferase precursor [Homo
sapiens]
Length = 658
Score = 237 bits (604), Expect = 3e-62
Identities = 186/634 (29%), Positives = 307/634 (48%), Gaps = 63/634 (9%)
Query: 13 TFQYQDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQSGIGEKLHQKL-- 70
T YQDSLP LP+P LE+++++YL + KP N +++KTE+ + F++GIG++LH++L
Sbjct: 42 TMHYQDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHEQLVA 101
Query: 71 LERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLW 130
L++ +++ W ++ YL R LN N P F + QL R +
Sbjct: 102 LDKQNKHTSYISGPWFDM-YLSARDSVVLNFN---PFMAFNPDPKSEYNDQLTRATNMTV 157
Query: 131 HNLNYWQLLRK------------------------EKVP-------VHKVGNTPLDMNQF 159
+ + + LR VP + V PLDM+Q+
Sbjct: 158 SAIRFLKTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQY 217
Query: 160 RMLFSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVI-HEGCLVTPPELL 218
LF++ ++P +RD + T+ + R H++VL +G ++FDV+ +G +V+P E+
Sbjct: 218 FRLFNSTRLPKPSRDELF----TDDKAR---HLLVLRKGNFYIFDVLDQDGNIVSPSEIQ 270
Query: 219 RQLTYIHKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSM 278
L YI P+ P +A LTSE R WA+ R+ L+ E L K+ S++ +
Sbjct: 271 AHLKYILSDSSPAPEFP-LAYLTSENRDIWAELRQKLMSSGNEES--LRKVDSAVFCLCL 327
Query: 279 EDSSPHVTPEDYSEIIAAILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNI 338
+D +D + +L GD T RW DKS+NLI +G + +H+ D + ++
Sbjct: 328 DD----FPIKDLVHLSHNMLHGDGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRF 383
Query: 339 SYYVDEKIFQNEGRWKGSEKVR--DIPLPEELIFIVDEKVLNDINQAKAQYLREASDLQI 396
V + Q S+ ++L F + + + I AK ++ L I
Sbjct: 384 FNEVFKDSTQTPAVTPQSQPATTDSTVTVQKLNFELTDALKTGITAAKEKFDATMKTLTI 443
Query: 397 AAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMR 456
F GK+ K + L PD QLA Q+A+ R +G YE+ T F HGRTET+R
Sbjct: 444 DCVQFQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIR 503
Query: 457 SCTVEAVRWCQS-MQDPS-VNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIA 514
+V R ++ +++PS + E QQ M++ H ++ K+ + G+GFDRHL L +A
Sbjct: 504 PASVYTKRCSEAFVREPSRHSAGELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHLA 563
Query: 515 KEEGLPVPELFTDPLFSKSGGGGNFVLSTSLVGYLRVQ-GVVVPMVHNGYGFFYHIRDDR 573
+G+ +PEL+ DP + G + VLSTS + V G P+V +G+G Y + D+
Sbjct: 564 AAKGIILPELYLDPAY---GQINHNVLSTSTLSSPAVNLGGFAPVVSDGFGVGYAVHDN- 619
Query: 574 FVVACSAWKSCPETDAEKLVQLTFCAFHDMIQLM 607
+ C+ S P +A + +Q A DM +
Sbjct: 620 -WIGCNV-SSYPGRNAREFLQCVEKALEDMFDAL 651
>gi|223468672 carnitine palmitoyltransferase 1B isoform a [Homo
sapiens]
Length = 772
Score = 226 bits (576), Expect = 5e-59
Identities = 181/618 (29%), Positives = 288/618 (46%), Gaps = 55/618 (8%)
Query: 4 QLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQSGIG 63
+L S + +Q SLP LPVP + ++++YLESV+P + EEY + E + ++FQ
Sbjct: 157 RLLSSRHPMLYSFQTSLPKLPVPRVSATIQRYLESVRPLLDDEEYYRMELLAKEFQDKTA 216
Query: 64 EKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGTQLE 123
+L + L+ ++ N++ +WW YL R P +N N+ + Q
Sbjct: 217 PRLQKYLVLKSWWASNYVSDWWEEYIYLRGRSPLMVNSNYYV----MDLVLIKNTDVQAA 272
Query: 124 RGSITLWHNLNYWQLLRKEKV-PVHKVGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFRT 182
R + + Y + L +E++ PV +G P+ Q +F+T ++PG D + +
Sbjct: 273 RLGNIIHAMIMYRRKLDREEIKPVMALGIVPMCSYQMERMFNTTRIPGKDTDVLQHL--- 329
Query: 183 ESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTPPELLRQLTYIHKKCHSEPDGPG---IAA 239
S+ R H+ V +GR F + L+ P +L Q I P PG +AA
Sbjct: 330 -SDSR---HVAVYHKGRFFKLWLYEGARLLKPQDLEMQFQRILDD--PSPPQPGEEKLAA 383
Query: 240 LTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIA---A 296
