Guide to the Human Genome
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Search of human proteins with 29826321

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|29826321 adducin 1 (alpha) isoform b [Homo sapiens]
         (768 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|29826321 adducin 1 (alpha) isoform b [Homo sapiens]               1550   0.0  
gi|29826319 adducin 1 (alpha) isoform a [Homo sapiens]               1467   0.0  
gi|29826325 adducin 1 (alpha) isoform d [Homo sapiens]               1314   0.0  
gi|29826323 adducin 1 (alpha) isoform c [Homo sapiens]               1231   0.0  
gi|9943848 adducin 3 (gamma) isoform a [Homo sapiens]                 679   0.0  
gi|9951927 adducin 3 (gamma) isoform b [Homo sapiens]                 656   0.0  
gi|62912453 adducin 3 (gamma) isoform b [Homo sapiens]                656   0.0  
gi|9257192 adducin 2 isoform a [Homo sapiens]                         617   e-177
gi|9257190 adducin 2 isoform e [Homo sapiens]                         573   e-163
gi|89276787 adducin 2 isoform b [Homo sapiens]                        540   e-153
gi|89276790 adducin 2 isoform d [Homo sapiens]                        208   1e-53
gi|9257180 adducin 2 isoform c [Homo sapiens]                         208   1e-53
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     59   2e-08
gi|30795231 brain abundant, membrane attached signal protein 1 [...    54   4e-07
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             51   4e-06
gi|110349717 titin isoform novex-2 [Homo sapiens]                      51   5e-06
gi|110349713 titin isoform novex-1 [Homo sapiens]                      51   5e-06
gi|110349715 titin isoform N2-B [Homo sapiens]                         51   5e-06
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    50   8e-06
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    50   8e-06
gi|62000702 diacylglycerol kinase kappa [Homo sapiens]                 50   8e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        50   8e-06
gi|22325356 PALM2-AKAP2 protein isoform 2 [Homo sapiens]               50   1e-05
gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens]                50   1e-05
gi|211971074 A kinase (PRKA) anchor protein 2 isoform 2 [Homo sa...    50   1e-05
gi|51873058 A kinase (PRKA) anchor protein 2 isoform 1 [Homo sap...    50   1e-05
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    48   3e-05
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              47   5e-05
gi|110349719 titin isoform N2-A [Homo sapiens]                         47   7e-05
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   47   7e-05

>gi|29826321 adducin 1 (alpha) isoform b [Homo sapiens]
          Length = 768

 Score = 1550 bits (4012), Expect = 0.0
 Identities = 768/768 (100%), Positives = 768/768 (100%)

Query: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60
           MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
Sbjct: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60

Query: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120
           ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
Sbjct: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120

Query: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180
           LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
Sbjct: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180

Query: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240
           LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
Sbjct: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240

Query: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300
           HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
Sbjct: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300

Query: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360
           NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
Sbjct: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360

Query: 361 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS 420
           GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
Sbjct: 361 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS 420

Query: 421 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH 480
           FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH
Sbjct: 421 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH 480

Query: 481 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ 540
           VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
Sbjct: 481 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ 540

Query: 541 NLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTD 600
           NLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTD
Sbjct: 541 NLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTD 600

Query: 601 RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTG 660
           RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTG
Sbjct: 601 RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTG 660

Query: 661 DDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA 720
           DDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA
Sbjct: 661 DDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA 720

Query: 721 EEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKKSDS 768
           EEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKKSDS
Sbjct: 721 EEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKKSDS 768


>gi|29826319 adducin 1 (alpha) isoform a [Homo sapiens]
          Length = 737

 Score = 1467 bits (3797), Expect = 0.0
 Identities = 737/768 (95%), Positives = 737/768 (95%), Gaps = 31/768 (4%)

Query: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60
           MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
Sbjct: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60

Query: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120
           ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
Sbjct: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120

Query: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180
           LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
Sbjct: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180

Query: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240
           LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
Sbjct: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240

Query: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300
           HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
Sbjct: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300

Query: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360
           NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
Sbjct: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360

Query: 361 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS 420
           GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
Sbjct: 361 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS 420

Query: 421 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH 480
           FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTK         
Sbjct: 421 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTK--------- 471

Query: 481 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ 540
                                 WTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
Sbjct: 472 ----------------------WTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ 509

Query: 541 NLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTD 600
           NLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTD
Sbjct: 510 NLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTD 569

Query: 601 RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTG 660
           RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTG
Sbjct: 570 RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTG 629

Query: 661 DDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA 720
           DDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA
Sbjct: 630 DDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA 689

Query: 721 EEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKKSDS 768
           EEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKKSDS
Sbjct: 690 EEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKKSDS 737


>gi|29826325 adducin 1 (alpha) isoform d [Homo sapiens]
          Length = 662

 Score = 1314 bits (3400), Expect = 0.0
 Identities = 651/651 (100%), Positives = 651/651 (100%)

Query: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60
           MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
Sbjct: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60

Query: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120
           ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
Sbjct: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120

Query: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180
           LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
Sbjct: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180

Query: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240
           LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
Sbjct: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240

Query: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300
           HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
Sbjct: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300

Query: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360
           NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
Sbjct: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360

Query: 361 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS 420
           GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
Sbjct: 361 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS 420

Query: 421 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH 480
           FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH
Sbjct: 421 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH 480

Query: 481 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ 540
           VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
Sbjct: 481 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ 540

Query: 541 NLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTD 600
           NLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTD
Sbjct: 541 NLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTD 600

Query: 601 RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEE 651
           RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEE
Sbjct: 601 RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEE 651


>gi|29826323 adducin 1 (alpha) isoform c [Homo sapiens]
          Length = 631

 Score = 1231 bits (3185), Expect = 0.0
 Identities = 620/651 (95%), Positives = 620/651 (95%), Gaps = 31/651 (4%)

Query: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60
           MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
Sbjct: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60

Query: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120
           ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
Sbjct: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120

Query: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180
           LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
Sbjct: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180

Query: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240
           LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
Sbjct: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240

Query: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300
           HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
Sbjct: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300

Query: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360
           NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
Sbjct: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360

Query: 361 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS 420
           GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
Sbjct: 361 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS 420

Query: 421 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH 480
           FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTK         
Sbjct: 421 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTK--------- 471

Query: 481 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ 540
                                 WTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
Sbjct: 472 ----------------------WTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ 509

Query: 541 NLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTD 600
           NLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTD
Sbjct: 510 NLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTD 569

Query: 601 RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEE 651
           RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEE
Sbjct: 570 RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEE 620


>gi|9943848 adducin 3 (gamma) isoform a [Homo sapiens]
          Length = 706

 Score =  679 bits (1751), Expect = 0.0
 Identities = 384/774 (49%), Positives = 503/774 (64%), Gaps = 82/774 (10%)

Query: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60
           M+ D+   V+T+PPP + PHKERYFDR++EN+PEY+RERNM+PDLRQDFNMMEQ+KRV+ 
Sbjct: 1   MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60

Query: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120
           ILQSPAF E+LE +IQEQ KKG NPTGLLALQQIAD++  N  + + + P        +S
Sbjct: 61  ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPP--------LS 112

Query: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180
           LGMVTP+NDL G+D+ +Y KGEKL RCKLA+ YRL DLFGW+ L   +I+ R++ EQ+H 
Sbjct: 113 LGMVTPINDLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHI 172

Query: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240
           +I+P GL +SE TAS+LVK+N+ G++VD+GSTNL ++  GF+ H+AIY+ RPDVKCV+HI
Sbjct: 173 IIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHI 232

Query: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300
           HT A AAVS+MKCG+LPIS E+L LG+VAY+DY G L ++EE++ +QK LGP  KVL+LR
Sbjct: 233 HTLATAAVSSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLR 292

Query: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360
           NHG+V++GE++EEAF+YI N+ +ACEIQV+ LA AGG DNL +L+ +KYKA + +  +  
Sbjct: 293 NHGVVALGETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASG 352

Query: 361 GEGT--GSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTG 418
           G G   GS  KW++GE EFE LMR LDNLGYRTGY YR+P +REK +  SDVE+PA+VT 
Sbjct: 353 GGGVNMGSHQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTA 412

Query: 419 YSFASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGD---EASEEGQNGSSPKSKTKVWTN 475
           +SF  + D+   SPL++  Q+QQREKTRWLNS          EE +NG +   +TK+   
Sbjct: 413 FSF--EDDTVPLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGET-SPRTKITWM 469

Query: 476 ITHDHVKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRN 535
              D  K     +S G  +           ED         PN FVPLNTNP EV E RN
Sbjct: 470 KAEDSSK-----VSGGTPIKI---------ED---------PNQFVPLNTNPNEVLEKRN 506

Query: 536 KIREQNLQDIKTAGPQSQVLCGVVMDR--SLVQGELVTASKAIIEKEYQPHVIVSTTGPN 593
           KIREQN  D+KTAGPQSQ+L G+V+D+  S +Q E         + ++ P        PN
Sbjct: 507 KIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQFE---------DDDHGP-----PAPPN 552

Query: 594 PFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDL 653
           PF+ LT+ ELEEY+R +ERKQ+G E+   E       S     +    P + P KLEE+ 
Sbjct: 553 PFSHLTEGELEEYKRTIERKQQGLEDAEQELLSDDASSVSQIQSQTQSPQNVPEKLEEN- 611

Query: 654 VPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPS--PTEAPTEASPE 711
                    S  +   P +     D+        M + E+E  +  S   T    E    
Sbjct: 612 ---HELFSKSFISMEVPVMVVNGKDD--------MHDVEDELAKRVSRLSTSTTIENIEI 660

Query: 712 PAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKK 765
               P  + E  +P             +GSP KSPSKKKKKFRTPSFLKK+KKK
Sbjct: 661 TIKSPEKIEEVLSP-------------EGSPSKSPSKKKKKFRTPSFLKKNKKK 701


>gi|9951927 adducin 3 (gamma) isoform b [Homo sapiens]
          Length = 674

 Score =  656 bits (1693), Expect = 0.0
 Identities = 377/772 (48%), Positives = 494/772 (63%), Gaps = 110/772 (14%)

Query: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60
           M+ D+   V+T+PPP + PHKERYFDR++EN+PEY+RERNM+PDLRQDFNMMEQ+KRV+ 
Sbjct: 1   MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60

Query: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120
           ILQSPAF E+LE +IQEQ KKG NPTGLLALQQIAD++  N  + + + P        +S
Sbjct: 61  ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPP--------LS 112

Query: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180
           LGMVTP+NDL G+D+ +Y KGEKL RCKLA+ YRL DLFGW+ L   +I+ R++ EQ+H 
Sbjct: 113 LGMVTPINDLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHI 172

Query: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240
           +I+P GL +SE TAS+LVK+N+ G++VD+GSTNL ++  GF+ H+AIY+ RPDVKCV+HI
Sbjct: 173 IIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHI 232

Query: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300
           HT A AAVS+MKCG+LPIS E+L LG+VAY+DY G L ++EE++ +QK LGP  KVL+LR
Sbjct: 233 HTLATAAVSSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLR 292

Query: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360
           NHG+V++GE++EEAF+YI N+ +ACEIQV+ LA AGG DNL +L+ +KYKA + +  +  
Sbjct: 293 NHGVVALGETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASG 352

