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Search of human proteins with 31377720
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31377720 pleckstrin homology domain containing, family A
(phosphoinositide binding specific) member 1 [Homo sapiens]
(404 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50234893 pleckstrin homology domain containing, family A (pho... 818 0.0
gi|31377720 pleckstrin homology domain containing, family A (pho... 818 0.0
gi|154146216 pleckstrin homology domain containing, family A (ph... 328 5e-90
gi|158631203 dual adaptor of phosphotyrosine and 3-phosphoinosit... 70 4e-12
gi|110349763 cytohesin 1 isoform 2 [Homo sapiens] 61 2e-09
gi|37595548 phosphoinositol 3-phosphate-binding protein-3 [Homo ... 60 3e-09
gi|38201692 RAS p21 protein activator 3 [Homo sapiens] 59 8e-09
gi|4758964 cytohesin 1 isoform 1 [Homo sapiens] 58 2e-08
gi|55741447 pleckstrin homology domain containing, family H (wit... 57 2e-08
gi|217416392 pleckstrin homology domain containing, family H (wi... 56 5e-08
gi|46370073 GRB2-associated binding protein 1 isoform b [Homo sa... 56 7e-08
gi|46370071 GRB2-associated binding protein 1 isoform a [Homo sa... 56 7e-08
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 55 1e-07
gi|7706643 pleckstrin 2 [Homo sapiens] 55 1e-07
gi|4758968 cytohesin 3 [Homo sapiens] 54 2e-07
gi|4502023 AKT2 kinase [Homo sapiens] 54 3e-07
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] 54 3e-07
gi|156616273 pleckstrin [Homo sapiens] 54 3e-07
gi|7661880 centaurin beta1 [Homo sapiens] 54 3e-07
gi|195972859 cytohesin 2 isoform 2 [Homo sapiens] 54 3e-07
gi|187608516 centaurin, beta 2 [Homo sapiens] 53 6e-07
gi|18105042 GRB2-associated binding protein 2 isoform a [Homo sa... 52 1e-06
gi|93102364 SWAP-70 protein [Homo sapiens] 52 1e-06
gi|21264592 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom... 52 1e-06
gi|154354979 myosin X [Homo sapiens] 50 3e-06
gi|206597515 ArfGAP with RhoGAP domain, ankyrin repeat and PH do... 50 4e-06
gi|206597513 ArfGAP with RhoGAP domain, ankyrin repeat and PH do... 50 4e-06
gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom... 50 4e-06
gi|8670546 cytohesin 2 isoform 1 [Homo sapiens] 50 4e-06
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa... 50 5e-06
>gi|50234893 pleckstrin homology domain containing, family A
(phosphoinositide binding specific) member 1 [Homo
sapiens]
Length = 404
Score = 818 bits (2114), Expect = 0.0
Identities = 404/404 (100%), Positives = 404/404 (100%)
Query: 1 MPYVDRQNRICGFLDIEENENSGKFLRRYFILDTREDSFVWYMDNPQNLPSGSSRVGAIK 60
MPYVDRQNRICGFLDIEENENSGKFLRRYFILDTREDSFVWYMDNPQNLPSGSSRVGAIK
Sbjct: 1 MPYVDRQNRICGFLDIEENENSGKFLRRYFILDTREDSFVWYMDNPQNLPSGSSRVGAIK 60
Query: 61 LTYISKVSDATKLRPKAEFCFVMNAGMRKYFLQANDQQDLVEWVNVLNKAIKITVPKQSD 120
LTYISKVSDATKLRPKAEFCFVMNAGMRKYFLQANDQQDLVEWVNVLNKAIKITVPKQSD
Sbjct: 61 LTYISKVSDATKLRPKAEFCFVMNAGMRKYFLQANDQQDLVEWVNVLNKAIKITVPKQSD 120
Query: 121 SQPNSDNLSRHGECGKKQVSYRTDIVGGVPIITPTQKEEVNECGESIDRNNLKRSQSHLP 180
SQPNSDNLSRHGECGKKQVSYRTDIVGGVPIITPTQKEEVNECGESIDRNNLKRSQSHLP
Sbjct: 121 SQPNSDNLSRHGECGKKQVSYRTDIVGGVPIITPTQKEEVNECGESIDRNNLKRSQSHLP 180
Query: 181 YFTPKPPQDSAVIKAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPLKEV 240
YFTPKPPQDSAVIKAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPLKEV
Sbjct: 181 YFTPKPPQDSAVIKAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPLKEV 240
Query: 241 HKVQECKQSDIMMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVSGAIVAQRGPGRSASS 300
HKVQECKQSDIMMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVSGAIVAQRGPGRSASS
Sbjct: 241 HKVQECKQSDIMMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVSGAIVAQRGPGRSASS 300
