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Search of human proteins with 31377709
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo
sapiens]
(366 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo sapi... 751 0.0
gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo sap... 730 0.0
gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens] 668 0.0
gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens] 138 9e-33
gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens] 133 3e-31
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 130 2e-30
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] 130 2e-30
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens] 130 2e-30
gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens] 125 5e-29
gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens] 120 1e-27
gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens] 120 1e-27
gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo sapi... 120 1e-27
gi|41152235 ubiquitin specific protease 51 [Homo sapiens] 118 1e-26
gi|239742285 PREDICTED: hypothetical protein XP_002342486 [Homo ... 117 2e-26
gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens] 117 2e-26
gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens] 117 2e-26
gi|62243586 ubiquitin-specific protease 21 [Homo sapiens] 117 2e-26
gi|74027267 ubiquitin-specific protease 21 [Homo sapiens] 117 2e-26
gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens] 115 8e-26
gi|169217654 PREDICTED: similar to deubiquitinating enzyme DUB1 ... 115 8e-26
gi|113415482 PREDICTED: Ubiquitin carboxyl-terminal hydrolase 17... 114 1e-25
gi|239742291 PREDICTED: hypothetical protein XP_002342477 [Homo ... 114 2e-25
gi|239742289 PREDICTED: hypothetical protein XP_002342476 [Homo ... 114 2e-25
gi|239742278 PREDICTED: hypothetical protein XP_002342472 [Homo ... 114 2e-25
gi|239758075 PREDICTED: similar to deubiquitinating enzyme DUB1 ... 113 2e-25
gi|113415490 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 113 2e-25
gi|113415488 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 113 2e-25
gi|113415486 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 113 2e-25
gi|113415484 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 113 2e-25
gi|113415480 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 113 2e-25
>gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo
sapiens]
Length = 366
Score = 751 bits (1939), Expect = 0.0
Identities = 366/366 (100%), Positives = 366/366 (100%)
Query: 1 MTVRNIASICNMGTNASALEKDIGPEQFPINEHYFGLVNFGNTCYCNSVLQALYFCRPFR 60
MTVRNIASICNMGTNASALEKDIGPEQFPINEHYFGLVNFGNTCYCNSVLQALYFCRPFR
Sbjct: 1 MTVRNIASICNMGTNASALEKDIGPEQFPINEHYFGLVNFGNTCYCNSVLQALYFCRPFR 60
Query: 61 ENVLAYKAQQKKKENLLTCLADLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQD 120
ENVLAYKAQQKKKENLLTCLADLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQD
Sbjct: 61 ENVLAYKAQQKKKENLLTCLADLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQD 120
Query: 121 AHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNMNEPAENNKPELTWVHEIFQGTLTNET 180
AHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNMNEPAENNKPELTWVHEIFQGTLTNET
Sbjct: 121 AHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNMNEPAENNKPELTWVHEIFQGTLTNET 180
Query: 181 RCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQK 240
RCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQK
Sbjct: 181 RCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQK 240
Query: 241 RMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRLFNTSSDAVNLDRMYDLVA 300
RMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRLFNTSSDAVNLDRMYDLVA
Sbjct: 241 RMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRLFNTSSDAVNLDRMYDLVA 300
Query: 301 VVVHCGSGPNRGHYITIVKSHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYIL 360
VVVHCGSGPNRGHYITIVKSHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYIL
Sbjct: 301 VVVHCGSGPNRGHYITIVKSHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYIL 360
Query: 361 FYQSRE 366
FYQSRE
Sbjct: 361 FYQSRE 366
>gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo
sapiens]
Length = 359
Score = 730 bits (1884), Expect = 0.0
Identities = 355/357 (99%), Positives = 355/357 (99%)
Query: 10 CNMGTNASALEKDIGPEQFPINEHYFGLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQ 69
C GTNASALEKDIGPEQFPINEHYFGLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQ
Sbjct: 3 CFQGTNASALEKDIGPEQFPINEHYFGLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQ 62
Query: 70 QKKKENLLTCLADLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLL 129
QKKKENLLTCLADLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLL
Sbjct: 63 QKKKENLLTCLADLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLL 122
Query: 130 NTIADILQEEKKQEKQNGKLKNGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVS 189
NTIADILQEEKKQEKQNGKLKNGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVS
Sbjct: 123 NTIADILQEEKKQEKQNGKLKNGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVS 182
Query: 190 SKDEDFLDLSVDVEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPM 249
SKDEDFLDLSVDVEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPM
Sbjct: 183 SKDEDFLDLSVDVEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPM 242
Query: 250 ILALHLKRFKYMEQLHRYTKLSYRVVFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGP 309
ILALHLKRFKYMEQLHRYTKLSYRVVFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGP
Sbjct: 243 ILALHLKRFKYMEQLHRYTKLSYRVVFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGP 302
Query: 310 NRGHYITIVKSHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRE 366
NRGHYITIVKSHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRE
Sbjct: 303 NRGHYITIVKSHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRE 359
>gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens]
Length = 370
Score = 668 bits (1723), Expect = 0.0
Identities = 323/366 (88%), Positives = 340/366 (92%)
Query: 1 MTVRNIASICNMGTNASALEKDIGPEQFPINEHYFGLVNFGNTCYCNSVLQALYFCRPFR 60
MTV ASIC MG NASALEK+IGPEQFP+NEHYFGLVNFGNTCYCNSVLQALYFCRPFR
Sbjct: 5 MTVSKFASICTMGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFCRPFR 64
Query: 61 ENVLAYKAQQKKKENLLTCLADLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQD 120
E VLAYK+Q +KKE+LLTCLADLFHSIATQKKKVGVIPPKKFI+RLRKEN+LFDNYMQQD
Sbjct: 65 EKVLAYKSQPRKKESLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQD 124
Query: 121 AHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNMNEPAENNKPELTWVHEIFQGTLTNET 180
AHEFLNYLLNTIADILQEE+KQEKQNG+L NGN++ N+ P+ TWV EIFQGTLTNET
Sbjct: 125 AHEFLNYLLNTIADILQEERKQEKQNGRLPNGNIDNENNNSTPDPTWVDEIFQGTLTNET 184
Query: 181 RCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQK 240
RCL CET+SSKDEDFLDLSVDVEQNTSITHCLR FSNTETLCSE KYYCE C SKQEA K
Sbjct: 185 RCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHK 244
Query: 241 RMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRLFNTSSDAVNLDRMYDLVA 300
RM+VKKLPMILALHLKRFKYM+QLHRYTKLSYRVVFPLELRLFNTS DA N DRMYDLVA
Sbjct: 245 RMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVA 304
Query: 301 VVVHCGSGPNRGHYITIVKSHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYIL 360
VVVHCGSGPNRGHYI IVKSH FWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYIL
Sbjct: 305 VVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYIL 364
Query: 361 FYQSRE 366
FYQSR+
Sbjct: 365 FYQSRD 370
>gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens]
Length = 520
Score = 138 bits (347), Expect = 9e-33
Identities = 114/370 (30%), Positives = 161/370 (43%), Gaps = 64/370 (17%)
Query: 36 GLVNFGNTCYCNSVLQAL----YFCRPFRENVLAYKAQQKKKENLLTCLADLFHSIATQK 91
GL N GNTC+ N++LQ+L FC F+E + A + + K T +H+ +
Sbjct: 160 GLRNLGNTCFMNAILQSLSNIEQFCCYFKE-LPAVELRNGKTAGRRT-----YHTRSQGD 213
Query: 92 KKVGVIP------------------PKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIA 133
V ++ P+ + K F Y QQDAHEF+ YLL+ +
Sbjct: 214 NNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLH 273
Query: 134 DILQEEKKQEKQNGKLKNGNMNEPAENN---KPELTWVHEIFQGTLTNETRCLNCETVSS 190
LQ ++ L+ N A N T V IF G L NE CL C T S
Sbjct: 274 LELQGGFNGVSRSAILQE-NSTLSASNKCCINGASTVVTAIFGGILQNEVNCLICGTESR 332
Query: 191 KDEDFLDLSVDVEQN--------------TSITHCLRDFSNTETLCSEQKYYCETCCSKQ 236
K + FLDLS+D+ S+ CLR F++ E L + Y C C KQ
Sbjct: 333 KFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQ 392
Query: 237 EAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFP---LELRLFNTSSDAVNLD 293
++ K+ ++KLP +L LHLKRF + L K+ V FP L+++ + + +
Sbjct: 393 KSTKKFWIQKLPKVLCLHLKRFHWTAYLR--NKVDTYVEFPLRGLDMKCYLLEPENSGPE 450
Query: 294 R-MYDLVAVVVHCGSGPNRGHYITIVKSHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISK 352
+YDL AVVVH GSG GHY G W F+D V D + + +
Sbjct: 451 SCLYDLAAVVVHHGSGVGSGHYTAYATHEGRWFHFNDSTVTLTDEETVVK---------- 500
Query: 353 NSESGYILFY 362
YILFY
Sbjct: 501 --AKAYILFY 508
>gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens]
Length = 525
Score = 133 bits (334), Expect = 3e-31
Identities = 109/374 (29%), Positives = 166/374 (44%), Gaps = 74/374 (19%)
Query: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLA--YKAQQKKKENLLTC-LADLFHSIATQKK 92
GL+N GNTC+ N ++QAL R+ L+ ++ + + + L C ++ LF + +
Sbjct: 177 GLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHRCEMQSPSSCLVCEMSSLFQEFYSGHR 236
Query: 93 KVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNG 152
+ P K + + Y QQDAHEFL L D+L K + NGK
Sbjct: 237 SPHI--PYKLLHLVWTHARHLAGYEQQDAHEFLIAAL----DVLHRHCKGD-DNGK---- 285
Query: 153 NMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVD----------- 201
N P N + +IF G L ++ C C VS+ + F D+S+D
Sbjct: 286 KANNPNHCN----CIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPL 341
Query: 202 --------------VEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKL 247
V T++T CLR F+ E L S K C C S QE+ K++ +KKL
Sbjct: 342 SPGSEGNVVNGESHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKL 401
Query: 248 PMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRL---------------FNTSSDAVNL 292
P++ HLKRF++ +L R K++ V FPLEL + + +D++N
Sbjct: 402 PIVACFHLKRFEHSAKLRR--KITTYVSFPLELDMTPFMASSKESRMNGQYQQPTDSLNN 459
Query: 293 DRMYDLVAVVVHCGSGPNRGHYITIVKSH-GFWLLFDDDIVEKIDAQAIEEFYGLTSDIS 351
D Y L AVV H G+ GHY + ++ H W DD I+ K + + +
Sbjct: 460 DNKYSLFAVVNHQGT-LESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLD--------- 509
Query: 352 KNSESGYILFYQSR 365
GY+LFY +
Sbjct: 510 ---SEGYLLFYHKQ 520
>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 130 bits (327), Expect = 2e-30
Identities = 109/354 (30%), Positives = 164/354 (46%), Gaps = 48/354 (13%)
Query: 36 GLVNFGNTCYCNSVLQAL--------YFCRPF------RENVLAYKAQQKKKENLLTCLA 81
GL N GNTCY NS+LQ L YF R R N+L +K + ++ ++
Sbjct: 778 GLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK-- 835
Query: 82 DLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQE--- 138
A + I PK F + K ND F Y QQD+ E L +L++ + + L +
Sbjct: 836 ------ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADN 889
Query: 139 -EKKQEKQNGKLKNGNMNEPAENNKPEL--TWVHEIFQGTLTNETRCLNCETVSSKDEDF 195
++ +E+ N L + E A +L + + +FQG + +CL C S E F
Sbjct: 890 RKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAF 949
Query: 196 LDLSVDVEQNTSIT--HCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILAL 253
