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Search of human proteins with 28416956
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28416956 GTPase, IMAP family member 8 [Homo sapiens]
(665 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28416956 GTPase, IMAP family member 8 [Homo sapiens] 1319 0.0
gi|18594498 GTPase, IMAP family member 1 [Homo sapiens] 167 3e-41
gi|28416431 GTPase, IMAP family member 2 [Homo sapiens] 165 1e-40
gi|28416949 GTPase, IMAP family member 5 [Homo sapiens] 164 3e-40
gi|56119214 GTPase, IMAP family member 6 [Homo sapiens] 158 2e-38
gi|23397516 GTPase, IMAP family member 7 [Homo sapiens] 148 1e-35
gi|8922873 GTPase, IMAP family member 4 [Homo sapiens] 147 4e-35
gi|24307899 Era-like 1 [Homo sapiens] 38 0.026
gi|239753874 PREDICTED: similar to hCG2036814 [Homo sapiens] 37 0.076
gi|239748437 PREDICTED: similar to hCG2036814 [Homo sapiens] 37 0.076
gi|239742371 PREDICTED: hypothetical protein XP_002342504 [Homo ... 37 0.076
gi|164698504 septin 9 isoform f [Homo sapiens] 35 0.17
gi|164698502 septin 9 isoform d [Homo sapiens] 35 0.17
gi|164698500 septin 9 isoform e [Homo sapiens] 35 0.17
gi|164698498 septin 9 isoform b [Homo sapiens] 35 0.17
gi|164698496 septin 9 isoform e [Homo sapiens] 35 0.17
gi|164698494 septin 9 isoform a [Homo sapiens] 35 0.17
gi|116256489 septin 9 isoform c [Homo sapiens] 35 0.17
gi|164663798 antagonist of mitotic exit network 1 homolog [Homo ... 34 0.50
gi|156602655 septin 3 isoform A [Homo sapiens] 32 1.9
gi|156602653 septin 3 isoform B [Homo sapiens] 32 1.9
gi|194353959 phosphoinositide-3-kinase, class 2 gamma polypeptid... 32 2.5
gi|21327685 YME1-like 1 isoform 1 [Homo sapiens] 32 2.5
gi|7657689 YME1-like 1 isoform 3 [Homo sapiens] 32 2.5
gi|51477696 parvin, beta isoform a [Homo sapiens] 31 3.2
gi|24430183 outer dense fiber of sperm tails 2 isoform 2 [Homo s... 31 4.2
gi|24430181 outer dense fiber of sperm tails 2 isoform 1 [Homo s... 31 4.2
gi|20127528 parvin, beta isoform b [Homo sapiens] 31 4.2
gi|239752326 PREDICTED: hypothetical protein [Homo sapiens] 30 5.5
gi|239746837 PREDICTED: hypothetical protein XP_002344237 [Homo ... 30 5.5