Query: 301 EHPPGPSESKHAFRPTNAATATSHSTASRSNSLVSTFTMEKRGFYESLAKVKPGNFKVQT 360
EHPPGPSESKHAFRPTNAATATSHSTASRSNSLVSTFTMEKRGFYESLAKVKPGNFKVQT
Sbjct: 301 EHPPGPSESKHAFRPTNAATATSHSTASRSNSLVSTFTMEKRGFYESLAKVKPGNFKVQT 360
Query: 361 VSPREPASKVTEQALLRPQSKNGPQEKDCDLVDLDDASLPVSDV 404
VSPREPASKVTEQALLRPQSKNGPQEKDCDLVDLDDASLPVSDV
Sbjct: 361 VSPREPASKVTEQALLRPQSKNGPQEKDCDLVDLDDASLPVSDV 404
>gi|31377720 pleckstrin homology domain containing, family A
(phosphoinositide binding specific) member 1 [Homo
sapiens]
Length = 404
Score = 818 bits (2114), Expect = 0.0
Identities = 404/404 (100%), Positives = 404/404 (100%)
Query: 1 MPYVDRQNRICGFLDIEENENSGKFLRRYFILDTREDSFVWYMDNPQNLPSGSSRVGAIK 60
MPYVDRQNRICGFLDIEENENSGKFLRRYFILDTREDSFVWYMDNPQNLPSGSSRVGAIK
Sbjct: 1 MPYVDRQNRICGFLDIEENENSGKFLRRYFILDTREDSFVWYMDNPQNLPSGSSRVGAIK 60
Query: 61 LTYISKVSDATKLRPKAEFCFVMNAGMRKYFLQANDQQDLVEWVNVLNKAIKITVPKQSD 120
LTYISKVSDATKLRPKAEFCFVMNAGMRKYFLQANDQQDLVEWVNVLNKAIKITVPKQSD
Sbjct: 61 LTYISKVSDATKLRPKAEFCFVMNAGMRKYFLQANDQQDLVEWVNVLNKAIKITVPKQSD 120
Query: 121 SQPNSDNLSRHGECGKKQVSYRTDIVGGVPIITPTQKEEVNECGESIDRNNLKRSQSHLP 180
SQPNSDNLSRHGECGKKQVSYRTDIVGGVPIITPTQKEEVNECGESIDRNNLKRSQSHLP
Sbjct: 121 SQPNSDNLSRHGECGKKQVSYRTDIVGGVPIITPTQKEEVNECGESIDRNNLKRSQSHLP 180
Query: 181 YFTPKPPQDSAVIKAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPLKEV 240
YFTPKPPQDSAVIKAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPLKEV
Sbjct: 181 YFTPKPPQDSAVIKAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPLKEV 240
Query: 241 HKVQECKQSDIMMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVSGAIVAQRGPGRSASS 300
HKVQECKQSDIMMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVSGAIVAQRGPGRSASS
Sbjct: 241 HKVQECKQSDIMMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVSGAIVAQRGPGRSASS 300
Query: 301 EHPPGPSESKHAFRPTNAATATSHSTASRSNSLVSTFTMEKRGFYESLAKVKPGNFKVQT 360
EHPPGPSESKHAFRPTNAATATSHSTASRSNSLVSTFTMEKRGFYESLAKVKPGNFKVQT
Sbjct: 301 EHPPGPSESKHAFRPTNAATATSHSTASRSNSLVSTFTMEKRGFYESLAKVKPGNFKVQT 360
Query: 361 VSPREPASKVTEQALLRPQSKNGPQEKDCDLVDLDDASLPVSDV 404
VSPREPASKVTEQALLRPQSKNGPQEKDCDLVDLDDASLPVSDV
Sbjct: 361 VSPREPASKVTEQALLRPQSKNGPQEKDCDLVDLDDASLPVSDV 404
>gi|154146216 pleckstrin homology domain containing, family A
(phosphoinositide binding specific) member 2 [Homo
sapiens]
Length = 425
Score = 328 bits (841), Expect = 5e-90
Identities = 174/308 (56%), Positives = 220/308 (71%), Gaps = 9/308 (2%)
Query: 1 MPYVDRQNRICGFLDIEENENSGKFLRRYFILDTREDSFVWYMDNPQNLPSGSSRVGAIK 60
MPYVDRQNRICGFLDIEE+ENSGKFLRRYFILDT+ + +WYMDNPQNL G+ VGA++
Sbjct: 1 MPYVDRQNRICGFLDIEEHENSGKFLRRYFILDTQANCLLWYMDNPQNLAMGAGAVGALQ 60
Query: 61 LTYISKVSDAT-KLRPKAEFCFVMNAGMRKYFLQANDQQDLVEWVNVLNKAIKITVPKQS 119
LTYISKVS AT K +PK FCFV+NA ++YFLQANDQ+D+ +WV LN+A KITVPK
Sbjct: 61 LTYISKVSIATPKQKPKTPFCFVINALSQRYFLQANDQKDMKDWVEALNQASKITVPKGG 120
Query: 120 DSQPNSD---NLSRHGECGKK-QVSYRTDIVGGVPIITPTQKE--EVNECGESIDRNNLK 173
++ +L+ KK QV+Y+T+I+GGV + TP + + E E L+
Sbjct: 121 GLPMTTEVLKSLAAPPALEKKPQVAYKTEIIGGVVVHTPISQNGGDGQEGSEPGSHTILR 180
Query: 174 RSQSHLPYFTPKPPQDSAVIKAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLR 233
RSQS++P + +IK+GYCVKQG V K+WKRR+F LD+ TI YFK E ++EPLR
Sbjct: 181 RSQSYIPTSGCRASTGPPLIKSGYCVKQGNVRKSWKRRFFALDDFTICYFKCEQDREPLR 240
Query: 234 VIPLKEVHKVQEC--KQSDIMMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVSGAIVAQ 291
I LK+V K EC K D++MRDNLFEI+T+SRTFYVQADSPE+MHSWIK + A+ A
Sbjct: 241 TIFLKDVLKTHECLVKSGDLLMRDNLFEIITSSRTFYVQADSPEDMHSWIKEIGAAVQAL 300
Query: 292 RGPGRSAS 299
+ R S
Sbjct: 301 KCHPRETS 308
>gi|158631203 dual adaptor of phosphotyrosine and
3-phosphoinositides [Homo sapiens]
Length = 280