+ LS+ + + T CLR FS E L ++YC C +++++ K++ + KLP +L +
Sbjct: 950 MYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLV 1009
Query: 254 HLKRFKYMEQLHRYTKLSYRVVFPLE-LRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRG 312
HLKRF Y + + KL V FPLE L L N + Y+L +V H G G + G
Sbjct: 1010 HLKRFSYDGRWKQ--KLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYG-GLDGG 1066
Query: 313 HYITIVK--SHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQS 364
HY K + W FDD V I +++ S + YILFY S
Sbjct: 1067 HYTAYCKNAARQRWFKFDDHEVSDISVSSVK------------SSAAYILFYTS 1108
>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 130 bits (327), Expect = 2e-30
Identities = 109/354 (30%), Positives = 164/354 (46%), Gaps = 48/354 (13%)
Query: 36 GLVNFGNTCYCNSVLQAL--------YFCRPF------RENVLAYKAQQKKKENLLTCLA 81
GL N GNTCY NS+LQ L YF R R N+L +K + ++ ++
Sbjct: 778 GLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK-- 835
Query: 82 DLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQE--- 138
A + I PK F + K ND F Y QQD+ E L +L++ + + L +
Sbjct: 836 ------ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADN 889
Query: 139 -EKKQEKQNGKLKNGNMNEPAENNKPEL--TWVHEIFQGTLTNETRCLNCETVSSKDEDF 195
++ +E+ N L + E A +L + + +FQG + +CL C S E F
Sbjct: 890 RKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAF 949
Query: 196 LDLSVDVEQNTSIT--HCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILAL 253
+ LS+ + + T CLR FS E L ++YC C +++++ K++ + KLP +L +
Sbjct: 950 MYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLV 1009
Query: 254 HLKRFKYMEQLHRYTKLSYRVVFPLE-LRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRG 312
HLKRF Y + + KL V FPLE L L N + Y+L +V H G G + G
Sbjct: 1010 HLKRFSYDGRWKQ--KLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYG-GLDGG 1066
Query: 313 HYITIVK--SHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQS 364
HY K + W FDD V I +++ S + YILFY S
Sbjct: 1067 HYTAYCKNAARQRWFKFDDHEVSDISVSSVK------------SSAAYILFYTS 1108
>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 130 bits (327), Expect = 2e-30
Identities = 109/354 (30%), Positives = 164/354 (46%), Gaps = 48/354 (13%)
Query: 36 GLVNFGNTCYCNSVLQAL--------YFCRPF------RENVLAYKAQQKKKENLLTCLA 81
GL N GNTCY NS+LQ L YF R R N+L +K + ++ ++
Sbjct: 778 GLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK-- 835
Query: 82 DLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQE--- 138
A + I PK F + K ND F Y QQD+ E L +L++ + + L +
Sbjct: 836 ------ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADN 889
Query: 139 -EKKQEKQNGKLKNGNMNEPAENNKPEL--TWVHEIFQGTLTNETRCLNCETVSSKDEDF 195
++ +E+ N L + E A +L + + +FQG + +CL C S E F
Sbjct: 890 RKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAF 949
Query: 196 LDLSVDVEQNTSIT--HCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILAL 253
+ LS+ + + T CLR FS E L ++YC C +++++ K++ + KLP +L +
Sbjct: 950 MYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLV 1009
Query: 254 HLKRFKYMEQLHRYTKLSYRVVFPLE-LRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRG 312
HLKRF Y + + KL V FPLE L L N + Y+L +V H G G + G
Sbjct: 1010 HLKRFSYDGRWKQ--KLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYG-GLDGG 1066
Query: 313 HYITIVK--SHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQS 364
HY K + W FDD V I +++ S + YILFY S
Sbjct: 1067 HYTAYCKNAARQRWFKFDDHEVSDISVSSVK------------SSAAYILFYTS 1108
>gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens]
Length = 1316
Score = 125 bits (315), Expect = 5e-29
Identities = 100/337 (29%), Positives = 148/337 (43%), Gaps = 49/337 (14%)
Query: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTCLADLFHSIATQKKKV- 94
GL N GNTC+ N+ LQ L + P +L++ E+ TC A+ F + T + +
Sbjct: 112 GLQNLGNTCFANAALQCLTYTPPLANYMLSH-------EHSKTCHAEGFCMMCTMQAHIT 164
Query: 95 -------GVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNG 147
VI P I+ +R+ F Q+DAHEFL Y ++ + Q
Sbjct: 165 QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAM------------QKA 212
Query: 148 KLKNGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTS 207
L N + + T V +IF G L + +CLNC+ VS + +LD++++++ S
Sbjct: 213 CLNGSNK---LDRHTQATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQS 269
Query: 208 ITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRY 267
+ L F E L E Y C C A KR + + +L L LKRF
Sbjct: 270 VNKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTG---- 325
Query: 268 TKLSYRVVFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVK-SHGFWLL 326
K++ V +P L + S +Y L AV+VH G + GHY +K S+G W
Sbjct: 326 GKIAKDVKYPEYLDIRPYMSQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQ 385
Query: 327 FDDDIVEKIDAQAIEEFYGLTSDI-SKNSESGYILFY 362
+D IV TSDI S S+ Y+LFY
Sbjct: 386 MNDSIVS-------------TSDIRSVLSQQAYVLFY 409
>gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens]
Length = 1123
Score = 120 bits (302), Expect = 1e-27
Identities = 92/329 (27%), Positives = 143/329 (43%), Gaps = 33/329 (10%)
Query: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTCLADLFHSIATQKKKVG 95
GL N GNTC+ N+ +Q L + P +L+ + + + L + + I G
Sbjct: 123 GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHARSCHQGSFCMLCVMQNHIVQAFANSG 182
Query: 96 -VIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNM 154
I P FI L+K F Q+DAHEFL Y ++ + ++ NG K
Sbjct: 183 NAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYTIDAM--------QKACLNGCAKLDRQ 234
Query: 155 NEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRD 214
+ T VH+IF G L + +C C++VS + +LD+++++ Q +I L
Sbjct: 235 TQAT-------TLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIRQAANIVRALEL 287
Query: 215 FSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRV 274
F + L E Y C C K A KR + + +L L LKRF K++ V