>gi|28416956 GTPase, IMAP family member 8 [Homo sapiens]
Length = 665
Score = 1319 bits (3413), Expect = 0.0
Identities = 665/665 (100%), Positives = 665/665 (100%)
Query: 1 MSEQSCQMSELRLLLLGKCRSGKSATGNAILGKHVFKSKFSDQTVIKMCQRESWVLRERK 60
MSEQSCQMSELRLLLLGKCRSGKSATGNAILGKHVFKSKFSDQTVIKMCQRESWVLRERK
Sbjct: 1 MSEQSCQMSELRLLLLGKCRSGKSATGNAILGKHVFKSKFSDQTVIKMCQRESWVLRERK 60
Query: 61 VVVIDTPDLFSSIACAEDKQRNIQHCLELSAPSLHALLLVIAIGHFTREDEETAKGIQQV 120
VVVIDTPDLFSSIACAEDKQRNIQHCLELSAPSLHALLLVIAIGHFTREDEETAKGIQQV
Sbjct: 61 VVVIDTPDLFSSIACAEDKQRNIQHCLELSAPSLHALLLVIAIGHFTREDEETAKGIQQV 120
Query: 121 FGAEARRHIIIVFTRKDDLGDDLLQDFIEKNKPLKQLVQDYEGRYCIFNNKTNSKDEQIT 180
FGAEARRHIIIVFTRKDDLGDDLLQDFIEKNKPLKQLVQDYEGRYCIFNNKTNSKDEQIT
Sbjct: 121 FGAEARRHIIIVFTRKDDLGDDLLQDFIEKNKPLKQLVQDYEGRYCIFNNKTNSKDEQIT 180
Query: 181 QVLELLRKVESLVNTNGGPYHVNFKTEGSRFQDCVNEAASQEGDKPQGPRERQLQSTGPE 240
QVLELLRKVESLVNTNGGPYHVNFKTEGSRFQDCVNEAASQEGDKPQGPRERQLQSTGPE
Sbjct: 181 QVLELLRKVESLVNTNGGPYHVNFKTEGSRFQDCVNEAASQEGDKPQGPRERQLQSTGPE 240
Query: 241 QNPGTSELTVLLVGKRGAGKSAAGNSILGRQAFQTGFSEQSVTQSFLSESRSWRKKKVSI 300
QNPGTSELTVLLVGKRGAGKSAAGNSILGRQAFQTGFSEQSVTQSFLSESRSWRKKKVSI
Sbjct: 241 QNPGTSELTVLLVGKRGAGKSAAGNSILGRQAFQTGFSEQSVTQSFLSESRSWRKKKVSI 300
Query: 301 IDAPDISSLKNIDSEVRKHICTGPHAFLLVTPLGFYTKNDEAVLSTIQNNFGEKFFEYMI 360
IDAPDISSLKNIDSEVRKHICTGPHAFLLVTPLGFYTKNDEAVLSTIQNNFGEKFFEYMI
Sbjct: 301 IDAPDISSLKNIDSEVRKHICTGPHAFLLVTPLGFYTKNDEAVLSTIQNNFGEKFFEYMI 360
Query: 361 ILLTRKEDLGDQDLDTFLRNSNKALYGLIQKCKNRYSAFNYRATGEEEQRQADELLEKIE 420
ILLTRKEDLGDQDLDTFLRNSNKALYGLIQKCKNRYSAFNYRATGEEEQRQADELLEKIE
Sbjct: 361 ILLTRKEDLGDQDLDTFLRNSNKALYGLIQKCKNRYSAFNYRATGEEEQRQADELLEKIE 420
Query: 421 SMVHQNGNKHCVFREKETLNIVLVGRSGTGKSATGNSILGSLVFTSRLRAQPVTKTSQSG 480
SMVHQNGNKHCVFREKETLNIVLVGRSGTGKSATGNSILGSLVFTSRLRAQPVTKTSQSG
Sbjct: 421 SMVHQNGNKHCVFREKETLNIVLVGRSGTGKSATGNSILGSLVFTSRLRAQPVTKTSQSG 480
Query: 481 RRTWDGQEVVVVDTPSFNQMLDVEKDPSRLEEEVKRCLSCCEKGDTFFVLVFQLGRFTEE 540
RRTWDGQEVVVVDTPSFNQMLDVEKDPSRLEEEVKRCLSCCEKGDTFFVLVFQLGRFTEE
Sbjct: 481 RRTWDGQEVVVVDTPSFNQMLDVEKDPSRLEEEVKRCLSCCEKGDTFFVLVFQLGRFTEE 540
Query: 541 DKTAVAKLEAIFGADFTKYAIMLFTRKEDLGAGNLEDFMKNSDNKALRRIFKKCGRRVCA 600