LT+ R WA+AR+ +N A LE I+ + ++++ S PED + + A
Sbjct: 384 LTAGGRVEWAQARQAFFS-SGKNKAALEAIERAAFFVALDEESYSYDPEDEASLSLYGKA 442
Query: 297 ILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYV-----DEKIFQNEG 351
+L G+ RW DKS+ LISF NG G N +HA DA I+ ++ +V + G
Sbjct: 443 LLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTDSFHLGYTETG 502
Query: 352 RWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTKN 411
G P P L + + ++ I + A D+++ + F FGK L K
Sbjct: 503 HCLGKPNPALAP-PTRLQWDIPKQCQAVIESSYQVAKALADDVELYCFQFLPFGKGLIKK 561
Query: 412 KMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQD 471
PD F+Q+ALQLA++R G YE +MTR F GRTET+RSCT E+ + Q+M +
Sbjct: 562 CRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTRMFREGRTETVRSCTSESTAFVQAMME 621
Query: 472 PSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVP---ELFTDP 528
S + + +A KH M + G G DRHL L L++K G+ P E+ ++P
Sbjct: 622 GSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDRHLFCLYLVSKYLGVSSPFLAEVLSEP 681
Query: 529 LFSKSGGGGNFVLSTSLV--------------GYLRVQGVVVPMVHNGYGFFYHIRDDRF 574
+ LSTS + +L G P+ +GYG Y I +
Sbjct: 682 ----------WRLSTSQIPQSQIRMFDPEQHPNHLGAGGGFGPVADDGYGVSYMIAGENT 731
Query: 575 V-VACSAWKSCPETDAEK 591
+ S+ S ET+A++
Sbjct: 732 IFFHISSKFSSSETNAQR 749
>gi|23238254 carnitine palmitoyltransferase 1B isoform a [Homo
sapiens]
Length = 772
Score = 226 bits (576), Expect = 5e-59
Identities = 181/618 (29%), Positives = 288/618 (46%), Gaps = 55/618 (8%)
Query: 4 QLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQSGIG 63
+L S + +Q SLP LPVP + ++++YLESV+P + EEY + E + ++FQ
Sbjct: 157 RLLSSRHPMLYSFQTSLPKLPVPRVSATIQRYLESVRPLLDDEEYYRMELLAKEFQDKTA 216
Query: 64 EKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGTQLE 123
+L + L+ ++ N++ +WW YL R P +N N+ + Q
Sbjct: 217 PRLQKYLVLKSWWASNYVSDWWEEYIYLRGRSPLMVNSNYYV----MDLVLIKNTDVQAA 272
Query: 124 RGSITLWHNLNYWQLLRKEKV-PVHKVGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFRT 182
R + + Y + L +E++ PV +G P+ Q +F+T ++PG D + +
Sbjct: 273 RLGNIIHAMIMYRRKLDREEIKPVMALGIVPMCSYQMERMFNTTRIPGKDTDVLQHL--- 329
Query: 183 ESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTPPELLRQLTYIHKKCHSEPDGPG---IAA 239
S+ R H+ V +GR F + L+ P +L Q I P PG +AA
Sbjct: 330 -SDSR---HVAVYHKGRFFKLWLYEGARLLKPQDLEMQFQRILDD--PSPPQPGEEKLAA 383
Query: 240 LTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIA---A 296
LT+ R WA+AR+ +N A LE I+ + ++++ S PED + + A
Sbjct: 384 LTAGGRVEWAQARQAFFS-SGKNKAALEAIERAAFFVALDEESYSYDPEDEASLSLYGKA 442
Query: 297 ILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYV-----DEKIFQNEG 351
+L G+ RW DKS+ LISF NG G N +HA DA I+ ++ +V + G
Sbjct: 443 LLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTDSFHLGYTETG 502
Query: 352 RWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTKN 411
G P P L + + ++ I + A D+++ + F FGK L K
Sbjct: 503 HCLGKPNPALAP-PTRLQWDIPKQCQAVIESSYQVAKALADDVELYCFQFLPFGKGLIKK 561
Query: 412 KMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQD 471
PD F+Q+ALQLA++R G YE +MTR F GRTET+RSCT E+ + Q+M +
Sbjct: 562 CRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTRMFREGRTETVRSCTSESTAFVQAMME 621
Query: 472 PSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVP---ELFTDP 528
S + + +A KH M + G G DRHL L L++K G+ P E+ ++P
Sbjct: 622 GSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDRHLFCLYLVSKYLGVSSPFLAEVLSEP 681
Query: 529 LFSKSGGGGNFVLSTSLV--------------GYLRVQGVVVPMVHNGYGFFYHIRDDRF 574
+ LSTS + +L G P+ +GYG Y I +
Sbjct: 682 ----------WRLSTSQIPQSQIRMFDPEQHPNHLGAGGGFGPVADDGYGVSYMIAGENT 731
