Guide to the Human Genome
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Search of human proteins with 12232469

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|12232469 required for meiotic nuclear division 5 homolog A
[Homo sapiens]
         (391 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|12232469 required for meiotic nuclear division 5 homolog A [H...   794   0.0  
gi|21362098 required for meiotic nuclear division 5 homolog B [H...   570   e-162
gi|62953131 macrophage erythroblast attacher isoform 1 [Homo sap...    75   1e-13
gi|62953129 macrophage erythroblast attacher isoform 2 [Homo sap...    47   4e-05
gi|153791514 tripartite motif-containing 32 [Homo sapiens]             34   0.20 
gi|153792582 tripartite motif-containing 32 [Homo sapiens]             34   0.20 
gi|6912734 transportin 3 [Homo sapiens]                                33   0.34 
gi|27734761 non-SMC element 2, MMS21 homolog [Homo sapiens]            32   0.98 
gi|37595555 ring finger protein 125 [Homo sapiens]                     31   1.7  
gi|9558729 golgi associated, gamma adaptin ear containing, ARF b...    31   1.7  
gi|115430235 ubiquitin-like with PHD and ring finger domains 1 i...    31   2.2  
gi|115430233 ubiquitin-like with PHD and ring finger domains 1 i...    31   2.2  
gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]    31   2.2  
gi|30794216 tripartite motif-containing 56 [Homo sapiens]              30   3.7  
gi|118498362 kinectin 1 isoform b [Homo sapiens]                       30   4.9  
gi|118498356 kinectin 1 isoform a [Homo sapiens]                       30   4.9  
gi|118498368 kinectin 1 isoform c [Homo sapiens]                       30   4.9  
gi|33620775 kinectin 1 isoform a [Homo sapiens]                        30   4.9  
gi|15208643 ADP-ribosylation factor domain protein 1 isoform gam...    30   4.9  
gi|15208641 ADP-ribosylation factor domain protein 1 isoform bet...    30   4.9  
gi|4502197 ADP-ribosylation factor domain protein 1 isoform alph...    30   4.9  
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]                    29   6.4  
gi|151101270 troponin I, cardiac [Homo sapiens]                        29   8.3  
gi|197333692 leucine rich repeat containing 8 family, member B [...    29   8.3  
gi|21245134 leucine rich repeat containing 8 family, member B [H...    29   8.3  
gi|156105697 ring finger and CCCH-type zinc finger domains 2 iso...    29   8.3  
gi|73695473 roquin [Homo sapiens]                                      29   8.3  
gi|156105699 ring finger and CCCH-type zinc finger domains 2 iso...    29   8.3  
gi|48527952 golgi associated, gamma adaptin ear containing, ARF ...    29   8.3  

>gi|12232469 required for meiotic nuclear division 5 homolog A [Homo
           sapiens]
          Length = 391

 Score =  794 bits (2050), Expect = 0.0
 Identities = 391/391 (100%), Positives = 391/391 (100%)

Query: 1   MDQCVTVERELEKVLHKFSGYGQLCERGLEELIDYTGGLKHEILQSHGQDAELSGTLSLV 60
           MDQCVTVERELEKVLHKFSGYGQLCERGLEELIDYTGGLKHEILQSHGQDAELSGTLSLV
Sbjct: 1   MDQCVTVERELEKVLHKFSGYGQLCERGLEELIDYTGGLKHEILQSHGQDAELSGTLSLV 60

Query: 61  LTQCCKRIKDTVQKLASDHKDIHSSVSRVGKAIDKNFDSDISSVGIDGCWQADSQRLLNE 120
           LTQCCKRIKDTVQKLASDHKDIHSSVSRVGKAIDKNFDSDISSVGIDGCWQADSQRLLNE
Sbjct: 61  LTQCCKRIKDTVQKLASDHKDIHSSVSRVGKAIDKNFDSDISSVGIDGCWQADSQRLLNE 120