DKTAVAKLEAIFGADFTKYAIMLFTRKEDLGAGNLEDFMKNSDNKALRRIFKKCGRRVCA
Sbjct: 541 DKTAVAKLEAIFGADFTKYAIMLFTRKEDLGAGNLEDFMKNSDNKALRRIFKKCGRRVCA 600
Query: 601 FNNKETGQAQETQVKALLTKVNDLRKESGWSGYPHTQENVSKLIKNVQEMSQAEKLLKNL 660
FNNKETGQAQETQVKALLTKVNDLRKESGWSGYPHTQENVSKLIKNVQEMSQAEKLLKNL
Sbjct: 601 FNNKETGQAQETQVKALLTKVNDLRKESGWSGYPHTQENVSKLIKNVQEMSQAEKLLKNL 660
Query: 661 IGILQ 665
IGILQ
Sbjct: 661 IGILQ 665
>gi|18594498 GTPase, IMAP family member 1 [Homo sapiens]
Length = 306
Score = 167 bits (423), Expect = 3e-41
Identities = 91/212 (42%), Positives = 129/212 (60%), Gaps = 2/212 (0%)
Query: 434 REKETLNIVLVGRSGTGKSATGNSILGSLVFTSRLRAQPVTKTSQSGRRTWDGQEVVVVD 493
R++ T ++LVGR+G GKSATGNSILG F SRL A VT+ +G R WD V VVD
Sbjct: 23 RQESTRRLILVGRTGAGKSATGNSILGQRRFFSRLGATSVTRACTTGSRRWDKCHVEVVD 82
Query: 494 TPSFNQMLDVEKDPSRLEEEVKRCLSCCEKGDTFFVLVFQLGRFTEEDKTAVAKLEAIFG 553
TP + DP EE C G +LV QLGRFT +D+ AV ++ +FG
Sbjct: 83 TPDIFSSQVSKTDPGC--EERGHCYLLSAPGPHALLLVTQLGRFTAQDQQAVRQVRDMFG 140
Query: 554 ADFTKYAIMLFTRKEDLGAGNLEDFMKNSDNKALRRIFKKCGRRVCAFNNKETGQAQETQ 613
D K+ +++FTRKEDL G+L D++ N++N+ALR + +CG RVCAF+N+ TG+ QE Q
Sbjct: 141 EDVLKWMVIVFTRKEDLAGGSLHDYVSNTENRALRELVAECGGRVCAFDNRATGREQEAQ 200
Query: 614 VKALLTKVNDLRKESGWSGYPHTQENVSKLIK 645
V+ LL V L E + Y + ++++++
Sbjct: 201 VEQLLGMVEGLVLEHKGAHYSNEVYELAQVLR 232
Score = 140 bits (352), Expect = 5e-33
Identities = 83/205 (40%), Positives = 124/205 (60%), Gaps = 8/205 (3%)
Query: 4 QSCQMSELRLLLLGKCRSGKSATGNAILGKHVFKSKFSDQTVIKMCQRESWVLRERKVVV 63
QS Q S RL+L+G+ +GKSATGN+ILG+ F S+ +V + C S + V V
Sbjct: 21 QSRQESTRRLILVGRTGAGKSATGNSILGQRRFFSRLGATSVTRACTTGSRRWDKCHVEV 80
Query: 64 IDTPDLFSSIACAED---KQRNIQHCLELSAPSLHALLLVIAIGHFTREDEETAKGIQQV 120
+DTPD+FSS D ++R HC LSAP HALLLV +G FT +D++ + ++ +
Sbjct: 81 VDTPDIFSSQVSKTDPGCEERG--HCYLLSAPGPHALLLVTQLGRFTAQDQQAVRQVRDM 138
Query: 121 FGAEARRHIIIVFTRKDDLGDDLLQDFIE--KNKPLKQLVQDYEGRYCIFNNKTNSKDEQ 178
FG + + ++IVFTRK+DL L D++ +N+ L++LV + GR C F+N+ + EQ
Sbjct: 139 FGEDVLKWMVIVFTRKEDLAGGSLHDYVSNTENRALRELVAECGGRVCAFDNRATGR-EQ 197
Query: 179 ITQVLELLRKVESLVNTNGGPYHVN 203
QV +LL VE LV + G ++ N
Sbjct: 198 EAQVEQLLGMVEGLVLEHKGAHYSN 222
Score = 136 bits (342), Expect = 7e-32
