Guide to the Human Genome
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Search of human proteins with 31083236

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31083236 gamma isoform of regulatory subunit B56, protein
phosphatase 2A isoform b [Homo sapiens]
         (485 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31083236 gamma isoform of regulatory subunit B56, protein pho...   985   0.0  
gi|31083259 gamma isoform of regulatory subunit B56, protein pho...   966   0.0  
gi|240849359 gamma isoform of regulatory subunit B56, protein ph...   926   0.0  
gi|240849353 gamma isoform of regulatory subunit B56, protein ph...   906   0.0  
gi|31083243 gamma isoform of regulatory subunit B56, protein pho...   899   0.0  
gi|5453954 delta isoform of regulatory subunit B56, protein phos...   782   0.0  
gi|31083280 delta isoform of regulatory subunit B56, protein pho...   776   0.0  
gi|31083288 delta isoform of regulatory subunit B56, protein pho...   775   0.0  
gi|5453956 epsilon isoform of regulatory subunit B56, protein ph...   615   e-176
gi|5453950 protein phosphatase 2, regulatory subunit B (B56), al...   609   e-174
gi|5453952 beta isoform of regulatory subunit B56, protein phosp...   593   e-169
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s...    34   0.34 
gi|4505727 peroxisomal biogenesis factor 3 [Homo sapiens]              34   0.34 
gi|148746195 trichohyalin [Homo sapiens]                               32   1.3  
gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo...    32   1.3  
gi|254039614 coiled-coil domain containing 120 isoform 4 [Homo s...    32   1.7  
gi|254039612 coiled-coil domain containing 120 isoform 2 [Homo s...    32   1.7  
gi|5453974 protein kinase N2 [Homo sapiens]                            32   1.7  
gi|222080092 WD repeat domain 91 [Homo sapiens]                        31   2.2  
gi|110611228 utrophin [Homo sapiens]                                   30   3.8  
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo...    30   3.8  
gi|194294523 intersectin 2 isoform 3 [Homo sapiens]                    30   4.9  
gi|194294521 intersectin 2 isoform 1 [Homo sapiens]                    30   4.9  
gi|194294525 intersectin 2 isoform 2 [Homo sapiens]                    30   4.9  
gi|163792208 Rho guanine exchange factor 16 [Homo sapiens]             30   4.9  
gi|167614488 TBC1 domain family, member 10B [Homo sapiens]             30   6.4  
gi|154350213 hypothetical protein LOC79591 [Homo sapiens]              30   6.4  
gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]           29   8.4  
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    29   8.4  
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho...    29   8.4  

>gi|31083236 gamma isoform of regulatory subunit B56, protein
           phosphatase 2A isoform b [Homo sapiens]
          Length = 485

 Score =  985 bits (2547), Expect = 0.0
 Identities = 485/485 (100%), Positives = 485/485 (100%)

Query: 1   MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL 60
           MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL
Sbjct: 1   MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL 60

Query: 61  SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP 120
           SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP
Sbjct: 61  SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP 120

Query: 121 EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD 180
           EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD
Sbjct: 121 EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD 180

Query: 181 FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK 240
           FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK
Sbjct: 181 FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK 240

Query: 241 EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK 300
           EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK
Sbjct: 241 EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK 300

Query: 301 EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS 360
           EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS
Sbjct: 301 EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS 360

Query: 361 DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK 420
           DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK
Sbjct: 361 DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK 420

Query: 421 LKMKEREEAWVKIENLAKANPQAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELA 480
           LKMKEREEAWVKIENLAKANPQAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELA
Sbjct: 421 LKMKEREEAWVKIENLAKANPQAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELA 480

Query: 481 SQDGR 485
           SQDGR
Sbjct: 481 SQDGR 485


>gi|31083259 gamma isoform of regulatory subunit B56, protein
           phosphatase 2A isoform a [Homo sapiens]
          Length = 524

 Score =  966 bits (2497), Expect = 0.0
 Identities = 485/524 (92%), Positives = 485/524 (92%), Gaps = 39/524 (7%)

Query: 1   MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL 60
           MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL
Sbjct: 1   MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL 60

Query: 61  SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP 120
           SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP
Sbjct: 61  SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP 120

Query: 121 EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD 180
           EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD
Sbjct: 121 EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD 180

Query: 181 FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK 240
           FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK
Sbjct: 181 FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK 240

Query: 241 EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK 300
           EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK
Sbjct: 241 EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK 300

Query: 301 EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS 360
           EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS
Sbjct: 301 EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS 360

Query: 361 DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK 420
           DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK
Sbjct: 361 DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK 420

Query: 421 LKMKEREEAWVKIENLAKANP--------------------------------------- 441
           LKMKEREEAWVKIENLAKANP                                       
Sbjct: 421 LKMKEREEAWVKIENLAKANPQYTVYSQASTMSIPVAMETDGPLFEDVQMLRKTVKDEAH 480

Query: 442 QAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELASQDGR 485
           QAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELASQDGR
Sbjct: 481 QAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELASQDGR 524