Query: 361 GEGT--GSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTG 418
           G G   GS  KW++GE EFE LMR LDNLGYRTGY YR+P +REK +  SDVE+PA+VT 
Sbjct: 353 GGGVNMGSHQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTA 412

Query: 419 YSFASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGD---EASEEGQNGSSPKSKTKVWTN 475
           +SF  + D+   SPL++  Q+QQREKTRWLNS          EE +NG +   +TK+   
Sbjct: 413 FSF--EDDTVPLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGET-SPRTKITWM 469

Query: 476 ITHDHVKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRN 535
              D  K     +S G  +           ED         PN FVPLNTNP EV E RN
Sbjct: 470 KAEDSSK-----VSGGTPIKI---------ED---------PNQFVPLNTNPNEVLEKRN 506

Query: 536 KIREQNLQDIKTAGPQSQVLCGVVMDR--SLVQGELVTASKAIIEKEYQPHVIVSTTGPN 593
           KIREQN  D+KTAGPQSQ+L G+V+D+  S +Q E         + ++ P        PN
Sbjct: 507 KIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQFE---------DDDHGP-----PAPPN 552

Query: 594 PFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDL 653
           PF+ LT+ ELEEY+R +ERKQ+G EEN     E   KS      +    P   +  ++D+
Sbjct: 553 PFSHLTEGELEEYKRTIERKQQGLEEN----HELFSKS-----FISMEVPVMVVNGKDDM 603

Query: 654 VPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPA 713
                  D  D    + +    S    +  +     EK EE              SPE +
Sbjct: 604 ------HDVEDELAKRVSRLSTSTTIENIEITIKSPEKIEEV------------LSPEGS 645

Query: 714 PDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKK 765
           P  +P                            SKKKKKFRTPSFLKK+KKK
Sbjct: 646 PSKSP----------------------------SKKKKKFRTPSFLKKNKKK 669


>gi|62912453 adducin 3 (gamma) isoform b [Homo sapiens]
          Length = 674

 Score =  656 bits (1693), Expect = 0.0
 Identities = 377/772 (48%), Positives = 494/772 (63%), Gaps = 110/772 (14%)

Query: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60
           M+ D+   V+T+PPP + PHKERYFDR++EN+PEY+RERNM+PDLRQDFNMMEQ+KRV+ 
Sbjct: 1   MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60

Query: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120
           ILQSPAF E+LE +IQEQ KKG NPTGLLALQQIAD++  N  + + + P        +S
Sbjct: 61  ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPP--------LS 112

Query: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180
           LGMVTP+NDL G+D+ +Y KGEKL RCKLA+ YRL DLFGW+ L   +I+ R++ EQ+H 
Sbjct: 113 LGMVTPINDLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHI 172

Query: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240
           +I+P GL +SE TAS+LVK+N+ G++VD+GSTNL ++  GF+ H+AIY+ RPDVKCV+HI
Sbjct: 173 IIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHI 232

Query: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300
           HT A AAVS+MKCG+LPIS E+L LG+VAY+DY G L ++EE++ +QK LGP  KVL+LR
Sbjct: 233 HTLATAAVSSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLR 292

Query: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360
           NHG+V++GE++EEAF+YI N+ +ACEIQV+ LA AGG DNL +L+ +KYKA + +  +  
Sbjct: 293 NHGVVALGETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASG 352

Query: 361 GEGT--GSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTG 418
           G G   GS  KW++GE EFE LMR LDNLGYRTGY YR+P +REK +  SDVE+PA+VT 
Sbjct: 353 GGGVNMGSHQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTA 412

Query: 419 YSFASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGD---EASEEGQNGSSPKSKTKVWTN 475
           +SF  + D+   SPL++  Q+QQREKTRWLNS          EE +NG +   +TK+   
Sbjct: 413 FSF--EDDTVPLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGET-SPRTKITWM 469

Query: 476 ITHDHVKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRN 535
              D  K     +S G  +           ED         PN FVPLNTNP EV E RN
Sbjct: 470 KAEDSSK-----VSGGTPIKI---------ED---------PNQFVPLNTNPNEVLEKRN 506

Query: 536 KIREQNLQDIKTAGPQSQVLCGVVMDR--SLVQGELVTASKAIIEKEYQPHVIVSTTGPN 593
           KIREQN  D+KTAGPQSQ+L G+V+D+  S +Q E         + ++ P        PN
Sbjct: 507 KIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQFE---------DDDHGP-----PAPPN 552

Query: 594 PFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDL 653
           PF+ LT+ ELEEY+R +ERKQ+G EEN     E   KS      +    P   +  ++D+
Sbjct: 553 PFSHLTEGELEEYKRTIERKQQGLEEN----HELFSKS-----FISMEVPVMVVNGKDDM 603

Query: 654 VPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPA 713
                  D  D    + +    S    +  +     EK EE              SPE +
Sbjct: 604 ------HDVEDELAKRVSRLSTSTTIENIEITIKSPEKIEEV------------LSPEGS 645

Query: 714 PDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKK 765
           P  +P                            SKKKKKFRTPSFLKK+KKK
Sbjct: 646 PSKSP----------------------------SKKKKKFRTPSFLKKNKKK 669


>gi|9257192 adducin 2 isoform a [Homo sapiens]
          Length = 726

 Score =  617 bits (1592), Expect = e-177
 Identities = 350/758 (46%), Positives = 479/758 (63%), Gaps = 51/758 (6%)

Query: 12  SPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEEL 71
           SPPP   P  + YFDR  E++PEY+R RN A DLRQDFN+MEQKKRV+MILQSP+F EEL
Sbjct: 11  SPPP---PQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQSPSFREEL 67

Query: 72  ESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLR 131
           E +IQEQ KKG N + + AL+QIADFM +    V+P +        +M++ M+TP+NDL 
Sbjct: 68  EGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTS--------SMNVSMMTPINDLH 119

Query: 132 GSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSE 191
            +DS+   KGE+L+RCK+++ YRL DL+GW+QL   ++T RV+ EQ+HFLI P G+  SE
Sbjct: 120 TADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSE 179

Query: 192 VTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHIHTPAGAAVSAM 251
           VTASSL+K+N+ G++V++GS+   V+  GF LHSAIYAARPDV+C++H+HTPA AAVSAM
Sbjct: 180 VTASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAM 239

Query: 252 KCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILRNHGLVSVGESV 311
           K GLLP+S  AL +G++AY+D++G +  E +++ +QK LGP  K+L+LRNHG+V++G++V
Sbjct: 240 KWGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALGDTV 299

Query: 312 EEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPVGEGTGSPPKWQ 371
           EEAFY I +L  ACEIQV  L+SAGG +NL+LL  EK++          G   G   K +
Sbjct: 300 EEAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHRPHEVGSVQWAGSTFGPMQKSR 359

Query: 372 IGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYSFASDGDSGTCS 431
           +GE EFEALMRMLDNLGYRTGY YR+P ++EK+K  S+VE+PA+VT + F  DG      
Sbjct: 360 LGEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDG--APVP 417

Query: 432 PLRHSFQKQQREKTRWLNSG----RGDEASEEGQNGSSPKSKTKVWTNITHDHVKPLLQS 487
            LR   QKQQ+EKTRWLN+     R + A E  ++  SP+ KT  W           ++ 
Sbjct: 418 ALRQHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKT-TWMKADE------VEK 470

Query: 488 LSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQNLQDIKT 547
            SSG  +P  I N                PN FVPL T+P+EV EMRNKIREQN QD+K+
Sbjct: 471 SSSG--MPIRIEN----------------PNQFVPLYTDPQEVLEMRNKIREQNRQDVKS 512

Query: 548 AGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYR 607
           AGPQSQ+L  V+ ++S       T S+ + + +         T PNPF+ LTD+ELEEY+
Sbjct: 513 AGPQSQLLASVIAEKSRSPS---TESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYK 569

Query: 608 REVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAAT 667
           +EVERK+   +   + A E+        PA P   P+   + +  LV    + ++    T
Sbjct: 570 KEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKT 629

Query: 668 FKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSA 727
                    P E ++  G  +  +EEE       ++  ++ +     D      + +   
Sbjct: 630 ETSKAATTEP-ETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTD-----VDTSKDK 683

Query: 728 VEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKK 765
            E   +     +GSP KSPSKKKKKFRTPSFLKKSKKK
Sbjct: 684 TESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKK 721


>gi|9257190 adducin 2 isoform e [Homo sapiens]
          Length = 643

 Score =  573 bits (1478), Expect = e-163
 Identities = 316/631 (50%), Positives = 426/631 (67%), Gaps = 51/631 (8%)

Query: 12  SPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEEL 71
           SPPP   P  + YFDR  E++PEY+R RN A DLRQDFN+MEQKKRV+MILQSP+F EEL
Sbjct: 11  SPPP---PQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQSPSFREEL 67

Query: 72  ESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLR 131
           E +IQEQ KKG N + + AL+QIADFM +    V+P +        +M++ M+TP+NDL 
Sbjct: 68  EGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTS--------SMNVSMMTPINDLH 119

Query: 132 GSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSE 191
            +DS+   KGE+L+RCK+++ YRL DL+GW+QL   ++T RV+ EQ+HFLI P G+  SE
Sbjct: 120 TADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSE 179

Query: 192 VTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHIHTPAGAAVSAM 251
           VTASSL+K+N+ G++V++GS+   V+  GF LHSAIYAARPDV+C++H+HTPA AAVSAM
Sbjct: 180 VTASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAM 239

Query: 252 KCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILRNHGLVSVGESV 311
           K GLLP+S  AL +G++AY+D++G +  E +++ +QK LGP  K+L+LRNHG+V++G++V
Sbjct: 240 KWGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALGDTV 299

Query: 312 EEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPVGEGTGSPPKWQ 371
           EEAFY I +L  ACEIQV  L+SAGG +NL+LL  EK++          G   G   K +
Sbjct: 300 EEAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHRPHEVGSVQWAGSTFGPMQKSR 359

Query: 372 IGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYSFASDGDSGTCS 431
           +GE EFEALMRMLDNLGYRTGY YR+P ++EK+K  S+VE+PA+VT + F  DG      
Sbjct: 360 LGEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDG--APVP 417

Query: 432 PLRHSFQKQQREKTRWLNSG----RGDEASEEGQNGSSPKSKTKVWTNITHDHVKPLLQS 487
            LR   QKQQ+EKTRWLN+     R + A E  ++  SP+ KT  W           ++ 
Sbjct: 418 ALRQHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKT-TWMKADE------VEK 470

Query: 488 LSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQNLQDIKT 547
            SSG  +P  I N                PN FVPL T+P+EV EMRNKIREQN QD+K+
Sbjct: 471 SSSG--MPIRIEN----------------PNQFVPLYTDPQEVLEMRNKIREQNRQDVKS 512

Query: 548 AGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYR 607
           AGPQSQ+L  V+ ++S       T S+ + + +         T PNPF+ LTD+ELEEY+
Sbjct: 513 AGPQSQLLASVIAEKSRSPS---TESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYK 569

Query: 608 REVERKQKGSEENLDEAREQKEKSPPDQPAV 638
           +EVERK+      LDE  +++E  P   PAV
Sbjct: 570 KEVERKKL----ELDETGQERE--PGSGPAV 594


