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Search of human proteins with 31377595
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
(953 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 1924 0.0
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 134 5e-31
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 116 1e-25
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 115 2e-25
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 112 1e-24
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 103 8e-22
gi|20070262 TNF receptor-associated factor 3 interacting protein... 101 3e-21
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 100 8e-21
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 99 1e-20
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 98 3e-20
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 98 3e-20
gi|56549694 enabled homolog isoform a [Homo sapiens] 98 4e-20
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 97 7e-20
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 97 9e-20
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 96 2e-19
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 95 3e-19
gi|39930375 enabled homolog isoform b [Homo sapiens] 94 5e-19
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 93 1e-18
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 92 2e-18
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 90 9e-18
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 88 4e-17
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 87 6e-17
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 87 6e-17
gi|167234419 thyroid hormone receptor associated protein 3 [Homo... 87 1e-16
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 86 1e-16
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 86 1e-16
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 86 2e-16
gi|50053795 eukaryotic translation initiation factor 4B [Homo sa... 85 4e-16
gi|28559039 mediator complex subunit 1 [Homo sapiens] 84 5e-16
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 84 8e-16
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 1924 bits (4983), Expect = 0.0
Identities = 953/953 (100%), Positives = 953/953 (100%)
Query: 1 MDVAESPERDPHSPEDEEQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQ 60
MDVAESPERDPHSPEDEEQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQ
Sbjct: 1 MDVAESPERDPHSPEDEEQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQ 60
Query: 61 EEEDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVT 120
EEEDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVT
Sbjct: 61 EEEDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVT 120
Query: 121 RELDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESL 180
RELDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESL
Sbjct: 121 RELDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESL 180
Query: 181 EAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKGNCTWGMNCRF 240
EAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKGNCTWGMNCRF
Sbjct: 181 EAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKGNCTWGMNCRF 240
Query: 241 IHPGVNDKGNYSLITKADPFPPNGAPPLGPHPLMPANPWGGPVVDEILPPPPPEPPTESA 300
IHPGVNDKGNYSLITKADPFPPNGAPPLGPHPLMPANPWGGPVVDEILPPPPPEPPTESA
Sbjct: 241 IHPGVNDKGNYSLITKADPFPPNGAPPLGPHPLMPANPWGGPVVDEILPPPPPEPPTESA 300
Query: 301 WERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVR 360
WERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVR
Sbjct: 301 WERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVR 360
Query: 361 DTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERE 420
DTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERE
Sbjct: 361 DTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERE 420
Query: 421 RERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEK 480
RERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEK
Sbjct: 421 RERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEK 480
Query: 481 GKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARR 540
GKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARR
Sbjct: 481 GKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARR 540
Query: 541 RRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSR 600
RRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSR
Sbjct: 541 RRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSR 600
Query: 601 SFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPT 660
SFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPT
Sbjct: 601 SFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPT 660
Query: 661 KPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSS 720
KPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSS
Sbjct: 661 KPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSS 720
Query: 721 SSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPK 780
SSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPK
Sbjct: 721 SSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPK 780
Query: 781 SAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDR 840
SAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDR
Sbjct: 781 SAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDR 840
Query: 841 QSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSS 900
QSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSS
Sbjct: 841 QSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSS 900
Query: 901 KVTSVPGKASDPGAASTKSGKASTLSRREELLKQLKAVEDAIARKRAKIPGKA 953
KVTSVPGKASDPGAASTKSGKASTLSRREELLKQLKAVEDAIARKRAKIPGKA
Sbjct: 901 KVTSVPGKASDPGAASTKSGKASTLSRREELLKQLKAVEDAIARKRAKIPGKA 953
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 134 bits (336), Expect = 5e-31
Identities = 130/521 (24%), Positives = 202/521 (38%), Gaps = 77/521 (14%)
Query: 402 RERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRD 461
+E+ ++++ +++ + E++ RE+R+R R R R +RR RER +
Sbjct: 138 QEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSH 197
Query: 462 EKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRR 521
+ +HR + R EK + P P+P + EP +EA +T +K P +
Sbjct: 198 SRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPK 257
Query: 522 SKSPKKKLGVSVSPSRARRRRKTSASSASASNS-SRSSSRSSSYSGSGSSRSRSRSSSYS 580
SP+K + + + + KT S S S S SR+ SRS S++ R RSRS SYS
Sbjct: 258 EPSPEK------NSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHT-RPRRRHRSRSRSYS 310
Query: 581 SYSSRSSRHSSFSGSRSRSRSFSSSP----SPSPTPSPHRPSIRTKGEPAPPPGKAGEKS 636
S R R+ R P S SP R S G +
Sbjct: 311 PRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSP 370
Query: 637 VKKPAP-PPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSY 695
KKP +PP+ T+ +P P PR R PA PP+ R +
Sbjct: 371 PKKPPKRTSSPPRKTRRLSPSASP-----PRRRHRPSPPATPPPKTR------------H 413
Query: 696 SGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKE 755
S + +S S VS TS + H S SPAP + E
Sbjct: 414 SPTPQQSNRTRKSRVSVSPGRTSGKVTKH------------KGTEKRESPSPAPKPRKVE 461
Query: 756 KGKSKKEDGVK----EEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFV 811
+S+++ G K + ++R + + + +G SS + P+++
Sbjct: 462 LSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHV--------- 512
Query: 812 AHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKP 871
K + G R+R+ PS SP P KR + RG R R SP P
Sbjct: 513 -----------KNGEVGRRRRHSPSRS--ASPSPRKRQKETSPRGRRRR-------SPSP 552
Query: 872 ERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGKASDP 912
R + S +PA P R+R +P + + S P + P
Sbjct: 553 PPTRRRRSPSPAPPPRRRRTPTPPPR--RRTPSPPPRRRSP 591
Score = 96.3 bits (238), Expect = 1e-19
Identities = 173/784 (22%), Positives = 280/784 (35%), Gaps = 125/784 (15%)
Query: 43 VRASDLEDEESAARGPSQEEEDNHSDEEDRASEPKSQDQDSEVNELSRGPT----SSPCE 98
++ +E E+ A+ E++D EE +S K + S SR P+ SSP
Sbjct: 131 IKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVR 190
Query: 99 EEGDEGE--------EDRTSDLRDEASSVTRELDEHELDYDE-------------EVPE- 136
E + R+ E T EL E + E +VP+
Sbjct: 191 RERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKP 250
Query: 137 EPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESLEAAKEKKKEDDDGEID 196
EP P +E EK ++ ++EK + PR ++ +S S + +++
Sbjct: 251 EPIPEPKEPSPEK-NSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSR-- 307
Query: 197 DGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKGNCTWGMNCRFIHP-----------GV 245
+ PS R+ RP P R + + R P
Sbjct: 308 ---------SYSPRRRPSPRR-RPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSG 357
Query: 246 NDKGNYSLITKADPFPPNGAPPLGPHPLMPANPWGGPVVDEILPPPPPEPPTESAWERGL 305
+ + S +++ P P P +P P P PP PP ++
Sbjct: 358 SSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKT------ 411
Query: 306 RHAKEVLKKATIRKEQ---EPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVRDT 362
RH+ + RK + P + T G ++RE S P+ +
Sbjct: 412 RHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESP----------SPAPKPRKVE 461
Query: 363 VLEPYADPYYDYEI-ERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERER 421
+ E D + + QY Q + + E ER + + E R R
Sbjct: 462 LSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRR 521
Query: 422 ERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKG 481
R R+R++E + R+RR R +R + R
Sbjct: 522 RHSPSRSASPSPRKRQKE-TSPRGRRRRSPSPPPTRRRRSPS-----PAPPPRRRRTPTP 575
Query: 482 KPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRR 541
P+ R+P PP R+ P + + P +R P RR+ SP SPS +R
Sbjct: 576 PPRRRTPSPPPRRRSPSPRRYSP--PIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKR 633
Query: 542 RKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRS 601
R S S RSS + S S SS+ R SS SRS+R +RS
Sbjct: 634 R----VSHSPPPKQRSSPVTKRRSPSLSSKHRKGSS-----PSRSTR---------EARS 675
Query: 602 FSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTK 661
+ SP+P P P + +PPP + G S + P+P +T P+ ++
Sbjct: 676 PQPNKRHSPSPRPRAPQTSS----SPPPVRRGASSSPQRRQSPSP-----STRPIRRVSR 726
Query: 662 PGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSS 721
+P++ ++ P+ RR + S S SGS +++ S V S S +T+ S
Sbjct: 727 TPEPKKIKKAASPSPQSVRRVSSSRSVSGSPE----PAAKKPPAPPSPVQSQSPSTNWSP 782
Query: 722 SAHSVDSEDMYADLASPVSSASSRSPAPAQTRK--EKGKSKKEDGVKEEKRKRDSSTQPP 779
A PV A S +P+P+ R ++G KK+ K++K K+D +
Sbjct: 783 --------------AVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKH 828
Query: 780 KSAK 783
K K
Sbjct: 829 KKHK 832
Score = 88.2 bits (217), Expect = 3e-17
Identities = 130/546 (23%), Positives = 183/546 (33%), Gaps = 151/546 (27%)
Query: 394 ETEPYHNYRERERERERE---NRQRERERERERDRERERRQREREREREHERDKERQRRK 450
+T P R + R R R + R R R R R R R+R R R R + RR
Sbjct: 273 KTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRM 332
Query: 451 EEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSP--QPPSRQAEPPKKEA------ 502
R R R R+ R + RSP +PP R + PP+K
Sbjct: 333 PPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSA 392
Query: 503 ------------ATTGPQVKRADEWKDPWRRSKSPKKKLGVSV----------------- 533
AT P+ + + P + +++ K ++ VS
Sbjct: 393 SPPRRRHRPSPPATPPPKTRHSPT---PQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRE 449
Query: 534 SPSRARRRRKTSASSASASNSS---------------RSSSRSSSYSGSGSS-------- 570
SPS A + RK S + R + +SSS SGS SS
Sbjct: 450 SPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKR 509
Query: 571 ---------RSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSP-----SPSPTPSPHR 616
R R S S S+ S R S R RS S P SPSP P P R
Sbjct: 510 SHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRR 569
Query: 617 PSIRT----KGEPAPPPGKAGEKSVKKPAPP------PAPPQATKTTAPVPEPTK---PG 663
T + P+PPP + S ++ +PP P+PP +T +P P P + P
Sbjct: 570 RRTPTPPPRRRTPSPPPRRRSP-SPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPS 628
Query: 664 DPREAR---------------------------------RKERPARTP---------PRR 681
P + R R R AR+P PR
Sbjct: 629 PPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRP 688
Query: 682 RTLSGSGSGS----GSSYSGSSSRSRSLSVSSVSSVS----------SATSSSSSAHSVD 727
R S S G+S S +S S S + VS +A+ S S V
Sbjct: 689 RAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVS 748
Query: 728 SEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAG 787
S + P + P+P Q++ VK+ K S + PP+++ G
Sbjct: 749 SSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPS-PPRNSDQEGG 807
Query: 788 GKSSQQ 793
GK ++
Sbjct: 808 GKKKKK 813
Score = 68.2 bits (165), Expect = 4e-11
Identities = 92/394 (23%), Positives = 137/394 (34%), Gaps = 95/394 (24%)
Query: 542 RKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRS-RSR 600
+K + SSR R +SRS S SS R S SRS R R
Sbjct: 145 KKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHR 204
Query: 601 SFSSSPSPSP-----TPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAP 655
+ S SPSP+P TP PS++ K EP+ + +K P P P
Sbjct: 205 TKSRSPSPAPEKKEKTPELPEPSVKVK-EPSVQEATSTSDILKVPKPEP----------- 252
Query: 656 VPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSS 715
+PEP +P + +++++ +T PR R S S S SR+RS S S
Sbjct: 253 IPEPKEPSPEKNSKKEKEKEKTRPRSR-----------SRSKSRSRTRSRSPSHTRPRRR 301
Query: 716 ATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSS 775
S S S + + R P P + R+ + ++ R+R S+
Sbjct: 302 HRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRR--------RRRSSA 353
Query: 776 TQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEP 835
+ G SS S+ ++PP +P +
Sbjct: 354 S---------LSGSSSSSSSSRSRSPPKKPPK---------------------------- 376
Query: 836 SDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQ 895
R S PP K SP S P R+R + S P + +PQ
Sbjct: 377 ----RTSSPPRKTRRLSP--------------SASPPRRRHRPSPPATPPPKTRHSPTPQ 418
Query: 896 SKSSSKVTSVPGKASDPGAASTKSGKASTLSRRE 929
+ ++ + V + PG S K K +RE
Sbjct: 419 QSNRTRKSRV---SVSPGRTSGKVTKHKGTEKRE 449
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 116 bits (290), Expect = 1e-25
Identities = 125/445 (28%), Positives = 188/445 (42%), Gaps = 53/445 (11%)
Query: 294 EPPTESAWERGL------RHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEV 347
E TE ERG + +E + A +E++ D E +R T + ERE +K +
Sbjct: 128 ERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQE 187
Query: 348 FRDWNSRIPRDVRDTVLEPYADPYYDYEIERFW-------RGGQYENFRVQYTETEPYHN 400
R+ + R+ + + +++ + E ER R E R + TE E
Sbjct: 188 RRERERQ--REKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTERER-EK 244
Query: 401 YREREREREREN-RQRERERERERDRERERRQRER------------EREREHERDKERQ 447
ERER ERE R +ERERER+RDR+R+RRQ+ER ER+RE ER +ERQ
Sbjct: 245 QAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQ 304
Query: 448 RRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGP 507
R +E ERER ++ E++R+ R+R+RE++RE E+ + K R + RQ E ++ TG
Sbjct: 305 RERER-ERERNRKRERERE-RERERERQRETERDREKERE-RKRKRQTEMDRERNRQTGR 361
Query: 508 QVKRADE---WKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSY 564
+ +R E ++ R +S +++ R R++ + + + +
Sbjct: 362 EGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRERE 421
Query: 565 SGSGSSRSRSRSSSYSSYSSRS---SRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRT 621
S R R R R R + R R R S+ +P P R +
Sbjct: 422 KDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR---STLYVNPPPRTARSGVVQ 478
Query: 622 KGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRR 681
P G + S P P+A T P P K R A R+ R PR
Sbjct: 479 SDPNRPTRGIRWKSS-------PEDPKAASTRFPWGRPAKASRGRVAGRR----RWEPRL 527
Query: 682 RTLSGSGSGSGSSYSGSSSRSRSLS 706
G G G G SG LS
Sbjct: 528 GEKRGQG-GEGRRPSGGFGTENPLS 551
Score = 94.4 bits (233), Expect = 5e-19
Identities = 112/523 (21%), Positives = 193/523 (36%), Gaps = 61/523 (11%)
Query: 401 YRERERERERE-NRQRERERERERDRERER-RQREREREREHERDKERQ-------RRKE 451
+RER+R+RE+E RQ +RER+R+R++ER R ++RERE ERE ER ++RQ R+
Sbjct: 94 HRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQR 153
Query: 452 EWERERAKRDEKDRQHR-DRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVK 510
+ E+ER ++ +++RQ + +R+R+KERE+EK + + R + + + + G + +
Sbjct: 154 DAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERE 213
Query: 511 RADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSS 570
R E + R + ++ R+RKT + R+S R +
Sbjct: 214 RERETETETERKRQTDRE---------RDRQRKTEREREKQAERERASERETE-----RD 259
Query: 571 RSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPG 630
+ R R R + R R R R R +
Sbjct: 260 KERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERER-------- 311
Query: 631 KAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSG 690
E++ K+ + + + K RE +RK + R R G
Sbjct: 312 ---ERNRKRERERERERERERQRETERDREK---ERERKRKRQTEMDRERNRQTGREGRR 365
Query: 691 SGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPA 750
R R S + E +
Sbjct: 366 QAER---ERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREK 422
Query: 751 QTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTF 810
E+G+ + + K++ R+RD Q + A G+ ++ + PP + G
Sbjct: 423 DRESERGRERGREREKQKGRERDRERQTDRQA-----GRQRKRSTLYVNPPPRTARSGVV 477
Query: 811 VAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPK 870
+ +G R + P D S + P P + SR R +G R P+
Sbjct: 478 QSDP--------NRPTRGIRWKSSPEDPKAAS---TRFPWGRPAKASRGRVAGRRRWEPR 526
Query: 871 PERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGKASDPG 913
+RGQ + P+ +P S++ S PG PG
Sbjct: 527 LGEKRGQGGEG-RRPSGGFGTENPLSQAPS---VFPGPRYTPG 565
Score = 85.9 bits (211), Expect = 2e-16
Identities = 78/248 (31%), Positives = 120/248 (48%), Gaps = 11/248 (4%)
Query: 318 RKEQEPDFEEKRFTV--TIGEDEREFDKENEVFRDWNSRIPRDVRDTVLEPYADPYYDYE 375
R+++ EKR T T + ER +K+ RD + RD R+ E D D +
Sbjct: 58 RQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRD-REKERERQTDRERDRQ 116
Query: 376 IERFWRGGQYENFRVQYTETEPYHNYR-ERERERERENRQRERERERERDRERERRQRER 434
E+ R Q E R E E + + + +RERER+ R E+ERER+ DRER+ RQ ER
Sbjct: 117 REKE-RNRQKERERETEREGERGRDRQTDGQRERERQ-RDAEKERERQTDRERQ-RQTER 173
Query: 435 EREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQ 494
R++E ER+K RQ R+E ER+R K ++ + +H +R RE+ERE+E R Q R+
Sbjct: 174 NRQKEREREKNRQERRER-ERQREKENKTEDRHSERGRERERERETETETERKRQ-TDRE 231
Query: 495 AEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRAR--RRRKTSASSASAS 552
+ +K Q +R + R K +++ R + R R+T +
Sbjct: 232 RDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRT 291
Query: 553 NSSRSSSR 560
R + R
Sbjct: 292 ERDRETER 299
Score = 73.6 bits (179), Expect = 8e-13
Identities = 101/536 (18%), Positives = 180/536 (33%), Gaps = 81/536 (15%)
Query: 404 RERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEK 463
R R +E+ +R + +D + + RER R++E ER +E+++ + E +R+R +R EK
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGD--DRERNRQKERERRREKRQTERETDRKRERRREK 85
Query: 464 DR-----QHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDP 518
DR +HR+R R++E+E+E+ + R Q + ++E T + D D
Sbjct: 86 DRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDG 145
Query: 519 WRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSS 578
R + + + R R+T + +R R R R
Sbjct: 146 QRERERQR--------DAEKERERQTDRERQRQTERNRQKERERE---KNRQERRERERQ 194
Query: 579 YSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVK 638
+ RHS R R R + R R K + K
Sbjct: 195 REKENKTEDRHSERGRERERERETETETERKRQTDRERDRQR----------KTEREREK 244
Query: 639 KPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGS 698
+ A + T+ R+ R+KER +T +R+ + +
Sbjct: 245 QAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQ 304
Query: 699 SSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGK 758
R R + + +E+ +
Sbjct: 305 RERERERE---------------------------------RNRKRERERERERERERQR 331
Query: 759 SKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKL 818
+ D KE +RKR T+ + G + +Q ++ + +Q +E +
Sbjct: 332 ETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSA----REREE 387
Query: 819 TLLNKAADK-GSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQ 877
++ D+ R+R D+D Q +R R R+ G K + +
Sbjct: 388 RERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRE 447
Query: 878 NSKAPAAPADRKRQL-----SPQSKSSSKVTSVPGKAS----------DPGAASTK 918
A RKR P++ S V S P + + DP AAST+
Sbjct: 448 RQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTR 503
Score = 37.7 bits (86), Expect = 0.051
Identities = 33/168 (19%), Positives = 64/168 (38%), Gaps = 9/168 (5%)
Query: 31 DSGSDQDLDGAGVRA----SDLEDEESAARGPSQEEEDNHSDEEDRASEPKSQDQDSEVN 86
+ G D+ DG R ++ E E R ++ E N E +R + + + ++ E
Sbjct: 136 ERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERER-EKNRQERRERERQ 194
Query: 87 ELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVTRELDEHELDYDEEVPEEPAPAVQEDE 146
T E G E E +R ++ E T + E D + E + +
Sbjct: 195 REKENKTEDRHSERGRERERERETETETERKRQT----DRERDRQRKTEREREKQAERER 250
Query: 147 AEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESLEAAKEKKKEDDDGE 194
A + E D+E+ R+ + Q E+++ + + + D + E
Sbjct: 251 ASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETE 298
Score = 35.8 bits (81), Expect = 0.20
Identities = 35/179 (19%), Positives = 67/179 (37%), Gaps = 1/179 (0%)
Query: 44 RASDLEDEESAARGPSQEEEDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDE 103
R + E + R +E+E N E +R +E + + + R E+ E
Sbjct: 101 REKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERE 160
Query: 104 GEEDRTSDLRDEAS-SVTRELDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGT 162
+ DR + E + RE +++ + E + ED + G E + E+ T
Sbjct: 161 RQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETET 220
Query: 163 PREEGKAGVQSVGEKESLEAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPR 221
E + + + E +EK+ E + + E D + E + DR+ + R
Sbjct: 221 ETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKER 279
Score = 35.0 bits (79), Expect = 0.33
Identities = 50/245 (20%), Positives = 91/245 (37%), Gaps = 20/245 (8%)
Query: 5 ESPERDPHSP---EDEEQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQE 61
E+ D HS E E + + ++ + R + ++D R + + E A E
Sbjct: 198 ENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETE 257
Query: 62 EEDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVTR 121
+ E DR + + ++ E + + + E + E + R+ + R
Sbjct: 258 RDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKR 317
Query: 122 ELD-EHELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPRE-----------EGKA 169
E + E E + + + E + + K E D E+ T RE E +
Sbjct: 318 ERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERER 377
Query: 170 GVQSVGEKESLE----AAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRPTCR 225
QS E+E E ++K++E + DG+ + + E E KD + R R R
Sbjct: 378 DRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRERE-KDRESERGRERGRER 436
Query: 226 FFMKG 230
KG
Sbjct: 437 EKQKG 441
Score = 32.7 bits (73), Expect = 1.7
Identities = 31/186 (16%), Positives = 71/186 (38%), Gaps = 7/186 (3%)
Query: 751 QTRKEKGKSKKEDGVKE------EKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQ 804
+ R+EK + +K D +E ++R+R + + + + + ++ T ++ G+
Sbjct: 80 ERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGR 139
Query: 805 PQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGG 864
+Q +E + + + R+R ++++RQ ++ R R+
Sbjct: 140 DRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKEN 199
Query: 865 RLGSPKPERQR-GQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGKASDPGAASTKSGKAS 923
+ ER R + + +RKRQ + K K ++ AS + +
Sbjct: 200 KTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERD 259
Query: 924 TLSRRE 929
RE
Sbjct: 260 KERERE 265
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 115 bits (288), Expect = 2e-25
Identities = 90/270 (33%), Positives = 132/270 (48%), Gaps = 28/270 (10%)
Query: 337 DEREFDKENEVFRDWNSRIPRDVRDTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETE 396
D R+ +++ R R RD R+ P + + + R + E RV +
Sbjct: 612 DNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDR 671
Query: 397 PYHNYRERERERERENRQRERERERERDRERER-------RQREREREREHERDKERQR- 448
RER+RERER+ R+RERERERERDRERE+ R RERERERE ERD+ER R
Sbjct: 672 RDERARERDRERERD-RERERERERERDREREKERELERERAREREREREKERDRERDRD 730
Query: 449 ------RKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRS-----PQPPSRQAEP 497
R+ E ER+R K E++R+ R+R+RE+ERE+E+ + + R + RQ +
Sbjct: 731 RDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDW 790
Query: 498 PKKEAATTGPQVKRADEWKD-------PWRRSKSPKKKLGVSVSPSRARRRRKTSASSAS 550
K+ + KR + +D R+SK + G S SP ++ +RR+ + +
Sbjct: 791 EDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEG-SPSPRQSPKRRREHSPDSD 849
Query: 551 ASNSSRSSSRSSSYSGSGSSRSRSRSSSYS 580
A NS + SRS S S
Sbjct: 850 AYNSGDDKNEKHRLLSQVVRPQESRSLSPS 879
Score = 107 bits (268), Expect = 4e-23
Identities = 154/657 (23%), Positives = 250/657 (38%), Gaps = 139/657 (21%)
Query: 302 ERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVRD 361
ER +E ++ +E+E + E +R E E+E D+E + RD
Sbjct: 684 ERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRD----------- 732
Query: 362 TVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERER 421
+D E ER RER+RE+ERE + ERERER
Sbjct: 733 ----------HDRERER----------------------ERERDREKEREREREERERER 760
Query: 422 ERDRERERRQREREREREHERDKERQRRKEEWE------------RERAKRDEKDRQHRD 469
ER+RERE R+RERERER ERDKER+R++ +WE RE + D R D
Sbjct: 761 ERERERE-RERERERERARERDKERERQR-DWEDKDKGRDDRREKREEIREDRNPRDGHD 818
Query: 470 RDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTG---------------PQVKRA-- 512
+ K+R + +G P PR P R+ P +A +G PQ R+
Sbjct: 819 ERKSKKRYRNEGSPSPRQ-SPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLS 877
Query: 513 -----DEWKDPWR-RSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSG 566
++ + W+ + P++K + + + +S SSR +
Sbjct: 878 PSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDI 937
Query: 567 SGSSRSRSRSSSYSSYSS------------RSSRHSSFSGSRSRSRSFSSSPSP-SPTPS 613
G +S R +S ++ + + R + S SP
Sbjct: 938 IGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKG 997
Query: 614 PHRPSI-----RTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREA 668
+ SI ++KG+ +A ++S KK P PP TK K G ++
Sbjct: 998 QKKKSIEKKRKKSKGDSDISDEEAAQQS-KKKRGPRTPPITTKEELVEMCNGKNGILEDS 1056
Query: 669 RRKER-----------PARTPPRRRTLSGSGSGSGSSYSGSSS------------RSRSL 705
++KE P RT + + + GS+ S SS +
Sbjct: 1057 QKKEDTAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATATATTVP 1116
Query: 706 SVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKK---E 762
+ + ++ ++ATS S+SA ++ + + + + +TR EK ++ E
Sbjct: 1117 ATLAATTAAAATSFSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIE 1176
Query: 763 DGV--KEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTL 820
D K +KR SS +S + G+ + PS G Q G K L
Sbjct: 1177 DAQHRKPMDQKRSSSLGSNRSNRSHTSGR-LRSPSNDSAHRSGDDQSGR-------KRVL 1228
Query: 821 LNKAADKGSRKRYEPSDKDRQSPPPAKR--PNTSPDRGSRDRKS-GGRLGSPKPERQ 874
+ + D+ K E + + + KR P+ S +D +S R SP+ +RQ
Sbjct: 1229 HSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQ 1285
Score = 84.0 bits (206), Expect = 6e-16
Identities = 104/435 (23%), Positives = 168/435 (38%), Gaps = 74/435 (17%)
Query: 389 RVQYTETEPYHNYRERERERERENRQRERERER-----------------ERDRERERR- 430
R +Y E + R+ ER R R RER ERD RE R
Sbjct: 605 RDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERR 664
Query: 431 ---------QREREREREHERDKERQRRKE-EWERERAKRDEKDRQHRDRDREKEREKEK 480
+R RER+RE ERD+ER+R +E E +RER K E +R+ R R+RE+EREKE+
Sbjct: 665 VDRVDDRRDERARERDRERERDRERERERERERDREREKERELERE-RAREREREREKER 723
Query: 481 GKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARR 540
+ + R + ++E + K + ++ R + +++ R
Sbjct: 724 DRERDRD------RDHDRERERERERDREKEREREREERERERERERE-----------R 766
Query: 541 RRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSR 600
R+ A + R + R R R+ R R +
Sbjct: 767 ERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDG--HDERKSKK 824
Query: 601 SFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKP--APPPAPPQATKTTAPVPE 658
+ + SPSP SP R R + P +G+ +K PQ +++ +
Sbjct: 825 RYRNEGSPSPRQSPKR---RREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLS---- 877
Query: 659 PTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATS 718
P+ + R+ R KE R P R+ S Y + + VSSV T
Sbjct: 878 PSHLTEDRQGRWKEED-RKPERKE--------SSRRYEEQELKEK---VSSVDKQREQTE 925
Query: 719 SSSSAHSVDSEDMYADLASPVSSASSR----SPAPAQTRKEKGKSKKEDGVKEEKRKRDS 774
S+ + ++D+ S S R + A+ +K+ K KKED V E+ ++
Sbjct: 926 ILESSR-MRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIET 984
Query: 775 STQPPKSAKPPAGGK 789
+++ + P G K
Sbjct: 985 TSEDGQVFSPKKGQK 999
Score = 71.6 bits (174), Expect = 3e-12
Identities = 171/868 (19%), Positives = 285/868 (32%), Gaps = 99/868 (11%)
Query: 77 KSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVTRELDEHELDYDEEVPE 136
K QD D+E + + +SSP +E G D++ T E +E ++++ +
Sbjct: 92 KRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKER-TPESEEENVEWETNRDD 150
Query: 137 EPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESLEAAKEKKKEDDDGEID 196
+ D + E +K + RE K +++ ++E + KE E +
Sbjct: 151 SDNGDINYDYVHELSLEMKRQKIQ---RELMKLEQENMEKREEIIIKKEVSPE-----VV 202
Query: 197 DGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKGNCTWGMNCRFIHPGVNDKGNYSLITK 256
++ K P RK P+ + K T ++ + N K N S K
Sbjct: 203 RSKLSPSPSLRKSSKSPK-RKSSPKSSSAS-KKDRKTSAVSSPLLDQQRNSKTNQS--KK 258
Query: 257 ADPFPPNGAPPLGPHPLMPANPWGGP--VVDEILPPPPPEPPTESAWERGLRHAKEVLKK 314
P P+ PP+ P + + V D I E T +RG ++ K+
Sbjct: 259 KGPRTPSPPPPI-PEDIALGKKYKEKYKVKDRI------EEKTRDGKDRGRDFERQREKR 311
Query: 315 ----ATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVRDTVLEP---- 366
+T Q R + + + + R R P L P
Sbjct: 312 DKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPR--RKRTPSPSYQRTLTPPLRR 369
Query: 367 YADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRE 426
A PY + + Q ++ P H RE+ R R + R RE
Sbjct: 370 SASPYPSHSLSS-----------PQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERRE 418
Query: 427 RERRQRERERE----REHERDKERQRRKEEWERERAKRDEKD-RQHRDRDREKEREKEKG 481
R +R+RE++ RE+E+D+ R + R RD +D R RDR ++ +
Sbjct: 419 DTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRD 478
Query: 482 KPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRR 541
+ R ++++ P+ +T + A +++D R K+ S S R
Sbjct: 479 SREMRDYSRDTKESRDPRDSRST-----RDAHDYRDREGRDTHRKEDTYPEESRSYGRNH 533
Query: 542 RKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRS 601
+ +S N SR+ SR S RSR R SR SR S S S
Sbjct: 534 LREESSRTEIRNESRNESR-SEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNY 592
Query: 602 FSSSPSPSPTPSPHRPSIRTKGEPAPPPG---KAGEKSVKKPAPPPAPPQATKTTAPVPE 658
S + S P R R + A + GE+ + P + +
Sbjct: 593 HDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRND 652
Query: 659 PTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATS 718
+ + RE RR +R R R R + +
Sbjct: 653 ELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERA 712
Query: 719 SSSSAHSVDSEDMYAD--------------LASPVSSASSRSPAPAQTRKEKGKSKKEDG 764
D D R + +E+ + ++ +
Sbjct: 713 REREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERER 772
Query: 765 VKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKA 824
+E R+RD + + + G+ ++ + P+ G H E K
Sbjct: 773 ERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDG----HDERK------- 821
Query: 825 ADKGSRKRY--EPSDKDRQSPPPAKRPNTSPD----RGSRDRKSGGRLGSPKPERQRGQN 878
S+KRY E S RQS P +R SPD D+ RL S Q ++
Sbjct: 822 ----SKKRYRNEGSPSPRQS--PKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRS 875
Query: 879 SKAPAAPADR-----KRQLSPQSKSSSK 901
DR + P+ K SS+
Sbjct: 876 LSPSHLTEDRQGRWKEEDRKPERKESSR 903
Score = 68.9 bits (167), Expect = 2e-11
Identities = 148/681 (21%), Positives = 227/681 (33%), Gaps = 98/681 (14%)
Query: 224 CRFFMK-GNCTWGMNCRFIH-PGVNDKGNYSLITKADPFPPNGAPPLGPHPLMPANPWGG 281
CR ++K GNC +G CRF+H P KG YS + P P G M
Sbjct: 42 CRNWLKTGNCLYGNTCRFVHGPSPRGKG-YSSNYRRSPERPTG----DLRERMKNKRQDV 96
Query: 282 PVVDEILPPPPPEPPTESAWERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREF 341
+ P RG KE +K I KE+ P+ EE+
Sbjct: 97 DTEPQKRNTEESSSPVRKESSRGRHREKEDIK---ITKERTPESEEENV----------- 142
Query: 342 DKENEVFRDWNSRIPRDVRDTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNY 401
+W + RD D D YDY V E
Sbjct: 143 --------EWETN--RDDSDN-----GDINYDY---------------VHELSLEMKRQK 172
Query: 402 RERE-RERERENRQRERERERERDRERE-RRQREREREREHERDKERQRRKEEWERERAK 459
+RE + E+EN ++ E +++ E R + + K +R+ +K
Sbjct: 173 IQRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASK 232
Query: 460 RDEKDRQ------HRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRAD 513
+D K + R+ + + K+KG PR+P PP PP E G + K
Sbjct: 233 KDRKTSAVSSPLLDQQRNSKTNQSKKKG---PRTPSPP-----PPIPEDIALGKKYKEKY 284
Query: 514 EWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSR 573
+ KD K G R +R + S S A +S SS SS S SGSS R
Sbjct: 285 KVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQR 344
Query: 574 SRSSSYSSYSSRSSRHSSFSGSRSRSRS-----FSSSPSPSPTPSPHRPSIRTKG-EPAP 627
S + S + + RS S SSP +P HR +R KG
Sbjct: 345 HSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHE 404
Query: 628 PPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGS 687
++ ++ ++ K + E + R +R R RR
Sbjct: 405 RTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRR----- 459
Query: 688 GSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSP 747
+R R S S S + +S D P S S+R
Sbjct: 460 --------DARDTRDRRELRDSRDMRDSREMRDYSRDTKESRD-------PRDSRSTRDA 504
Query: 748 APAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQ 807
+ R+ + +KED EE R + +S++ +S + + + +
Sbjct: 505 HDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSR 564
Query: 808 GTF--VAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGGR 865
G + K + + ++ S Y S + R S P R P+R +RD+
Sbjct: 565 GRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDR---YPERDNRDQARDSS 621
Query: 866 LGSPKPERQRGQNSKAPAAPA 886
ER R N + P+
Sbjct: 622 FERRHGERDRRDNRERDQRPS 642
Score = 56.2 bits (134), Expect = 1e-07
Identities = 184/1007 (18%), Positives = 318/1007 (31%), Gaps = 149/1007 (14%)
Query: 2 DVAESPERDPHSPEDEEQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQE 61
D+ + ER P S E+ + + DD D+G D++ V LE + + +
Sbjct: 126 DIKITKERTPESEEENVEWETNRDDS---DNG---DINYDYVHELSLEMKRQKIQRELMK 179
Query: 62 EEDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVTR 121
E + ++ + K + ++LS SP + + + ++S AS
Sbjct: 180 LEQENMEKREEIIIKKEVSPEVVRSKLS----PSPSLRKSSKSPKRKSSPKSSSASKK-- 233
Query: 122 ELDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESLE 181
D + +P + D+ + ++KG TP K+ E