>gi|240849359 gamma isoform of regulatory subunit B56, protein
           phosphatase 2A isoform f [Homo sapiens]
          Length = 540

 Score =  926 bits (2392), Expect = 0.0
 Identities = 458/471 (97%), Positives = 463/471 (98%), Gaps = 2/471 (0%)

Query: 15  AANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALS 74
           +A++N   Q   L  ++DVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALS
Sbjct: 72  SASNNRELQK--LPSLKDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALS 129

Query: 75  EMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHL 134
           EMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHL
Sbjct: 130 EMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHL 189

Query: 135 QLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFL 194
           QLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFL
Sbjct: 190 QLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFL 249

Query: 195 GLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPL 254
           GLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPL
Sbjct: 250 GLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPL 309

Query: 255 HKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDV 314
           HKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDV
Sbjct: 310 HKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDV 369

Query: 315 IEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSL 374
           IEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSL
Sbjct: 370 IEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSL 429

Query: 375 YRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIE 434
           YRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIE
Sbjct: 430 YRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIE 489

Query: 435 NLAKANPQAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELASQDGR 485
           NLAKANPQAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELASQDGR
Sbjct: 490 NLAKANPQAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELASQDGR 540


>gi|240849353 gamma isoform of regulatory subunit B56, protein
           phosphatase 2A isoform e [Homo sapiens]
          Length = 555

 Score =  906 bits (2342), Expect = 0.0
 Identities = 455/494 (92%), Positives = 455/494 (92%), Gaps = 39/494 (7%)

Query: 31  RDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEP 90
           RDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEP
Sbjct: 62  RDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEP 121

Query: 91  IYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDF 150
           IYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDF
Sbjct: 122 IYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDF 181

Query: 151 QPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYR 210
           QPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYR
Sbjct: 182 QPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYR 241

Query: 211 FIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYC 270
           FIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYC
Sbjct: 242 FIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYC 301

Query: 271 VVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQ 330
           VVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQ
Sbjct: 302 VVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQ 361

Query: 331 LAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLI 390
           LAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLI
Sbjct: 362 LAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLI 421

Query: 391 YNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANP--------- 441
           YNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANP         
Sbjct: 422 YNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVYSQAS 481

Query: 442 ------------------------------QAQKDPKKDRPLARRKSELPQDPHTKKALE 471
                                         QAQKDPKKDRPLARRKSELPQDPHTKKALE
Sbjct: 482 TMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSELPQDPHTKKALE 541

Query: 472 AHCRADELASQDGR 485
           AHCRADELASQDGR
Sbjct: 542 AHCRADELASQDGR 555


>gi|31083243 gamma isoform of regulatory subunit B56, protein
           phosphatase 2A isoform c [Homo sapiens]
          Length = 449

 Score =  899 bits (2323), Expect = 0.0
 Identities = 443/445 (99%), Positives = 443/445 (99%)

Query: 1   MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL 60
           MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL
Sbjct: 1   MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL 60

Query: 61  SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP 120
           SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP
Sbjct: 61  SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP 120

Query: 121 EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD 180
           EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD
Sbjct: 121 EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD 180

Query: 181 FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK 240
           FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK
Sbjct: 181 FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK 240

Query: 241 EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK 300
           EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK
Sbjct: 241 EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK 300

Query: 301 EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS 360
           EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS
Sbjct: 301 EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS 360

Query: 361 DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK 420
           DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK
Sbjct: 361 DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK 420

Query: 421 LKMKEREEAWVKIENLAKANPQAQK 445
           LKMKEREEAWVKIENLAKANPQ  K
Sbjct: 421 LKMKEREEAWVKIENLAKANPQVLK 445


>gi|5453954 delta isoform of regulatory subunit B56, protein
           phosphatase 2A isoform 1 [Homo sapiens]
          Length = 602

 Score =  782 bits (2019), Expect = 0.0
 Identities = 390/495 (78%), Positives = 427/495 (86%), Gaps = 41/495 (8%)

Query: 30  IRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITE 89
           ++D P  ++E+LFIQKLRQCCVLFDFVSDPLSDLK+KEVKRA L+EMVEYITH+R+V+TE
Sbjct: 106 LKDSPTQEREELFIQKLRQCCVLFDFVSDPLSDLKFKEVKRAGLNEMVEYITHSRDVVTE 165

Query: 90  PIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPD 149
            IYPE V MF+VN+FRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPD
Sbjct: 166 AIYPEAVTMFSVNLFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPD 225

Query: 150 FQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFY 209
           FQPNIAKKYIDQKFVL LL+LFDSEDPRERDFLKT LHRIYGKFLGLRAYIR+QIN+IFY
Sbjct: 226 FQPNIAKKYIDQKFVLALLDLFDSEDPRERDFLKTILHRIYGKFLGLRAYIRRQINHIFY 285

Query: 210 RFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAY 269
           RFIYETEHHNGIAELLEILGSIINGFALPLKEEHK+FL++VLLPLHKVKSLSVYHPQLAY
Sbjct: 286 RFIYETEHHNGIAELLEILGSIINGFALPLKEEHKMFLIRVLLPLHKVKSLSVYHPQLAY 345