Score = 69.7 bits (169), Expect = 4e-12
Identities = 38/97 (39%), Positives = 51/97 (52%), Gaps = 3/97 (3%)
Query: 186 PPQDSAVIKAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPLKEVHKVQE 245
P S K GY KQG ++K WK R+F L N + YFK ++ EP+R++ L E VQ
Sbjct: 159 PTAPSLGTKEGYLTKQGGLVKTWKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQF 218
Query: 246 CKQSDIMMRDNLFEIVTTSRTFYVQADSPEEMHSWIK 282
+ R N F +V RTFY+ A + E WIK
Sbjct: 219 DYSQE---RVNCFCLVFPFRTFYLCAKTGVEADEWIK 252
>gi|110349763 cytohesin 1 isoform 2 [Homo sapiens]
Length = 397
Score = 61.2 bits (147), Expect = 2e-09
Identities = 33/113 (29%), Positives = 60/113 (53%), Gaps = 18/113 (15%)
Query: 194 KAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPLK--EVHKVQECKQS-- 249
+ G+ +K G +K WKRR+F L +N + YF+ +KEP +IPL+ + +V++ K+
Sbjct: 263 REGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNC 322
Query: 250 -DIMMRDNLFEIVTTSRT-------------FYVQADSPEEMHSWIKAVSGAI 288
++ + DN +++ +T + + A +PEE WIK + AI
Sbjct: 323 FELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAI 375
>gi|37595548 phosphoinositol 3-phosphate-binding protein-3 [Homo
sapiens]
Length = 1048
Score = 60.5 bits (145), Expect = 3e-09
Identities = 48/151 (31%), Positives = 73/151 (48%), Gaps = 16/151 (10%)
Query: 176 QSHLPYFTPKPPQDSAVIKAGYCVKQGAV-MKNWKRRYFQLDENTIGYFKSELEKEPLRV 234
+SH P P V KAG+ KQ + +K W +R+F L + + Y+K E E+ L
Sbjct: 48 RSHSMKRNPNAP----VTKAGWLFKQASSGVKQWNKRWFVLVDRCLFYYKDEKEESILGS 103
Query: 235 IPLKEVHKVQECKQSDIMMRDNLFEIVTTS-RTFYVQADSPEEMHSWIKAVSGAIVAQRG 293
IPL +V + SD + R + F+ RT++ A+SPEE +WI+A+ A Q
Sbjct: 104 IPLLSF-RVAAVQPSDNISRKHTFKAEHAGVRTYFFSAESPEEQEAWIQAMGEAARVQIP 162
Query: 294 PGRSA-------SSEHPPGPS--ESKHAFRP 315
P + + S E P + SKH +P
Sbjct: 163 PAQKSVPQAVRHSHEKPDSENVPPSKHHQQP 193
Score = 35.8 bits (81), Expect = 0.071
Identities = 24/115 (20%), Positives = 53/115 (46%), Gaps = 8/115 (6%)
Query: 12 GFLDIEENENSGKFLRRYFILDTREDSFVWYMDNPQNLPSGSSRVGAIKLTYISKVSDAT 71
G+L + + ++ +R+F+L R +Y D + GS + + ++ + + +
Sbjct: 64 GWLFKQASSGVKQWNKRWFVLVDR--CLFYYKDEKEESILGSIPLLSFRVAAVQPSDNIS 121
Query: 72 KLRP-KAEFCFVMNAGMRKYFLQANDQQDLVEWVNVLNKAIKITVPKQSDSQPNS 125
+ KAE +AG+R YF A ++ W+ + +A ++ +P S P +
Sbjct: 122 RKHTFKAE-----HAGVRTYFFSAESPEEQEAWIQAMGEAARVQIPPAQKSVPQA 171
>gi|38201692 RAS p21 protein activator 3 [Homo sapiens]
Length = 834
Score = 58.9 bits (141), Expect = 8e-09
Identities = 31/103 (30%), Positives = 59/103 (57%), Gaps = 7/103 (6%)
Query: 184 PKPPQDSAVIKAGYCVKQGAV-----MKNWKRRYFQLDENTIGYFKSELEKEPLRVIPLK 238
PK + V+K G+ +K+ MKN+K+R+F+L + Y KS+ + +PL IP++
Sbjct: 569 PKSVEQPIVLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYHKSKGD-QPLYSIPIE 627
Query: 239 EVHKVQECKQSDIMMRDNLFEIVTTSRTFYVQADSPEEMHSWI 281
+ V++ ++ M+ N+F+++ R Y+QA++ E WI
Sbjct: 628 NILAVEKLEEESFKMK-NMFQVIQPERALYIQANNCVEAKDWI 669
>gi|4758964 cytohesin 1 isoform 1 [Homo sapiens]
Length = 398
Score = 57.8 bits (138), Expect = 2e-08
Identities = 34/121 (28%), Positives = 62/121 (51%), Gaps = 23/121 (19%)
Query: 186 PPQDSAVIKAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPLK--EVHKV 243
P ++ ++K G G +K WKRR+F L +N + YF+ +KEP +IPL+ + +V
Sbjct: 261 PDREGWLLKLG-----GGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREV 315
Query: 244 QECKQS---DIMMRDNLFEIVTTSRT-------------FYVQADSPEEMHSWIKAVSGA 287
++ K+ ++ + DN +++ +T + + A +PEE WIK + A
Sbjct: 316 EDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAA 375
Query: 288 I 288
I
Sbjct: 376 I 376
>gi|55741447 pleckstrin homology domain containing, family H (with
MyTH4 domain) member 1 [Homo sapiens]
Length = 1364
Score = 57.4 bits (137), Expect = 2e-08
Identities = 29/100 (29%), Positives = 55/100 (55%), Gaps = 8/100 (8%)
