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Search of human proteins with 31077081
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31077081 frataxin isoform 1 preproprotein [Homo sapiens]
(210 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31077081 frataxin isoform 1 preproprotein [Homo sapiens] 427 e-120
gi|31742516 frataxin isoform 2 preproprotein [Homo sapiens] 325 1e-89
gi|239787198 frataxin isoform 3 preproprotein [Homo sapiens] 325 1e-89
gi|169164783 PREDICTED: hypothetical protein [Homo sapiens] 31 0.87
gi|169163482 PREDICTED: hypothetical protein [Homo sapiens] 31 0.87
gi|9506363 SAM and SH3 domain containing 3 [Homo sapiens] 30 1.5
gi|47458820 signal transducer and activator of transcription 3 i... 30 1.5
gi|21618338 signal transducer and activator of transcription 3 i... 30 1.5
gi|21618340 signal transducer and activator of transcription 3 i... 30 1.5
gi|239751624 PREDICTED: hypothetical protein XP_002347938 [Homo ... 29 2.5
gi|239746135 PREDICTED: hypothetical protein XP_002344205 [Homo ... 29 2.5
gi|34486092 adenylate cyclase 5 [Homo sapiens] 29 2.5
gi|103472011 ubiquitin-conjugating enzyme E2-like isoform a [Hom... 29 2.5
gi|103472015 ubiquitin-conjugating enzyme E2-like isoform b [Hom... 29 2.5
gi|89941479 hypothetical protein LOC148137 [Homo sapiens] 29 2.5
gi|222446609 rai-like protein [Homo sapiens] 28 4.3
gi|239757070 PREDICTED: hypothetical protein [Homo sapiens] 28 4.3
gi|239751580 PREDICTED: hypothetical protein [Homo sapiens] 28 4.3
gi|239746092 PREDICTED: hypothetical protein XP_002343656 [Homo ... 28 4.3
gi|169168202 PREDICTED: hypothetical protein [Homo sapiens] 28 5.6
gi|169167967 PREDICTED: hypothetical protein [Homo sapiens] 28 5.6
gi|169167681 PREDICTED: hypothetical protein [Homo sapiens] 28 5.6
gi|4557485 ceruloplasmin precursor [Homo sapiens] 28 7.4
gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens] 27 9.6
>gi|31077081 frataxin isoform 1 preproprotein [Homo sapiens]
Length = 210
Score = 427 bits (1098), Expect = e-120
Identities = 210/210 (100%), Positives = 210/210 (100%)
Query: 1 MWTLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQR 60
MWTLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQR
Sbjct: 1 MWTLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQR 60
Query: 61 GLNQIWNVKKQSVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTF 120
GLNQIWNVKKQSVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTF
Sbjct: 61 GLNQIWNVKKQSVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTF 120
Query: 121 EDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGV 180
EDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGV
Sbjct: 121 EDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGV 180
Query: 181 SLHELLAAELTKALKTKLDLSSLAYSGKDA 210
SLHELLAAELTKALKTKLDLSSLAYSGKDA
Sbjct: 181 SLHELLAAELTKALKTKLDLSSLAYSGKDA 210
>gi|31742516 frataxin isoform 2 preproprotein [Homo sapiens]
Length = 196
Score = 325 bits (834), Expect = 1e-89
Identities = 160/160 (100%), Positives = 160/160 (100%)
Query: 1 MWTLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQR 60
MWTLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQR
Sbjct: 1 MWTLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQR 60
Query: 61 GLNQIWNVKKQSVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTF 120
GLNQIWNVKKQSVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTF
Sbjct: 61 GLNQIWNVKKQSVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTF 120
Query: 121 EDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPS 160
EDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPS
Sbjct: 121 EDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPS 160
>gi|239787198 frataxin isoform 3 preproprotein [Homo sapiens]
Length = 171
Score = 325 bits (834), Expect = 1e-89
Identities = 160/160 (100%), Positives = 160/160 (100%)
Query: 1 MWTLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQR 60
MWTLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQR
Sbjct: 1 MWTLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQR 60
Query: 61 GLNQIWNVKKQSVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTF 120
GLNQIWNVKKQSVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTF
Sbjct: 61 GLNQIWNVKKQSVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTF 120
Query: 121 EDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPS 160
EDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPS
Sbjct: 121 EDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPS 160
>gi|169164783 PREDICTED: hypothetical protein [Homo sapiens]
Length = 396
Score = 30.8 bits (68), Expect = 0.87
Identities = 30/88 (34%), Positives = 39/88 (44%), Gaps = 12/88 (13%)
Query: 5 GRRAVAGLLASPSPAQAQTLTRVPRPAELAPL--CGRRGLRTDIDATCTPRRASSNQRGL 62
G+R GL S PA A++ R PRP L P G LR T R SS+ G+
Sbjct: 19 GQRRAPGLPRSSGPAWAESRARPPRPRGLEPRHPPGSPALRP------TDRTCSSSSAGV 72
Query: 63 -NQIWNVKKQSVYL---MNLRKSGTLGH 86
+ + SV L + L + TLGH
Sbjct: 73 GGGVGGAQPGSVPLGQHLALERGRTLGH 100
>gi|169163482 PREDICTED: hypothetical protein [Homo sapiens]
Length = 396
Score = 30.8 bits (68), Expect = 0.87
Identities = 30/88 (34%), Positives = 39/88 (44%), Gaps = 12/88 (13%)
Query: 5 GRRAVAGLLASPSPAQAQTLTRVPRPAELAPL--CGRRGLRTDIDATCTPRRASSNQRGL 62
G+R GL S PA A++ R PRP L P G LR T R SS+ G+
Sbjct: 19 GQRRAPGLPRSSGPAWAESRARPPRPRGLEPRHPPGSPALRP------TDRTCSSSSAGV 72
Query: 63 -NQIWNVKKQSVYL---MNLRKSGTLGH 86
+ + SV L + L + TLGH
Sbjct: 73 GGGVGGAQPGSVPLGQHLALERGRTLGH 100
>gi|9506363 SAM and SH3 domain containing 3 [Homo sapiens]
Length = 380
Score = 30.0 bits (66), Expect = 1.5
Identities = 17/43 (39%), Positives = 19/43 (44%), Gaps = 1/43 (2%)
Query: 4 LGRRAVAGL-LASPSPAQAQTLTRVPRPAELAPLCGRRGLRTD 45
L R+A G L SPSP P P P CGR + TD
Sbjct: 141 LSRQASTGSELCSPSPGSGSFGEEPPAPQYTGPFCGRARVHTD 183
>gi|47458820 signal transducer and activator of transcription 3
isoform 3 [Homo sapiens]
Length = 722
Score = 30.0 bits (66), Expect = 1.5
Identities = 18/75 (24%), Positives = 33/75 (44%)
Query: 79 RKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGG 138
++ G HP + T +++ E+ L + + +DL K E+ F T+K G
Sbjct: 124 QQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQG 183
Query: 139 DLGTYVINKQTPNKQ 153
D+ N Q+ +Q
Sbjct: 184 DMQDLNGNNQSVTRQ 198
>gi|21618338 signal transducer and activator of transcription 3
isoform 2 [Homo sapiens]
Length = 769
Score = 30.0 bits (66), Expect = 1.5
Identities = 18/75 (24%), Positives = 33/75 (44%)
Query: 79 RKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGG 138
++ G HP + T +++ E+ L + + +DL K E+ F T+K G
Sbjct: 124 QQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQG 183
Query: 139 DLGTYVINKQTPNKQ 153
D+ N Q+ +Q
Sbjct: 184 DMQDLNGNNQSVTRQ 198
>gi|21618340 signal transducer and activator of transcription 3
isoform 1 [Homo sapiens]
Length = 770