Query: 121 VMVEHFFRQGMLDVAEELCQESGLSVDPSQKEPFVELNRILEALKVRVLRPALEWAVSNR 180
           VMVEHFFRQGMLDVAEELCQESGLSVDPSQKEPFVELNRILEALKVRVLRPALEWAVSNR
Sbjct: 121 VMVEHFFRQGMLDVAEELCQESGLSVDPSQKEPFVELNRILEALKVRVLRPALEWAVSNR 180

Query: 181 EMLIAQNSSLEFKLHRLYFISLLMGGTTNQREALQYAKNFQPFALNHQKDIQVLMGSLVY 240
           EMLIAQNSSLEFKLHRLYFISLLMGGTTNQREALQYAKNFQPFALNHQKDIQVLMGSLVY
Sbjct: 181 EMLIAQNSSLEFKLHRLYFISLLMGGTTNQREALQYAKNFQPFALNHQKDIQVLMGSLVY 240

Query: 241 LRQGIENSPYVHLLDANQWADICDIFTRDACALLGLSVESPLSVSFSAGCVALPALINIK 300
           LRQGIENSPYVHLLDANQWADICDIFTRDACALLGLSVESPLSVSFSAGCVALPALINIK
Sbjct: 241 LRQGIENSPYVHLLDANQWADICDIFTRDACALLGLSVESPLSVSFSAGCVALPALINIK 300

Query: 301 AVIEQRQCTGVWNQKDELPIEVDLGKKCWYHSIFACPILRQQTTDNNPPMKLVCGHIISR 360
           AVIEQRQCTGVWNQKDELPIEVDLGKKCWYHSIFACPILRQQTTDNNPPMKLVCGHIISR
Sbjct: 301 AVIEQRQCTGVWNQKDELPIEVDLGKKCWYHSIFACPILRQQTTDNNPPMKLVCGHIISR 360

Query: 361 DALNKMFNGSKLKCPYCPMEQSPGDAKQIFF 391
           DALNKMFNGSKLKCPYCPMEQSPGDAKQIFF
Sbjct: 361 DALNKMFNGSKLKCPYCPMEQSPGDAKQIFF 391


>gi|21362098 required for meiotic nuclear division 5 homolog B [Homo
           sapiens]
          Length = 393

 Score =  570 bits (1468), Expect = e-162
 Identities = 275/393 (69%), Positives = 325/393 (82%), Gaps = 2/393 (0%)

Query: 1   MDQCVTVERELEKVLHKFSGYGQLCERGLEELIDYTGGLKHEILQSHGQDAELSGTLSLV 60
           M+QC  VEREL+KVL KF  YGQ CER LEEL+ Y G L+ E+  +  Q   LS TLSLV
Sbjct: 1   MEQCACVERELDKVLQKFLTYGQHCERSLEELLHYVGQLRAELASAALQGTPLSATLSLV 60

Query: 61  LTQCCKRIKDTVQKLASDHKDIHSSVSRVGKAIDKNFDSDISSVGIDGCWQA--DSQRLL 118
           ++QCC++IKDTVQKLASDHKDIHSSVSRVGKAID+NFDS+I  V  D  W A    Q++L
Sbjct: 61  MSQCCRKIKDTVQKLASDHKDIHSSVSRVGKAIDRNFDSEICGVVSDAVWDAREQQQQIL 120

Query: 119 NEVMVEHFFRQGMLDVAEELCQESGLSVDPSQKEPFVELNRILEALKVRVLRPALEWAVS 178
              +VEH ++QGML VAEELCQES L+VD   K+PF+ELNRILEAL  + L PALEWAVS
Sbjct: 121 QMAIVEHLYQQGMLSVAEELCQESTLNVDLDFKQPFLELNRILEALHEQDLGPALEWAVS 180

Query: 179 NREMLIAQNSSLEFKLHRLYFISLLMGGTTNQREALQYAKNFQPFALNHQKDIQVLMGSL 238
           +R+ L+  NSSLEFKLHRL+FI LL GG   Q EAL YA++FQPFA  HQ++IQV+MGSL
Sbjct: 181 HRQRLLELNSSLEFKLHRLHFIRLLAGGPAKQLEALSYARHFQPFARLHQREIQVMMGSL 240