Query: 194 KAGYCVKQGAVMKNWKRRYFQLDENTIGYFK--SELEKEPLRVIPLKEVHKVQECKQSDI 251
K+GY +K G+ +K WKRR+F L + I Y+K S++ ++P + L ++ + S
Sbjct: 581 KSGYLLKMGSQVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQIVRGEGS-- 638
Query: 252 MMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVSGAIVAQ 291
F++++ +T+Y+ ADSP + WI+ + + Q
Sbjct: 639 ----QTFQLISEKKTYYLTADSPSLLEEWIRVLQSLLKVQ 674
>gi|217416392 pleckstrin homology domain containing, family H (with
MyTH4 domain) member 2 [Homo sapiens]
Length = 1493
Score = 56.2 bits (134), Expect = 5e-08
Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 8/113 (7%)
Query: 194 KAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPLKEVHKVQECKQSDIMM 253
K+GY +K +K+WKRR+F L + Y+KS P VI + H ++ I+
Sbjct: 706 KSGYLLKMSGKVKSWKRRWFVLKGGELLYYKS-----PSDVIRKPQGH-IELSASCSILR 759
Query: 254 RDN--LFEIVTTSRTFYVQADSPEEMHSWIKAVSGAIVAQRGPGRSASSEHPP 304
DN ++ T T+Y+ ADSP + WIK + + Q S E P
Sbjct: 760 GDNKQTVQLTTEKHTYYLTADSPNILEEWIKVLQNVLRVQAANPLSLQPEGKP 812
>gi|46370073 GRB2-associated binding protein 1 isoform b [Homo
sapiens]
Length = 694
Score = 55.8 bits (133), Expect = 7e-08
Identities = 43/143 (30%), Positives = 66/143 (46%), Gaps = 30/143 (20%)
Query: 208 WKRRYFQL-------DENTIGYFKSELEKEPLRVIPLKEVHKVQECKQSDIMMRDN---- 256
WKRR+F L D + + Y+K++ K+P+R+I L C+Q D + N
Sbjct: 26 WKRRWFVLRSGRLTGDPDVLEYYKNDHAKKPIRIIDLNL------CQQVDAGLTFNKKEF 79
Query: 257 ----LFEIVTTSRTFYVQADSPEEMHSWIKA---VSGAIVAQRGPGRSASSEHPPGPSES 309
+F+I T R FY+ ADS EEM+ W++ + G + P + PPG S
Sbjct: 80 ENSYIFDINTIDRIFYLVADSEEEMNKWVRCICDICGFNPTEEDPVK------PPGSSLQ 133
Query: 310 KHAFRPTNAATATSHSTASRSNS 332
A P TA + A S++
Sbjct: 134 APADLPLAINTAPPSTQADSSSA 156
>gi|46370071 GRB2-associated binding protein 1 isoform a [Homo
sapiens]
Length = 724
Score = 55.8 bits (133), Expect = 7e-08
Identities = 43/143 (30%), Positives = 66/143 (46%), Gaps = 30/143 (20%)
Query: 208 WKRRYFQL-------DENTIGYFKSELEKEPLRVIPLKEVHKVQECKQSDIMMRDN---- 256
WKRR+F L D + + Y+K++ K+P+R+I L C+Q D + N
Sbjct: 26 WKRRWFVLRSGRLTGDPDVLEYYKNDHAKKPIRIIDLNL------CQQVDAGLTFNKKEF 79
Query: 257 ----LFEIVTTSRTFYVQADSPEEMHSWIKA---VSGAIVAQRGPGRSASSEHPPGPSES 309
+F+I T R FY+ ADS EEM+ W++ + G + P + PPG S
Sbjct: 80 ENSYIFDINTIDRIFYLVADSEEEMNKWVRCICDICGFNPTEEDPVK------PPGSSLQ 133
Query: 310 KHAFRPTNAATATSHSTASRSNS 332
A P TA + A S++
Sbjct: 134 APADLPLAINTAPPSTQADSSSA 156
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 54.7 bits (130), Expect = 1e-07
Identities = 35/103 (33%), Positives = 52/103 (50%), Gaps = 8/103 (7%)
Query: 192 VIKAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPLKEVHKVQECKQSDI 251
V+K GY K+G + +NW R+FQL + + YF SE KE +IPL + H C +
Sbjct: 217 VLKQGYLWKRGHLRRNWAERWFQLQPSCLCYFGSEECKEKRGIIPL-DAH----CCVEVL 271
Query: 252 MMRDN---LFEIVTTSRTFYVQADSPEEMHSWIKAVSGAIVAQ 291
RD +F + T +RT+ + A + W A+ AI Q
Sbjct: 272 PDRDGKRCMFCVKTANRTYEMSASDTRQRQEWTAAIQMAIRLQ 314
>gi|7706643 pleckstrin 2 [Homo sapiens]
Length = 353
Score = 54.7 bits (130), Expect = 1e-07
Identities = 38/113 (33%), Positives = 63/113 (55%), Gaps = 9/113 (7%)
Query: 189 DSAVIKAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPLKEVHKVQECKQ 248
+ V+K G+ VK+G ++ NWK R+F L +NT+ Y+K E + RV P K + C
Sbjct: 2 EDGVLKEGFLVKRGHIVHNWKARWFILRQNTLVYYKLEGGR---RVTPPKGRILLDGCTI 58
Query: 249 S----DIMMRDNLFEIVT-TSRTFYVQADSPEEMHSWIKAVSGAIVAQRGPGR 296
+ + R L ++ T TS ++++A S EE +W ++GAI A + PG+
Sbjct: 59 TCPCLEYENRPLLIKLKTQTSTEYFLEACSREERDAWAFEITGAIHAGQ-PGK 110
Score = 46.2 bits (108), Expect = 5e-05
Identities = 35/104 (33%), Positives = 53/104 (50%), Gaps = 13/104 (12%)
Query: 192 VIKAGYCVKQGAVMKNWKRRYFQL--DENTIGYF-KSELEKEPLRVIPLK-------EVH 241
V+K GY KQG KNWK R F L D + Y+ S+ E P+ L+ E +