Query: 270 CVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFR 329
           CVVQFLEK+S+LTEPV++ LLK+WPKTHSPKEVMFLNELEEILDVIEPSEF K+MEPLFR
Sbjct: 346 CVVQFLEKESSLTEPVIVGLLKFWPKTHSPKEVMFLNELEEILDVIEPSEFSKVMEPLFR 405

Query: 330 QLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGL 389
           QLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAA++LPIMFP+LYRNSK+HWNKTIHGL
Sbjct: 406 QLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAARVLPIMFPALYRNSKSHWNKTIHGL 465

Query: 390 IYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANP-------- 441
           IYNALKLFMEMNQKLFDDCTQQ+KAEK K + +MKEREE W KIE LA+ NP        
Sbjct: 466 IYNALKLFMEMNQKLFDDCTQQYKAEKQKGRFRMKEREEMWQKIEELARLNPQYPMFRAP 525

Query: 442 -------------------------------QAQKDPKKDRPLARRKSELPQDPHTKKAL 470
                                          Q  KD KK++ L RRKSELPQD +T KAL
Sbjct: 526 PPLPPVYSMETETPTAEDIQLLKRTVETEAVQMLKDIKKEKVLLRRKSELPQDVYTIKAL 585

Query: 471 EAHCRADEL--ASQD 483
           EAH RA+E   ASQ+
Sbjct: 586 EAHKRAEEFLTASQE 600


>gi|31083280 delta isoform of regulatory subunit B56, protein
           phosphatase 2A isoform 2 [Homo sapiens]
          Length = 570

 Score =  776 bits (2004), Expect = 0.0
 Identities = 391/509 (76%), Positives = 429/509 (84%), Gaps = 41/509 (8%)

Query: 16  ANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSE 75
           +NS  P   +  +     P   +++LFIQKLRQCCVLFDFVSDPLSDLK+KEVKRA L+E
Sbjct: 60  SNSTPPPTQLSKIKYSGGPQIVKKELFIQKLRQCCVLFDFVSDPLSDLKFKEVKRAGLNE 119

Query: 76  MVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQ 135
           MVEYITH+R+V+TE IYPE V MF+VN+FRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQ
Sbjct: 120 MVEYITHSRDVVTEAIYPEAVTMFSVNLFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQ 179

Query: 136 LVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLG 195
           LVYEFFLRFLESPDFQPNIAKKYIDQKFVL LL+LFDSEDPRERDFLKT LHRIYGKFLG
Sbjct: 180 LVYEFFLRFLESPDFQPNIAKKYIDQKFVLALLDLFDSEDPRERDFLKTILHRIYGKFLG 239

Query: 196 LRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLH 255
           LRAYIR+QIN+IFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHK+FL++VLLPLH
Sbjct: 240 LRAYIRRQINHIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKMFLIRVLLPLH 299

Query: 256 KVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVI 315
           KVKSLSVYHPQLAYCVVQFLEK+S+LTEPV++ LLK+WPKTHSPKEVMFLNELEEILDVI
Sbjct: 300 KVKSLSVYHPQLAYCVVQFLEKESSLTEPVIVGLLKFWPKTHSPKEVMFLNELEEILDVI 359

Query: 316 EPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLY 375
           EPSEF K+MEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAA++LPIMFP+LY
Sbjct: 360 EPSEFSKVMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAARVLPIMFPALY 419

Query: 376 RNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIEN 435
           RNSK+HWNKTIHGLIYNALKLFMEMNQKLFDDCTQQ+KAEK K + +MKEREE W KIE 
Sbjct: 420 RNSKSHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQYKAEKQKGRFRMKEREEMWQKIEE 479

Query: 436 LAKANP---------------------------------------QAQKDPKKDRPLARR 456
           LA+ NP                                       Q  KD KK++ L RR
Sbjct: 480 LARLNPQYPMFRAPPPLPPVYSMETETPTAEDIQLLKRTVETEAVQMLKDIKKEKVLLRR 539

Query: 457 KSELPQDPHTKKALEAHCRADEL--ASQD 483
           KSELPQD +T KALEAH RA+E   ASQ+
Sbjct: 540 KSELPQDVYTIKALEAHKRAEEFLTASQE 568


>gi|31083288 delta isoform of regulatory subunit B56, protein
           phosphatase 2A isoform 3 [Homo sapiens]
          Length = 496

 Score =  775 bits (2001), Expect = 0.0
 Identities = 387/487 (79%), Positives = 422/487 (86%), Gaps = 41/487 (8%)

Query: 38  QEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVH 97
           +++LFIQKLRQCCVLFDFVSDPLSDLK+KEVKRA L+EMVEYITH+R+V+TE IYPE V 
Sbjct: 8   EKELFIQKLRQCCVLFDFVSDPLSDLKFKEVKRAGLNEMVEYITHSRDVVTEAIYPEAVT 67

Query: 98  MFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKK 157
           MF+VN+FRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKK
Sbjct: 68  MFSVNLFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKK 127

