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Search of human proteins with 29337286
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|29337286 eukaryotic translation initiation factor 2C, 3
isoform b [Homo sapiens]
(626 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|29337286 eukaryotic translation initiation factor 2C, 3 isofo... 1283 0.0
gi|29294647 eukaryotic translation initiation factor 2C, 3 isofo... 1283 0.0
gi|6912352 eukaryotic translation initiation factor 2C, 1 [Homo ... 1174 0.0
gi|29029593 eukaryotic translation initiation factor 2C, 4 [Homo... 1125 0.0
gi|29171734 eukaryotic translation initiation factor 2C, 2 [Homo... 1119 0.0
gi|66346725 piwi-like 1 [Homo sapiens] 151 2e-36
gi|221316711 piwi-like 4 [Homo sapiens] 145 1e-34
gi|209180418 piwi-like 2 [Homo sapiens] 142 1e-33
gi|24431985 piwi-like 2 [Homo sapiens] 142 1e-33
gi|153792298 piwi-like 3 [Homo sapiens] 129 8e-30
gi|169217928 PREDICTED: similar to piwi like homolog 2 [Homo sap... 50 8e-06
gi|126507091 LATS, large tumor suppressor, homolog 2 [Homo sapiens] 34 0.46
gi|114199473 vacuolar protein sorting 41 isoform 2 [Homo sapiens] 34 0.46
gi|114199475 vacuolar protein sorting 41 isoform 1 [Homo sapiens] 34 0.46
gi|4502743 cyclin-dependent kinase 7 [Homo sapiens] 31 3.9
gi|39812019 amino-terminal enhancer of split isoform a [Homo sap... 30 6.7
gi|30794372 polybromo 1 isoform 1 [Homo sapiens] 30 8.7
gi|93102371 polybromo 1 isoform 2 [Homo sapiens] 30 8.7
gi|41281917 polybromo 1 isoform 4 [Homo sapiens] 30 8.7
>gi|29337286 eukaryotic translation initiation factor 2C, 3 isoform
b [Homo sapiens]
Length = 626
Score = 1283 bits (3320), Expect = 0.0
Identities = 626/626 (100%), Positives = 626/626 (100%)
Query: 1 MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQT 60
MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQT
Sbjct: 1 MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQT 60
Query: 61 FPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI 120
FPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI
Sbjct: 61 FPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI 120
Query: 121 KKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVL 180
KKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVL
Sbjct: 121 KKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVL 180
Query: 181 PAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQ 240
PAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQ
Sbjct: 181 PAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQ 240
Query: 241 LRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVK 300
LRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVK
Sbjct: 241 LRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVK 300
Query: 301 RVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIF 360
RVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIF
Sbjct: 301 RVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIF 360
Query: 361 LGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQF 420
LGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQF
Sbjct: 361 LGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQF 420
Query: 421 YKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHT 480
YKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHT
Sbjct: 421 YKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHT 480
Query: 481 RLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNC 540
RLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNC
Sbjct: 481 RLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNC 540