>gi|89276787 adducin 2 isoform b [Homo sapiens]
          Length = 559

 Score =  540 bits (1391), Expect = e-153
 Identities = 288/556 (51%), Positives = 386/556 (69%), Gaps = 42/556 (7%)

Query: 12  SPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEEL 71
           SPPP   P  + YFDR  E++PEY+R RN A DLRQDFN+MEQKKRV+MILQSP+F EEL
Sbjct: 11  SPPP---PQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQSPSFREEL 67

Query: 72  ESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLR 131
           E +IQEQ KKG N + + AL+QIADFM +    V+P +        +M++ M+TP+NDL 
Sbjct: 68  EGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTS--------SMNVSMMTPINDLH 119

Query: 132 GSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSE 191
            +DS+   KGE+L+RCK+++ YRL DL+GW+QL   ++T RV+ EQ+HFLI P G+  SE
Sbjct: 120 TADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSE 179

Query: 192 VTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHIHTPAGAAVSAM 251
           VTASSL+K+N+ G++V++GS+   V+  GF LHSAIYAARPDV+C++H+HTPA AAVSAM
Sbjct: 180 VTASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAM 239

Query: 252 KCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILRNHGLVSVGESV 311
           K GLLP+S  AL +G++AY+D++G +  E +++ +QK LGP  K+L+LRNHG+V++G++V
Sbjct: 240 KWGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALGDTV 299

Query: 312 EEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPVGEGTGSPPKWQ 371
           EEAFY I +L  ACEIQV  L+SAGG +NL+LL  EK++          G   G   K +
Sbjct: 300 EEAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHRPHEVGSVQWAGSTFGPMQKSR 359

Query: 372 IGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYSFASDGDSGTCS 431
           +GE EFEALMRMLDNLGYRTGY YR+P ++EK+K  S+VE+PA+VT + F  DG      
Sbjct: 360 LGEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDG--APVP 417

Query: 432 PLRHSFQKQQREKTRWLNSG----RGDEASEEGQNGSSPKSKTKVWTNITHDHVKPLLQS 487
            LR   QKQQ+EKTRWLN+     R + A E  ++  SP+ KT  W           ++ 
Sbjct: 418 ALRQHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKT-TWMKADE------VEK 470

Query: 488 LSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQNLQDIKT 547
            SSG  +P  I N                PN FVPL T+P+EV EMRNKIREQN QD+K+
Sbjct: 471 SSSG--MPIRIEN----------------PNQFVPLYTDPQEVLEMRNKIREQNRQDVKS 512

Query: 548 AGPQSQVLCGVVMDRS 563
           AGPQSQ+L  V+ ++S
Sbjct: 513 AGPQSQLLASVIAEKS 528


>gi|89276790 adducin 2 isoform d [Homo sapiens]
          Length = 253

 Score =  208 bits (530), Expect = 1e-53
 Identities = 110/209 (52%), Positives = 145/209 (69%), Gaps = 11/209 (5%)

Query: 12  SPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEEL 71
           SPPP   P  + YFDR  E++PEY+R RN A DLRQDFN+MEQKKRV+MILQSP+F EEL
Sbjct: 11  SPPP---PQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQSPSFREEL 67

Query: 72  ESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLR 131
           E +IQEQ KKG N + + AL+QIADFM +    V+P +        +M++ M+TP+NDL 
Sbjct: 68  EGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTS--------SMNVSMMTPINDLH 119

Query: 132 GSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSE 191
            +DS+   KGE+L+RCK+++ YRL DL+GW+QL   ++T RV+ EQ+HFLI P G+  SE
Sbjct: 120 TADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSE 179

Query: 192 VTASSLVKINLQGDIVDRGSTNLGVNQAG 220
           VTASSL+K  L+     R      V  AG
Sbjct: 180 VTASSLIKEVLEMRNKIREQNRQDVKSAG 208



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 25/36 (69%), Positives = 31/36 (86%)

Query: 528 KEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRS 563
           KEV EMRNKIREQN QD+K+AGPQSQ+L  V+ ++S
Sbjct: 187 KEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKS 222


>gi|9257180 adducin 2 isoform c [Homo sapiens]
          Length = 420

 Score =  208 bits (530), Expect = 1e-53
 Identities = 110/209 (52%), Positives = 145/209 (69%), Gaps = 11/209 (5%)

Query: 12  SPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEEL 71
           SPPP   P  + YFDR  E++PEY+R RN A DLRQDFN+MEQKKRV+MILQSP+F EEL
Sbjct: 11  SPPP---PQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQSPSFREEL 67

Query: 72  ESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLR 131
           E +IQEQ KKG N + + AL+QIADFM +    V+P +        +M++ M+TP+NDL 
Sbjct: 68  EGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTS--------SMNVSMMTPINDLH 119

Query: 132 GSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSE 191
            +DS+   KGE+L+RCK+++ YRL DL+GW+QL   ++T RV+ EQ+HFLI P G+  SE
Sbjct: 120 TADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSE 179

Query: 192 VTASSLVKINLQGDIVDRGSTNLGVNQAG 220
           VTASSL+K  L+     R      V  AG
Sbjct: 180 VTASSLIKEVLEMRNKIREQNRQDVKSAG 208



 Score =  132 bits (332), Expect = 1e-30
 Identities = 87/238 (36%), Positives = 124/238 (52%), Gaps = 9/238 (3%)

Query: 528 KEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIV 587
           KEV EMRNKIREQN QD+K+AGPQSQ+L  V+ ++S       T S+ + + +       
Sbjct: 187 KEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPS---TESQLMSKGDEDTKDDS 243

Query: 588 STTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPI 647
             T PNPF+ LTD+ELEEY++EVERK+   +   + A E+        PA P   P+   
Sbjct: 244 EETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEA 303

Query: 648 KLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTE 707
           + +  LV    + ++    T         P E ++  G  +  +EEE       ++  ++
Sbjct: 304 ETKSPLVSPSKSLEEGTKKTETSKAATTEP-ETTQPEGVVVNGREEEQTAEEILSKGLSQ 362

Query: 708 ASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKK 765
            +     D      + +    E   +     +GSP KSPSKKKKKFRTPSFLKKSKKK
Sbjct: 363 MTTSADTD-----VDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKK 415


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 53/193 (27%), Positives = 86/193 (44%), Gaps = 17/193 (8%)

Query: 576 IIEKEYQPHVIVSTTGPNPFTT--LTDRELEEYRREVERKQKGSEENLDEAREQKEKSPP 633
           ++EK  +  VIV         T  +T+ E +E + E  ++++G EE   E  E++ KSPP
Sbjct: 446 VVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPP 505

Query: 634 -DQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKE 692
            ++ A P     +P+K E     E  + +  +A   K      SP++            +
Sbjct: 506 AEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEA---KSPAEVKSPEKAKS-------PAK 555

Query: 693 EEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKK 752
           EEA  PP       E +  PA   +P  E+A   A EE  A  P    SP K+ S  K++
Sbjct: 556 EEAKSPPEAKSPEKEEAKSPAEVKSP--EKAKSPAKEE--AKSPAEAKSPEKAKSPVKEE 611

Query: 753 FRTPSFLKKSKKK 765
            ++P+  K   K+
Sbjct: 612 AKSPAEAKSPVKE 624



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 43/158 (27%), Positives = 66/158 (41%), Gaps = 16/158 (10%)

Query: 604  EEYRREVERKQKGSEENLDEAR-EQKEKSPPDQPAVPHPPPSTPIKLE--EDLVPEPTT- 659
            E  + +VE K++ + E   E++ E K++   D+  VP P    P K+E  ED  P+  T 
Sbjct: 868  EAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTE 927

Query: 660  ---GDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDP 716
                +  DA   +P+     P E  EA       KEE+A +   P E P   +     D 
Sbjct: 928  VAKKEPDDAKAKEPS----KPAEKKEAAPEKKDTKEEKAKK---PEEKPKTEAKAKEDDK 980

Query: 717  APVAEEAAPSA--VEEGAAADPGSDGSPGKSPSKKKKK 752
                E + P A   E+ ++ D      P K+   K  K
Sbjct: 981  TLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAK 1018



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 46/172 (26%), Positives = 70/172 (40%), Gaps = 18/172 (10%)

Query: 604 EEYRREVERKQKGSEENLDEAREQK----EKSPPDQPAVPHPPPSTPIKLEEDLVPE-PT 658
           E+ +  ++   K  E+ + +  E K    E+  P +  V  PP     K EE+  P  P 
Sbjct: 797 EKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPK----KAEEEKAPATPK 852

Query: 659 TGDDSDAATFKPTLPDLSPDEPS-EALGFPMLEKEEEAHRPPSPTEAPTEAS-PEP---A 713
           T +  D+   K   P     +P  E    P +EK +E+       EA  +   P P   A
Sbjct: 853 TEEKKDSK--KEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEA 910

Query: 714 PDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKK 765
           P    V E+A P    E A  +P  D +  K PSK  +K       K +K++
Sbjct: 911 PAKVEVKEDAKPKEKTEVAKKEP--DDAKAKEPSKPAEKKEAAPEKKDTKEE 960



 Score = 34.3 bits (77), Expect = 0.45
 Identities = 32/143 (22%), Positives = 52/143 (36%), Gaps = 17/143 (11%)

Query: 609 EVERKQKGSEENLDEARE-QKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAAT 667
           EV+  +K      +EA+  +K KSP  + A       +P+K E     +  +   ++A  
Sbjct: 631 EVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAK- 689

Query: 668 FKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSA 727
                   SP++    +       +EEA  P        E +  P    +PV EEA    
Sbjct: 690 --------SPEKAKSPV-------KEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPE 734

Query: 728 VEEGAAADPGSDGSPGKSPSKKK 750
             +    +        KSP K K
Sbjct: 735 KAKSPVKEEAKSPEKAKSPEKAK 757



 Score = 33.1 bits (74), Expect = 1.00
 Identities = 42/176 (23%), Positives = 61/176 (34%), Gaps = 19/176 (10%)

Query: 607 RREVERKQKGSEENLDEAREQKEKSPPDQPA---VPHPPPSTPIKLEE----DLVPEPTT 659
           + E +  +K      +EA+  ++   P++     V  P   TP K E     D  PE   
Sbjct: 727 KEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAK 786

Query: 660 GD-DSDAATFKPTLPDLSPDEPSEALGFPMLE------KEEEAHRPPSPTEAPTEASPEP 712
                +  + +     L  D  +     P  E      KEEE  +     E P +A  E 
Sbjct: 787 SPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEK 846

Query: 713 APDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKKSDS 768
           AP   P  EE   S  EE     P  +    K   KK+     P   K   KK ++
Sbjct: 847 AP-ATPKTEEKKDSKKEEA----PKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEA 897



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 41/191 (21%), Positives = 71/191 (37%), Gaps = 29/191 (15%)

Query: 600 DRELEEYRREVERKQKGSEENLDEARE-------QKEKSPPDQPAVPHPPPSTPIKLEED 652
           ++E  +   EV+  +K      +EA+        +K KSP  + A       +P+K E  
Sbjct: 568 EKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAK 627

Query: 653 LVPEPTTGDDSDAATF-------KPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAP 705
              E  + + + + T        K   P+    +  E    P+  + +   +  SP +A 
Sbjct: 628 SPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAE 687