Score = 30.0 bits (66), Expect = 1.5
Identities = 18/75 (24%), Positives = 33/75 (44%)
Query: 79 RKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGG 138
++ G HP + T +++ E+ L + + +DL K E+ F T+K G
Sbjct: 124 QQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQG 183
Query: 139 DLGTYVINKQTPNKQ 153
D+ N Q+ +Q
Sbjct: 184 DMQDLNGNNQSVTRQ 198
>gi|239751624 PREDICTED: hypothetical protein XP_002347938 [Homo
sapiens]
Length = 244
Score = 29.3 bits (64), Expect = 2.5
Identities = 14/27 (51%), Positives = 17/27 (62%)
Query: 4 LGRRAVAGLLASPSPAQAQTLTRVPRP 30
+GRRA AGL A P P QA L + +P
Sbjct: 85 VGRRAAAGLRAHPLPPQAPPLAQSSQP 111
>gi|239746135 PREDICTED: hypothetical protein XP_002344205 [Homo
sapiens]
Length = 244
Score = 29.3 bits (64), Expect = 2.5
Identities = 14/27 (51%), Positives = 17/27 (62%)
Query: 4 LGRRAVAGLLASPSPAQAQTLTRVPRP 30
+GRRA AGL A P P QA L + +P
Sbjct: 85 VGRRAAAGLRAHPLPPQAPPLAQSSQP 111
>gi|34486092 adenylate cyclase 5 [Homo sapiens]
Length = 1261
Score = 29.3 bits (64), Expect = 2.5
Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 16/102 (15%)
Query: 78 LRKSGTLGHP----GSLDETTYERLAEETLDSLAEFFEDLADK-----PYTFEDYDVSFG 128
L K T+G L+++TY+++ + + +LA+F L D+ ++F ++ + G
Sbjct: 1119 LEKIKTIGSTYMAASGLNDSTYDKVGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIG 1178
Query: 129 SGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTG 170
+ V G VI + P IW + + R D TG
Sbjct: 1179 LNIGPVVAG------VIGARKPQYDIW-GNTVNVASRMDSTG 1213
>gi|103472011 ubiquitin-conjugating enzyme E2-like isoform a [Homo
sapiens]
Length = 471
Score = 29.3 bits (64), Expect = 2.5
Identities = 12/36 (33%), Positives = 18/36 (50%)
Query: 142 TYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSH 177
T V+ QT K++W+ K W+G+ V SH
Sbjct: 331 TNVLKAQTSGKEVWVIGEQGEDKVLTWSGQEEVVSH 366
>gi|103472015 ubiquitin-conjugating enzyme E2-like isoform b [Homo
sapiens]
Length = 379
Score = 29.3 bits (64), Expect = 2.5
Identities = 12/36 (33%), Positives = 18/36 (50%)
Query: 142 TYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSH 177
T V+ QT K++W+ K W+G+ V SH
Sbjct: 331 TNVLKAQTSGKEVWVIGEQGEDKVLTWSGQEEVVSH 366
>gi|89941479 hypothetical protein LOC148137 [Homo sapiens]
Length = 425
Score = 29.3 bits (64), Expect = 2.5
Identities = 16/24 (66%), Positives = 17/24 (70%), Gaps = 1/24 (4%)
Query: 14 ASPSPAQAQTLTRVPRPA-ELAPL 36
ASP+PAQAQT T P PA APL
Sbjct: 257 ASPAPAQAQTPTPAPAPASSQAPL 280
>gi|222446609 rai-like protein [Homo sapiens]
Length = 630
Score = 28.5 bits (62), Expect = 4.3
Identities = 12/27 (44%), Positives = 14/27 (51%)
Query: 82 GTLGHPGSLDETTYERLAEETLDSLAE 108
G GHPG L Y R E++ SL E
Sbjct: 17 GLFGHPGMLHRAKYSRFRNESITSLDE 43
>gi|239757070 PREDICTED: hypothetical protein [Homo sapiens]
Length = 195
Score = 28.5 bits (62), Expect = 4.3
Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 7/57 (12%)
Query: 9 VAGLLASPSPAQAQTLTRVPRPAELAP----LCGRRGLRTDIDATCTPRRASSNQRG 61
VAG L P P R P+P P LC GLRT DA+ R A + G
Sbjct: 137 VAGCLPLPRPRDG---ARSPQPLPWKPGLPSLCVASGLRTAPDASAPGRAAKTRSSG 190
>gi|239751580 PREDICTED: hypothetical protein [Homo sapiens]
Length = 195
Score = 28.5 bits (62), Expect = 4.3
Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 7/57 (12%)
Query: 9 VAGLLASPSPAQAQTLTRVPRPAELAP----LCGRRGLRTDIDATCTPRRASSNQRG 61
VAG L P P R P+P P LC GLRT DA+ R A + G
Sbjct: 137 VAGCLPLPRPRDG---ARSPQPLPWKPGLPSLCVASGLRTAPDASAPGRAAKTRSSG 190
>gi|239746092 PREDICTED: hypothetical protein XP_002343656 [Homo