Identities = 79/199 (39%), Positives = 117/199 (58%), Gaps = 9/199 (4%)
Query: 241 QNPGTSELTVLLVGKRGAGKSAAGNSILGRQAFQTGFSEQSVTQSFLSESRSWRKKKVSI 300
Q+ S ++LVG+ GAGKSA GNSILG++ F + SVT++ + SR W K V +
Sbjct: 21 QSRQESTRRLILVGRTGAGKSATGNSILGQRRFFSRLGATSVTRACTTGSRRWDKCHVEV 80
Query: 301 IDAPDI--SSLKNID--SEVRKHI----CTGPHAFLLVTPLGFYTKNDEAVLSTIQNNFG 352
+D PDI S + D E R H GPHA LLVT LG +T D+ + +++ FG
Sbjct: 81 VDTPDIFSSQVSKTDPGCEERGHCYLLSAPGPHALLLVTQLGRFTAQDQQAVRQVRDMFG 140
Query: 353 EKFFEYMIILLTRKEDLGDQDLDTFLRNS-NKALYGLIQKCKNRYSAFNYRATGEEEQRQ 411
E ++M+I+ TRKEDL L ++ N+ N+AL L+ +C R AF+ RATG E++ Q
Sbjct: 141 EDVLKWMVIVFTRKEDLAGGSLHDYVSNTENRALRELVAECGGRVCAFDNRATGREQEAQ 200
Query: 412 ADELLEKIESMVHQNGNKH 430
++LL +E +V ++ H
Sbjct: 201 VEQLLGMVEGLVLEHKGAH 219
>gi|28416431 GTPase, IMAP family member 2 [Homo sapiens]
Length = 337
Score = 165 bits (418), Expect = 1e-40
Identities = 85/198 (42%), Positives = 120/198 (60%), Gaps = 3/198 (1%)
Query: 436 KETLNIVLVGRSGTGKSATGNSILGSLVFTSRLRAQPVTKTSQSGRRTWDGQEVVVVDTP 495
+ L I+LVG++GTGKSA GNSIL F S+L +Q +TKT + +W +E+V++DTP
Sbjct: 20 RSELRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKTCSKSQGSWGNREIVIIDTP 79
Query: 496 SFNQMLDVEKDPSRLEEEVKRCLSCCEKGDTFFVLVFQLGRFTEEDKTAVAKLEAIFGAD 555
M + L +EV+RC G +LV QLGR+T +D+ A +++ IFG D
Sbjct: 80 D---MFSWKDHCEALYKEVQRCYLLSAPGPHVLLLVTQLGRYTSQDQQAAQRVKEIFGED 136
Query: 556 FTKYAIMLFTRKEDLGAGNLEDFMKNSDNKALRRIFKKCGRRVCAFNNKETGQAQETQVK 615
+ I+LFT KEDL G+L D+M +SDNKAL ++ CG R+CAFNN+ G Q+ QVK
Sbjct: 137 AMGHTIVLFTHKEDLNGGSLMDYMHDSDNKALSKLVAACGGRICAFNNRAEGSNQDDQVK 196
Query: 616 ALLTKVNDLRKESGWSGY 633
L+ + DL E Y
Sbjct: 197 ELMDCIEDLLMEKNGDHY 214
Score = 153 bits (387), Expect = 4e-37
Identities = 81/202 (40%), Positives = 119/202 (58%), Gaps = 3/202 (1%)
Query: 4 QSCQMSELRLLLLGKCRSGKSATGNAILGKHVFKSKFSDQTVIKMCQRESWVLRERKVVV 63
Q SELR++L+GK +GKSA GN+IL K F+SK QT+ K C + R++V+
Sbjct: 16 QCASRSELRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKTCSKSQGSWGNREIVI 75
Query: 64 IDTPDLFSSIACAEDKQRNIQHCLELSAPSLHALLLVIAIGHFTREDEETAKGIQQVFGA 123
IDTPD+FS E + +Q C LSAP H LLLV +G +T +D++ A+ ++++FG
Sbjct: 76 IDTPDMFSWKDHCEALYKEVQRCYLLSAPGPHVLLLVTQLGRYTSQDQQAAQRVKEIFGE 135