Query: 541 FTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQ 600
FTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQ
Sbjct: 541 FTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQ 600
Query: 601 SNGRDPQALAKAVQIHQDTLRTMYFA 626
SNGRDPQALAKAVQIHQDTLRTMYFA
Sbjct: 601 SNGRDPQALAKAVQIHQDTLRTMYFA 626
>gi|29294647 eukaryotic translation initiation factor 2C, 3 isoform
a [Homo sapiens]
Length = 860
Score = 1283 bits (3320), Expect = 0.0
Identities = 626/626 (100%), Positives = 626/626 (100%)
Query: 1 MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQT 60
MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQT
Sbjct: 235 MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQT 294
Query: 61 FPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI 120
FPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI
Sbjct: 295 FPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI 354
Query: 121 KKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVL 180
KKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVL
Sbjct: 355 KKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVL 414
Query: 181 PAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQ 240
PAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQ
Sbjct: 415 PAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQ 474
Query: 241 LRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVK 300
LRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVK
Sbjct: 475 LRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVK 534
Query: 301 RVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIF 360
RVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIF
Sbjct: 535 RVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIF 594
Query: 361 LGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQF 420
LGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQF
Sbjct: 595 LGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQF 654
Query: 421 YKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHT 480
YKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHT
Sbjct: 655 YKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHT 714
Query: 481 RLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNC 540
RLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNC
Sbjct: 715 RLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNC 774
Query: 541 FTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQ 600
FTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQ
Sbjct: 775 FTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQ 834
Query: 601 SNGRDPQALAKAVQIHQDTLRTMYFA 626
SNGRDPQALAKAVQIHQDTLRTMYFA
Sbjct: 835 SNGRDPQALAKAVQIHQDTLRTMYFA 860
>gi|6912352 eukaryotic translation initiation factor 2C, 1 [Homo
sapiens]
Length = 857
Score = 1174 bits (3038), Expect = 0.0
Identities = 561/626 (89%), Positives = 599/626 (95%)
Query: 1 MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQT 60
MCEVLDI NIDEQP+PLTDS RV+FTKEIKGLKVEVTHCG M+RKYRVCNVTRRPASHQT
Sbjct: 232 MCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQT 291
Query: 61 FPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI 120
FPLQLE+GQTVE TVAQYF++KY LQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI
Sbjct: 292 FPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI 351
Query: 121 KKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVL 180
KKLTDNQTSTMIKATARSAPDRQEEISRL+++A+Y DP++QEF KV+D+M VTGRVL
Sbjct: 352 KKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVL 411
Query: 181 PAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQ 240
PAP+LQYGGRNR +ATP+ GVWDMRGKQF+ G+EIK+WAIACFA Q+QCREE+LK FTDQ