Query: 239 VYLRQGIENSPYVHLLDANQWADICDIFTRDACALLGLSVESPLSVSFSAGCVALPALIN 298
           VYLR G+E SPY HLLD++ WA+IC+ FTRDAC+LLGLSVESPLSVSF++GCVALP L+N
Sbjct: 241 VYLRLGLEKSPYCHLLDSSHWAEICETFTRDACSLLGLSVESPLSVSFASGCVALPVLMN 300

Query: 299 IKAVIEQRQCTGVWNQKDELPIEVDLGKKCWYHSIFACPILRQQTTDNNPPMKLVCGHII 358
           IKAVIEQRQCTGVWN KDELPIE++LG KCWYHS+FACPILRQQT+D+NPP+KL+CGH+I
Sbjct: 301 IKAVIEQRQCTGVWNHKDELPIEIELGMKCWYHSVFACPILRQQTSDSNPPIKLICGHVI 360

Query: 359 SRDALNKMFNGSKLKCPYCPMEQSPGDAKQIFF 391
           SRDALNK+ NG KLKCPYCPMEQ+P D K+I F
Sbjct: 361 SRDALNKLINGGKLKCPYCPMEQNPADGKRIIF 393


>gi|62953131 macrophage erythroblast attacher isoform 1 [Homo
           sapiens]
          Length = 396

 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 69/265 (26%), Positives = 115/265 (43%), Gaps = 11/265 (4%)

Query: 115 QRLLNEVMVEHFFRQGMLDVAEELCQESGLSVDPSQKEPFVELNRILEALKVRVLRPALE 174
           ++ ++ +MVEH  R G  + A +L ++SG+  D    E F+    + E+L+ R     L 
Sbjct: 122 RKRMDRMMVEHLLRCGYYNTAVKLARQSGIE-DLVNIEMFLTAKEVEESLERRETATCLA 180

Query: 175 WAVSNREMLIAQNSSLEFKLHRLYFISLLMGGTTNQR-EALQYA-KNFQPFALNHQKDIQ 232
           W   N+  L    S LEF L    FI L+     N+R +A+++A K+F     +   +++
Sbjct: 181 WCHDNKSRLRKMKSCLEFSLRIQEFIELIR---QNKRLDAVRHARKHFSQAEGSQLDEVR 237

Query: 233 VLMGSLVYLRQGIENSPYVHLLDANQWADICDIFTRDACALLGLSVESPLSVSFSAGCVA 292
             MG L +       SPY  LLD  +W  +   F  D   L  L   S  +++  AG  A
Sbjct: 238 QAMGMLAF-PPDTHISPYKDLLDPARWRMLIQQFRYDNYRLHQLGNNSVFTLTLQAGLSA 296

Query: 293 L--PALINIKAVIEQRQCTGVWNQKDELPIEVDLGKKCWYHSIFACPILRQQTTDNNPPM 350
           +  P         +   C       ++L   + +      +S   C I      +NNPPM
Sbjct: 297 IKTPQCYKEDGSSKSPDCPVCSRSLNKLAQPLPMAHCA--NSRLVCKISGDVMNENNPPM 354

Query: 351 KLVCGHIISRDALNKMFNGSKLKCP 375
            L  G++   ++L  +    K+ CP
Sbjct: 355 MLPNGYVYGYNSLLSIRQDDKVVCP 379


>gi|62953129 macrophage erythroblast attacher isoform 2 [Homo
           sapiens]
          Length = 355

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 59/265 (22%), Positives = 100/265 (37%), Gaps = 52/265 (19%)

Query: 115 QRLLNEVMVEHFFRQGMLDVAEELCQESGLSVDPSQKEPFVELNRILEALKVRVLRPALE 174
           ++ ++ +MVEH  R G  + A +L ++SG+                              
Sbjct: 122 RKRMDRMMVEHLLRCGYYNTAVKLARQSGIE----------------------------- 152

Query: 175 WAVSNREMLIAQNSSLEFKLHRLYFISLLMGGTTNQR-EALQYA-KNFQPFALNHQKDIQ 232
                        S LEF L    FI L+     N+R +A+++A K+F     +   +++
Sbjct: 153 -------------SCLEFSLRIQEFIELIR---QNKRLDAVRHARKHFSQAEGSQLDEVR 196