Sbjct: 288 FVKADVLSGENAYMCAKCKKKVPASKRFTIHRTSNVLTLSLKRFANFSG----GKITKDV 343
Query: 275 VFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVK-SHGFWLLFDDDIVE 333
+P L + S MY L AV+VH G + GHY VK S+G W +D +V
Sbjct: 344 GYPEFLNIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVH 403
Query: 334 KIDAQAIEEFYGLTSDISKNSESGYILFY 362
+ + + ++ Y+LFY
Sbjct: 404 SSNVKVV------------LNQQAYVLFY 420
>gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens]
Length = 396
Score = 120 bits (302), Expect = 1e-27
Identities = 103/351 (29%), Positives = 163/351 (46%), Gaps = 44/351 (12%)
Query: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLA--YKAQQKKKENLLTCL----ADLFHSIAT 89
GL N GNTC+ NS+LQ L R R+ L Y N T L A L +I T
Sbjct: 59 GLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQTIWT 118
Query: 90 QKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKL 149
V+ P +F +++++ F Y QQDA EFL +LL+ + + + + K N +
Sbjct: 119 SSPN-DVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKSNPE- 176
Query: 150 KNGNMNEPAENNKPELTW----------VHEIFQGTLTNETRCLNCETVSSKDEDFLDLS 199
N++ ++ K W + ++F G L + C +C S+ + F DLS
Sbjct: 177 ---NLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLS 233
Query: 200 VDVEQN----TSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHL 255
+ + + ++ C+R F+ + L ++K C C ++ K+ +++ P IL LHL
Sbjct: 234 LPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHL 293
Query: 256 KRFKYMEQLHRYTKLSYRVVFPL-ELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHY 314
KRF E R +KL+ V FPL +L L +S+ N +Y+L AV H G+ GHY
Sbjct: 294 KRFS--ESRIRTSKLTTFVNFPLRDLDLREFASENTN-HAVYNLYAVSNHSGTTMG-GHY 349
Query: 315 ITIVKSHGF--WLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQ 363
+S G W F+D V + + + TSD Y+LFY+
Sbjct: 350 TAYCRSPGTGEWHTFNDSSVTPMSSSQVR-----TSD-------AYLLFYE 388
>gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo
sapiens]
Length = 605
Score = 120 bits (302), Expect = 1e-27
Identities = 103/351 (29%), Positives = 163/351 (46%), Gaps = 44/351 (12%)
Query: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLA--YKAQQKKKENLLTCL----ADLFHSIAT 89
GL N GNTC+ NS+LQ L R R+ L Y N T L A L +I T
Sbjct: 268 GLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQTIWT 327
Query: 90 QKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKL 149
V+ P +F +++++ F Y QQDA EFL +LL+ + + + + K N +
Sbjct: 328 SSPN-DVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKSNPE- 385
Query: 150 KNGNMNEPAENNKPELTW----------VHEIFQGTLTNETRCLNCETVSSKDEDFLDLS 199
N++ ++ K W + ++F G L + C +C S+ + F DLS
Sbjct: 386 ---NLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLS 442
Query: 200 VDVEQN----TSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHL 255
+ + + ++ C+R F+ + L ++K C C ++ K+ +++ P IL LHL
Sbjct: 443 LPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHL 502
Query: 256 KRFKYMEQLHRYTKLSYRVVFPL-ELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHY 314
KRF E R +KL+ V FPL +L L +S+ N +Y+L AV H G+ GHY
Sbjct: 503 KRFS--ESRIRTSKLTTFVNFPLRDLDLREFASENTN-HAVYNLYAVSNHSGTTMG-GHY 558
Query: 315 ITIVKSHGF--WLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQ 363
+S G W F+D V + + + TSD Y+LFY+
Sbjct: 559 TAYCRSPGTGEWHTFNDSSVTPMSSSQVR-----TSD-------AYLLFYE 597
>gi|41152235 ubiquitin specific protease 51 [Homo sapiens]
Length = 711
Score = 118 bits (295), Expect = 1e-26
Identities = 102/373 (27%), Positives = 163/373 (43%), Gaps = 73/373 (19%)
Query: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLA--YKAQQKKKENLLTC-LADLFHSIATQKK 92
GL+N GNTC+ N ++QAL ++ L+ +K L C ++ LFH++ + +
Sbjct: 364 GLINLGNTCFMNCIVQALTHIPLLKDFFLSDKHKCIMTSPSLCLVCEMSSLFHAMYSGSR 423
Query: 93 KVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNG 152
+ P K + + + Y QQDAHEFL +L D+L K + + N
Sbjct: 424 TPHI--PYKLLHLIWIHAEHLAGYRQQDAHEFLIAIL----DVLHRHSKDDSGGQEANNP 477
Query: 153 NMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDV--------EQ 204
N + +IF G L ++ C C +VS+ + D+S+D+ Q
Sbjct: 478 NCCNCI---------IDQIFTGGLQSDVTCQACHSVSTTIDPCWDISLDLPGSCATFDSQ 528
Query: 205 NT-----------------SITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKL 247
N S+T CL+ F+ E L S K C +C S QE+ K++ +KKL
Sbjct: 529 NPERADSTVSRDDHIPGIPSLTDCLQWFTRPEHLGSSAKIKCNSCQSYQESTKQLTMKKL 588
Query: 248 PMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRLF--------------NTSSDAVNLD 293
P++ HLKRF+++ + R K++ + FPLEL + +D V +
Sbjct: 589 PIVACFHLKRFEHVGKQRR--KINTFISFPLELDMTPFLASTKESRMKEGQPPTDCVPNE 646
Query: 294 RMYDLVAVVVHCGSGPNRGHYITIVKSH-GFWLLFDDDIVEKIDAQAIEEFYGLTSDISK 352
Y L AV+ H G+ GHY + ++ W DD I+ K IE+
Sbjct: 647 NKYSLFAVINHHGT-LESGHYTSFIRQQKDQWFSCDDAIITK---ATIEDLL-------- 694
Query: 353 NSESGYILFYQSR 365
GY+LFY +
Sbjct: 695 -YSEGYLLFYHKQ 706
>gi|239742285 PREDICTED: hypothetical protein XP_002342486 [Homo
sapiens]
Length = 559
Score = 117 bits (292), Expect = 2e-26
Identities = 91/331 (27%), Positives = 148/331 (44%), Gaps = 37/331 (11%)
Query: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTCLADLFHSIATQKKKVG 95
GL N GNTCY N+ LQ L + P +L+ + Q + L + I G
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 96 -VIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNM 154
VI P + ++ F Q+DAHEFL + ++ + KQ + K
Sbjct: 141 HVIQPSQALAAG------FHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSK------ 188
Query: 155 NEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRD 214
+ T +H+IF G ++ +CL+C +S + +LD+++D++ S+ L
Sbjct: 189 ---------DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQ 239
Query: 215 FSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRV 274
E L E Y+C C + A K + + +L L LKRF + K+ V