Query: 158 YIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEH 217
           YIDQKFVL LL+LFDSEDPRERDFLKT LHRIYGKFLGLRAYIR+QIN+IFYRFIYETEH
Sbjct: 128 YIDQKFVLALLDLFDSEDPRERDFLKTILHRIYGKFLGLRAYIRRQINHIFYRFIYETEH 187

Query: 218 HNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEK 277
           HNGIAELLEILGSIINGFALPLKEEHK+FL++VLLPLHKVKSLSVYHPQLAYCVVQFLEK
Sbjct: 188 HNGIAELLEILGSIINGFALPLKEEHKMFLIRVLLPLHKVKSLSVYHPQLAYCVVQFLEK 247

Query: 278 DSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSS 337
           +S+LTEPV++ LLK+WPKTHSPKEVMFLNELEEILDVIEPSEF K+MEPLFRQLAKCVSS
Sbjct: 248 ESSLTEPVIVGLLKFWPKTHSPKEVMFLNELEEILDVIEPSEFSKVMEPLFRQLAKCVSS 307

Query: 338 PHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLF 397
           PHFQVAERALYYWNNEYIMSLISDNAA++LPIMFP+LYRNSK+HWNKTIHGLIYNALKLF
Sbjct: 308 PHFQVAERALYYWNNEYIMSLISDNAARVLPIMFPALYRNSKSHWNKTIHGLIYNALKLF 367

Query: 398 MEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANP---------------- 441
           MEMNQKLFDDCTQQ+KAEK K + +MKEREE W KIE LA+ NP                
Sbjct: 368 MEMNQKLFDDCTQQYKAEKQKGRFRMKEREEMWQKIEELARLNPQYPMFRAPPPLPPVYS 427

Query: 442 -----------------------QAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADE 478
                                  Q  KD KK++ L RRKSELPQD +T KALEAH RA+E
Sbjct: 428 METETPTAEDIQLLKRTVETEAVQMLKDIKKEKVLLRRKSELPQDVYTIKALEAHKRAEE 487

Query: 479 L--ASQD 483
              ASQ+
Sbjct: 488 FLTASQE 494


>gi|5453956 epsilon isoform of regulatory subunit B56, protein
           phosphatase 2A [Homo sapiens]
          Length = 467

 Score =  615 bits (1586), Expect = e-176
 Identities = 300/416 (72%), Positives = 353/416 (84%), Gaps = 4/416 (0%)

Query: 21  PFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYI 80
           P +   L  ++DVP ++Q +LF++KL+QCCV+FDF+ D LSDLK KE KR+ L+E+V+YI
Sbjct: 42  PIELTPLPLLKDVPSSEQPELFLKKLQQCCVIFDFM-DTLSDLKMKEYKRSTLNELVDYI 100

Query: 81  THNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEF 140
           T +R  +TE  YPEVV M + N+FRTLPPS +    EFDPEEDEPTLEA+WPHLQLVYEF
Sbjct: 101 TISRGCLTEQTYPEVVRMVSCNIFRTLPPSDSN---EFDPEEDEPTLEASWPHLQLVYEF 157

Query: 141 FLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYI 200
           F+RFLES +FQP+IAKKYIDQKFVLQLLELFDSEDPRERD+LKT LHRIYGKFLGLRA+I
Sbjct: 158 FIRFLESQEFQPSIAKKYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFI 217

Query: 201 RKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSL 260
           RKQINNIF RF+YETEH NG+AELLEILGSIINGFALPLK EHK FL+KVL+PLH V+SL
Sbjct: 218 RKQINNIFLRFVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSL 277

Query: 261 SVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEF 320
           S++H QLAYC+VQFLEKD +LTEPV+  L+K+WPKT S KEVMFL ELEEILDVIEPS+F
Sbjct: 278 SLFHAQLAYCIVQFLEKDPSLTEPVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQF 337

Query: 321 VKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKT 380
           VKI EPLF+Q+AKCVSSPHFQVAERALYYWNNEYIMSLI +N+  ILPIMF SLYR SK 
Sbjct: 338 VKIQEPLFKQIAKCVSSPHFQVAERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKE 397

Query: 381 HWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENL 436
           HWN  I  L+YN LK FMEMN  +FD+ T  +K+++ +EK K KEREE W K+E+L
Sbjct: 398 HWNPAIVALVYNVLKAFMEMNSTMFDELTATYKSDRQREKKKEKEREELWKKLEDL 453


>gi|5453950 protein phosphatase 2, regulatory subunit B (B56), alpha
           isoform [Homo sapiens]
          Length = 486

 Score =  609 bits (1570), Expect = e-174
 Identities = 296/410 (72%), Positives = 345/410 (84%), Gaps = 4/410 (0%)

Query: 27  LLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNV 86
           L  ++D    +Q++LF QKL+QCC+LFDF+ D +SDLK KE+KRA L+E+VEY++ NR V
Sbjct: 56  LPQLKDATSNEQQELFCQKLQQCCILFDFM-DSVSDLKSKEIKRATLNELVEYVSTNRGV 114