Sbjct: 248 VVKQGYLAKQGHKRKNWKVRRFVLRKDPAFLHYYDPSKEENRPVGGFSLRGSLVSALEDN 307
Query: 242 KVQECKQSDIMMRDNLFEIVTTSRT-FYVQADSPEEMHSWIKAV 284
V + ++ + NLF+++T T +Y+QA S E WI+A+
Sbjct: 308 GVPTGVKGNV--QGNLFKVITKDDTHYYIQASSKAERAEWIEAI 349
>gi|4758968 cytohesin 3 [Homo sapiens]
Length = 399
Score = 54.3 bits (129), Expect = 2e-07
Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 26/117 (22%)
Query: 194 KAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPLKEVHKVQECKQSDIMM 253
+ G+ +K G +K WKRR+F L +N + YF+ +KEP +IPL+ + ++ +
Sbjct: 267 REGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENL----SIREVEDPR 322
Query: 254 RDNLFEIVTTSR----------------------TFYVQADSPEEMHSWIKAVSGAI 288
+ N FE+ S + + A SPEE W+K++ +I
Sbjct: 323 KPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASI 379
>gi|4502023 AKT2 kinase [Homo sapiens]
Length = 481
Score = 53.9 bits (128), Expect = 3e-07
Identities = 43/130 (33%), Positives = 60/130 (46%), Gaps = 15/130 (11%)
Query: 191 AVIKAGYCVKQGAVMKNWKRRYFQL--DENTIGYFKSELEKEPLRVIPLKEVHKVQECK- 247
+VIK G+ K+G +K W+ RYF L D + IGY E + P + +P V EC+
Sbjct: 5 SVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGY--KERPEAPDQTLPPLNNFSVAECQL 62
Query: 248 QSDIMMRDNLFEI------VTTSRTFYVQADSPEEMHSWIKAVS--GAIVAQRGPGRSAS 299
R N F I RTF+V DSP+E W++A+ + QR PG
Sbjct: 63 MKTERPRPNTFVIRCLQWTTVIERTFHV--DSPDEREEWMRAIQMVANSLKQRAPGEDPM 120
Query: 300 SEHPPGPSES 309
PS+S
Sbjct: 121 DYKCGSPSDS 130
>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
Length = 698
Score = 53.9 bits (128), Expect = 3e-07
Identities = 39/131 (29%), Positives = 60/131 (45%), Gaps = 12/131 (9%)
Query: 176 QSHLPYFTPKPPQDSAVIKAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVI 235
QS P P P + V+KAG+ KQ ++MKNW++R+F L + + Y+K + E +P I
Sbjct: 22 QSRSPGRMPCPHRLGPVLKAGWLKKQRSIMKNWQQRWFVLRGDQLFYYKDKDEIKPQGFI 81
Query: 236 PLKEVHKVQECKQSDIMMRDNLFEI-----------VTTSRTFYVQADSPEEMHSWIKAV 284
L+ +V E +LFEI + A S +M W++A+
Sbjct: 82 SLQGT-QVTELPPGPEDPGKHLFEISPGGAGEREKVPANPEALLLMASSQRDMEDWVQAI 140
Query: 285 SGAIVAQRGPG 295
I A G G
Sbjct: 141 RRVIWAPLGGG 151
>gi|156616273 pleckstrin [Homo sapiens]
Length = 350
Score = 53.5 bits (127), Expect = 3e-07
Identities = 33/102 (32%), Positives = 52/102 (50%), Gaps = 3/102 (2%)
Query: 193 IKAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPLKEVHKVQECKQSDIM 252
I+ GY VK+G+V WK + L E+ I ++K + + P +IPLK C+ D
Sbjct: 6 IREGYLVKKGSVFNTWKPMWVVLLEDGIEFYKKKSDNSPKGMIPLKGSTLTSPCQ--DFG 63
Query: 253 MRDNLFEIVTT-SRTFYVQADSPEEMHSWIKAVSGAIVAQRG 293
R +F+I TT + + QA EE +W++ + AI G
Sbjct: 64 KRMFVFKITTTKQQDHFFQAAFLEERDAWVRDIKKAIKCIEG 105
Score = 53.1 bits (126), Expect = 4e-07
Identities = 35/101 (34%), Positives = 53/101 (52%), Gaps = 5/101 (4%)
Query: 192 VIKAGYCVKQGAVMKNWKRRYFQLDENT--IGYFKSELEKEPLRVIPLK--EVHKVQECK 247
+IK G +KQG KNWK R F L E+ + Y+ ++PL I L+ V V+
Sbjct: 245 IIKQGCLLKQGHRRKNWKVRKFILREDPAYLHYYDPAGAEDPLGAIHLRGCVVTSVESNS 304
Query: 248 QSDIMMRDNLFEIVTTSRT-FYVQADSPEEMHSWIKAVSGA 287
+NLFEI+T +++QA +P+E WI+A+ A
Sbjct: 305 NGRKSEEENLFEIITADEVHYFLQAATPKERTEWIRAIQMA 345
>gi|7661880 centaurin beta1 [Homo sapiens]
Length = 740
Score = 53.5 bits (127), Expect = 3e-07
Identities = 65/283 (22%), Positives = 118/283 (41%), Gaps = 33/283 (11%)
Query: 90 YFLQANDQQDLVEWVNVLNKAIKITVPKQSDSQPNSDNLSRHGECGKKQVSYRTDIVGGV 149
Y LQ N +D ++ +++ +++ + + Q + LSR + YR ++ +
Sbjct: 173 YALQINVIEDKRKF-DIMEFVLRLVEAQATHFQQGHEELSRLSQ-------YRKELGAQL 224
Query: 150 PIITPTQKEEVNECGESIDRNNLKRSQSHLPYFTPKPPQ---DSAVIKAGYCVKQGA-VM 205
+ E + +++ ++ Q L P+P ++ G+ K+ +
Sbjct: 225 HQLVLNSAREKRD----MEQRHVLLKQKELGGEEPEPSLREGPGGLVMEGHLFKRASNAF 280
Query: 206 KNWKRRYFQLDENTIGYFKSELEKEPLRVIPLK-EVHKVQECKQSDIMMRDNLFEIVTTS 264