sapiens]
Length = 195
Score = 28.5 bits (62), Expect = 4.3
Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 7/57 (12%)
Query: 9 VAGLLASPSPAQAQTLTRVPRPAELAP----LCGRRGLRTDIDATCTPRRASSNQRG 61
VAG L P P R P+P P LC GLRT DA+ R A + G
Sbjct: 137 VAGCLPLPRPRDG---ARSPQPLPWKPGLPSLCVASGLRTAPDASAPGRAAKTRSSG 190
>gi|169168202 PREDICTED: hypothetical protein [Homo sapiens]
Length = 460
Score = 28.1 bits (61), Expect = 5.6
Identities = 22/67 (32%), Positives = 28/67 (41%), Gaps = 11/67 (16%)
Query: 3 TLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQRGL 62
TL R+ LL SP P R P P GLR D D P R +QR +
Sbjct: 340 TLAFRSRLPLLRSPGPEGTSDAARAPAP----------GLR-DRDLRAAPPRPRPSQRPV 388
Query: 63 NQIWNVK 69
+ ++ VK
Sbjct: 389 SGLFKVK 395
>gi|169167967 PREDICTED: hypothetical protein [Homo sapiens]
Length = 460
Score = 28.1 bits (61), Expect = 5.6
Identities = 22/67 (32%), Positives = 28/67 (41%), Gaps = 11/67 (16%)
Query: 3 TLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQRGL 62
TL R+ LL SP P R P P GLR D D P R +QR +
Sbjct: 340 TLAFRSRLPLLRSPGPEGTSDAARAPAP----------GLR-DRDLRAAPPRPRPSQRPV 388
Query: 63 NQIWNVK 69
+ ++ VK
Sbjct: 389 SGLFKVK 395
>gi|169167681 PREDICTED: hypothetical protein [Homo sapiens]
Length = 460
Score = 28.1 bits (61), Expect = 5.6
Identities = 22/67 (32%), Positives = 28/67 (41%), Gaps = 11/67 (16%)
Query: 3 TLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQRGL 62
TL R+ LL SP P R P P GLR D D P R +QR +
Sbjct: 340 TLAFRSRLPLLRSPGPEGTSDAARAPAP----------GLR-DRDLRAAPPRPRPSQRPV 388
Query: 63 NQIWNVK 69
+ ++ VK
Sbjct: 389 SGLFKVK 395
>gi|4557485 ceruloplasmin precursor [Homo sapiens]
Length = 1065
Score = 27.7 bits (60), Expect = 7.4
Identities = 19/77 (24%), Positives = 36/77 (46%), Gaps = 15/77 (19%)
Query: 59 QRGLNQIWNVKKQSVYLM--------NLRKSGTLGHPGSLDETTYERLAEETLDSLAEFF 110
Q G ++I + K+++YL + K LG G + + ET D +
Sbjct: 57 QNGPDRIGRLYKKALYLQYTDETFRTTIEKPVWLGFLGPI-------IKAETGDKVYVHL 109
Query: 111 EDLADKPYTFEDYDVSF 127
++LA +PYTF + +++
Sbjct: 110 KNLASRPYTFHSHGITY 126
Score = 27.7 bits (60), Expect = 7.4
Identities = 13/41 (31%), Positives = 22/41 (53%)
Query: 104 DSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYV 144
D + F+++A +PY+ + V S +T L G+ TYV
Sbjct: 818 DKVKIIFKNMATRPYSIHAHGVQTESSTVTPTLPGETLTYV 858
>gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens]
Length = 1544
Score = 27.3 bits (59), Expect = 9.6
Identities = 32/113 (28%), Positives = 47/113 (41%), Gaps = 6/113 (5%)
Query: 12 LLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQRGL-NQIW-NVK 69
LLA PSPAQ + RP+ C RG R I++ + + GL ++ W VK
Sbjct: 1370 LLAKPSPAQQTDRSSPVRPSSEKNDC-CRGKRDGINSLERKLKRRLEREGLSSERWERVK 1428
Query: 70 KQSVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTFED 122
K +K L HP ++ ER L AE +D Y+ ++
Sbjct: 1429 KMRT---PKKKKIKLSHPKDMNNFKLERERSYELVRSAETHSLPSDTSYSEQE 1478
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,355,233
Number of Sequences: 37866
Number of extensions: 371890
Number of successful extensions: 754
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 736
Number of HSP's gapped (non-prelim): 26
length of query: 210
length of database: 18,247,518
effective HSP length: 98
effective length of query: 112
effective length of database: 14,536,650
effective search space: 1628104800
effective search space used: 1628104800
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.