Query: 706 TEASPEPAPDP------------APVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKF 753
            + SPE A  P            +PV EEA      +    +        KSP K++ K 
Sbjct: 688 AK-SPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAK- 745

Query: 754 RTPSFLKKSKK 764
            +P   K  +K
Sbjct: 746 -SPEKAKSPEK 755


>gi|30795231 brain abundant, membrane attached signal protein 1
           [Homo sapiens]
          Length = 227

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 48/183 (26%), Positives = 76/183 (41%), Gaps = 12/183 (6%)

Query: 572 ASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKS 631
           A  A  E+E  P          P      +E  +   E + ++K  E++   A+E+  K+
Sbjct: 26  AEGAATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAEEKEGEKDAAAAKEEAPKA 85

Query: 632 PPDQPAVPHPPPSTPIKL--EEDLVPEPTTGDDSDAATFKPTLPDLSP-----DEPSEAL 684
            P++        + P K   +E   P P  G ++  A      P  S      +EPS+  
Sbjct: 86  EPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAESAAPAAGEEPSKEE 145

Query: 685 GFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGK 744
           G P   K+ EA  P +P    T++   PA D  P + EAAPS+ E  AA +  S     +
Sbjct: 146 GEP---KKTEA--PAAPAAQETKSDGAPASDSKPGSSEAAPSSKETPAATEAPSSTPKAQ 200

Query: 745 SPS 747
            P+
Sbjct: 201 GPA 203



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 48/176 (27%), Positives = 71/176 (40%), Gaps = 25/176 (14%)

Query: 604 EEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDS 663
           +E  +E ++K +G+    +   ++ E     +PA        P +  E    E     + 
Sbjct: 16  DEKAKEKDKKAEGAATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAEEKE--GEK 73

Query: 664 DAATFKPTLPDLSPDEP---SEALGFPML--EKEEEAHRPPSPTEAP--TEASPEPAPDP 716
           DAA  K   P   P++    +EA   P    E+E+ A  P +  EAP   EA+  PA   
Sbjct: 74  DAAAAKEEAPKAEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAESA 133

Query: 717 APVAEE---------------AAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPS 757
           AP A E               AAP+A E  +   P SD  PG S +    K  TP+
Sbjct: 134 APAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGAPASDSKPGSSEAAPSSK-ETPA 188



 Score = 33.1 bits (74), Expect = 1.00
 Identities = 33/156 (21%), Positives = 53/156 (33%), Gaps = 25/156 (16%)

Query: 600 DRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPS--TPIKLEEDLVP-- 655
           +++    + E  + +    E   EA+ +  K+P  + A P P      P   E    P  
Sbjct: 72  EKDAAAAKEEAPKAEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAE 131

Query: 656 --------EPTTGDDSDAATFKPTLP----------DLSPDEPSEALGFPMLEKEEEAHR 697
                   EP+  +     T  P  P            S  +P  +   P  ++   A  
Sbjct: 132 SAAPAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGAPASDSKPGSSEAAPSSKETPAATE 191

Query: 698 PPSPT---EAPTEASPEPAPDPAPVAEEAAPSAVEE 730
            PS T   + P  ++ EP P  AP A       V+E
Sbjct: 192 APSSTPKAQGPAASAEEPKPVEAPAANSDQTVTVKE 227


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 37/140 (26%), Positives = 59/140 (42%), Gaps = 2/140 (1%)

Query: 631  SPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAA-TFKPTLPDLSPDEPSEALGFPML 689
            SP   P  P   P++P          PT+   S  + ++ PT P  SP  PS +   P  
Sbjct: 1689 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNY 1748

Query: 690  EKEEEAHRPPSPTEAPTEASPEP-APDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSK 748
                  + P SP+ +PT  S  P +P+  P +   +P++      +   S  SP  SPS 
Sbjct: 1749 SPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSS 1808

Query: 749  KKKKFRTPSFLKKSKKKSDS 768
             +   ++P++   S   S S
Sbjct: 1809 PRYTPQSPTYTPSSPSYSPS 1828



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 37/138 (26%), Positives = 60/138 (43%), Gaps = 2/138 (1%)

Query: 631  SPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAA-TFKPTLPDLSPDEPSEALGFPML 689
            SP   P  P   P++P          PT+ + S  + ++ PT P  SP  PS +   P  
Sbjct: 1752 SPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRY 1811

Query: 690  EKEEEAHRPPSPTEAPTEASPEP-APDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSK 748
              +   + P SP+ +P+  S  P +P   P +   +PS+ E    +   S  SP  SP+ 
Sbjct: 1812 TPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTS 1871

Query: 749  KKKKFRTPSFLKKSKKKS 766
             K    +P++   + K S
Sbjct: 1872 PKYSPTSPTYSPTTPKYS 1889



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 36/138 (26%), Positives = 57/138 (41%), Gaps = 2/138 (1%)

Query: 631  SPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAA-TFKPTLPDLSPDEPSEALGFPML 689
            SP   P  P   P++P          PT+   S  + ++ PT P  SP  PS +   P  
Sbjct: 1633 SPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1692

Query: 690  EKEEEAHRPPSPTEAPTEASPEP-APDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSK 748
                 ++ P SP+ +PT  S  P +P  +P +   +P++      +   S  SP  SP+ 
Sbjct: 1693 SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTS 1752

Query: 749  KKKKFRTPSFLKKSKKKS 766
                  +PS+   S   S
Sbjct: 1753 PNYTPTSPSYSPTSPSYS 1770



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 35/140 (25%), Positives = 56/140 (40%), Gaps = 8/140 (5%)

Query: 633  PDQPAVPHP-----PPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFP 687
            P  P +P P     P  +P     +  P    G    + ++ PT P  SP  PS +   P
Sbjct: 1577 PSSPYIPSPGGAMSPSYSPTSPAYE--PRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSP 1634

Query: 688  MLEKEEEAHRPPSPTEAPTEASPEP-APDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSP 746
                   ++ P SP+ +PT  S  P +P  +P +   +P++      +   S  SP  SP
Sbjct: 1635 NYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1694

Query: 747  SKKKKKFRTPSFLKKSKKKS 766
            +       +PS+   S   S
Sbjct: 1695 TSPSYSPTSPSYSPTSPSYS 1714



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 36/140 (25%), Positives = 55/140 (39%), Gaps = 2/140 (1%)

Query: 631  SPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAA-TFKPTLPDLSPDEPSEALGFPML 689
            SP   P  P   P++P          PT+   S  +  + PT P+ +P  PS +   P  
Sbjct: 1710 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSY 1769

Query: 690  EKEEEAHRPPSPTEAPTEASPEP-APDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSK 748
                  + P SP  +PT  S  P +P  +P +   +PS+      +   +  SP  SPS 
Sbjct: 1770 SPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSS 1829

Query: 749  KKKKFRTPSFLKKSKKKSDS 768
                  +P +   S   S S
Sbjct: 1830 PSYSPTSPKYTPTSPSYSPS 1849



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 31/130 (23%), Positives = 56/130 (43%), Gaps = 2/130 (1%)

Query: 631  SPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAA-TFKPTLPDLSPDEPSEALGFPML 689
            SP   P  P+  P++P          PT+   S  + ++ P+ P  +P  P+     P  
Sbjct: 1766 SPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSY 1825

Query: 690  EKEEEAHRPPSPTEAPTEASPEPA-PDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSK 748
                 ++ P SP   PT  S  P+ P+  P + + +P++ +    +   S  SP  SP+ 
Sbjct: 1826 SPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTT 1885

Query: 749  KKKKFRTPSF 758
             K    +P++
Sbjct: 1886 PKYSPTSPTY 1895



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 34/128 (26%), Positives = 56/128 (43%), Gaps = 11/128 (8%)

Query: 631  SPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAA-TFKPTLPDLSPDEPSEALGFPML 689
            SP   P+ P   P++P          PT+   S  + T+ PT P  SP  P+ +   P+ 
Sbjct: 1843 SPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVY 1902

Query: 690  EKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKK 749
                  + P SPT +PT      +P  +P +   +P++  +G+   P    SPG SP+  
Sbjct: 1903 TPTSPKYSPTSPTYSPT------SPKYSPTSPTYSPTS-PKGSTYSP---TSPGYSPTSP 1952

Query: 750  KKKFRTPS 757
                 +P+
Sbjct: 1953 TYSLTSPA 1960



 Score = 37.0 bits (84), Expect = 0.069
 Identities = 28/112 (25%), Positives = 39/112 (34%), Gaps = 1/112 (0%)

Query: 626  EQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAA-TFKPTLPDLSPDEPSEAL 684
            E    SP   P  P   P++P          PTT   S  + T+ PT P  +P  P  + 
Sbjct: 1852 EYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSP 1911

Query: 685  GFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADP 736
              P        + P SPT +PT          +P     +P+      A  P
Sbjct: 1912 TSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISP 1963


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 51/166 (30%), Positives = 70/166 (42%), Gaps = 33/166 (19%)

Query: 608  REVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIK--------LEEDLVPEPTT 659
            + V RK+   EE      E K+     +PAVP PPP  P++          E  +PEPT 
Sbjct: 4645 KSVLRKRPEEEE---PKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPT- 4700

Query: 660  GDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPV 719
                     KP +P L   EP      P  E E +  +PP P E      PEP P  APV
Sbjct: 4701 ----KVPEIKPAIP-LPAPEPK-----PKPEAEVKTIKPP-PVE------PEPTPIAAPV 4743

Query: 720  AEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKK 765
                 P   ++  A  P  + +  K P K   K +TPS ++  ++K
Sbjct: 4744 ---TVPVVGKKAEAKAPKEEAAKPKGPIKGVPK-KTPSPIEAERRK 4785


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 51/166 (30%), Positives = 70/166 (42%), Gaps = 33/166 (19%)

Query: 608  REVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIK--------LEEDLVPEPTT 659
            + V RK+   EE      E K+     +PAVP PPP  P++          E  +PEPT 
Sbjct: 4578 KSVLRKRPEEEE---PKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPT- 4633

Query: 660  GDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPV 719
                     KP +P L   EP      P  E E +  +PP P E      PEP P  APV
Sbjct: 4634 ----KVPEIKPAIP-LPAPEPK-----PKPEAEVKTIKPP-PVE------PEPTPIAAPV 4676

Query: 720  AEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKK 765
                 P   ++  A  P  + +  K P K   K +TPS ++  ++K
Sbjct: 4677 ---TVPVVGKKAEAKAPKEEAAKPKGPIKGVPK-KTPSPIEAERRK 4718


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 51/166 (30%), Positives = 70/166 (42%), Gaps = 33/166 (19%)

Query: 608  REVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIK--------LEEDLVPEPTT 659
            + V RK+   EE      E K+     +PAVP PPP  P++          E  +PEPT 
Sbjct: 4453 KSVLRKRPEEEE---PKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPT- 4508

Query: 660  GDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPV 719
                     KP +P L   EP      P  E E +  +PP P E      PEP P  APV
Sbjct: 4509 ----KVPEIKPAIP-LPAPEPK-----PKPEAEVKTIKPP-PVE------PEPTPIAAPV 4551