K W RR+F + N + Y K K+P+ V+ + V+ C S+ R FE+V+TS
Sbjct: 281 KTWSRRWFTIQSNQLVYQKKY--KDPVTVVVDDLRLCTVKLCPDSE---RRFCFEVVSTS 335
Query: 265 RTFYVQADSPEEMHSWIKAVSGAIVAQRGPGRSASSEHPPGPSESKHAFRPTNAATATSH 324
++ +QADS + W+ AV +I + R S P GP + +AAT S
Sbjct: 336 KSCLLQADSERLLQLWVSAVQSSIASAFSQARLDDS--PRGPGQGSGHLAIGSAATLGSG 393
Query: 325 STASRSNSLVSTFTMEKRGFYESLAKVKPGNFKVQTVSPREPA 367
A E G +A+V+ + Q REPA
Sbjct: 394 GMAR---------GREPGGVGHVVAQVQSVDGNAQCCDCREPA 427
>gi|195972859 cytohesin 2 isoform 2 [Homo sapiens]
Length = 399
Score = 53.5 bits (127), Expect = 3e-07
Identities = 30/113 (26%), Positives = 57/113 (50%), Gaps = 18/113 (15%)
Query: 194 KAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPL-----KEVHKVQECKQ 248
+ G+ +K G +K WKRR+F L +N + YF+ +KEP +IPL +EV ++
Sbjct: 262 REGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVDDPRKPNC 321
Query: 249 SDIMMRDNLFEIVTTSRT-------------FYVQADSPEEMHSWIKAVSGAI 288
++ + +N +++ +T + + A + EE WIK++ A+
Sbjct: 322 FELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAV 374
>gi|187608516 centaurin, beta 2 [Homo sapiens]
Length = 778
Score = 52.8 bits (125), Expect = 6e-07
Identities = 35/134 (26%), Positives = 65/134 (48%), Gaps = 8/134 (5%)
Query: 156 QKEEVNECGESIDRNNLKRSQSHLPYFTPKPPQDSAVIKAGYCVKQGA-VMKNWKRRYFQ 214
+K E+ + +I + + S L Y + ++ GY K+ + K W RR+F
Sbjct: 234 EKREMEQKHSTIQQKDFSSDDSKLEYNVDAA---NGIVMEGYLFKRASNAFKTWNRRWFS 290
Query: 215 LDENTIGYFKSELEKEPLRVIPLKEVHKVQECKQSDIMMRDNLFEIVTTSRTFYVQADSP 274
+ N + Y K + + P V+ + V+ C+ + R FE+V+ +++ +QADS
Sbjct: 291 IQNNQLVYQK-KFKDNPTVVVEDLRLCTVKHCEDIE---RRFCFEVVSPTKSCMLQADSE 346
Query: 275 EEMHSWIKAVSGAI 288
+ +WIKAV +I
Sbjct: 347 KLRQAWIKAVQTSI 360
>gi|18105042 GRB2-associated binding protein 2 isoform a [Homo
sapiens]
Length = 676
Score = 52.0 bits (123), Expect = 1e-06
Identities = 29/92 (31%), Positives = 52/92 (56%), Gaps = 21/92 (22%)
Query: 208 WKRRYFQL-------DENTIGYFKSELEKEPLRVIPLKEVHKVQECKQSDIMMRDN---- 256
WK+R+F L D + + Y+K++ K+PLR+I L C+Q D + N
Sbjct: 27 WKKRWFILRSGRMSGDPDVLEYYKNDHSKKPLRIINLNF------CEQVDAGLTFNKKEL 80
Query: 257 ----LFEIVTTSRTFYVQADSPEEMHSWIKAV 284
+F+I T+ RTFY+ A++ E+M+ W++++
Sbjct: 81 QDSFVFDIKTSERTFYLVAETEEDMNKWVQSI 112
>gi|93102364 SWAP-70 protein [Homo sapiens]
Length = 585
Score = 51.6 bits (122), Expect = 1e-06
Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 2/97 (2%)
Query: 192 VIKAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPLKEVHKVQECKQSDI 251
V+K GY +K+G KNW R+F L N I Y+ SE K+ I L E V+ D
Sbjct: 211 VLKQGYMMKKGHRRKNWTERWFVLKPNIISYYVSEDLKDKKGDILLDENCCVESLPDKD- 269
Query: 252 MMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVSGAI 288
+ LF + +TF + A ++ WI+A+ I
Sbjct: 270 -GKKCLFLVKCFDKTFEISASDKKKKQEWIQAIHSTI 305
>gi|21264592 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain
2 [Homo sapiens]
Length = 1704
Score = 51.6 bits (122), Expect = 1e-06
Identities = 30/100 (30%), Positives = 52/100 (52%), Gaps = 8/100 (8%)
Query: 193 IKAGYCVKQGAVMKN-WKRRYFQLDENTIGYFKSELEKEPLRVIPLKEVHKVQECKQSDI 251
+K+G+ K K +++R+ + D +I Y+ +E E +IPL + V+
Sbjct: 484 VKSGWLDKLSPQGKRMFQKRWVKFDGLSISYYNNEKEMYSKGIIPLSAISTVR------- 536
Query: 252 MMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVSGAIVAQ 291
+ DN FE+VTT RTF + + EE + WI + A+ +Q
Sbjct: 537 VQGDNKFEVVTTQRTFVFRVEKEEERNDWISILLNALKSQ 576
Score = 35.4 bits (80), Expect = 0.093
Identities = 43/140 (30%), Positives = 66/140 (47%), Gaps = 25/140 (17%)
Query: 156 QKEEVNECGESIDRNNLKRSQSHLPYFTPKPPQDSAVI---KAGYCVKQGAVMKNWKRRY 212
+KEE SI N LK SQS Q AV+ K GY +G +K +
Sbjct: 557 EKEEERNDWISILLNALK-SQS-------LTSQSQAVVTPEKCGYLELRG-----YKAKI 603
Query: 213 FQ-LDENTIGYFKSELEKEP---LRVIPLKEVHKVQECKQSDIMMRDNLFEIVTTSRTFY 268