Sbjct: 412 PAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQ 471
Query: 241 LRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVK 300
LRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVK
Sbjct: 472 LRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVK 531
Query: 301 RVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIF 360
RVGDTLLGMATQCVQVKNV+KTSPQTLSNLCLKINVKLGGINNILVPHQR +VFQQPVIF
Sbjct: 532 RVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIF 591
Query: 361 LGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQF 420
LGADVTHPPAGDGKKPSI AVVGSMDAHPSRYCATVRVQRPRQEII+DL+ MVRELLIQF
Sbjct: 592 LGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQF 651
Query: 421 YKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHT 480
YKSTRFKPTRIIFYRDGV EGQ Q+L+YELLAIR+ACI LEKDYQPGITYIVVQKRHHT
Sbjct: 652 YKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHT 711
Query: 481 RLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNC 540
RLFCAD+ ER+G+SGNIPAGTTVDT+ITHP+EFDFYLCSHAGIQGTSRPSHY+VLWDDN
Sbjct: 712 RLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNR 771
Query: 541 FTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQ 600
FTADELQ+LTYQLCHTYVRCTRSVSIPAPAYYA LVAFRARYHLVDKEHDS EGSH+SGQ
Sbjct: 772 FTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQ 831
Query: 601 SNGRDPQALAKAVQIHQDTLRTMYFA 626
SNGRDPQALAKAVQ+HQDTLRTMYFA
Sbjct: 832 SNGRDPQALAKAVQVHQDTLRTMYFA 857
>gi|29029593 eukaryotic translation initiation factor 2C, 4 [Homo
sapiens]
Length = 861
Score = 1125 bits (2911), Expect = 0.0
Identities = 547/638 (85%), Positives = 588/638 (92%), Gaps = 12/638 (1%)
Query: 1 MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQT 60
MCEVLDI NI+EQ +PLTDS RVKFTKEI+GLKVEVTHCG M+RKYRVCNVTRRPASHQT
Sbjct: 224 MCEVLDIQNINEQTKPLTDSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTRRPASHQT 283
Query: 61 FPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI 120
FPLQLENGQ +E TVAQYF++KY+LQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI
Sbjct: 284 FPLQLENGQAMECTVAQYFKQKYSLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI 343
Query: 121 KKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYE--TDPFVQEFQFKVRDEMAHVTGR 178
KKLTDNQTSTMIKATARSAPDRQEEISRLV+S + DP+++EF V +EM +TGR
Sbjct: 344 KKLTDNQTSTMIKATARSAPDRQEEISRLVKSNSMVGGPDPYLKEFGIVVHNEMTELTGR 403
Query: 179 VLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFT 238
VLPAPMLQYGGRN+TVATP+ GVWDMRGKQF+ G+EIK+WA+ACFA Q+QCRE++LK FT
Sbjct: 404 VLPAPMLQYGGRNKTVATPNQGVWDMRGKQFYAGIEIKVWAVACFAPQKQCREDLLKSFT 463
Query: 239 DQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAE 298
DQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMF+HLK TY GLQLI+VILPGKTPVYAE
Sbjct: 464 DQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFKHLKMTYVGLQLIVVILPGKTPVYAE 523
Query: 299 VKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPV 358
VKRVGDTLLGMATQCVQVKNV+KTSPQTLSNLCLKIN KLGGINN+LVPHQRPSVFQQPV
Sbjct: 524 VKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINAKLGGINNVLVPHQRPSVFQQPV 583
Query: 359 IFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEI----------IQD 408
IFLGADVTHPPAGDGKKPSIAAVVGSMD HPSRYCATVRVQ RQEI IQD
Sbjct: 584 IFLGADVTHPPAGDGKKPSIAAVVGSMDGHPSRYCATVRVQTSRQEISQELLYSQEVIQD 643
Query: 409 LASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPG 468
L +MVRELLIQFYKSTRFKPTRII+YR GVSEGQ +QV + EL+AIR+ACISLE+DY+PG
Sbjct: 644 LTNMVRELLIQFYKSTRFKPTRIIYYRGGVSEGQMKQVAWPELIAIRKACISLEEDYRPG 703
Query: 469 ITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSR 528
ITYIVVQKRHHTRLFCAD+TERVG+SGN+PAGTTVD+ ITHP EFDFYLCSHAGIQGTSR