Query: 124 EARRHIIIVFTRKDDLGDDLLQDFI--EKNKPLKQLVQDYEGRYCIFNNKTNSKDEQITQ 181
+A H I++FT K+DL L D++ NK L +LV GR C FNN+ + Q Q
Sbjct: 136 DAMGHTIVLFTHKEDLNGGSLMDYMHDSDNKALSKLVAACGGRICAFNNRAEGSN-QDDQ 194
Query: 182 VLELLRKVESLVNTNGGPYHVN 203
V EL+ +E L+ G ++ N
Sbjct: 195 VKELMDCIEDLLMEKNGDHYTN 216
Score = 135 bits (341), Expect = 9e-32
Identities = 76/193 (39%), Positives = 107/193 (55%), Gaps = 8/193 (4%)
Query: 246 SELTVLLVGKRGAGKSAAGNSILGRQAFQTGFSEQSVTQSFLSESRSWRKKKVSIIDAPD 305
SEL ++LVGK G GKSAAGNSIL +QAF++ Q++T++ SW +++ IID PD
Sbjct: 21 SELRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKTCSKSQGSWGNREIVIIDTPD 80
Query: 306 ISSLKNIDSEVRKHI-------CTGPHAFLLVTPLGFYTKNDEAVLSTIQNNFGEKFFEY 358
+ S K+ + K + GPH LLVT LG YT D+ ++ FGE +
Sbjct: 81 MFSWKDHCEALYKEVQRCYLLSAPGPHVLLLVTQLGRYTSQDQQAAQRVKEIFGEDAMGH 140
Query: 359 MIILLTRKEDLGDQDLDTFLRNS-NKALYGLIQKCKNRYSAFNYRATGEEEQRQADELLE 417
I+L T KEDL L ++ +S NKAL L+ C R AFN RA G + Q EL++
Sbjct: 141 TIVLFTHKEDLNGGSLMDYMHDSDNKALSKLVAACGGRICAFNNRAEGSNQDDQVKELMD 200
Query: 418 KIESMVHQNGNKH 430
IE ++ + H
Sbjct: 201 CIEDLLMEKNGDH 213
>gi|28416949 GTPase, IMAP family member 5 [Homo sapiens]
Length = 307
Score = 164 bits (414), Expect = 3e-40
Identities = 89/195 (45%), Positives = 122/195 (62%), Gaps = 3/195 (1%)
Query: 11 LRLLLLGKCRSGKSATGNAILGKHVFKSKFSDQTVIKMCQRESWVLRERKVVVIDTPDLF 70
LR++L+GK GKSATGN+ILG+ VF+SK Q+V + CQ ++ RKV+V+DTP +F
Sbjct: 28 LRIILVGKTGCGKSATGNSILGQPVFESKLRAQSVTRTCQVKTGTWNGRKVLVVDTPSIF 87
Query: 71 SSIACAEDKQRNIQHCLELSAPSLHALLLVIAIGHFTREDEETAKGIQQVFGAEARRHII 130
S A ++ +NI C LSAP H LLLVI +G FT +D + +++VFG A RH++
Sbjct: 88 ESQADTQELYKNIGDCYLLSAPGPHVLLLVIQLGRFTAQDTVAIRKVKEVFGTGAMRHVV 147
Query: 131 IVFTRKDDLGDDLLQDFIEK--NKPLKQLVQDYEGRYCIFNNKTNSKDEQITQVLELLRK 188
I+FT K+DLG L D++ N LK LV++ E RYC FNN S +EQ Q ELL
Sbjct: 148 ILFTHKEDLGGQALDDYVANTDNCSLKDLVRECERRYCAFNN-WGSVEEQRQQQAELLAV 206
Query: 189 VESLVNTNGGPYHVN 203
+E L G +H N
Sbjct: 207 IERLGREREGSFHSN 221
Score = 160 bits (404), Expect = 5e-39
Identities = 83/189 (43%), Positives = 120/189 (63%), Gaps = 3/189 (1%)
Query: 439 LNIVLVGRSGTGKSATGNSILGSLVFTSRLRAQPVTKTSQSGRRTWDGQEVVVVDTPSFN 498
L I+LVG++G GKSATGNSILG VF S+LRAQ VT+T Q TW+G++V+VVDTPS