F L N++ K+E + + + +IP+ V KQ D ++ + FEI+T R+F
Sbjct: 604 FTVLSGNSVWLCKNEQDFKSGLGITIIPMN----VANVKQVDRTVKQS-FEIITPYRSFS 658
Query: 269 VQADSPEEMHSWIKAVSGAI 288
A++ +E WI+AV +I
Sbjct: 659 FTAETEKEKQDWIEAVQQSI 678
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 50.4 bits (119), Expect = 3e-06
Identities = 29/99 (29%), Positives = 55/99 (55%), Gaps = 12/99 (12%)
Query: 193 IKAGYCVKQGA-----VMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPLKEVHKVQECK 247
+K G+ K+G +NWK+R+F L ++ + YF+++ E++ LK +V+ K
Sbjct: 1214 LKQGWLHKKGGGSSTLSRRNWKKRWFVLRQSKLMYFENDSEEK------LKGTVEVRTAK 1267
Query: 248 QS-DIMMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVS 285
+ D ++N +I+ RTF++ A+SPE+ W +S
Sbjct: 1268 EIIDNTTKENGIDIIMADRTFHLIAESPEDASQWFSVLS 1306
Score = 40.4 bits (93), Expect = 0.003
Identities = 19/54 (35%), Positives = 27/54 (50%)
Query: 228 EKEPLRVIPLKEVHKVQECKQSDIMMRDNLFEIVTTSRTFYVQADSPEEMHSWI 281
+ P + +V + SD R N F I+T +R + AD+PEEMH WI
Sbjct: 1323 QANPQNAVGTLDVGLIDSVCASDSPDRPNSFVIITANRVLHCNADTPEEMHHWI 1376
>gi|206597515 ArfGAP with RhoGAP domain, ankyrin repeat and PH
domain 1 isoform d [Homo sapiens]
Length = 1133
Score = 50.1 bits (118), Expect = 4e-06
Identities = 37/121 (30%), Positives = 61/121 (50%), Gaps = 16/121 (13%)
Query: 183 TPKPPQDSAVIKAGYCVK---QGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPLKE 239
TP P VIKAG+ K QG+ + +++R+ +LD + + YF S + R I +
Sbjct: 78 TPVTP----VIKAGWLDKNPPQGSYI--YQKRWVRLDTDHLRYFDSNKDAYSKRFISVA- 130
Query: 240 VHKVQECKQSDIMMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVSGAIVAQRGPGRSAS 299
C + D FE++T +RTF +A+S E W++A+ A+ QR R +S
Sbjct: 131 ------CISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSS 184
Query: 300 S 300
+
Sbjct: 185 A 185
Score = 35.8 bits (81), Expect = 0.071
Identities = 27/124 (21%), Positives = 51/124 (41%), Gaps = 5/124 (4%)
Query: 170 NNLKRSQSHLPYFTPKPPQDSAVIK---AGYCVKQGAVMKNWKRRYFQLDENTIGYFKSE 226
+++K + H P + K AG ++ + + RR+ L + + YF++E
Sbjct: 422 DSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENE 481
Query: 227 LEKEPLRVIPLKEVHKVQECKQSDIMMRDNLFEIVTTSRTFYV-QADSPEEMHSWIKAVS 285
P I E+ D ++ FE+ T Y+ +S E+ H W+K ++
Sbjct: 482 RAVTPNGEIRASEI-VCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIA 540
Query: 286 GAIV 289
A V
Sbjct: 541 KAFV 544
Score = 30.0 bits (66), Expect = 3.9
Identities = 13/31 (41%), Positives = 18/31 (58%)
Query: 258 FEIVTTSRTFYVQADSPEEMHSWIKAVSGAI 288
F++ T R F ADS E W++A+ GAI
Sbjct: 253 FDLTTPYRIFSFSADSELEKEQWLEAMQGAI 283
>gi|206597513 ArfGAP with RhoGAP domain, ankyrin repeat and PH
domain 1 isoform a [Homo sapiens]
Length = 1205
Score = 50.1 bits (118), Expect = 4e-06
Identities = 37/121 (30%), Positives = 61/121 (50%), Gaps = 16/121 (13%)
Query: 183 TPKPPQDSAVIKAGYCVK---QGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPLKE 239
TP P VIKAG+ K QG+ + +++R+ +LD + + YF S + R I +
Sbjct: 78 TPVTP----VIKAGWLDKNPPQGSYI--YQKRWVRLDTDHLRYFDSNKDAYSKRFISVA- 130
Query: 240 VHKVQECKQSDIMMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVSGAIVAQRGPGRSAS 299
C + D FE++T +RTF +A+S E W++A+ A+ QR R +S
Sbjct: 131 ------CISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSS 184
Query: 300 S 300
+
Sbjct: 185 A 185
Score = 35.8 bits (81), Expect = 0.071
Identities = 27/124 (21%), Positives = 51/124 (41%), Gaps = 5/124 (4%)
Query: 170 NNLKRSQSHLPYFTPKPPQDSAVIK---AGYCVKQGAVMKNWKRRYFQLDENTIGYFKSE 226
+++K + H P + K AG ++ + + RR+ L + + YF++E
Sbjct: 483 DSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENE 542
Query: 227 LEKEPLRVIPLKEVHKVQECKQSDIMMRDNLFEIVTTSRTFYV-QADSPEEMHSWIKAVS 285
P I E+ D ++ FE+ T Y+ +S E+ H W+K ++