Sbjct: 704 ITYIVVQKRHHTRLFCADKTERVGKSGNVPAGTTVDSTITHPSEFDFYLCSHAGIQGTSR 763
Query: 529 PSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKE 588
PSHY VLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYA LVAFRARYHLVDK+
Sbjct: 764 PSHYQVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKD 823
Query: 589 HDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA 626
HDSAEGSHVSGQSNGRDPQALAKAVQIH DT TMYFA
Sbjct: 824 HDSAEGSHVSGQSNGRDPQALAKAVQIHHDTQHTMYFA 861
>gi|29171734 eukaryotic translation initiation factor 2C, 2 [Homo
sapiens]
Length = 859
Score = 1119 bits (2895), Expect = 0.0
Identities = 536/626 (85%), Positives = 585/626 (93%)
Query: 1 MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQT 60
+CEVLD +I+EQ +PLTDS RVKFTKEIKGLKVE+THCG M+RKYRVCNVTRRPASHQT
Sbjct: 234 VCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQT 293
Query: 61 FPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI 120
FPLQ E+GQTVE TVAQYF++++ L L+YPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI
Sbjct: 294 FPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI 353
Query: 121 KKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVL 180
KKLTDNQTSTMI+ATARSAPDRQEEIS+L+RSA++ TDP+V+EF V+DEM VTGRVL
Sbjct: 354 KKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVL 413
Query: 181 PAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQ 240
P + YGGRN+ +ATP GVWDMR KQFHTG+EIK+WAIACFA QRQC E LK FT+Q
Sbjct: 414 QPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQ 473
Query: 241 LRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVK 300
LRKIS+DAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTY+GLQL++VILPGKTPVYAEVK
Sbjct: 474 LRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVK 533
Query: 301 RVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIF 360
RVGDT+LGMATQCVQ+KNV +T+PQTLSNLCLKINVKLGG+NNIL+P RP VFQQPVIF
Sbjct: 534 RVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIF 593
Query: 361 LGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQF 420
LGADVTHPPAGDGKKPSIAAVVGSMDAHP+RYCATVRVQ+ RQEIIQDLA+MVRELLIQF
Sbjct: 594 LGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQF 653
Query: 421 YKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHT 480
YKSTRFKPTRIIFYRDGVSEGQF+QVL++ELLAIREACI LEKDYQPGIT+IVVQKRHHT
Sbjct: 654 YKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHT 713
Query: 481 RLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNC 540
RLFC D+ ERVG+SGNIPAGTTVDT ITHP EFDFYLCSHAGIQGTSRPSHYHVLWDDN
Sbjct: 714 RLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNR 773
Query: 541 FTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQ 600
F++DELQ+LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSH SGQ
Sbjct: 774 FSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQ 833
Query: 601 SNGRDPQALAKAVQIHQDTLRTMYFA 626
SNGRD QALAKAVQ+HQDTLRTMYFA
Sbjct: 834 SNGRDHQALAKAVQVHQDTLRTMYFA 859
>gi|66346725 piwi-like 1 [Homo sapiens]
Length = 861
Score = 151 bits (381), Expect = 2e-36
Identities = 147/587 (25%), Positives = 252/587 (42%), Gaps = 62/587 (10%)
Query: 18 TDSHRVK--FTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTV 75
T+ H+ + +KE+ GL V + + YRV ++ TF + E +
Sbjct: 290 TEEHKFQEQVSKELIGLVVLTKY---NNKTYRVDDIDWDQNPKSTF----KKADGSEVSF 342
Query: 76 AQYFREKYTLQLKYPHLPCLQVGQEQKH----------TYLPLEVCNIVAGQRCIKKLTD 125
+Y+R++Y ++ P L V Q ++ L E+C + LTD
Sbjct: 343 LEYYRKQYNQEITDLKQPVL-VSQPKRRRGPGGTLPGPAMLIPELCYLTG-------LTD 394
Query: 126 ------NQTSTMIKATARSAPDRQEEISRLVR--SANYETDPFVQEFQFKVRDEMAHVTG 177
N + T + RQ E+ RL+ N ++++ + +G
Sbjct: 395 KMRNDFNVMKDLAVHTRLTPEQRQREVGRLIDYIHKNDNVQRELRDWGLSFDSNLLSFSG 454