Query: 233 VLMGSLVYLRQGIENSPYVHLLDANQWADICDIFTRDACALLGLSVESPLSVSFSAGCVA 292
             MG L +       SPY  LLD  +W  +   F  D   L  L   S  +++  AG  A
Sbjct: 197 QAMGMLAF-PPDTHISPYKDLLDPARWRMLIQQFRYDNYRLHQLGNNSVFTLTLQAGLSA 255

Query: 293 L--PALINIKAVIEQRQCTGVWNQKDELPIEVDLGKKCWYHSIFACPILRQQTTDNNPPM 350
           +  P         +   C       ++L   + +      +S   C I      +NNPPM
Sbjct: 256 IKTPQCYKEDGSSKSPDCPVCSRSLNKLAQPLPMAHCA--NSRLVCKISGDVMNENNPPM 313

Query: 351 KLVCGHIISRDALNKMFNGSKLKCP 375
            L  G++   ++L  +    K+ CP
Sbjct: 314 MLPNGYVYGYNSLLSIRQDDKVVCP 338


>gi|153791514 tripartite motif-containing 32 [Homo sapiens]
          Length = 653

 Score = 34.3 bits (77), Expect = 0.20
 Identities = 17/48 (35%), Positives = 25/48 (52%), Gaps = 3/48 (6%)

Query: 333 IFACPILRQQTTDNNPPMKLV-CGHIISRDALNKMFNGS--KLKCPYC 377
           +  CPI  +  T+     KL+ CGH I R  L K+   S   ++CP+C
Sbjct: 17  VLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFC 64


>gi|153792582 tripartite motif-containing 32 [Homo sapiens]
          Length = 653

 Score = 34.3 bits (77), Expect = 0.20
 Identities = 17/48 (35%), Positives = 25/48 (52%), Gaps = 3/48 (6%)

Query: 333 IFACPILRQQTTDNNPPMKLV-CGHIISRDALNKMFNGS--KLKCPYC 377
           +  CPI  +  T+     KL+ CGH I R  L K+   S   ++CP+C
Sbjct: 17  VLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFC 64


>gi|6912734 transportin 3 [Homo sapiens]
          Length = 923

 Score = 33.5 bits (75), Expect = 0.34
 Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 14/77 (18%)

Query: 117 LLNEVMVEHFFRQGMLDVAEELC--------QESGLSVDPSQKEPFVEL-NRILEALKVR 167
           L++E  +E   RQG+LD+ + LC        Q++GL   P   +    L  R ++   V 
Sbjct: 707 LVDEYGMEEGCRQGLLDMLQALCIPTFQLLEQQNGLQNHPDTVDDLFRLATRFIQRSPVT 766

Query: 168 VLR-----PALEWAVSN 179
           +LR     P L+WA+++
Sbjct: 767 LLRSQVVIPILQWAIAS 783


>gi|27734761 non-SMC element 2, MMS21 homolog [Homo sapiens]
          Length = 247

 Score = 32.0 bits (71), Expect = 0.98
 Identities = 16/47 (34%), Positives = 22/47 (46%), Gaps = 4/47 (8%)

Query: 334 FACPILRQQTTDNNPPMKLVCGHIISRDALNKMFNG--SKLKCPYCP 378
           F CPI +++     P    VCGH    DA+ +M      + K  YCP
Sbjct: 167 FTCPITKEEM--KKPVKNKVCGHTYEEDAIVRMIESRQKRKKKAYCP 211


>gi|37595555 ring finger protein 125 [Homo sapiens]
          Length = 232

 Score = 31.2 bits (69), Expect = 1.7
 Identities = 10/29 (34%), Positives = 15/29 (51%)

Query: 349 PMKLVCGHIISRDALNKMFNGSKLKCPYC 377
           P++  CGH+  R  +      +K  CPYC
Sbjct: 47  PVRTRCGHVFCRSCIATSLKNNKWTCPYC 75


>gi|9558729 golgi associated, gamma adaptin ear containing, ARF
           binding protein 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 31.2 bits (69), Expect = 1.7
 Identities = 18/56 (32%), Positives = 33/56 (58%), Gaps = 3/56 (5%)