Sbjct: 240 LVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTG----NKIDKNV 295
Query: 275 VFP--LELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKS-HGFWLLFDD-- 329
+P L+++L+ + +++ L +Y L AV+VH G + GHY + VK+ G W DD
Sbjct: 296 QYPECLDMKLYMSQTNSGPL--VYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAE 353
Query: 330 ----DIVEKIDAQAIEEFYGLTSDISKNSES 356
I + QA FY S+ ++SES
Sbjct: 354 VTASSITSVLSQQAYVLFYIQKSEWERHSES 384
>gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens]
Length = 485
Score = 117 bits (292), Expect = 2e-26
Identities = 91/339 (26%), Positives = 149/339 (43%), Gaps = 46/339 (13%)
Query: 34 YFGLVNFGNTCYCNSVLQ----------ALYFCRPFRENVLAYKAQQKKKE----NLLTC 79
+ GL N G TCY N+ LQ ALY C + + Q++K+ +
Sbjct: 88 FVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEEKDYEPQTICEH 147
Query: 80 LADLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEE 139
L LF + ++ I P F+ L D QQDA EF ++ + D L ++
Sbjct: 148 LQYLFALLQNSNRRY--IDPSGFVKALG-----LDTGQQQDAQEFSKLFMSLLEDTLSKQ 200
Query: 140 KKQEKQNGKLKNGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLS 199
K + +N V + F G T C C S F +L
Sbjct: 201 KNPDVRN--------------------IVQQQFCGEYAYVTVCNQCGRESKLLSKFYELE 240
Query: 200 VDVEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFK 259
++++ + +T C+ +F E L + +Y+CE C SKQ A +++R+ LP L L L RF
Sbjct: 241 LNIQGHKQLTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFV 300
Query: 260 YMEQLHRYTKLSYRVVFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVK 319
+ Q KL+ + F E+ + +Y+L AV++H G GHYI VK
Sbjct: 301 FDRQTGHKKKLNTYIGFS-EILDMEPYVEHKGGSYVYELSAVLIHRGVSAYSGHYIAHVK 359
Query: 320 --SHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSES 356
G W F+D+ +EK++ + ++ G+ D+++ S+S
Sbjct: 360 DPQSGEWYKFNDEDIEKMEGKKLQ--LGIEEDLAEPSKS 396
>gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens]
Length = 1035
Score = 117 bits (292), Expect = 2e-26
Identities = 91/339 (26%), Positives = 149/339 (43%), Gaps = 46/339 (13%)
Query: 34 YFGLVNFGNTCYCNSVLQ----------ALYFCRPFRENVLAYKAQQKKKE----NLLTC 79
+ GL N G TCY N+ LQ ALY C + + Q++K+ +
Sbjct: 88 FVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEEKDYEPQTICEH 147
Query: 80 LADLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEE 139
L LF + ++ I P F+ L D QQDA EF ++ + D L ++
Sbjct: 148 LQYLFALLQNSNRRY--IDPSGFVKALG-----LDTGQQQDAQEFSKLFMSLLEDTLSKQ 200
Query: 140 KKQEKQNGKLKNGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLS 199
K + +N V + F G T C C S F +L
Sbjct: 201 KNPDVRN--------------------IVQQQFCGEYAYVTVCNQCGRESKLLSKFYELE 240
Query: 200 VDVEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFK 259
++++ + +T C+ +F E L + +Y+CE C SKQ A +++R+ LP L L L RF
Sbjct: 241 LNIQGHKQLTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFV 300
Query: 260 YMEQLHRYTKLSYRVVFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVK 319
+ Q KL+ + F E+ + +Y+L AV++H G GHYI VK
Sbjct: 301 FDRQTGHKKKLNTYIGFS-EILDMEPYVEHKGGSYVYELSAVLIHRGVSAYSGHYIAHVK 359
Query: 320 --SHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSES 356
G W F+D+ +EK++ + ++ G+ D+++ S+S
Sbjct: 360 DPQSGEWYKFNDEDIEKMEGKKLQ--LGIEEDLAEPSKS 396
>gi|62243586 ubiquitin-specific protease 21 [Homo sapiens]
Length = 565
Score = 117 bits (292), Expect = 2e-26
Identities = 100/365 (27%), Positives = 158/365 (43%), Gaps = 54/365 (14%)
Query: 34 YFGLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQK-----KKENLLTCLADLFHSIA 88
+ GL N GNTC+ N+VLQ L RP R+ L +Q+ + + L AD+ ++
Sbjct: 211 HVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGGGRAQELTEAFADVIGAL- 269
Query: 89 TQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGK 148
+ P +F + +K F Y QQDA EFL L+ + L+ ++ +
Sbjct: 270 WHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLH--LEINRRGRRAPPI 327
Query: 149 LKNGNMNEP-------------AENNKPELTW----------VHEIFQGTLTNETRCLNC 185
L NG + P +++++ L W + ++F G L + +C C
Sbjct: 328 LANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQAC 387
Query: 186 ETVSSKDEDFLDLSVDVEQN------TSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQ 239
S+ E F DLS+ + + S+ C F+ E L SE C+ C K +
Sbjct: 388 GYRSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFNLFTKEEELESENAPVCDRCRQKTRST 447
Query: 240 KRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLE-LRLFNTSSDAVNLDRMYDL 298
K++ V++ P IL LHL RF K S V FPL+ L L + +SD +Y L
Sbjct: 448 KKLTVQRFPRILVLHLNRFS--ASRGSIKKSSVGVDFPLQRLSLGDFASDKAG-SPVYQL 504
Query: 299 VAVVVHCGSGPNRGHYITIVKSHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGY 358
A+ H GS + GHY + + W +++D V + + S GY
Sbjct: 505 YALCNHSGS-VHYGHYTALCRCQTGWHVYNDSRVSPVSENQVA------------SSEGY 551
Query: 359 ILFYQ 363
+LFYQ
Sbjct: 552 VLFYQ 556
>gi|74027267 ubiquitin-specific protease 21 [Homo sapiens]
Length = 565
Score = 117 bits (292), Expect = 2e-26
Identities = 100/365 (27%), Positives = 158/365 (43%), Gaps = 54/365 (14%)
Query: 34 YFGLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQK-----KKENLLTCLADLFHSIA 88
+ GL N GNTC+ N+VLQ L RP R+ L +Q+ + + L AD+ ++
Sbjct: 211 HVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGGGRAQELTEAFADVIGAL- 269
Query: 89 TQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGK 148
+ P +F + +K F Y QQDA EFL L+ + L+ ++ +
Sbjct: 270 WHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLH--LEINRRGRRAPPI 327
Query: 149 LKNGNMNEP-------------AENNKPELTW----------VHEIFQGTLTNETRCLNC 185
L NG + P +++++ L W + ++F G L + +C C
Sbjct: 328 LANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQAC 387
Query: 186 ETVSSKDEDFLDLSVDVEQN------TSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQ 239
S+ E F DLS+ + + S+ C F+ E L SE C+ C K +