Sbjct: 234 ---------DRKTSAVSSPLL--DQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKE 282
Query: 182 AAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKGNCTWGMNCRFI 241
K K K+ + + DG+ D E K R P G ++ R
Sbjct: 283 --KYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPA--------GQHHSPISSRH- 331
Query: 242 HPGVNDKGNYSLITKADPFPPNGAPP-------LGPHPLMPANPWGGPVVDEILPPPPPE 294
H + G S I + P P P L P A+P+ + P
Sbjct: 332 HSSSSQSG--SSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPP 389
Query: 295 PPTESAWERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDW-NS 353
E+G + + R E+ D KR +ERE++++ RD +
Sbjct: 390 RHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDD 449
Query: 354 RIPRDVRD----------TVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRE 403
R PRD RD L D E+ + R + T H+YR+
Sbjct: 450 REPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRD 509
Query: 404 RE-RERER-------ENRQRERERERERDRERERRQREREREREHERD------------ 443
RE R+ R E+R R RE E R R R R+
Sbjct: 510 REGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPE 569
Query: 444 ---------------------------------KERQRRKEEWERERAKRDEKDRQHRDR 470
ER R E R++A+ +R+H +R
Sbjct: 570 LPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGER 629
Query: 471 DREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLG 530
DR RE+++ +P SP + + +++ +V R D+ +D R + +++
Sbjct: 630 DRRDNRERDQ---RPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERD 686
Query: 531 VSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHS 590
R R R + R R R + R
Sbjct: 687 RERERERERERDREREKERELERERAREREREREKERDRERDRDR-----DHDRERERER 741
Query: 591 SFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQAT 650
+ R R + E A K E+
Sbjct: 742 ERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRR 801
Query: 651 KTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSV 710
+ + E P D + R+ ++ R GS S +S
Sbjct: 802 EKREEIREDRNPRDGHDERKSKKRYRN------------------EGSPSPRQSPKRRRE 843
Query: 711 SSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQ-TRKEKGKSKKEDGVKEEK 769
S S +S D + + L+ V SRS +P+ T +G+ K+ED ++ +
Sbjct: 844 HSPDSDAYNSGD----DKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEED--RKPE 897
Query: 770 RKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGS 829
RK S + K Q+ T Q H+ ++A D+
Sbjct: 898 RKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENK 957
Query: 830 RK---RYEPSDKDRQSPPPAKRPN---TSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPA 883
+K + +P K ++ +R N TS D K G + S + +R++ SK +
Sbjct: 958 KKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKK---SKGDS 1014
Query: 884 APADRKRQLSPQSKSSSKVTSVPGKASDPGAASTKSGKASTLSRREE 930
+D + + K + + K + K+G ++E+
Sbjct: 1015 DISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKED 1061
Score = 56.2 bits (134), Expect = 1e-07
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 5/84 (5%)
Query: 399 HNYRERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERA 458
H+ R E +R+ R + RDR +ER + E +RERE ER RQR EW+R+ A
Sbjct: 1273 HSSRRSSPESDRQVHSRSGSFD-SRDRLQERDRYEHDRERERERRDTRQR---EWDRD-A 1327
Query: 459 KRDEKDRQHRDRDREKEREKEKGK 482
+D + RDR RE+ERE+E+ K
Sbjct: 1328 DKDWPRNRDRDRLRERERERERDK 1351
Score = 55.5 bits (132), Expect = 2e-07
Identities = 53/184 (28%), Positives = 87/184 (47%), Gaps = 12/184 (6%)
Query: 395 TEPYHNYRERERERERENRQRERERER-ERDRERERRQREREREREHERDKER---QRRK 450
+ P + + R ++R R +ER+R E DRERER +R+ R+RE +RD ++ + R
Sbjct: 1278 SSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDT-RQREWDRDADKDWPRNRD 1336
Query: 451 EEWERERAKRDEKDRQHRDRDREKER----EKEKGKPKPRSPQPPSRQAEPPKK-EAATT 505
+ RER + E+D++ RD DRE+ER E+ + + R S Q E K+ EA
Sbjct: 1337 RDRLRERERERERDKR-RDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLE 1395
Query: 506 GPQVKRADEW-KDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSY 564
G + + +D K K SV + + + S + + S+ S
Sbjct: 1396 GEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLEAGDDESKLDDAHSLG 1455
Query: 565 SGSG 568
SG+G
Sbjct: 1456 SGAG 1459
Score = 53.1 bits (126), Expect = 1e-06
Identities = 127/595 (21%), Positives = 213/595 (35%), Gaps = 94/595 (15%)
Query: 9 RDPHSPEDEEQPQGL---SDDDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQEEEDN 65
R+ SP + P+ S D +SG D++ + + + + +ES + PS ED
Sbjct: 827 RNEGSPSPRQSPKRRREHSPDSDAYNSGDDKN-EKHRLLSQVVRPQESRSLSPSHLTEDR 885
Query: 66 HS--DEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEED---RTSDLRDEASSVT 120
EEDR E K + E EL +S + E E E R D+ S
Sbjct: 886 QGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSED 945
Query: 121 RELDEHELDYDEE---VPEEPAPAVQEDEA--EKAGAEDDEEKGEGTPREEGKAGVQSVG 175
RE + D +++ + ++P +ED+ E+ E E G+ ++G+
Sbjct: 946 RETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQ------- 998
Query: 176 EKESLEAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKGNCTWG 235
+K+S+E ++K K D D I D++ + K R P T + + C G
Sbjct: 999 KKKSIEKKRKKSKGDSD-------ISDEEAAQQSKKKRGPRT--PPITTKEELVEMCN-G 1048
Query: 236 MNCRFIHPGVNDKGNYSLITKADPFPPNGAPPLGPHPLMPANPWGGPVVDEILPPPPPEP 295
N + +S + D P H P P L PPPP
Sbjct: 1049 KNGILEDSQKKEDTAFSDWSDED-VPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPV 1107
Query: 296 PTESAWERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRI 355
T +A A AT +TI + N F + +S
Sbjct: 1108 ATATATTVPATLAATTAAAATSFSTS---------AITISTSATPTNTTNNTFANEDSH- 1157
Query: 356 PRDVRDTVLEPYADPYYDYEIERFWR---------------GGQYENFRVQYTETEPYHN 400
R T +E P+ E + + + + R++ + H
Sbjct: 1158 -RKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHR 1216
Query: 401 YRERERERERE----NRQRERERERERDRERERR---------QREREREREHERDKERQ 447
+ + R+R +R RE+ + E ER+ R R +R+ R +
Sbjct: 1217 SGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSR 1276
Query: 448 RRKEEWERERAKR----DEKDR-QHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEA 502
R E +R+ R D +DR Q RDR E +RE+E+ + R + ++A
Sbjct: 1277 RSSPESDRQVHSRSGSFDSRDRLQERDR-YEHDRERERERRDTRQRE--------WDRDA 1327
Query: 503 ATTGPQVKRADEWKDPWRRSKSPKKK---------LGVSVSPSRARRRRKTSASS 548
P+ + D ++ R + K++ + SV R R R +T SS
Sbjct: 1328 DKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESS 1382
Score = 50.4 bits (119), Expect = 8e-06
Identities = 56/186 (30%), Positives = 86/186 (46%), Gaps = 19/186 (10%)
Query: 310 EVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKEN---EVFRDWNSRIPR-DVRDTVLE 365
E+ + R +Q E R T + +D R E R +SR D RD + E
Sbjct: 1242 EITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQE 1301
Query: 366 PYADPY-YDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERD 424
D Y +D E ER R + + + P + R+R RERERE RER++ R+ D
Sbjct: 1302 --RDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERE---RERDKRRDLD 1356
Query: 425 RERERR-----QREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDR---EKER 476
RERER +R+R+R+R+ + + + E + E+D + RD +KER
Sbjct: 1357 RERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKER 1416
Query: 477 -EKEKG 481
+K+ G
Sbjct: 1417 MDKDLG 1422
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 112 bits (281), Expect = 1e-24
Identities = 154/568 (27%), Positives = 210/568 (36%), Gaps = 85/568 (14%)
Query: 402 RERERERERENRQRERERERERDRERERRQ-REREREREHERDKERQRRKEEWERERAKR 460
R R R R R R R R R R R R R R R R R R R + R R++
Sbjct: 601 RRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRS 660
Query: 461 DEKDRQHRDRD-------------------REKEREKEKGKPKPRSPQPPSRQAEPPKKE 501
R+ R R R + R +G+ + RS R +
Sbjct: 661 RTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQR 720
Query: 502 AATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRS 561
+G +R ++ + RRS+S + SR RR S SS + SR S R
Sbjct: 721 RGRSGSSSERKNKSRTSQRRSRSNSSP---EMKKSRISSRRSRSLSSPRSKAKSRLSLRR 777
Query: 562 S------------------SYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFS 603
S S SGS +++SR+ S SS S S + SR S
Sbjct: 778 SLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSS 837
Query: 604 SSPSP---SPTP-------SPH------RPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPP 647
SSP P S TP SP P R+ E +P P + +PP
Sbjct: 838 SSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPP 897
Query: 648 QATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSV 707
+ +T P P++ P+ + A PR+R+ SGS S S S + ++ RS SV
Sbjct: 898 RVKSSTPPRQSPSRSSSPQPKVK----AIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSV 953
Query: 708 SSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAP-----AQTRKEKGKSKKE 762
S S+V S S S D +P + S S +P AQT S +
Sbjct: 954 SPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSK 1013
Query: 763 DGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLN 822
+EK K P S AG KSS PPG+ G V+ ++K
Sbjct: 1014 SPCPQEKSKDSLVQSCPGSLSLCAGVKSS--------TPPGESYFG--VSSLQLKGQSQT 1063
Query: 823 KAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSG--GRLGSPKPERQ-RGQNS 879
+ E +SP + TSP +G R R S L S P RQ RG+ S
Sbjct: 1064 SPDHRSDTSSPEVRQSHSESPSLQSKSQTSP-KGGRSRSSSPVTELASRSPIRQDRGEFS 1122
Query: 880 KAPAAPADRKRQLSP-QSKSSSKVTSVP 906
+P K +SP QS+ S +S P
Sbjct: 1123 ASPML----KSGMSPEQSRFQSDSSSYP 1146
Score = 111 bits (278), Expect = 3e-24
Identities = 143/604 (23%), Positives = 226/604 (37%), Gaps = 80/604 (13%)
Query: 389 RVQYTETEPYHNYRERERERER-----ENRQRERERERERDRERERRQREREREREHERD 443
R TET E++ ER R + + + R RE +Q E + +
Sbjct: 115 RPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLV 174
Query: 444 KERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAA 503
+E + +++ K+ +KDR R RE++K K + ++E K++
Sbjct: 175 RESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRS----ESESKKRKHR 230
Query: 504 TTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRR--RKTSASSASASNSSRSSSRS 561
+ P+ KR +SK K+K S +P+ RR R TSA SAS+S++SRS
Sbjct: 231 SPTPKSKR---------KSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRS---- 277
Query: 562 SSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRT 621
RSRS ++ + + S SG R + S P + T P P T
Sbjct: 278 ---------RSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETAT 328
Query: 622 KGEPAPPPGK---AGEKSVKKPAP----------PPAP-----------PQATKTTAPVP 657
K +P K EKS +P+P PPAP PQ TT
Sbjct: 329 KQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQ 388
Query: 658 EPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVS------ 711
EP P R P ++P + S S S S SR S S S
Sbjct: 389 EPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPG 448
Query: 712 ---SVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEE 768
+SS+ +S + +H D SRSPA A+ + + ++ + G
Sbjct: 449 SHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRG---- 504
Query: 769 KRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKG 828
R S Q +S G+S S ++ PQ+ + + + +++A +G
Sbjct: 505 -HSRSRSPQWRRSRSAQRWGRSR---SPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRG 560
Query: 829 SRKRYEPSDKDR-QSPPPAK----RPNTSPDRGSRDRKSGGRLGSPKPERQRGQN-SKAP 882
P+ + R +S PA+ R T R SR R R + +RG++ S+ P
Sbjct: 561 RSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTP 620
Query: 883 AAPADRKRQLSPQSKSSSKVTSVPGKASDPGAASTKSGKASTLSRREELLKQLKAVEDAI 942
A R R + S G++ A ++ T +RR + A
Sbjct: 621 ARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGR 680
Query: 943 ARKR 946
+R R
Sbjct: 681 SRSR 684
Score = 100 bits (250), Expect = 5e-21
Identities = 133/576 (23%), Positives = 211/576 (36%), Gaps = 67/576 (11%)
Query: 399 HNYRERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERA 458
H+ R R R R R R R R RR R R R R + RR R A
Sbjct: 563 HSRSPATRGRSRSRTPARRGRSRSRTPAR-RRSRSRTPTRRRSRSRTPARRGRSRSRTPA 621
Query: 459 KRDEKDRQH-RDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKD 517
+R + R R R R + + G+ + R+P +R+ + A G R +
Sbjct: 622 RRRSRTRSPVRRRSRSRSPARRSGRSRSRTP---ARRGRSRSRTPARRGRSRSRTPARRS 678
Query: 518 PWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSG-SGSSRSRSRS 576
RS++P ++ SR+R R+ + S S RS SR+ G SGSS R
Sbjct: 679 GRSRSRTPARR-----GRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNK 733
Query: 577 SSYSSYSSRSSRHSSFSGSR---SRSRSFSSSPSPSPTPSPHRPSIRTKGEPAP------ 627
S S SRS+ SR RSRS SS S + + R S+ + P P
Sbjct: 734 SRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSL-SGSSPCPKQKSQT 792
Query: 628 PPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDP-REARRKERP-----ARTPPRR 681
PP ++ S + A PP+ +++++ P K P R++ P + TPPR+
Sbjct: 793 PPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQ 852
Query: 682 RTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSS 741
+++ S + S + R S + S T S S + + S
Sbjct: 853 GSIT---SPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSP 909
Query: 742 ASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPA--------------- 786
+ S SP P + + G R +S P+ ++ +
Sbjct: 910 SRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSH 969
Query: 787 GGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPA 846
G SS + PP Q G+ + ++K ++ PS +SP P
Sbjct: 970 SGSSSPDTKVKPETPPRQSHSGSISPYPKVK-----------AQTPPGPSLSGSKSPCPQ 1018
Query: 847 KRPNTSPDR---GSRDRKSGGRLGSPKPE--------RQRGQNSKAPAAPADRKRQLSPQ 895
++ S + GS +G + +P E + +GQ+ +P +D Q
Sbjct: 1019 EKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQ 1078
Query: 896 SKSSSKVTSVPGKASDPGAASTKSGKASTLSRREEL 931
S S S + S G S S + L+ R +
Sbjct: 1079 SHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPI 1114
Score = 93.6 bits (231), Expect = 8e-19
Identities = 128/539 (23%), Positives = 198/539 (36%), Gaps = 68/539 (12%)
Query: 404 RERERERENRQRERER---ERERDRERERRQREREREREHERDKERQRRKEEWERERAKR 460
R R +R R R +R R R+ +R R R R R H R + R R R
Sbjct: 524 RSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGR 583
Query: 461 DEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWR 520
R R R + + + + + + + SR P ++ + T P +R+
Sbjct: 584 SRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRS-------- 635
Query: 521 RSKSPKKKLGVSVSPSRARRRRKTSA---SSASASNSSRSSSRSSSYS-GSGSSRSRS-- 574
RS+SP ++ G R R +T A S S + + R SRS + + SG SRSR+
Sbjct: 636 RSRSPARRSG--------RSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPA 687
Query: 575 ---RSSSYSSYSSRSSRHSSFSGSRSRSRS---FSSSPSPSPTPSPHRPSIRTKGEPAPP 628
RS S + RS S RS SR+ S S S + R S R + P
Sbjct: 688 RRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSP 747
Query: 629 PGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSG 688
K S ++ +P K+ + P ++ ++TPPRR
Sbjct: 748 EMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQK----SQTPPRR------- 796
Query: 689 SGSGSSYSGSSSRS---RSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSR 745
S SGSS + SR+ RS S SS + + S +HS S +P S
Sbjct: 797 SRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSIT 856
Query: 746 SP-APAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQ 804
SP A Q+ + +S E E + R S + PP S+ +P ++ Q
Sbjct: 857 SPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQ 916
Query: 805 PQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGG 864
P+ ++ + + S SP P++ + + R SR
Sbjct: 917 PKVKAIISPR-------------------QRSHSGSSSPSPSRVTSRTTPRRSRSVSPCS 957
Query: 865 RLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPG-KASDPGAASTKSGKA 922
+ S R S +P K + P+ S ++ P KA P S K+
Sbjct: 958 NVESRLLPRYSHSGSSSPDTKV--KPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKS 1014
Score = 91.7 bits (226), Expect = 3e-18
Identities = 130/561 (23%), Positives = 209/561 (37%), Gaps = 64/561 (11%)
Query: 404 RERERERENRQRERERERERDRERERRQRERE----REREHERDKERQRRKEEWERERAK 459
R RER + E + R RR R R+ + ++ +
Sbjct: 1412 RTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPR 1471
Query: 460 RDEKDRQHRDRDREKEREKEKGKPKPRSPQPP--SRQAEPPKKEAATTGPQVKRADEWKD 517
+ R D E + + +P+ RSP P + + P++E + + V + +
Sbjct: 1472 TPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVART 1531
Query: 518 PWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSG---SSRSRS 574
P + + V PS + + R S SS + +R+ R S SGS S+SR
Sbjct: 1532 PLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRL 1591
Query: 575 RSSSYSSYSSRSSRHSSFSGSRSRSRSFSS----SPSPSPTPSPHRPSIRTKGEPAPPPG 630
S SS + + R++S S SS +P+P P R +KG P G
Sbjct: 1592 SPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEG 1651
Query: 631 KAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSG 690
+ +S P PP A + + PEP + +RTPPRRR+ S
Sbjct: 1652 SSSTES--SPEHPPKSRTARRGSRSSPEP------------KTKSRTPPRRRSSRSSPEL 1697
Query: 691 SGSSYSGSSSRSRSLSVSSVSSV------SSATSSSSSAHSVDSEDMYADLASPVSSASS 744
+ + SRS S S + S S + SS A S +SP + +S
Sbjct: 1698 TRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTS 1757
Query: 745 R-----SPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQ 799
R SP P ++ + +S++E +R R S+Q + +S + ++
Sbjct: 1758 RRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQ----RSRSRSRVTRR 1813
Query: 800 APPGQPQQGTFVAHKEIKLTLLNKAADKG-----SRKRYEPSDKDRQSPPPAKRPNTSPD 854
G A +E T + + SRKR + R SP P KR S
Sbjct: 1814 RRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKR----SRSRTSPAPWKR---SRS 1866
Query: 855 RGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQS----KSSSKVTSVPGKAS 910
R S R +P R+R S++ +P R+R S S +S S+ + V + S
Sbjct: 1867 RASPATHRRSRSRTPLISRRR---SRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRS 1923
Query: 911 ---DPGAASTKSGKASTLSRR 928
P +S + +RR
Sbjct: 1924 RSRTPPVTRRRSRSRTPTTRR 1944
Score = 91.3 bits (225), Expect = 4e-18
Identities = 132/545 (24%), Positives = 200/545 (36%), Gaps = 103/545 (18%)
Query: 405 ERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKD 464
E E + R R E + + R R R E R+ R R+ +
Sbjct: 1656 ESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPE 1715
Query: 465 RQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKS 524
+ R R + P SP+P + ++ +A++ P+ K RR +S
Sbjct: 1716 TRSRTPPRHRR------SPSVSSPEPAEKSRSSRRRRSASS-PRTKTTS------RRGRS 1762
Query: 525 PK-KKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYS 583
P K G+ S SR+RR + + S SS+S+SR S S S +R R S Y
Sbjct: 1763 PSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGG-SGYH 1821
Query: 584 SRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPP 643
SRS S + SR R S TP R R++ PAP ++S + +P
Sbjct: 1822 SRSPARQESSRTSSRRRR-----GRSRTPPTSRKRSRSRTSPAP-----WKRSRSRASPA 1871
Query: 644 PAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSR 703
++T P +RR+ R +P RR S S +S + SRSR
Sbjct: 1872 THRRSRSRT------------PLISRRRSRSRTSPVSRRR-----SRSRTSVTRRRSRSR 1914
Query: 704 SLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKED 763
ASPVS SRS P TR+ + +S+
Sbjct: 1915 --------------------------------ASPVSRRRSRSRTPPVTRR-RSRSR--- 1938
Query: 764 GVKEEKRKRDSSTQPP------KSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIK 817
R+R S PP +S PP + S+ ++P + + +
Sbjct: 1939 --TPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRS 1996
Query: 818 LTLLNKAADKGSRKRYEPSDKDR---QSPPPAKRPNTS-----PDRGSRDRKS---GGRL 866
T + + SR R P + R ++PP +R + S P + SR R R
Sbjct: 1997 RT--SPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRS 2054
Query: 867 GSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGKASDPGA----ASTKSGKA 922
S P RG+ S + PA R+R S S S+ + P + G+ + S +
Sbjct: 2055 RSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRM 2114
Query: 923 STLSR 927
S SR
Sbjct: 2115 SCFSR 2119
Score = 89.7 bits (221), Expect = 1e-17
Identities = 110/417 (26%), Positives = 164/417 (39%), Gaps = 107/417 (25%)
Query: 486 RSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTS 545
R+P P SR + P + D+ + P + S + + ++ + A + +S
Sbjct: 2423 RAPSPSSRMGQAPSQSLLPPAQ-----DQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSS 2477
Query: 546 ASSASASNSSRSSSRSSSYSGSG----------SSRSRSRSSSYSSYSSRSSRHSSFSGS 595
+ A+ ++S+ + S G +S + S+ ++ R SS S S
Sbjct: 2478 GAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSS 2537
Query: 596 RSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAP 655
S S S SSS S S + S S ++G P + K V P+P PAP +A + P
Sbjct: 2538 SSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRV--PSPTPAPKEAVREGRP 2595
Query: 656 VPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSS 715
PEPT A+RK RR + S S S S SS S SSS S S S SS SS SS
Sbjct: 2596 -PEPTP------AKRK--------RRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2640
Query: 716 ATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSS 775
++SSSSS SP+PA K +
Sbjct: 2641 SSSSSSS-----------------------SPSPA------------------KPGPQAL 2659
Query: 776 TQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEP 835
+P KPP G + S+ P P ++ D S Y P
Sbjct: 2660 PKPASPKKPPPGERRSRSPRKP-----------------------IDSLRDSRSLS-YSP 2695
Query: 836 SDKDRQSPPPAKR--PNTSPDRGSRDRKSGG--------RLGSPKPERQRGQNSKAP 882
++ R SP P+ R ++S +RGSR + G R +P P R ++S++P
Sbjct: 2696 VERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
Score = 89.0 bits (219), Expect = 2e-17
Identities = 194/936 (20%), Positives = 307/936 (32%), Gaps = 159/936 (16%)
Query: 4 AESPERDPHSPEDEEQPQGLSDDDILRDSG---SDQDLDGAGVRASDLEDEESAARGPSQ 60
A SPE P + LRD S L G+ D+ R PS+
Sbjct: 1422 ASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIP------RTPSR 1475
Query: 61 EEEDNHSDEEDRA--SEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASS 118
+ S E +A P+ + + EL+ + E G E D+ + R
Sbjct: 1476 GRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQ 1535
Query: 119 VTRELDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKE 178
+R ELD +P+ + QE +E + D + K R+ ++G + +
Sbjct: 1536 RSRSGSSQELDV------KPSASPQE-RSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSK 1588
Query: 179 SLEAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKGNCTWGMNC 238
S + + + E+ D + G P + PR R G+ + G
Sbjct: 1589 S-RLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGR-- 1645
Query: 239 RFIHPGVNDKGNYSLITKADPFPPNGAPPLGPHPLMPANPWGGPVVDEILPPPPPEPPTE 298
G + +G+ S + + P + G PEP T+
Sbjct: 1646 -----GPSPEGSSSTESSPEHPPKSRTARRGSRS-------------------SPEPKTK 1681
Query: 299 SAW---ERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRI 355
S R R + E+ +KA + + R E SR
Sbjct: 1682 SRTPPRRRSSRSSPELTRKARLSRRS-----------------RSASSSPET----RSRT 1720
Query: 356 PRDVRDTVLEPYADPYYDYEIERFWRGGQYENFRVQYTE-TEPYHNYRERERERERENRQ 414
P R + +P R R + P R +R R R R+
Sbjct: 1721 PPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRRE 1780
Query: 415 RERE-RERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDRE 473
+ R R R+R + R R+R R R R+R + R E R R R
Sbjct: 1781 KTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRG 1840
Query: 474 KEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSV 533
+ R + + RS P+ PW+RS+S
Sbjct: 1841 RSRTPPTSRKRSRSRTSPA-------------------------PWKRSRS-------RA 1868
Query: 534 SPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFS 593
SP+ RR R S + RS SR+S S RSRSR +S + R SR +
Sbjct: 1869 SPATHRRSR----SRTPLISRRRSRSRTSPVS---RRRSRSR----TSVTRRRSRSRASP 1917
Query: 594 GSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTT 653
SR RSRS + P P+ R + PP + + PP ++ T
Sbjct: 1918 VSRRRSRS-RTPPVTRRRSRSRTPTTRRRSRSRTPP--VTRRRSRSRTPPVTRRRSRSRT 1974
Query: 654 APVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSV 713
+P+ RR+ R +P RR S S +S +R S S S V
Sbjct: 1975 SPI-----------TRRRSRSRTSPVTRR----------RSRSRTSPVTRRRSRSRTSPV 2013
Query: 714 SSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRD 773
+ S S + ++ P + SRSP + R + G KR
Sbjct: 2014 TRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARG------KRS 2067
Query: 774 SSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRY 833
+ PP + A G SS + + A P P + + L + SR
Sbjct: 2068 LTRSPPAIRRRSASGSSSDR---SRSATP--PATRNHSGSRTPPVALNSSRMSCFSRPSM 2122
Query: 834 EPSDKDRQSPPPAKRP--NTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQ 891
P+ DR P P ++ + G + P P Q + P A
Sbjct: 2123 SPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHA----- 2177
Query: 892 LSPQSKSSSKVTSVPGKASDPGAASTKSGKASTLSR 927
QS+ + +T++ + P + + +G A+ +S+
Sbjct: 2178 ---QSRIALALTAISLGTARPPPSMSAAGLAARMSQ 2210
Score = 85.5 bits (210), Expect = 2e-16
Identities = 128/553 (23%), Positives = 204/553 (36%), Gaps = 68/553 (12%)
Query: 414 QRERERERERDRERERRQREREREREHERDKERQRRKEEWERERA----KRDEKDRQHRD 469
QR R + + + E + D + + R +R R+ + D K R
Sbjct: 1535 QRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPR 1594
Query: 470 RDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKL 529
R R + K KP+ +P+ S P+ +A +R+ R SP+
Sbjct: 1595 RSRSGSSPEVKDKPRA-APRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSS 1653
Query: 530 GVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRH 589
SP + R +A SRSS + S + R SRSS + +R SR
Sbjct: 1654 STESSPEHPPKSR-------TARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSR- 1705
Query: 590 SSFSGSRSRSRSFSSSPSP-SPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQ 648
RSRS SSSP S TP HR R+ +P P + S ++ + +
Sbjct: 1706 --------RSRSASSSPETRSRTPPRHR---RSPSVSSPEPAEKSRSSRRRRSASSPRTK 1754
Query: 649 ATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVS 708
T P P G R R R RRR SGS + S SRSR
Sbjct: 1755 TTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSR----- 1809
Query: 709 SVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEE 768
V+ S HS SP SSR+ +R+ +G+S+ ++
Sbjct: 1810 ----VTRRRRGGSGYHS----------RSPARQESSRT----SSRRRRGRSRTPPTSRKR 1851
Query: 769 KRKRDSST--QPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAAD 826
R R S + +S PA + S+ TP + + + V+ + +
Sbjct: 1852 SRSRTSPAPWKRSRSRASPATHRRSRS-RTPLISRRRSRSRTSPVSRRRSRSR--TSVTR 1908
Query: 827 KGSRKRYEPSDKDR---QSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPA 883
+ SR R P + R ++PP +R + S +R R R +P R+R ++ P
Sbjct: 1909 RRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRR---SRSRTPPVTRRRSRSRTPPV 1965
Query: 884 APADRKRQLSP--QSKSSSKVTSVPGKAS----DPGAASTKSGKASTLSRREELLKQLKA 937
+ + SP + +S S+ + V + S P + S ++RR + A
Sbjct: 1966 TRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPA 2025
Query: 938 VEDAIARKRAKIP 950
+ R R++ P
Sbjct: 2026 IR---RRSRSRTP 2035
Score = 84.0 bits (206), Expect = 6e-16
Identities = 143/684 (20%), Positives = 257/684 (37%), Gaps = 147/684 (21%)
Query: 396 EPYHNYRERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWER 455
+PY RE R +Q++++++++R R E RER++ ++ K R E
Sbjct: 169 KPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRS------ES 222
Query: 456 ERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEW 515
E KR K R + + K ++K++ + + +P P SR+A + + R+
Sbjct: 223 ESKKR--KHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRS--- 277
Query: 516 KDPWRRSKSPKKKL------GVSVSPSRARRRRK--------TSASSASASNSSRSSSRS 561
RS+S K G S SP+ RR T+++ +S + + S
Sbjct: 278 -----RSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPS 332
Query: 562 SSYSGSGSSRSRSRSSSYSSYSSRSS--------------RH------------------ 589
S Y + ++ S RSS RH
Sbjct: 333 SPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVN 392
Query: 590 --SSFSGSRSRS------------RSFSSSPSPSPTP-SPHRPSIRTKGEPAPPPGKAGE 634
S S +R RS S SS PSP PT S H S +PAP PG E
Sbjct: 393 PPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHRE 452
Query: 635 KSVKKPAPPPAPPQATKTTAPVPEPTK----PGDPREARRKERPARTPPRR---RTLSGS 687
S + + +A + + P++ P A+R +RTP +R R+ S
Sbjct: 453 ISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQ 512
Query: 688 GSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAH----SVDSEDMYADLASPVSSAS 743
S S+ SRS S S S S + S + + SP +
Sbjct: 513 WRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGR 572
Query: 744 SRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPG 803
SRS PA+ +G+S+ + R R + + +S P G+S + +++
Sbjct: 573 SRSRTPAR----RGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTR 628
Query: 804 QPQQGTFVAHKEIKLTLLNKA---ADKGSRKRYEPSDKDR-QSPPPAKRPNTS------- 852
P + + + + +++ A +G + P+ + R +S PA+R S
Sbjct: 629 SPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPAR 688
Query: 853 --------PDRG--------------SRDRKSGGRLGSPKPERQRGQNS----KAPAAPA 886
P RG SR + GR GS + + + S ++ ++P
Sbjct: 689 RGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPE 748
Query: 887 DRKRQLS---------PQSKSSSKVT---SVPGKASDPGAAS------TKSGKASTLSRR 928
+K ++S P+SK+ S+++ S+ G + P S ++SG + ++
Sbjct: 749 MKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKS 808
Query: 929 EELLKQLKAVEDAIARKRAKIPGK 952
++ ++ ++++K P +
Sbjct: 809 RTPPRRSRSSSSPPPKQKSKTPSR 832
Score = 68.2 bits (165), Expect = 4e-11
Identities = 129/555 (23%), Positives = 190/555 (34%), Gaps = 144/555 (25%)
Query: 402 RERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRD 461
R R +R R + + R +RR R E ++ + RR R+K
Sbjct: 712 RSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSP-EMKKSRISSRRSRSLSSPRSKAK 770
Query: 462 EKDRQHRDRDREKEREKEKGKPKPR-----SPQPPSRQAEPPKKEAATTGPQVKRADEWK 516
+ R K+K + PR S QP ++ PP++ +++ P K+ K
Sbjct: 771 SRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKS--K 828
Query: 517 DPWRRSKS-----PKKKLGV-----SVSPSRAR------RRRKTSASSASASNSSRSSSR 560
P R+S S PK K G S++ +A +RR SS SR+ SR
Sbjct: 829 TPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSR 888
Query: 561 SSSYSGSGSSRSRSRSS-----SYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPH 615
+S SGSS R +SS S S SS + + R RS S SSSPSPS S
Sbjct: 889 ---HSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRT 945
Query: 616 RP--------------------------SIRTKGEPAPPPGKAGEKS------VKKPAPP 643
P S TK +P PP ++ S VK PP
Sbjct: 946 TPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPP 1005
Query: 644 ---------PAPPQATKTT------------APVPEPTKPGDPR---EARRKERPARTPP 679
P P + +K + A V T PG+ + + + ++T P
Sbjct: 1006 GPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSP 1065
Query: 680 RRRT--------LSGSGSGSGSSYSGSSSRS-RSLSVSSVSSVSSAT------------- 717
R+ S S S S S S +S + RS S S V+ ++S +
Sbjct: 1066 DHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASP 1125
Query: 718 --------------SSSSSAHSVDSEDMYAD--------------------LASPVSSAS 743
S SSS +VDS + ASP
Sbjct: 1126 MLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKD 1185
Query: 744 SRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPG 803
SP P Q R E K+ + + + + P + A SSQ +
Sbjct: 1186 KFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKS 1245
Query: 804 QPQQGTFVAHKEIKL 818
+ G ++H +L
Sbjct: 1246 EEPAGQILSHLSSEL 1260
Score = 59.3 bits (142), Expect = 2e-08
Identities = 143/639 (22%), Positives = 213/639 (33%), Gaps = 115/639 (17%)
Query: 393 TETEPYHNYRERERER---ERENRQRERERERERDRER-----ERRQRERE----REREH 440
+ T P R R R R +R R R R R R RR R R R+R
Sbjct: 1984 SRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSR 2043
Query: 441 ERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPP-----SRQA 495
R RR+ R R ++ + + RS PP S
Sbjct: 2044 SRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSR 2103
Query: 496 EPPKKEAATTGPQVKRADEWKDPWRRSKSP--KKKLGVSVSPSRARRRRKTSASSASASN 553
PP ++ R P R +SP + LG S +P ++ S
Sbjct: 2104 TPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPR 2163
Query: 554 SSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSP--- 610
R+S SR ++ S ++R S +G +R S P+P P
Sbjct: 2164 IP-DHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAAR---MSQVPAPVPLMS 2219
Query: 611 ------------TPSPHRPSIRTKGEPAPP-PGKAGEKSVKKPAPPPAPPQATKTTAPVP 657
P+ ++ P P + PA A A+ TA P
Sbjct: 2220 LRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAP 2279
Query: 658 EPTKPGDPREARRKE---RPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVS 714
DPR ARTP LS +GSG+ + + S SR+ + +++
Sbjct: 2280 SAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLV 2339
Query: 715 SATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDS 774
S+ ++A + A +P S S+R APA + G + V +R S
Sbjct: 2340 GPRSAHATAPVNIAGSRTAAALAPASLTSARM-APALS----GANLTSPRVPLSAYERVS 2394
Query: 775 S-TQPP-----KSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKG 828
T PP +S PP+ SQ T ++AP + G
Sbjct: 2395 GRTSPPLLDRARSRTPPSA--PSQSRMTSERAPSPSSRMG-----------------QAP 2435
Query: 829 SRKRYEPSDKDRQSPPPAKRPN--------TSPDRGSRDRKSG-------------GRLG 867
S+ P+ +SP P+ + T+P GS+ SG G L
Sbjct: 2436 SQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLS 2495
Query: 868 SPKPERQRGQNSKAPAA-------------PADRKRQLSPQSKSSSKVTSVPGKASDPGA 914
P P + PA+ PA +R S S SSS +S +S +
Sbjct: 2496 VPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSS----SSSSSS 2551
Query: 915 ASTKSGKASTLSRREELLKQLKAVEDAIARKRAKIPGKA 953
+S+ SG +S+ S L V+ +A KR P A
Sbjct: 2552 SSSSSGSSSSDSEGSSL-----PVQPEVALKRVPSPTPA 2585
Score = 58.5 bits (140), Expect = 3e-08
Identities = 90/415 (21%), Positives = 159/415 (38%), Gaps = 52/415 (12%)
Query: 532 SVSPSR---ARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSR 588
+V+PS A R T+ + A + ++ + S +GSG+ + + S SS + ++
Sbjct: 2276 AVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPS-SSRTPQAPA 2334
Query: 589 HSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKP-------- 640
++ G RS + + + S T + P+ T AP A S + P
Sbjct: 2335 SANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVS 2394
Query: 641 --------------APPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSG 686
PP AP Q+ T+ P P+ ++ PA+ PR S
Sbjct: 2395 GRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSA 2454
Query: 687 SGSGSGSSYSGSS--SRSRSLSVSSVSSVSSATSSSSSAHSVDSEDM-YADLASPVSSAS 743
S + ++ + S+SLS +V++ +S+ + SV + + ++D+ P +S
Sbjct: 2455 FSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTG 2514
Query: 744 SRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPG 803
++ P+ A + K ++ SS+ S+ +G SS + + P
Sbjct: 2515 AQQPS-ALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGS---SLPV 2570
Query: 804 QPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSG 863
QP+ VA K + A K + + P + P PAKR S S S
Sbjct: 2571 QPE----VALKRVPSPT---PAPKEAVREGRPPE-----PTPAKRKRRSSSSSSSSSSSS 2618
Query: 864 GRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGKASDPGAASTK 918
S +S + ++ + S S SSS + PG + P AS K
Sbjct: 2619 SSSSS-------SSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPK 2666
Score = 47.0 bits (110), Expect = 8e-05
Identities = 97/469 (20%), Positives = 168/469 (35%), Gaps = 26/469 (5%)
Query: 481 GKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARR 540
G+ + + + + A PP+++A + P+ K D++ P+ P+ L + R
Sbjct: 1155 GQSRLETAESKEKMALPPQEDATASPPRQK--DKFS-PFPVQDRPESSLVFKDTLRTPPR 1211
Query: 541 RRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSR 600