Sbjct: 28 LRIILVGKTGCGKSATGNSILGQPVFESKLRAQSVTRTCQVKTGTWNGRKVLVVDTPS-- 85
Query: 499 QMLDVEKDPSRLEEEVKRCLSCCEKGDTFFVLVFQLGRFTEEDKTAVAKLEAIFGADFTK 558
+ + + D L + + C G +LV QLGRFT +D A+ K++ +FG +
Sbjct: 86 -IFESQADTQELYKNIGDCYLLSAPGPHVLLLVIQLGRFTAQDTVAIRKVKEVFGTGAMR 144
Query: 559 YAIMLFTRKEDLGAGNLEDFMKNSDNKALRRIFKKCGRRVCAFNNKETGQAQETQVKALL 618
+ ++LFT KEDLG L+D++ N+DN +L+ + ++C RR CAFNN + + Q Q LL
Sbjct: 145 HVVILFTHKEDLGGQALDDYVANTDNCSLKDLVRECERRYCAFNNWGSVEEQRQQQAELL 204
Query: 619 TKVNDLRKE 627
+ L +E
Sbjct: 205 AVIERLGRE 213
Score = 130 bits (328), Expect = 3e-30
Identities = 84/237 (35%), Positives = 127/237 (53%), Gaps = 19/237 (8%)
Query: 223 GDKPQGPRERQLQSTGPEQNPGTSELTVLLVGKRGAGKSAAGNSILGRQAFQTGFSEQSV 282
G +G E L +T P L ++LVGK G GKSA GNSILG+ F++ QSV
Sbjct: 10 GTMAEGRSEDNLSATPPA-------LRIILVGKTGCGKSATGNSILGQPVFESKLRAQSV 62
Query: 283 TQSFLSESRSWRKKKVSIIDAPDISSLKNIDSEVRKHI-------CTGPHAFLLVTPLGF 335
T++ ++ +W +KV ++D P I + E+ K+I GPH LLV LG
Sbjct: 63 TRTCQVKTGTWNGRKVLVVDTPSIFESQADTQELYKNIGDCYLLSAPGPHVLLLVIQLGR 122
Query: 336 YTKNDEAVLSTIQNNFGEKFFEYMIILLTRKEDLGDQDLDTFLRNS-NKALYGLIQKCKN 394
+T D + ++ FG +++IL T KEDLG Q LD ++ N+ N +L L+++C+
Sbjct: 123 FTAQDTVAIRKVKEVFGTGAMRHVVILFTHKEDLGGQALDDYVANTDNCSLKDLVRECER 182
Query: 395 RYSAFNYRATGEEEQRQADELLEKIESMVHQ-NGNKHCVFREKETLNIVLVGRSGTG 450
RY AFN + EE+++Q ELL IE + + G+ H L+ L+ R+G G
Sbjct: 183 RYCAFNNWGSVEEQRQQQAELLAVIERLGREREGSFH---SNDLFLDAQLLQRTGAG 236
>gi|56119214 GTPase, IMAP family member 6 [Homo sapiens]
Length = 292
Score = 158 bits (399), Expect = 2e-38
Identities = 91/226 (40%), Positives = 138/226 (61%), Gaps = 16/226 (7%)
Query: 434 REKET-----LNIVLVGRSGTGKSATGNSILGSLVFTSRLRAQPVTKTSQSGRRTWDGQE 488
REKE L ++L+G++G+GKSATGNSILG VF S+L +PVTKTSQ R W G+E
Sbjct: 31 REKEQKTPRRLRLILMGKTGSGKSATGNSILGRDVFESKLSTRPVTKTSQRRSREWAGKE 90
Query: 489 VVVVDTPSFNQMLDVEKDPSRLEEEVKRCLSCCEKGDTFFVLVFQLGRFTEEDKTAVAKL 548
+ V+DTP+ +L + P + + + + + G +LV QLGRFT+ED+ V +L
Sbjct: 91 LEVIDTPN---ILSPQVSPE-VADAICQAIVLSAPGPHAVLLVTQLGRFTDEDQQVVRRL 146
Query: 549 EAIFGADFTKYAIMLFTRKEDLGAGNLEDFMKNSDNKALRRIFKKCGRRVCAFNNKETGQ 608
+ +FG + I++FTRKEDL G+LED+++ ++N+AL + RR C FNN+ G+