Sbjct: 388 GYRSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFNLFTKEEELESENAPVCDRCRQKTRST 447
Query: 240 KRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLE-LRLFNTSSDAVNLDRMYDL 298
K++ V++ P IL LHL RF K S V FPL+ L L + +SD +Y L
Sbjct: 448 KKLTVQRFPRILVLHLNRFS--ASRGSIKKSSVGVDFPLQRLSLGDFASDKAG-SPVYQL 504
Query: 299 VAVVVHCGSGPNRGHYITIVKSHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGY 358
A+ H GS + GHY + + W +++D V + + S GY
Sbjct: 505 YALCNHSGS-VHYGHYTALCRCQTGWHVYNDSRVSPVSENQVA------------SSEGY 551
Query: 359 ILFYQ 363
+LFYQ
Sbjct: 552 VLFYQ 556
>gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens]
Length = 438
Score = 115 bits (287), Expect = 8e-26
Identities = 101/373 (27%), Positives = 161/373 (43%), Gaps = 73/373 (19%)
Query: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLA--YKAQQKKKENLLTC-LADLFHSIATQKK 92
GL+N GNTC+ N ++QAL R+ L+ ++ + E L C ++ LF + +
Sbjct: 79 GLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSSLFRELYSGNP 138
Query: 93 KVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNG 152
V P K + + Y QQDAHEFL L D+L K
Sbjct: 139 SPHV--PYKLLHLVWIHARHLAGYRQQDAHEFLIAAL----DVLHRH---------CKGD 183
Query: 153 NMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQN------- 205
++ + A N + +IF G L ++ C C VS+ + D+S+D+ +
Sbjct: 184 DVGKAANNPNHCNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPM 243
Query: 206 -----------------TSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLP 248
T++T CLR F+ E L S K C +C S QE+ K++ + KLP
Sbjct: 244 SPGRESSVNGESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLP 303
Query: 249 MILALHLKRFKYMEQLHRYTKLSYRVVFPLELRL--FNTSS-------------DAVNLD 293
++ H KRF++ + R K++ + FPLEL + F SS ++ N +
Sbjct: 304 VVACFHFKRFEHSAKQRR--KITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNE 361
Query: 294 RMYDLVAVVVHCGSGPNRGHYITIVKSH-GFWLLFDDDIVEKIDAQAIEEFYGLTSDISK 352
Y L AVV H G+ GHY + ++ H W DD ++ K + + +
Sbjct: 362 NKYSLFAVVNHQGT-LESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLD---------- 410
Query: 353 NSESGYILFYQSR 365
GY+LFY +
Sbjct: 411 --SEGYLLFYHKQ 421
>gi|169217654 PREDICTED: similar to deubiquitinating enzyme DUB1
[Homo sapiens]
Length = 530
Score = 115 bits (287), Expect = 8e-26
Identities = 90/329 (27%), Positives = 143/329 (43%), Gaps = 33/329 (10%)
Query: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTCLADLFHSIATQKKKVG 95
GL N GNTCY N+ LQ L + P +L+ + Q + L + I G
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 96 -VIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNM 154
VI P + ++ F Q+DAHEFL + ++ + KQ
Sbjct: 141 HVIQPSQALAAG------FHRGKQEDAHEFLMFTVDAMKKACLPGHKQ------------ 182
Query: 155 NEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRD 214
A+++ + T +H+IF G ++ +CL+C +S + +LD+++D++ S+ L
Sbjct: 183 ---ADHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQ 239
Query: 215 FSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRV 274
E L E Y+C C + A K + + +L L LKRF + K++ V
Sbjct: 240 LVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTG----NKIAKNV 295
Query: 275 VFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKS-HGFWLLFDD---- 329
+P L + S +Y L AV+VH G + GHY + VK+ G W DD
Sbjct: 296 QYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVT 355
Query: 330 --DIVEKIDAQAIEEFYGLTSDISKNSES 356
I + QA FY S+ ++SES
Sbjct: 356 ASSITSVLSQQAYVLFYIQKSEWERHSES 384
>gi|113415482 PREDICTED: Ubiquitin carboxyl-terminal hydrolase
17-like protein 5 [Homo sapiens]
Length = 530
Score = 114 bits (286), Expect = 1e-25
Identities = 90/329 (27%), Positives = 142/329 (43%), Gaps = 33/329 (10%)
Query: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTCLADLFHSIATQKKKVG 95
GL N GNTCY N+ LQ L + P +L+ + Q + L + I G
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 96 -VIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNM 154
VI P + ++ F Q+DAHEFL + ++ + KQ + K
Sbjct: 141 HVIQPSQALAAG------FHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSK------ 188
Query: 155 NEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRD 214
+ T +H+IF G ++ +CL+C +S + +LD+++D++ S+ L
Sbjct: 189 ---------DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQ 239
Query: 215 FSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRV 274
+ E L E Y+C C + A K + + +L L LKRF + K++ V
Sbjct: 240 LAKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTG----NKIAKNV 295
Query: 275 VFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKS-HGFWLLFDD---- 329
+P L + S +Y L AV+VH G + GHY + VK+ G W DD
Sbjct: 296 QYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVT 355
Query: 330 --DIVEKIDAQAIEEFYGLTSDISKNSES 356
I + QA FY S+ ++SES
Sbjct: 356 ASSITSVLSQQAYVLFYIQKSEWERHSES 384
>gi|239742291 PREDICTED: hypothetical protein XP_002342477 [Homo
sapiens]
Length = 530
Score = 114 bits (284), Expect = 2e-25
Identities = 90/329 (27%), Positives = 141/329 (42%), Gaps = 33/329 (10%)
Query: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTCLADLFHSIATQKKKVG 95
GL N GNTCY N+ LQ L + P +L+ + Q + L + I G
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 96 -VIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNM 154
VI P + ++ F Q+DAHEFL + ++ + KQ + K
Sbjct: 141 HVIQPSQALAAG------FHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSK------ 188
Query: 155 NEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRD 214
+ T +H+IF G ++ +CL+C +S + +LD+++D++ S+ L
Sbjct: 189 ---------DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQ 239
Query: 215 FSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRV 274
E L E Y+C C + A K + + +L L LKRF + K++ V
Sbjct: 240 LVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTG----NKIAKNV 295