Query: 87  ITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLE 146
           I E  Y ++V M + N+FRTLPPS NP   +FDPEEDEPTLEA+WPH+QLVYEFFLRFLE
Sbjct: 115 IVESAYSDIVKMISANIFRTLPPSDNP---DFDPEEDEPTLEASWPHIQLVYEFFLRFLE 171

Query: 147 SPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINN 206
           SPDFQP+IAK+YIDQKFV QLLELFDSEDPRERDFLKT LHRIYGKFLGLRA+IRKQINN
Sbjct: 172 SPDFQPSIAKRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINN 231

Query: 207 IFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQ 266
           IF RFIYETEH NG+AELLEILGSIINGFALPLK EHK FL+KVL+P+H  K L+++H Q
Sbjct: 232 IFLRFIYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQ 291

Query: 267 LAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEP 326
           LAYCVVQFLEKD+TLTEPV+  LLK+WPKT S KEVMFL E+EEILDVIEP++F KI EP
Sbjct: 292 LAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEP 351

Query: 327 LFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTI 386
           LF+Q++KCVSS HFQVAERALY+WNNEYI+SLI +N  KILPIMF SLY+ SK HWN TI
Sbjct: 352 LFKQISKCVSSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTI 411

Query: 387 HGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENL 436
             L+YN LK  MEMN KLFDD T  +KAE+ +EK K  EREE W K+E L
Sbjct: 412 VALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEEL 461


>gi|5453952 beta isoform of regulatory subunit B56, protein
           phosphatase 2A [Homo sapiens]
          Length = 497

 Score =  593 bits (1529), Expect = e-169
 Identities = 291/426 (68%), Positives = 349/426 (81%), Gaps = 5/426 (1%)

Query: 30  IRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITE 89
           ++DVP ++  +L  +KL QC V+FDF+ D ++DLK KEVKRAAL+E+VE +   R V+ E
Sbjct: 65  LKDVPASELHELLSRKLAQCGVMFDFL-DCVADLKGKEVKRAALNELVECVGSTRGVLIE 123

Query: 90  PIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPD 149
           P+YP+++ M +VN+FRTLPPS NP   EFDPEEDEP LE +WPHLQLVYEFFLRFLESPD
Sbjct: 124 PVYPDIIRMISVNIFRTLPPSENP---EFDPEEDEPNLEPSWPHLQLVYEFFLRFLESPD 180

Query: 150 FQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFY 209
           FQP++AK+Y+DQKFVL LLELFDSEDPRER++LKT LHR+YGKFLGLRAYIRKQ N+IF 
Sbjct: 181 FQPSVAKRYVDQKFVLMLLELFDSEDPREREYLKTILHRVYGKFLGLRAYIRKQCNHIFL 240

Query: 210 RFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAY 269
           RFIYE EH NG+AELLEILGSIINGFALPLK EHK FL++VL+PLH VKSLSV+H QLAY
Sbjct: 241 RFIYEFEHFNGVAELLEILGSIINGFALPLKTEHKQFLVRVLIPLHSVKSLSVFHAQLAY 300

Query: 270 CVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFR 329
           CVVQFLEKD+TLTE V+  LLKYWPKT + KEVMFL E+EEILDVIEPS+FVKI EPLF+
Sbjct: 301 CVVQFLEKDATLTEHVIRGLLKYWPKTCTQKEVMFLGEMEEILDVIEPSQFVKIQEPLFK 360

Query: 330 QLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGL 389
           Q+A+CVSSPHFQVAERALY+WNNEYI+SLI DN   +LP +F +LY+ SK HWN+TI  L
Sbjct: 361 QVARCVSSPHFQVAERALYFWNNEYILSLIEDNCHTVLPAVFGTLYQVSKEHWNQTIVSL 420

Query: 390 IYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQAQKDPKK 449
           IYN LK FMEMN KLFD+ T  +K EK +E+ K +ER+E W  +E L     Q  +   K
Sbjct: 421 IYNVLKTFMEMNGKLFDELTASYKLEKQQEQQKAQERQELWQGLEELRLRRLQGTQG-AK 479

Query: 450 DRPLAR 455
           + PL R
Sbjct: 480 EAPLQR 485


>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
           sapiens]
          Length = 940

 Score = 33.9 bits (76), Expect = 0.34
 Identities = 40/195 (20%), Positives = 78/195 (40%), Gaps = 31/195 (15%)

Query: 299 PKEVM-----FLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNE 353
           PKE++     FLN   E+  V   S+   +M+   + +++C               + N 
Sbjct: 8   PKELLKGLDSFLNRDGEVKSVDGISKIFSLMKEARKMVSRCT--------------YLNI 53

Query: 354 YIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFK 413
            + +   +   K + +    L  N  T+   T +  +   + L ++      D   Q   
Sbjct: 54  LLQTRSPEILVKFIDVGGYKLLNNWLTYSKTTNNIPLLQQILLTLQHLPLTVDHLKQNNT 113