R + SS + + SS +S + S SS S S
Sbjct: 1212 ERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTS----- 1266
Query: 601 SFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPT 660
+F SSP P+ +++ + + + + P +P + +P+ E +
Sbjct: 1267 NFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENS 1326
Query: 661 KPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSS 720
G P E R P T S + SL + S+ SS SSS
Sbjct: 1327 F-GSPLEFRNSG-PLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSS 1384
Query: 721 S-SAHSVDSEDMYAD--LASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQ 777
S +V+ M ++ ++SPV A R+P+ ++ K+ + R+ S +
Sbjct: 1385 ELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSS 1444
Query: 778 PPKSAKPPAGGKSSQQPSTP-QQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPS 836
P + S S+P + P P +G + L + SR P
Sbjct: 1445 PGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPE 1504
Query: 837 DKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNS-----KAPAAPADRKRQ 891
++ P +R S S D+K+ R +P +R R +S K A+P +R
Sbjct: 1505 LNNKCLTPQRER---SGSESSVDQKTVAR--TPLGQRSRSGSSQELDVKPSASPQERSE- 1558
Query: 892 LSPQSKSSSKVTSVPGKASDPGAASTKSGKASTLSRREELLKQLKAVED 940
S S S T P + +S + S LS R V+D
Sbjct: 1559 -SDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKD 1606
Score = 38.1 bits (87), Expect = 0.039
Identities = 55/180 (30%), Positives = 67/180 (37%), Gaps = 62/180 (34%)
Query: 480 KGKPKPR-SPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRA 538
K P P +P+ R+ PP+ A KR RRS S S S S +
Sbjct: 2577 KRVPSPTPAPKEAVREGRPPEPTPA------KRK-------RRSSSSSSSSSSSSSSSSS 2623
Query: 539 RRRRKTSASSASASNSSRSSSRSSSYSGS------------------GSSRSRS------ 574
+S+SS+S+S+SS SSS SSS S + G RSRS
Sbjct: 2624 SSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPID 2683
Query: 575 -----RSSSYSSYSSR--------------SSRHSSFSGSRSRSRSFS-----SSPSPSP 610
RS SYS R SS S G R SRS S +PSP P
Sbjct: 2684 SLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRP 2743
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 103 bits (257), Expect = 8e-22
Identities = 135/578 (23%), Positives = 233/578 (40%), Gaps = 78/578 (13%)
Query: 395 TEPYHNYRERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWE 454
TE E+E + E + E E E E + E E++ + ++E
Sbjct: 467 TEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKS 526
Query: 455 RERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADE 514
AK EK+ + + K EK K K + PP +A+ P+KE A + +VK ++
Sbjct: 527 PAEAKSPEKE-EAKSPAEVKSPEKAKSPAKEEAKSPP--EAKSPEKEEAKSPAEVKSPEK 583
Query: 515 WKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASS-ASASNSSRSSSRS-SSYSGSGSSRS 572
K P +K K + SP +A+ K A S A A + + ++S + ++S
Sbjct: 584 AKSP---AKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKS 640
Query: 573 RSRSSSYSSYSSRS-SRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGK 631
++ + S ++S + + S +++S + + SP SP + ++ E A P K
Sbjct: 641 PTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSP-EKAKSPVK 699
Query: 632 AGEKSVKKPAPP-----PAPPQA---TKTTAPVPEPTKPGDPREARRKERPARTPPRRRT 683
KS +K P +P +A K A PE K EA+ E+ A++P + +T
Sbjct: 700 EEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEK-AKSPEKAKT 758
Query: 684 LS-GSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYA--------- 733
L S + + S + + S V S A S ED A
Sbjct: 759 LDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKE 818
Query: 734 DLASPV----------------SSASSRSPAPAQTRKEKGKSKKEDGVKEE------KRK 771
++ SPV + ++PA +T +EK SKKE+ K+E + K
Sbjct: 819 EVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKT-EEKKDSKKEEAPKKEAPKPKVEEK 877
Query: 772 RDSSTQPPKSAKPPAGGKSSQQ----PSTPQQAP-------PGQPQQGTFVAHKEIKLTL 820
++ + + PK +K A + ++ P+ ++AP +P++ T VA KE
Sbjct: 878 KEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAK 937
Query: 821 LNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSK 880
+ + +K P KD + AK+P P ++ ++ L SK
Sbjct: 938 AKEPSKPAEKKEAAPEKKDTKE-EKAKKPEEKPKTEAKAKEDDKTL------------SK 984
Query: 881 APAAPADRKRQLSPQSKSSSKVTSVPGKASDPGAASTK 918
P+ P K + S S + K + P KA++ AA K
Sbjct: 985 EPSKPKAEKAEKS--SSTDQKDSKPPEKATEDKAAKGK 1020
Score = 100 bits (249), Expect = 6e-21
Identities = 130/587 (22%), Positives = 243/587 (41%), Gaps = 51/587 (8%)
Query: 404 RERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEW-ERERAKRDE 462
+ E+ + + E+E ++ E + E E E + KE + ++EE E E A+ E
Sbjct: 439 KSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGE 498
Query: 463 KDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWR-- 520
++ + + EKE P + P+ +A+ P+KE A + +VK ++ K P +
Sbjct: 499 EETKSPPAEEAASPEKEAKSPVKEEAKSPA-EAKSPEKEEAKSPAEVKSPEKAKSPAKEE 557
Query: 521 -----RSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSR 575
+KSP+K+ S + ++ + K+ A + S + S + ++S +
Sbjct: 558 AKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAE 617
Query: 576 SSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEK 635
+ S ++S S +++S + + SP SP + ++ E A P KA K
Sbjct: 618 AKSPVKEEAKSPAEVK-SPEKAKSPTKEEAKSPEKAKSPEKEEAKSP-EKAKSPVKAEAK 675
Query: 636 SVKKPAPP-----PAPPQA---TKTTAPVPEPTKPGDPREARRKER-------PARTPPR 680
S +K P +P +A K A PE K EA+ E+ A+TP +
Sbjct: 676 SPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEK 735
Query: 681 RRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVS 740
++ + S + S ++++L V S + + A + S E + + V
Sbjct: 736 AKSPVKEEAKSPEK-AKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVK 794
Query: 741 S-ASSRSPAPAQTRKEKGKSKKEDGVK-----EEKRKRDSSTQPPKSA---KPPAGGKSS 791
S ++SP + + + K++ VK EEK + +PPK A K PA K+
Sbjct: 795 SPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTE 854
Query: 792 QQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNT 851
++ + ++ P + V K+ + + K K+ E DK + P + P
Sbjct: 855 EKKDSKKEEAPKKEAPKPKVEEKK-EPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAK 913
Query: 852 SPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGKASD 911
+ K + +P+ + +K P+ PA+ K++ +P+ K + + KA
Sbjct: 914 VEVKEDAKPKEKTEVAKKEPDDAK---AKEPSKPAE-KKEAAPEKKDTKE-----EKAKK 964
Query: 912 PGAASTKSGKA----STLSRREELLKQLKAVEDAIA-RKRAKIPGKA 953
P KA TLS+ K KA + + +K +K P KA
Sbjct: 965 PEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKA 1011
Score = 76.6 bits (187), Expect = 1e-13
Identities = 118/569 (20%), Positives = 212/569 (37%), Gaps = 39/569 (6%)
Query: 420 ERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKD----RQHRDRDREKE 475
ER+R +R Q + +E + + + R +WE R+ +D + D +
Sbjct: 343 ERQRSELEDRHQADIASYQEAIQQLDAELRNTKWEMAAQLREYQDLLNVKMALDIEIAAY 402
Query: 476 REKEKGKP--KPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKS----PKKKL 529
R+ +G+ P P S PK + +T +VK ++ K + K ++
Sbjct: 403 RKLLEGEECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTE 462
Query: 530 GVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRH 589
V+ K + + S ++S + +
Sbjct: 463 ETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKE 522
Query: 590 SSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGE-PAPPPGKAGEK-SVKKPAPPPAPP 647
+ S + ++S + SP+ SP + K E +PP K+ EK K PA +P
Sbjct: 523 EAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPE 582
Query: 648 QA-------TKTTAPVPEPTKPGDP-REARRKERPARTPPRRRTLSGSGSGS-GSSYSGS 698
+A K+ A P K P +E + A++P + S + S + S +
Sbjct: 583 KAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPT 642
Query: 699 SSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTR-KEKG 757
++S + A S + V +E + A A ++SP A++ KE+
Sbjct: 643 KEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEA 702
Query: 758 KS--KKEDGVKEEKRKRDSSTQPPK-SAKPPAGGKS--SQQPSTPQQAPPGQPQQGTFVA 812
KS K + VKEE + + + P K AK P KS ++ +P++A + + V
Sbjct: 703 KSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVK 762
Query: 813 HKEIKLTLLNKA---ADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRG-SRDRKSGGRLGS 868
E K +A ADK K P ++ +SP AK P + ++ + S
Sbjct: 763 SPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKS 822
Query: 869 PKPERQRGQNSKAPAAPADRKRQLSP-----QSKSSSKVTSVPGKASDPGAASTKSGKAS 923
P E ++ Q K P + + +P + K SK P K + K A
Sbjct: 823 PVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAV 882
Query: 924 TLSRREELLKQLKAVEDAIARKRAKIPGK 952
+ ++ + + ED +K+ P K
Sbjct: 883 EKPKESKVEAKKEEAED---KKKVPTPEK 908
Score = 70.5 bits (171), Expect = 7e-12
Identities = 122/678 (17%), Positives = 234/678 (34%), Gaps = 110/678 (16%)
Query: 136 EEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESLEAAKEKKKEDDDGEI 195
EE V++ E E E+ E+ + T + V E+E EA +E+ KE++ GE
Sbjct: 441 EEKIKVVEKSEKETVIVEEQTEETQVT---------EEVTEEEEKEAKEEEGKEEEGGEE 491
Query: 196 DDGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKGNCTWGMNCRFIHPGVNDKGNYSLIT 255
++ E +++ + P++ P + +K +
Sbjct: 492 EEAEGGEEETK----SPPAEEAASPEKEAKSPVKEEAK---------------------S 526
Query: 256 KADPFPPNGAPPLGPHPLMPANPWGGPVVDEILPPPPPEPPTESAWERGLRHAKEVLKKA 315
A+ P P + P +E PP + P + AK +
Sbjct: 527 PAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEK-------EEAKSPAEVK 579
Query: 316 TIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVRDTVLEPYADPYYDYE 375
+ K + P EE + E+ E ++ P + + V E
Sbjct: 580 SPEKAKSPAKEEAKSPAEAKSPEKAKSPVKE-----EAKSPAEAKSPVKE---------- 624
Query: 376 IERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERERRQRERE 435
E + E ++ ++ + +E + E+ + +
Sbjct: 625 ---------------------------EAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEK 657
Query: 436 REREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQA 495
E + + + E E+AK K + + ++ K KE+ K ++ P +A
Sbjct: 658 EEAKSPEKAKSPVKAEAKSPEKAKSPVK-AEAKSPEKAKSPVKEEAKSPEKAKSPVKEEA 716
Query: 496 EPPKKEAATTGPQVKRADEWKDPWR-RSKSPKKKLGVSVSPSRARRRRKTSASSASASNS 554
+ P+K + + K ++ K P + +KSP+K + SP +A + S A
Sbjct: 717 KSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEK----AKSPEKA---KTLDVKSPEAKTP 769
Query: 555 SRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSP 614
++ +RS + ++S + S ++S SP
Sbjct: 770 AKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIP--KKEEVKSPVKEE 827
Query: 615 HRP-SIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQ--ATKTTAPVPEPTKPGDPREARRK 671
+P ++ K PP KA E+ K PA P + + K AP E KP + K
Sbjct: 828 EKPQEVKVK----EPPKKAEEE--KAPATPKTEEKKDSKKEEAPKKEAPKP----KVEEK 877
Query: 672 ERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDM 731
+ PA P+ + + + + + V + + A + +D
Sbjct: 878 KEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKK-EPDDA 936
Query: 732 YADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSS 791
A S + +P T++EK K +E E K K D T + +KP A + +
Sbjct: 937 KAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKA--EKA 994
Query: 792 QQPSTPQQAPPGQPQQGT 809
++ S+ Q P++ T
Sbjct: 995 EKSSSTDQKDSKPPEKAT 1012
Score = 69.3 bits (168), Expect = 2e-11
Identities = 104/552 (18%), Positives = 212/552 (38%), Gaps = 61/552 (11%)
Query: 49 EDEESAARGPSQEEEDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDR 108
+ EE+ EEE+ + EE+ E +++++E E T SP EE E++
Sbjct: 460 QTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEE---TKSPPAEEAASPEKEA 516
Query: 109 TSDLRDEASSVTR----ELDEHELDYDEEVPEE-PAPAVQE------------DEAEKAG 151
S +++EA S E +E + + + PE+ +PA +E +EA+
Sbjct: 517 KSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPA 576
Query: 152 AEDDEEKGEGTPREEGKAGVQSVGEKESLEAAKEKKKEDDDGEIDDGEIDDDDLEEGEVK 211
EK + +EE K+ ++ +++ KE+ K + + + ++ EVK
Sbjct: 577 EVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAK---SPVKEEAKSPAEVK 633
Query: 212 DPSDRKVRPRPTCRFFMKGNCTWGMNCRFIHPGVNDKGNYSLITKADPFPPNGAPPLGPH 271
P K + + K + + + S + P P+
Sbjct: 634 SPEKAKSPTKEEAKSPEKAKSPEKEEAK------SPEKAKSPVKAEAKSPEKAKSPVKAE 687
Query: 272 PLMPANPWGGPVVDEILPPPPPEPPTE---SAWERGLRHAKEVLK-----KATIRKE--- 320
P PV +E P + P + + E+ KE K K+ +++E
Sbjct: 688 AKSPEKA-KSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKS 746
Query: 321 -QEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVRDTVLEPYADPYYDYEIERF 379
++ EK T+ + E + + E R + P + V E P
Sbjct: 747 PEKAKSPEKAKTLDVKSPEAKTPAKEEA-RSPADKFPEKAKSPVKEEVKSP-------EK 798
Query: 380 WRGGQYENFRVQYTETEPYHNYRE--RERERERENRQRERERERERDRERERRQRERERE 437
+ E+ + E + +E E+ +E + +E ++ E ++ + E +++
Sbjct: 799 AKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKD 858
Query: 438 REHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPP----SR 493
+ E +++ K + E ++ EK ++ + +++E E +K P P P
Sbjct: 859 SKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKE 918
Query: 494 QAEPPKK-EAATTGPQVKRADEWKDP-WRRSKSPKKKLGVSVSPSRARRRRKTSASSASA 551
A+P +K E A P +A E P ++ +P+KK +A++ + + A A
Sbjct: 919 DAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKK---DTKEEKAKKPEEKPKTEAKA 975
Query: 552 SNSSRSSSRSSS 563
++ S+ S
Sbjct: 976 KEDDKTLSKEPS 987
Score = 64.3 bits (155), Expect = 5e-10
Identities = 110/521 (21%), Positives = 214/521 (41%), Gaps = 58/521 (11%)
Query: 4 AESPERDPHSPEDEE--QPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQE 61
A+SP + SPE EE P + + + ++ ++ + E+ +S A S E
Sbjct: 524 AKSPA-EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPE 582
Query: 62 EEDNHSDEEDRA-SEPKSQDQ-DSEVNELSRGPTS--SPCEEEGDEGEEDRTSDLRDEAS 117
+ + + EE ++ +E KS ++ S V E ++ P SP +EE E ++ + +A
Sbjct: 583 KAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPE---KAK 639
Query: 118 SVTRELDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEK 177
S T+E E E A + +++EA+ K E E+ K+ V++ E
Sbjct: 640 SPTKE---------EAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKA--EA 688
Query: 178 ESLEAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKGNCTWGMN 237
+S E AK KE E E ++E E K P K + + K
Sbjct: 689 KSPEKAKSPVKE----EAKSPEKAKSPVKE-EAKSPEKAKSPVKEEAKTPEKAKSPVKEE 743
Query: 238 CRFIHPGVNDKGNYSLITKADPFPPNGAPPLGPHPLMPANPW----GGPVVDEILPPPPP 293
+ + + +L K+ P P PA+ + PV +E+ P
Sbjct: 744 AKSPEKAKSPEKAKTLDVKS----PEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKA 799
Query: 294 EPPTE---SAWERGLRHAKEVLKKATIRKEQEPD----------FEEKRFTVTIGEDERE 340
+ P + A E+ + +EV K+ +++E++P EE++ T +E++
Sbjct: 800 KSPLKEDAKAPEKEIPKKEEV--KSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKK 857
Query: 341 FDKENEVFRDWNSRIPRDVRDTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHN 400
K+ E + P+ + EP + + ++E + + +V E E
Sbjct: 858 DSKKEEAPK---KEAPKPKVEEKKEPAVEKPKESKVEAKKEEAE-DKKKVPTPEKEAPAK 913
Query: 401 YRERERERERENRQ-RERERERERDRERERRQREREREREHERDKERQRRKEEWERERAK 459
+E + +E + ++E + + +E + ++E E + KE + +K E E+ K
Sbjct: 914 VEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPE---EKPK 970
Query: 460 RDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKK 500
+ K ++ D+ KE K K + +S + ++PP+K
Sbjct: 971 TEAKAKED-DKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEK 1010
Score = 56.2 bits (134), Expect = 1e-07
Identities = 109/591 (18%), Positives = 200/591 (33%), Gaps = 33/591 (5%)
Query: 113 RDEASSVTRELDEHELDYDEEVPEEPAPAVQEDEA-EKAGAEDDEEKGEGTPREEGKAGV 171
+ E +V E E EEV EE +E+E E+ G E++E +G + A
Sbjct: 449 KSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEE 508
Query: 172 QSVGEKESLEAAKEKKK---EDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFM 228
+ EKE+ KE+ K E E ++ + + + K P+ + + P +
Sbjct: 509 AASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPE 568
Query: 229 KGNCTWGMNCRFIHPGVNDKGNYSLITKADPFPPNGAPPLGPHPLMPANPWGGPVVDEIL 288
K + + + P P+ PA PV +E
Sbjct: 569 KEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEA-KSPVKEEAK 627
Query: 289 PPPPPEPPTESAWERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVF 348
P + P E A AK K + KE+ E+ + V + E + ++ +
Sbjct: 628 SPAEVKSP-EKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPV---KAEAKSPEKAKSP 683
Query: 349 RDWNSRIPRDVRDTVLEPYADP-YYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERE 407
++ P + V E P ++ + + V+ P + E
Sbjct: 684 VKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEE 743
Query: 408 RERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQH 467
+ + + E+ + D + + + E DK ++ K +E K EK +
Sbjct: 744 AKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSP-VKEEVKSPEKAKSP 802
Query: 468 RDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKK 527
+E + EK PK + P ++ E P++ P K+A+E K P KK
Sbjct: 803 L---KEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPP--KKAEEEKAPATPKTEEKK 857
Query: 528 KLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSS 587
+P + + K A + S + + + + + +
Sbjct: 858 DSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAK---KEEAEDKKKVPTPEKEAPAKV 914
Query: 588 RHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPP 647
+ + ++ P + P +P+ K E AP E+ KKP P
Sbjct: 915 EVKEDAKPKEKTEVAKKEPDDAKAKEPSKPA--EKKEAAPEKKDTKEEKAKKPEEKPKTE 972
Query: 648 QATKTTAPV--PEPTKPGDPREARRKERPART------PPRRRTLSGSGSG 690
K EP+KP +A + E+ + T PP + T + G
Sbjct: 973 AKAKEDDKTLSKEPSKP----KAEKAEKSSSTDQKDSKPPEKATEDKAAKG 1019
Score = 31.2 bits (69), Expect = 4.8
Identities = 24/64 (37%), Positives = 35/64 (54%), Gaps = 5/64 (7%)
Query: 688 GSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLAS-----PVSSA 742
G+G S +GSSS S + +SVSSVS++ S A + S D L++ V+ A
Sbjct: 33 GAGGTRSAAGSSSGFHSWTRTSVSSVSASPSRFRGAGAASSTDSLDTLSNGPEGCMVAVA 92
Query: 743 SSRS 746
+SRS
Sbjct: 93 TSRS 96
>gi|20070262 TNF receptor-associated factor 3 interacting protein 1
isoform 1 [Homo sapiens]
Length = 691
Score = 101 bits (252), Expect = 3e-21
Identities = 107/430 (24%), Positives = 191/430 (44%), Gaps = 46/430 (10%)
Query: 389 RVQYTETEPYHNYRERERERERE-----NRQRERERERER-----DRERERRQRERERER 438
R Q E + RE+++++E+ NR RE ERER + D ER++ + RER+R
Sbjct: 182 RKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDR 241
Query: 439 EHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRS---PQPPSRQA 495
+ ER KE + RK E +E+ + ++DR+ RDRD+ K+R++ + K S + +R+
Sbjct: 242 DSERKKETE-RKSEGGKEKERLRDRDRE-RDRDKGKDRDRRRVKNGEHSWDLDREKNREH 299
Query: 496 EPPKKEAATTGPQVKRADE--WKDPWRRSKSP-KKKLGVSVSPSRARRRRKTSASSASAS 552
+ P+K++A++G K+ + +KD +++ + S++ ++RR K S
Sbjct: 300 DKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKED 359
Query: 553 NSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSF-SSSPSPSPT 611
N S S S SG + ++ ++ S ++ + +S S S S S + P+PT
Sbjct: 360 NISAKSLDSIV---SGINNEPNQETTTSEIGTKEANINSTSISDDNSASLRCENIQPNPT 416
Query: 612 PSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEP--TKPGDPREAR 669
S + G AG+ + P P P + + +P P +P PR R
Sbjct: 417 EKQKGDS---TSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKR 473
Query: 670 RKERPARTPPRRRTLSGSGSGSGS----SYSGSSSRSRSLSVSSVSSVSSATS-SSSSAH 724
+ A R SGSG + S++ + V + +S + +A
Sbjct: 474 QDSMEALQMDR----SGSGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAV 529
Query: 725 SVDSEDMYADLASPVSSAS------SRSPAPAQTRK---EKGKSKKEDGVKEEKRKRDSS 775
++ E+ + L + +SP P + + E K++D V +E K +S
Sbjct: 530 ELEEEEKHGGLVKKILETKKDYEKLQQSPKPGEKERSLFESAWKKEKDIVSKEIEKLRTS 589
Query: 776 TQP-PKSAKP 784
Q KSA P
Sbjct: 590 IQTLCKSALP 599
Score = 41.2 bits (95), Expect = 0.005
Identities = 48/210 (22%), Positives = 81/210 (38%), Gaps = 29/210 (13%)
Query: 36 QDLDGAGVR---------ASDLEDEESAARGPSQEEEDNHSDEEDRASEPKSQDQDSEVN 86
Q+LD VR D D E R S++ + +EDR +P+ +D+D E
Sbjct: 147 QELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR--KPREKDKDKEKA 204
Query: 87 ELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVTRELDEHELDYDEEVPEE----PAPAV 142
+ + G EGE +R + ++ E D D E +E
Sbjct: 205 KENGG-------NRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGK 257
Query: 143 QEDEAEKAGAEDDEEKGEGTPREEGKAGVQS--VGEKESLEAAKEKKKEDDDGE----ID 196
+++ E D +KG+ R K G S + +++ E K +KK GE +
Sbjct: 258 EKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLS 317
Query: 197 DGEIDDDDLE-EGEVKDPSDRKVRPRPTCR 225
DG D E E E+ + + + + + R
Sbjct: 318 DGTFKDSKAETETEISTRASKSLTTKTSKR 347
Score = 37.7 bits (86), Expect = 0.051
Identities = 39/251 (15%), Positives = 95/251 (37%), Gaps = 21/251 (8%)
Query: 698 SSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKG 757
S R + V S +S + +D++++ + + + R A + R
Sbjct: 121 SDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSR 180
Query: 758 KSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIK 817
K+++ +KE+++ R+ K+ + GG ++ + +P
Sbjct: 181 DRKQKEELKEDRKPREKDKDKEKAKEN--GGNRHREGERERAKARARPDN---------- 228
Query: 818 LTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQ 877
+ D+G+R+R S++ +++ ++ RDR+ G + R+
Sbjct: 229 ----ERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKN 284
Query: 878 NSKAPAAPADRKRQLSPQSKSSSKVTSVPGKASDPGAASTKSGKASTLSRREELLKQLKA 937
+ ++ R+ K S+ + K SD +K+ + +S R K+
Sbjct: 285 GEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRAS-----KS 339
Query: 938 VEDAIARKRAK 948
+ +++R+K
Sbjct: 340 LTTKTSKRRSK 350
Score = 34.3 bits (77), Expect = 0.57
Identities = 66/371 (17%), Positives = 126/371 (33%), Gaps = 59/371 (15%)
Query: 428 ERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRS 487
E + R R E D + R +EE + D D + ++R ++R++++ + R
Sbjct: 135 EVKGRASLTSRSQELDNKNVR-EEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRK 193
Query: 488 PQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSAS 547
P+ + E K+ + +R + K R +K G + R+++T
Sbjct: 194 PREKDKDKEKAKENGGNRHREGER-ERAKARARPDNERQKDRGNRERDRDSERKKETERK 252
Query: 548 SASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPS 607
S R R R R + ++ HS + R ++R
Sbjct: 253 SEGGKEKERLRDRDRE-------RDRDKGKDRDRRRVKNGEHS-WDLDREKNREHD---- 300
Query: 608 PSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPRE 667
+P +GE S K G ++
Sbjct: 301 ----------------KPEKKSASSGEMSKK---------------------LSDGTFKD 323
Query: 668 ARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVD 727
++ + + ++L+ S S S + ++S S+ S+ S ++ + +
Sbjct: 324 SKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSGINNEPNQETTT 383
Query: 728 SEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAG 787
SE + ++S S A R E + EK+K DS++ A P AG
Sbjct: 384 SE--IGTKEANINSTSISDDNSASLRCENIQPNPT-----EKQKGDSTSDAEGDAGP-AG 435
Query: 788 GKSSQQPSTPQ 798
S+ P TP+
Sbjct: 436 QDKSEVPETPE 446
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 100 bits (248), Expect = 8e-21
Identities = 83/232 (35%), Positives = 114/232 (49%), Gaps = 29/232 (12%)
Query: 402 RERERER-ERENRQRERERERERDRER---ERRQREREREREHERDKERQRRKEEWERER 457
RE+ER+R ERE ++RE+ER R R +R RR R RER R R ++R+ + + +RER
Sbjct: 297 REKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDRER 356
Query: 458 AKRDEKDRQHRDRDREKER----EKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRAD 513
K +E+ R+ RDRD +KER EKE+ + + RS + SR KK + R D
Sbjct: 357 EKENERGRR-RDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDD 415
Query: 514 EWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSAS-SASASNSSRSSSRSSSYSGSGSSRS 572
+ R SK KK S S SR R+ R S S +A + SRS +SS + +S
Sbjct: 416 K-----RDSKKEKKH---SRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKS 467
Query: 573 RSRSSSYSSYSSRS-----------SRHSSFSGSRSRSRSFSSSPSPSPTPS 613
RS S S + S S+ S SRS+ RS S S S
Sbjct: 468 NKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQS 519
Score = 94.4 bits (233), Expect = 5e-19
Identities = 91/320 (28%), Positives = 142/320 (44%), Gaps = 40/320 (12%)
Query: 332 VTIGEDEREFDKENEVFRDWNSRIPRDVRDTVLEPYADPYYDYEIERFWRGGQYENFR-- 389
+TIGE R F + E F RIP V+ + + +I++ + G E R
Sbjct: 198 MTIGEMLRSFLTKLEWFSTLFPRIPVPVQKNIDQQIKTR--PRKIKKDGKEGAEEIDRHV 255
Query: 390 VQYTETEPYHNYRERERERERENRQRERER------ERERDRERERRQRERE-REREHER 442
+ P + R R +R RE +RE +RE+ER++ ERE +ERE ER
Sbjct: 256 ERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKER 315
Query: 443 DKER-------QRRKEEWERERAKRDEKDRQ--HRDRDREKEREKEKGKPKPRS------ 487
+ R +RR ER R++ +DR+ RDRDRE+E+E E+G+ + R
Sbjct: 316 RRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERG 375
Query: 488 ---PQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKT 544
+ R E K++ + + K+ E KD RR + K R ++ K
Sbjct: 376 NEREKERERSRERSKEQRSRGEVEEKKHKEDKDD-RRHRDDK----------RDSKKEKK 424
Query: 545 SASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSS 604
+ S S RS SRS + SRS+ +SS + + S S S SGS+ R+ S
Sbjct: 425 HSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEK 484
Query: 605 SPSPSPTPSPHRPSIRTKGE 624
S +PS + R++ +
Sbjct: 485 SKKREHSPSKEKSRKRSRSK 504
Score = 94.4 bits (233), Expect = 5e-19
Identities = 80/271 (29%), Positives = 125/271 (46%), Gaps = 28/271 (10%)
Query: 335 GEDEREFDKENEVFRDWNSRIPRDVRDTVLEPYADPYYDYEIERFWRGGQYENFRVQYTE 394
G FD+E E ++ R+ R+ ++ E D +ER + +
Sbjct: 285 GHGSSSFDRELEREKE-RQRLEREAKEREKERRRSRSIDRGLER------------RRSR 331
Query: 395 TEPYHNYRERERER--ERENRQRERERERERDRERER-------RQREREREREHERDKE 445
+ H R R R+R +R +R RERE+E ER R R+R +RE+ERER ER KE
Sbjct: 332 SRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKE 391
Query: 446 RQRRKEEWERERAKRDEKDRQHRD--RDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAA 503
QR + E E ++ K D+ DR+HRD RD +KE++ + + + R + SR K+ +
Sbjct: 392 -QRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRS 450
Query: 504 TTGPQ-VKRADEWKDPW-RRSKSPKKKLGVSVSPSRARRRRKTSASSASASNS-SRSSSR 560
+ + K +E K+ +RS+S + SV S+ R + S S S RS R
Sbjct: 451 RSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKR 510
Query: 561 SSSYSGSGSSRSRSRSSSYSSYSSRSSRHSS 591
S S S + R S S+ +H +
Sbjct: 511 DHSDSKDQSDKHDRRRSQSIEQESQEKQHKN 541
Score = 49.7 bits (117), Expect = 1e-05
Identities = 84/371 (22%), Positives = 131/371 (35%), Gaps = 89/371 (23%)
Query: 419 RERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDR------DR 472
+ R R +++ ++ E +R ER + R R+ R +R HR+ DR
Sbjct: 234 KTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDR 293
Query: 473 EKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVS 532
E EREKE+ Q R+A+ +KE RRS+S + L
Sbjct: 294 ELEREKER--------QRLEREAKEREKER-----------------RRSRSIDRGLERR 328
Query: 533 VSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSF 592
S SR R R ++ + R R + R R R Y R +
Sbjct: 329 RSRSRERHRSRSRSRDRKGDRRDRDREREKE-----NERGRRRDRDYDK-----ERGNER 378
Query: 593 SGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKT 652
R RSR S R++GE EK K+
Sbjct: 379 EKERERSRERSKEQ-------------RSRGE-------VEEKKHKEDKD---------- 408
Query: 653 TAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSS 712
+ D R+++++++ +R+ R R S S S ++ S SRS+ S +
Sbjct: 409 -----DRRHRDDKRDSKKEKKHSRSRSRERK-HRSRSRSRNAGKRSRSRSKEKSSKHKNE 462
Query: 713 VSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKR 772
++ S + S D V + R +P+ K KS+K KE KR
Sbjct: 463 SKEKSNKRSRSGSQGRTD-------SVEKSKKREHSPS-----KEKSRKRSRSKERSHKR 510
Query: 773 DSSTQPPKSAK 783
D S +S K
Sbjct: 511 DHSDSKDQSDK 521
Score = 45.8 bits (107), Expect = 2e-04
Identities = 42/190 (22%), Positives = 87/190 (45%), Gaps = 27/190 (14%)
Query: 302 ERGLRHAKEVLKKATIRKEQEPD-----FEEKRFTVTIGEDEREFDKENEVFRDWNSRIP 356
ERG R ++ K+ +E+E + +E+R + E + + DK++ RD
Sbjct: 361 ERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRD------ 414
Query: 357 RDVRDTVLEPYADPYYDYEIE-----RFWRGGQYENFRVQYTETEPYHNYRERERERERE 411
D RD+ E E + R G+ R + ++ + +E+ +R R
Sbjct: 415 -DKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRS 473
Query: 412 NRQR-----ERERERERDRERER-RQREREREREHERD----KERQRRKEEWERERAKRD 461
Q E+ ++RE +E+ R+R R +ER H+RD K++ + + + +++
Sbjct: 474 GSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQE 533
Query: 462 EKDRQHRDRD 471
+++QH+++D
Sbjct: 534 SQEKQHKNKD 543
Score = 41.6 bits (96), Expect = 0.004
Identities = 52/278 (18%), Positives = 104/278 (37%), Gaps = 15/278 (5%)
Query: 666 REARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHS 725
R RR P R+P R R+ S G GSSS R L +
Sbjct: 261 RSPRRSLSPRRSPRRSRSRSHHREG-----HGSSSFDRELEREKERQRLEREAKEREKER 315
Query: 726 VDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEK----RKRDSSTQPPKS 781
S + L S + R + +++R KG + D +E++ R+RD +
Sbjct: 316 RRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERG 375
Query: 782 AKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQ 841
+ + S++ S Q++ G+ ++ K+ + +K K +K ++R+
Sbjct: 376 NEREKERERSRERSKEQRS-RGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERK 434
Query: 842 SPPPAKRPNTSPDRGSRDRKSGGRLGSPKPER-----QRGQNSKAPAAPADRKRQLSPQS 896
++ N SR ++ + + E+ + G + + +KR+ SP
Sbjct: 435 HRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSK 494
Query: 897 KSSSKVTSVPGKASDPGAASTKSGKASTLSRREELLKQ 934
+ S K + ++ + +K RR + ++Q
Sbjct: 495 EKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQ 532
Score = 36.6 bits (83), Expect = 0.11
Identities = 40/174 (22%), Positives = 70/174 (40%), Gaps = 10/174 (5%)
Query: 55 ARGPSQEEEDNHSDEEDRASEPKSQDQ--DSEVNELSRGPTSSPCEEEGDEGEEDRTSDL 112
+R S E + S DR E + + Q + E E + S + G E R+ +
Sbjct: 276 SRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRE- 334
Query: 113 RDEASSVTRELDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQ 172
R + S +R+ D D E +E + + + D+E+G +E ++ +
Sbjct: 335 RHRSRSRSRDRKGDRRDRDREREKE------NERGRRRDRDYDKERGNEREKERERSRER 388
Query: 173 SVGEKESLEAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPS-DRKVRPRPTCR 225
S ++ E ++K KED D + D E+ + S +RK R R R
Sbjct: 389 SKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSR 442
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 99.4 bits (246), Expect = 1e-20
Identities = 58/151 (38%), Positives = 96/151 (63%), Gaps = 11/151 (7%)
Query: 386 ENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERE-RRQREREREREHERDK 444
E R + ++TE H+ R+R+R+RER NR+R+R+RERE+ +RE RQRERER+R+ +R+
Sbjct: 30 ERDRAKESKTEDRHSERDRQRDRER-NRERDRDREREKQTDREGERQRERERDRDRQRET 88
Query: 445 ERQRRKE-------EWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEP 497
ER+R KE E +RER K+ E++ + R RDRE+E++KE G+ + ++ + R+ E
Sbjct: 89 ERERDKERETDRHTETDRERQKQKEREME-RVRDREREKQKEMGRER-QTDRETDRERER 146
Query: 498 PKKEAATTGPQVKRADEWKDPWRRSKSPKKK 528
+ TG + K D ++ R K +++
Sbjct: 147 QAERERETGRERKTEDRHRERERERKRERER 177
Score = 95.5 bits (236), Expect = 2e-19
Identities = 67/209 (32%), Positives = 100/209 (47%), Gaps = 28/209 (13%)
Query: 389 RVQYTETEPYHNYRERERERERE----------------NRQRERERERERDRERERRQ- 431
R +TETE RER RE +RE +RQR+RER RERDR+RER +
Sbjct: 8 RHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQ 67
Query: 432 --REREREREHERDKERQRRKEEWERERAKRDEKDRQ-HRDRDREKEREKEKGKPKPRSP 488
RE ER+RE ERD++RQR E ERER K E DR DR+R+K++E+E + + R
Sbjct: 68 TDREGERQRERERDRDRQR---ETERERDKERETDRHTETDRERQKQKEREMERVRDRER 124
Query: 489 QPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASS 548
+ + + T + ++A+ ++ R K+ + R R R++ +
Sbjct: 125 EKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKER 184
Query: 549 ASASNSSRSSSRSSSYSGSGSSRSRSRSS 577
++ R R + R R R S
Sbjct: 185 ERHTDMERERQRETD-----RKRDRQRES 208
Score = 87.0 bits (214), Expect = 7e-17
Identities = 61/167 (36%), Positives = 95/167 (56%), Gaps = 15/167 (8%)
Query: 319 KEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVRDTVLEPYADPYYDYEIER 378
+E++ D E ++ T GE +RE +++ + R+ R+ E D + + + ER
Sbjct: 56 RERDRDREREKQTDREGERQRERERDRDRQRETE-------RERDKERETDRHTETDRER 108
Query: 379 FWRGGQYENFRVQYTETEPYHNY-RERERERERENRQRERERERERDRERERRQRERERE 437
+ + E RV+ E E RER+ +RE + R+RER+ ERER+ RER+ +R RE
Sbjct: 109 -QKQKEREMERVRDREREKQKEMGRERQTDRETD-RERERQAERERETGRERKTEDRHRE 166
Query: 438 REHERDKERQRRKEEWERERAKRDEKDRQH-----RDRDREKEREKE 479
RE ER +ER+R++E ERER E++RQ RDR RE ERE++
Sbjct: 167 RERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
Score = 77.8 bits (190), Expect = 4e-14
Identities = 70/218 (32%), Positives = 100/218 (45%), Gaps = 33/218 (15%)
Query: 298 ESAWERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPR 357
ES E H + + +E D E R + ED E + RD R
Sbjct: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHS---ERDRQRDRERNRER 58
Query: 358 DVRDTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERE------ 411
D RD E D + + ER E R + ETE RER++ERE
Sbjct: 59 D-RDREREKQTDREGERQRER-------ERDRDRQRETE-------RERDKERETDRHTE 103
Query: 412 -----NRQRERERERERDRERERRQ---REREREREHERDKERQ-RRKEEWERERAKRDE 462
+Q+ERE ER RDRERE+++ RER+ +RE +R++ERQ R+ E RER D
Sbjct: 104 TDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDR 163
Query: 463 KDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKK 500
+ R+R RE+ER++E + + + RQ E +K
Sbjct: 164 HRERERERKRERERKRETKERERHTDMERERQRETDRK 201
Score = 55.8 bits (133), Expect = 2e-07
Identities = 42/207 (20%), Positives = 74/207 (35%), Gaps = 30/207 (14%)
Query: 404 RERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEK 463
R E E R+RER RE DRER+R + + +R ERD++R R
Sbjct: 8 RHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRE-------------- 53
Query: 464 DRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSK 523
R+R+R+++RE+EK + Q + ++E + + D + R +
Sbjct: 54 ----RNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQ 109
Query: 524 SPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGS------------SR 571
K++ V ++++ + + R R + R
Sbjct: 110 KQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERER 169
Query: 572 SRSRSSSYSSYSSRSSRHSSFSGSRSR 598
R R + RH+ R R
Sbjct: 170 ERKRERERKRETKERERHTDMERERQR 196
Score = 35.0 bits (79), Expect = 0.33
Identities = 42/190 (22%), Positives = 73/190 (38%), Gaps = 18/190 (9%)
Query: 49 EDEESAARGPSQEEEDNHSDEEDRASEPKSQ--DQDSEVNELSRGPTSSPCEEEGDEGEE 106
E + R + ED HS+ + + +++ D+D E + + E E D +
Sbjct: 26 ETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQ 85
Query: 107 DRTSDLRDEASSVTRELDEH-ELDYD-EEVPEEPAPAVQEDEAEK---------AGAEDD 155
T RD+ RE D H E D + ++ E V++ E EK E D
Sbjct: 86 RETERERDK----ERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETD 141
Query: 156 EEKGEGTPREEGKAGVQSVGEKESLEAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSD 215
E+ RE + G + E E +E+K+E + D+E ++
Sbjct: 142 RERERQAERER-ETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDR 200
Query: 216 RKVRPRPTCR 225
++ R R + R
Sbjct: 201 KRDRQRESER 210
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 98.2 bits (243), Expect = 3e-20
Identities = 80/269 (29%), Positives = 127/269 (47%), Gaps = 33/269 (12%)
Query: 398 YHNYRERERERERE-------NRQRERERERERDRERERRQREREREREHERDKERQRRK 450
++ R R+++R R ++ RER + R R R++R+ RE+ +E ER KE+ R K
Sbjct: 338 HNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREK 397
Query: 451 EEWERERAKRDEKDR-QHRDRDREKEREKEKGKPKPRSPQ-----PPSRQAEPPK---KE 501
E ERE+ + EK+R +++DRD+E+E+++EK K K R + R E K KE