Query: 178 RVLPAPMLQYGGRNRTVATPSHGVW--DMRGKQFHTGVEIKMWAIACFATQRQCREEILK 235
R+L + GG+ P W + RG + + W + T+R E
Sbjct: 455 RILQTEKIHQGGKTFDY-NPQFADWSKETRGAPLISVKPLDNWLL--IYTRRNY--EAAN 509
Query: 236 GFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVIL--PGKT 293
L K++ GM ++ + D E R L+ + I+V L +
Sbjct: 510 SLIQNLFKVTPAMGMQMRKAIMI----EVDDRTEAYLRVLQQKVTADTQIVVCLLSSNRK 565
Query: 294 PVYAEVKRVGDTLLGMATQCVQVKNVIK--TSPQTLSNLCLKINVKLGGINNILVPHQRP 351
Y +K+ T +QCV + + K T + + L++N K+GG R
Sbjct: 566 DKYDAIKKYLCTDCPTPSQCVVARTLGKQQTVMAIATKIALQMNCKMGG------ELWRV 619
Query: 352 SVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLAS 411
+ + V+ +G D H + SIA V S++ +R+ + Q QE++ L
Sbjct: 620 DIPLKLVMIVGIDCYHDMTAGRR--SIAGFVASINEGMTRWFSRCIFQDRGQELVDGLKV 677
Query: 412 MVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITY 471
++ L + + P+RII YRDGV +GQ + ++ YE+ + S+ + Y P +T
Sbjct: 678 CLQAALRAWNSCNEYMPSRIIVYRDGVGDGQLKTLVNYEVPQFLDCLKSIGRGYNPRLTV 737
Query: 472 IVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSH 531
IVV+KR +TR F + GR N GT +D ++T P +DF++ S A G+ P+H
Sbjct: 738 IVVKKRVNTRFFA----QSGGRLQNPLPGTVIDVEVTRPEWYDFFIVSQAVRSGSVSPTH 793
Query: 532 YHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAF 578
Y+V++D++ D +Q LTY+LCH Y + +PAP YAH +AF
Sbjct: 794 YNVIYDNSGLKPDHIQRLTYKLCHIYYNWPGVIRVPAPCQYAHKLAF 840
>gi|221316711 piwi-like 4 [Homo sapiens]
Length = 852
Score = 145 bits (365), Expect = 1e-34
Identities = 125/524 (23%), Positives = 237/524 (45%), Gaps = 42/524 (8%)
Query: 72 ERTVAQYFREKYTLQLKYPHLPCL-QVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTST 130
E T Y++++Y + + + P L + +++++ ++ +++ + LTD TS
Sbjct: 333 EITYVDYYKQQYDITVSDLNQPMLVSLLKKKRNDNSEAQLAHLIPELCFLTGLTDQATSD 392
Query: 131 --MIKATAR----SAPDRQEEISRLV------RSANYETDPFVQEFQFKVRDEMAHVTGR 178
++KA A S RQ+ ++RLV +A +E + + F ++ +TGR
Sbjct: 393 FQLMKAVAEKTRLSPSGRQQRLARLVDNIQRNTNARFELETWGLHFGSQIS-----LTGR 447
Query: 179 VLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFT 238
++P+ + + + D+R + + W I C E + + F
Sbjct: 448 IVPSEKILMQDHICQPVSAADWSKDIRTCKILNAQSLNTWLILC----SDRTEYVAESFL 503
Query: 239 DQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAE 298
+ LR+++ G + A V + +++ +QL++ ILP Y +
Sbjct: 504 NCLRRVAGSMGFNVDYPKIIKVQENPAAFVRAIQQYVD---PDVQLVMCILPSNQKTYYD 560
Query: 299 -VKRVGDTLLGMATQCVQVKNVIKTSPQT--LSNLCLKINVKLGG-INNILVPHQRPSVF 354
+K+ + + +QCV + + K + + +++ KLGG + + +P
Sbjct: 561 SIKKYLSSDCPVPSQCVLARTLNKQGMMMSIATKIAMQMTCKLGGELWAVEIP------- 613
Query: 355 QQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVR 414
+ ++ +G DV K + V S++ +R+ + +QR ++ L +
Sbjct: 614 LKSLMVVGIDVCKDALS--KDVMVVGCVASVNPRITRWFSRCILQRTMTDVADCLKVFMT 671
Query: 415 ELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVV 474
L ++YK P RII YR GV +GQ + ++ YE+ + + + ++ IVV
Sbjct: 672 GALNKWYKYNHDLPARIIVYRAGVGDGQLKTLIEYEVPQLLSSVAESSSNTSSRLSVIVV 731
Query: 475 QKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHV 534
+K+ R F TE N P GT VD++ T +DFYL S +GT P++Y+V
Sbjct: 732 RKKCMPRFF----TEMNRTVQNPPLGTVVDSEATRNEWYDFYLISQVACRGTVSPTYYNV 787
Query: 535 LWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAF 578
++DDN D +Q LT++LCH Y VS+PAP YAH + F
Sbjct: 788 IYDDNGLKPDHMQRLTFKLCHLYYNWPGIVSVPAPCQYAHKLTF 831
>gi|209180418 piwi-like 2 [Homo sapiens]
Length = 973
Score = 142 bits (357), Expect = 1e-33
Identities = 117/422 (27%), Positives = 205/422 (48%), Gaps = 34/422 (8%)
Query: 167 KVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQ 226
+++ ++ + GRVLP + +N + T W + + + I M A F +
Sbjct: 555 RLQKDVHKIEGRVLPMERINL--KNTSFITSQELNWVKEVTRDPSILTIPMHFWALFYPK 612