Query: 414 AEKLKEKLKMKEREEA----------WVKIENLAKANPQAQKDPKKDRPLARRKSELPQD 463
           A+ +K+  K  E EE           W+ +     +   A+KD KK +   + ++ LP+ 
Sbjct: 114 AKLVKQLSKSSEDEELRKLASVLVSDWMAVIRSQSSTQPAEKDKKKRKDEGKSRTTLPER 173

Query: 464 PHTKKALEAHCRADE 478
           P T+  ++A  RA+E
Sbjct: 174 PLTE--VKAETRAEE 186


>gi|4505727 peroxisomal biogenesis factor 3 [Homo sapiens]
          Length = 373

 Score = 33.9 bits (76), Expect = 0.34
 Identities = 33/163 (20%), Positives = 77/163 (47%), Gaps = 18/163 (11%)

Query: 219 NGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKD 278
           +G+ EL+ ++   +      +  +H + LL +   L ++++L   H   ++     + KD
Sbjct: 174 DGLTELITVIKQAVQKVLGSVSLKHSLSLLDLEQKLKEIRNLVEQHKSSSW-----INKD 228

Query: 279 STLTEPVVMALLKYWPKTH--------SPKEVMFLNELEEILDVIEPSEFVKIMEP-LFR 329
            +  +P++   +    +T         SP+++  +  L E  D++E  +F  ++   L R
Sbjct: 229 GS--KPLLCHYMMPDEETPLAVQACGLSPRDITTIKLLNETRDMLESPDFSTVLNTCLNR 286

Query: 330 QLAKCVSS--PHFQVAERALYYWNNEYIMSLISDNAAKILPIM 370
             ++ + +    F+  E+ L + N+   +S +S   AKI+PI+
Sbjct: 287 GFSRLLDNMAEFFRPTEQDLQHGNSMNSLSSVSLPLAKIIPIV 329


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 16/73 (21%), Positives = 39/73 (53%), Gaps = 3/73 (4%)

Query: 409 TQQFKAEKLKEKLKM---KEREEAWVKIENLAKANPQAQKDPKKDRPLARRKSELPQDPH 465
           T++ + E+ K++LK    +ER E W+K+E   +   Q +++ +  R    R+ +  +   
Sbjct: 464 TERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQE 523

Query: 466 TKKALEAHCRADE 478
            ++ L+   R+++
Sbjct: 524 EEERLQQRLRSEQ 536


>gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo
           sapiens]
          Length = 1905

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 3/68 (4%)

Query: 413 KAEKLKEKLKMKEREEAWVK-IENLAKANP--QAQKDPKKDRPLARRKSELPQDPHTKKA 469
           K EKLKEK+K +++E+  +K  E + KA P  +A K     R L  R+ +       KK 
Sbjct: 764 KQEKLKEKVKREKKEKVKMKEKEEVTKAKPACKADKTLATQRRLEERQRQQMILEEMKKP 823

Query: 470 LEAHCRAD 477
            E  C  D
Sbjct: 824 TEDMCLTD 831


>gi|254039614 coiled-coil domain containing 120 isoform 4 [Homo
           sapiens]
          Length = 618

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 26/99 (26%), Positives = 44/99 (44%), Gaps = 16/99 (16%)

Query: 398 MEMNQKLFDDCTQQFKAEKLKEKLKMKE--REEAWVKIENLAKA-----------NPQAQ 444
           ME+   LF +   Q K+E+L+  L  +   +E   +K++ L K             P+  
Sbjct: 1   MEVKAALFGEAAPQVKSERLRGLLDRQRTLQEALSLKLQELRKVCLQEAELTGQLPPECP 60

Query: 445 KDPKKDRPLARRKSELPQ---DPHTKKALEAHCRADELA 480
            +P +   L RR+    +    PH  +A  + C A+ELA
Sbjct: 61  LEPGERPQLVRRRPPTARAYPPPHPNQAHHSLCPAEELA 99


>gi|254039612 coiled-coil domain containing 120 isoform 2 [Homo
           sapiens]
          Length = 649

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 26/99 (26%), Positives = 44/99 (44%), Gaps = 16/99 (16%)

Query: 398 MEMNQKLFDDCTQQFKAEKLKEKLKMKE--REEAWVKIENLAKA-----------NPQAQ 444
           ME+   LF +   Q K+E+L+  L  +   +E   +K++ L K             P+  
Sbjct: 1   MEVKAALFGEAAPQVKSERLRGLLDRQRTLQEALSLKLQELRKVCLQEAELTGQLPPECP 60

Query: 445 KDPKKDRPLARRKSELPQ---DPHTKKALEAHCRADELA 480
            +P +   L RR+    +    PH  +A  + C A+ELA
Sbjct: 61  LEPGERPQLVRRRPPTARAYPPPHPNQAHHSLCPAEELA 99


>gi|5453974 protein kinase N2 [Homo sapiens]
          Length = 984

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 23/75 (30%), Positives = 36/75 (48%), Gaps = 3/75 (4%)