Query: 720  AEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKK 765
                 P   ++  A  P  + +  K P K   K +TPS ++  ++K
Sbjct: 4552 ---TVPVVGKKAEAKAPKEEAAKPKGPIKGVPK-KTPSPIEAERRK 4593


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
           sapiens]
          Length = 2462

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 45/149 (30%), Positives = 55/149 (36%), Gaps = 19/149 (12%)

Query: 627 QKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGF 686
           Q    PP       PPP  P    ED +P PT    +  AT  PT P   P   +     
Sbjct: 747 QNGPKPPATLGADGPPPGPPTPPPED-IPAPTEPTPASEATGAPTPPPAPPSPSAPPPVV 805

Query: 687 PMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADP-------GSD 739
           P  EKEEE    P     P E   E  P   P AEE    AV+ G A +P        ++
Sbjct: 806 PKEEKEEETAAAP-----PVEEGEEQKP---PAAEEL---AVDTGKAEEPVKSECTEEAE 854

Query: 740 GSPGKSPSKKKKKFRTPSFLKKSKKKSDS 768
             P K    +  +      LK  KK+  S
Sbjct: 855 EGPAKGKDAEAAEATAEGALKAEKKEGGS 883



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 10/112 (8%)

Query: 628  KEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFP 687
            +E + P +PA P PPP   ++ E D   +P  G      +  P  P  +  E  + + FP
Sbjct: 969  REDAAPTKPAPPAPPPPQNLQPESDAPQQP--GSSPRGKSRSPAPP--ADKEAEKPVFFP 1024

Query: 688  MLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGA--AADPG 737
                E +      P + P   S  P P P     +A+P A +  A   A PG
Sbjct: 1025 AFAAEAQ----KLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPG 1072



 Score = 33.1 bits (74), Expect = 1.00
 Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 17/128 (13%)

Query: 652  DLVPEPTTGDDSDAATFKPTLPDLSPD-----EPSEALGFPMLEKEEEA---------HR 697
            D V E   GD +   + +P+L   + D      P + L    L++   A         H 
Sbjct: 907  DEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIQVTKVHE 966

Query: 698  PPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKK-KKKFRTP 756
            PP    APT+ +P PAP P P   +    A ++  ++  G   SP     K+ +K    P
Sbjct: 967  PPREDAAPTKPAP-PAP-PPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFP 1024

Query: 757  SFLKKSKK 764
            +F  +++K
Sbjct: 1025 AFAAEAQK 1032


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
           sapiens]
          Length = 2524

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 45/149 (30%), Positives = 55/149 (36%), Gaps = 19/149 (12%)

Query: 627 QKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGF 686
           Q    PP       PPP  P    ED +P PT    +  AT  PT P   P   +     
Sbjct: 764 QNGPKPPATLGADGPPPGPPTPPPED-IPAPTEPTPASEATGAPTPPPAPPSPSAPPPVV 822

Query: 687 PMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADP-------GSD 739
           P  EKEEE    P     P E   E  P   P AEE    AV+ G A +P        ++
Sbjct: 823 PKEEKEEETAAAP-----PVEEGEEQKP---PAAEEL---AVDTGKAEEPVKSECTEEAE 871

Query: 740 GSPGKSPSKKKKKFRTPSFLKKSKKKSDS 768
             P K    +  +      LK  KK+  S
Sbjct: 872 EGPAKGKDAEAAEATAEGALKAEKKEGGS 900



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 10/112 (8%)

Query: 628  KEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFP 687
            +E + P +PA P PPP   ++ E D   +P  G      +  P  P  +  E  + + FP
Sbjct: 985  REDAAPTKPAPPAPPPPQNLQPESDAPQQP--GSSPRGKSRSPAPP--ADKEAEKPVFFP 1040

Query: 688  MLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGA--AADPG 737
                E +      P + P   S  P P P     +A+P A +  A   A PG
Sbjct: 1041 AFAAEAQ----KLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPG 1088



 Score = 33.5 bits (75), Expect = 0.76
 Identities = 33/127 (25%), Positives = 54/127 (42%), Gaps = 16/127 (12%)

Query: 652  DLVPEPTTGDDSDAATFKPTLPDLSPD-----EPSEALGFPMLEKEEEA--------HRP 698
            D V E   GD +   + +P+L   + D      P + L    L++   A        H P
Sbjct: 924  DEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEP 983

Query: 699  PSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKK-KKKFRTPS 757
            P    APT+ +P PAP P P   +    A ++  ++  G   SP     K+ +K    P+
Sbjct: 984  PREDAAPTKPAP-PAP-PPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPA 1041

Query: 758  FLKKSKK 764
            F  +++K
Sbjct: 1042 FAAEAQK 1048


>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
          Length = 1271

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 41/137 (29%), Positives = 58/137 (42%), Gaps = 21/137 (15%)

Query: 626 EQKEKSP-PDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEAL 684
           EQ  +SP P  P  P PPP  P        P P    ++         P+L+P    EA 
Sbjct: 18  EQPAESPEPPPPWPPPPPPPAP-------PPAPPLLSEASPEPIPEPCPELAPGPCPEAT 70

Query: 685 GFPMLEKEEEAHRPPSP---TEAPTEASPEPAPDPAP-VAEEAAPSAVEEGAAADPGSDG 740
                E   E +  P+P   TE  +E +PEPA +PAP  A E AP       A +P ++ 
Sbjct: 71  S----ESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPE-----PAPEPATES 121

Query: 741 SPGKSPSKKKKKFRTPS 757
           +P  +P    +    P+
Sbjct: 122 APEPTPEPALESVPEPA 138



 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 47/157 (29%), Positives = 59/157 (37%), Gaps = 28/157 (17%)

Query: 617 SEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLS 676
           +E   + A E   +  P+    P P P+T    E    PEP T + +   T +P L   S
Sbjct: 79  TEPTPEPATEPASEPAPEPATEPAPEPATEPAPEP--APEPAT-ESAPEPTPEPALE--S 133

Query: 677 PDEPSEALGFPMLEKEEEAHRPPSPTEAPT---------EASPEPAPDPAPVAEEAAPSA 727
             EP+     P L  E      P PT  P          EA+PE  P PAP   +     
Sbjct: 134 VPEPA-----PELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDT 188

Query: 728 VEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKK 764
            E G    P    SP  SPS      RTP    + KK
Sbjct: 189 RERGLKTSP----SPSPSPSP-----RTPMSWSRIKK 216



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 31/96 (32%), Positives = 43/96 (44%), Gaps = 17/96 (17%)

Query: 662 DSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAP---TEASPEPAPDPAP 718
           D  AA  + T P    ++P+E+   P          PP+P  AP   +EASPEP P+P P
Sbjct: 2   DRGAAAAQGTAPPQDGEQPAESPEPP--PPWPPPPPPPAPPPAPPLLSEASPEPIPEPCP 59

Query: 719 -VAEEAAPSAVEEGA-----------AADPGSDGSP 742
            +A    P A  E A           A +P S+ +P
Sbjct: 60  ELAPGPCPEATSESATELYTEPTPEPATEPASEPAP 95


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 49/191 (25%), Positives = 76/191 (39%), Gaps = 24/191 (12%)

Query: 594 PFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKS-------PPDQPAVPHPPPSTP 646
           P TT T R       E   KQ  S    D+ +++KEKS       P      P PP  TP
Sbjct: 313 PGTTSTQRPSSP---ETATKQPSSPYE-DKDKDKKEKSATRPSPSPERSSTGPEPPAPTP 368

Query: 647 IKLE------EDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPS 700
           +  E      + L   P + +  +  +      D SP +  E L  P     E +   P 
Sbjct: 369 LLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKL--PQSSSSESSPPSPQ 426

Query: 701 PTEAPTEAS-----PEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRT 755
           PT+    AS     P+PAP P    E ++    +  +      D S   +PS++  + R+
Sbjct: 427 PTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRS 486

Query: 756 PSFLKKSKKKS 766
           P+  K+ + +S
Sbjct: 487 PATAKRGRSRS 497



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 37/152 (24%), Positives = 55/152 (36%), Gaps = 19/152 (12%)

Query: 636  PAVPH-----PPPST------------PIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPD 678
            P VPH     PP ST            P K         ++   S +++   +    S  
Sbjct: 2499 PGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGS 2558

Query: 679  EPSEALGFPM-LEKEEEAHRPPSPTEAPTEASPE-PAPDPAPVAEEAAPSAVEEGAAADP 736
              S++ G  + ++ E    R PSPT AP EA  E   P+P P   +   S+    +++  
Sbjct: 2559 SSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSS 2618

Query: 737  GSDGSPGKSPSKKKKKFRTPSFLKKSKKKSDS 768
             S  S   S S       + S    S   S S
Sbjct: 2619 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 4/77 (5%)

Query: 690 EKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKK 749
           E ++ A  PP P     E+S   +P P    ++          ++ P  +    +  S K
Sbjct: 159 EAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRE----RKKSSK 214

Query: 750 KKKFRTPSFLKKSKKKS 766
           KKK R+ S  KK K +S
Sbjct: 215 KKKHRSESESKKRKHRS 231



 Score = 30.8 bits (68), Expect = 5.0
 Identities = 42/193 (21%), Positives = 72/193 (37%), Gaps = 46/193 (23%)

Query: 602  ELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAV-----------PHPPPSTPIKLE 650
            E+++  R   R Q GS    D + E K  +P   P             P P  S+  +  
Sbjct: 1603 EVKDKPRAAPRAQSGS----DSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESS 1658

Query: 651  EDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEK---------------EEEA 695
             +  P+  T      ++ +P     +P     +   P L +               E  +
Sbjct: 1659 PEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRS 1718

Query: 696  HRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSP--GKSPSKKKKKF 753
              PP    +P+ +SPEPA        E + S+    +A+ P +  +   G+SPS K    
Sbjct: 1719 RTPPRHRRSPSVSSPEPA--------EKSRSSRRRRSASSPRTKTTSRRGRSPSPK---- 1766

Query: 754  RTPSFLKKSKKKS 766
              P  L++S+ +S
Sbjct: 1767 --PRGLQRSRSRS 1777


>gi|22325356 PALM2-AKAP2 protein isoform 2 [Homo sapiens]
          Length = 1090

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 76/337 (22%), Positives = 125/337 (37%), Gaps = 40/337 (11%)

Query: 432 PLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDHVKPLLQSLSSG 491
           P   +  +Q        NS     A  E  NG SP            D +   LQ   S 
Sbjct: 333 PTERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQP--------RDALGDSLQVPVS- 383

Query: 492 VCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNT---NPKEVQEMRNKIREQNLQDIKTA 548
              PS  T+   +  DG  T T+        L     + K  +   +   E+    I+  
Sbjct: 384 ---PSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKV 440

Query: 549 GPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTT---LTDRELEE 605
            P  ++L      R L++ + V  +  I  K + P        P   T    L +  LE 
Sbjct: 441 RPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNP--------PQEKTIEEQLDEEHLES 492

Query: 606 YRREVERKQKGSEEN---LDEAREQKEKSPPDQ----PAVPHPPPSTPIKLEEDLVPEPT 658
           +++  ERK++ +++    L +  +Q+++ PP Q    PA  H   S   K +ED+V E  
Sbjct: 493 HKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQI 552