Query: 227 R---QCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSG-- 281
R Q RE + + L KI+ GM + P + + D +E R +++T
Sbjct: 613 RAMDQARELV-----NMLEKIAGPIGMRMS-PPAWVELKD--DRIETYVRTIQSTLGAEG 664
Query: 282 -LQLIIVILPG-KTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSP--QTLSNLCLKINVK 337
+Q+++ I+ G + +Y +K++ + +Q V V+ + + + + L+IN K
Sbjct: 665 KIQMVVCIIMGPRDDLYGAIKKLCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQINCK 724
Query: 338 LGG-INNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATV 396
LGG + + +P ++ ++ +G DV H P+ + S+ V S++ +++ + V
Sbjct: 725 LGGELWGVDIPLKQ-------LMVIGMDVYHDPSRGMR--SVVGFVASINLTLTKWYSRV 775
Query: 397 RVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIRE 456
Q P QEI+ L + L +FY+ P +I+ YRDGVS+GQ + V YE+ +++
Sbjct: 776 VFQMPHQEIVDSLKLCLVGSLKKFYEVNHCLPEKIVVYRDGVSDGQLKTVANYEIPQLQK 835
Query: 457 ACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFY 516
C ++YQP + VVQK+ T L+ A V + GT VD IT DFY
Sbjct: 836 -CFEAFENYQPKMVVFVVQKKISTNLYLAAPQNFVTPT----PGTVVDHTITSCEWVDFY 890
Query: 517 LCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLV 576
L +H QG P+HY + + + D +Q LT++LCH Y ++ +PAP YAH +
Sbjct: 891 LLAHHVRQGCGIPTHYVCVLNTANLSPDHMQRLTFKLCHMYWNWPGTIRVPAPCKYAHKL 950
Query: 577 AF 578
AF
Sbjct: 951 AF 952
>gi|24431985 piwi-like 2 [Homo sapiens]
Length = 973
Score = 142 bits (357), Expect = 1e-33
Identities = 117/422 (27%), Positives = 205/422 (48%), Gaps = 34/422 (8%)
Query: 167 KVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQ 226
+++ ++ + GRVLP + +N + T W + + + I M A F +
Sbjct: 555 RLQKDVHKIEGRVLPMERINL--KNTSFITSQELNWVKEVTRDPSILTIPMHFWALFYPK 612
Query: 227 R---QCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSG-- 281
R Q RE + + L KI+ GM + P + + D +E R +++T
Sbjct: 613 RAMDQARELV-----NMLEKIAGPIGMRMS-PPAWVELKD--DRIETYVRTIQSTLGAEG 664
Query: 282 -LQLIIVILPG-KTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSP--QTLSNLCLKINVK 337
+Q+++ I+ G + +Y +K++ + +Q V V+ + + + + L+IN K
Sbjct: 665 KIQMVVCIIMGPRDDLYGAIKKLCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQINCK 724
Query: 338 LGG-INNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATV 396
LGG + + +P ++ ++ +G DV H P+ + S+ V S++ +++ + V
Sbjct: 725 LGGELWGVDIPLKQ-------LMVIGMDVYHDPSRGMR--SVVGFVASINLTLTKWYSRV 775
Query: 397 RVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIRE 456
Q P QEI+ L + L +FY+ P +I+ YRDGVS+GQ + V YE+ +++
Sbjct: 776 VFQMPHQEIVDSLKLCLVGSLKKFYEVNHCLPEKIVVYRDGVSDGQLKTVANYEIPQLQK 835
Query: 457 ACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFY 516
C ++YQP + VVQK+ T L+ A V + GT VD IT DFY
Sbjct: 836 -CFEAFENYQPKMVVFVVQKKISTNLYLAAPQNFVTPT----PGTVVDHTITSCEWVDFY 890
Query: 517 LCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLV 576
L +H QG P+HY + + + D +Q LT++LCH Y ++ +PAP YAH +
Sbjct: 891 LLAHHVRQGCGIPTHYVCVLNTANLSPDHMQRLTFKLCHMYWNWPGTIRVPAPCKYAHKL 950
Query: 577 AF 578
AF
Sbjct: 951 AF 952
>gi|153792298 piwi-like 3 [Homo sapiens]
Length = 882
Score = 129 bits (324), Expect = 8e-30
Identities = 113/460 (24%), Positives = 206/460 (44%), Gaps = 31/460 (6%)
Query: 131 MIKATARSAPDRQEEISRLVRSA--NYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYG 188
+ K T S R + + + N + +Q + K V GRVL + G
Sbjct: 421 LAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVLKNANIVQG 480
Query: 189 GRNRTVATPSHGVW--DMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISK 246
R V S G W ++R + + W I ++ LKG L+ ++
Sbjct: 481 --RRMVKANSQGDWSREIRELPLLNAMPLHSWLIL-YSRSSHREAMSLKG---HLQSVTA 534
Query: 247 DAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYS-GLQLIIV-----ILPGKTPV-YAEV 299