Sbjct: 398 ER-EREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKE 456
Query: 502 AATTGPQVKRADEWKDPWRRSKSPKKKLGV---SVSPSRARRRRKTSASSASASNSSRSS 558
+ K DE + ++S++P + S S SR RRRR+ S SS+ + +S++
Sbjct: 457 KEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRR-SRSSSRSPRTSKTI 515
Query: 559 SRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHR-- 616
R SS S S SR++ R S R R RS S S + +
Sbjct: 516 KRKSSRSPSPRSRNKKD-------KKREKERDHISERRERERSTSMRKSSNDRDGKEKLE 568
Query: 617 ---PSIRTKGEPAPPPGKAGEKSVKKPAP 642
S++ K P ++ K AP
Sbjct: 569 KNSTSLKEKEHNKEPDSSVSKEVDDKDAP 597
Score = 91.7 bits (226), Expect = 3e-18
Identities = 73/250 (29%), Positives = 108/250 (43%), Gaps = 46/250 (18%)
Query: 399 HNYRERERERERENRQRERERERERDRERER---------RQREREREREHERDKERQRR 449
H+ R+R + + R +R R R R++DR R + R+R + R R H RDK + R
Sbjct: 323 HSRRKRSQSKHR-SRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTR 381
Query: 450 KEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQV 509
++ E+ER K EKDR+ ++R+REKEREKEK + K + + KE +
Sbjct: 382 EKIKEKERVK--EKDRE-KEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERERE 438
Query: 510 KRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGS 569
K ++ +D + + K+K R RS
Sbjct: 439 KEHEKDRDKEKEKEQDKEK--------------------------EREKDRSKEIDEKRK 472
Query: 570 SRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPP 629
+SR+ S +SR SR SS R RSRS S SP S T I+ K +P P
Sbjct: 473 KDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKT-------IKRKSSRSPSP 525
Query: 630 GKAGEKSVKK 639
+K K+
Sbjct: 526 RSRNKKDKKR 535
Score = 81.3 bits (199), Expect = 4e-15
Identities = 64/230 (27%), Positives = 104/230 (45%), Gaps = 39/230 (16%)
Query: 402 RERERERERENRQRERERERERDRERER-------------------------RQRERER 436
R R + R + + R+R + + R R R+R + R
Sbjct: 309 RSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSR 368
Query: 437 EREHERDKERQRRKEEWERERAKRDEKDRQ-HRDRDREKEREKEKGKPKPRSPQPPSRQA 495
R H RDK + R++ E+ER K EKDR+ R+R++E+E+EKE+GK K R + +
Sbjct: 369 SRSHSRDKRKDTREKIKEKERVK--EKDREKEREREKEREKEKERGKNKDRDKEREKDRE 426
Query: 496 EPPKKEAATTGPQVKRADEWKDPWR---RSKSPKKKLGVSVSPSRAR-RRRKTSASSASA 551
+ +K+ + D K+ + + K +K + R + ++ +T S +A
Sbjct: 427 KDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNA 486
Query: 552 SNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRS 601
S SRSSSR R RSRSSS S +S++ + S RSR+
Sbjct: 487 SRRSRSSSRE-------RRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRN 529
Score = 74.7 bits (182), Expect = 4e-13
Identities = 47/176 (26%), Positives = 89/176 (50%), Gaps = 17/176 (9%)
Query: 402 RERERERERENRQRERERERERDRERERRQ-REREREREHERDKERQRRKEEWERERAKR 460
RE+++E++RE R+RE+E E++RD+E+E+ Q +E+ERE++ ++ + +R+K++ R +
Sbjct: 425 REKDKEKDRE-REREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRS 483
Query: 461 DEKDRQHRDRDREKEREKEKG------------KPKPRSPQPPSRQAEPPKKEAATTGPQ 508
R+ R RE+ R + + + RSP P SR + K+E
Sbjct: 484 YNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHIS 543
Query: 509 VKRADEWKDPWRRS---KSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRS 561
+R E R+S + K+KL + + + + K SS S + + R+
Sbjct: 544 ERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRT 599
Score = 70.1 bits (170), Expect = 9e-12
Identities = 86/341 (25%), Positives = 131/341 (38%), Gaps = 56/341 (16%)
Query: 482 KPKPRSPQPPSRQAEPPKKE--------AATTGPQVKRADEWKDPWRRSKSPKKKLGVSV 533
KP +PQ +++ E K +A P+ +++E K RS+S + S
Sbjct: 262 KPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGG--RSRSHTRSKSRSS 319
Query: 534 SPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGS---SRSRSRSSSYSSYSSRSSRHS 590
S S +RR+R S + + N SRS + S S S+SR R S S SR R
Sbjct: 320 SKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKD 379
Query: 591 SFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKG---------------EPAPPPGKAGEK 635
+ + + R R + +G + + EK
Sbjct: 380 TREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREK 439
Query: 636 SVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSY 695
+K + K + +K D E R+K++ +RTPPR S + S
Sbjct: 440 EHEKDRDKEKEKEQDKEKEREKDRSKEID--EKRKKDKKSRTPPR--------SYNASRR 489
Query: 696 SGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKE 755
S SSSR R S SS S TS + + SSRSP+P K+
Sbjct: 490 SRSSSRERRRRRSRSSSRSPRTSKT------------------IKRKSSRSPSPRSRNKK 531
Query: 756 KGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPST 796
K +KE E+R+R+ ST KS+ G + ++ ST
Sbjct: 532 DKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNST 572
Score = 47.4 bits (111), Expect = 6e-05
Identities = 41/208 (19%), Positives = 77/208 (37%), Gaps = 9/208 (4%)
Query: 294 EPPTESAWERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNS 353
E E ERG ++ ++ K++E D E +R E E++ DKE E +D
Sbjct: 402 EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREK----EHEKDRDKEKEKEQDKEK 457
Query: 354 RIPRDVRDTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENR 413
+D + E R Y R + + R R R
Sbjct: 458 EREKDRSKEIDEKRKKDKKSRTPPR-----SYNASRRSRSSSRERRRRRSRSSSRSPRTS 512
Query: 414 QRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDRE 473
+ + + R R +++++RE+E + ER+ R+ ++ D ++ +++
Sbjct: 513 KTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNST 572
Query: 474 KEREKEKGKPKPRSPQPPSRQAEPPKKE 501
+EKE K S + P+ E
Sbjct: 573 SLKEKEHNKEPDSSVSKEVDDKDAPRTE 600
Score = 43.1 bits (100), Expect = 0.001
Identities = 51/253 (20%), Positives = 96/253 (37%), Gaps = 16/253 (6%)
Query: 664 DPREARRKERPA-RTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSS 722
+P + ER R+ R+ S S S S S S S+ RS S + S S S
Sbjct: 294 EPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKS 353
Query: 723 AHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSA 782
H S+ + S + + + KEK + K++D KE +R+++ + +
Sbjct: 354 PHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK 413
Query: 783 KPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPS------ 836
+ + ++ + ++ H++ + K DK + + S
Sbjct: 414 NKDRDKEREKDREKDKEKDREREREKE---HEKDRDKEKEKEQDKEKEREKDRSKEIDEK 470
Query: 837 ---DKDRQSPPP---AKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKR 890
DK ++PP A R + S R R R+S SP+ + + S +P R +
Sbjct: 471 RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 530
Query: 891 QLSPQSKSSSKVT 903
+ + K ++
Sbjct: 531 KDKKREKERDHIS 543
Score = 41.2 bits (95), Expect = 0.005
Identities = 46/232 (19%), Positives = 92/232 (39%), Gaps = 22/232 (9%)
Query: 3 VAESPERDPHSPEDE--------EQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESA 54
+ + PE P + E + Q I +SG + G R S
Sbjct: 260 IVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSR--------SH 311
Query: 55 ARGPSQEEEDNHSDEEDRASEPKSQDQD-SEVNELSRGPTSSPCEEEGDEGEEDRT---S 110
R S+ +HS + S+ +S+ + S + R + SP ++ E ++ S
Sbjct: 312 TRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRS 371
Query: 111 DLRDEASSVTRELDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAG 170
RD+ ++ E E +++ +E + ++ ++ G D +K RE+ K
Sbjct: 372 HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEK 431
Query: 171 VQSVGEKESLEAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRP 222
+ ++ E ++K+KE + + + E + D +E + K D+K R P
Sbjct: 432 DREREREKEHEKDRDKEKEKEQDK--EKEREKDRSKEIDEKRKKDKKSRTPP 481
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 98.2 bits (243), Expect = 3e-20
Identities = 80/269 (29%), Positives = 127/269 (47%), Gaps = 33/269 (12%)
Query: 398 YHNYRERERERERE-------NRQRERERERERDRERERRQREREREREHERDKERQRRK 450
++ R R+++R R ++ RER + R R R++R+ RE+ +E ER KE+ R K
Sbjct: 222 HNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREK 281
Query: 451 EEWERERAKRDEKDR-QHRDRDREKEREKEKGKPKPRSPQ-----PPSRQAEPPK---KE 501
E ERE+ + EK+R +++DRD+E+E+++EK K K R + R E K KE
Sbjct: 282 ER-EREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKE 340
Query: 502 AATTGPQVKRADEWKDPWRRSKSPKKKLGV---SVSPSRARRRRKTSASSASASNSSRSS 558
+ K DE + ++S++P + S S SR RRRR+ S SS+ + +S++
Sbjct: 341 KEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRR-SRSSSRSPRTSKTI 399
Query: 559 SRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHR-- 616
R SS S S SR++ R S R R RS S S + +
Sbjct: 400 KRKSSRSPSPRSRNKKD-------KKREKERDHISERRERERSTSMRKSSNDRDGKEKLE 452
Query: 617 ---PSIRTKGEPAPPPGKAGEKSVKKPAP 642
S++ K P ++ K AP
Sbjct: 453 KNSTSLKEKEHNKEPDSSVSKEVDDKDAP 481
Score = 91.7 bits (226), Expect = 3e-18
Identities = 73/250 (29%), Positives = 108/250 (43%), Gaps = 46/250 (18%)
Query: 399 HNYRERERERERENRQRERERERERDRERER---------RQREREREREHERDKERQRR 449
H+ R+R + + R +R R R R++DR R + R+R + R R H RDK + R
Sbjct: 207 HSRRKRSQSKHR-SRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTR 265
Query: 450 KEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQV 509
++ E+ER K EKDR+ ++R+REKEREKEK + K + + KE +
Sbjct: 266 EKIKEKERVK--EKDRE-KEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERERE 322
Query: 510 KRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGS 569
K ++ +D + + K+K R RS
Sbjct: 323 KEHEKDRDKEKEKEQDKEK--------------------------EREKDRSKEIDEKRK 356
Query: 570 SRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPP 629
+SR+ S +SR SR SS R RSRS S SP S T I+ K +P P
Sbjct: 357 KDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKT-------IKRKSSRSPSP 409
Query: 630 GKAGEKSVKK 639
+K K+
Sbjct: 410 RSRNKKDKKR 419
Score = 81.3 bits (199), Expect = 4e-15
Identities = 64/230 (27%), Positives = 104/230 (45%), Gaps = 39/230 (16%)
Query: 402 RERERERERENRQRERERERERDRERER-------------------------RQRERER 436
R R + R + + R+R + + R R R+R + R
Sbjct: 193 RSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSR 252
Query: 437 EREHERDKERQRRKEEWERERAKRDEKDRQ-HRDRDREKEREKEKGKPKPRSPQPPSRQA 495
R H RDK + R++ E+ER K EKDR+ R+R++E+E+EKE+GK K R + +
Sbjct: 253 SRSHSRDKRKDTREKIKEKERVK--EKDREKEREREKEREKEKERGKNKDRDKEREKDRE 310
Query: 496 EPPKKEAATTGPQVKRADEWKDPWR---RSKSPKKKLGVSVSPSRAR-RRRKTSASSASA 551
+ +K+ + D K+ + + K +K + R + ++ +T S +A
Sbjct: 311 KDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNA 370
Query: 552 SNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRS 601
S SRSSSR R RSRSSS S +S++ + S RSR+
Sbjct: 371 SRRSRSSSRE-------RRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRN 413
Score = 74.7 bits (182), Expect = 4e-13
Identities = 47/176 (26%), Positives = 89/176 (50%), Gaps = 17/176 (9%)
Query: 402 RERERERERENRQRERERERERDRERERRQ-REREREREHERDKERQRRKEEWERERAKR 460
RE+++E++RE R+RE+E E++RD+E+E+ Q +E+ERE++ ++ + +R+K++ R +
Sbjct: 309 REKDKEKDRE-REREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRS 367
Query: 461 DEKDRQHRDRDREKEREKEKG------------KPKPRSPQPPSRQAEPPKKEAATTGPQ 508
R+ R RE+ R + + + RSP P SR + K+E
Sbjct: 368 YNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHIS 427
Query: 509 VKRADEWKDPWRRS---KSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRS 561
+R E R+S + K+KL + + + + K SS S + + R+
Sbjct: 428 ERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRT 483
Score = 70.1 bits (170), Expect = 9e-12
Identities = 86/341 (25%), Positives = 131/341 (38%), Gaps = 56/341 (16%)
Query: 482 KPKPRSPQPPSRQAEPPKKE--------AATTGPQVKRADEWKDPWRRSKSPKKKLGVSV 533
KP +PQ +++ E K +A P+ +++E K RS+S + S
Sbjct: 146 KPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGG--RSRSHTRSKSRSS 203
Query: 534 SPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGS---SRSRSRSSSYSSYSSRSSRHS 590
S S +RR+R S + + N SRS + S S S+SR R S S SR R
Sbjct: 204 SKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKD 263
Query: 591 SFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKG---------------EPAPPPGKAGEK 635
+ + + R R + +G + + EK
Sbjct: 264 TREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREK 323
Query: 636 SVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSY 695
+K + K + +K D E R+K++ +RTPPR S + S
Sbjct: 324 EHEKDRDKEKEKEQDKEKEREKDRSKEID--EKRKKDKKSRTPPR--------SYNASRR 373
Query: 696 SGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKE 755
S SSSR R S SS S TS + + SSRSP+P K+
Sbjct: 374 SRSSSRERRRRRSRSSSRSPRTSKT------------------IKRKSSRSPSPRSRNKK 415
Query: 756 KGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPST 796
K +KE E+R+R+ ST KS+ G + ++ ST
Sbjct: 416 DKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNST 456
Score = 47.4 bits (111), Expect = 6e-05
Identities = 41/208 (19%), Positives = 77/208 (37%), Gaps = 9/208 (4%)
Query: 294 EPPTESAWERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNS 353
E E ERG ++ ++ K++E D E +R E E++ DKE E +D
Sbjct: 286 EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREK----EHEKDRDKEKEKEQDKEK 341
Query: 354 RIPRDVRDTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENR 413
+D + E R Y R + + R R R
Sbjct: 342 EREKDRSKEIDEKRKKDKKSRTPPR-----SYNASRRSRSSSRERRRRRSRSSSRSPRTS 396
Query: 414 QRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDRE 473
+ + + R R +++++RE+E + ER+ R+ ++ D ++ +++
Sbjct: 397 KTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNST 456
Query: 474 KEREKEKGKPKPRSPQPPSRQAEPPKKE 501
+EKE K S + P+ E
Sbjct: 457 SLKEKEHNKEPDSSVSKEVDDKDAPRTE 484
Score = 43.1 bits (100), Expect = 0.001
Identities = 51/253 (20%), Positives = 96/253 (37%), Gaps = 16/253 (6%)
Query: 664 DPREARRKERPA-RTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSS 722
+P + ER R+ R+ S S S S S S S+ RS S + S S S
Sbjct: 178 EPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKS 237
Query: 723 AHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSA 782
H S+ + S + + + KEK + K++D KE +R+++ + +
Sbjct: 238 PHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK 297
Query: 783 KPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPS------ 836
+ + ++ + ++ H++ + K DK + + S
Sbjct: 298 NKDRDKEREKDREKDKEKDREREREKE---HEKDRDKEKEKEQDKEKEREKDRSKEIDEK 354
Query: 837 ---DKDRQSPPP---AKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKR 890
DK ++PP A R + S R R R+S SP+ + + S +P R +
Sbjct: 355 RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 414
Query: 891 QLSPQSKSSSKVT 903
+ + K ++
Sbjct: 415 KDKKREKERDHIS 427
Score = 41.2 bits (95), Expect = 0.005
Identities = 46/232 (19%), Positives = 92/232 (39%), Gaps = 22/232 (9%)
Query: 3 VAESPERDPHSPEDE--------EQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESA 54
+ + PE P + E + Q I +SG + G R S
Sbjct: 144 IVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSR--------SH 195
Query: 55 ARGPSQEEEDNHSDEEDRASEPKSQDQD-SEVNELSRGPTSSPCEEEGDEGEEDRT---S 110
R S+ +HS + S+ +S+ + S + R + SP ++ E ++ S
Sbjct: 196 TRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRS 255
Query: 111 DLRDEASSVTRELDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAG 170
RD+ ++ E E +++ +E + ++ ++ G D +K RE+ K
Sbjct: 256 HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEK 315
Query: 171 VQSVGEKESLEAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRP 222
+ ++ E ++K+KE + + + E + D +E + K D+K R P
Sbjct: 316 DREREREKEHEKDRDKEKEKEQDK--EKEREKDRSKEIDEKRKKDKKSRTPP 365
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 97.8 bits (242), Expect = 4e-20
Identities = 125/494 (25%), Positives = 196/494 (39%), Gaps = 78/494 (15%)
Query: 382 GGQYENFRVQYTETEPYHNYRERERER-ERENRQRERERERERDRERERRQREREREREH 440
G E +Q + + +E ERER ERE +RER ERER ERER +RER + +
Sbjct: 134 GPSQEELEIQRRQLQEQQRQKELERERLERERMERER-LERER-LERERLERERLEQEQL 191
Query: 441 ERDKERQRRKEEWER-ERAKRDEK-DRQHR-DRDREKEREKEKGKPKPRSPQPPSRQAEP 497
ER+++ + R+E ER ER +R E+ +RQ R DR+R++ +E+E+ + R Q RQ +
Sbjct: 192 ERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQL 251
Query: 498 PKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRS 557
+++ EW+ R R+ S+++A AS +
Sbjct: 252 EREQL-----------EWE-----------------------RERRISSAAAPASVETPL 277
Query: 558 SSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRS-----------RSRSFSSSP 606
+S SS S + S + S+ G + S + P
Sbjct: 278 NSVLGD-----SSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPP 332
Query: 607 SPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKT--TAPVPEPTKPGD 664
P P P P PS T P PPP + P PPPAPP A + E +P
Sbjct: 333 PPGPPPPPPLPS--TGPPPPPPPPPLPNQVPPPPPPPPAPPLPASGFFLASMSEDNRPLT 390
Query: 665 PREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRS--------LSVSSVSSVSSA 716
A R R S G+ + +SS++ + L S + SA
Sbjct: 391 GLAAAIAGAKLRKVSRMEDTSFPSGGNAIGVNSASSKTDTGRGNGPLPLGGSGLMEEMSA 450
Query: 717 --------TSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEE 768
S+ + ED D + PV+S +S + P TRK ++ +G K
Sbjct: 451 LLARRRRIAEKGSTIETEQKEDKGED-SEPVTSKASSTSTPEPTRKPWERTNTMNGSKSP 509
Query: 769 KRKRDSSTQPPKSAKPPAGGKSSQQP-STPQQAPPGQPQQGTFVAHKEIKLTLLNKAADK 827
R S + + S +P STP P Q + + +K +L++ +
Sbjct: 510 VISRRDSPRKNQIVFDNRSYDSLHRPKSTPLSQPSANGVQTEGLDYDRLKQDILDEMRKE 569
Query: 828 GSRKRYEPSDKDRQ 841
++ + E D RQ
Sbjct: 570 LTKLKEELIDAIRQ 583
Score = 36.2 bits (82), Expect = 0.15
Identities = 58/250 (23%), Positives = 88/250 (35%), Gaps = 25/250 (10%)
Query: 57 GPSQEE---EDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLR 113
GPSQEE + E+ R E + + + E E R E + E +R R
Sbjct: 134 GPSQEELEIQRRQLQEQQRQKELERERLERERMERER--------LERERLERERLERER 185
Query: 114 DEASSVTRELDEHE----LDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKA 169
E + RE E E L+ E + + QE + + E+ E RE +
Sbjct: 186 LEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQER 245
Query: 170 GVQSVGEKESLEAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDP---SDRKVRPRPTCRF 226
Q E+E LE +E++ + L + +P + + P+ +
Sbjct: 246 ERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQG 305
Query: 227 FMKGNCTWGMNCRFIHPGVNDKGNYSLITKADPFPPNGAPPLGPHPLMPANPWGGPVVDE 286
+ G P + + +L P PP P GP P P P V
Sbjct: 306 IVLGPLAPPPPPPL--PPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQV--- 360
Query: 287 ILPPPPPEPP 296
PPPPP PP
Sbjct: 361 --PPPPPPPP 368
Score = 32.0 bits (71), Expect = 2.8
Identities = 60/290 (20%), Positives = 108/290 (37%), Gaps = 33/290 (11%)
Query: 12 HSPEDEEQPQGLSDDDILRDSGSDQDLDG-AGVRASDLEDEESAARGPSQEEEDNH--SD 68
H D Q GL+ GS +D + A LE S GP+ +++ +
Sbjct: 78 HQWRDARQVYGLN-------FGSKEDANVFASAMMHALEVLNSQETGPTLPRQNSQLPAQ 130
Query: 69 EEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVTRELDEHEL 128
++ S+ + + Q ++ E R E E + E +R R E + RE E E
Sbjct: 131 VQNGPSQEELEIQRRQLQEQQRQK-----ELERERLERERMERERLERERLERERLERER 185
Query: 129 DYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESLEAAKEKKK 188
E++ E +++ E+ + +E+ E R + + Q E+E LE + +++
Sbjct: 186 LEQEQLERERQERERQERLERQERLERQERLERQERLDRER--QERQERERLERLERERQ 243
Query: 189 EDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKGNCTWGMNCRFIHPGVNDK 248
E + E LE +++ +R++ + +N ++
Sbjct: 244 ERERQE---------QLEREQLEWERERRISSAAA-----PASVETPLNSVLGDSSASEP 289
Query: 249 GNYSLITKADPFPPNGAP--PLGPHPLMPANPWGGPVVDEILPPPPPEPP 296
G + A+ G PL P P P P + PPP P PP
Sbjct: 290 GLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPP 339
Score = 31.6 bits (70), Expect = 3.7
Identities = 40/151 (26%), Positives = 54/151 (35%), Gaps = 6/151 (3%)
Query: 775 STQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAH-KEIKLTLLNKAADKGSRKRY 833
ST PP PP P P APP P G F+A E L AA K
Sbjct: 344 STGPPPPPPPPPLPNQVPPPPPPPPAPP-LPASGFFLASMSEDNRPLTGLAAAIAGAKLR 402
Query: 834 EPSDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLS 893
+ S + S P N + + GR P P G + A A R+R
Sbjct: 403 KVSRMEDTSFPSG--GNAIGVNSASSKTDTGRGNGPLPLGGSGLMEEMSALLARRRRIAE 460
Query: 894 PQSKSSSKVTSVPGKASDPGAASTKSGKAST 924
S ++ G+ S+P ++K+ ST
Sbjct: 461 KGSTIETEQKEDKGEDSEP--VTSKASSTST 489
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 97.1 bits (240), Expect = 7e-20
Identities = 96/417 (23%), Positives = 170/417 (40%), Gaps = 32/417 (7%)
Query: 389 RVQYTETEPYHNYRERERERERE---NRQRERERERERDRERER-RQREREREREHERDK 444
R + E E RERERERERE +++ERERERERDR+R+R ++R+R+R+RE +RD+
Sbjct: 310 RERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDR 369
Query: 445 ERQRRKE-EWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAA 503
+R+R + +R R++ +DR+ R+R+RE+ERE+E+ + + R + R+ E ++
Sbjct: 370 DRERSSDRNKDRSRSREKSRDRE-RERERERERERERERERERERE---RERERERERER 425
Query: 504 TTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSS 563
+ R ++ +D + R K ++KL + + R + + + R
Sbjct: 426 EKDKKRDREEDEEDAYERRKL-ERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEE 484
Query: 564 YSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGS------RSRSRSFSSSPSPSPTPSPHRP 617
+ ++ Y + GS R R + +
Sbjct: 485 RRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELE 544
Query: 618 SIR----TKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREAR---- 669
IR +G P P A + +++ A PQ + E + + E R
Sbjct: 545 EIRQRLLAEGHPDP---DAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPM 601
Query: 670 -RKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDS 728
+E P + P + TL S S + ++ + S + +S +
Sbjct: 602 EEEEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPGDESPCGIIIPHENSPDQQQPEE 661
Query: 729 EDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPP 785
L+ + +++S P Q K K D V + DS P K P
Sbjct: 662 HRPKIGLSLKLGASNS----PGQPNSVKRKKLPVDSVFNKFEDEDSDDVPRKRKLVP 714
Score = 96.7 bits (239), Expect = 9e-20
Identities = 58/167 (34%), Positives = 92/167 (55%), Gaps = 8/167 (4%)
Query: 384 QYENFRVQYTETEPYHNYRERERER-ERENRQRERERERERDRERERRQREREREREHER 442
+ FR + + E +E+ER+ E+E R+RERERERER+R R+RERERERE E+
Sbjct: 280 EISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEK 339
Query: 443 DKERQRRKEEWERERAKRDEKDR-QHRDRDREKEREKEKGKPKPRSPQPP-----SRQAE 496
++ER+R ++ +R+R K ++DR + RDRDR++ER ++ K + RS + R+ E
Sbjct: 340 ERERERERDR-DRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERE 398
Query: 497 PPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRK 543
++ + +R E + R + KK A RRK
Sbjct: 399 REREREREREREREREREREREREREREKDKKRDREEDEEDAYERRK 445
Score = 93.6 bits (231), Expect = 8e-19
Identities = 80/241 (33%), Positives = 121/241 (50%), Gaps = 16/241 (6%)
Query: 306 RHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVRDTVLE 365
+ +E+ K+ R+ + E+R E ERE +KE E R+ RD RD E
Sbjct: 300 KERQEIEKERRERERERERERERREREREREREREREKEKE--RERERERDRD-RDRTKE 356
Query: 366 PYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDR 425
D + + +R N + R+RERERERE R+RERERERER+R
Sbjct: 357 RDRDRDRERDRDRDRERSSDRN----KDRSRSREKSRDRERERERE-RERERERERERER 411
Query: 426 ERERRQREREREREHERDKERQRRKEE---WERERAKRDEKDRQHRDRDREKEREKEKGK 482
ERE R+RERERERE E+DK+R R ++E +ER + +R ++++ ++R K E + K
Sbjct: 412 ERE-REREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERK 470
Query: 483 PKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRR 542
K R + + + E ++E A + KR E+ + + + K S R R R
Sbjct: 471 -KTREYEKEAEREEERRREMA---KEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDRE 526
Query: 543 K 543
K
Sbjct: 527 K 527
Score = 63.2 bits (152), Expect = 1e-09
Identities = 68/277 (24%), Positives = 119/277 (42%), Gaps = 42/277 (15%)
Query: 302 ERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVRD 361
ER K+ + +++E + E +R E ERE ++E E R+ +D +
Sbjct: 372 ERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKR 431
Query: 362 TVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENR-QRERERE 420
E D Y ++ER R + Y E RER++ RE E +RE ER
Sbjct: 432 DREEDEEDAYERRKLERKLREKE-----AAYQERLKNWEIRERKKTREYEKEAEREEERR 486
Query: 421 RERDRERER-----------------------RQREREREREHERDKERQRRKEEWERER 457
RE +E +R ++R R+RE+E E D ER R++E+ E E
Sbjct: 487 REMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEAD-ERDRKREKEELEE 545
Query: 458 AKRDEKDRQHRDRDREKEREKEKG--KPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEW 515
++ H D D E +R +++ + +P+ Q P + E +K+ ++ ++
Sbjct: 546 IRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQ--------EKEEKR 597
Query: 516 KDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASAS 552
++P + P++K + P+ S SSAS +
Sbjct: 598 EEPMEEEEEPEQK--PCLKPTLRPISSAPSVSSASGN 632
Score = 48.5 bits (114), Expect = 3e-05
Identities = 37/139 (26%), Positives = 66/139 (47%), Gaps = 14/139 (10%)
Query: 405 ERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKD 464
E +R+ +R+ + R+ + E E+ ++E+ER+ E +KER+ R+ E ERER +R+
Sbjct: 271 EDKRDLISREISKFRDTHKKLEEEKGKKEKERQ---EIEKERRERERERERERERRE--- 324
Query: 465 RQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKS 524
RE+ERE+E+ + K + + + + + + D +D RS
Sbjct: 325 -------REREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDR-ERSSD 376
Query: 525 PKKKLGVSVSPSRARRRRK 543
K S SR R R +
Sbjct: 377 RNKDRSRSREKSRDRERER 395
Score = 41.2 bits (95), Expect = 0.005
Identities = 55/244 (22%), Positives = 94/244 (38%), Gaps = 37/244 (15%)
Query: 8 ERDPHSPEDEEQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQEEEDNHS 67
ER+ D ++ + D RD ++D D R+SD + S +R S++ E
Sbjct: 340 ERERERERDRDRDRTKERD---RDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERE 396
Query: 68 DEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRD--EASSVTRELDE 125
E +R E + + + E R E E D+ + DR D D E + R+L E
Sbjct: 397 RERERERERERERERERERERER---EREREREKDK-KRDREEDEEDAYERRKLERKLRE 452
Query: 126 HELDYDE-----EVPEEPAPAVQEDEAEKAGAEDDEEKGEG-----------TPREEGKA 169
E Y E E+ E E EAE+ E E R++ K
Sbjct: 453 KEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKY 512
Query: 170 GVQSVGEKESLEAAKEKKKEDDDGEIDDGEID------------DDDLEEGEVKDPSDRK 217
S +K + KE + ++ D + + E++ D D E ++ ++R+
Sbjct: 513 YRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERR 572
Query: 218 VRPR 221
+P+
Sbjct: 573 RQPQ 576
Score = 36.2 bits (82), Expect = 0.15
Identities = 45/181 (24%), Positives = 74/181 (40%), Gaps = 20/181 (11%)
Query: 48 LEDEESAARGP-------SQEEEDNHSDEEDRASEPKSQDQDSE----VNELSRGPTSSP 96
+E E R P S+EEE+ ++E++ EP ++++ E + R +S+P
Sbjct: 565 MEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAP 624
Query: 97 CEEEGDEGEEDRTSDLRDEASSVTRELDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDE 156
T DE S + HE D++ PEE P + + K GA +
Sbjct: 625 SVSSASGNATPNTPG--DE--SPCGIIIPHENSPDQQQPEEHRPKI--GLSLKLGASNSP 678
Query: 157 EKGEGTPREEGKAGVQSVGEKESLEAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSDR 216
+ R+ K V SV K E + + ++ +D GE DD + +G V R
Sbjct: 679 GQPNSVKRK--KLPVDSVFNKFEDEDSDDVPRKRKLVPLDYGE-DDKNATKGTVNTEEKR 735
Query: 217 K 217
K
Sbjct: 736 K 736
Score = 30.8 bits (68), Expect = 6.3
Identities = 39/196 (19%), Positives = 78/196 (39%), Gaps = 34/196 (17%)
Query: 51 EESAARGPSQEEEDNHSDEEDRASEPKSQDQ-------------DSEVNELSRGPTSSPC 97
++ A+ G ++ E + DEE E K +DQ SE+N S+ S P
Sbjct: 175 KKKASNGNARPETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPR 234
Query: 98 EEEGDEGEE-----------DRTSDLRDEASSVTRELDEHEL---------DYDEEVPEE 137
+++ ++ E+ +++ +++ E D+ +L D +++ EE
Sbjct: 235 KKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEE 294
Query: 138 PAPAVQE-DEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESLEAAKEKKKEDDDGEID 196
+E E EK E + E+ R E + + E+E + + +++ D D +
Sbjct: 295 KGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRT 354
Query: 197 DGEIDDDDLEEGEVKD 212
D D E +D
Sbjct: 355 KERDRDRDRERDRDRD 370
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 96.7 bits (239), Expect = 9e-20
Identities = 65/178 (36%), Positives = 102/178 (57%), Gaps = 22/178 (12%)
Query: 375 EIERFWRGGQYENFRVQYTETEPYHNYRERERERERE---NRQRERERERERDRERER-R 430
+ ER R Q + R + +T+ RE+ERER++E RQRERE ERE +R+RER R
Sbjct: 30 QTERENRHRQRDRHRERDRQTD-----REKERERQKERDRQRQRERETERETERQRERQR 84
Query: 431 QREREREREHERDKERQR-RKEEWERERAK-------RDEKDRQHRDRDREKEREKEKGK 482
QRER+R+ + ERDK+R R RK E +R R + RD++ + RDR+RE++R++E+ +
Sbjct: 85 QRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERER 144
Query: 483 PKPR-----SPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSP 535
+ R + + R AE +++ + K E K +R + K+K G +SP
Sbjct: 145 QRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGEGISP 202
Score = 81.6 bits (200), Expect = 3e-15
Identities = 54/162 (33%), Positives = 83/162 (51%), Gaps = 12/162 (7%)
Query: 402 RERERERERENRQRERERERERDRERERRQREREREREHERDKERQR---RKEEWERERA 458
RER+R+REREN+ R R+RDR RER R+ +RE+E ER KER R R+ E ERE
Sbjct: 19 RERDRQRERENQTERENRHRQRDRHRER-DRQTDREKERERQKERDRQRQRERETERETE 77
Query: 459 KRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDP 518
++ E+ RQ R+R R+ +RE++K + + R + R E +K Q +R + +
Sbjct: 78 RQRERQRQ-RERKRQTDRERDKDRDRERK-RETDRNRERNRKGGRERDKQTERERDRERE 135
Query: 519 WRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSR 560
+R + +++ R R+R A R R
Sbjct: 136 RQRQRERERQ------RQRERKRETDRERQRWAEREERKKER 171
Score = 70.9 bits (172), Expect = 5e-12
Identities = 57/170 (33%), Positives = 85/170 (50%), Gaps = 10/170 (5%)
Query: 298 ESAWERGLRHA-----KEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWN 352
E+ ER RH +E ++ KE+E E R E ERE +++ E R
Sbjct: 28 ENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRE 87
Query: 353 SRIPRD-VRDTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERE 411
+ D RD + D ER +GG+ + + + R+RERER+
Sbjct: 88 RKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQ-- 145
Query: 412 NRQRERERERERDRERERRQREREREREHERDKER-QRRKEEWERERAKR 460
RQRER+RE +R+R+R + ER++ER+ ER KER +++KEE RE KR
Sbjct: 146 -RQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKR 194
Score = 37.4 bits (85), Expect = 0.067
Identities = 39/191 (20%), Positives = 68/191 (35%), Gaps = 12/191 (6%)
Query: 2 DVAESPERDPHSPEDEEQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQE 61
D + ER+ + E + RD ++D R +D E E Q+
Sbjct: 12 DRGKETERERDRQRERENQTERENRHRQRDRHRERD------RQTDREKERER-----QK 60
Query: 62 EEDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVTR 121
E D E + ++ + + T +++ D + T R+ R
Sbjct: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
Query: 122 ELDEH-ELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESL 180
E D+ E + D E + + + E D E+ REE K + +KE
Sbjct: 121 ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERK 180
Query: 181 EAAKEKKKEDD 191
E KE+K+ +D
Sbjct: 181 EKKKEEKRRED 191
Score = 35.8 bits (81), Expect = 0.20
Identities = 36/176 (20%), Positives = 68/176 (38%), Gaps = 23/176 (13%)
Query: 431 QREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKERE---KEKGKPKPRS 487
+R+RER+RE +R KE +R E+DRQ R+R+ + ERE +++ + + R
Sbjct: 2 ERQRERKRETDRGKETER-------------ERDRQ-RERENQTERENRHRQRDRHRERD 47
Query: 488 PQ---PPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKT 544
Q R+ + + + +R E + +R + K++ R R R++
Sbjct: 48 RQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRE 107
Query: 545 SASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSR 600
+ + + + R R R R + + R R R
Sbjct: 108 TDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRET---DRERQR 160
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 95.5 bits (236), Expect = 2e-19
Identities = 94/329 (28%), Positives = 142/329 (43%), Gaps = 29/329 (8%)
Query: 389 RVQYTETEPYHNYRERERERERENRQRERERERERDRERER-RQREREREREHERDKERQ 447
R Y+ + + R R R R++R R + + R R R R R + R + R
Sbjct: 182 RRSYSRSRSHSRSRSRSRH-SRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRS 240
Query: 448 RRKEEWERERAKRDEKDRQH---RDRDREKEREKEK-------GKPKPRSPQPPSRQAEP 497
R K+E R +K + R H + R + K++ +EK GKPK RSP SR
Sbjct: 241 RSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSP---SRHKSK 297
Query: 498 PKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRS 557
K + + +V+ +E + R +S +K L S S SR++ ++ + S S S R
Sbjct: 298 SKSRSRSQERRVE--EEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRK 355
Query: 558 SSRSSSYSGSGSSRSRSRSS-SYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHR 616
+ S SRSRS+S S S R S+ S + S S SPS + S R
Sbjct: 356 GRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKER 415
Query: 617 PSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPAR 676
K E + G+ ++ Q T++ + +KP P E+R + + A
Sbjct: 416 E--HAKSESSQREGRGESENA-------GTNQETRSRSRSNSKSKPNLPSESRSRSKSA- 465
Query: 677 TPPRRRTLSGSGSGSGS-SYSGSSSRSRS 704
+ R R+ S S S S S S S S S SRS
Sbjct: 466 SKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 81.6 bits (200), Expect = 3e-15
Identities = 82/333 (24%), Positives = 131/333 (39%), Gaps = 21/333 (6%)
Query: 424 DRERERRQREREREREHERDKERQR--RKEEWERERAKRDEKDRQHRDRDREKEREKEKG 481
D+ RR+R R R H R + R R RK +K + R R + R K +
Sbjct: 175 DKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRS 234
Query: 482 KPKPRSPQPPSRQAEPPKKEAATTGPQV-KRADEWKDPWRRSKSPKKKLGVSVSPSRARR 540
+ + RS + P K+++ + K + KD +G S S +R
Sbjct: 235 RSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRH 294
Query: 541 RRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSR 600
+ K+ + S S R S SR RS S SRS R S GSRSRSR
Sbjct: 295 KSKSKSRSRSQERRVEEEKRGSV--------SRGRSQEKSLRQSRS-RSRSKGGSRSRSR 345
Query: 601 SFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPT 660
S S S R R++ ++ ++ K+ + + + K +
Sbjct: 346 SRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSR 405
Query: 661 KPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSS 720
P R ++ A++ +R G +G++ + SRSRS S S + S + S S
Sbjct: 406 SPS--RSVSKEREHAKSESSQREGRGESENAGTNQE-TRSRSRSNSKSKPNLPSESRSRS 462
Query: 721 SSAHSVDSEDMYADLASPVSSASSRSPAPAQTR 753
SA S + S ++SRSP+ +++R
Sbjct: 463 KSASKTRSR------SKSRSRSASRSPSRSRSR 489
Score = 79.7 bits (195), Expect = 1e-14
Identities = 94/306 (30%), Positives = 128/306 (41%), Gaps = 31/306 (10%)
Query: 511 RADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSS 570
R E K RR +S + S S SR+R RK+ + S S S SS S SRS S SGS
Sbjct: 171 RLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGS-SKSSHSKSRSRSRSGS--- 226
Query: 571 RSRSRSSSYSSYSSRSSRHSSFSGS--RSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPP 628
RSRS+S S S SRS + S S S +SRSRS S+ S S + I+ P
Sbjct: 227 RSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKP 286
Query: 629 PGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPAR-TPPRRRTLSGS 687
++ + K +++ E K G R +E+ R + R R+ GS
Sbjct: 287 KSRSPSRHKSK------SKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGS 340
Query: 688 GSGSGS---------------SYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDM- 731
S S S S S SRSRS S S S S + S+ ED
Sbjct: 341 RSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTD 400
Query: 732 YADLASPVSSAS-SRSPAPAQTRKEKGKSKKED-GVKEEKRKRDSSTQPPKSAKPPAGGK 789