Query: 659 TGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAP 718
              D  AA  +  L + S    ++    P L   +  +RP     +    +    P    
Sbjct: 553 ---DFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGG 609

Query: 719 VAEEAAPSAVE----EGAAADPGSDGSPGKSPSKKKK 751
             E++  SA +     GA   P + GS G + S+ K+
Sbjct: 610 PPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKE 646



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 24/103 (23%), Positives = 43/103 (41%), Gaps = 3/103 (2%)

Query: 580 EYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVP 639
           EYQ  ++V            D+ + +  R+   +Q+G E  ++EA      S   Q    
Sbjct: 798 EYQAGLLVQNAIQQAIAEQVDKAVSKTSRD-GAEQQGPEATVEEAEAAAFGSEKPQSMFE 856

Query: 640 HPPPSTPIKLEEDLVPEPTTGDDSDAATFKP--TLPDLSPDEP 680
            P  S+P++ + D++P+    +D       P   LP + P  P
Sbjct: 857 PPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSGP 899


>gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens]
          Length = 1103

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 76/337 (22%), Positives = 125/337 (37%), Gaps = 40/337 (11%)

Query: 432 PLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDHVKPLLQSLSSG 491
           P   +  +Q        NS     A  E  NG SP            D +   LQ   S 
Sbjct: 333 PTERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQP--------RDALGDSLQVPVS- 383

Query: 492 VCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNT---NPKEVQEMRNKIREQNLQDIKTA 548
              PS  T+   +  DG  T T+        L     + K  +   +   E+    I+  
Sbjct: 384 ---PSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKV 440

Query: 549 GPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTT---LTDRELEE 605
            P  ++L      R L++ + V  +  I  K + P        P   T    L +  LE 
Sbjct: 441 RPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNP--------PQEKTIEEQLDEEHLES 492

Query: 606 YRREVERKQKGSEEN---LDEAREQKEKSPPDQ----PAVPHPPPSTPIKLEEDLVPEPT 658
           +++  ERK++ +++    L +  +Q+++ PP Q    PA  H   S   K +ED+V E  
Sbjct: 493 HKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQI 552

Query: 659 TGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAP 718
              D  AA  +  L + S    ++    P L   +  +RP     +    +    P    
Sbjct: 553 ---DFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGG 609

Query: 719 VAEEAAPSAVE----EGAAADPGSDGSPGKSPSKKKK 751
             E++  SA +     GA   P + GS G + S+ K+
Sbjct: 610 PPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKE 646



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 24/103 (23%), Positives = 43/103 (41%), Gaps = 3/103 (2%)

Query: 580 EYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVP 639
           EYQ  ++V            D+ + +  R+   +Q+G E  ++EA      S   Q    
Sbjct: 798 EYQAGLLVQNAIQQAIAEQVDKAVSKTSRD-GAEQQGPEATVEEAEAAAFGSEKPQSMFE 856

Query: 640 HPPPSTPIKLEEDLVPEPTTGDDSDAATFKP--TLPDLSPDEP 680
            P  S+P++ + D++P+    +D       P   LP + P  P
Sbjct: 857 PPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSGP 899


>gi|211971074 A kinase (PRKA) anchor protein 2 isoform 2 [Homo
           sapiens]
          Length = 859

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 76/337 (22%), Positives = 125/337 (37%), Gaps = 40/337 (11%)

Query: 432 PLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDHVKPLLQSLSSG 491
           P   +  +Q        NS     A  E  NG SP            D +   LQ   S 
Sbjct: 102 PTERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQP--------RDALGDSLQVPVS- 152

Query: 492 VCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNT---NPKEVQEMRNKIREQNLQDIKTA 548
              PS  T+   +  DG  T T+        L     + K  +   +   E+    I+  
Sbjct: 153 ---PSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKV 209

Query: 549 GPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTT---LTDRELEE 605
            P  ++L      R L++ + V  +  I  K + P        P   T    L +  LE 
Sbjct: 210 RPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNP--------PQEKTIEEQLDEEHLES 261

Query: 606 YRREVERKQKGSEEN---LDEAREQKEKSPPDQ----PAVPHPPPSTPIKLEEDLVPEPT 658
           +++  ERK++ +++    L +  +Q+++ PP Q    PA  H   S   K +ED+V E  
Sbjct: 262 HKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQI 321

Query: 659 TGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAP 718
              D  AA  +  L + S    ++    P L   +  +RP     +    +    P    
Sbjct: 322 ---DFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGG 378

Query: 719 VAEEAAPSAVE----EGAAADPGSDGSPGKSPSKKKK 751
             E++  SA +     GA   P + GS G + S+ K+
Sbjct: 379 PPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKE 415



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 24/103 (23%), Positives = 43/103 (41%), Gaps = 3/103 (2%)

Query: 580 EYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVP 639
           EYQ  ++V            D+ + +  R+   +Q+G E  ++EA      S   Q    
Sbjct: 567 EYQAGLLVQNAIQQAIAEQVDKAVSKTSRD-GAEQQGPEATVEEAEAAAFGSEKPQSMFE 625

Query: 640 HPPPSTPIKLEEDLVPEPTTGDDSDAATFKP--TLPDLSPDEP 680
            P  S+P++ + D++P+    +D       P   LP + P  P
Sbjct: 626 PPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSGP 668


>gi|51873058 A kinase (PRKA) anchor protein 2 isoform 1 [Homo
           sapiens]
          Length = 948

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 76/337 (22%), Positives = 125/337 (37%), Gaps = 40/337 (11%)

Query: 432 PLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDHVKPLLQSLSSG 491
           P   +  +Q        NS     A  E  NG SP            D +   LQ   S 
Sbjct: 191 PTERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQP--------RDALGDSLQVPVS- 241

Query: 492 VCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNT---NPKEVQEMRNKIREQNLQDIKTA 548
              PS  T+   +  DG  T T+        L     + K  +   +   E+    I+  
Sbjct: 242 ---PSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKV 298

Query: 549 GPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTT---LTDRELEE 605
            P  ++L      R L++ + V  +  I  K + P        P   T    L +  LE 
Sbjct: 299 RPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNP--------PQEKTIEEQLDEEHLES 350

Query: 606 YRREVERKQKGSEEN---LDEAREQKEKSPPDQ----PAVPHPPPSTPIKLEEDLVPEPT 658
           +++  ERK++ +++    L +  +Q+++ PP Q    PA  H   S   K +ED+V E  
Sbjct: 351 HKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQI 410

Query: 659 TGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAP 718
              D  AA  +  L + S    ++    P L   +  +RP     +    +    P    
Sbjct: 411 ---DFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGG 467

Query: 719 VAEEAAPSAVE----EGAAADPGSDGSPGKSPSKKKK 751
             E++  SA +     GA   P + GS G + S+ K+
Sbjct: 468 PPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKE 504



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 24/103 (23%), Positives = 43/103 (41%), Gaps = 3/103 (2%)

Query: 580 EYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVP 639
           EYQ  ++V            D+ + +  R+   +Q+G E  ++EA      S   Q    
Sbjct: 656 EYQAGLLVQNAIQQAIAEQVDKAVSKTSRD-GAEQQGPEATVEEAEAAAFGSEKPQSMFE 714

Query: 640 HPPPSTPIKLEEDLVPEPTTGDDSDAATFKP--TLPDLSPDEP 680
            P  S+P++ + D++P+    +D       P   LP + P  P
Sbjct: 715 PPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSGP 757


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 47/168 (27%), Positives = 67/168 (39%), Gaps = 28/168 (16%)

Query: 600  DRELEEYRREVERKQKGSEENLDEARE--------QKEKSPPDQPAVPH--PPPSTPIKL 649
            + E  E   E E + +  EE L+E  +        + E+  P  P +P   PPP +P K+
Sbjct: 936  EEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKV 995

Query: 650  EEDLVPEPT---------TGDDSDAATFKPTLPDLSPDE-------PSEALGFPMLEK-E 692
            + +  PEP          T ++  A T     P+  P +        S A G P  E  E
Sbjct: 996  QPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVE 1055

Query: 693  EEAHRPPSPTEAPTE-ASPEPAPDPAPVAEEAAPSAVEEGAAADPGSD 739
            EE   PP+  E  TE  S +  P P   AEE   +  E  A  +   D
Sbjct: 1056 EEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQD 1103



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 39/153 (25%), Positives = 64/153 (41%), Gaps = 19/153 (12%)

Query: 600  DRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTT 659
            + E EE   E E +++  EE+ +E  E +E+   ++            + EE+   E   
Sbjct: 889  EEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEE-------EFEEEFEEEEGE 941

Query: 660  GDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPS------PTEAPTEASPEPA 713
             ++ +    +    +L   E  E  G    E EE A  PP+      P E+P +  PEP 
Sbjct: 942  LEEEEEEEDEEEEEELEEVEDLE-FGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPE 1000

Query: 714  PDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSP 746
            P+P  + E   P   EE      G+D +P  +P
Sbjct: 1001 PEPGLLLEVEEPGTEEE-----RGADTAPTLAP 1028



 Score = 37.4 bits (85), Expect = 0.053
 Identities = 40/125 (32%), Positives = 43/125 (34%), Gaps = 17/125 (13%)

Query: 632 PPDQP---AVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPT-LPDLSPDEPSEALGFP 687
           PPD+     VP P      K E   V      D  D+    P  LP L P  PS A   P
Sbjct: 751 PPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPP 810

Query: 688 MLEKEEEAHRPPSPT-EAPTEAS------PEPAPDPAPVAEEAA---PSAVEEGAAADPG 737
           +         PP P  E P E        P P P P PV        P  V EG    PG
Sbjct: 811 IAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGT---PG 867

Query: 738 SDGSP 742
             G P
Sbjct: 868 GGGPP 872



 Score = 31.2 bits (69), Expect = 3.8
 Identities = 22/96 (22%), Positives = 37/96 (38%), Gaps = 10/96 (10%)

Query: 617  SEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDL---------VPEPTTGDDSDAAT 667
            S+  ++   E     PP Q  V   P + P  LEE+           PE    ++ +  T
Sbjct: 1033 SQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETET 1092

Query: 668  FKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTE 703
                L +   D+ +  L    ++   +  +PP PTE
Sbjct: 1093 EAEALQEKEQDDTAAMLA-DFIDCPPDDEKPPPPTE 1127


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 38/141 (26%), Positives = 54/141 (38%), Gaps = 10/141 (7%)

Query: 628 KEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFP 687
           K++SPP  P   + PP  P K  E +V  P+  + ++     P  P   P  P E     
Sbjct: 725 KDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEE----- 779

Query: 688 MLEKEEEAHRPPSPTEAPTEASPEPA-PDPAP--VAEEAAPSAVEEGAAADPGSDGSPGK 744
             +    A  PP      + ASPEPA P  +P  V+  AA S+        P     P  
Sbjct: 780 --QDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPP 837

Query: 745 SPSKKKKKFRTPSFLKKSKKK 765
           +P         P  + K  +K
Sbjct: 838 APPAPAPASSAPGHVAKLPQK 858



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 35/120 (29%), Positives = 51/120 (42%), Gaps = 14/120 (11%)