Query: 42  EILQSHGQDAELSGT---LSLVLTQCCKRIKDTVQKLASDHKDIHSSVSRVGKAID 94
           E++ SH Q    +G+   L   L Q C+R++ T+ +LASD +D   +++ + +A D
Sbjct: 230 EMVMSHSQGGAAAGSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQAND 285


>gi|115430235 ubiquitin-like with PHD and ring finger domains 1
           isoform 1 [Homo sapiens]
          Length = 793

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 12/41 (29%), Positives = 19/41 (46%)

Query: 349 PMKLVCGHIISRDALNKMFNGSKLKCPYCPMEQSPGDAKQI 389
           P+  VC H + +D L++ F      CP C  +     A Q+
Sbjct: 734 PITTVCQHNVCKDCLDRSFRAQVFSCPACRYDLGRSYAMQV 774


>gi|115430233 ubiquitin-like with PHD and ring finger domains 1
           isoform 2 [Homo sapiens]
          Length = 806

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 12/41 (29%), Positives = 19/41 (46%)

Query: 349 PMKLVCGHIISRDALNKMFNGSKLKCPYCPMEQSPGDAKQI 389
           P+  VC H + +D L++ F      CP C  +     A Q+
Sbjct: 747 PITTVCQHNVCKDCLDRSFRAQVFSCPACRYDLGRSYAMQV 787


>gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]
          Length = 1498

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 46/196 (23%), Positives = 83/196 (42%), Gaps = 21/196 (10%)

Query: 19  SGYGQLCERGLEELIDYTGGLKHEILQSHGQDAELSGTLSLVLTQCCKRIKDTVQKLASD 78
           S Y     RG   ++  T G +      +GQ+   + TL    +     IKD +Q  A++
Sbjct: 318 SSYSSASTRGTYGILSKTVGTQDTPYMVNGQEIP-ADTLGQFPS-----IKDVLQAAAAE 371

Query: 79  HKDIHSSVSRVGKAIDKNFDSDISSVGIDGCWQADSQRLLNEVMVEHFFRQGMLDVAEEL 138
           H+D       V   +    DS  SSV ++    A++Q  + +V+ E    +G L+     
Sbjct: 372 HQD---QGQEVNGEVRSRRDSICSSVSLESS-AAETQEEMLQVLKEKMRLEGQLE----- 422

Query: 139 CQESGLSVDPSQK-EPFVELNRILEALKVRVLRPALEWAVSNREMLIAQNSSLEFKLHRL 197
                LS++ SQ  +   EL   L AL  + L+  +E + S+++   + +S ++      
Sbjct: 423 ----ALSLEASQALKEKAELQAQLAALSTK-LQAQVECSHSSQQRQDSLSSEVDTLKQSC 477

Query: 198 YFISLLMGGTTNQREA 213
           + +   M    N  EA
Sbjct: 478 WDLERAMTDLQNMLEA 493


>gi|30794216 tripartite motif-containing 56 [Homo sapiens]
          Length = 755

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 14/43 (32%), Positives = 22/43 (51%), Gaps = 3/43 (6%)

Query: 335 ACPILRQQTTDNNPPMKLVCGHIISRDALNKMFNGSKLKCPYC 377
           AC I  +Q      P  L C H   +D L ++ +G +++CP C
Sbjct: 20  ACKICLEQL---RAPKTLPCLHTYCQDCLAQLADGGRVRCPEC 59


>gi|118498362 kinectin 1 isoform b [Homo sapiens]
          Length = 1306

 Score = 29.6 bits (65), Expect = 4.9
 Identities = 41/187 (21%), Positives = 81/187 (43%), Gaps = 17/187 (9%)

Query: 29  LEELIDYTGGLKHEILQSHGQDAE------LSGTLSLVLTQCCKRIKDTVQKLASDHKDI 82
           ++++++    LK +I Q H Q A       L+  L  V+ +  K+IK T   LAS+   +
Sbjct: 571 VQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRL 630