+ SP S S R A +++ + +G+ + E+ G +E R R S K P
Sbjct: 401 RSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRS 460
Query: 790 SSQQPS 795
S+ S
Sbjct: 461 RSKSAS 466
Score = 74.3 bits (181), Expect = 5e-13
Identities = 95/368 (25%), Positives = 139/368 (37%), Gaps = 37/368 (10%)
Query: 522 SKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSS 581
S S K+ + + R+ S RS SRS S+S S S SR S S
Sbjct: 149 SYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRS 208
Query: 582 YSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPA 641
SS+SS S S SRS SRS S S S S + S R+K E + P K +S A
Sbjct: 209 GSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRS------RSKKEKSRSPSKEKSRSRSHSA 262
Query: 642 PPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGS---------G 692
+ + G P+ +R+P R ++ S S S S
Sbjct: 263 GKSRSKSKDQAEEKIQNNDNVGKPK--------SRSPSRHKSKSKSRSRSQERRVEEEKR 314
Query: 693 SSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQT 752
S S S+ +SL S S S S S S S+D + SRS + +++
Sbjct: 315 GSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKS 374
Query: 753 -RKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFV 811
R K SK++ K+K+ T +S P S+ S ++ + Q
Sbjct: 375 ERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSP------SRSVSKEREHAKSESSQREGR 428
Query: 812 AHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDR-KSGGRLGSPK 870
E N ++ +R R + K + + P R + +R R KS R S
Sbjct: 429 GESE------NAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRS 482
Query: 871 PERQRGQN 878
P R R ++
Sbjct: 483 PSRSRSRS 490
Score = 62.8 bits (151), Expect = 1e-09
Identities = 74/292 (25%), Positives = 121/292 (41%), Gaps = 24/292 (8%)
Query: 680 RRRTLSGSGSGSGS-SYSGSSSRSRSLSVSSVSSVSSATSSS-SSAHSVDSEDMYADLAS 737
RRR+ S S S S S S S S +SRS S SS SS S + S S S + S + S
Sbjct: 181 RRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRS 240
Query: 738 PVSSASSRSPAPAQTRKE-----KGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQ 792
SRSP+ ++R K +SK +D EEK + + + PKS P S+
Sbjct: 241 RSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQA-EEKIQNNDNVGKPKSRSPSRHKSKSK 299
Query: 793 QPSTPQQAPPGQPQQGTFVAHKEIKLTL---LNKAADKG---SRKRYEPSDKDRQSPPPA 846
S Q+ + ++G+ + + +L +++ KG SR R KD++
Sbjct: 300 SRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKR 359
Query: 847 KRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSP---------QSK 897
R + SR + R K + + G + K DR + SP +K
Sbjct: 360 SREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAK 419
Query: 898 SSSKVTSVPGKASDPGA-ASTKSGKASTLSRREELLKQLKAVEDAIARKRAK 948
S S G++ + G T+S S + L + ++ + ++ R++
Sbjct: 420 SESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSR 471
Score = 35.8 bits (81), Expect = 0.20
Identities = 33/164 (20%), Positives = 71/164 (43%), Gaps = 8/164 (4%)
Query: 796 TPQQAPPGQPQQGT--FVAHKEIKLTL--LNKAADKGSRKRY---EPSDKDRQSPPPAKR 848
T A G+ +G FV++ ++K L L+ G + R +P + R+S ++
Sbjct: 131 TYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRS 190
Query: 849 PNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGK 908
+ S R RKS R GS K + ++ + + K + QS+S SK
Sbjct: 191 HSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSP 250
Query: 909 ASDPGAASTKSGKASTLSRREELLKQLKAVEDAIARKRAKIPGK 952
+ + + + S S +++ ++++ D + + +++ P +
Sbjct: 251 SKEKSRSRSHSAGKSRSKSKDQAEEKIQN-NDNVGKPKSRSPSR 293
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 95.1 bits (235), Expect = 3e-19
Identities = 195/947 (20%), Positives = 306/947 (32%), Gaps = 177/947 (18%)
Query: 55 ARGPSQEEEDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRD 114
A P E + E S P S E EEE +E EE + +
Sbjct: 237 AYSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISR 296
Query: 115 EASSVTRELDEHELDYD---EEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGV 171
+ ++ D++ L D +E P A Q A + D + +G R V
Sbjct: 297 ISETLAGIYDDNSLSQDFPGDESPRPDAQPTQPTPAPGTPPQVDSTRADGAMRRR----V 352
Query: 172 QSVGEKESLEAAKEKKKEDDDGEIDDGEI-------DDDDLEEGEVKDPSDRKVRPRPTC 224
VG + EA +E K + + D ++EEGE+ P + PR
Sbjct: 353 FVVGTE--AEACREGKVSVEVVTAGGAALPPPLLPPGDSEIEEGEIVQPEE---EPRLAL 407
Query: 225 RFFMKGNCTWGMNCRFIHPGVNDKGNYSLITKADPFPPNGAPPLGPHPL-MPANPWGGPV 283
F G R P + + + P PP P G L + A G
Sbjct: 408 SLFRPGG-------RAARP--TPAASATPTAQPLPQPPAPRAPEGDDFLSLHAESDGEGA 458
Query: 284 VDEILPPPPPEPPTESAWERGLRHAKEVL--KKATIRKEQEPDFEEKRFTVTIGEDEREF 341
+ L P P PP + GL +++L ++ R+ G R+
Sbjct: 459 LQVDLGEPAPAPPAADSRWGGLDLRRKILTQRRERYRQRSPSPAPAPAPAAAAGPPTRKK 518
Query: 342 DKENEVFRDWNSRIPRDVRDTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNY 401
+ T P A P ++ ++ R + + +
Sbjct: 519 SRRERKRSGEAKEAASSSSGTQPAPPA-PASPWDSKK-------HRSRDRKPGSHASSSA 570
Query: 402 RERERERERENRQRERERERERDRERERRQREREREREHER---------DKERQRRKEE 452
R R R R R R R R +R R RR R RE+ R R RR+
Sbjct: 571 RRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPPPATSSSSSSRRERH 630
Query: 453 WERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRA 512
+ R K ++ R R R ++R + + P PPS +++ G
Sbjct: 631 RGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCGDRDSRRRGAVPPSI 690
Query: 513 DEWKD-----------PWRRSKSPKKKLGVSVSPSRARRRR--KTSASSASASNSSRSSS 559
+ D R KS + G S +P+ + +R S + +SS
Sbjct: 691 QDLTDHDLFAIKRTITVGRLDKSDPR--GPSPAPASSPKREVLYDSEGLSGEERGGKSSQ 748
Query: 560 RSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSI 619
+ SG+ SS S SR S R + G R R R R
Sbjct: 749 KDRRRSGAASSSSSSREKG-------SRRKALDGGDRDRDR------------DRDRDRD 789
Query: 620 RTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPP 679
R+ + PP ++S PPP PP +
Sbjct: 790 RSSKKARPP-----KESAPSSGPPPKPPVS------------------------------ 814
Query: 680 RRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYA------ 733
SGSGS SS S SSR L + SS++ A S + +
Sbjct: 815 -------SGSGSSSSSSSCSSRKVKLQSKVAVLIREGVSSTTPAKDAASAGLGSIGVKFS 867
Query: 734 ---DLASPVSSASSRSP------APAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKP 784
+ SP R+P AP T+ +K K K + G K+ K + T+P K+ K
Sbjct: 868 RDRESRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKAKAGAKKTKGTK-GKTKPSKTRKK 926
Query: 785 -----PAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKD 839
+GG Q +A GT K A++ S E + K
Sbjct: 927 VRSGGGSGGSGGQVSLKKSKADSCSQAAGT-------------KGAEETSWSGEERAAKV 973
Query: 840 RQSPPPAKR---PNTSPDRGSRD----------------RKSGGRLGSPKPERQRGQNSK 880
+PPP P +PD + D ++G R G+ + E + + +
Sbjct: 974 PSTPPPKAAPPPPALTPDSQTVDSSCKTPEVSFLPEEATEEAGVRGGAEEEEEEEEEEEE 1033
Query: 881 APAAPADRKRQLSPQSKSSSKVTSVPGKASDPGAASTKSGKASTLSR 927
+ + S +++ ++ P S G + + G AS +S+
Sbjct: 1034 EEEEEEQQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDGPASRVSQ 1080
Score = 73.6 bits (179), Expect = 8e-13
Identities = 142/597 (23%), Positives = 202/597 (33%), Gaps = 117/597 (19%)
Query: 433 EREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPS 492
E E E E E ++E +EE + R + D ++ P SP+P +
Sbjct: 269 EEEEEEEEEEEEEEDEEEEEGLSQSISRISETLAGIYDDNSLSQDF----PGDESPRPDA 324
Query: 493 RQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASAS 552
+ +P A T PQV D R + ++++ V + + A R K S +A
Sbjct: 325 QPTQPTP--APGTPPQV-------DSTRADGAMRRRVFVVGTEAEACREGKVSVEVVTAG 375
Query: 553 NSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTP 612
++ G S R + G R+ + ++S +P+ P
Sbjct: 376 GAALPPPLLPP----GDSEIEEGEIVQPEEEPRLALSLFRPGGRAARPTPAASATPTAQP 431
Query: 613 SPHRPSIRT-KGEP-----APPPGKAGEKSVKKPAPPPAPP------------------- 647
P P+ R +G+ A G+ G V P PAPP
Sbjct: 432 LPQPPAPRAPEGDDFLSLHAESDGE-GALQVDLGEPAPAPPAADSRWGGLDLRRKILTQR 490
Query: 648 -----QATKTTAPVPEPTKPGDP--REARRKER--------------------PARTPP- 679
Q + + AP P P P R+ R+ER PA P
Sbjct: 491 RERYRQRSPSPAPAPAPAAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQPAPPAPASPW 550
Query: 680 -----RRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVS-SVSSATSSSSSAHSVDSEDMYA 733
R R S S+ S SRSRS S S S S + S +
Sbjct: 551 DSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRR 610
Query: 734 DLASPVSSASSRSPAPAQTRKEK-------GKSKKEDGVKEEKRKRDSSTQPPKSAKPPA 786
ASP + SS S + + + K K KK + EKR D S + P A PP+
Sbjct: 611 RSASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPS 670
Query: 787 GGKS-SQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPP 845
G S + S + A P Q T IK T+ DK SD SP P
Sbjct: 671 GSTSCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGRLDK--------SDPRGPSPAP 722
Query: 846 AKRPN----------TSPDRG----SRDRKSGGRLGSPKPERQRGQNSKA-PAAPADRKR 890
A P + +RG +DR+ G S R++G KA DR R
Sbjct: 723 ASSPKREVLYDSEGLSGEERGGKSSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDR 782
Query: 891 QLSPQSKSSSKVT-----SVPGKASDP----GAASTKSGKASTLSRREELLKQLKAV 938
SSK S P P + S S +S+ S R+ L+ AV
Sbjct: 783 DRDRDRDRSSKKARPPKESAPSSGPPPKPPVSSGSGSSSSSSSCSSRKVKLQSKVAV 839
Score = 50.1 bits (118), Expect = 1e-05
Identities = 87/372 (23%), Positives = 121/372 (32%), Gaps = 79/372 (21%)
Query: 603 SSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPP-----------QATK 651
S+S SPSP+PS PS P PPP P PPAPP +
Sbjct: 192 SASSSPSPSPSSSSPS------PPPPP---------PPPAPPAPPAPRFDIYDPFHPTDE 236
Query: 652 TTAPVPEPTKPGDPRE--ARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSS 709
+P P P + DP E A TP S S+S
Sbjct: 237 AYSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISR 296
Query: 710 VSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEK 769
+S + +S S+D D SP A P PA + S + DG +
Sbjct: 297 ISETLAGIYDDNSL----SQDFPGD-ESPRPDAQPTQPTPAPGTPPQVDSTRADGAMRRR 351
Query: 770 -----RKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPG--QPQQGTFVAHKEIKLTLLN 822
+ ++ + S + G ++ P PPG + ++G V +E L+
Sbjct: 352 VFVVGTEAEACREGKVSVEVVTAGGAALPPPL---LPPGDSEIEEGEIVQPEEEPRLALS 408
Query: 823 KAADKGSRKRYEPSDKDRQS-----PPPAKRPNTSPDRGSRDRKSGGR------LGSPKP 871
G R P+ + PPA R D S +S G LG P P
Sbjct: 409 LFRPGGRAARPTPAASATPTAQPLPQPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAP 468
Query: 872 -----------------------ERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGK 908
ER R ++ APA P K S + G+
Sbjct: 469 APPAADSRWGGLDLRRKILTQRRERYRQRSPSPAPAPAPAAAAGPPTRKKSRRERKRSGE 528
Query: 909 ASDPGAASTKSG 920
A + AAS+ SG
Sbjct: 529 AKE--AASSSSG 538
Score = 40.0 bits (92), Expect = 0.010
Identities = 49/217 (22%), Positives = 72/217 (33%), Gaps = 38/217 (17%)
Query: 606 PSPSPTPS--PHRPSIRTKGEPAPPPGKAGEKSVKK----------PAPPPAPPQATKTT 653
P P P PS P + RT G+ P + + + PAPPPAP A+ +
Sbjct: 139 PIPLPVPSLLPRLRAWRT-GKTVSPQSNSSRPTCARHLTLGTGDGGPAPPPAPSSASSSP 197
Query: 654 APVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSV 713
+P P + P P PA PR +
Sbjct: 198 SPSPSSSSPSPPPPPPPPAPPAPPAPR------------------------FDIYDPFHP 233
Query: 714 SSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRD 773
+ S A + ++P SSA + SP + +E+ + ++ED +EE +
Sbjct: 234 TDEAYSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQS 293
Query: 774 SSTQPPKSAKPPAGGKSSQQ-PSTPQQAPPGQPQQGT 809
S A SQ P P QP Q T
Sbjct: 294 ISRISETLAGIYDDNSLSQDFPGDESPRPDAQPTQPT 330
Score = 33.9 bits (76), Expect = 0.74
Identities = 18/60 (30%), Positives = 31/60 (51%), Gaps = 3/60 (5%)
Query: 51 EESAARGPSQEEEDNHSDEEDRASEPKSQD-QDSEVNELSRGPTSSPC--EEEGDEGEED 107
EE+ RG ++EEE+ +EE+ E + Q + + + P+++P GD G ED
Sbjct: 1013 EEAGVRGGAEEEEEEEEEEEEEEEEEEQQPATTTATSTAAAAPSTAPSAGSTAGDSGAED 1072
Score = 32.7 bits (73), Expect = 1.7
Identities = 36/139 (25%), Positives = 50/139 (35%), Gaps = 17/139 (12%)
Query: 259 PFPPNGAPPLGPHPLMPANPWGGPVVDEILPPPPPEPPTESAWERGLRHAKEVLKKATIR 318
P PP APP P P P + PPP PE + G + T
Sbjct: 210 PPPPPPAPPAPPAPRFDIYDPFHPTDEAYSPPPAPEQKYDPFEPTGSNPSSSA---GTPS 266
Query: 319 KEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVRDTVLEPYADPYYDYEIER 378
E+E + EE+ E+E E ++E E SRI E A Y D + +
Sbjct: 267 PEEEEEEEEEE------EEEEEDEEEEEGLSQSISRIS--------ETLAGIYDDNSLSQ 312
Query: 379 FWRGGQYENFRVQYTETEP 397
+ G + Q T+ P
Sbjct: 313 DFPGDESPRPDAQPTQPTP 331
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 94.4 bits (233), Expect = 5e-19
Identities = 117/464 (25%), Positives = 182/464 (39%), Gaps = 73/464 (15%)
Query: 402 RERERERERENRQRERERERERDRERERRQRER-ERER----EHERDKERQRRKEEWER- 455
+E++R++E E + ERER ERER +RER ERER + ER+++ + R+E ER
Sbjct: 148 QEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQERERQERLERQ 207
Query: 456 ERAKRDEK-DRQHR-DRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRAD 513
ER +R E+ +RQ R DR+R++ +E+E+ + R Q RQ + +++
Sbjct: 208 ERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLEREQL----------- 256
Query: 514 EWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSR 573
EW+ R R+ S+++A AS + +S SS S
Sbjct: 257 EWE-----------------------RERRISSAAAPASVETPLNSVLGD-----SSASE 288
Query: 574 SRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAG 633
+ S + S+ G + P P P P + S+ P PPP
Sbjct: 289 PGLQAASQPAETPSQQGIVLG------PLAPPPPPPLPPGPAQASVALPPPPGPPP-PPP 341
Query: 634 EKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGS 693
S P PPP PP + P P P P P A R L+G +
Sbjct: 342 LPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPASGFFL---ASMSEDNRPLTGLAAAIAG 398
Query: 694 SYSGSSSRSRSLSVSS------VSSVSSATSSSSS------AHSVDSEDMYADLASPVSS 741
+ SR S S V+S SS T + S E+M A LA
Sbjct: 399 AKLRKVSRMEDTSFPSGGNAIGVNSASSKTDTGRGNGPLPLGGSGLMEEMSALLARRRRI 458
Query: 742 ASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAP 801
A S + +++KG+ + K T+ P G S S P+ P
Sbjct: 459 AEKGSTIETEQKEDKGEDSEPVTSKASSTSTPEPTRKPWERTNTMNGSKSPVISRPKSTP 518
Query: 802 PGQPQ----QGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQ 841
QP Q + + +K +L++ + ++ + E D RQ
Sbjct: 519 LSQPSANGVQTEGLDYDRLKQDILDEMRKELTKLKEELIDAIRQ 562
Score = 65.9 bits (159), Expect = 2e-10
Identities = 47/122 (38%), Positives = 64/122 (52%), Gaps = 25/122 (20%)
Query: 382 GGQYENFRVQYTETEPYHNYRERERER-ERENRQRER------ERER-ERDR------ER 427
G E +Q + + +E ERER ERE +RER ERER ER+R ER
Sbjct: 134 GPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLER 193
Query: 428 ERRQREREREREHERDKERQRR-----------KEEWERERAKRDEKDRQHRDRDREKER 476
ER++RER+ E + ERQ R +E ERER +R E++RQ R+R + ER
Sbjct: 194 ERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLER 253
Query: 477 EK 478
E+
Sbjct: 254 EQ 255
Score = 53.5 bits (127), Expect = 9e-07
Identities = 45/133 (33%), Positives = 60/133 (45%), Gaps = 15/133 (11%)
Query: 386 ENFRVQYTETEPYHNYRERERERERENR---QRERERERERDRER-ERRQRER----ERE 437
E R++ + E RER+ ER+ R Q ER+ DRER ER++RER ERE
Sbjct: 182 ERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERE 241
Query: 438 R-EHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSP--QPPSRQ 494
R E ER ++ +R + EWERER E G P Q S+
Sbjct: 242 RQERERQEQLEREQLEWERER----RISSAAAPASVETPLNSVLGDSSASEPGLQAASQP 297
Query: 495 AEPPKKEAATTGP 507
AE P ++ GP
Sbjct: 298 AETPSQQGIVLGP 310
Score = 36.2 bits (82), Expect = 0.15
Identities = 58/250 (23%), Positives = 88/250 (35%), Gaps = 25/250 (10%)
Query: 57 GPSQEE---EDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLR 113
GPSQEE + E+ R E + + + E E R E + E +R R
Sbjct: 134 GPSQEELEIQRRQLQEQQRQKELERERLERERMERER--------LERERLERERLERER 185
Query: 114 DEASSVTRELDEHE----LDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKA 169
E + RE E E L+ E + + QE + + E+ E RE +
Sbjct: 186 LEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQER 245
Query: 170 GVQSVGEKESLEAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDP---SDRKVRPRPTCRF 226
Q E+E LE +E++ + L + +P + + P+ +
Sbjct: 246 ERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQG 305
Query: 227 FMKGNCTWGMNCRFIHPGVNDKGNYSLITKADPFPPNGAPPLGPHPLMPANPWGGPVVDE 286
+ G P + + +L P PP P GP P P P V
Sbjct: 306 IVLGPLAPPPPPPL--PPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQV--- 360
Query: 287 ILPPPPPEPP 296
PPPPP PP
Sbjct: 361 --PPPPPPPP 368
Score = 32.0 bits (71), Expect = 2.8
Identities = 60/290 (20%), Positives = 108/290 (37%), Gaps = 33/290 (11%)
Query: 12 HSPEDEEQPQGLSDDDILRDSGSDQDLDG-AGVRASDLEDEESAARGPSQEEEDNH--SD 68
H D Q GL+ GS +D + A LE S GP+ +++ +
Sbjct: 78 HQWRDARQVYGLN-------FGSKEDANVFASAMMHALEVLNSQETGPTLPRQNSQLPAQ 130
Query: 69 EEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVTRELDEHEL 128
++ S+ + + Q ++ E R E E + E +R R E + RE E E
Sbjct: 131 VQNGPSQEELEIQRRQLQEQQRQK-----ELERERLERERMERERLERERLERERLERER 185
Query: 129 DYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESLEAAKEKKK 188
E++ E +++ E+ + +E+ E R + + Q E+E LE + +++
Sbjct: 186 LEQEQLERERQERERQERLERQERLERQERLERQERLDRER--QERQERERLERLERERQ 243
Query: 189 EDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKGNCTWGMNCRFIHPGVNDK 248
E + E LE +++ +R++ + +N ++
Sbjct: 244 ERERQE---------QLEREQLEWERERRISSAAA-----PASVETPLNSVLGDSSASEP 289
Query: 249 GNYSLITKADPFPPNGAP--PLGPHPLMPANPWGGPVVDEILPPPPPEPP 296
G + A+ G PL P P P P + PPP P PP
Sbjct: 290 GLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPP 339
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 92.8 bits (229), Expect = 1e-18
Identities = 195/886 (22%), Positives = 330/886 (37%), Gaps = 154/886 (17%)
Query: 83 SEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVTRELDEHELDYDEEVPEEPAPAV 142
SE N+ RG P E +R S L ++S +ELD+ + + D E E A A
Sbjct: 272 SETNKGLRGRGPPPSWAS----EPERPSIL---SASELKELDKFD-NLDAEADEGWAGAQ 323
Query: 143 QE-DEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESLEAAKEKKKEDDDGEIDDGEID 201
E D E+ DD+E+G +P+E + G K S E KKE D
Sbjct: 324 MEVDYTEQLNFSDDDEQGSNSPKENNS---EDQGSKASEN--NENKKETD---------- 368
Query: 202 DDDLEEGEVKDPSDRKVRPRPTCRFFMKG---NCTWGMNCRFIHPGVNDKGNYSLITKAD 258
E K S +P + KG N G + P L+ +
Sbjct: 369 ----EVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSSHLPPPP-------KLLAQQH 417
Query: 259 PFPPNGAPPLGPHPLMPANPWGGPVVDEILPPPPPEPPTESAWERGLRHAKEV---LKKA 315
P P A P P P P V DE + W++ R E+ +++A
Sbjct: 418 PPPDRQAVPGRPGPF----PSKQQVADE-----------DEIWKQRRRQQSEISAAVERA 462
Query: 316 TIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVRDTVLEPYADPYYDYE 375
R+E+E E++ E + D++ + S P ++R+
Sbjct: 463 RKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPS--PEEIRE-------------- 506
Query: 376 IERFWRGGQYENFRVQYTETEPYHNYRERERERERE-NRQRERERERERDRERERRQRER 434
R + E R + E E +E+ERE+ERE +R+R++E+E+E ++E+E +QRE
Sbjct: 507 -----REREKEREREKELEKE-----QEQEREKEREKDRERQQEKEKELEKEQE-KQREM 555
Query: 435 EREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSP------ 488
E+ER+ E++KE +R+KE+ E+E K E Q ++ + EKEREK + K +PR P
Sbjct: 556 EKERKQEKEKELERQKEK-EKELQKMKE---QEKECELEKEREKLEEKIEPREPNLEPMV 611
Query: 489 -QPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPK--------------KKLGVSV 533
+ S + ++E T R+++ P P+ K+ S+
Sbjct: 612 EKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSL 671
Query: 534 SPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSS-------------RSRSRSSSYS 580
P R++ + ++ S S+ + + +
Sbjct: 672 PPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASM 731
Query: 581 SYSSRSSRHSSFSGSRSRS-RSFSSSPSPSPTPSPHRPSI-RTKGEPAPPPGKAGE---K 635
+ R S+ R S R P P P +P + R + E +P ++ E +
Sbjct: 732 GFDPRWLMMQSYMDPRMMSGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNSSESFEHIAR 791
Query: 636 SVKKPAPPPAPPQATKTTAPVP--EPTKPGDPREARRKE---RPARTPPRRRTLSGSGSG 690
S + A + P+ + P P EP + P+ E A + T + S
Sbjct: 792 SARDHAISLSEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAALDQEQITAAYSVEH 851
Query: 691 SGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPA 750
+ + R S + V S + H D+ + A +P S
Sbjct: 852 NQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQEER 911
Query: 751 QTRKEKGKSKKED---GVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQ 807
+ E S+K G ++ + ++P SA P P + P +P++
Sbjct: 912 ISAVESQPSRKRSVSHGSNHTQKPDEQRSEP--SAGIPKVTSRCIDSKEPIERPEEKPKK 969
Query: 808 GTFVAHKE-IKLTLLNKAADK-------GSRKRYEPSDKDRQSPPPAKRP---NTSPDRG 856
F+ E K + K+ + S +R E +D+ + P K+P + +R
Sbjct: 970 EGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEERE 1029
Query: 857 SRDRKSGGRLGS------PKPERQRGQNSKAPAAPADRKRQLSPQS 896
R K G + KPE+ ++ P P + PQS
Sbjct: 1030 QRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQS 1075
Score = 48.5 bits (114), Expect = 3e-05
Identities = 176/895 (19%), Positives = 308/895 (34%), Gaps = 133/895 (14%)
Query: 14 PEDEEQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESAA--RGPSQEEED---NHSD 68
PED L + I + + A +A + + A + S+ ED +H+D
Sbjct: 829 PEDVRSEAALDQEQITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTD 888
Query: 69 EEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRD--EASSVTRELDEH 126
++++ ++ DQ T S +EE E + S R S+ T++ DE
Sbjct: 889 ANNQSACFEAPDQK----------TLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQ 938
Query: 127 ELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESLEAAKEK 186
+ +P+ + + D E +++ K EG R + V + +S +
Sbjct: 939 RSEPSAGIPKVTSRCI--DSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPR 996
Query: 187 KKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKGNCTWGMNCRFIHPGVN 246
+ E++D + G +K P R ++ R +G
Sbjct: 997 PSSNRREEVNDRPVR----RSGPIKKPVLRDMKEEREQRKEKEGEKA------------- 1039
Query: 247 DKGNYSLITKADPFPPNGAPPLGPHPLMPANPWGGPVVDEILPPP-PPE----PPTESAW 301
+K ++ K + PP P P PA P+ + +PPP PE P TE+A
Sbjct: 1040 EKVTEKVVVKPEKTEKKDLPPPPPPPQPPA-----PIQPQSVPPPIQPEAEKFPSTETAT 1094
Query: 302 --ERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPR-D 358
++ + ++ L+ + + + + T+ + E E + +D PR D
Sbjct: 1095 LAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEKVISKDLVIERPRPD 1154
Query: 359 VRDTVLEPYADP---YYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQR 415
R V + P Y+ ER W Q R + +YR R R R
Sbjct: 1155 SRPAVKKESTLPPRTYWKEARERDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGH 1214
Query: 416 ERERERERDRE-----------RERRQREREREREHERDKERQRRKEEWERERAKRDEKD 464
R+ + RD + R+R + E E ++R R+R + D
Sbjct: 1215 TRDYPQYRDNKPRAEHIPSGPLRQREESETRSESSDFEVVPKRR------RQRGSETDTD 1268
Query: 465 RQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADE--WKDPWRRS 522
+ + +K+ KGK R +P ++ +P K ++ R D + P+ R
Sbjct: 1269 SEIHESASDKD-SLSKGKLPKREERPENK--KPVKPHSSFKPDNHVRIDNRLLEKPYVRD 1325
Query: 523 KSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSY 582
K K G RR R G+ R R
Sbjct: 1326 -DDKAKPGFLPKGEPTRRGR------------------------GGTFRRGGRDP----- 1355
Query: 583 SSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAP 642
R SR S+ R ++ S P P P R + K K +K P
Sbjct: 1356 GGRPSRPSTLRRPAYRDNQWNPRQSEVPKPEDGEPPRRHEQFIPIAADKRPPKFERKFDP 1415
Query: 643 PPAPPQATKTTAPVPEPTKPGDPREARRKERPARTP-------PRRRTLSG--------S 687
P+ + T P P KP PR R +ER A + P T++
Sbjct: 1416 ARERPRRQRPTRP-PRQDKP--PRFRRLREREAASKSNEVVAVPTNGTVNNVAQEPVNTL 1472
Query: 688 GSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSP 747
G SG+ S+++ S + +S +S + D E ADL + +
Sbjct: 1473 GDISGNKTPDLSNQNSSDQANEEWETASESSDFNERRERD-EKKNADLNAQTVVKVGENV 1531
Query: 748 APAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQ 807
P + K + V + R+ ++ PPKS + +G ++ ++ P ++ P
Sbjct: 1532 LPPKREIAKRSFSSQRPVDRQNRRGNNG--PPKSGRNFSGPRNERRSGPPSKSGKRGPFD 1589
Query: 808 GTFVAHKEIKLTLLNKAADK-------GSRKRYEPSDKDRQSPPPA-KRPNTSPD 854
+ L + A + G + + + K R+ P P K+P D
Sbjct: 1590 DQPAGTTGVDLINGSSAHHQEGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVD 1644
Score = 48.5 bits (114), Expect = 3e-05
Identities = 88/412 (21%), Positives = 146/412 (35%), Gaps = 62/412 (15%)
Query: 543 KTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSS--SYSSYSSRSSRHSSFSGSRSRSR 600
K +A+ S +S+ R + +G +++S +S +S S +S S S
Sbjct: 1711 KKNANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPL 1770
Query: 601 SFSSSPSPSPTPSPH-----RPSIRTKGEPAP-----PPGKAGEKSVKKPAPPPAPP--- 647
+ +P P+ T +P P + + P P P + S PA A
Sbjct: 1771 PATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITS 1830
Query: 648 QATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSV 707
+ +AP P P A + + P L+ + + + + ++ S + V
Sbjct: 1831 SSAPASAPAPTPILASVSTPASVTILASASIP---ILASALASTSAPTPAPAASSPAAPV 1887
Query: 708 SSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKE 767
+ ++ ++ ++S + S A +PVS+ + PAPAQT+ + K +
Sbjct: 1888 ITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQTHKPVQNP---- 1943
Query: 768 EKRKRDSSTQPPKSAKPP-----------AGGKSSQQPSTP----------QQAPPG--- 803
+ SS QPP S + P A GKS Q P + + APP
Sbjct: 1944 LQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLN 2003
Query: 804 ---------QPQQGTFVAHKEIKLTLLNKA-----ADKGSRKRYEPSDKDRQSPPPAKRP 849
P Q V+ LT A A G E Q PA
Sbjct: 2004 DISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNG 2063
Query: 850 NTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSSK 901
N + KS ++ P+P+ QR + +A A + LSP K
Sbjct: 2064 NENEVVPVLSEKSADKI--PEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHK 2113
Score = 47.0 bits (110), Expect = 8e-05
Identities = 168/863 (19%), Positives = 273/863 (31%), Gaps = 129/863 (14%)
Query: 154 DDEEKGEGTP------REEGKAGVQSVGEKESLEAAKEKKKEDD-DGEIDDGEIDDDDLE 206
D++ + E P REE + +S + + +++ E D D EI + D D L
Sbjct: 1223 DNKPRAEHIPSGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESASDKDSLS 1282
Query: 207 EGEVKDPSDRKVRPRPTCRF--FMKGNCTWGMNCRFIHPGV--NDKGNYSLITKADP--- 259
+G++ +R +P F N N P V +DK + K +P
Sbjct: 1283 KGKLPKREERPENKKPVKPHSSFKPDNHVRIDNRLLEKPYVRDDDKAKPGFLPKGEPTRR 1342
Query: 260 -----FPPNGAPPLGPHPLMPA---------NPWGGPVVDEILPPPPPEPPTESAWERGL 305
F G P G P P+ N W P E+ P EPP
Sbjct: 1343 GRGGTFRRGGRDP-GGRPSRPSTLRRPAYRDNQWN-PRQSEVPKPEDGEPPR-------- 1392
Query: 306 RHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREF-------DKENEVFRDWNSRIPRD 358
RH + + I ++ P E++F R+ DK R
Sbjct: 1393 RHEQFI----PIAADKRPPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASK 1448
Query: 359 VRDTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERE 418
+ V P + E G + + + E E E+
Sbjct: 1449 SNEVVAVPTNGTVNNVAQEPVNTLGDISGNKTPDLSNQNSSDQANEEWETASESSDFNER 1508
Query: 419 RERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHR--DRDREKER 476
RER+ + + + + E+ +R+ K + +R DRQ+R + K
Sbjct: 1509 RERDEKKNADLNAQTVVKVGENVLPPKREIAKRSFSSQRPV----DRQNRRGNNGPPKSG 1564
Query: 477 EKEKGKPKPRSPQPPSRQAEP---PKKEAATTGPQV-----------------------K 510
G R PPS+ + + A TTG +
Sbjct: 1565 RNFSGPRNERRSGPPSKSGKRGPFDDQPAGTTGVDLINGSSAHHQEGVPNGTGQKNSKDS 1624
Query: 511 RADEWKDPWRRSKSPKKKLG-------------VSVSPSRARRRRKTSASSASASNSSRS 557
+ +DP K PK+K+ V + + S+ + +
Sbjct: 1625 TGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVIEDPQSNLNDDGFTEV 1684
Query: 558 SSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRP 617
S+ R + ++ +++ S + F+ + +
Sbjct: 1685 VSKKQQKRLQDEERRKKEEQVIQVWNKKNANEKGRSQTSKLPPRFAKKQATGIQQAQSSA 1744
Query: 618 SIRTKGEPAPPPGKAGEKSVKKPAPPPA--PPQATKTTAPVPEPTKPGDPREARRKERPA 675
S+ PP + AP PA P T+APVP T P A
Sbjct: 1745 SVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLA--PVLASTSAPVP 1802
Query: 676 RTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADL 735
+P + S S S +S S+S + S S+ +S + T +S + S + A
Sbjct: 1803 ASPLAPVSASASVS---ASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASA 1859
Query: 736 ASPV---SSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQ 792
+ P+ + AS+ +P PA S P SA PA +
Sbjct: 1860 SIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPA--PAPT 1917
Query: 793 QPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTS 852
S P APP P Q HK ++ L S +Q PP + P+
Sbjct: 1918 PVSAPNPAPPA-PAQTQAQTHKPVQNPL------------QTTSQSSKQPPPSIRLPSAQ 1964
Query: 853 PDRGSRDRKSGGRLGSPKPE----RQRGQNSKAPAAPA-DRKRQLSPQSKSSSKVTSVPG 907
G+ SG + +P+ + N AP A D ++L P S S
Sbjct: 1965 TPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWN 2024
Query: 908 K-----ASDPGAASTKSGKASTL 925
K S P + K+G+ S L
Sbjct: 2025 KPLTSFGSAPSSEGAKNGQESGL 2047
Score = 42.0 bits (97), Expect = 0.003
Identities = 41/183 (22%), Positives = 73/183 (39%), Gaps = 4/183 (2%)
Query: 12 HSPEDEEQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQEEEDNHSDEED 71
H P D + G + +D+D R E + R + EE+ EE
Sbjct: 417 HPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQ 476
Query: 72 R--ASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVTRELDEHELD 129
R A K + D ++ L + P+ E E E +R +L E + E + +
Sbjct: 477 RKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRE 536
Query: 130 YDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKES-LEAAKEKKK 188
+E E+ QE + E E++ E ++E + +Q + E+E E KE++K
Sbjct: 537 RQQE-KEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREK 595
Query: 189 EDD 191
++
Sbjct: 596 LEE 598
Score = 39.3 bits (90), Expect = 0.018
Identities = 172/954 (18%), Positives = 306/954 (32%), Gaps = 180/954 (18%)
Query: 44 RASDLEDEESAARGPSQEEEDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDE 103
R +LE E+ R +E++ E+++ E K Q++ E+ + + E + ++
Sbjct: 515 REKELEKEQEQEREKEREKDRERQQEKEKELE-KEQEKQREMEKERKQEKEKELERQKEK 573
Query: 104 GEEDRTSDLRDEASSVTRELDEHELDYDEEVPEEP--APAVQEDEAEKAGAEDDE----- 156
+E + +++ + +E ++ E ++ P EP P V++ E+E + +++E
Sbjct: 574 EKELQKMKEQEKECELEKEREKLE---EKIEPREPNLEPMVEKQESENSCNKEEEPVFTR 630
Query: 157 -----EKGEGTP---REEGKAGVQSVGE---------KESLEAAKEKKKEDDDGEIDDGE 199
+ E TP E ++G Q ++SL ++++E + +
Sbjct: 631 QDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ 690
Query: 200 IDDDDLEEGEVKDPSDRKVRPRPTCRFFM------KGNCTWGMNCRFIHPGVNDKGNYSL 253
L + PS V P P + + + G + R++ +
Sbjct: 691 QQQGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWL----------MM 740
Query: 254 ITKADPFPPNGAPPLGPHPLMPANPWGGPVVDEILPPPPPEPPTESAWERGLRHAKEVLK 313
+ DP +G P + P+ P G + PP+P G ++ E +
Sbjct: 741 QSYMDPRMMSGRPAMDIPPIHP-----GMI--------PPKPLMRRDQMEGSPNSSESFE 787
Query: 314 K-ATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVRDTVLEPYADPYY 372
A ++ E R + G D + + + P DVR
Sbjct: 788 HIARSARDHAISLSEPR--MLWGSDPYPHAEPQQATTPKATEEPEDVRSEAALDQEQITA 845
Query: 373 DYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERE---NRQRERERERERDRERER 429
Y +E E P ++ E + + +R E R D +
Sbjct: 846 AYSVEH------------NQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQS 893
Query: 430 RQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPR--- 486
E ++ +E + E + R + H + E+ E G PK
Sbjct: 894 ACFEAPDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRC 953
Query: 487 --SPQPPSRQAEPPKKEA---ATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRR 541
S +P R E PKKE ++ GP+ ++ + K R P V+ RR
Sbjct: 954 IDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRS 1013
Query: 542 RKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRS 601
R R + + + ++ +
Sbjct: 1014 GPIKKPVLRDMKEER----------------EQRKEKEGEKAEKVTEKVVVKPEKTEKKD 1057
Query: 602 FSSSPSPSPTPSPHRPS-----IRTKGEPAPPPGKA-----GEKSVKKPAPPPAPPQ--- 648
P P P+P +P I+ + E P A + +KP P + Q
Sbjct: 1058 LPPPPPPPQPPAPIQPQSVPPPIQPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEP 1117
Query: 649 ATKT------TAPVPEPTKP---------------GDPREARRKERPARTPPRR------ 681
A KT APV + K D R A +KE + PPR
Sbjct: 1118 AVKTVNQQTMAAPVVKEEKQPEKVISKDLVIERPRPDSRPAVKKE--STLPPRTYWKEAR 1175
Query: 682 -------RTLSGSGSGS----GSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSED 730
+ G G G G SY GS + A + S
Sbjct: 1176 ERDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKPRAEHIPSGP 1235
Query: 731 MYADLASPVSSASSRSPAPAQTRKEKGKSKKEDG-VKEEKRKRDSSTQPPKSAKPPAGGK 789
+ S S SS + R+++G D + E +DS ++ GK
Sbjct: 1236 LRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESASDKDSLSK----------GK 1285
Query: 790 SSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRP 849
++ P+ P +P +F +++ N+ +K P +D P P
Sbjct: 1286 LPKREERPENKKPVKP-HSSFKPDNHVRID--NRLLEK-------PYVRDDDKAKPGFLP 1335
Query: 850 NTSPDRGSRDR--KSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSSK 901
P R R + GGR +P R PA R Q +P+ K
Sbjct: 1336 KGEPTRRGRGGTFRRGGRDPGGRPSR-----PSTLRRPAYRDNQWNPRQSEVPK 1384
Score = 38.9 bits (89), Expect = 0.023
Identities = 93/490 (18%), Positives = 182/490 (37%), Gaps = 91/490 (18%)
Query: 431 QREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDR---------EKEREKEKG 481
+++++R ++ ER K+ ++ + W ++ A + + + R ++ +
Sbjct: 1687 KKQQKRLQDEERRKKEEQVIQVWNKKNANEKGRSQTSKLPPRFAKKQATGIQQAQSSASV 1746
Query: 482 KPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRR 541
P +P PPS A P +A + + + L + +P A
Sbjct: 1747 PPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPL 1806
Query: 542 RKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGS---RSR 598
SAS++ +++ S+S ++ S S + + + + +S S+ +S S S +
Sbjct: 1807 APVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILAS 1866
Query: 599 SRSFSSSPSPSPTPS---------------------PHRPSIRTKGEPAPPPGKAGEKSV 637
+ + +S+P+P+P S P P+ + PAP P A +
Sbjct: 1867 ALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAP 1926
Query: 638 KKPA--------PPPAPPQATKTTAPVPEP--------TKPGDPREARRKERPARTPPRR 681
PA P P Q T ++ P P T G A K +TP
Sbjct: 1927 PAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKS--IQTPQSH 1984
Query: 682 RTLSG----------SGSGSGSSYSGSSSRSRSLSVSS----VSSVSSATSSSSSAHSVD 727
TL+ + S G S + SVS+ ++S SA SS + + +
Sbjct: 1985 GTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQE 2044
Query: 728 SE-DMYAD---LASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAK 783
S ++ D +P S+ + P + K K + +E+R++ P K+ K
Sbjct: 2045 SGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPE----PKEQRQKQPRAGPIKAQK 2100
Query: 784 PPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSP 843
P P ++ PG + + ++++K ++ EP +++ P
Sbjct: 2101 LP-----DLSPVENKEHKPGPIGKERSLKNRKVK-----------DAQQVEPEGQEK--P 2142
Query: 844 PPAKRPNTSP 853
PA +T P
Sbjct: 2143 SPATVRSTDP 2152
Score = 37.7 bits (86), Expect = 0.051
Identities = 121/608 (19%), Positives = 184/608 (30%), Gaps = 118/608 (19%)
Query: 413 RQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDR 472
R RE DR RR ++ + +ER++RKE+ + K EK ++
Sbjct: 996 RPSSNRREEVNDRP-VRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTE 1054
Query: 473 EKEREKEKGKPKPRSP--------------------------QPPSRQAEPPKKEAATTG 506
+K+ P+P +P Q PS+ E P + +T
Sbjct: 1055 KKDLPPPPPPPQPPAPIQPQSVPPPIQPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQ 1114
Query: 507 --PQVKRADEWK---DPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASA---------- 551
P VK ++ + K P+K + + R R + + S
Sbjct: 1115 VEPAVKTVNQQTMAAPVVKEEKQPEKVISKDLVIERPRPDSRPAVKKESTLPPRTYWKEA 1174
Query: 552 -----------------SNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSG 594