Sbjct: 147 QEVFGVGVLGHTILVFTRKEDLAGGSLEDYVRETNNQALAWLDVTLARRHCGFNNRAQGE 206
Query: 609 AQETQVKALLTKVNDLRKES-----GWSGYPHTQENVSKLIKNVQE 649
QE Q++ L+ KV + E+ Y +TQ+N +K +QE
Sbjct: 207 EQEAQLRELMEKVEAIMWENEGDYYSNKAYQYTQQNFR--LKELQE 250
Score = 142 bits (359), Expect = 8e-34
Identities = 87/223 (39%), Positives = 130/223 (58%), Gaps = 4/223 (1%)
Query: 11 LRLLLLGKCRSGKSATGNAILGKHVFKSKFSDQTVIKMCQRESWVLRERKVVVIDTPDLF 70
LRL+L+GK SGKSATGN+ILG+ VF+SK S + V K QR S +++ VIDTP++
Sbjct: 41 LRLILMGKTGSGKSATGNSILGRDVFESKLSTRPVTKTSQRRSREWAGKELEVIDTPNIL 100
Query: 71 SSIACAEDKQRNIQHCLELSAPSLHALLLVIAIGHFTREDEETAKGIQQVFGAEARRHII 130
S E Q + LSAP HA+LLV +G FT ED++ + +Q+VFG H I
Sbjct: 101 SPQVSPEVADAICQ-AIVLSAPGPHAVLLVTQLGRFTDEDQQVVRRLQEVFGVGVLGHTI 159
Query: 131 IVFTRKDDLGDDLLQDFIEK--NKPLKQLVQDYEGRYCIFNNKTNSKDEQITQVLELLRK 188
+VFTRK+DL L+D++ + N+ L L R+C FNN+ +EQ Q+ EL+ K
Sbjct: 160 LVFTRKEDLAGGSLEDYVRETNNQALAWLDVTLARRHCGFNNRAQG-EEQEAQLRELMEK 218
Query: 189 VESLVNTNGGPYHVNFKTEGSRFQDCVNEAASQEGDKPQGPRE 231
VE+++ N G Y+ N + ++ + E ++ + QG +
Sbjct: 219 VEAIMWENEGDYYSNKAYQYTQQNFRLKELQERQVSQGQGSED 261
Score = 134 bits (338), Expect = 2e-31
Identities = 77/187 (41%), Positives = 112/187 (59%), Gaps = 9/187 (4%)
Query: 248 LTVLLVGKRGAGKSAAGNSILGRQAFQTGFSEQSVTQSFLSESRSWRKKKVSIIDAPDIS 307
L ++L+GK G+GKSA GNSILGR F++ S + VT++ SR W K++ +ID P+I
Sbjct: 41 LRLILMGKTGSGKSATGNSILGRDVFESKLSTRPVTKTSQRRSREWAGKELEVIDTPNIL 100
Query: 308 SLKNIDSEVRKHIC-------TGPHAFLLVTPLGFYTKNDEAVLSTIQNNFGEKFFEYMI 360
S + EV IC GPHA LLVT LG +T D+ V+ +Q FG + I
Sbjct: 101 S-PQVSPEVADAICQAIVLSAPGPHAVLLVTQLGRFTDEDQQVVRRLQEVFGVGVLGHTI 159
Query: 361 ILLTRKEDLGDQDLDTFLR-NSNKALYGLIQKCKNRYSAFNYRATGEEEQRQADELLEKI 419
++ TRKEDL L+ ++R +N+AL L R+ FN RA GEE++ Q EL+EK+
Sbjct: 160 LVFTRKEDLAGGSLEDYVRETNNQALAWLDVTLARRHCGFNNRAQGEEQEAQLRELMEKV 219
Query: 420 ESMVHQN 426
E+++ +N
Sbjct: 220 EAIMWEN 226
>gi|23397516 GTPase, IMAP family member 7 [Homo sapiens]
Length = 300
Score = 148 bits (374), Expect = 1e-35
Identities = 81/192 (42%), Positives = 123/192 (64%), Gaps = 6/192 (3%)
Query: 435 EKETLNIVLVGRSGTGKSATGNSILGSLVFTSRLRAQPVTKTSQSGRRTWDGQEVVVVDT 494
E +L IVLVG++G+GKSAT N+ILG +F SR+ AQ VTK Q R W G++++VVDT