Query: 632 PPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEK 691
           PP +P  P+P  + P      +VP P +   +DA+   P  P  +     E+   P++ K
Sbjct: 673 PPSKPRSPNP--AAPALAAPAVVPGPVS--TTDASPQSPPTPQTTLTPLQES---PVISK 725

Query: 692 EEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVE--EGAAADPGSDGSPGKSPSKK 749
           ++    PPSP   P    P P P   P     APSA E  E    DP     P  +P ++
Sbjct: 726 DQSP--PPSP---PPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQ 780


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 47/163 (28%), Positives = 69/163 (42%), Gaps = 27/163 (16%)

Query: 608   REVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKL-----EEDLVPEPTTGDD 662
             + V RK+   EE   E ++ ++   P  P  P P P   +++      E  +PEPT    
Sbjct: 10950 KSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPT---- 11005

Query: 663   SDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEE 722
                   KP +P L   EP      P  E E +  +PP P E      PEP P  APV   
Sbjct: 11006 -KVPEIKPAIP-LPAPEPK-----PKPEAEVKTIKPP-PVE------PEPTPIAAPV--- 11048

Query: 723   AAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKK 765
               P   ++  A  P  + +  K P K   K +TPS ++  ++K
Sbjct: 11049 TVPVVGKKAEAKAPKEEAAKPKGPIKGVPK-KTPSPIEAERRK 11090



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 50/190 (26%), Positives = 76/190 (40%), Gaps = 21/190 (11%)

Query: 568   ELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQ 627
             E+V   K  +    +P V  +     P   + ++++ E    +  K +     + EA ++
Sbjct: 10531 EVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPE---AIPPKPESPPPEVPEAPKE 10587

Query: 628   --KEKSPPDQPAVPHPPPSTPIKLEE---DLVPEPTTGDDSDAATFKPTLPDLSPDEPSE 682
                EK  P  P  P  P  TP+K+ E   ++VPE             P  P++ P +  E
Sbjct: 10588 VVPEKKVPAAP--PKKPEVTPVKVPEAPKEVVPE------KKVPVPPPKKPEVPPTKVPE 10639

Query: 683   ALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPS-AVEEGAAADPGSDGS 741
                  + EK+     PP P   P    PE   +P  VA E  P+  VEE   A P     
Sbjct: 10640 VPKVAVPEKKVPEAIPPKPESPP----PEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTV 10695

Query: 742   PGKSPSKKKK 751
             P K P  +KK
Sbjct: 10696 PPKKPVPEKK 10705



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 40/154 (25%), Positives = 61/154 (39%), Gaps = 11/154 (7%)

Query: 618   EENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSP 677
             +E + E +    K P   PA     P  P+  E+  VP P   +      ++    +++P
Sbjct: 10754 KEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEP-EEIAP 10812

Query: 678   DE---PSEALGFPMLEKEEEAHRPPSPTEAPTEASPEP-----APDPAPVAEEAAPSAVE 729
             +E   P E    P+ E+EE    PP+  E P +  PE          AP  +E  P  V 
Sbjct: 10813 EEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVI 10872

Query: 730   EGAAADPGSDGSPGKSPSK--KKKKFRTPSFLKK 761
             E     P     P   P +  K+K F+  +  KK
Sbjct: 10873 EKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKK 10906



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 40/141 (28%), Positives = 58/141 (41%), Gaps = 20/141 (14%)

Query: 628   KEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFP 687
             ++K P   P  P  PP+   ++ +++VPE             P  P++ P +  E    P
Sbjct: 10731 EKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVA--------VPKKPEVPPAKVPEVPKKP 10782

Query: 688   MLEKE------EEAHRPPSPT-EAPTEASPEP--APD---PAPVAEEAAPSAVEEGAAAD 735
             +LE++      E A  PP    E P E +PE   AP+   P PVAEE  P         +
Sbjct: 10783 VLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEE 10842

Query: 736   PGSDGSPGKSPSKKKKKFRTP 756
             P       K P  KK +   P
Sbjct: 10843 PKKIIPEKKVPVIKKPEAPPP 10863



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 39/137 (28%), Positives = 58/137 (42%), Gaps = 12/137 (8%)

Query: 595  FTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLV 654
            F + T+ E+     EV+ K+  +EE +  A  ++ + PP  P +P  P        E++ 
Sbjct: 9249 FASHTEEEVSVTVPEVQ-KEIVTEEKIHVAISKRVEPPPKVPELPEKPAP------EEVA 9301

Query: 655  PEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPA- 713
            P P        A   P +P      P E    P+ +KE  A  PP   E P +  PE   
Sbjct: 9302 PVPIPKKVEPPAPKVPEVP--KKPVPEEKKPVPVPKKEPAA--PPKVPEVPKKPVPEEKI 9357

Query: 714  PDPAPVAEEAAPSAVEE 730
            P P    +EA P+ V E
Sbjct: 9358 PVPVAKKKEAPPAKVPE 9374



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 57/219 (26%), Positives = 88/219 (40%), Gaps = 33/219 (15%)

Query: 559   VMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTDR-ELEEYRREVERKQKGS 617
             V+ +  ++ E+V A    I +E + H +        F  + +  +LE++R E E + +  
Sbjct: 10359 VVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKV 10418

Query: 618   EENLD--EARE----QKEKSPPDQPAV------PHPPPST-------PIKLEEDLVPEPT 658
                ++  EA E    +K K+PP  P +      P  PP+        P K+ E  VP+  
Sbjct: 10419 HRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPE--VPKKI 10476

Query: 659   TGDDSDAATFKPTLPD------LSPDE--PSEALGFPMLEKEEEAHRPPSPTEAPTEASP 710
               ++      +P +P       L P E  P + +  P  +K E    PP   EAP E  P
Sbjct: 10477 VVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAP--PPKVPEAPKEVVP 10534

Query: 711   E-PAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSK 748
             E   P P P   E  P+ V E   A       P   P K
Sbjct: 10535 EKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPK 10573



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 41/162 (25%), Positives = 63/162 (38%), Gaps = 20/162 (12%)

Query: 602   ELEEYRREVERKQKGSEENLDEARE---QKEKSPPDQPAVPHPPPSTPIKLEEDLVPE-- 656
             E EE   E E      EE L E  E   ++E+ PP++  VP      P   EE+++PE  
Sbjct: 10122 EEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVP---EEEVLPEVK 10178

Query: 657   -------PTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEAS 709
                    P           K  +P      P++    P   +E+    P      P E +
Sbjct: 10179 PKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVT 10238

Query: 710   PEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKK 751
              E  P+  P++EE  P   EE  + +   + +P + P   KK
Sbjct: 10239 EE--PEEEPISEEEIP---EEPPSIEEVEEVAPPRVPEVIKK 10275



 Score = 36.6 bits (83), Expect = 0.090
 Identities = 43/155 (27%), Positives = 58/155 (37%), Gaps = 17/155 (10%)

Query: 609   EVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPS-TPIKLEEDLVPEPTTGDDSDAAT 667
             EV RK    E+      ++KE  P   P VP  P    P+ + +   P P          
Sbjct: 9952  EVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAK-------- 10003

Query: 668   FKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEP-APDPAPVAEEAAPS 726
               P +P      P E +  P+ +K E    P    E P +  PE   P PAP   EA P+
Sbjct: 10004 -VPEVP--KKPVPEEKVPVPVPKKVEAP--PAKVPEVPKKPVPEKKVPVPAPKKVEAPPA 10058

Query: 727   AVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKK 761
              V E        +  P  +P  KK +   P   KK
Sbjct: 10059 KVPEVPKKLIPEEKKP--TPVPKKVEAPPPKVPKK 10091



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 50/215 (23%), Positives = 87/215 (40%), Gaps = 16/215 (7%)

Query: 527  PKEVQEMRNKIREQNLQDIKTAGPQSQVLCGV-VMDRS----LVQGELVTASKAIIEKEY 581
            P +V E R ++ ++    I+    + Q +  V +M+       ++ E V+  +    +EY
Sbjct: 9689 PAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEY 9748

Query: 582  QPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHP 641
            + +         P T   D+  E   RE ER ++  E   +  +    K  P++P VP  
Sbjct: 9749 EEYDYKEFEEYEP-TEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEP-VPTK 9806

Query: 642  PPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEP----SEALGFPMLEKEEEAHR 697
            P + P K+ +  VPE             P  P   P+EP     E +   + ++E+E   
Sbjct: 9807 PKAPPAKVLKKAVPEEKVPVPIPKKLKPP--PPKVPEEPKKVFEEKIRISITKREKEQVT 9864

Query: 698  PPSPTEAPTEASPEPAPD--PAPVAEEAAPSAVEE 730
             P+  + P +     A +  P P  E A P  V E
Sbjct: 9865 EPA-AKVPMKPKRVVAEEKVPVPRKEVAPPVRVPE 9898



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 40/149 (26%), Positives = 56/149 (37%), Gaps = 22/149 (14%)

Query: 603   LEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDD 662
             +EEY  E E +    EE      E     P   P VP  P    +  E+  VP P   + 
Sbjct: 9918  VEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKP----VPEEKKPVPVPKKKEA 9973

Query: 663   SDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEE 722
               A      +P++ P +P E +  P+L  ++E   P    E P +          PV EE
Sbjct: 9974  PPAK-----VPEV-PKKPEEKV--PVLIPKKEKPPPAKVPEVPKK----------PVPEE 10015

Query: 723   AAPSAVEEGAAADPGSDGSPGKSPSKKKK 751
               P  V +   A P       K P  +KK
Sbjct: 10016 KVPVPVPKKVEAPPAKVPEVPKKPVPEKK 10044



 Score = 34.7 bits (78), Expect = 0.34
 Identities = 38/143 (26%), Positives = 54/143 (37%), Gaps = 17/143 (11%)

Query: 626   EQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALG 685
             E+K   P  + A P   P  P K+EE  +  P   +          LP    +EP E   
Sbjct: 10196 EKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEE---------VLPVEVTEEPEEE-- 10244

Query: 686   FPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGS---P 742
                + +EE    PPS  E   E +P   P+    A   AP+ V +   A P         
Sbjct: 10245 --PISEEEIPEEPPSIEEVE-EVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPE 10301

Query: 743   GKSPSKKKKKFRTPSFLKKSKKK 765
              K P   +KK   P+ + +  KK
Sbjct: 10302 EKVPVPVQKKEAPPAKVPEVPKK 10324



 Score = 33.9 bits (76), Expect = 0.58
 Identities = 33/140 (23%), Positives = 52/140 (37%), Gaps = 20/140 (14%)

Query: 609  EVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPS-----TPIKLEEDLVPEPTTGDDS 663
            EV +K    E+      +++  +PP  P VP  P        P+  +++  P        
Sbjct: 9318 EVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQK 9377

Query: 664  DAATFK-------------PTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASP 710
               T +             P +P++   +  E    P+  KEEE   PP     P +  P
Sbjct: 9378 GVVTEEKITIVTQREESPPPAVPEIPKKKVPEERK-PVPRKEEEVPPPPKVPALPKKPVP 9436

Query: 711  EP-APDPAPVAEEAAPSAVE 729
            E     P PVA++A P   E
Sbjct: 9437 EEKVAVPVPVAKKAPPPRAE 9456



 Score = 32.3 bits (72), Expect = 1.7
 Identities = 39/144 (27%), Positives = 52/144 (36%), Gaps = 19/144 (13%)