Query: 575 V-VACSAWKSCPETDAEK 591
+ S+ S ET+A++
Sbjct: 732 IFFHISSKFSSSETNAQR 749
>gi|223468678 carnitine palmitoyltransferase 1B isoform a [Homo
sapiens]
Length = 772
Score = 226 bits (576), Expect = 5e-59
Identities = 181/618 (29%), Positives = 288/618 (46%), Gaps = 55/618 (8%)
Query: 4 QLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQSGIG 63
+L S + +Q SLP LPVP + ++++YLESV+P + EEY + E + ++FQ
Sbjct: 157 RLLSSRHPMLYSFQTSLPKLPVPRVSATIQRYLESVRPLLDDEEYYRMELLAKEFQDKTA 216
Query: 64 EKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGTQLE 123
+L + L+ ++ N++ +WW YL R P +N N+ + Q
Sbjct: 217 PRLQKYLVLKSWWASNYVSDWWEEYIYLRGRSPLMVNSNYYV----MDLVLIKNTDVQAA 272
Query: 124 RGSITLWHNLNYWQLLRKEKV-PVHKVGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFRT 182
R + + Y + L +E++ PV +G P+ Q +F+T ++PG D + +
Sbjct: 273 RLGNIIHAMIMYRRKLDREEIKPVMALGIVPMCSYQMERMFNTTRIPGKDTDVLQHL--- 329
Query: 183 ESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTPPELLRQLTYIHKKCHSEPDGPG---IAA 239
S+ R H+ V +GR F + L+ P +L Q I P PG +AA
Sbjct: 330 -SDSR---HVAVYHKGRFFKLWLYEGARLLKPQDLEMQFQRILDD--PSPPQPGEEKLAA 383
Query: 240 LTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIA---A 296
LT+ R WA+AR+ +N A LE I+ + ++++ S PED + + A
Sbjct: 384 LTAGGRVEWAQARQAFFS-SGKNKAALEAIERAAFFVALDEESYSYDPEDEASLSLYGKA 442
Query: 297 ILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYV-----DEKIFQNEG 351
+L G+ RW DKS+ LISF NG G N +HA DA I+ ++ +V + G
Sbjct: 443 LLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTDSFHLGYTETG 502
Query: 352 RWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTKN 411
G P P L + + ++ I + A D+++ + F FGK L K
Sbjct: 503 HCLGKPNPALAP-PTRLQWDIPKQCQAVIESSYQVAKALADDVELYCFQFLPFGKGLIKK 561
Query: 412 KMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQD 471
PD F+Q+ALQLA++R G YE +MTR F GRTET+RSCT E+ + Q+M +
Sbjct: 562 CRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTRMFREGRTETVRSCTSESTAFVQAMME 621
Query: 472 PSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVP---ELFTDP 528
S + + +A KH M + G G DRHL L L++K G+ P E+ ++P
Sbjct: 622 GSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDRHLFCLYLVSKYLGVSSPFLAEVLSEP 681
Query: 529 LFSKSGGGGNFVLSTSLV--------------GYLRVQGVVVPMVHNGYGFFYHIRDDRF 574
+ LSTS + +L G P+ +GYG Y I +
Sbjct: 682 ----------WRLSTSQIPQSQIRMFDPEQHPNHLGAGGGFGPVADDGYGVSYMIAGENT 731
Query: 575 V-VACSAWKSCPETDAEK 591
+ S+ S ET+A++
Sbjct: 732 IFFHISSKFSSSETNAQR 749
>gi|4758050 carnitine palmitoyltransferase 1B isoform a [Homo
sapiens]
Length = 772
Score = 226 bits (576), Expect = 5e-59
Identities = 181/618 (29%), Positives = 288/618 (46%), Gaps = 55/618 (8%)
Query: 4 QLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQSGIG 63
+L S + +Q SLP LPVP + ++++YLESV+P + EEY + E + ++FQ
Sbjct: 157 RLLSSRHPMLYSFQTSLPKLPVPRVSATIQRYLESVRPLLDDEEYYRMELLAKEFQDKTA 216
Query: 64 EKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGTQLE 123
+L + L+ ++ N++ +WW YL R P +N N+ + Q
Sbjct: 217 PRLQKYLVLKSWWASNYVSDWWEEYIYLRGRSPLMVNSNYYV----MDLVLIKNTDVQAA 272
Query: 124 RGSITLWHNLNYWQLLRKEKV-PVHKVGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFRT 182
R + + Y + L +E++ PV +G P+ Q +F+T ++PG D + +
Sbjct: 273 RLGNIIHAMIMYRRKLDREEIKPVMALGIVPMCSYQMERMFNTTRIPGKDTDVLQHL--- 329
Query: 183 ESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTPPELLRQLTYIHKKCHSEPDGPG---IAA 239
S+ R H+ V +GR F + L+ P +L Q I P PG +AA
Sbjct: 330 -SDSR---HVAVYHKGRFFKLWLYEGARLLKPQDLEMQFQRILDD--PSPPQPGEEKLAA 383