Query: 402 QKL-FDDCTQQFKAEKLKEKLKMKEREEAWVK--IENLAKANPQAQKDPKKDRPLARRKS 458
           QKL F D   Q K + +K+++K + R+E  +K   ENL K     +     D  L +   
Sbjct: 32  QKLDFSDTMVQQKLDDIKDRIKREIRKELKIKEGAENLRKVTTDKKSLAYVDNILKKSNK 91

Query: 459 ELPQDPHTKKALEAH 473
           +L +  H  + L AH
Sbjct: 92  KLEELHHKLQELNAH 106


>gi|222080092 WD repeat domain 91 [Homo sapiens]
          Length = 747

 Score = 31.2 bits (69), Expect = 2.2
 Identities = 36/137 (26%), Positives = 55/137 (40%), Gaps = 31/137 (22%)

Query: 36  ADQEKLF-----IQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEP 90
           AD+EK F     + +L+Q   ++D  +  L D  W  ++R   S +            E 
Sbjct: 34  ADKEKGFRVDKIVDQLQQLMQVYDLAA--LRDY-WSYLERRLFSRL------------ED 78

Query: 91  IYPEVVHMFAVNMFR-----TLPPSSNPTGAEFDPEE-DEPTLEAAWPHLQLVYEFFLRF 144
           IY   +H    ++FR     T+  + N    EF  ++  E   +A W        F L F
Sbjct: 79  IYRPTIHKLKTSLFRFYLVYTIQTNRNDKAQEFFAKQATELQNQAEWKDW-----FVLPF 133

Query: 145 LESPDFQPNIAKKYIDQ 161
           L SPD  P  A  +  Q
Sbjct: 134 LPSPDTNPTFATYFSRQ 150


>gi|110611228 utrophin [Homo sapiens]
          Length = 3433

 Score = 30.4 bits (67), Expect = 3.8
 Identities = 16/53 (30%), Positives = 25/53 (47%), Gaps = 2/53 (3%)

Query: 249  KVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKE 301
            KVL    + K     HP+L Y  VQ + +   L  P+   L+  WP+ + P +
Sbjct: 3131 KVLKNKFRSKKYFAKHPRLGYLPVQTVLEGDNLETPI--TLISMWPEHYDPSQ 3181


>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform
           a [Homo sapiens]
          Length = 1556

 Score = 30.4 bits (67), Expect = 3.8
 Identities = 41/197 (20%), Positives = 81/197 (41%), Gaps = 16/197 (8%)

Query: 271 VVQFLEKDSTLTEPVVMA---LLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPL 327
           + + L++D+  T+  + A   L   WP+ H    +  L+     LD    SE +++   L
Sbjct: 505 LTEALDEDADPTKSALSAVASLAAAWPQLHQGCSLKSLD-----LDSCTLSEILRL-HIL 558

Query: 328 FRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIH 387
                   ++  ++  +R  +   ++  M L   N + +  +   S+Y  +     K +H
Sbjct: 559 ASGADVTSANAKYRYQKRGGFDATDDACMELRLSNPSLVKKLSSTSVYDLTPGEKMKILH 618

Query: 388 GLIYNALKL-----FMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQ 442
            L    L L     F+E    +     Q+F+   LK +   KEREEA  +I    +   +
Sbjct: 619 ALCGKLLTLVSTRDFIEDYVDILRQAKQEFRE--LKAEQHRKEREEAAARIRKRKEEKLK 676

Query: 443 AQKDPKKDRPLARRKSE 459
            Q+   K++    ++ E
Sbjct: 677 EQEQKMKEKQEKLKEDE 693


>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
          Length = 1670

 Score = 30.0 bits (66), Expect = 4.9
 Identities = 24/97 (24%), Positives = 45/97 (46%), Gaps = 4/97 (4%)

Query: 391 YNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKI----ENLAKANPQAQKD 446
           YN  +L +E   K+  D  ++ + ++L+   K K  +EA  K     ENL K N + +++
Sbjct: 627 YNTQQLALEQLYKIKRDKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKENLRKEEE 686

Query: 447 PKKDRPLARRKSELPQDPHTKKALEAHCRADELASQD 483
            K+ R    +  E  Q+   K   +     D L +++
Sbjct: 687 EKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLKAEE 723


>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
          Length = 1697

 Score = 30.0 bits (66), Expect = 4.9
 Identities = 24/97 (24%), Positives = 45/97 (46%), Gaps = 4/97 (4%)

Query: 391 YNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKI----ENLAKANPQAQKD 446
           YN  +L +E   K+  D  ++ + ++L+   K K  +EA  K     ENL K N + +++
Sbjct: 654 YNTQQLALEQLYKIKRDKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKENLRKEEE 713

Query: 447 PKKDRPLARRKSELPQDPHTKKALEAHCRADELASQD 483
            K+ R    +  E  Q+   K   +     D L +++
Sbjct: 714 EKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLKAEE 750


>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
          Length = 1249

 Score = 30.0 bits (66), Expect = 4.9
 Identities = 24/97 (24%), Positives = 45/97 (46%), Gaps = 4/97 (4%)