Query: 83  HSSVSRVGKAIDKNF--DSDISSVGIDGCWQADSQRLLNEVMVEHFFRQGMLDVAEELCQ 140
            S    +    + NF   +++  +      QA +   L ++    + +   + + EE  Q
Sbjct: 631 TSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQ 690

Query: 141 ESGLSVDPSQKEPFVELNRILEALKVRVLRPALEWAVS---NREMLIAQNSSLEFKLHRL 197
                   ++ E F  LN   +ALK  V +  L+  VS   N++++      ++ K  +L
Sbjct: 691 HE----ISNKMEEFKILNDQNKALKSEVQK--LQTLVSEQPNKDVVEQMEKCIQEKDEKL 744

Query: 198 YFISLLM 204
             +  L+
Sbjct: 745 KTVEELL 751


>gi|118498356 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 29.6 bits (65), Expect = 4.9
 Identities = 41/187 (21%), Positives = 81/187 (43%), Gaps = 17/187 (9%)

Query: 29  LEELIDYTGGLKHEILQSHGQDAE------LSGTLSLVLTQCCKRIKDTVQKLASDHKDI 82
           ++++++    LK +I Q H Q A       L+  L  V+ +  K+IK T   LAS+   +
Sbjct: 571 VQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRL 630

Query: 83  HSSVSRVGKAIDKNF--DSDISSVGIDGCWQADSQRLLNEVMVEHFFRQGMLDVAEELCQ 140
            S    +    + NF   +++  +      QA +   L ++    + +   + + EE  Q
Sbjct: 631 TSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQ 690

Query: 141 ESGLSVDPSQKEPFVELNRILEALKVRVLRPALEWAVS---NREMLIAQNSSLEFKLHRL 197
                   ++ E F  LN   +ALK  V +  L+  VS   N++++      ++ K  +L
Sbjct: 691 HE----ISNKMEEFKILNDQNKALKSEVQK--LQTLVSEQPNKDVVEQMEKCIQEKDEKL 744

Query: 198 YFISLLM 204
             +  L+
Sbjct: 745 KTVEELL 751


>gi|118498368 kinectin 1 isoform c [Homo sapiens]
          Length = 1300

 Score = 29.6 bits (65), Expect = 4.9
 Identities = 41/187 (21%), Positives = 81/187 (43%), Gaps = 17/187 (9%)

Query: 29  LEELIDYTGGLKHEILQSHGQDAE------LSGTLSLVLTQCCKRIKDTVQKLASDHKDI 82
           ++++++    LK +I Q H Q A       L+  L  V+ +  K+IK T   LAS+   +
Sbjct: 571 VQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRL 630

Query: 83  HSSVSRVGKAIDKNF--DSDISSVGIDGCWQADSQRLLNEVMVEHFFRQGMLDVAEELCQ 140
            S    +    + NF   +++  +      QA +   L ++    + +   + + EE  Q
Sbjct: 631 TSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQ 690

Query: 141 ESGLSVDPSQKEPFVELNRILEALKVRVLRPALEWAVS---NREMLIAQNSSLEFKLHRL 197
                   ++ E F  LN   +ALK  V +  L+  VS   N++++      ++ K  +L
Sbjct: 691 HE----ISNKMEEFKILNDQNKALKSEVQK--LQTLVSEQPNKDVVEQMEKCIQEKDEKL 744

Query: 198 YFISLLM 204
             +  L+
Sbjct: 745 KTVEELL 751


>gi|33620775 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 29.6 bits (65), Expect = 4.9
 Identities = 41/187 (21%), Positives = 81/187 (43%), Gaps = 17/187 (9%)

Query: 29  LEELIDYTGGLKHEILQSHGQDAE------LSGTLSLVLTQCCKRIKDTVQKLASDHKDI 82
           ++++++    LK +I Q H Q A       L+  L  V+ +  K+IK T   LAS+   +
Sbjct: 571 VQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRL 630

Query: 83  HSSVSRVGKAIDKNF--DSDISSVGIDGCWQADSQRLLNEVMVEHFFRQGMLDVAEELCQ 140
            S    +    + NF   +++  +      QA +   L ++    + +   + + EE  Q
Sbjct: 631 TSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQ 690