Query: 240 LTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIA---A 296
LT+ R WA+AR+ +N A LE I+ + ++++ S PED + + A
Sbjct: 384 LTAGGRVEWAQARQAFFS-SGKNKAALEAIERAAFFVALDEESYSYDPEDEASLSLYGKA 442
Query: 297 ILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYV-----DEKIFQNEG 351
+L G+ RW DKS+ LISF NG G N +HA DA I+ ++ +V + G
Sbjct: 443 LLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTDSFHLGYTETG 502
Query: 352 RWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTKN 411
G P P L + + ++ I + A D+++ + F FGK L K
Sbjct: 503 HCLGKPNPALAP-PTRLQWDIPKQCQAVIESSYQVAKALADDVELYCFQFLPFGKGLIKK 561
Query: 412 KMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQD 471
PD F+Q+ALQLA++R G YE +MTR F GRTET+RSCT E+ + Q+M +
Sbjct: 562 CRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTRMFREGRTETVRSCTSESTAFVQAMME 621
Query: 472 PSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVP---ELFTDP 528
S + + +A KH M + G G DRHL L L++K G+ P E+ ++P
Sbjct: 622 GSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDRHLFCLYLVSKYLGVSSPFLAEVLSEP 681
Query: 529 LFSKSGGGGNFVLSTSLV--------------GYLRVQGVVVPMVHNGYGFFYHIRDDRF 574
+ LSTS + +L G P+ +GYG Y I +
Sbjct: 682 ----------WRLSTSQIPQSQIRMFDPEQHPNHLGAGGGFGPVADDGYGVSYMIAGENT 731
Query: 575 V-VACSAWKSCPETDAEK 591
+ S+ S ET+A++
Sbjct: 732 IFFHISSKFSSSETNAQR 749
>gi|23238256 carnitine palmitoyltransferase 1B isoform a [Homo
sapiens]
Length = 772
Score = 226 bits (576), Expect = 5e-59
Identities = 181/618 (29%), Positives = 288/618 (46%), Gaps = 55/618 (8%)
Query: 4 QLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQSGIG 63
+L S + +Q SLP LPVP + ++++YLESV+P + EEY + E + ++FQ
Sbjct: 157 RLLSSRHPMLYSFQTSLPKLPVPRVSATIQRYLESVRPLLDDEEYYRMELLAKEFQDKTA 216
Query: 64 EKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGTQLE 123
+L + L+ ++ N++ +WW YL R P +N N+ + Q
Sbjct: 217 PRLQKYLVLKSWWASNYVSDWWEEYIYLRGRSPLMVNSNYYV----MDLVLIKNTDVQAA 272
Query: 124 RGSITLWHNLNYWQLLRKEKV-PVHKVGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFRT 182
R + + Y + L +E++ PV +G P+ Q +F+T ++PG D + +
Sbjct: 273 RLGNIIHAMIMYRRKLDREEIKPVMALGIVPMCSYQMERMFNTTRIPGKDTDVLQHL--- 329
Query: 183 ESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTPPELLRQLTYIHKKCHSEPDGPG---IAA 239
S+ R H+ V +GR F + L+ P +L Q I P PG +AA
Sbjct: 330 -SDSR---HVAVYHKGRFFKLWLYEGARLLKPQDLEMQFQRILDD--PSPPQPGEEKLAA 383
Query: 240 LTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIA---A 296
LT+ R WA+AR+ +N A LE I+ + ++++ S PED + + A
Sbjct: 384 LTAGGRVEWAQARQAFFS-SGKNKAALEAIERAAFFVALDEESYSYDPEDEASLSLYGKA 442
Query: 297 ILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYV-----DEKIFQNEG 351
+L G+ RW DKS+ LISF NG G N +HA DA I+ ++ +V + G
Sbjct: 443 LLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTDSFHLGYTETG 502
Query: 352 RWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTKN 411
G P P L + + ++ I + A D+++ + F FGK L K
Sbjct: 503 HCLGKPNPALAP-PTRLQWDIPKQCQAVIESSYQVAKALADDVELYCFQFLPFGKGLIKK 561
Query: 412 KMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQD 471
PD F+Q+ALQLA++R G YE +MTR F GRTET+RSCT E+ + Q+M +
Sbjct: 562 CRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTRMFREGRTETVRSCTSESTAFVQAMME 621
Query: 472 PSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVP---ELFTDP 528
S + + +A KH M + G G DRHL L L++K G+ P E+ ++P
Sbjct: 622 GSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDRHLFCLYLVSKYLGVSSPFLAEVLSEP 681
Query: 529 LFSKSGGGGNFVLSTSLV--------------GYLRVQGVVVPMVHNGYGFFYHIRDDRF 574