Query: 391 YNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKI----ENLAKANPQAQKD 446
           YN  +L +E   K+  D  ++ + ++L+   K K  +EA  K     ENL K N + +++
Sbjct: 654 YNTQQLALEQLYKIKRDKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKENLRKEEE 713

Query: 447 PKKDRPLARRKSELPQDPHTKKALEAHCRADELASQD 483
            K+ R    +  E  Q+   K   +     D L +++
Sbjct: 714 EKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLKAEE 750


>gi|163792208 Rho guanine exchange factor 16 [Homo sapiens]
          Length = 709

 Score = 30.0 bits (66), Expect = 4.9
 Identities = 16/60 (26%), Positives = 34/60 (56%), Gaps = 2/60 (3%)

Query: 212 IYETEHHNGIAELLEILGSIINGFALPLKEEHKI-FLLKVLLPLHKVKSLSVYHPQLAYC 270
           + + EHH+  + +L++LG+    F   L++ HK   L++ +  + +  +   +HP +AYC
Sbjct: 320 VTQMEHHHLFSNILDVLGA-SQRFFEDLEQRHKAQVLVEDISDILEEHAEKHFHPYIAYC 378


>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
          Length = 808

 Score = 29.6 bits (65), Expect = 6.4
 Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 3/56 (5%)

Query: 413 KAEKLKEKLKMKEREEAWVKIENLAKANPQAQKDPKK--DRPLA-RRKSELPQDPH 465
           K EK +EK + K+ +E   + +   K   + QK  KK   R L+ RRK++ P  PH
Sbjct: 737 KQEKEREKERQKQEKEREKQEKEREKQEKERQKQEKKAQGRKLSLRRKADGPPGPH 792


>gi|154350213 hypothetical protein LOC79591 [Homo sapiens]
          Length = 689

 Score = 29.6 bits (65), Expect = 6.4
 Identities = 30/118 (25%), Positives = 48/118 (40%), Gaps = 14/118 (11%)

Query: 155 AKKYIDQKFVLQLLELFDSEDP--------RERDFLKTTLHRIYGKFLGLRA----YIRK 202
           +KK + +K VL   E+F +EDP         E   +K  L  + GK   L       I+ 
Sbjct: 17  SKKPLKEKVVLMYDEIFMTEDPSKCSPRFWEELFLMKVNLEYLEGKLESLDGEELMKIKD 76

Query: 203 QINNIFYRFIYE--TEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVK 258
            IN +F   I     EH   +   L+ L ++I G     K      ++ +L+   K +
Sbjct: 77  NINCLFQHCIQALGEEHPIRVVNALQTLCALIRGVHQKNKSTSGFDIINMLMGFDKAE 134


>gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]
          Length = 4471

 Score = 29.3 bits (64), Expect = 8.4
 Identities = 24/96 (25%), Positives = 45/96 (46%), Gaps = 11/96 (11%)

Query: 349 YWNNEYIMSLISDNAAKILP--IMFPSLYRN-----SKTHWNKTIHGLIYNALKLFMEMN 401
           Y  +E+ + ++ D   KI    +  P LY+N        +W +++   I + +  F E+ 
Sbjct: 534 YVMDEFKIEVLIDIINKIFVQNLENPPLYKNHPPVAGAIYWERSLFFRIKHTILRFQEVQ 593

Query: 402 QKLFDDCTQQFKAEKLKEKLKMKERE----EAWVKI 433
           + L  D  Q+ K + L+    MKE E    E W+++
Sbjct: 594 EILDSDRGQEVKQKYLEVGRTMKEYEDRKYEQWMEV 629


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 29.3 bits (64), Expect = 8.4
 Identities = 19/67 (28%), Positives = 36/67 (53%), Gaps = 3/67 (4%)

Query: 395 KLFMEMNQKLFDDCTQQFKA-EKLKEKL-KMKEREEAWVKIENLAKANPQAQKDPKKDRP 452
           K   E  QK+ D   + ++  E+L+EK  +M+E+E+ W ++E + +   + Q+  KK R 
Sbjct: 383 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKM-REEKKMQEQEKKTRD 441

Query: 453 LARRKSE 459
              +  E
Sbjct: 442 QEEKMQE 448


>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
           sapiens]
          Length = 929

 Score = 29.3 bits (64), Expect = 8.4
 Identities = 20/70 (28%), Positives = 37/70 (52%), Gaps = 8/70 (11%)

Query: 402 QKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQAQKDPKKDRPLARRKSELP 461
           +KLF++       EK+KEK K K+++E   K E   +   + ++  K++R   +R+ E  
Sbjct: 687 EKLFEE------KEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKRER--EKREKEKE 738

Query: 462 QDPHTKKALE 471
           +  H K  +E
Sbjct: 739 KHKHEKIKVE 748


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,385,219
Number of Sequences: 37866
Number of extensions: 819487
Number of successful extensions: 3191
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 3136
Number of HSP's gapped (non-prelim): 69
length of query: 485
length of database: 18,247,518
effective HSP length: 106
effective length of query: 379
effective length of database: 14,233,722
effective search space: 5394580638
effective search space used: 5394580638
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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