Query: 141 ESGLSVDPSQKEPFVELNRILEALKVRVLRPALEWAVS---NREMLIAQNSSLEFKLHRL 197
                   ++ E F  LN   +ALK  V +  L+  VS   N++++      ++ K  +L
Sbjct: 691 HE----ISNKMEEFKILNDQNKALKSEVQK--LQTLVSEQPNKDVVEQMEKCIQEKDEKL 744

Query: 198 YFISLLM 204
             +  L+
Sbjct: 745 KTVEELL 751


>gi|15208643 ADP-ribosylation factor domain protein 1 isoform gamma
           [Homo sapiens]
          Length = 546

 Score = 29.6 bits (65), Expect = 4.9
 Identities = 12/39 (30%), Positives = 21/39 (53%), Gaps = 1/39 (2%)

Query: 349 PMKLVCGHIISRDALNKM-FNGSKLKCPYCPMEQSPGDA 386
           P  L+CGH +  D L ++  +G  ++CP+       GD+
Sbjct: 46  PRLLLCGHTVCHDCLTRLPLHGRAIRCPFDRQVTDLGDS 84


>gi|15208641 ADP-ribosylation factor domain protein 1 isoform beta
           [Homo sapiens]
          Length = 569

 Score = 29.6 bits (65), Expect = 4.9
 Identities = 12/39 (30%), Positives = 21/39 (53%), Gaps = 1/39 (2%)

Query: 349 PMKLVCGHIISRDALNKM-FNGSKLKCPYCPMEQSPGDA 386
           P  L+CGH +  D L ++  +G  ++CP+       GD+
Sbjct: 46  PRLLLCGHTVCHDCLTRLPLHGRAIRCPFDRQVTDLGDS 84


>gi|4502197 ADP-ribosylation factor domain protein 1 isoform alpha
           [Homo sapiens]
          Length = 574

 Score = 29.6 bits (65), Expect = 4.9
 Identities = 12/39 (30%), Positives = 21/39 (53%), Gaps = 1/39 (2%)

Query: 349 PMKLVCGHIISRDALNKM-FNGSKLKCPYCPMEQSPGDA 386
           P  L+CGH +  D L ++  +G  ++CP+       GD+
Sbjct: 46  PRLLLCGHTVCHDCLTRLPLHGRAIRCPFDRQVTDLGDS 84


>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
          Length = 284

 Score = 29.3 bits (64), Expect = 6.4
 Identities = 42/166 (25%), Positives = 65/166 (39%), Gaps = 18/166 (10%)

Query: 2   DQCVTVERELEKVLHKFSGYGQLCERGLEELIDYTGGLKHEILQSHGQDAE-----LSGT 56
           D+C  VE EL  +  K  G     ++  E+L D     K E+ +    DAE     L+  
Sbjct: 34  DKCKQVEEELTHLQKKLKGTEDELDKYSEDLKD--AQEKLELTEKKASDAEGDVAALNRR 91

Query: 57  LSLV---LTQCCKRIKDTVQKLASDHKDIHSSVSRVGKAIDKNFDSDISSVGIDGCW--- 110
           + LV   L +  +R+   +QKL    K    S  R  K I+     D   + I       
Sbjct: 92  IQLVEEELDRAQERLATALQKLEEAEKAADES-ERGMKVIENRAMKDEEKMEIQEMQLKE 150

Query: 111 ----QADSQRLLNEVMVEHFFRQGMLDVAEELCQESGLSVDPSQKE 152
                 ++ R   EV  +    +G L+ AEE  + S L     ++E
Sbjct: 151 AKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEE 196


>gi|151101270 troponin I, cardiac [Homo sapiens]
          Length = 210

 Score = 28.9 bits (63), Expect = 8.3
 Identities = 17/66 (25%), Positives = 31/66 (46%)

Query: 23  QLCERGLEELIDYTGGLKHEILQSHGQDAELSGTLSLVLTQCCKRIKDTVQKLASDHKDI 82
           Q+ ++ LE   +   G K   L +  Q  EL+G     L   C+++   V K+  +  DI
Sbjct: 55  QIAKQELEREAEERRGEKGRALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDI 114