+ LSTS + +L G P+ +GYG Y I +
Sbjct: 682 ----------WRLSTSQIPQSQIRMFDPEQHPNHLGAGGGFGPVADDGYGVSYMIAGENT 731
Query: 575 V-VACSAWKSCPETDAEK 591
+ S+ S ET+A++
Sbjct: 732 IFFHISSKFSSSETNAQR 749
>gi|209862905 carnitine palmitoyltransferase 1C isoform 1 [Homo
sapiens]
Length = 792
Score = 214 bits (545), Expect = 2e-55
Identities = 184/624 (29%), Positives = 293/624 (46%), Gaps = 63/624 (10%)
Query: 14 FQYQDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLER 73
F YQ SLP PVPS++++++KYLESV+P + E++ T + Q+F L L +
Sbjct: 165 FSYQRSLPRQPVPSVQDTVRKYLESVRPILSDEDFDWTAVLAQEFLRLQASLLQWYLRLK 224
Query: 74 AKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLW-HN 132
+ N++ +WW YL R P +N N+ AA + G + ++ L+ H
Sbjct: 225 SWWASNYVSDWWEEFVYLRSRNPLMVNSNYYMMAA--------RAGNAVH--ALLLYRHR 274
Query: 133 LNYWQLLRKEKVPVHKVGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNHI 192
LN R+E P +G PL Q+ +F+T ++PG+ +D I + ++ H+
Sbjct: 275 LN-----RQEIPPTLLMGMRPLCSAQYEKIFNTTRIPGVQKDYIRHLHDSQ-------HV 322
Query: 193 VVLCRGRAFVFDVIHEGCLVTPPELLRQLTYI-HKKCHSEPDGPGIAALTSEERTRWAKA 251
V RGR F L++P L +Q I + P +AALT+ R WA+
Sbjct: 323 AVFHRGRFFRMGTHSRNSLLSPRALEQQFQRILDDPSPACPHEEHLAALTAAPRGTWAQV 382
Query: 252 REYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIAA----ILIGDPTVRWG 307
R L + LE ++ + S++ +T ED + + A +L G RW
Sbjct: 383 RT---SLKTQAAEALEAVEGAAFFVSLDAEPAGLTREDPAASLDAYAHALLAGRGHDRWF 439
Query: 308 DKSYNLISFSNGVFGCNCDHAPFDAMIMVNI-SYYVDEKIFQ----NEGRWKGSEKVRDI 362
DKS+ LI FSNG G + +H+ D I ++ + + + FQ +G KG +
Sbjct: 440 DKSFTLIVFSNGKLGLSVEHSWADCPISGHMWEFTLATECFQLGYSTDGHCKGHPDPT-L 498
Query: 363 PLPEELIFIVDEKVLNDINQAK--AQYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFI 420
P P+ L + + +++ + I+ A A+ L E D + F+ FGK + L D+FI
Sbjct: 499 PQPQRLQWDLPDQIHSSISLALRGAKILSENVDCHVVP--FSLFGKSFIRRCHLSSDSFI 556
Query: 421 QLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQDPSVNLRERQ 480
Q+ALQLA++R G YE+AMTR F GRTET+RSCT EA + ++M+D +
Sbjct: 557 QIALQLAHFRDRGQFCLTYESAMTRLFLEGRTETVRSCTREACNFVRAMEDKEKTDPQCL 616
Query: 481 QKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVPELFTDPLFSKSGGGGNFV 540
A KH ++K +G+G DRHL L ++++ L P F + S+ +
Sbjct: 617 ALFRVAVDKHQALLKAAMSGQGVDRHLFALYIVSRFLHLQSP--FLTQVHSE-----QWQ 669
Query: 541 LSTSLV--------------GYLRVQGVVVPMVHNGYGFFYHIRDDRFVV-ACSAWKSCP 585
LSTS + Y+ G P +GYG Y D + S+ KS
Sbjct: 670 LSTSQIPVQQMHLFDVHNYPDYVSSGGGFGPADDHGYGVSYIFMGDGMITFHISSKKSST 729
Query: 586 ETDAEKLVQLTFCAFHDMIQLMNS 609
+TD+ +L Q A D+ L +
Sbjct: 730 KTDSHRLGQHIEDALLDVASLFQA 753
>gi|22748777 carnitine palmitoyltransferase 1C isoform 2 [Homo
sapiens]
Length = 803
Score = 213 bits (542), Expect = 4e-55
Identities = 180/624 (28%), Positives = 290/624 (46%), Gaps = 52/624 (8%)
Query: 14 FQYQDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLER 73
F YQ SLP PVPS++++++KYLESV+P + E++ T + Q+F L L +
Sbjct: 165 FSYQRSLPRQPVPSVQDTVRKYLESVRPILSDEDFDWTAVLAQEFLRLQASLLQWYLRLK 224
Query: 74 AKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNL 133
+ N++ +WW YL R P +N N+ + + Q R + L
Sbjct: 225 SWWASNYVSDWWEEFVYLRSRNPLMVNSNYY----MMDFLYVTPTPLQAARAGNAVHALL 280
Query: 134 NYWQLLRKEKVP-VHKVGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNHI 192
Y L ++++P +G PL Q+ +F+T ++PG+ +D I + ++ H+
Sbjct: 281 LYRHRLNRQEIPPTLLMGMRPLCSAQYEKIFNTTRIPGVQKDYIRHLHDSQ-------HV 333
Query: 193 VVLCRGRAFVFDVIHEGCLVTPPELLRQLTYI-HKKCHSEPDGPGIAALTSEERTRWAKA 251
V RGR F L++P L +Q I + P +AALT+ R WA+