SR S SY G G R + Y Y R
Sbjct: 1175 RERDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRG-GRGHTRDYPQYRDNKPRAEHIPS 1233
Query: 595 SRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTA 654
R R S + S S R +G + E + K + +
Sbjct: 1234 GPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESASDKDSLSKGKLPKREERP 1293
Query: 655 PVPEPTKPG-----------DPREARR-------KERPARTP---PRRRTLSGSGSGSGS 693
+P KP D R + K +P P P RR G+ G
Sbjct: 1294 ENKKPVKPHSSFKPDNHVRIDNRLLEKPYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGGR 1353
Query: 694 SYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTR 753
G SR +L + S D E P P A R
Sbjct: 1354 DPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPEDGE--------PPRRHEQFIPIAADKR 1405
Query: 754 KEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPP---------AGGKSSQQPSTPQQAPPGQ 804
K + K + E+ +R T+PP+ KPP A KS++ + P
Sbjct: 1406 PPKFERKFDPA--RERPRRQRPTRPPRQDKPPRFRRLREREAASKSNEVVAVPTNGTVNN 1463
Query: 805 PQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGG 864
Q +I NK D ++ SD+ + A + +R RD K
Sbjct: 1464 VAQEPVNTLGDIS---GNKTPDLSNQ---NSSDQANEEWETASESSDFNERRERDEKKNA 1517
Query: 865 RLGSP----------KPERQRGQNSKAPAAPADRK-RQLSPQSKSSSKVTSVPGKASDPG 913
L + P+R+ + S + P DR+ R+ + S + S P G
Sbjct: 1518 DLNAQTVVKVGENVLPPKREIAKRSFSSQRPVDRQNRRGNNGPPKSGRNFSGPRNERRSG 1577
Query: 914 AASTKSGK 921
S KSGK
Sbjct: 1578 PPS-KSGK 1584
Score = 37.4 bits (85), Expect = 0.067
Identities = 70/370 (18%), Positives = 130/370 (35%), Gaps = 43/370 (11%)
Query: 462 EKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAE-------PPKKEAATTGPQVKRADE 514
EK +E+ +++ + P P E P KE + +VK A +
Sbjct: 2074 EKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQ 2133
Query: 515 WKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRS 574
+ + SP +V + ++T A S ++ S SS+ G+ + S
Sbjct: 2134 VEPEGQEKPSP-----ATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNAKES-- 2186
Query: 575 RSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGE--PAPP---- 628
+ Y++ SS + + ++ ++ P P+ P P R +I+ PP
Sbjct: 2187 -VTDYTTPSSSLPNTVATNNTKMEDTLVNNVPLPNTLPLPKRETIQQSSSLTSVPPTTFS 2245
Query: 629 -------PGKAGEKSVK-----KPAPPPAPPQAT--KTTAPVPEPTKPGDPREARRKERP 674
KA E S P APP AT ++A P A + P
Sbjct: 2246 LTFKMESARKAWENSPNVREKGSPVTSTAPPIATGVSSSASGPSTANYNSFSSASMPQIP 2305
Query: 675 ARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYAD 734
+ +LSG+G +Y+ SS ++S + S ++ S+ S ++
Sbjct: 2306 VASVTPTASLSGAG-----TYTTSSLSTKSTTTSDPPNICKVKPQQLQTSSLPSASHFSQ 2360
Query: 735 LASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEK---RKRDSSTQPPKSAKPPAGGKSS 791
L+ S + + P + ++ + + + PP A+
Sbjct: 2361 LSCMPSLIAQQQQNPQVYVSQSAAAQIPAFYMDTSHLFNTQHARLAPPSLAQQQGFQPGL 2420
Query: 792 QQPSTPQQAP 801
QP++ QQ P
Sbjct: 2421 SQPTSVQQIP 2430
Score = 34.3 bits (77), Expect = 0.57
Identities = 46/201 (22%), Positives = 69/201 (34%), Gaps = 27/201 (13%)
Query: 627 PPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSG 686
P G G+ + P P Q T A ++P + R PA T +G
Sbjct: 2594 PNFGSTGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPAGTQHSMIATTG 2653
Query: 687 SGS-------GSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPV 739
S GSG + S + SS ATS+S ++ S +
Sbjct: 2654 KMSEMELKAFGSGIDIKPGTPPIAGRSTTPTSSPFRATSTSPNSQSSKMNSIVYQKQFQS 2713
Query: 740 SSASSRSPAPAQTR-------------------KEKGKSKKEDGVKEEKRKRDSSTQPPK 780
+ A+ R P T+ E+ +SK+ G K +K DSS +PP+
Sbjct: 2714 APATVRMTQPFPTQFAPQAKQRAEVLQSTQRFFSEQQQSKQIGGGKAQKVDSDSS-KPPE 2772
Query: 781 SAKPPAGGKSSQQPSTPQQAP 801
+ P G + P AP
Sbjct: 2773 TLTDPPGVCQEKVEEKPPPAP 2793
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 92.0 bits (227), Expect = 2e-18
Identities = 72/234 (30%), Positives = 117/234 (50%), Gaps = 30/234 (12%)
Query: 319 KEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVRDTVLEPYADPYYDYEIER 378
K+ + D ++ + E+E D++ + R+ + R+ E + D E E+
Sbjct: 70 KDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREK 129
Query: 379 FWRGGQYENFRVQYTETEPYHNYRERERERERENR-----QRERERERERDRERER---- 429
+G + E R + E + R+RE+ERER+ QRE E ERERDRERE+
Sbjct: 130 -QKGRERERDRGRERERD-----RDREKERERQTEKDRDGQRETETERERDREREKQKER 183
Query: 430 -------RQREREREREHERDKERQR-RKEEWERERAKRDEKDRQHRDRDREKEREKEKG 481
RQR+ E+ERE + D+ER R RK + ER+R + D + + DR RE++R++++G
Sbjct: 184 ETERDRDRQRDTEKERERQTDRERDRQRKTQTERQR-ETDREGERETDRRRERQRDRDRG 242
Query: 482 KPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSP 535
K + R + + KKE + K E K +R + K+K G +SP
Sbjct: 243 KERDRERDRKEERKKERKKE------RKKERKEKKKEEKRREDKKRKWGEGISP 290
Score = 87.8 bits (216), Expect = 4e-17
Identities = 51/176 (28%), Positives = 88/176 (50%), Gaps = 5/176 (2%)
Query: 402 RERERERERENRQRERERERERDRERERRQRE--REREREHERDKERQRRKEEWERERAK 459
R+RER+R RE ++ER+R+R+RDRER R+++E R R+RE + + ER R +E+ + +
Sbjct: 77 RQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERE 136
Query: 460 RDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPW 519
RD + RDRDREKERE++ K + + + + ++E + D +D
Sbjct: 137 RDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTE 196
Query: 520 RRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSR 575
+ + + ++ R+R+T ++ R R G R R R
Sbjct: 197 KERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRD---RGKERDRER 249
Score = 84.3 bits (207), Expect = 5e-16
Identities = 47/161 (29%), Positives = 87/161 (54%), Gaps = 3/161 (1%)
Query: 402 RERERERERENRQRERERERERDRERERR-QREREREREHERDKERQRRKEEWERERAKR 460
R+R+R+R+RE R++E+E R RDRE++ +R+RERE++ R++ER R +E ER+R +
Sbjct: 92 RDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRER-ERDRDRE 150
Query: 461 DEKDRQ-HRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPW 519
E++RQ +DRD ++E E E+ + + R Q ++ T + ++ D +D
Sbjct: 151 KERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQ 210
Query: 520 RRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSR 560
R++++ +++ RRR+ R R
Sbjct: 211 RKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDR 251
Score = 80.5 bits (197), Expect = 7e-15
Identities = 52/163 (31%), Positives = 85/163 (52%), Gaps = 6/163 (3%)
Query: 403 ERERERERENRQRERERERERDRERER-RQREREREREHERDKERQRRKE-EWERERAKR 460
E ER+RERE +Q+ RERER+R RERER R RE+ERER+ E+D++ QR E E ER+R +
Sbjct: 120 EIERDRERE-KQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRERE 178
Query: 461 DEKDRQ---HRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKD 517
+K+R+ RDR R+ E+E+E+ + R Q ++ + + +R + +D
Sbjct: 179 KQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRD 238
Query: 518 PWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSR 560
R + +++ ++ RK R +
Sbjct: 239 RDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKK 281
Score = 78.2 bits (191), Expect = 3e-14
Identities = 53/152 (34%), Positives = 84/152 (55%), Gaps = 17/152 (11%)
Query: 402 RERERERERE---NRQRERE--RERERDRERER---RQREREREREHERDKERQRRKE-E 452
R R+RE++ E +R+RE++ RERERDR RER R RE+ERER+ E+D++ QR E E
Sbjct: 111 RNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETE 170
Query: 453 WERERAKRDEKDRQ-HRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKR 511
ER+R + +K+R+ RDRDR+++ EKE+ + R+ + +K + R
Sbjct: 171 RERDREREKQKERETERDRDRQRDTEKER-------ERQTDRERDRQRKTQTERQRETDR 223
Query: 512 ADEWKDPWRRSKSPKKKLGVSVSPSRARRRRK 543
E + RR + + G R R+ +
Sbjct: 224 EGERETDRRRERQRDRDRGKERDRERDRKEER 255
Score = 75.9 bits (185), Expect = 2e-13
Identities = 60/167 (35%), Positives = 92/167 (55%), Gaps = 19/167 (11%)
Query: 302 ERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRD-VR 360
ER +E + KE+E E+ R E ERE D+E E ++ + RD R
Sbjct: 134 ERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQR 193
Query: 361 DTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERE-NRQRERER 419
DT E ER R E R + T+TE RE +RE ERE +R+RER+R
Sbjct: 194 DT------------EKER-ERQTDRERDRQRKTQTE---RQRETDREGERETDRRRERQR 237
Query: 420 ERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQ 466
+R+R +ER+ R+R+R+ ER+ ER KER++ ++E ++E +R++K R+
Sbjct: 238 DRDRGKERD-RERDRKEERKKERKKERKKERKEKKKEEKRREDKKRK 283
Score = 47.8 bits (112), Expect = 5e-05
Identities = 47/164 (28%), Positives = 68/164 (41%), Gaps = 60/164 (36%)
Query: 298 ESAWERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPR 357
E ER ++ + +E++ D E R T E +RE D+E E
Sbjct: 178 EKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGE----------- 226
Query: 358 DVRDTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRER 417
ET+ R RER QR+R
Sbjct: 227 -----------------------------------RETD-----RRRER-------QRDR 239
Query: 418 ERERERDRERERRQREREREREHERDKER-QRRKEEWERERAKR 460
+R +ERDRER+R++ ER++ER+ ER KER +++KEE RE KR
Sbjct: 240 DRGKERDRERDRKE-ERKKERKKERKKERKEKKKEEKRREDKKR 282
Score = 47.4 bits (111), Expect = 6e-05
Identities = 46/207 (22%), Positives = 76/207 (36%), Gaps = 8/207 (3%)
Query: 8 ERDPHSPEDEEQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQEEEDNHS 67
ERD D E+ + + + RD +++ R E RG +E + +
Sbjct: 91 ERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDRE 150
Query: 68 DEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVT-RELDEH 126
E +R +E Q E R +E E + DR D E T RE D
Sbjct: 151 KERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQ 210
Query: 127 ELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESLEAAKEK 186
E E +E + + + D ++G+ RE + E+ E KE+
Sbjct: 211 RKTQTERQRETDREGERETDRRRE-RQRDRDRGKERDRERDRK------EERKKERKKER 263
Query: 187 KKEDDDGEIDDGEIDDDDLEEGEVKDP 213
KKE + + ++ +D + GE P
Sbjct: 264 KKERKEKKKEEKRREDKKRKWGEGISP 290
Score = 35.8 bits (81), Expect = 0.20
Identities = 27/141 (19%), Positives = 60/141 (42%), Gaps = 2/141 (1%)
Query: 79 QDQDSEVNELSRGPTSSPCEEEGD-EGEEDRTSDLRDEASSVTRELDEH-ELDYDEEVPE 136
+D D + + R E+E D + + DR +++ ++ R+ ++ E++ D E +
Sbjct: 70 KDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREK 129
Query: 137 EPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESLEAAKEKKKEDDDGEID 196
+ + D + + D EK E+ + G + + + +EK+KE +
Sbjct: 130 QKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDR 189
Query: 197 DGEIDDDDLEEGEVKDPSDRK 217
D + D + E + DR+
Sbjct: 190 DRQRDTEKERERQTDRERDRQ 210
Score = 34.3 bits (77), Expect = 0.57
Identities = 37/182 (20%), Positives = 70/182 (38%), Gaps = 18/182 (9%)
Query: 420 ERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDR-EKEREK 478
+ +D + + RQRER+R RE K E ER+R ++ + R+R R EKE +
Sbjct: 67 QAHKDADGDDRQRERDRVRE----------KTEKERDRDRK-----RDRERRRKEKETNR 111
Query: 479 EKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRA 538
+ + K + + + +E + + D ++ R ++ K + G + +
Sbjct: 112 NRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETER 171
Query: 539 RRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSR 598
R R+ + R R + + R R + + R R + G R
Sbjct: 172 ERDREREKQKERETERDRDRQRDTEKERERQT-DRERDRQRKTQTER-QRETDREGERET 229
Query: 599 SR 600
R
Sbjct: 230 DR 231
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 90.1 bits (222), Expect = 9e-18
Identities = 76/207 (36%), Positives = 113/207 (54%), Gaps = 33/207 (15%)
Query: 303 RGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREF--DKENEVFRDWNSRIPRDVR 360
RG R A ++++ ++E+E + KR E +RE D++ + RD + RD R
Sbjct: 48 RGSRVAPAIIRERERQRERER--QRKRAKERHREKDREIEKDRDRQRKRDRERQRWRD-R 104
Query: 361 DTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERE---NRQRER 417
D E + D + E ER Q E R + + E ++RER+R+RE ++ RE
Sbjct: 105 DRKRERWGDRDRETETER-----QEERERQRDRKRE-----KDRERQRQREIGIDKDREI 154
Query: 418 ERERERDRERER------RQREREREREHE----RDKERQRRKEEWERER--AKRDEKDR 465
E E++RDRERE R RERER+++ E RD+ERQR KE+ ER+R K EKDR
Sbjct: 155 ETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDR 214
Query: 466 ---QHRDRDREKEREKEKGKPKPRSPQ 489
+ RDR+KER++E+ + K R Q
Sbjct: 215 YRERETGRDRDKERDRERQREKDRDRQ 241
Score = 79.7 bits (195), Expect = 1e-14
Identities = 54/152 (35%), Positives = 84/152 (55%), Gaps = 25/152 (16%)
Query: 402 REREREREREN-RQRERERERERDRERER---RQREREREREHERDKERQR--------- 448
RERER+RERE R+R +ER RE+DRE E+ RQR+R+RER+ RD++R+R
Sbjct: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
Query: 449 ----RKEEWERERAKRDEKDRQHR-------DRDREKEREKEKGKPKPRSPQPPSRQAEP 497
R+EE ER+R ++ EKDR+ + D+DRE E EK++ + + R E
Sbjct: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRER 177
Query: 498 PK-KEAATTGPQVKRADEWKDPWRRSKSPKKK 528
+ K+ T + + K+ R + +K+
Sbjct: 178 ERQKQRETRRDRDRERQREKEDRERDRDRQKE 209
Score = 78.6 bits (192), Expect = 3e-14
Identities = 53/144 (36%), Positives = 85/144 (59%), Gaps = 15/144 (10%)
Query: 402 RERERERER-ENRQRERERERERDRERERRQR---EREREREHERDKERQRRKEEWERER 457
R+RE E ER E R+R+R+R+RE+DRER+R++ +++RE E E+D++R+R E ER R
Sbjct: 114 RDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYR 173
Query: 458 AKRDEKDRQ---HRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADE 514
+ E+ +Q RDRDRE++REKE + + R Q ++ E + TG + D+
Sbjct: 174 DRERERQKQRETRRDRDRERQREKE-DRERDRDRQ---KEREKDRYRERETG---RDRDK 226
Query: 515 WKDPWR-RSKSPKKKLGVSVSPSR 537
+D R R K ++ + P R
Sbjct: 227 ERDRERQREKDRDRQKAIDCVPGR 250
Score = 76.3 bits (186), Expect = 1e-13
Identities = 46/133 (34%), Positives = 77/133 (57%), Gaps = 20/133 (15%)
Query: 402 REREREREREN---RQRERERERERDRERE-----RRQREREREREHERDKERQRRKE-- 451
R+R+R+R+RE R R+R+RER DR+RE + +RER+R+R+ E+D+ERQR++E
Sbjct: 88 RDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIG 147
Query: 452 -------EWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAAT 504
E E++R + E R RDRE+ER+K++ + R + RQ E +E
Sbjct: 148 IDKDREIETEKDRDREREMGETERYRDRERERQKQR---ETRRDRDRERQREKEDRERDR 204
Query: 505 TGPQVKRADEWKD 517
+ + D +++
Sbjct: 205 DRQKEREKDRYRE 217
Score = 56.6 bits (135), Expect = 1e-07
Identities = 43/133 (32%), Positives = 75/133 (56%), Gaps = 15/133 (11%)
Query: 318 RKEQEPDFEEKRFTVTIGEDEREF--DKENEVFRDWNSRIPRDVRDTVLEPYADPYYDYE 375
++E+E + KR + +RE DK+ E+ + + R++ +T + Y D E
Sbjct: 123 QEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGET------ERYRDRE 176
Query: 376 IERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERERRQRERE 435
ER Q E R + E + RER+R+R++E R+++R RERE R+R+ +ER+
Sbjct: 177 RER---QKQRETRRDRDRERQREKEDRERDRDRQKE-REKDRYRERETGRDRD---KERD 229
Query: 436 REREHERDKERQR 448
RER+ E+D++RQ+
Sbjct: 230 RERQREKDRDRQK 242
Score = 54.7 bits (130), Expect = 4e-07
Identities = 43/136 (31%), Positives = 70/136 (51%), Gaps = 21/136 (15%)
Query: 326 EEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDV---RDTVLEPYADPYYDYEIERFWRG 382
+ R T T ++ERE ++ + +D + R++ +D +E D + E+ R
Sbjct: 113 DRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERY 172
Query: 383 GQYENFRVQYTETEPYHNYRERERERERENRQRERER--ERERDRERER----------- 429
E R + ET R+RER+RE+E+R+R+R+R ERE+DR RER
Sbjct: 173 RDRERERQKQRETR---RDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERD 229
Query: 430 --RQREREREREHERD 443
RQRE++R+R+ D
Sbjct: 230 RERQREKDRDRQKAID 245
Score = 33.9 bits (76), Expect = 0.74
Identities = 42/184 (22%), Positives = 68/184 (36%), Gaps = 25/184 (13%)
Query: 8 ERDPHSPEDEEQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQEEEDNHS 67
+RD D E+ Q D D R+ D+D R ++ E +E R Q +
Sbjct: 87 DRDRQRKRDRER-QRWRDRDRKRERWGDRD------RETETERQEERER---QRDRKREK 136
Query: 68 DEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVTRELDEHE 127
D E + D+D E+ T + E + GE +R D E ++ E
Sbjct: 137 DRERQRQREIGIDKDREIE------TEKDRDREREMGETERYRDRERER----QKQRETR 186
Query: 128 LDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESLEAAKEKK 187
D D E E +ED + + EK RE G+ + + E ++++
Sbjct: 187 RDRDRERQRE-----KEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQ 241
Query: 188 KEDD 191
K D
Sbjct: 242 KAID 245
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 87.8 bits (216), Expect = 4e-17
Identities = 51/174 (29%), Positives = 92/174 (52%), Gaps = 9/174 (5%)
Query: 394 ETEPYHNYRERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEW 453
E E RE+ER+RER +++++ ++RER +ERER+++ERE++R+ R+KER++RK
Sbjct: 42 EREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRK--- 98
Query: 454 ERERAKRDEKDRQHRDRDREKE---REKE--KGKPKPRSPQPPSRQAEPPKKEAATTGPQ 508
+E+ KR+ K R R+R ++KE RE+E + + + R + ++ + K+E +
Sbjct: 99 -KEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRE 157
Query: 509 VKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSS 562
KR K+ + + +K + RR RK R R +
Sbjct: 158 RKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKT 211
Score = 85.5 bits (210), Expect = 2e-16
Identities = 51/162 (31%), Positives = 91/162 (56%), Gaps = 13/162 (8%)
Query: 402 RERERERERENRQRERERERERDRERERRQRERE---REREHERDKERQRRKEEWERERA 458
++RER +ERE +++ERE++R+ RE+ERR+R++E RER+ +ER+++KE ERER
Sbjct: 67 KKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERE 126
Query: 459 KRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDP 518
+ ++R+ + R R+K+R KE+ + K R + R+ + KKE + R + K+
Sbjct: 127 NKQRRERKRKKR-RKKKRRKERKREKERGKR--ERKRKKRKKEEREKKRERNRKERKKER 183
Query: 519 WRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSR 560
R+ + +KK R + RRK ++ S+
Sbjct: 184 ERKERRERKK-------ERKKERRKKKERKKDRKTDRQTDSQ 218
Score = 85.1 bits (209), Expect = 3e-16
Identities = 54/202 (26%), Positives = 97/202 (48%), Gaps = 3/202 (1%)
Query: 393 TETEPYHNYRERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEE 452
T+ E RERE+ + R++ER+RER + +++R++RER +ERE +R + ++RKE
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
Query: 453 WERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRA 512
E+ER KR +K+++ R+R + RE++K K + + ++ E +K+ + +R
Sbjct: 90 REKERRKR-KKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
Query: 513 DEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSS-YSGSGSSR 571
E K+ +R + KK+ R R R++ R R +
Sbjct: 149 RE-KERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKK 207
Query: 572 SRSRSSSYSSYSSRSSRHSSFS 593
R S R R S+F+
Sbjct: 208 DRKTDRQTDSQVFRPLRESAFN 229
Score = 50.4 bits (119), Expect = 8e-06
Identities = 35/150 (23%), Positives = 62/150 (41%), Gaps = 9/150 (6%)
Query: 454 ERERAKRDEKDRQHRDRDREKEREKEKGK--PKPRSPQPPSRQAEPPKKEAATTGPQVKR 511
E ER K++ ++R+ R R+REKER++E+GK K R + ++ E +KE + K+
Sbjct: 33 ESER-KKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKE------REKQ 85
Query: 512 ADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSR 571
E ++ RR + +KK R R++K N R + +
Sbjct: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145
Query: 572 SRSRSSSYSSYSSRSSRHSSFSGSRSRSRS 601
R R + + + R R+
Sbjct: 146 ERKREKERGKRERKRKKRKKEEREKKRERN 175
Score = 45.4 bits (106), Expect = 2e-04
Identities = 42/146 (28%), Positives = 72/146 (49%), Gaps = 8/146 (5%)
Query: 306 RHAKEVLKKATIRKEQE----PDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVRD 361
R KE K+ R+E+E ++KR G ER+ KE + N + R
Sbjct: 77 RKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRK 136
Query: 362 TVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERER 421
+ E ER R + + + + E + N +ER++ERER+ R RER++
Sbjct: 137 KRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKER---RERKK 193
Query: 422 ERDRERERRQREREREREHERDKERQ 447
ER +ER R+++ER+++R+ +R + Q
Sbjct: 194 ERKKER-RKKKERKKDRKTDRQTDSQ 218
Score = 42.4 bits (98), Expect = 0.002
Identities = 34/139 (24%), Positives = 59/139 (42%), Gaps = 10/139 (7%)
Query: 753 RKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVA 812
+KEK K KK + KE +RKR + K + K ++ ++ G+
Sbjct: 60 KKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGR-------- 111
Query: 813 HKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPE 872
+E K K ++ +++R E K R+ K +RG R+RK R + E
Sbjct: 112 -RERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEER-E 169
Query: 873 RQRGQNSKAPAAPADRKRQ 891
++R +N K +RK +
Sbjct: 170 KKRERNRKERKKERERKER 188
Score = 30.8 bits (68), Expect = 6.3
Identities = 15/42 (35%), Positives = 28/42 (66%), Gaps = 1/42 (2%)
Query: 402 RERERERERENRQR-ERERERERDRERERRQREREREREHER 442
RER++ER++E R++ ER+++R+ DR+ + + RE R
Sbjct: 189 RERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNR 230
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 87.4 bits (215), Expect = 6e-17
Identities = 106/447 (23%), Positives = 180/447 (40%), Gaps = 50/447 (11%)
Query: 250 NYSLITK--ADPFPPNGAPPLGPHPLMPANPWGGPVVDEILPPPPPEPPTESAWERGLRH 307
N +L++K +P P + L P GG ++ +PPPP E +S + +
Sbjct: 1671 NNNLVSKDTEEPLPVKESDQTLAALLSPKESSGG---EKEVPPPPKETLPDSGFSANI-- 1725
Query: 308 AKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVRDTVLEPY 367
E + +A + + P E+ ++ G + + R S + + + E
Sbjct: 1726 --EDINEADLVRPLLPKDMERLTSLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESS 1783
Query: 368 ADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRER 427
++ DYEI + + + +++ N + E+E++R++ R R + + +
Sbjct: 1784 SEEKDDYEI--------FVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHK 1835
Query: 428 ERRQREREREREHERD-KERQRRKEEWERERAKRDEKDRQHRDRDREKE---REKEKGKP 483
R++ R R +R K + R + R R++R + + R + R + +EK K P
Sbjct: 1836 SRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSP 1895
Query: 484 KPRSPQPPSRQAEPPKKE------AATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSR 537
K RS ++ ++ A + P + RRS+S ++ S+SPSR
Sbjct: 1896 KHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSR 1955
Query: 538 ARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRS 597
R R S S + S SR+ SR SR+ SR S S SR+ S S
Sbjct: 1956 --RSRTPSRRSRTPSRRSRTPSR--------RSRTPSRRSRTPSRRSRTPSRRRRSRSVV 2005
Query: 598 RSRSFSSSP---SPSPTPSPHRPS---IRTKGEPAPPPGKAGEK-------SVKKPAPPP 644
R RSFS SP S TP R S IR K + G++ ++ + + A
Sbjct: 2006 RRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDLDKAQLLEIAKAN 2065
Query: 645 APPQATKTTAPVPEPTKPGDPREARRK 671
A K P+P KP P K
Sbjct: 2066 AAAMCAKAGVPLPPNLKPAPPPTIEEK 2092
Score = 53.5 bits (127), Expect = 9e-07
Identities = 76/299 (25%), Positives = 112/299 (37%), Gaps = 39/299 (13%)
Query: 478 KEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSR 537
+++ P P R +E +E VK KD +SK K + +
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKV----KDTHEKSKKNKNR-------DK 1811
Query: 538 ARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRS 597
+ +K +S S S S+SS S S SRSR+R S S+S H S + SRS
Sbjct: 1812 GEKEKKRDSSLRSRSKRSKSSEHKSRKRTS-ESRSRARKRS-----SKSKSHRSQTRSRS 1865
Query: 598 RSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVP 657
RSR R S R++ + G +SV K +P +K+
Sbjct: 1866 RSRR-------------RRRSSRSRSK------SRGRRSVSKEKRKRSPKHRSKSR---E 1903
Query: 658 EPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSAT 717
K R+ R+ R P RR+ S + S S S RS S+S S S S
Sbjct: 1904 RKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRR 1963
Query: 718 SSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSST 776
S + S S + + S RS P++ R+ + ++ R R S T
Sbjct: 1964 SRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRT 2022
Score = 47.4 bits (111), Expect = 6e-05
Identities = 79/362 (21%), Positives = 123/362 (33%), Gaps = 59/362 (16%)
Query: 581 SYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPS-----PHRPSIRTKGEPAPPPGKAGEK 635
S +++ + H + S + P P P ++ +K P P K ++
Sbjct: 1631 SLTTQDTEHDMVISTSPSGGSEADIEGPLPAKDIHLDLPSNNNLVSKDTEEPLPVKESDQ 1690
Query: 636 SVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKE-------RPARTPPRRRTLSGSG 688
++ P K P P+ T P A ++ RP R S
Sbjct: 1691 TLAALLSPKESSGGEKEVPPPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRA 1750
Query: 689 SGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPA 748
G + R RS + VSS+ S SSS D E
Sbjct: 1751 GIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIF----------------V 1794
Query: 749 PAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQG 808
+ EK K K E+++KRDSS + KSS+
Sbjct: 1795 KVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRS-----KSSE---------------- 1833
Query: 809 TFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDR-KSGGRLG 867
HK K T +++ +RKR S K +S ++ + R SR R KS GR
Sbjct: 1834 ----HKSRKRTSESRSR---ARKRSSKS-KSHRSQTRSRSRSRRRRRSSRSRSKSRGRRS 1885
Query: 868 SPKPERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTS-VPGKASDPGAASTKSGKASTLS 926
K +R+R ++ + RKR S ++ + + S P + S S + S
Sbjct: 1886 VSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGR 1945
Query: 927 RR 928
RR
Sbjct: 1946 RR 1947
Score = 44.3 bits (103), Expect = 6e-04
Identities = 76/297 (25%), Positives = 115/297 (38%), Gaps = 34/297 (11%)
Query: 658 EPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVS-SVSSA 716
E +K R+ KE+ + R R+ S S S SRSR+ SS S S S
Sbjct: 1801 EKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQ 1860
Query: 717 TSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSST 776
T S S + S S + SR K K K +E KRKR SS
Sbjct: 1861 TRSRSRSRR--------RRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSR 1912
Query: 777 QPPKSAKPPAGGKSSQQPSTPQQA-PPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEP 835
K+ + S+ PS ++ P + ++ V + ++ + SR+ P
Sbjct: 1913 DNRKTVRA-----RSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTP 1967
Query: 836 SDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNS-----KAPAAPADRKR 890
S R+S P++R T P R SR R P R+R S +P +R
Sbjct: 1968 S---RRSRTPSRRSRT-PSRRSRTPSRRSR----TPSRRRRSRSVVRRRSFSISPVRLRR 2019
Query: 891 QLSPQSK--SSSKVTSVPGKASDPGAASTKSGKASTLSRREELLKQLKAVEDAIARK 945
+P + S S + ++S+ G +S K T + +LL+ KA A+ K
Sbjct: 2020 SRTPLRRRFSRSPIRRKRSRSSERG----RSPKRLTDLDKAQLLEIAKANAAAMCAK 2072
Score = 43.9 bits (102), Expect = 7e-04
Identities = 55/220 (25%), Positives = 91/220 (41%), Gaps = 18/220 (8%)
Query: 545 SASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSR----SR 600
S S A S S S S S+ RS SSYS+ + S SS++ RS +
Sbjct: 1073 SMMSPMADRSMMSMGADRSMMSSYSAADRSMMSSYSA--ADRSMMSSYTADRSMMSMAAD 1130
Query: 601 SFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQA----TKTTAPV 656
S++ S + + T + P + + P PP E + P PP PP+ T+ +A
Sbjct: 1131 SYTDSYTDTYTEAYMVPPLPPEEPPTMPPLPPEEPPMTPPLPPEEPPEGPALPTEQSALT 1190
Query: 657 PEPTKPGDPREARRKERPAR-TPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSV-- 713
E T P + + +E ++ PP ++ S + YS S+S L + +V
Sbjct: 1191 AENTWPTEVPSSPSEESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPE 1250
Query: 714 -----SSATSSSSSAHSVDSEDMYADLASPVSSASSRSPA 748
S+ + + +V +E+ PV+ S +PA
Sbjct: 1251 PPPEPESSITLTPVESAVVAEEHEVVPERPVTCMVSETPA 1290
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 87.4 bits (215), Expect = 6e-17
Identities = 106/447 (23%), Positives = 180/447 (40%), Gaps = 50/447 (11%)
Query: 250 NYSLITK--ADPFPPNGAPPLGPHPLMPANPWGGPVVDEILPPPPPEPPTESAWERGLRH 307
N +L++K +P P + L P GG ++ +PPPP E +S + +
Sbjct: 1671 NNNLVSKDTEEPLPVKESDQTLAALLSPKESSGG---EKEVPPPPKETLPDSGFSANI-- 1725
Query: 308 AKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVRDTVLEPY 367
E + +A + + P E+ ++ G + + R S + + + E
Sbjct: 1726 --EDINEADLVRPLLPKDMERLTSLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESS 1783
Query: 368 ADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRER 427
++ DYEI + + + +++ N + E+E++R++ R R + + +
Sbjct: 1784 SEEKDDYEI--------FVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHK 1835
Query: 428 ERRQREREREREHERD-KERQRRKEEWERERAKRDEKDRQHRDRDREKE---REKEKGKP 483
R++ R R +R K + R + R R++R + + R + R + +EK K P
Sbjct: 1836 SRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSP 1895
Query: 484 KPRSPQPPSRQAEPPKKE------AATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSR 537
K RS ++ ++ A + P + RRS+S ++ S+SPSR
Sbjct: 1896 KHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSR 1955
Query: 538 ARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRS 597
R R S S + S SR+ SR SR+ SR S S SR+ S S
Sbjct: 1956 --RSRTPSRRSRTPSRRSRTPSR--------RSRTPSRRSRTPSRRSRTPSRRRRSRSVV 2005
Query: 598 RSRSFSSSP---SPSPTPSPHRPS---IRTKGEPAPPPGKAGEK-------SVKKPAPPP 644
R RSFS SP S TP R S IR K + G++ ++ + + A
Sbjct: 2006 RRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDLDKAQLLEIAKAN 2065
Query: 645 APPQATKTTAPVPEPTKPGDPREARRK 671
A K P+P KP P K
Sbjct: 2066 AAAMCAKAGVPLPPNLKPAPPPTIEEK 2092
Score = 53.5 bits (127), Expect = 9e-07
Identities = 76/299 (25%), Positives = 112/299 (37%), Gaps = 39/299 (13%)
Query: 478 KEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSR 537
+++ P P R +E +E VK KD +SK K + +
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKV----KDTHEKSKKNKNR-------DK 1811
Query: 538 ARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRS 597
+ +K +S S S S+SS S S SRSR+R S S+S H S + SRS
Sbjct: 1812 GEKEKKRDSSLRSRSKRSKSSEHKSRKRTS-ESRSRARKRS-----SKSKSHRSQTRSRS 1865
Query: 598 RSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVP 657
RSR R S R++ + G +SV K +P +K+
Sbjct: 1866 RSRR-------------RRRSSRSRSK------SRGRRSVSKEKRKRSPKHRSKSR---E 1903
Query: 658 EPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSAT 717
K R+ R+ R P RR+ S + S S S RS S+S S S S
Sbjct: 1904 RKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRR 1963
Query: 718 SSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSST 776
S + S S + + S RS P++ R+ + ++ R R S T
Sbjct: 1964 SRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRT 2022
Score = 47.4 bits (111), Expect = 6e-05
Identities = 79/362 (21%), Positives = 123/362 (33%), Gaps = 59/362 (16%)
Query: 581 SYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPS-----PHRPSIRTKGEPAPPPGKAGEK 635
S +++ + H + S + P P P ++ +K P P K ++
Sbjct: 1631 SLTTQDTEHDMVISTSPSGGSEADIEGPLPAKDIHLDLPSNNNLVSKDTEEPLPVKESDQ 1690
Query: 636 SVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKE-------RPARTPPRRRTLSGSG 688
++ P K P P+ T P A ++ RP R S
Sbjct: 1691 TLAALLSPKESSGGEKEVPPPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRA 1750
Query: 689 SGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPA 748
G + R RS + VSS+ S SSS D E
Sbjct: 1751 GIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIF----------------V 1794
Query: 749 PAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQG 808
+ EK K K E+++KRDSS + KSS+
Sbjct: 1795 KVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRS-----KSSE---------------- 1833
Query: 809 TFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDR-KSGGRLG 867
HK K T +++ +RKR S K +S ++ + R SR R KS GR
Sbjct: 1834 ----HKSRKRTSESRSR---ARKRSSKS-KSHRSQTRSRSRSRRRRRSSRSRSKSRGRRS 1885
Query: 868 SPKPERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTS-VPGKASDPGAASTKSGKASTLS 926
K +R+R ++ + RKR S ++ + + S P + S S + S
Sbjct: 1886 VSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGR 1945
Query: 927 RR 928
RR
Sbjct: 1946 RR 1947
Score = 44.3 bits (103), Expect = 6e-04
Identities = 76/297 (25%), Positives = 115/297 (38%), Gaps = 34/297 (11%)
Query: 658 EPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVS-SVSSA 716
E +K R+ KE+ + R R+ S S S SRSR+ SS S S S
Sbjct: 1801 EKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQ 1860
Query: 717 TSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSST 776
T S S + S S + SR K K K +E KRKR SS
Sbjct: 1861 TRSRSRSRR--------RRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSR 1912
Query: 777 QPPKSAKPPAGGKSSQQPSTPQQA-PPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEP 835
K+ + S+ PS ++ P + ++ V + ++ + SR+ P
Sbjct: 1913 DNRKTVRA-----RSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTP 1967
Query: 836 SDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNS-----KAPAAPADRKR 890
S R+S P++R T P R SR R P R+R S +P +R
Sbjct: 1968 S---RRSRTPSRRSRT-PSRRSRTPSRRSR----TPSRRRRSRSVVRRRSFSISPVRLRR 2019
Query: 891 QLSPQSK--SSSKVTSVPGKASDPGAASTKSGKASTLSRREELLKQLKAVEDAIARK 945
+P + S S + ++S+ G +S K T + +LL+ KA A+ K
Sbjct: 2020 SRTPLRRRFSRSPIRRKRSRSSERG----RSPKRLTDLDKAQLLEIAKANAAAMCAK 2072
Score = 43.9 bits (102), Expect = 7e-04
Identities = 55/220 (25%), Positives = 91/220 (41%), Gaps = 18/220 (8%)
Query: 545 SASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSR----SR 600
S S A S S S S S+ RS SSYS+ + S SS++ RS +
Sbjct: 1073 SMMSPMADRSMMSMGADRSMMSSYSAADRSMMSSYSA--ADRSMMSSYTADRSMMSMAAD 1130
Query: 601 SFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQA----TKTTAPV 656
S++ S + + T + P + + P PP E + P PP PP+ T+ +A
Sbjct: 1131 SYTDSYTDTYTEAYMVPPLPPEEPPTMPPLPPEEPPMTPPLPPEEPPEGPALPTEQSALT 1190
Query: 657 PEPTKPGDPREARRKERPAR-TPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSV-- 713
E T P + + +E ++ PP ++ S + YS S+S L + +V
Sbjct: 1191 AENTWPTEVPSSPSEESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPE 1250
Query: 714 -----SSATSSSSSAHSVDSEDMYADLASPVSSASSRSPA 748
S+ + + +V +E+ PV+ S +PA
Sbjct: 1251 PPPEPESSITLTPVESAVVAEEHEVVPERPVTCMVSETPA 1290
>gi|167234419 thyroid hormone receptor associated protein 3 [Homo
sapiens]
Length = 955
Score = 86.7 bits (213), Expect = 1e-16
Identities = 134/604 (22%), Positives = 216/604 (35%), Gaps = 97/604 (16%)
Query: 402 RERERERERENR-QRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKR 460
R R R R + R R R R R+RR R R R + R+R + R R
Sbjct: 15 RSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQNRDFR 74
Query: 461 DEKDRQHRD---RDREKE-----REKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRA 512
R R R + + G RS RQA P++ + +
Sbjct: 75 GHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRSRS------- 127
Query: 513 DEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSR--SSSRSSSYSGSGSS 570
+ P RRS SP+ + S + R + S+SS S+SN SR SS R S+ SS
Sbjct: 128 ---RSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSS 184
Query: 571 RSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPG 630
+ S + ++ +FSG S+ S S P P + S +
Sbjct: 185 KDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSP 244
Query: 631 KAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSG 690
+ ++K P + + +PVP+P+ P P SG+G
Sbjct: 245 RERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLP----------SGAGYQ 294
Query: 691 SGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLA-----------SPV 739
SG+ S SLS S S V + S+ S + ++ A
Sbjct: 295 SGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKT 354
Query: 740 SSASSRSPAPAQTRKEKGKSK---KEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPST 796
+ + T KEK K K + G+ + K K DS S KP G SQ P
Sbjct: 355 ENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRG---SQSPKR 411
Query: 797 PQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKR------------------------ 832