Query: 275 VFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKS-HGFWLLFDD---- 329
+P L + S +Y L AV+VH G + GHY + VK+ G W DD
Sbjct: 296 QYPECLDMQPYMSQTNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVT 355
Query: 330 --DIVEKIDAQAIEEFYGLTSDISKNSES 356
I + QA FY S+ ++SES
Sbjct: 356 ASSITSVLSQQAYVLFYIQKSEWERHSES 384
>gi|239742289 PREDICTED: hypothetical protein XP_002342476 [Homo
sapiens]
Length = 530
Score = 114 bits (284), Expect = 2e-25
Identities = 90/329 (27%), Positives = 141/329 (42%), Gaps = 33/329 (10%)
Query: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTCLADLFHSIATQKKKVG 95
GL N GNTCY N+ LQ L + P +L+ + Q + L + I G
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 96 -VIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNM 154
VI P + ++ F Q+DAHEFL + ++ + KQ + K
Sbjct: 141 HVIQPSQALAAG------FHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSK------ 188
Query: 155 NEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRD 214
+ T +H+IF G ++ +CL+C +S + +LD+++D++ S+ L
Sbjct: 189 ---------DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQ 239
Query: 215 FSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRV 274
E L E Y+C C + A K + + +L L LKRF + K++ V
Sbjct: 240 LVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTG----NKIAKNV 295
Query: 275 VFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKS-HGFWLLFDD---- 329
+P L + S +Y L AV+VH G + GHY + VK+ G W DD
Sbjct: 296 QYPECLDMQPYMSQTNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVT 355
Query: 330 --DIVEKIDAQAIEEFYGLTSDISKNSES 356
I + QA FY S+ ++SES
Sbjct: 356 ASSITSVLSQQAYVLFYIQKSEWERHSES 384
>gi|239742278 PREDICTED: hypothetical protein XP_002342472 [Homo
sapiens]
Length = 530
Score = 114 bits (284), Expect = 2e-25
Identities = 90/329 (27%), Positives = 141/329 (42%), Gaps = 33/329 (10%)
Query: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTCLADLFHSIATQKKKVG 95
GL N GNTCY N+ LQ L + P +L+ + Q + L + I G
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 96 -VIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNM 154
VI P + ++ F Q+DAHEFL + ++ + KQ + K
Sbjct: 141 HVIQPSQALAAG------FHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSK------ 188
Query: 155 NEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRD 214
+ T +H+IF G ++ +CL+C +S + +LD+++D++ S+ L
Sbjct: 189 ---------DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQ 239
Query: 215 FSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRV 274
E L E Y+C C + A K + + +L L LKRF + K++ V
Sbjct: 240 LVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTG----NKIAKNV 295
Query: 275 VFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKS-HGFWLLFDD---- 329
+P L + S +Y L AV+VH G + GHY + VK+ G W DD
Sbjct: 296 QYPECLDMQPYMSQTNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVT 355
Query: 330 --DIVEKIDAQAIEEFYGLTSDISKNSES 356
I + QA FY S+ ++SES
Sbjct: 356 ASSITSVLSQQAYVLFYIQKSEWERHSES 384
>gi|239758075 PREDICTED: similar to deubiquitinating enzyme DUB1
[Homo sapiens]
Length = 530
Score = 113 bits (283), Expect = 2e-25
Identities = 90/329 (27%), Positives = 141/329 (42%), Gaps = 33/329 (10%)
Query: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTCLADLFHSIATQKKKVG 95
GL N GNTCY N+ LQ L + P +L+ + Q + L + I G
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 96 -VIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNM 154
VI P + ++ F Q+DAHEFL + ++ + KQ + K
Sbjct: 141 HVIQPSQALAAG------FHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSK------ 188
Query: 155 NEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRD 214
+ T +H+IF G ++ +CL+C +S + +LD+++D++ S+ L
Sbjct: 189 ---------DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQ 239
Query: 215 FSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRV 274
E L E Y+C C + A K + + +L L LKRF + K++ V
Sbjct: 240 LVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTG----NKIAKNV 295
Query: 275 VFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKS-HGFWLLFDD---- 329
+P L + S +Y L AV+VH G + GHY + VK+ G W DD
Sbjct: 296 QYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVT 355
Query: 330 --DIVEKIDAQAIEEFYGLTSDISKNSES 356
I + QA FY S+ ++SES
Sbjct: 356 ASSITSVLSQQAYVLFYIQKSEWERHSES 384
>gi|113415490 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
sapiens]
Length = 530
Score = 113 bits (283), Expect = 2e-25
Identities = 90/329 (27%), Positives = 141/329 (42%), Gaps = 33/329 (10%)
Query: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTCLADLFHSIATQKKKVG 95
GL N GNTCY N+ LQ L + P +L+ + Q + L + I G
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 96 -VIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNM 154
VI P + ++ F Q+DAHEFL + ++ + KQ + K
Sbjct: 141 HVIQPSQALAAG------FHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSK------ 188
Query: 155 NEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRD 214
+ T +H+IF G ++ +CL+C +S + +LD+++D++ S+ L
Sbjct: 189 ---------DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQ 239
Query: 215 FSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRV 274
E L E Y+C C + A K + + +L L LKRF + K++ V
Sbjct: 240 LVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTG----NKIAKNV 295
Query: 275 VFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKS-HGFWLLFDD---- 329
+P L + S +Y L AV+VH G + GHY + VK+ G W DD
Sbjct: 296 QYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVT 355
Query: 330 --DIVEKIDAQAIEEFYGLTSDISKNSES 356
I + QA FY S+ ++SES
Sbjct: 356 ASSITSVLSQQAYVLFYIQKSEWERHSES 384
>gi|113415488 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
sapiens]
Length = 530
Score = 113 bits (283), Expect = 2e-25