Sbjct: 334 AVFHRGRFFRMGTHSRNSLLSPRALEQQFQRILDDPSPACPHEEHLAALTAAPRGTWAQV 393
Query: 252 REYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIAA----ILIGDPTVRWG 307
R L + LE ++ + S++ +T ED + + A +L G RW
Sbjct: 394 RT---SLKTQAAEALEAVEGAAFFVSLDAEPAGLTREDPAASLDAYAHALLAGRGHDRWF 450
Query: 308 DKSYNLISFSNGVFGCNCDHAPFDAMIMVNI-SYYVDEKIFQ----NEGRWKGSEKVRDI 362
DKS+ LI FSNG G + +H+ D I ++ + + + FQ +G KG +
Sbjct: 451 DKSFTLIVFSNGKLGLSVEHSWADCPISGHMWEFTLATECFQLGYSTDGHCKGHPDPT-L 509
Query: 363 PLPEELIFIVDEKVLNDINQAK--AQYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFI 420
P P+ L + + +++ + I+ A A+ L E D + F+ FGK + L D+FI
Sbjct: 510 PQPQRLQWDLPDQIHSSISLALRGAKILSENVDCHVVP--FSLFGKSFIRRCHLSSDSFI 567
Query: 421 QLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQDPSVNLRERQ 480
Q+ALQLA++R G YE+AMTR F GRTET+RSCT EA + ++M+D +
Sbjct: 568 QIALQLAHFRDRGQFCLTYESAMTRLFLEGRTETVRSCTREACNFVRAMEDKEKTDPQCL 627
Query: 481 QKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVPELFTDPLFSKSGGGGNFV 540
A KH ++K +G+G DRHL L ++++ L P F + S+ +
Sbjct: 628 ALFRVAVDKHQALLKAAMSGQGVDRHLFALYIVSRFLHLQSP--FLTQVHSE-----QWQ 680
Query: 541 LSTSLV--------------GYLRVQGVVVPMVHNGYGFFYHIRDDRFVV-ACSAWKSCP 585
LSTS + Y+ G P +GYG Y D + S+ KS
Sbjct: 681 LSTSQIPVQQMHLFDVHNYPDYVSSGGGFGPADDHGYGVSYIFMGDGMITFHISSKKSST 740
Query: 586 ETDAEKLVQLTFCAFHDMIQLMNS 609
+TD+ +L Q A D+ L +
Sbjct: 741 KTDSHRLGQHIEDALLDVASLFQA 764
>gi|223468670 carnitine palmitoyltransferase 1B isoform c [Homo
sapiens]
Length = 738
Score = 204 bits (520), Expect = 1e-52
Identities = 171/587 (29%), Positives = 270/587 (45%), Gaps = 55/587 (9%)
Query: 35 YLESVKPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVR 94
YLESV+P + EEY + E + ++FQ +L + L+ ++ N++ +WW YL R
Sbjct: 154 YLESVRPLLDDEEYYRMELLAKEFQDKTAPRLQKYLVLKSWWASNYVSDWWEEYIYLRGR 213
Query: 95 IPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKV-PVHKVGNTP 153
P +N N+ + Q R + + Y + L +E++ PV +G P
Sbjct: 214 SPLMVNSNYYV----MDLVLIKNTDVQAARLGNIIHAMIMYRRKLDREEIKPVMALGIVP 269
Query: 154 LDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLVT 213
+ Q +F+T ++PG D + + S+ R H+ V +GR F + L+
Sbjct: 270 MCSYQMERMFNTTRIPGKDTDVLQHL----SDSR---HVAVYHKGRFFKLWLYEGARLLK 322
Query: 214 PPELLRQLTYIHKKCHSEPDGPG---IAALTSEERTRWAKAREYLIGLDPENLALLEKIQ 270
P +L Q I P PG +AALT+ R WA+AR+ +N A LE I+
Sbjct: 323 PQDLEMQFQRILDD--PSPPQPGEEKLAALTAGGRVEWAQARQAFFS-SGKNKAALEAIE 379
Query: 271 SSLLVYSMEDSSPHVTPEDYSEIIA---AILIGDPTVRWGDKSYNLISFSNGVFGCNCDH 327
+ ++++ S PED + + A+L G+ RW DKS+ LISF NG G N +H
Sbjct: 380 RAAFFVALDEESYSYDPEDEASLSLYGKALLHGNCYNRWFDKSFTLISFKNGQLGLNAEH 439
Query: 328 APFDAMIMVNISYYV-----DEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQ 382
A DA I+ ++ +V + G G P P L + + ++ I
Sbjct: 440 AWADAPIIGHLWEFVLGTDSFHLGYTETGHCLGKPNPALAP-PTRLQWDIPKQCQAVIES 498
Query: 383 AKAQYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETA 442
+ A D+++ + F FGK L K PD F+Q+ALQLA++R G YE +
Sbjct: 499 SYQVAKALADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDRGKFCLTYEAS 558
Query: 443 MTRHFYHGRTETMRSCTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKG 502
MTR F GRTET+RSCT E+ + Q+M + S + + +A KH M + G G
Sbjct: 559 MTRMFREGRTETVRSCTSESTAFVQAMMEGSHTKADLRDLFQKAAKKHQNMYRLAMTGAG 618
Query: 503 FDRHLLGLLLIAKEEGLPVP---ELFTDPLFSKSGGGGNFVLSTSLV------------- 546
DRHL L L++K G+ P E+ ++P + LSTS +
Sbjct: 619 IDRHLFCLYLVSKYLGVSSPFLAEVLSEP----------WRLSTSQIPQSQIRMFDPEQH 668
Query: 547 -GYLRVQGVVVPMVHNGYGFFYHIRDDRFV-VACSAWKSCPETDAEK 591