Sbjct: 543 RAVTPNGEIRASEI-VCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIA 601
Query: 286 GAIV 289
A V
Sbjct: 602 KAFV 605
Score = 30.0 bits (66), Expect = 3.9
Identities = 13/31 (41%), Positives = 18/31 (58%)
Query: 258 FEIVTTSRTFYVQADSPEEMHSWIKAVSGAI 288
F++ T R F ADS E W++A+ GAI
Sbjct: 253 FDLTTPYRIFSFSADSELEKEQWLEAMQGAI 283
>gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain
1 isoform c [Homo sapiens]
Length = 1450
Score = 50.1 bits (118), Expect = 4e-06
Identities = 37/121 (30%), Positives = 61/121 (50%), Gaps = 16/121 (13%)
Query: 183 TPKPPQDSAVIKAGYCVK---QGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPLKE 239
TP P VIKAG+ K QG+ + +++R+ +LD + + YF S + R I +
Sbjct: 323 TPVTP----VIKAGWLDKNPPQGSYI--YQKRWVRLDTDHLRYFDSNKDAYSKRFISVA- 375
Query: 240 VHKVQECKQSDIMMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVSGAIVAQRGPGRSAS 299
C + D FE++T +RTF +A+S E W++A+ A+ QR R +S
Sbjct: 376 ------CISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSS 429
Query: 300 S 300
+
Sbjct: 430 A 430
Score = 35.8 bits (81), Expect = 0.071
Identities = 27/124 (21%), Positives = 51/124 (41%), Gaps = 5/124 (4%)
Query: 170 NNLKRSQSHLPYFTPKPPQDSAVIK---AGYCVKQGAVMKNWKRRYFQLDENTIGYFKSE 226
+++K + H P + K AG ++ + + RR+ L + + YF++E
Sbjct: 728 DSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENE 787
Query: 227 LEKEPLRVIPLKEVHKVQECKQSDIMMRDNLFEIVTTSRTFYV-QADSPEEMHSWIKAVS 285
P I E+ D ++ FE+ T Y+ +S E+ H W+K ++
Sbjct: 788 RAVTPNGEIRASEI-VCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIA 846
Query: 286 GAIV 289
A V
Sbjct: 847 KAFV 850
Score = 30.0 bits (66), Expect = 3.9
Identities = 13/31 (41%), Positives = 18/31 (58%)
Query: 258 FEIVTTSRTFYVQADSPEEMHSWIKAVSGAI 288
F++ T R F ADS E W++A+ GAI
Sbjct: 498 FDLTTPYRIFSFSADSELEKEQWLEAMQGAI 528
>gi|8670546 cytohesin 2 isoform 1 [Homo sapiens]
Length = 400
Score = 50.1 bits (118), Expect = 4e-06
Identities = 31/121 (25%), Positives = 59/121 (48%), Gaps = 23/121 (19%)
Query: 186 PPQDSAVIKAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPL-----KEV 240
P ++ ++K G G +K WKRR+F L +N + YF+ +KEP +IPL +EV
Sbjct: 260 PDREGWLLKLG-----GGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREV 314
Query: 241 HKVQECKQSDIMMRDNLFEIVTTSRT-------------FYVQADSPEEMHSWIKAVSGA 287
++ ++ + +N +++ +T + + A + EE WIK++ A
Sbjct: 315 DDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAA 374
Query: 288 I 288
+
Sbjct: 375 V 375
>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
sapiens]
Length = 748
Score = 49.7 bits (117), Expect = 5e-06
Identities = 34/112 (30%), Positives = 52/112 (46%), Gaps = 10/112 (8%)
Query: 193 IKAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPLKEVHKVQECKQSDIM 252
IK G+ KQG +K W R+F L + + YFK E E +PL I L +KV E ++
Sbjct: 21 IKCGWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLGTIFLPG-NKVSEHPCNEEN 79
Query: 253 MRDNLFEIV---------TTSRTFYVQADSPEEMHSWIKAVSGAIVAQRGPG 295
LFE+V ++ + A + +M W+K++ I G G
Sbjct: 80 PGKFLFEVVPGGDRDRMTANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGG 131
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,391,181
Number of Sequences: 37866
Number of extensions: 734553
Number of successful extensions: 2410
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 87
Number of HSP's successfully gapped in prelim test: 93
Number of HSP's that attempted gapping in prelim test: 2168
Number of HSP's gapped (non-prelim): 274
length of query: 404
length of database: 18,247,518
effective HSP length: 105
effective length of query: 299
effective length of database: 14,271,588
effective search space: 4267204812
effective search space used: 4267204812
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.