G+ ++ ++ + ++ + T G+ ++V ILP Y +
Sbjct: 535 PMGITMKPAEMIEVDGDANSYIDTLRKYTRPTLQMGMSCLLVFKVICILPNDDKRRYDSI 594
Query: 300 KRVGDTLLGMATQCVQVKNVIKTSPQTL-SNLCLKINVKLGGINNILVPHQRPSVFQQPV 358
KR T + +QCV K + K +T+ + + ++N K+GG + Q
Sbjct: 595 KRYLCTKCPIPSQCVVKKTLEKVQARTIVTKIAQQMNCKMGGAL------WKVETDVQRT 648
Query: 359 IFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLI 418
+F+G D H ++ SIA V S +A +++ + +Q+ +E++++L ++ L
Sbjct: 649 MFVGIDCFHDIVN--RQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALD 706
Query: 419 QFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRH 478
+ K+ P +I YRDGV +GQ + +L +E + ++ + + +IVV+KR
Sbjct: 707 VWCKNESSMPHSVIVYRDGVGDGQLQALLDHEAKKMSTYLKTISPNNFT-LAFIVVKKRI 765
Query: 479 HTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDD 538
+TR F + N P GT +D ++T +DF++ S + GT P+HY+V++D
Sbjct: 766 NTRFFL----KHGSNFQNPPPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDT 821
Query: 539 NCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAF 578
+ D +Q LTY LCH Y + +PAP +YAH +A+
Sbjct: 822 IGLSPDTVQRLTYCLCHMYYNLPGIIRVPAPCHYAHKLAY 861
>gi|169217928 PREDICTED: similar to piwi like homolog 2 [Homo
sapiens]
Length = 349
Score = 49.7 bits (117), Expect = 8e-06
Identities = 60/269 (22%), Positives = 124/269 (46%), Gaps = 29/269 (10%)
Query: 167 KVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQ 226
+++ ++ + GRVLP + +N + T W + + + I M A F +
Sbjct: 49 RLQKDVHKIEGRVLPMERINL--KNTSFITSQELNWVKEVTRDPSILTIPMHFWALFYPK 106
Query: 227 R---QCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSG-- 281
R Q RE + + L KI+ GM + P + + D +E R +++T
Sbjct: 107 RAMDQARELV-----NMLEKIAGPIGMRMS-PPAWVELKD--DRIETYVRTIQSTLGAEG 158
Query: 282 -LQLIIVILPG-KTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSP--QTLSNLCLKINVK 337
+Q+++ I+ G + +Y +K++ + +Q V V+ + + + + L+IN K
Sbjct: 159 KIQMVVCIIMGPRDDLYGAIKKLCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQINCK 218
Query: 338 LGG-INNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATV 396
LGG + + +P ++ ++ +G DV H P+ + S+ V S++ +++ + V
Sbjct: 219 LGGELWGVDIPLKQ-------LMVIGMDVYHDPSRGMR--SVVGFVASINLTLTKWYSRV 269
Query: 397 RVQRPRQEIIQDLASMVRELLIQFYKSTR 425
Q P QEI+ L + L +FY++ +
Sbjct: 270 VFQMPHQEIVDSLKLCLVGSLKKFYEAAQ 298
>gi|126507091 LATS, large tumor suppressor, homolog 2 [Homo sapiens]
Length = 1088
Score = 33.9 bits (76), Expect = 0.46
Identities = 43/148 (29%), Positives = 56/148 (37%), Gaps = 32/148 (21%)
Query: 464 DYQPG------ITYIVVQKRHHTRLFCADRT---ERVGRSGNI-----PAGTTVDTDITH 509
DY PG + + V H R + A+ T E V + G I P +D D H
Sbjct: 746 DYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLD-GH 804
Query: 510 PYEFDFYLCSHAGIQGTSRPSHY----HV---------LWDD--NCFTADELQLLTYQLC 554
DF LC+ G + T +Y HV LWDD NC D L+ L +
Sbjct: 805 IKLTDFGLCT--GFRWTHNSKYYQKGSHVRQDSMEPSDLWDDVSNCRCGDRLKTLEQRAR 862
Query: 555 HTYVRCTRSVSIPAPAYYAHLVAFRARY 582
+ RC + P Y A V R Y
Sbjct: 863 KQHQRCLAHSLVGTPNYIAPEVLLRKGY 890
>gi|114199473 vacuolar protein sorting 41 isoform 2 [Homo sapiens]
Length = 829
Score = 33.9 bits (76), Expect = 0.46
Identities = 25/99 (25%), Positives = 48/99 (48%), Gaps = 9/99 (9%)
Query: 392 YCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYEL 451
YCA RPR +IIQ L+ E+ F+ Y SEG + L+Y +
Sbjct: 273 YCA-----RPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEG---ESLFY-I 323
Query: 452 LAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTER 490
++ R+ ++ E+D I +++ +K++ L A+ +++
Sbjct: 324 VSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISQK 362
>gi|114199475 vacuolar protein sorting 41 isoform 1 [Homo sapiens]
Length = 854