Query: 83  HSSVSR 88
            + V++
Sbjct: 115 EAKVTK 120


>gi|197333692 leucine rich repeat containing 8 family, member B
           [Homo sapiens]
          Length = 803

 Score = 28.9 bits (63), Expect = 8.3
 Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 7/74 (9%)

Query: 171 PALEWAVSNREMLIAQNSSLE------FKLHRLYFISLLMGGTTNQREALQYAKNFQPFA 224
           PA   A+SN E L   ++++E      F   +L+++ L     T   E +QY  N Q FA
Sbjct: 649 PAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFA 708

Query: 225 LNHQKDIQVLMGSL 238
           + +  +I++L   L
Sbjct: 709 VTN-NNIEMLPDGL 721


>gi|21245134 leucine rich repeat containing 8 family, member B [Homo
           sapiens]
          Length = 803

 Score = 28.9 bits (63), Expect = 8.3
 Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 7/74 (9%)

Query: 171 PALEWAVSNREMLIAQNSSLE------FKLHRLYFISLLMGGTTNQREALQYAKNFQPFA 224
           PA   A+SN E L   ++++E      F   +L+++ L     T   E +QY  N Q FA
Sbjct: 649 PAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFA 708

Query: 225 LNHQKDIQVLMGSL 238
           + +  +I++L   L
Sbjct: 709 VTN-NNIEMLPDGL 721


>gi|156105697 ring finger and CCCH-type zinc finger domains 2
           isoform 1 [Homo sapiens]
          Length = 1191

 Score = 28.9 bits (63), Expect = 8.3
 Identities = 14/49 (28%), Positives = 25/49 (51%), Gaps = 7/49 (14%)

Query: 335 ACPILRQQTTDN-NPPMKLVCGHIISRDALNKMFNGSKLKCPYCPMEQS 382
           +CPI   +  +N + P+ L C H + +  LNK+   +      CP +Q+
Sbjct: 13  SCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKA------CPFDQT 55


>gi|73695473 roquin [Homo sapiens]
          Length = 1133

 Score = 28.9 bits (63), Expect = 8.3
 Identities = 15/49 (30%), Positives = 24/49 (48%), Gaps = 7/49 (14%)

Query: 335 ACPILRQQTTDN-NPPMKLVCGHIISRDALNKMFNGSKLKCPYCPMEQS 382
           +CPI  Q   +    P+ L CGH + +  LNK+   +      CP +Q+
Sbjct: 13  SCPICTQTFDETIRKPISLGCGHTVCKMCLNKLHRKA------CPFDQT 55


>gi|156105699 ring finger and CCCH-type zinc finger domains 2
           isoform 2 [Homo sapiens]
          Length = 1064

 Score = 28.9 bits (63), Expect = 8.3
 Identities = 14/49 (28%), Positives = 25/49 (51%), Gaps = 7/49 (14%)

Query: 335 ACPILRQQTTDN-NPPMKLVCGHIISRDALNKMFNGSKLKCPYCPMEQS 382
           +CPI   +  +N + P+ L C H + +  LNK+   +      CP +Q+
Sbjct: 13  SCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKA------CPFDQT 55


>gi|48527952 golgi associated, gamma adaptin ear containing, ARF
           binding protein 1 isoform 2 [Homo sapiens]
          Length = 552

 Score = 28.9 bits (63), Expect = 8.3
 Identities = 16/43 (37%), Positives = 26/43 (60%), Gaps = 3/43 (6%)

Query: 42  EILQSHGQDAELSGT---LSLVLTQCCKRIKDTVQKLASDHKD 81
           E++ SH Q    +G+   L   L Q C+R++ T+ +LASD +D
Sbjct: 230 EMVMSHSQGGAAAGSSEDLMKELYQRCERMRPTLFRLASDTED 272


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,424,173
Number of Sequences: 37866
Number of extensions: 601731
Number of successful extensions: 1382
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 1364
Number of HSP's gapped (non-prelim): 34
length of query: 391
length of database: 18,247,518
effective HSP length: 104
effective length of query: 287
effective length of database: 14,309,454
effective search space: 4106813298
effective search space used: 4106813298
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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