+L G P+ +GYG Y I + + S+ S ET+A++
Sbjct: 669 PNHLGAGGGFGPVADDGYGVSYMIAGENTIFFHISSKFSSSETNAQR 715
>gi|223468674 carnitine palmitoyltransferase 1B isoform d [Homo
sapiens]
Length = 691
Score = 127 bits (319), Expect = 3e-29
Identities = 100/319 (31%), Positives = 149/319 (46%), Gaps = 34/319 (10%)
Query: 296 AILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYV-----DEKIFQNE 350
A+L G+ RW DKS+ LISF NG G N +HA DA I+ ++ +V +
Sbjct: 361 ALLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTDSFHLGYTET 420
Query: 351 GRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTK 410
G G P P L + + ++ I + A D+++ + F FGK L K
Sbjct: 421 GHCLGKPNPALAP-PTRLQWDIPKQCQAVIESSYQVAKALADDVELYCFQFLPFGKGLIK 479
Query: 411 NKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQ 470
PD F+Q+ALQLA++R G YE +MTR F GRTET+RSCT E+ + Q+M
Sbjct: 480 KCRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTRMFREGRTETVRSCTSESTAFVQAMM 539
Query: 471 DPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVP---ELFTD 527
+ S + + +A KH M + G G DRHL L L++K G+ P E+ ++
Sbjct: 540 EGSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDRHLFCLYLVSKYLGVSSPFLAEVLSE 599
Query: 528 PLFSKSGGGGNFVLSTSLV--------------GYLRVQGVVVPMVHNGYGFFYHIRDDR 573
P + LSTS + +L G P+ +GYG Y I +
Sbjct: 600 P----------WRLSTSQIPQSQIRMFDPEQHPNHLGAGGGFGPVADDGYGVSYMIAGEN 649
Query: 574 FV-VACSAWKSCPETDAEK 591
+ S+ S ET+A++
Sbjct: 650 TIFFHISSKFSSSETNAQR 668
Score = 84.7 bits (208), Expect = 2e-16
Identities = 55/199 (27%), Positives = 97/199 (48%), Gaps = 12/199 (6%)
Query: 4 QLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQSGIG 63
+L S + +Q SLP LPVP + ++++YLESV+P + EEY + E + ++FQ
Sbjct: 157 RLLSSRHPMLYSFQTSLPKLPVPRVSATIQRYLESVRPLLDDEEYYRMELLAKEFQDKTA 216
Query: 64 EKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGTQLE 123
+L + L+ ++ N++ +WW YL R P +N N+ + Q
Sbjct: 217 PRLQKYLVLKSWWASNYVSDWWEEYIYLRGRSPLMVNSNY----YVMDLVLIKNTDVQAA 272
Query: 124 RGSITLWHNLNYWQLLRKEKV-PVHKVGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFRT 182
R + + Y + L +E++ PV +G P+ Q +F+T ++PG D + +
Sbjct: 273 RLGNIIHAMIMYRRKLDREEIKPVMALGIVPMCSYQMERMFNTTRIPGKDTDVLQHL--- 329
Query: 183 ESEGRSPNHIVVLCRGRAF 201
S+ R H+ V +GR F
Sbjct: 330 -SDSR---HVAVYHKGRFF 344
>gi|58535453 CDK5 regulatory subunit associated protein 2 isoform b
[Homo sapiens]
Length = 1814
Score = 36.2 bits (82), Expect = 0.091
Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 2 ENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTE-EIVQKFQS 60
+N+L + EE YQ LP P PS +L Y S K F ++++ + E E +
Sbjct: 1329 QNELMERIEEDNLTYQHLLPESPEPSASHALSDYETSEKSFFSRDQKQDNETEKTSVMVN 1388
Query: 61 GIGEKLHQKLLERAKGKRNWLEE 83
+ L + ++ + R LEE
Sbjct: 1389 SFSQDLLMEHIQEIRTLRKRLEE 1411
>gi|58535451 CDK5 regulatory subunit associated protein 2 isoform a
[Homo sapiens]
Length = 1893
Score = 36.2 bits (82), Expect = 0.091
Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 2 ENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTE-EIVQKFQS 60
+N+L + EE YQ LP P PS +L Y S K F ++++ + E E +
Sbjct: 1329 QNELMERIEEDNLTYQHLLPESPEPSASHALSDYETSEKSFFSRDQKQDNETEKTSVMVN 1388
Query: 61 GIGEKLHQKLLERAKGKRNWLEE 83
+ L + ++ + R LEE
Sbjct: 1389 SFSQDLLMEHIQEIRTLRKRLEE 1411
>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
b [Homo sapiens]
Length = 882
Score = 33.9 bits (76), Expect = 0.45
Identities = 51/200 (25%), Positives = 80/200 (40%), Gaps = 20/200 (10%)
Query: 7 KSTEERTFQYQDSLPSLP--VPSLEESLKKY---LESVKPFANQEEY------KKTEEIV 55