+ + + F HKE ++ +K KG ++
Sbjct: 412 YKLRDDFEKKMADF--HKE-EMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKS 468
Query: 833 -------YEPSDKDRQSPPPAKRPNTSPDRGSRD----RKSGGRLGSPKPERQRGQNSKA 881
Y P K++Q + P+R ++ R GG G PE+ N +
Sbjct: 469 GKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGF-VPEK----NFRV 523
Query: 882 PAAPADRKRQLSPQSKSSSKVTSVPGKASDPGAASTKSGKAS-TLSRREELLKQLKAVED 940
A A +++ SP + +S+ G D +GK+S +++R ++ ++ + ++
Sbjct: 524 TAYKAVQEKSSSPPPRKTSESRDKLGAKGD-----FPTGKSSFSITREAQVNVRMDSFDE 578
Query: 941 AIAR 944
+AR
Sbjct: 579 DLAR 582
Score = 63.2 bits (152), Expect = 1e-09
Identities = 114/528 (21%), Positives = 171/528 (32%), Gaps = 92/528 (17%)
Query: 367 YADPYYD-------YEIERFWRGGQYENFRVQYTE-TEPYHNYRERERERERENRQ---R 415
Y PYY Y ++ RGG Y N+R + + Y R R R R + R R
Sbjct: 80 YRRPYYFRGRNRGFYPWGQYNRGG-YGNYRSNWQNYRQAYSPRRGRSRSRSPKRRSPSPR 138
Query: 416 ERERERERDR---ERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDR 472
R R D+ +R RR H R E +RK E++ + +D + Q D
Sbjct: 139 SRSHSRNSDKSSSDRSRRSSSSRSSSNHSR-VESSKRKSAKEKKSSSKDSRPSQAAG-DN 196
Query: 473 EKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVS 532
+ + KE+ S + ++ P +A RA + R +SP K +
Sbjct: 197 QGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPRERSPALKSPLQ 256
Query: 533 VSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSF 592
R R R + S SS S S+ SG+G Y S + +
Sbjct: 257 SVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAG----------YQS-GTHQGQFDHG 305
Query: 593 SGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKT 652
SGS S S+ SP T S + S K E A G A K +
Sbjct: 306 SGSLSPSKKSPVGKSPPSTGSTYGSS--QKEESAASGGAAYTKRYLE------------- 350
Query: 653 TAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSS 712
+ T+ G +E ++ + + S +G G G
Sbjct: 351 ----EQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGK------------------- 387
Query: 713 VSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKR 772
S S A DSE + SP K + +D K + RK
Sbjct: 388 ----MKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKE 443
Query: 773 DSSTQPPKSAKPPAGGKSSQQPSTPQQ------APPGQPQQGTFVAHKEIKLTLLNKAAD 826
PK G +Q+ + APPG+ +Q +E +K D
Sbjct: 444 SEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKED 503
Query: 827 KGSRKR----------------YEPSDKDRQSPPPAKRPNTSPDRGSR 858
+G R Y+ + SPPP K + G++
Sbjct: 504 RGKRSEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGAK 551
Score = 57.0 bits (136), Expect = 8e-08
Identities = 104/413 (25%), Positives = 161/413 (38%), Gaps = 56/413 (13%)
Query: 550 SASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPS 609
S +N S+S SRSS + SRSRS S S S S S SRSRSRS+ SP+
Sbjct: 2 SKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSY----SPA 57
Query: 610 PTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKP--GDPRE 667
+ P + + + + ++P + P + + G+ R
Sbjct: 58 HNRERNHPRVYQNRD-----FRGHNRGYRRPYYFRG---RNRGFYPWGQYNRGGYGNYRS 109
Query: 668 ARRKERPARTPPRRRTLSGSGS-GSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSV 726
+ R A +P R R+ S S S S S S SR+ S S S SS++ SSS+ V
Sbjct: 110 NWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRV 169
Query: 727 DSEDMYADLASPVSSASSR-SPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPP 785
+S + SS SR S A + ++ K + G + K S++P A
Sbjct: 170 ESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYG 229
Query: 786 AGG---KSSQQPSTPQQAPPG--QPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDR 840
G S+ +P++ P P Q V R+ PS +
Sbjct: 230 TGSASRASAVSELSPRERSPALKSPLQSVVV-----------------RRRSPRPSPVPK 272
Query: 841 QSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSS 900
SPP + +TS + +G + G+ + + G S +P+ + SP KS
Sbjct: 273 PSPPLS---STSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPS-------KKSPVGKSPP 322
Query: 901 KVTSVPG------KASDPGAASTKS--GKASTLSRREELLKQLKAVEDAIARK 945
S G A+ GAA TK + T + +++ KQ ++ I K
Sbjct: 323 STGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKIKEK 375
Score = 43.1 bits (100), Expect = 0.001
Identities = 60/276 (21%), Positives = 98/276 (35%), Gaps = 25/276 (9%)
Query: 685 SGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASS 744
S SGS S S S S SRSRS S S S S + S S Y SP +
Sbjct: 7 SKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSY----SPAHNRER 62
Query: 745 RSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQ 804
P Q R +G ++ G + R + + GG + + +
Sbjct: 63 NHPRVYQNRDFRGHNR---GYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYS 119
Query: 805 PQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGG 864
P++G + K R R + D+ S ++R ++S + R
Sbjct: 120 PRRGRSRSRSP-------KRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESS 172
Query: 865 RLGSPKPERQRGQNSKAPAAPADRKRQ----------LSPQSKSSSKVTSVPGKASDPGA 914
+ S K ++ ++S+ A D + S +K+S P G+
Sbjct: 173 KRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGS 232
Query: 915 ASTKSGKASTLSRREELLKQLKAVEDAIARKRAKIP 950
AS ++ S LS RE ++ + R+R+ P
Sbjct: 233 AS-RASAVSELSPRERSPALKSPLQSVVVRRRSPRP 267
Score = 40.4 bits (93), Expect = 0.008
Identities = 38/154 (24%), Positives = 61/154 (39%), Gaps = 8/154 (5%)
Query: 440 HERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPK 499
HER + +R E E + K+ + + D R+ + +SP+ P +AE
Sbjct: 651 HERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKY 710
Query: 500 KEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSS 559
K+ D D RR K ++ L S R + + SA + ++
Sbjct: 711 KDDPV--------DLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHK 762
Query: 560 RSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFS 593
S +R RSRSSS SS SS S + ++
Sbjct: 763 GSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYT 796
Score = 40.4 bits (93), Expect = 0.008
Identities = 42/202 (20%), Positives = 76/202 (37%), Gaps = 15/202 (7%)
Query: 417 RERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKER 476
R++ +ERD +R + RE R+ +ER K E + +K+ +K R+ RDR R
Sbjct: 724 RKKHKERDLKRGK-SRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSS 782
Query: 477 EKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPS 536
+ S + E ++E +TTG R + + G +
Sbjct: 783 SSQSS----HSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFRA 838
Query: 537 RAR---RRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRS-------RSSSYSSYSSRS 586
R R R + ++ +++N + +R + + +S+ + SR
Sbjct: 839 RGRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTPKSKKYYLHDDREGEGSDKWVSRG 898
Query: 587 SRHSSFSGSRSRSRSFSSSPSP 608
+F R R SS SP
Sbjct: 899 RGRGAFPRGRGRFMFRKSSTSP 920
Score = 37.0 bits (84), Expect = 0.088
Identities = 89/427 (20%), Positives = 146/427 (34%), Gaps = 57/427 (13%)
Query: 509 VKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSG 568
+ + ++ K R S+S S S S++R R ++ + S SSRS SRS S
Sbjct: 1 MSKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYS---PA 57
Query: 569 SSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEP--- 625
+R R+ Y + R R R+ P + + R+ +
Sbjct: 58 HNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGY-GNYRSNWQNYRQ 116
Query: 626 --APPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRT 683
+P G++ +S K+ +P P ++ + K R R+ +R+
Sbjct: 117 AYSPRRGRSRSRSPKRRSPSPRSRSHSRNS------DKSSSDRS--RRSSSSRSSSNHSR 168
Query: 684 LSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSAT------SSSSSAHSVDSEDMYADLAS 737
+ S S SS SR + + A +S + +S + D
Sbjct: 169 VESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATY 228
Query: 738 PVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTP 797
SAS S + +E+ + K R+R P PP S + P
Sbjct: 229 GTGSASRASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLP 288
Query: 798 QQAP-PGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRG 856
A QG F D GS PS K SP P+T G
Sbjct: 289 SGAGYQSGTHQGQF---------------DHGSGS-LSPSKK---SPVGKSPPSTGSTYG 329
Query: 857 SRDRK----SGGRLGSPK-PERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGKASD 911
S ++ SGG + + E Q+ +N K D++++ Q+ + + G SD
Sbjct: 330 SSQKEESAASGGAAYTKRYLEEQKTENGK------DKEQK---QTNTDKEKIKEKGSFSD 380
Query: 912 PGAASTK 918
G K
Sbjct: 381 TGLGDGK 387
Score = 34.7 bits (78), Expect = 0.44
Identities = 15/61 (24%), Positives = 28/61 (45%)
Query: 402 RERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRD 461
R+ RER + E+ + + +++ RR R+R R + EE+ E +R+
Sbjct: 744 RDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEERE 803
Query: 462 E 462
E
Sbjct: 804 E 804
Score = 33.1 bits (74), Expect = 1.3
Identities = 23/95 (24%), Positives = 44/95 (46%), Gaps = 5/95 (5%)
Query: 394 ETEPYHNYREREREREREN-RQRERERERERDRER-ERRQREREREREHERDKERQRRKE 451
E H R+ +R + RE+ R+ RER E+ E+ + +++++H R ++R R
Sbjct: 722 ERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSS 781
Query: 452 EWERERAKRDEKDRQHRDRDREKEREKEKGKPKPR 486
++ K ++ + E+E E G K R
Sbjct: 782 --SSSQSSHSYKAEEYTEETEERE-ESTTGFDKSR 813
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 86.3 bits (212), Expect = 1e-16
Identities = 118/523 (22%), Positives = 201/523 (38%), Gaps = 64/523 (12%)
Query: 458 AKRDEKDRQHRDRDREKEREKE-KGKPKPRSPQPPSRQAEPPKKEA--ATTGPQVKRADE 514
AK+ +K D + E E+E +G P ++ P R PP K A A+ + + +
Sbjct: 75 AKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSD 134
Query: 515 WKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSS--------------R 560
D + K P +K GV A+ K + SS S S+SS +
Sbjct: 135 DDDEEDQKKQPVQK-GVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVK 193
Query: 561 SSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSP----------SPSP 610
+ + + +R+ + ++ + SS SS SS S S +++P + +P
Sbjct: 194 AQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAP 253
Query: 611 TPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARR 670
+ P+ K + E+ KKP P ++ VP P+ P P+++
Sbjct: 254 VKAATTPT--RKSSSSEDSSSDEEEEQKKPMKNKPGPYSS-----VPPPSAP-PPKKSLG 305
Query: 671 KERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVS--------SATSSSSS 722
+ P + +++ + S S S S S + + + VS + +A SSS S
Sbjct: 306 TQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDS 365
Query: 723 AHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKG-------KSKKEDGVKEEKRKRDSS 775
+ S SED A + P + + S PA T K K G K RK DSS
Sbjct: 366 SDSDSSEDDEAP-SKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSS 424
Query: 776 TQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEP 835
+ +S+ SS++ T + +P+ A + L+L K A +GSR
Sbjct: 425 SSEEESS-------SSEEEKTKKMVATTKPK-----ATAKAALSLPAKQAPQGSRDSSSD 472
Query: 836 SDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQ 895
SD K ++ + + G P ++ S ++ D + +
Sbjct: 473 SDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEK 532
Query: 896 SKSSSKVTSVPGKASDPGAASTKSGKASTLSRREELLKQLKAV 938
K KA+ A + ++GKA+ S EE K+ AV
Sbjct: 533 LKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAV 575
Score = 71.2 bits (173), Expect = 4e-12
Identities = 79/367 (21%), Positives = 138/367 (37%), Gaps = 23/367 (6%)
Query: 460 RDEKDRQHRDRDREKEREKE-KGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDP 518
R + D E+E++K K KP P S PP A PPKK T P K+A E + P
Sbjct: 262 RKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPP-SAPPPKKSLGTQPP--KKAVEKQQP 318
Query: 519 WRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSS 578
S+ + S S S ++ T A + A+ + +++ S S S
Sbjct: 319 VESSEDSSDE---SDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDE 375
Query: 579 YSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPS------IRTKGEPAPPPGKA 632
S + ++++SS ++ + SP+ P +P +P + K + + ++
Sbjct: 376 APSKPAGTTKNSS-----NKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEES 430
Query: 633 G---EKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARR-KERPARTPPRRRTLSGSG 688
E+ KK P K +P P R++ + + +T +
Sbjct: 431 SSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAV 490
Query: 689 SGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPA 748
+G ++ S+ S S+ SSSS S + E+ SP A +
Sbjct: 491 KKKPQKVAGGAAPSKPASAKK-GKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGT 549
Query: 749 PAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQG 808
A T + +K + +EEK+K S K +++++ TPQ
Sbjct: 550 SALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPN 609
Query: 809 TFVAHKE 815
TF K+
Sbjct: 610 TFPKRKK 616
Score = 47.0 bits (110), Expect = 8e-05
Identities = 114/598 (19%), Positives = 204/598 (34%), Gaps = 113/598 (18%)
Query: 4 AESPER--DPHSPEDEEQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEE--------- 52
A+ PER + P ++ + S D S ++++ G + + + +
Sbjct: 61 AKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAA 120
Query: 53 -SAARGPSQEEEDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSD 111
A+ S EE + DEED+ +P + V ++ + P + + + + D +S+
Sbjct: 121 AKASESSSSEESSDDDDEEDQKKQPVQKG----VKPQAKAAKAPPKKAKSSDSDSDSSSE 176
Query: 112 LRDEASSVTR-ELDEHELDYDEEVPEEPAPAVQEDEAEKAGA------------EDDEEK 158
DE + ++ + + P +PA A + KA + + +EEK
Sbjct: 177 --DEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEK 234
Query: 159 GEGTPREEGKAGVQSVGEKESLEAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKV 218
TP++ + V K ++AA ++ E D EE E K P
Sbjct: 235 AAATPKKT--VPKKQVVAKAPVKAATTPTRKSSSSE------DSSSDEEEEQKKP----- 281
Query: 219 RPRPTCRFFMKGNCTWGMNCRFIHPGVNDKGNYSLITKADPFPPNGAPP----LGPHPLM 274
MK N G YS + PP APP LG P
Sbjct: 282 ---------MK----------------NKPGPYSSV------PPPSAPPPKKSLGTQPPK 310
Query: 275 PANPWGGPVVDEILPPPPPEPPTESAWERGLRHAKEVLKKATIRKEQEPDFEEKRFTVT- 333
A PV + S+ E K V+ KAT + E +
Sbjct: 311 KAVEKQQPVESS---EDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSD 367
Query: 334 --IGEDEREFDKENEVFRDWNSRIPRDVRDTVLEPYADPYYDY--------------EIE 377
ED+ K ++ +++ + ++P A P E
Sbjct: 368 SDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSE 427
Query: 378 RFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERERRQRERERE 437
+ E + T+P + ++ Q R+ + D + E+ +
Sbjct: 428 EESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSK 487
Query: 438 REHERDKER----QRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSR 493
++ ++ + ++ K + + D E+E EK KGK PR PQ P
Sbjct: 488 SAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPR-PQAP-- 544
Query: 494 QAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASA 551
+A A G K ++E + KKK V VS S + ++RK + ++ A
Sbjct: 545 KANGTSALTAQNGKAAKNSEE-------EEEEKKKAAVVVSKSGSLKKRKQNEAAKEA 595
Score = 42.4 bits (98), Expect = 0.002
Identities = 63/299 (21%), Positives = 104/299 (34%), Gaps = 27/299 (9%)
Query: 653 TAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSS 712
+A VPE + A++ ++ A + + G ++ ++ + + +
Sbjct: 60 SAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKA 119
Query: 713 VSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKR 772
+ A+ SSSS S D +D PV A+ +K KS D
Sbjct: 120 AAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDS------DS 173
Query: 773 DSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKR 832
S +PPK+ KP K + Q P +P + A K + ++ S
Sbjct: 174 SSEDEPPKNQKP----KITPVTVKAQTKAPPKPAR---AAPKIANGKAASSSSSSSSSSS 226
Query: 833 YEPSDKDRQSPPP----------AKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAP 882
+ S++++ + P AK P + +R S S + E Q+ P
Sbjct: 227 SDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKP 286
Query: 883 AAPADRKRQLSPQSKSSSKVTSVPGKA---SDPGAASTKSGKASTLSRREELLKQLKAV 938
+ +P K S T P KA P +S S S S EE KAV
Sbjct: 287 GPYSSVPPPSAPPPKKSLG-TQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAV 344
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 86.3 bits (212), Expect = 1e-16
Identities = 146/611 (23%), Positives = 222/611 (36%), Gaps = 110/611 (18%)
Query: 402 RERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRD 461
R R ++ E + + +R R R E+ + DK W+ +
Sbjct: 346 RSRSCSESDDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQR 405
Query: 462 EKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRR 521
+ + + + G K R + + + KK+ RR
Sbjct: 406 SRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHC---------------RR 450
Query: 522 SKSPKKK---LGVSVSPSRARRRRKTSASSASASNSSRSSSRSS---------------- 562
K KK+ + + S++ RR S S SSRSSS SS
Sbjct: 451 HKQTKKRRILIPSDIESSKSSTRRMKS--SCDRERSSRSSSLSSHHSSKRDWSKSDKDVQ 508
Query: 563 ---SYSGSGSSRSRSRSSSYSSYSSRS---SRHSSFSGSRSRSRSFS-------SSPSPS 609
++S S RS+S S SYS SSRS S+ SS S SRS+SRS S +S SP
Sbjct: 509 SSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPR 568
Query: 610 PTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGD----P 665
T S + K EP E V +P P + +P P KPG P
Sbjct: 569 KTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKP 628
Query: 666 REARRKERPARTP---PRRRTLSGSG---SGSGSSY-----SGSSSRSRSLSVSSVSSVS 714
R +E A+T P + T S + +GS SSY + S +S S SS S
Sbjct: 629 SYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSES 688
Query: 715 SATSSSSSAHSVDSEDMYADLASPVSSAS-SRSPAPAQTRKEKGKS-------------K 760
S S S S+ S Y S SS S SRSP+ + K
Sbjct: 689 SPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSIS 748
Query: 761 KEDGVKEEKRKRDSSTQPPKSAKPPAGG--------------------KSSQQPSTPQQA 800
+DG + ++R R S + S K + K S+ S+ +
Sbjct: 749 SDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYS 808
Query: 801 PPGQPQ--QGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPD---- 854
+ Q T A ++ K + + +K + R E K + P +K+ +
Sbjct: 809 SDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSDH 868
Query: 855 --RGSRDRK---SGGRLGS-PKPERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGK 908
GS+ ++ +G + S ER +NSK + P+ K + S S S+V+ + K
Sbjct: 869 LRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIK 928
Query: 909 ASDPGAASTKS 919
+ST +
Sbjct: 929 VKPTTKSSTNT 939
Score = 65.1 bits (157), Expect = 3e-10
Identities = 129/594 (21%), Positives = 214/594 (36%), Gaps = 63/594 (10%)
Query: 403 ERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDE 462
E E E E+ +R R R+ +R + +R ++ R+ E + + + ER+ +E
Sbjct: 209 ESSSESELEH-ERSRRRKHKRRPKVKRSKKRRKEASSSEEPRNKHAMNPKGHSERSDTNE 267
Query: 463 KDRQHRDRDREKEREKEKGKPKPRSPQPPSR----------QAEP-------------PK 499
K R D +REK +P+ P P +R AEP K
Sbjct: 268 K----RSVDSSAKREKPVVRPEEIPPVPENRFLLRRDMPVVTAEPEPKIPDVAPIVSDQK 323
Query: 500 KEAATTGPQVKRADEWK---DPWRRSKSPKKKLGVSVSP-----SRARRRRKTSASSASA 551
+ +G ++K + P RS S S +P R R S
Sbjct: 324 PSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDSSETPPHWKEEMQRLRAYRPPSGEKW 383
Query: 552 SNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSS--RSSRHSSFSGSRSRSRSFSSSPSPS 609
S + S SS S RSRS SY+ Y S ++RHS R + +
Sbjct: 384 SKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGK 443
Query: 610 PTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREAR 669
R K P KS + + + ++ + + R+
Sbjct: 444 KQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSL--SSHHSSKRDWS 501
Query: 670 RKERPARTPPRRRTLSGSGSGSGS-SYSGSSSRSRSLSVSS--VSSVSSATSSSSSAHSV 726
+ ++ ++ + S S S SYS SSRSR+ S SS S S + SSS S H
Sbjct: 502 KSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRK 561
Query: 727 DSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPA 786
+ AS +S P + ++ E+ V + + P + PP+
Sbjct: 562 RASKSPRKTASQLSENKPVKTEPLRAT----MAQNENVVVQPVVAENIPVIPLSDSPPPS 617
Query: 787 GGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPP- 845
K Q+P P + + T L + GS Y +K+ +S
Sbjct: 618 RWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQST 677
Query: 846 ----AKRPNTSPDRGSRDRKSGGRLGSPKPERQRG-----QNSKAPAAPADRKRQLSPQS 896
+ R + S R SR R S R S R R S++P++ + + + S S
Sbjct: 678 YSKYSDRSSESSPR-SRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHS 736
Query: 897 KSSSKVTSVPGKASDPGAASTK----SGKASTLSRREELLKQLKAVEDAIARKR 946
+ S+ +S +SD G + + SGK +++S ++ K + + R
Sbjct: 737 Q-CSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGR 789
Score = 60.5 bits (145), Expect = 7e-09
Identities = 51/139 (36%), Positives = 68/139 (48%), Gaps = 20/139 (14%)
Query: 478 KEKGKPKPRS----PQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSV 533
K K K +P S + +R P+ + +++ Q D+ +S+SP + S
Sbjct: 1267 KSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDS----QSRSPSRSRSKSE 1322
Query: 534 SPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGS------SRSRSRSSSYSSYSSRSS 587
+ SR R R + + S S S SS SS RS SYS S S R+RSRSSSY SY S +
Sbjct: 1323 TKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRT 1382
Query: 588 RHSSFSGSRSRSRSFSSSP 606
SRSRSRS S P
Sbjct: 1383 ------SSRSRSRSSSYDP 1395
Score = 53.1 bits (126), Expect = 1e-06
Identities = 95/419 (22%), Positives = 147/419 (35%), Gaps = 67/419 (15%)
Query: 539 RRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSR 598
+R++ T + + +S++S SSS SSS S RSR R + R S+ R
Sbjct: 188 KRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRR---------KHKRRPKVKRSKKR 238
Query: 599 SRSFSSSPSP----SPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAP-PPAP------- 646
+ SSS P + P H T + + EK V +P PP P
Sbjct: 239 RKEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLR 298
Query: 647 ---PQAT-------KTTAPVPEPTKPGDPREARR-KERPA---RTPPRRRTLSGSGSGSG 692
P T AP+ KP + R+ K R TPPR R+ S S
Sbjct: 299 RDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDS 358
Query: 693 SS----YSGSSSRSRSLSVSS-------------VSSVSSATSSSSSAHSVDSEDMYADL 735
S + R R+ S SS S S + S Y+DL
Sbjct: 359 SETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDL 418
Query: 736 ASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPP--AGGKSSQQ 793
S + S + RKEK K+ G K++ +R T+ + P KSS +
Sbjct: 419 -----STARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTR 473
Query: 794 PSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSP 853
+ + +H K D S + D R +K + S
Sbjct: 474 RMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYR-----SKSHSQSY 528
Query: 854 DRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGKASDP 912
RGS ++ + S R + S++ + RKR K++S+++ ++P
Sbjct: 529 SRGSSRSRTASKSSSHSRSRSK---SRSSSKSGHRKRASKSPRKTASQLSENKPVKTEP 584
Score = 52.0 bits (123), Expect = 3e-06
Identities = 55/187 (29%), Positives = 74/187 (39%), Gaps = 23/187 (12%)
Query: 438 REHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEP 497
R+ R R R +E E+ + D Q R R + + + K + + RS S
Sbjct: 1282 RKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSV---SYSHSR 1338
Query: 498 PKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRS 557
+ ++T+ + RS S + G S R R R + S S SSRS
Sbjct: 1339 SRSRSSTSSYR-----------SRSYSRSRSRGW-YSRGRTRSRSSSYRSYKSHRTSSRS 1386
Query: 558 SSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRS--------RSFSSSPSPS 609
SRSSSY SRS + S YS SRS S S R RS RS+ S
Sbjct: 1387 RSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESD 1446
Query: 610 PTPSPHR 616
+ S HR
Sbjct: 1447 RSYSHHR 1453
Score = 51.6 bits (122), Expect = 3e-06
Identities = 132/579 (22%), Positives = 199/579 (34%), Gaps = 162/579 (27%)
Query: 407 ERERENRQRERERERERDRERERRQREREREREHE-RDKERQR-RKEEWER--ERAKRDE 462
+RER +R R+ + ++ + H RD R + + + R R++
Sbjct: 480 DRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTAS 539
Query: 463 KDRQHRDRDREKEREKEKGKPKPRSPQPPSRQA------EPPKKE--------------- 501
K H R R K R K + R+ + P + A +P K E
Sbjct: 540 KSSSH-SRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQ 598
Query: 502 --AATTGPQVKRADE------------WKDPWRRSKSPKKK---------------LGVS 532
A P + +D WK + R + K K + +
Sbjct: 599 PVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKET 658
Query: 533 VSPSRARRRRKTSASSASA-SNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSS 591
S S +R K S S S S S SS SS S S SSRSRS S SY
Sbjct: 659 GSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSY------------ 706
Query: 592 FSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATK 651
+RSRS +SS S S +PS S + + + S+
Sbjct: 707 -----TRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSD----------- 750
Query: 652 TTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSS----SRSRSLSV 707
+ RR +R R+ ++ ++S S S + S R RS V
Sbjct: 751 ---------------DGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCV 795
Query: 708 SSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKE 767
S S SS +S DSE S V + S Q + E+ +K+E E
Sbjct: 796 RKYSE-----SRSSLDYSSDSEQ------SSVQATQSAQEKEKQGQMERTHNKQEKNRGE 844
Query: 768 EKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLN--KAA 825
EK K S + P S K + +K L + +
Sbjct: 845 EKSK--SERECPHSKK------------------------------RTLKENLSDHLRNG 872
Query: 826 DKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAP 885
K RK Y S D +S N+ D +++ K+ S K E + +S++ +
Sbjct: 873 SKPKRKNYAGSKWDSES-------NSERD-VTKNSKNDSHPSSDKEEGEATSDSESEVSE 924
Query: 886 ADRKRQLSPQSKSSSKVTSVPGKASDPGAASTKSGKAST 924
K + P +KSS+ TS+P D GA + + ST
Sbjct: 925 IHIK--VKPTTKSSTN-TSLP---DDNGAWKSSKQRTST 957
Score = 50.4 bits (119), Expect = 8e-06
Identities = 59/211 (27%), Positives = 83/211 (39%), Gaps = 26/211 (12%)
Query: 404 RERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEK 463
+ + + R + R+ R R R Q E+ RD + Q R R R+K + K
Sbjct: 1267 KSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPS--RSRSKSETK 1324
Query: 464 DRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWR-RS 522
R HR R + + + S + S R+ W R RS
Sbjct: 1325 SR-HRTRSVSYSHSRSRSRSSTSSYRSRSYSRS--------------RSRGWYSRGRTRS 1369
Query: 523 KSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRS-RSSSY-- 579
+S + S R R ++ +SS + SRS + S YS S SRSRS RS SY
Sbjct: 1370 RSSSYR---SYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRS-RSRSRSQRSDSYHR 1425
Query: 580 -SSYSSRSSRHSSFSGSRSRSRSFSSSPSPS 609
SY+ RS S+ RS+S SPS
Sbjct: 1426 GRSYNRRSRSCRSYGSDSESDRSYSHHRSPS 1456
Score = 47.8 bits (112), Expect = 5e-05
Identities = 72/330 (21%), Positives = 121/330 (36%), Gaps = 67/330 (20%)
Query: 532 SVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYS--SRSSRH 589
S S R+R R S S + + SRS + S S S S SSRS SR+ YS +S SRSS +
Sbjct: 686 SESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNK-YSDHSQCSRSSSY 744
Query: 590 SSFS---GSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPP--- 643
+S S G R++ R SS S + H S G+ V+K +
Sbjct: 745 TSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSS 804
Query: 644 -----PAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPR-----------RRTLSGS 687
+ + + T E K G K+ R + +RTL +
Sbjct: 805 LDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTLKEN 864
Query: 688 GSG-------------SGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYAD 734
S +GS + S+ R ++ +S + ++ + DSE ++
Sbjct: 865 LSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVSE 924
Query: 735 L---ASPVSSASSRSPAP----------------------AQTRKEKGKSKKEDGVKEEK 769
+ P + +S+ + P + + +GK +K +E
Sbjct: 925 IHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKEN 984
Query: 770 RKRDSSTQPPKSAKPPAGGKSSQQPSTPQQ 799
KR+ + K K GK ++ P++
Sbjct: 985 LKREHT----KKVKEKLKGKKDKKHKAPKR 1010
Score = 46.6 bits (109), Expect = 1e-04
Identities = 50/197 (25%), Positives = 75/197 (38%), Gaps = 16/197 (8%)
Query: 398 YHNYRERERERERENRQRERERERERDRERERRQREREREREHERDKERQR-RKEEWERE 456
+ R+ R R Q E+ R+ + + R R R K R R R +
Sbjct: 1278 FDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHS 1337
Query: 457 RAKRDEKDRQHRDRDREKEREK---EKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRAD 513
R++ +R R + R + +G+ + RS S K T+ R+
Sbjct: 1338 RSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSY------KSHRTSSRSRSRSS 1391
Query: 514 EWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSR 573
+ DP RS+S S SR+R R + S S + +R S SY GS
Sbjct: 1392 SY-DPHSRSRS--YTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSY---GSDSES 1445
Query: 574 SRSSSYSSYSSRSSRHS 590
RS S+ S SSR+S
Sbjct: 1446 DRSYSHHRSPSESSRYS 1462
Score = 46.6 bits (109), Expect = 1e-04
Identities = 43/114 (37%), Positives = 58/114 (50%), Gaps = 9/114 (7%)
Query: 513 DEWKDPWRRSKSPKKKLGVSVSPSRAR----RRRKTSASSASASNSSRSSSRSSSYSGSG 568
DE + R ++ P+ + S + +R + R S S + + SR +RS SYS
Sbjct: 1279 DEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYS--- 1335
Query: 569 SSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTK 622
SRSRSRSS+ SSY SRS S G SR R+ S S S S HR S R++
Sbjct: 1336 HSRSRSRSST-SSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKS-HRTSSRSR 1387
Score = 38.9 bits (89), Expect = 0.023
Identities = 43/222 (19%), Positives = 80/222 (36%), Gaps = 4/222 (1%)
Query: 423 RDRER-ERRQREREREREHERDKERQR-RKEEWERERAKRDEKDRQHRDRDREKEREKEK 480
RDR R+ E ++ D E+ + + +E+ K+ + +R H + EK R +EK
Sbjct: 789 RDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQ--EKNRGEEK 846
Query: 481 GKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARR 540
K + P R + + G + KR + W + ++ + +
Sbjct: 847 SKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPS 906
Query: 541 RRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSR 600
K + S S S S + SS + S ++ S R S+ S S
Sbjct: 907 SDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSN 966
Query: 601 SFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAP 642
S ++ P + +++ + G+K K AP
Sbjct: 967 SENNRGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKAP 1008
Score = 38.5 bits (88), Expect = 0.030
Identities = 51/234 (21%), Positives = 94/234 (40%), Gaps = 31/234 (13%)
Query: 4 AESPERDPHSPEDEEQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQEEE 63
++S PHS + + LSD LR+ + + AG + + E S+ +
Sbjct: 847 SKSERECPHSKK-RTLKENLSDH--LRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDS 903
Query: 64 DNHSDEEDRASEPKSQDQDSEVNEL---------SRGPTSSPCEEEGDEGEEDRTSDLRD 114
SD+E+ + + D +SEV+E+ S TS P + + + RTS
Sbjct: 904 HPSSDKEEGEA---TSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDS 960
Query: 115 EASSVTRELD-----EHELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGE--------G 161
E S E + +H+ E + E V+E + G +D + K
Sbjct: 961 EGSCSNSENNRGKPQKHKHGSKENLKREHTKKVKE---KLKGKKDKKHKAPKRKQAFHWQ 1017
Query: 162 TPREEGKAGVQSVGEKESLEAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSD 215
P E G+ + + +K+ + +KEKK +++ I D + + E ++ D
Sbjct: 1018 PPLEFGEEEEEEIDDKQVTQESKEKKVSENNETIKDNILKTEKSSEEDLSGKHD 1071
Score = 37.4 bits (85), Expect = 0.067
Identities = 40/225 (17%), Positives = 82/225 (36%), Gaps = 12/225 (5%)
Query: 391 QYTETEPYHNYRERERERERENRQRERERERERDRERERRQRER---------EREREHE 441
+Y+E+ +Y + + Q +E+E++ ER ++E+ ERE H
Sbjct: 797 KYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHS 856
Query: 442 RDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKE 501
+ + + + R +K K+ D E E++ K P S + E +
Sbjct: 857 KKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEE--GEA 914
Query: 502 AATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRS 561
+ + +V P +S + + + +++R TS S S SNS + +
Sbjct: 915 TSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKP 974
Query: 562 SSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSP 606
+ GS + R + + + R ++F P
Sbjct: 975 QKHK-HGSKENLKREHTKKVKEKLKGKKDKKHKAPKRKQAFHWQP 1018
Score = 34.3 bits (77), Expect = 0.57
Identities = 57/253 (22%), Positives = 93/253 (36%), Gaps = 34/253 (13%)
Query: 540 RRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRS 599
++ + + S + S S+S + +G S + + S + + G + +
Sbjct: 1177 KQESSMSESKVLGEVGKQDSSSASLASAGESTGKKEVAEKSQINLIDKKWKPLQGVGNLA 1236
Query: 600 RSFSSSPSPS--------PTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATK 651
+++ S P P I K + PG ++ V+K A P+ +
Sbjct: 1237 APNAATSSAVEVKVLTTVPEMKPQGLRIEIKSKNKVRPGSLFDE-VRKTARLNRRPRNQE 1295
Query: 652 TTAPVPEPTKPGDP--REARRKERPARTPPRRRTLSGSGSGSGS------------SYSG 697
+++ P++ D R R + T R RT S S S S S SYS
Sbjct: 1296 SSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSR 1355
Query: 698 SSSR---------SRSLSVSSVSS--VSSATSSSSSAHSVDSEDMYADLASPVSSASSRS 746
S SR SRS S S S SS + S SS++ S S S + SRS
Sbjct: 1356 SRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRS 1415
Query: 747 PAPAQTRKEKGKS 759
+ +G+S
Sbjct: 1416 RSQRSDSYHRGRS 1428
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 85.5 bits (210), Expect = 2e-16
Identities = 51/211 (24%), Positives = 107/211 (50%), Gaps = 7/211 (3%)
Query: 395 TEPYHNYRERERERERENRQ---RERERERERDR-ERERRQREREREREHER---DKERQ 447
T+P RERERE E R+ +ERE ER+++R ERE+R+RERE+ER+ ER +K+ +
Sbjct: 30 TQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGE 89
Query: 448 RRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGP 507
R+KEE ER++ +R++++++ ++++ K++EK++ + + R+ E ++E
Sbjct: 90 RKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER 149
Query: 508 QVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGS 567
+ + ++ ++ R K +K++G + + R++ + + R
Sbjct: 150 KKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERK 209
Query: 568 GSSRSRSRSSSYSSYSSRSSRHSSFSGSRSR 598
+ + +++ G R R
Sbjct: 210 KERKKKEERKKERQKDRQTNWREKERGKRER 240
Score = 82.0 bits (201), Expect = 2e-15
Identities = 62/242 (25%), Positives = 113/242 (46%), Gaps = 32/242 (13%)
Query: 294 EPPTESAWERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNS 353
+P T+ W+ +R + ++ RKE + + E +R ++R+ ++E E R+
Sbjct: 27 KPCTQPGWQSEIREREREIET---RKEGKKERESERKKERREREKRKREREKERKRERGK 83
Query: 354 RIPRDVRDTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERER------E 407
+ + R E ER R + EN + E +ER R E
Sbjct: 84 KEKKGERKKE-----------ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKE 132
Query: 408 RER-ENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQ 466
RER E R+RE +ERER +E ++RER+ ++ ER + ++ +E E+ER +R +++R
Sbjct: 133 RERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERN 192
Query: 467 HRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPK 526
++R +E+ER++ + + K R KKE Q R W++ R + K
Sbjct: 193 RKERKKERERKERRERKKERK-----------KKEERKKERQKDRQTNWREKERGKRERK 241
Query: 527 KK 528
++
Sbjct: 242 ER 243
Score = 67.4 bits (163), Expect = 6e-11
Identities = 41/108 (37%), Positives = 68/108 (62%), Gaps = 9/108 (8%)
Query: 386 ENFRVQYTETEPYHNYRERERER-ERENRQRERERERERDR------ERERRQRER-ERE 437
E R + E E RE+ERER ER+ R+R++ E+E +R ER++R+R R ER+
Sbjct: 138 ERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERK 197
Query: 438 REHERDKERQRRKEEWERERAKRD-EKDRQHRDRDREKEREKEKGKPK 484
+E ER + R+R+KE ++E K++ +KDRQ R++E+ + + K + K
Sbjct: 198 KERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 59.7 bits (143), Expect = 1e-08
Identities = 54/181 (29%), Positives = 96/181 (53%), Gaps = 16/181 (8%)
Query: 294 EPPTESAWERGLRHAK-EVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWN 352