Identities = 90/329 (27%), Positives = 141/329 (42%), Gaps = 33/329 (10%)
Query: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTCLADLFHSIATQKKKVG 95
GL N GNTCY N+ LQ L + P +L+ + Q + L + I G
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 96 -VIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNM 154
VI P + ++ F Q+DAHEFL + ++ + KQ + K
Sbjct: 141 HVIQPSQALAAG------FHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSK------ 188
Query: 155 NEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRD 214
+ T +H+IF G ++ +CL+C +S + +LD+++D++ S+ L
Sbjct: 189 ---------DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQ 239
Query: 215 FSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRV 274
E L E Y+C C + A K + + +L L LKRF + K++ V
Sbjct: 240 LVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTG----NKIAKNV 295
Query: 275 VFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKS-HGFWLLFDD---- 329
+P L + S +Y L AV+VH G + GHY + VK+ G W DD
Sbjct: 296 QYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVT 355
Query: 330 --DIVEKIDAQAIEEFYGLTSDISKNSES 356
I + QA FY S+ ++SES
Sbjct: 356 ASSITSVLSQQAYVLFYIQKSEWERHSES 384
>gi|113415486 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
sapiens]
Length = 530
Score = 113 bits (283), Expect = 2e-25
Identities = 90/329 (27%), Positives = 141/329 (42%), Gaps = 33/329 (10%)
Query: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTCLADLFHSIATQKKKVG 95
GL N GNTCY N+ LQ L + P +L+ + Q + L + I G
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 96 -VIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNM 154
VI P + ++ F Q+DAHEFL + ++ + KQ + K
Sbjct: 141 HVIQPSQALAAG------FHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSK------ 188
Query: 155 NEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRD 214
+ T +H+IF G ++ +CL+C +S + +LD+++D++ S+ L
Sbjct: 189 ---------DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQ 239
Query: 215 FSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRV 274
E L E Y+C C + A K + + +L L LKRF + K++ V
Sbjct: 240 LVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTG----NKIAKNV 295
Query: 275 VFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKS-HGFWLLFDD---- 329
+P L + S +Y L AV+VH G + GHY + VK+ G W DD
Sbjct: 296 QYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVT 355
Query: 330 --DIVEKIDAQAIEEFYGLTSDISKNSES 356
I + QA FY S+ ++SES
Sbjct: 356 ASSITSVLSQQAYVLFYIQKSEWERHSES 384
>gi|113415484 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
sapiens]
Length = 530
Score = 113 bits (283), Expect = 2e-25
Identities = 90/329 (27%), Positives = 141/329 (42%), Gaps = 33/329 (10%)
Query: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTCLADLFHSIATQKKKVG 95
GL N GNTCY N+ LQ L + P +L+ + Q + L + I G
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 96 -VIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNM 154
VI P + ++ F Q+DAHEFL + ++ + KQ + K
Sbjct: 141 HVIQPSQALAAG------FHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSK------ 188
Query: 155 NEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRD 214
+ T +H+IF G ++ +CL+C +S + +LD+++D++ S+ L
Sbjct: 189 ---------DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQ 239
Query: 215 FSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRV 274
E L E Y+C C + A K + + +L L LKRF + K++ V
Sbjct: 240 LVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTG----NKIAKNV 295
Query: 275 VFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKS-HGFWLLFDD---- 329
+P L + S +Y L AV+VH G + GHY + VK+ G W DD
Sbjct: 296 QYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVT 355
Query: 330 --DIVEKIDAQAIEEFYGLTSDISKNSES 356
I + QA FY S+ ++SES
Sbjct: 356 ASSITSVLSQQAYVLFYIQKSEWERHSES 384
>gi|113415480 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
sapiens]
Length = 530
Score = 113 bits (283), Expect = 2e-25
Identities = 90/329 (27%), Positives = 141/329 (42%), Gaps = 33/329 (10%)
Query: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTCLADLFHSIATQKKKVG 95
GL N GNTCY N+ LQ L + P +L+ + Q + L + I G
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 96 -VIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNM 154
VI P + ++ F Q+DAHEFL + ++ + KQ + K
Sbjct: 141 HVIQPSQALAAG------FHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSK------ 188
Query: 155 NEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRD 214
+ T +H+IF G ++ +CL+C +S + +LD+++D++ S+ L
Sbjct: 189 ---------DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQ 239
Query: 215 FSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRV 274
E L E Y+C C + A K + + +L L LKRF + K++ V
Sbjct: 240 LVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTG----NKIAKNV 295
Query: 275 VFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKS-HGFWLLFDD---- 329
+P L + S +Y L AV+VH G + GHY + VK+ G W DD
Sbjct: 296 QYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVT 355
Query: 330 --DIVEKIDAQAIEEFYGLTSDISKNSES 356
I + QA FY S+ ++SES
Sbjct: 356 ASSITSVLSQQAYVLFYIQKSEWERHSES 384
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,640,745
Number of Sequences: 37866
Number of extensions: 597310
Number of successful extensions: 2081
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 108
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 1654
Number of HSP's gapped (non-prelim): 242
length of query: 366
length of database: 18,247,518
effective HSP length: 104
effective length of query: 262
effective length of database: 14,309,454
effective search space: 3749076948
effective search space used: 3749076948
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.