KS ++ Q Q+ L + + EE +KK L ++ F + E KK EE+
Sbjct: 615 KSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFHQESELEVHAFDKKLEEM- 673
Query: 56 QKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWP 115
Q +K HQ L+ K L E+ +A L + P +
Sbjct: 674 -SCQVLQWQKQHQNDLKMLAAKEEQLREFQEEMAALKENLLEDDKEPCCLP-----QWSV 727
Query: 116 PKEGTQLERGSITLWHNLNYWQLLRKEKVPVHKVGNTPLDMNQFRMLFSTCKVPGITRDS 175
PK+ +L RG+ + NL W +++KV K+GN + ++ S K TR S
Sbjct: 728 PKDTCRLYRGNDQIMTNLEQW--AKQQKVANEKLGNQLREQVKYIAKLSGEKDREPTRAS 785
Query: 176 IMNYFRTESEGRSPNHIVVL 195
N R S S H V++
Sbjct: 786 SPNTTRPSSPSHSHLHSVMV 805
>gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens]
Length = 2539
Score = 33.5 bits (75), Expect = 0.59
Identities = 30/88 (34%), Positives = 40/88 (45%), Gaps = 6/88 (6%)
Query: 207 HEGCLVTPPELLRQLTYIHKKCHSEPDGPGIAALTSEERTRWAKAREYLIGL-DPENLAL 265
H C L L + + PG A L S T A+ ++YL + D L L
Sbjct: 518 HSQCQDCKDSLSEDLASATEPANDSLSSPGAANLFS---TYLARCQQYLCSIPDSLCLEL 574
Query: 266 LEKIQSSLLVYSME-DSSPHVTPEDYSE 292
LE I S LL+ S + PH+ PEDY+E
Sbjct: 575 LENIFSLLLITSADLHPEPHL-PEDYAE 601
>gi|91208426 U5 snRNP-specific protein [Homo sapiens]
Length = 2335
Score = 32.0 bits (71), Expect = 1.7
Identities = 28/136 (20%), Positives = 59/136 (43%), Gaps = 24/136 (17%)
Query: 250 KAREYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIAAILIGDPTVRWGDK 309
+A ++ +P L E+I+ L +YS E + P+++ ++Y E+ + +I W
Sbjct: 1728 QAMAKIMKANPALYVLRERIRKGLQLYSSEPTEPYLSSQNYGELFSNQII------WFVD 1781
Query: 310 SYNLISFS-NGVFGCNCDHAPFDAMI-------------MVNISYYVDEKIFQNEGRWKG 355
N+ + + F N P + I +++ S + +K +WK
Sbjct: 1782 DTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKT 1841
Query: 356 SEKV----RDIPLPEE 367
+E+V R +P+ E+
Sbjct: 1842 AEEVAALIRSLPVEEQ 1857
>gi|132814467 glutamyl aminopeptidase [Homo sapiens]
Length = 957
Score = 31.6 bits (70), Expect = 2.2
Identities = 18/66 (27%), Positives = 33/66 (50%), Gaps = 8/66 (12%)
Query: 31 SLKKYLESVKPFANQEEYKKTEEIVQKF-QSGIGEKLHQKLLERAKGKRNWLE------- 82
+L + + +PF + + + E K+ Q+G GEK +++LE K WL+
Sbjct: 888 NLGRIVTIAEPFNTELQLWQMESFFAKYPQAGAGEKPREQVLETVKNNIEWLKQHRNTIR 947
Query: 83 EWWLNV 88
EW+ N+
Sbjct: 948 EWFFNL 953
>gi|117968420 NUF2, NDC80 kinetochore complex component [Homo
sapiens]
Length = 464
Score = 30.8 bits (68), Expect = 3.8
Identities = 17/50 (34%), Positives = 29/50 (58%), Gaps = 3/50 (6%)
Query: 29 EESLKKY--LESVKPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLERAKG 76
+E+L K L+SV P QEE+K+ + +Q+ Q + + HQK + +G
Sbjct: 160 QEALMKLERLDSV-PVEEQEEFKQLSDGIQELQQSLNQDFHQKTIVLQEG 208
>gi|117968353 NUF2, NDC80 kinetochore complex component [Homo
sapiens]
Length = 464
Score = 30.8 bits (68), Expect = 3.8
Identities = 17/50 (34%), Positives = 29/50 (58%), Gaps = 3/50 (6%)
Query: 29 EESLKKY--LESVKPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLERAKG 76
+E+L K L+SV P QEE+K+ + +Q+ Q + + HQK + +G
Sbjct: 160 QEALMKLERLDSV-PVEEQEEFKQLSDGIQELQQSLNQDFHQKTIVLQEG 208
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,896,328
Number of Sequences: 37866
Number of extensions: 1156534
Number of successful extensions: 2584
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2438
Number of HSP's gapped (non-prelim): 40
length of query: 612
length of database: 18,247,518
effective HSP length: 108
effective length of query: 504
effective length of database: 14,157,990
effective search space: 7135626960
effective search space used: 7135626960
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.