E E ERG + K E K+ RK++ + E K GE++ + K+ + R
Sbjct: 72 EREKERKRERGKKEKKGERKKEERERKKRRREKENKE-----GEEKEKRKKKEKKERGRT 126
Query: 353 SRIPRDVRDTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYREREREREREN 412
S+ ++ R+ E + + E ++ R + E + E + E +E+ER+
Sbjct: 127 SKEGKE-RERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKE 185
Query: 413 RQRERERERERDRERER-----RQREREREREHERDKERQR-RKEEW-ERERAKRDEKDR 465
R++ RER R ++R++ER R+R++ER+++ ER KERQ+ R+ W E+ER KR+ K+R
Sbjct: 186 RKK-RERNR-KERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
Query: 466 Q 466
+
Sbjct: 244 K 244
Score = 56.6 bits (135), Expect = 1e-07
Identities = 44/182 (24%), Positives = 72/182 (39%), Gaps = 7/182 (3%)
Query: 426 ERERRQREREREREHERDKERQRRKEEWERERAKRD-EKDRQHRDRDREK--EREKEKGK 482
E R+RE E +E ++++E +R+KE ERE+ KR+ EK+R+ +EK ER+KE+ +
Sbjct: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERE 96
Query: 483 PKPRSPQPPSRQAEP----PKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRA 538
K R + +++ E KKE G K E + R + +K+
Sbjct: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156
Query: 539 RRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSR 598
R RK + R R R+R + R +
Sbjct: 157 ERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKE 216
Query: 599 SR 600
R
Sbjct: 217 ER 218
Score = 39.3 bits (90), Expect = 0.018
Identities = 39/157 (24%), Positives = 69/157 (43%), Gaps = 17/157 (10%)
Query: 44 RASDLEDEESAARGPSQEEEDNHSDEEDRAS--------EPKSQDQDSEVNELSRGPTSS 95
R + E E RG +++ + +E +R E + +++ + + RG TS
Sbjct: 69 RKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSK 128
Query: 96 PCEEEGDEGEEDRTSDLRDEASSVTRELDEHELDYD-EEVPEEPAPAVQEDEAEKAGAED 154
+E E +E+R R+E R+ +E E + + +E + V E E E+ E
Sbjct: 129 EGKER--ERKEERK---REERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKER 183
Query: 155 DEEKGEGTPREEGKAGVQSVGEKESLEAAKEKKKEDD 191
E K R+E K + KE E KE+KK+++
Sbjct: 184 KERKKRERNRKERK---KERERKERRERKKERKKKEE 217
Score = 38.5 bits (88), Expect = 0.030
Identities = 36/142 (25%), Positives = 58/142 (40%), Gaps = 12/142 (8%)
Query: 49 EDEESAARGPSQEEEDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGE--E 106
E E + + E+ E++R E +++ E + R E+E EGE E
Sbjct: 54 ERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKE 113
Query: 107 DRTSDLRDEASSVTRELDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREE 166
R + E ++E E E + + E +E E +K E + E+ E RE
Sbjct: 114 KRKKKEKKERGRTSKEGKERERKEERKREER-----KERERKKEEREKERERKERKKRER 168
Query: 167 GKAGVQSVGEKESLEAAKEKKK 188
+ VGEKE KE+K+
Sbjct: 169 -----KQVGEKEEERKEKERKE 185
Score = 36.6 bits (83), Expect = 0.11
Identities = 41/171 (23%), Positives = 73/171 (42%), Gaps = 15/171 (8%)
Query: 52 ESAARGPSQEEEDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSD 111
+S R +E E +++R SE K + ++ E + R E + + G++++ +
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREK-----ERKRERGKKEKKGE 89
Query: 112 LRDEASSVTRELDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDE-EKGEGTPREEGKAG 170
+ E + E E EE +E ++ E + E E E+ E REE K
Sbjct: 90 RKKEERERKKRRREKENKEGEE--KEKRKKKEKKERGRTSKEGKERERKEERKREERK-- 145
Query: 171 VQSVGEKESLEAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPR 221
+ +KE E +E+K+ GE + EE + K+ +RK R R
Sbjct: 146 -ERERKKEEREKERERKERKKRERKQVGEKE----EERKEKERKERKKRER 191
Score = 36.6 bits (83), Expect = 0.11
Identities = 34/166 (20%), Positives = 67/166 (40%), Gaps = 17/166 (10%)
Query: 751 QTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTF 810
+TRKE GK ++E K+E+R+R+ + + + GK ++ ++ + ++
Sbjct: 46 ETRKE-GKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRRE- 103
Query: 811 VAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTS---------------PDR 855
+KE + K +K R R K+R+ KR +R
Sbjct: 104 KENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKER 163
Query: 856 GSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSSK 901
R+RK G + E++R + K +RK++ + + K
Sbjct: 164 KKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERK 209
Score = 35.8 bits (81), Expect = 0.20
Identities = 31/152 (20%), Positives = 64/152 (42%), Gaps = 9/152 (5%)
Query: 751 QTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQP-QQGT 809
+ ++E+GK +K+ K+E+R+R + ++ + G+ ++ ++ G+ ++G
Sbjct: 76 ERKRERGKKEKKGERKKEERERKKRRREKENKE----GEEKEKRKKKEKKERGRTSKEGK 131
Query: 810 FVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSP 869
KE + + K ++ E +K+R+ KR +RK R
Sbjct: 132 ERERKEER----KREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERK 187
Query: 870 KPERQRGQNSKAPAAPADRKRQLSPQSKSSSK 901
K ER R + K R+R+ + K K
Sbjct: 188 KRERNRKERKKERERKERRERKKERKKKEERK 219
Score = 31.2 bits (69), Expect = 4.8
Identities = 42/149 (28%), Positives = 72/149 (48%), Gaps = 16/149 (10%)
Query: 294 EPPTESAWERGLRHAKEVLKKATIRKE-QEPDFEEKRFTVTIGEDEREFDKENEVFRDWN 352
E + E+ R KE ++ KE +E + +E+R E ER+ +E E R+
Sbjct: 103 EKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK-KEEREKERERK 161
Query: 353 SRIPRDVRDTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERER-E 411
R R+ R V E + E ER R + N + + E E RER++ER++ E
Sbjct: 162 ERKKRE-RKQVGEKEEERK---EKERKERKKRERNRKERKKERERKER-RERKKERKKKE 216
Query: 412 NRQRERERERERD--------RERERRQR 432
R++ER+++R+ + RER+ R++
Sbjct: 217 ERKKERQKDRQTNWREKERGKRERKERKK 245
>gi|50053795 eukaryotic translation initiation factor 4B [Homo
sapiens]
Length = 611
Score = 84.7 bits (208), Expect = 4e-16
Identities = 109/463 (23%), Positives = 175/463 (37%), Gaps = 72/463 (15%)
Query: 322 EPDFEEKRFTVTIGEDEREFDKENEVF-RDWNSRIPRDVRDTVLEPYADPYYDYEIERFW 380
E +R V + + ++ D+++ F RD N + D P D + DY R
Sbjct: 158 EESLGNRRIRVDVADQAQDKDRDDRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRR-- 215
Query: 381 RGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERERRQRERERERE- 439
++F +Y + YR+ R+ R+ +R+ +R RDR +R R+ +R +
Sbjct: 216 ---GDDSFGDKYRDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDS 272
Query: 440 ------------HERDKERQRRKEEWERERAKRDEKDRQHR-DRDREKEREKEKGKP--- 483
+ RD + + + +E +RD++ R D R+ R ++G P
Sbjct: 273 RIGSGRRAFGSGYRRDDDYRGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRP 332
Query: 484 ----KPRS-PQPPSRQAEPPKKEAATT----GPQVKRADEWKDPWRRSKSPKKKLGVSV- 533
KPRS P+ A + A + V A ++ R + ++KL +
Sbjct: 333 KLNLKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLD 392
Query: 534 SPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFS 593
P RR R+ S S R SR+ S S + S+ SSR++R
Sbjct: 393 EPKLERRPRERHPSWRSEETQERERSRTG---------SESSQTGTSTTSSRNARRRESE 443
Query: 594 GSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTT 653
S SPT P +P K PAPPP + VK+ + PPA Q++ T
Sbjct: 444 KSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKE--NAWVKRSSNPPARSQSSDTE 501
Query: 654 APVP----------EPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSY-------- 695
P +P++ G R+ K P + S G G G +
Sbjct: 502 QQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTGNSSRGPGDGGNRDHWKESDR 561
Query: 696 --------SGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSED 730
S S+ + + S SSA S +A SVD ED
Sbjct: 562 KDGKKDQDSRSAPEPKKPEENPASKFSSA--SKYAALSVDGED 602
Score = 58.9 bits (141), Expect = 2e-08
Identities = 92/426 (21%), Positives = 145/426 (34%), Gaps = 52/426 (12%)
Query: 462 EKDRQHRDRDREKEREKEKGKPKPRS-PQPPSRQAEPPKKEAATTGPQVKR---ADEWKD 517
+KDR R R++ R+ +K R+ P S PP++ + G + + +D ++D
Sbjct: 176 DKDRDDRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRYDSDRYRD 235
Query: 518 PWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSS 577
+R + + R R + S +S S R + GSG R
Sbjct: 236 GYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAF--GSGYRRDDDYRG 293
Query: 578 SYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSV 637
Y R R S S S P P RP + K P + +
Sbjct: 294 GGDRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGP-PQRPKLNLKPRSTPKEDDSSASTS 352
Query: 638 K-----------KPAPPPA---------PPQATKTTAPVPEPTKPGDPREARRKERPART 677
+ KP A + K + EP PRE R T
Sbjct: 353 QSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEET 412
Query: 678 PPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLAS 737
R R+ +GS S + + SS +R S S+ + T + ED ++ +
Sbjct: 413 QERERSRTGSESSQTGTSTTSSRNARRRE--SEKSLENETLNKE-------EDCHSPTSK 463
Query: 738 PVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTP 797
P PA KE K+ + D+ Q P S GGK + P+ P
Sbjct: 464 PPKPDQPLKVMPAPPPKENAWVKRSSNPPARSQSSDTEQQSPTSG----GGKVA--PAQP 517
Query: 798 QQAPPGQPQQGTFVAHKEIKLTLLNKA---ADKGSRKRYEPSDK-------DRQSPPPAK 847
+ PG+ + K N + D G+R ++ SD+ D +S P K
Sbjct: 518 SEEGPGRKDENKVDGMNAPKGQTGNSSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPK 577
Query: 848 RPNTSP 853
+P +P
Sbjct: 578 KPEENP 583
Score = 33.1 bits (74), Expect = 1.3
Identities = 67/332 (20%), Positives = 107/332 (32%), Gaps = 51/332 (15%)
Query: 2 DVAESPERDPHS-PEDEEQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQ 60
D A+ +RD S D + +D D +D D R D ++ R S
Sbjct: 172 DQAQDKDRDDRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRYDSD 231
Query: 61 EEEDNHSDE------------------EDRASEPKSQDQDSEVNELSRGPTSSPCEEEGD 102
D + D +DR S + DS + R S ++
Sbjct: 232 RYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDY 291
Query: 103 EGEEDRTSDL---RDEASSVTRELDEHELDY---DEEVPEEPAPAVQEDEAEKAGAEDDE 156
G DR D RD+ S +R+ D DY D P+ P ++ K EDD
Sbjct: 292 RGGGDRYEDRYDRRDDRSWSSRD-DYSRDDYRRDDRGPPQRPKLNLKPRSTPK---EDDS 347
Query: 157 EKGEGTPREE-----GKAGVQSVGEKESLEAAKEKKKEDDDGEIDDGEIDDDDLEEGEV- 210
G V + + +E +K++E ++D+ +++ E
Sbjct: 348 SASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSW 407
Query: 211 -KDPSDRKVRPRPTCRFFMKGNCTWGMNCRFIHPGVNDKGNYSLITKADPFPPNGAPPLG 269
+ + + R R G T N +L + D P PP
Sbjct: 408 RSEETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKP 467
Query: 270 PHPLMPANPWGGPVVDEILPPPPPEPPTESAW 301
PL +++P PPP E+AW
Sbjct: 468 DQPL------------KVMPAPPP---KENAW 484
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 84.3 bits (207), Expect = 5e-16
Identities = 130/536 (24%), Positives = 200/536 (37%), Gaps = 71/536 (13%)
Query: 456 ERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEW 515
+R++ D + +D+ ++++ +GK S +R PP + P A
Sbjct: 994 KRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSS--NRPFTPPTSTGGSKSPG--SAGRS 1049
Query: 516 KDPWRRSKSPKKKLGVSV--------SPSRARRRRKTSASSASASNSSRSSSRSSSYSGS 567
+ P + P K+ + + PS + + + S+S S S S S SSS S S
Sbjct: 1050 QTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSAS 1109
Query: 568 GSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPS-PTPSP------HRPSIR 620
S + +S S SS S SS S GS S+S +SS S P SP S
Sbjct: 1110 TSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSS 1169
Query: 621 TKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPR 680
TK +P P S+ KP P+ + + + P KP TPP
Sbjct: 1170 TKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKP-----------VPGTPPS 1218
Query: 681 RRTLSGSGSGSGSSY-SGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPV 739
+ S SGSG S+ SG+SS S S S + S S + + + S A +S
Sbjct: 1219 SKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPS----SNSCTASSSSFS 1274
Query: 740 SSASSRSPAPAQTRKEKGKSKKEDGVKE-----EKRKRDSSTQPPKSAKPPAG-----GK 789
SS SS S + Q KGKS + +K K T P P G
Sbjct: 1275 SSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTN 1334
Query: 790 SSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDK----------- 838
SS P + + G QG + K + + S K+ S
Sbjct: 1335 SSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIII 1394
Query: 839 ---DRQSPP-----PAKRPNTSPDRGSRDRKSGGR-LGSP-----KPERQRGQNSKAPAA 884
D SP ++P S G R + + + GSP P+ +RG S + +
Sbjct: 1395 SKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHS-KS 1453
Query: 885 PADRKRQLSPQSKSSSKVTSVPGKASDPGAASTKSGKASTLSRREELLKQLKAVED 940
PA + L +S+S S + + S + + + ++ K+ K V+D
Sbjct: 1454 PAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKHKKEKKKVKD 1509
Score = 66.2 bits (160), Expect = 1e-10
Identities = 93/398 (23%), Positives = 137/398 (34%), Gaps = 53/398 (13%)
Query: 541 RRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSR 600
+ KT + +S S+ RSR+ S+ S R + + +S S
Sbjct: 965 KEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSH 1024
Query: 601 SFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPT 660
S S+ P PT + S + G PPG V P P Q K T V +P+
Sbjct: 1025 SSSNRPFTPPTSTGGSKSPGSAGRSQTPPG------VATPPIPKITIQIPKGTVMVGKPS 1078
Query: 661 KPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSS 720
+ ++S SGS S S+S SSS S S S SS S +SSS
Sbjct: 1079 SHSQYTSS-------------GSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSS 1125
Query: 721 SSAHSV-DSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPP 779
+ S+ S+ S SS S P + K G S K + + + SS P
Sbjct: 1126 KLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKH-GLSSGSSSTKMKPQGKPSSLMNP 1184
Query: 780 KSAKPPAGGKSSQQP-STPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDK 838
+KP S+ P + + A P +P GT PS K
Sbjct: 1185 SLSKPNISPSHSRPPGGSDKLASPMKPVPGT------------------------PPSSK 1220
Query: 839 DRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKS 898
AK P +S GS + G S + P + S
Sbjct: 1221 -------AKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSF 1273
Query: 899 SSKVTSVPGKASDPGAASTKSGKASTLSRREELLKQLK 936
SS +S+ + G++ KS + ++ +LK
Sbjct: 1274 SSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLK 1311
Score = 43.1 bits (100), Expect = 0.001
Identities = 86/367 (23%), Positives = 131/367 (35%), Gaps = 55/367 (14%)
Query: 478 KEKGKPKPRSPQPPS-RQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPS 536
K K + KP S PS + + G K A K S K K +S S S
Sbjct: 1171 KMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPIS-SGS 1229
Query: 537 RARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSY--SSYSSRSSRHSSFSG 594
TS+SS S+S SS S S SS S + SSS SS SS SS +
Sbjct: 1230 GGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGS 1289
Query: 595 SRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPP--GKAG------------------- 633
S+ +S S + PS + + + T G P G+ G
Sbjct: 1290 SKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGG 1349
Query: 634 ------EKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREAR----RKERPARTPPRRRT 683
EKS K + + ++ E G A+ + + + + + T
Sbjct: 1350 EFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVT 1409
Query: 684 LSGSGSGSGSSYSGSSSRSRSLSVSSVSSVS------SATSSSSSAHSVDSEDMYADLAS 737
L G SG + S++ +S + S + S S A++ + D ++ S
Sbjct: 1410 LQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGS 1469
Query: 738 PVSSASSRS---------PAP---AQTRKEKGKSKKEDGVKEEKRKRDSSTQPPK--SAK 783
++ S ++ P P + K+ K KK+ K+ R RD K S K
Sbjct: 1470 SIAEKSYQNSPSSDDGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIK 1529
Query: 784 PPAGGKS 790
P + KS
Sbjct: 1530 PESWSKS 1536
Score = 38.5 bits (88), Expect = 0.030
Identities = 56/244 (22%), Positives = 92/244 (37%), Gaps = 26/244 (10%)
Query: 687 SGSGSGSSYSGSSSRS-RSLSVSSVSSVSSATS--SSSSAHSVD----SEDMYADLASPV 739
S SG + G +S++ +L V + + T ++ A +VD S A + +
Sbjct: 887 SQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADL 946
Query: 740 SSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQ 799
S S P T + GK K + VKE +S+ P P GK S+ PS +
Sbjct: 947 MEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKP--GKRSRTPSNDGK 1004
Query: 800 APPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRD 859
+ P++ K AD + S +PP + + SP R
Sbjct: 1005 SKDKPPKR---------------KKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRS 1049
Query: 860 RKSGGRLGSPKPE--RQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGKASDPGAAST 917
+ G P P+ Q + + P+ + S S SSS S +S ++++
Sbjct: 1050 QTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSAS 1109
Query: 918 KSGK 921
SGK
Sbjct: 1110 TSGK 1113
Score = 35.4 bits (80), Expect = 0.26
Identities = 15/47 (31%), Positives = 31/47 (65%), Gaps = 1/47 (2%)
Query: 452 EWERERAKRDEKDRQH-RDRDREKEREKEKGKPKPRSPQPPSRQAEP 497
E+ E+ K+ +K+++ +D+DR+++R+K++ K K S +P S P
Sbjct: 1491 EYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSP 1537
Score = 33.5 bits (75), Expect = 0.97
Identities = 21/57 (36%), Positives = 33/57 (57%), Gaps = 11/57 (19%)
Query: 439 EHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKG---KPKPRSPQPPS 492
E+ +K ++ +KE K+ KD+ RDRDR+K+R+K+K KP+ S P S
Sbjct: 1491 EYSTEKHKKHKKE-------KKKVKDKD-RDRDRDKDRDKKKSHSIKPESWSKSPIS 1539
Score = 31.2 bits (69), Expect = 4.8
Identities = 13/78 (16%), Positives = 35/78 (44%), Gaps = 11/78 (14%)
Query: 385 YENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERERRQREREREREHERDK 444
Y+N P Y + ++ ++ +++ ++++R+RDR+++R ++ K
Sbjct: 1476 YQNSPSSDDGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDR-----------DKKK 1524
Query: 445 ERQRRKEEWERERAKRDE 462
+ E W + D+
Sbjct: 1525 SHSIKPESWSKSPISSDQ 1542
Score = 30.8 bits (68), Expect = 6.3
Identities = 13/60 (21%), Positives = 33/60 (55%)
Query: 454 ERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRAD 513
+ ++ K+++K + +DRDR+++++++K K P+ S+ + + T + AD
Sbjct: 1496 KHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQSLSMTSNTILSAD 1555
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 83.6 bits (205), Expect = 8e-16
Identities = 66/232 (28%), Positives = 110/232 (47%), Gaps = 44/232 (18%)
Query: 289 PPPPPEPPT-----ESAWERGLRHA-----KEVLKKATIRKEQEPDFE------------ 326
PPPP +PP + ER +R +E+ ++ R E+E D +
Sbjct: 1121 PPPPVQPPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRS 1180
Query: 327 -EKRFTVTIGEDEREFDKENEVFRDWNSRIPRDV-RDTVLEP--YADPYYDYEIERFWRG 382
++R E++ +K+ + + +++ D+ R T P Y P D +I
Sbjct: 1181 RDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQI------ 1234
Query: 383 GQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERER-RQREREREREHE 441
+ E R +ERE+ R+ ++ E ++ERE++ ERER RQ ERE+ REH
Sbjct: 1235 ----------VQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHS 1284
Query: 442 RDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSR 493
R+++R+R +E ER+R RD + R+R RE++R K + RS P R
Sbjct: 1285 RERDRERERER-ERDRGDRDRDRERDRERGRERDRRDTKRHSRSRSRSTPVR 1335
Score = 78.6 bits (192), Expect = 3e-14
Identities = 135/595 (22%), Positives = 210/595 (35%), Gaps = 88/595 (14%)
Query: 318 RKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVRDTVLEPYADPYYDYEIE 377
R E E R + +I E++ + D E + S R R L + P + E +
Sbjct: 193 RPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQ 252
Query: 378 RFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRER---------- 427
N RV+ E E E E ++ + E + E ++ RE
Sbjct: 253 ET----PSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEG 308
Query: 428 ERRQREREREREHERDKERQRRKEEWER--------ERAKRDEKDRQHRDRD-------R 472
E R + E ER K R + +E ER E A++ RQ ++++
Sbjct: 309 EEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLE 368
Query: 473 EKEREKEKG---KPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKL 529
E+ERE + K K +SP PP R E KK + P+ ++E P +K
Sbjct: 369 EEEREIKSSQGLKEKSKSPSPP-RLTEDRKKASLVALPEQTASEEETPPPLLTK------ 421
Query: 530 GVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRH 589
ASS S G S + +R
Sbjct: 422 ---------------EASSPPPHPQLHSEEEIEPMEGPAPPVLIQLSPPNTDADTRELLV 466
Query: 590 SSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQA 649
S + S SSPS + SP P + S +K P + A
Sbjct: 467 SQHTVQLVGGLSPLSSPSDTKAESPAEKVPEESVLPLVQKSTLADYSAQKDLEPESDRSA 526
Query: 650 TKTTAPVPEPT-----------KPG-DPREARRKERPARTPPRRRTLSGSGSGSGSSYSG 697
+ E +P + +E RR R + + S S SS S
Sbjct: 527 QPLPLKIEELALAKGITEECLKQPSLEQKEGRRASHTLLPSHRLKQSADSSSSRSSSSSS 586
Query: 698 SSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPV----SSASSRSPAPAQTR 753
SSSRSRS S S S S + S + P S++ SRS + +++R
Sbjct: 587 SSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMGSRSTSESRSRSRSRSR 646
Query: 754 KEKGKSKK--EDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFV 811
S+K GV RDSST ++ K P+ G+ P P Q +P++ T
Sbjct: 647 SASSNSRKSLSPGV-----SRDSSTSYTET-KDPSSGQEVATPPVP-QLQVCEPKERTST 699
Query: 812 AHKEIKLTLLN--KAADKGSRKRYEPS-------DKDRQSPPPAKRPNTSPDRGS 857
+ ++ L+ ++A+K +R +P + + PP A +P TS + S
Sbjct: 700 SSSSVQARRLSQPESAEKHVTQRLQPERGSPKKCEAEEAEPPAATQPQTSETQTS 754
Score = 66.2 bits (160), Expect = 1e-10
Identities = 58/213 (27%), Positives = 93/213 (43%), Gaps = 14/213 (6%)
Query: 396 EPYHNYRERERERERENRQRERERERERDR-ERERRQREREREREHERDKERQRRKEEWE 454
+P + R +RE+ER R++ ERERE +R ER R +RE +R++ E + R R ++
Sbjct: 1126 QPPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRR 1185
Query: 455 RERAKRDEKDRQHRDRDREKEREK------EKGKPKPRSPQPPSRQAEPPKKEAATTGPQ 508
+ERAK EK + +++ +E+ K K K P P ++ +KEA +
Sbjct: 1186 KERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEA----ER 1241
Query: 509 VKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSG 568
+RA E + RR + +++ + R R+ + R R
Sbjct: 1242 AERAKEREK--RRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDR 1299
Query: 569 SSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRS 601
R R R R R + SRSRSRS
Sbjct: 1300 GDRDRDRERDRERGRERDRRDTK-RHSRSRSRS 1331
Score = 63.5 bits (153), Expect = 9e-10
Identities = 132/630 (20%), Positives = 227/630 (36%), Gaps = 101/630 (16%)
Query: 6 SPERDPHSPEDEEQPQGLSD-DDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQEEED 64
S + H PE E + + +++ D+ ++ + + D+ S P ED
Sbjct: 749 SETQTSHLPESERIHHTVEEKEEVTMDTSENRPENDVPEPPMPIADQVSNDDRPEGSVED 808
Query: 65 NHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDE-------GEEDRTSDLRDEAS 117
+E+ +S PKS + V ++G + + EG + G T+ + S
Sbjct: 809 ---EEKKESSLPKSFKRKISVVSATKGVPAGNSDTEGGQPGRKRRWGASTATTQKKPSIS 865
Query: 118 SVTREL-----DEHELDYDEEVPEEPAP--AVQEDEAEKAGAEDDEEKGEGTPREEGKAG 170
T L D L E V + A + EDE E+ G + +KG R
Sbjct: 866 ITTESLKSLIPDIKPLAGQEAVVDLHADDSRISEDETERNGDDGTHDKGLKICRT----- 920
Query: 171 VQSVGEKESLEAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKG 230
V V E E + +++E++ + + E + P++ +V+ G
Sbjct: 921 VTQVVPAEGQENGQREEEEEEKEPEAEPPVPPQVSVEVALPPPAEHEVKK------VTLG 974
Query: 231 NCTWGMNCRFIHPGVNDKGNYSLITKADPFPPNGAPPLGPHPLMPANPWGGPVVDEILPP 290
+ + GV+ + + T P PP G H P+ + E+L
Sbjct: 975 DTLTRRSISQQKSGVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGR 1034
Query: 291 PPPEPPTESAWERGLRH---------AKEVLKKATIRKEQEPDFEEKRFTVTIGE-DERE 340
E+ W ++ + V + + + P K E DE +
Sbjct: 1035 TGTLVE-EAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELD 1093
Query: 341 FDKENEVFRDWNSR-----IPRDVRDTVLEPYADPYYDYEIERFWRGGQYENFRVQYTET 395
+ + V R ++ IPR + P P + +R Q R Q+ E
Sbjct: 1094 YHRGLLVDRPSETKTEEQGIPRPLHPPPPPPVQPPQHPRAEQR----EQERAVREQWAER 1149
Query: 396 EPYHNYRERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKE---- 451
E RER R +R + RE R R R R+RR++ER + +E + +K+ + ++E
Sbjct: 1150 EREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAK 1209
Query: 452 ----------------------------EWER-ERAKRDEKDRQHRDRDREKEREKEKGK 482
E ER ERAK EK R+ ++ + +KEREKE +
Sbjct: 1210 LLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAER 1269
Query: 483 PKPRSPQPPSRQAEPPKKEAATTGPQVK-RADEWKDPWRRSKSPKKKLGVSVSPSRARRR 541
+ R + R+ +++ + + R D +D R + R R R
Sbjct: 1270 ERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRER-----------GRERDR 1318
Query: 542 RKTSASSASASNSSRSSSRSSSYSGSGSSR 571
R T SRS SRS+ G R
Sbjct: 1319 RDTK-------RHSRSRSRSTPVRDRGGRR 1341
Score = 57.4 bits (137), Expect = 6e-08
Identities = 105/530 (19%), Positives = 194/530 (36%), Gaps = 56/530 (10%)
Query: 409 ERENRQRERERERERDRERERRQR-----EREREREHERDKERQRRKEEWERERAKRDEK 463
E+ + E+ R+ ER R R+ R E + E E D+E R R RA R+ K
Sbjct: 212 EKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRN---LRVRADRNLK 268
Query: 464 DRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSK 523
+ + + E+E + E+ + + SR+A P KE G ++ R + R K
Sbjct: 269 TEEEEEEEEEEEEDDEEEEGDDEGQK--SREA-PILKEFKEEGEEIPRVKPEEMMDERPK 325
Query: 524 SPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYS 583
+ ++ V R R ++ + S A +++ S +SS
Sbjct: 326 TRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTT--SPLEEEEREIKSSQGLKEK 383
Query: 584 SRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPP-GKAGEKSVKKPAP 642
S+S + R ++ S + P + + P + TK +PPP + + +P
Sbjct: 384 SKSPSPPRLTEDRKKA-SLVALPEQTASEEETPPPLLTKEASSPPPHPQLHSEEEIEPME 442
Query: 643 PPAPPQATKTTAP----------VPEPT-------KPGDPREARRKERPARTPPRRRTLS 685
PAPP + + P V + T P + E PA P L
Sbjct: 443 GPAPPVLIQLSPPNTDADTRELLVSQHTVQLVGGLSPLSSPSDTKAESPAEKVPEESVLP 502
Query: 686 GSGSGSGSSYSGS---------SSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLA 736
+ + YS S++ L + ++ T S++ ++ A
Sbjct: 503 LVQKSTLADYSAQKDLEPESDRSAQPLPLKIEELALAKGITEECLKQPSLEQKE--GRRA 560
Query: 737 SPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPST 796
S S R A + + S + R DSS +S P + +
Sbjct: 561 SHTLLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGS--RSHSPLRSKQRDVAQAR 618
Query: 797 PQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRG 856
P G+P+ G+ + T +++ + SR R S+ + P R +++
Sbjct: 619 THANPRGRPKMGS-------RSTSESRSRSR-SRSRSASSNSRKSLSPGVSRDSSTSYTE 670
Query: 857 SRDRKSGGRLGSPK-PERQ--RGQNSKAPAAPADRKRQLSPQSKSSSKVT 903
++D SG + +P P+ Q + + ++ + + R+LS + VT
Sbjct: 671 TKDPSSGQEVATPPVPQLQVCEPKERTSTSSSSVQARRLSQPESAEKHVT 720
Score = 56.6 bits (135), Expect = 1e-07
Identities = 77/306 (25%), Positives = 111/306 (36%), Gaps = 43/306 (14%)
Query: 532 SVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRS----- 586
S+ RR T S S+ SSS SS S S SSRSRSRS S S S
Sbjct: 551 SLEQKEGRRASHTLLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSK 610
Query: 587 ----------------------SRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGE 624
S S S SRSRSRS SS+ S +P R S + E
Sbjct: 611 QRDVAQARTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTE 670
Query: 625 PAPPPGKAGEKSVKKPAPP---PAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRR 681
P +G++ P P P + T T++ + + P E+ K R P R
Sbjct: 671 TKDP--SSGQEVATPPVPQLQVCEPKERTSTSSSSVQARRLSQP-ESAEKHVTQRLQPER 727
Query: 682 RTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSS 741
GS + + + +S + S S H+V+ ++ S
Sbjct: 728 ------GSPKKCEAEEAEPPAATQPQTSETQTSHLPESERIHHTVEEKEEVTMDTSENRP 781
Query: 742 ASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQ--PSTPQQ 799
+ P + + +G E++ K++SS PKS K S+ + P+
Sbjct: 782 ENDVPEPPMPIADQVSNDDRPEGSVEDEEKKESSL--PKSFKRKISVVSATKGVPAGNSD 839
Query: 800 APPGQP 805
GQP
Sbjct: 840 TEGGQP 845
Score = 53.1 bits (126), Expect = 1e-06
Identities = 170/876 (19%), Positives = 306/876 (34%), Gaps = 118/876 (13%)
Query: 8 ERDPHSPEDEEQPQGLSDDDILRDSGSDQDLDG---AGVRASDLEDEESAARGPSQ--EE 62
ER+ + E+ S+D+++ G L + + +LE + R S EE
Sbjct: 153 EREAREAAELEEASAESEDEMIHPEGVASLLPPDFQSSLERPELELSRHSPRKSSSISEE 212
Query: 63 EDNHSDEEDRASEPKSQD-QDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVTR 121
+ + DE+ R E +S + + +LS G S P EEE D+ R +R + + T
Sbjct: 213 KGDSDDEKPRKGERRSSRVRQARAAKLSEG--SQPAEEEEDQETPSRNLRVRADRNLKTE 270
Query: 122 ELDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTP----------REEGKAGV 171
E +E E + +E+ EE + E ++ +E+GE P R + ++
Sbjct: 271 EEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQE 330
Query: 172 QSVGEK-----ESLEAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPR-PTCR 225
Q V E+ S E A++ E + + EE E+K K + + P+
Sbjct: 331 QEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPP 390
Query: 226 FFMKGNCTWGMNCRFIHPGVNDKGNYSLITKADPFPPNGAPPLGPHPLMPA----NPWGG 281
+ + ++ L+TK PP PHP + + P G
Sbjct: 391 RLTEDRKKASLVALPEQTASEEETPPPLLTKEASSPP-------PHPQLHSEEEIEPMEG 443
Query: 282 PVVDEILPPPPPEPPTESAWERGLRHAKEV------LKKATIRKEQEPDFEEKRFTV--- 332
P ++ PP ++ +H ++ L + K + P + +V
Sbjct: 444 PAPPVLIQLSPPNTDADTRELLVSQHTVQLVGGLSPLSSPSDTKAESPAEKVPEESVLPL 503
Query: 333 ----TIGEDEREFDKENEVFRDWNSRIPRDVRDTVL------EPYADPYYDYEIERFWRG 382
T+ + + D E E R +P + + L E P +
Sbjct: 504 VQKSTLADYSAQKDLEPESDRS-AQPLPLKIEELALAKGITEECLKQPSLE--------- 553
Query: 383 GQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERERR-QREREREREHE 441
Q E R +T P H ++ + R R R + R R +
Sbjct: 554 -QKEGRRASHT-LLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQ 611
Query: 442 RDKERQRRKEEWERERAKRDEKD-RQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKK 500
RD Q R R R K + + R R R + R K SP SR +
Sbjct: 612 RD-VAQARTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSLSP-GVSRDSSTSYT 669
Query: 501 EA--ATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASAS---NSS 555
E ++G +V P + PK++ S S +ARR + ++ +
Sbjct: 670 ETKDPSSGQEVATPPV---PQLQVCEPKERTSTSSSSVQARRLSQPESAEKHVTQRLQPE 726
Query: 556 RSSSR--SSSYSGSGSSRSRSRSSSYSSYSSRSSR-HSSFSGSRSRSRSFSSSPSPSPTP 612
R S + + + ++ S + +S+ S R H + + S + + P
Sbjct: 727 RGSPKKCEAEEAEPPAATQPQTSETQTSHLPESERIHHTVEEKEEVTMDTSENRPENDVP 786
Query: 613 SPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKE 672
P P P G ++ K+ + P++ K V TK G P A +
Sbjct: 787 EPPMPIADQVSNDDRPEGSVEDEEKKE----SSLPKSFKRKISVVSATK-GVP--AGNSD 839
Query: 673 RPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMY 732
P R+R S + ++ + S+S+++ S S A D++
Sbjct: 840 TEGGQPGRKRRWGAS--------TATTQKKPSISITTESLKSLIPDIKPLAGQEAVVDLH 891
Query: 733 ADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRK--RDSSTQPPKSAKPPAGGKS 790
AD ++ +++ + +DG ++ K R + P + +
Sbjct: 892 AD--------------DSRISEDETERNGDDGTHDKGLKICRTVTQVVPAEGQENGQREE 937
Query: 791 SQQPSTPQQAPPGQPQQGTFVA------HKEIKLTL 820
++ P+ PP PQ VA H+ K+TL
Sbjct: 938 EEEEKEPEAEPPVPPQVSVEVALPPPAEHEVKKVTL 973
Score = 43.1 bits (100), Expect = 0.001
Identities = 92/434 (21%), Positives = 149/434 (34%), Gaps = 68/434 (15%)
Query: 473 EKEREKEKGKPKPRSPQPPSRQAE---PPKKEAATTGPQVKRADEWKDPWRRSKSPKKKL 529
++E E+E+ +P+ P PP E PP E +VK+ RRS S +K
Sbjct: 934 QREEEEEEKEPEAEPPVPPQVSVEVALPPPAEH-----EVKKVTLGDTLTRRSISQQKS- 987
Query: 530 GVSVS-PSRARRRRKTSASSASASNSSRSSS---------------RSSSYSGSGSSRSR 573
GVS++ R + S SN S+ R+ + +
Sbjct: 988 GVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDK 1047
Query: 574 SRSSSYSSYSS-------RSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPA 626
+S + +YS+ R++ H +S + + + HR + +
Sbjct: 1048 IKSHCFVTYSTVEEAVATRTALHG-VKWPQSNPKFLCADYAEQDELDYHRGLLVDR---- 1102
Query: 627 PPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKP-GDPREARR------KERPARTPP 679
P K E+ + +P PP PP PV P P + RE R ER
Sbjct: 1103 PSETKTEEQGIPRPLHPPPPP-------PVQPPQHPRAEQREQERAVREQWAEREREMER 1155
Query: 680 RRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSE---DMYADLA 736
R RT S G SRSRS S S E + DL
Sbjct: 1156 RERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLF 1215
Query: 737 SPVSSASSRSPAPAQTRK--EKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQP 794
+A P + +K + E + EKR+++ + K + A + ++Q
Sbjct: 1216 RKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQL 1275
Query: 795 STPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDR---QSPPPAKRPNT 851
++ + + +E D+G R R D++R + KR +
Sbjct: 1276 EREKRREHSRERDRERERERE---------RDRGDRDRDRERDRERGRERDRRDTKRHSR 1326
Query: 852 SPDRGSRDRKSGGR 865
S R + R GGR
Sbjct: 1327 SRSRSTPVRDRGGR 1340
Score = 33.1 bits (74), Expect = 1.3
Identities = 105/580 (18%), Positives = 196/580 (33%), Gaps = 54/580 (9%)
Query: 407 ERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQ 466
+ R ++ E+ + + ER ++ E E Q + E + E+
Sbjct: 705 QARRLSQPESAEKHVTQRLQPERGSPKKCEAEEAEPPAATQPQTSETQTSHLPESERIHH 764
Query: 467 HRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPK 526
+ E + + +P+ P+PP A+ + P+ DE K KS K
Sbjct: 765 TVEEKEEVTMDTSENRPENDVPEPPMPIADQVSNDDR---PEGSVEDEEKKESSLPKSFK 821
Query: 527 KKLGVSVSPSRARRRRKTSASSASASNSSR--SSSRSSSYSGSGSSRSRSRSSSYSSYSS 584
+K+ V VS ++ + R +S+ ++ S S + S S
Sbjct: 822 RKISV-VSATKGVPAGNSDTEGGQPGRKRRWGASTATTQKKPSISITTESLKSLIPDIKP 880
Query: 585 RSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSI---RTKGEPAPPPGKAG-----EKS 636
+ + + SR + H + RT + P G+ E+
Sbjct: 881 LAGQEAVVDLHADDSRISEDETERNGDDGTHDKGLKICRTVTQVVPAEGQENGQREEEEE 940
Query: 637 VKKP-APPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSG--- 692
K+P A PP PPQ + A P P E K+ RR++S SG
Sbjct: 941 EKEPEAEPPVPPQVSVEVALPP-------PAEHEVKKVTLGDTLTRRSISQQKSGVSITI 993
Query: 693 -----SSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSP 747
++ S R + ++ +S++ + + + A + S
Sbjct: 994 DDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDKIKSHCF 1053
Query: 748 APAQTRKEKGKSKKE-DGVK-----------------EEKRKRDSSTQPPKSAKPPAGGK 789
T +E ++ GVK E R P K G
Sbjct: 1054 VTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHRGLLVDRPSETKTEEQG- 1112
Query: 790 SSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADK-GSRKRYEPSDKDRQSPPPAKR 848
+P P PP QP Q +E + + + A++ +R E + +R+ R
Sbjct: 1113 -IPRPLHPPPPPPVQPPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVR 1171
Query: 849 PNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGK 908
SRDR+ R S + + ++ + ++ PA L ++K++ + +P
Sbjct: 1172 EGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQ-EEPPAKLLDDLFRKTKAAPCIYWLP-- 1228
Query: 909 ASDPGAASTKSGKASTLSRREELLKQLKAVEDAIARKRAK 948
+D ++ +A RE+ K+ + E K A+
Sbjct: 1229 LTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAE 1268
Score = 30.4 bits (67), Expect = 8.2
Identities = 24/113 (21%), Positives = 48/113 (42%), Gaps = 2/113 (1%)
Query: 4 AESPERDPHSPED-EEQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQEE 62
A+S E+ E +E+P DD+ R + + + + S + +E+ ++E
Sbjct: 1189 AKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKER 1248
Query: 63 EDNHSDEEDRASEPKSQDQDSEVN-ELSRGPTSSPCEEEGDEGEEDRTSDLRD 114
E ++E+ + + ++ + E N +L R E E E +R D D
Sbjct: 1249 EKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGD 1301
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.303 0.123 0.348
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,602,158
Number of Sequences: 37866
Number of extensions: 3418395
Number of successful extensions: 110695
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1566
Number of HSP's successfully gapped in prelim test: 2860
Number of HSP's that attempted gapping in prelim test: 24513
Number of HSP's gapped (non-prelim): 40548
length of query: 953
length of database: 18,247,518
effective HSP length: 112
effective length of query: 841
effective length of database: 14,006,526
effective search space: 11779488366
effective search space used: 11779488366
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.