Query: 618   EENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSP 677
             E+ + EA   K +SPP  P V   P    + LEE   P     +   AA  + T+P   P
Sbjct: 10647 EKKVPEAIPPKPESPP--PEVFEEPEE--VALEEP--PAEVVEEPEPAAPPQVTVPPKKP 10700

Query: 678   DEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPE----------PAPDPAPVAEEAAPSA 727
                 +A   P +  ++    P    E P E  PE          P   PA V E      
Sbjct: 10701 VPEKKA---PAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVV 10757

Query: 728   VEEGAAADPGSDGSPGKSPSKKKK 751
              E+  A     +  P K P   KK
Sbjct: 10758 PEKKVAVPKKPEVPPAKVPEVPKK 10781



 Score = 30.0 bits (66), Expect = 8.4
 Identities = 48/212 (22%), Positives = 76/212 (35%), Gaps = 37/212 (17%)

Query: 568  ELVTASKAIIEKEYQ---PHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEA 624
            E++   K + E+ ++   P  +     P P   +        ++ V  K + +   ++E 
Sbjct: 9148 EVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVI--------KKPVIEKIEKTSRRMEEE 9199

Query: 625  REQKEKSPP-DQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEA 683
            + Q  K P   +  VP  P  TP++ E   V  P         + +  +   S  E   +
Sbjct: 9200 KVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVIS-EEKMFFASHTEEEVS 9258

Query: 684  LGFPMLEKE----EEAH--------RPPSPTE-----APTEASPEPAPD----PAPVAEE 722
            +  P ++KE    E+ H         PP   E     AP E +P P P     PAP   E
Sbjct: 9259 VTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPE 9318

Query: 723  AAPSAVEEGAAADP---GSDGSPGKSPSKKKK 751
                 V E     P       +P K P   KK
Sbjct: 9319 VPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKK 9350


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 49/184 (26%), Positives = 73/184 (39%), Gaps = 17/184 (9%)

Query: 589 TTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQ------PAVPHPP 642
           TT  N  T+   +E     +E +  +K S ++L    +   K  P        PA+  P 
Sbjct: 155 TTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK 214

Query: 643 PSTPIKLEEDLVPEPTTGDDSDAATFK--PTLPDLSPDEPSEALGFPMLEKEEE--AHRP 698
             TP   +E   P  TT  +    T K  PT P      P+     P   KE      + 
Sbjct: 215 EPTPTTPKE---PASTTPKEPTPTTIKSAPTTP--KEPAPTTTKSAPTTPKEPAPTTTKE 269

Query: 699 PSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDG-SPGKSPSKKKKKFRTPS 757
           P+PT  P E +P    +PAP   ++AP+  +E A   P     +  K P+    K  TP+
Sbjct: 270 PAPT-TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 328

Query: 758 FLKK 761
             K+
Sbjct: 329 TPKE 332



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 43/148 (29%), Positives = 59/148 (39%), Gaps = 22/148 (14%)

Query: 630 KSPPDQPAVP------HPPPSTPIKLEEDLVPEPTTGDDSDAATFK---PTLPDLSPDEP 680
           KS P  P  P       P P+TP +      P PTT  +    T K   PT  + +P  P
Sbjct: 292 KSAPTTPKEPAPTTPKKPAPTTPKE------PAPTTPKEPTPTTPKEPAPTTKEPAPTTP 345

Query: 681 SEALGFPMLEKEEEAHRPPSPTE----APT---EASPEPAPDPAPVAEEAAPSAVEEGAA 733
            E       +      + P+PT     APT   E SP    +PAP   ++AP+  +E A 
Sbjct: 346 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 405

Query: 734 ADPGSDGSPGKSPSKKKKKFRTPSFLKK 761
               S  +  K PS    K   P+  K+
Sbjct: 406 TTTKSAPTTPKEPSPTTTKEPAPTTPKE 433



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 42/145 (28%), Positives = 56/145 (38%), Gaps = 16/145 (11%)

Query: 622 DEAREQKEKSP--PDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDE 679
           + A   KE +P  P +PA   P    P   +E   P PTT  +    T K   P  +P E
Sbjct: 332 EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE---PAPTTPKEPAPTTTKEPSPT-TPKE 387

Query: 680 PSEAL--GFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA-EEAAPSAVEEGAAADP 736
           P+       P   KE       S    P E SP    +PAP   +E AP+  ++ A   P
Sbjct: 388 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 447

Query: 737 GSDGSPGKSPSKKKKKFRTPSFLKK 761
                  K P+    K   P+  KK
Sbjct: 448 -------KEPAPTTPKEPAPTTTKK 465



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 36/131 (27%), Positives = 54/131 (41%), Gaps = 19/131 (14%)

Query: 628 KEKSP--PDQPA--VPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEA 683
           KE +P  P +PA     P P+TP +      P PT        T K   P  +P EP+  
Sbjct: 323 KEPTPTTPKEPAPTTKEPAPTTPKE------PAPTAPKKPAPTTPKEPAPT-TPKEPA-- 373

Query: 684 LGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGA---AADPGSDG 740
              P   KE     P  P    T+++P    +PAP   ++AP+  +E +     +P    
Sbjct: 374 ---PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 430

Query: 741 SPGKSPSKKKK 751
               +P+  KK
Sbjct: 431 PKEPAPTTPKK 441



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 40/142 (28%), Positives = 58/142 (40%), Gaps = 22/142 (15%)

Query: 628 KEKSP--PDQPA---VPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKP--TLPDLSPDEP 680
           KE +P  P +PA      P P+TP +      P PTT   +   T +P  T    +P  P
Sbjct: 362 KEPAPTTPKEPAPTTTKEPSPTTPKE------PAPTTTKSAPTTTKEPAPTTTKSAPTTP 415

Query: 681 SEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA-EEAAPSAVEEGAAADPGSD 739
            E       E      + P+PT  P + +P    +PAP   +E AP+  ++ A   P   
Sbjct: 416 KEPSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP--- 471

Query: 740 GSPGKSPSKKKKKFRTPSFLKK 761
               K P+    K   P+  KK
Sbjct: 472 ----KEPAPTTPKETAPTTPKK 489



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 37/131 (28%), Positives = 56/131 (42%), Gaps = 17/131 (12%)

Query: 626 EQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALG 685
           E+   + P++PA   P    P   EE   P PTT ++    T K   P+ +P EP+    
Sbjct: 496 EKLAPTTPEKPAPTTPEELAPTTPEE---PTPTTPEEPAPTTPKAAAPN-TPKEPA---- 547

Query: 686 FPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEA-APSAVEEGAAADPGSDGSPGK 744
            P   KE      P+PT  P E +P    + AP   +  AP+ ++E A   P        
Sbjct: 548 -PTTPKE------PAPT-TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 599

Query: 745 SPSKKKKKFRT 755
           +P+  K+   T
Sbjct: 600 APTTTKEPTST 610



 Score = 38.5 bits (88), Expect = 0.024
 Identities = 44/141 (31%), Positives = 62/141 (43%), Gaps = 26/141 (18%)

Query: 628 KEKSP--PDQPA---VPHPPPSTPIKLEEDLVPEPTTGDDSDAATFK---PTLPD-LSPD 678
           KE +P  P +PA      P P+TP +      P PTT  ++   T K   PT P+ L+P 
Sbjct: 448 KEPAPTTPKEPAPTTTKKPAPTTPKE------PAPTTPKETAPTTPKKLTPTTPEKLAPT 501

Query: 679 EPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA-EEAAPSAVEEGAAADPG 737
            P +    P     EE    P+  E PT  +PE   +PAP   + AAP+  +E A   P 
Sbjct: 502 TPEK----PAPTTPEEL--APTTPEEPTPTTPE---EPAPTTPKAAAPNTPKEPAPTTPK 552

Query: 738 SDG-SPGKSPSKKKKKFRTPS 757
               +  K P+    K   P+
Sbjct: 553 EPAPTTPKEPAPTTPKETAPT 573



 Score = 36.6 bits (83), Expect = 0.090
 Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 24/131 (18%)

Query: 634 DQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEE 693
           D+PA   P  + P   +E   P PTT          PT P+  P   SE +  P   KE 
Sbjct: 682 DKPAPTTPKETAPTTPKE---PAPTTPKKP-----APTTPETPPPTTSE-VSTPTTTKE- 731

Query: 694 EAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKF 753
               P +  ++P E++PE + +P P A E +P         +PG   +  K+P+  K + 
Sbjct: 732 ----PTTIHKSPDESTPELSAEPTPKALENSPK--------EPGVPTT--KTPAATKPEM 777

Query: 754 RTPSFLKKSKK 764
            T +  K +++
Sbjct: 778 TTTAKDKTTER 788



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 37/179 (20%), Positives = 69/179 (38%), Gaps = 22/179 (12%)

Query: 588 STTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPI 647
           S T      T+      E +      ++ S +  ++    KE    ++ +     P++ +
Sbjct: 134 SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV 193

Query: 648 KLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTE 707
                 + +PT    ++  T  P L   +P EP+     P   KE  +  P  PT    +
Sbjct: 194 ------LAKPTP--KAETTTKGPALT--TPKEPT-----PTTPKEPASTTPKEPTPTTIK 238

Query: 708 ASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPG----KSPSKKKKKFRTPSFLKKS 762
           ++P    +PAP   ++AP+  +E A   P +   P     K P+    K   P+  K +
Sbjct: 239 SAPTTPKEPAPTTTKSAPTTPKEPA---PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 294



 Score = 33.9 bits (76), Expect = 0.58
 Identities = 33/119 (27%), Positives = 43/119 (36%), Gaps = 15/119 (12%)

Query: 633 PDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKE 692
           P  P  P P    P   +E   P  TT D     T K T P  +P EP+          +
Sbjct: 588 PTTPKKPAPKELAPTTTKE---PTSTTCDKPAPTTPKGTAPT-TPKEPAPTT------PK 637

Query: 693 EEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKK 751
           E A   P  T   T   P P     P  +E AP+  +      P S  S   +P+  K+
Sbjct: 638 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK-----GPTSTTSDKPAPTTPKE 691



 Score = 33.1 bits (74), Expect = 1.00
 Identities = 31/90 (34%), Positives = 36/90 (40%), Gaps = 9/90 (10%)

Query: 628 KEKSP--PDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFK-PTLPDLSPDEPSEAL 684
           KE +P  P +PA   P    P   E    P PTT + S   T K PT    SPDE +  L
Sbjct: 690 KETAPTTPKEPAPTTPKKPAPTTPE---TPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 746

Query: 685 GFPMLEK--EEEAHRPPSP-TEAPTEASPE 711
                 K  E     P  P T+ P    PE
Sbjct: 747 SAEPTPKALENSPKEPGVPTTKTPAATKPE 776


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.130    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,035,117
Number of Sequences: 37866
Number of extensions: 1953187
Number of successful extensions: 19171
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 203
Number of HSP's successfully gapped in prelim test: 1028
Number of HSP's that attempted gapping in prelim test: 12415
Number of HSP's gapped (non-prelim): 5520
length of query: 768
length of database: 18,247,518
effective HSP length: 110
effective length of query: 658
effective length of database: 14,082,258
effective search space: 9266125764
effective search space used: 9266125764
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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