Score = 33.9 bits (76), Expect = 0.46
Identities = 25/99 (25%), Positives = 48/99 (48%), Gaps = 9/99 (9%)
Query: 392 YCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYEL 451
YCA RPR +IIQ L+ E+ F+ Y SEG + L+Y +
Sbjct: 298 YCA-----RPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEG---ESLFY-I 348
Query: 452 LAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTER 490
++ R+ ++ E+D I +++ +K++ L A+ +++
Sbjct: 349 VSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISQK 387
>gi|4502743 cyclin-dependent kinase 7 [Homo sapiens]
Length = 346
Score = 30.8 bits (68), Expect = 3.9
Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 3/51 (5%)
Query: 212 GVEIKMWAIACFATQRQCREEILKGFT--DQLRKISKDAGMPIQGQ-PCFC 259
GV + MWA+ C + R L G + DQL +I + G P + Q P C
Sbjct: 191 GVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMC 241
>gi|39812019 amino-terminal enhancer of split isoform a [Homo
sapiens]
Length = 264
Score = 30.0 bits (66), Expect = 6.7
Identities = 45/160 (28%), Positives = 61/160 (38%), Gaps = 13/160 (8%)
Query: 468 GITYIVVQKRH-----HTRLFCADRTERVG--RSGNIPAGTTVDTDITHPYEFDFY-LCS 519
GIT +QKR + R A TE V R G AG T FD +
Sbjct: 12 GITAAFLQKRKLRLSKNHRPARAKVTEHVRGTRPGRATAGPAASTRAAGSLFFDRWGNRG 71
Query: 520 HAGIQGTSR-PSHYHVLWDDNCFTA-DELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVA 577
AG +G+S P D+C DE QLL Q + C + S + +++
Sbjct: 72 PAGCRGSSHLPQQLKFTTSDSCDRIKDEFQLLQAQYHSLKLECDKLASEKSEMQRHYVMY 131
Query: 578 FRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQ 617
+ Y L + H AE + + NG Q L Q HQ
Sbjct: 132 YEMSYGLNIEMHKQAE---IVKRLNGICAQVLPYLSQEHQ 168
>gi|30794372 polybromo 1 isoform 1 [Homo sapiens]
Length = 1602
Score = 29.6 bits (65), Expect = 8.7
Identities = 19/87 (21%), Positives = 37/87 (42%), Gaps = 7/87 (8%)
Query: 407 QDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQ 466
QD+ SMV + ++ F + + + Y+D + VL+ LL R E +
Sbjct: 687 QDIDSMVEDFVMMFNNACTYNEPESLIYKDAL-------VLHKVLLETRRDLEGDEDSHV 739
Query: 467 PGITYIVVQKRHHTRLFCADRTERVGR 493
P +T ++ + H+ + + GR
Sbjct: 740 PNVTLLIQELIHNLFVSVMSHQDDEGR 766
>gi|93102371 polybromo 1 isoform 2 [Homo sapiens]
Length = 1582
Score = 29.6 bits (65), Expect = 8.7
Identities = 19/87 (21%), Positives = 37/87 (42%), Gaps = 7/87 (8%)
Query: 407 QDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQ 466
QD+ SMV + ++ F + + + Y+D + VL+ LL R E +
Sbjct: 719 QDIDSMVEDFVMMFNNACTYNEPESLIYKDAL-------VLHKVLLETRRDLEGDEDSHV 771
Query: 467 PGITYIVVQKRHHTRLFCADRTERVGR 493
P +T ++ + H+ + + GR
Sbjct: 772 PNVTLLIQELIHNLFVSVMSHQDDEGR 798
>gi|41281917 polybromo 1 isoform 4 [Homo sapiens]
Length = 1582
Score = 29.6 bits (65), Expect = 8.7
Identities = 19/87 (21%), Positives = 37/87 (42%), Gaps = 7/87 (8%)
Query: 407 QDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQ 466
QD+ SMV + ++ F + + + Y+D + VL+ LL R E +
Sbjct: 719 QDIDSMVEDFVMMFNNACTYNEPESLIYKDAL-------VLHKVLLETRRDLEGDEDSHV 771
Query: 467 PGITYIVVQKRHHTRLFCADRTERVGR 493
P +T ++ + H+ + + GR
Sbjct: 772 PNVTLLIQELIHNLFVSVMSHQDDEGR 798
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.136 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,357,256
Number of Sequences: 37866
Number of extensions: 1098400
Number of successful extensions: 2168
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2145
Number of HSP's gapped (non-prelim): 22
length of query: 626
length of database: 18,247,518
effective HSP length: 108
effective length of query: 518
effective length of database: 14,157,990
effective search space: 7333838820
effective search space used: 7333838820
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.