Sbjct: 5 EDRSLRIVLVGKTGSGKSATANTILGEEIFDSRIAAQAVTKNCQKASREWQGRDLLVVDT 64
Query: 495 PSFNQMLDVEKDPSRLEEEVKRCLSCCEKGDTFFVLVFQLGRFTEEDKTAVAKLEAIFGA 554
P + D ++ +E+ RC+ G VLV LGR+TEE++ VA ++A+FG
Sbjct: 65 PG---LFDTKESLDTTCKEISRCIISSCPGPHAIVLVLLLGRYTEEEQKTVALIKAVFGK 121
Query: 555 DFTKYAIMLFTRKEDLGAGNLEDFMKNSDNKALRRIFKKCGRRVCAF-NNKETGQAQ-ET 612
K+ ++LFTRKE+L + DF+ ++D L+ I K+CG R CAF N+K+T +A+ E+
Sbjct: 122 SAMKHMVILFTRKEELEGQSFHDFIADAD-VGLKSIVKECGNRCCAFSNSKKTSKAEKES 180
Query: 613 QVKALLTKVNDL 624
QV+ L+ + +
Sbjct: 181 QVQELVELIEKM 192
Score = 144 bits (363), Expect = 3e-34
Identities = 77/192 (40%), Positives = 119/192 (61%), Gaps = 2/192 (1%)
Query: 11 LRLLLLGKCRSGKSATGNAILGKHVFKSKFSDQTVIKMCQRESWVLRERKVVVIDTPDLF 70
LR++L+GK SGKSAT N ILG+ +F S+ + Q V K CQ+ S + R ++V+DTP LF
Sbjct: 9 LRIVLVGKTGSGKSATANTILGEEIFDSRIAAQAVTKNCQKASREWQGRDLLVVDTPGLF 68
Query: 71 SSIACAEDKQRNIQHCLELSAPSLHALLLVIAIGHFTREDEETAKGIQQVFGAEARRHII 130
+ + + I C+ S P HA++LV+ +G +T E+++T I+ VFG A +H++
Sbjct: 69 DTKESLDTTCKEISRCIISSCPGPHAIVLVLLLGRYTEEEQKTVALIKAVFGKSAMKHMV 128
Query: 131 IVFTRKDDLGDDLLQDFI-EKNKPLKQLVQDYEGRYCIF-NNKTNSKDEQITQVLELLRK 188
I+FTRK++L DFI + + LK +V++ R C F N+K SK E+ +QV EL+
Sbjct: 129 ILFTRKEELEGQSFHDFIADADVGLKSIVKECGNRCCAFSNSKKTSKAEKESQVQELVEL 188
Query: 189 VESLVNTNGGPY 200
+E +V N G Y
Sbjct: 189 IEKMVQCNEGAY 200
Score = 122 bits (306), Expect = 1e-27
Identities = 69/188 (36%), Positives = 112/188 (59%), Gaps = 9/188 (4%)
Query: 248 LTVLLVGKRGAGKSAAGNSILGRQAFQTGFSEQSVTQSFLSESRSWRKKKVSIIDAPDI- 306
L ++LVGK G+GKSA N+ILG + F + + Q+VT++ SR W+ + + ++D P +
Sbjct: 9 LRIVLVGKTGSGKSATANTILGEEIFDSRIAAQAVTKNCQKASREWQGRDLLVVDTPGLF 68
Query: 307 ---SSLKNIDSEVRKHI---CTGPHAFLLVTPLGFYTKNDEAVLSTIQNNFGEKFFEYMI 360
SL E+ + I C GPHA +LV LG YT+ ++ ++ I+ FG+ ++M+
Sbjct: 69 DTKESLDTTCKEISRCIISSCPGPHAIVLVLLLGRYTEEEQKTVALIKAVFGKSAMKHMV 128
Query: 361 ILLTRKEDLGDQDLDTFLRNSNKALYGLIQKCKNRYSAF-NYRATGE-EEQRQADELLEK 418
IL TRKE+L Q F+ +++ L ++++C NR AF N + T + E++ Q EL+E
Sbjct: 129 ILFTRKEELEGQSFHDFIADADVGLKSIVKECGNRCCAFSNSKKTSKAEKESQVQELVEL 188
Query: 419 IESMVHQN 426
IE MV N
Sbjct: 189 IEKMVQCN 196
>gi|8922873 GTPase, IMAP family member 4 [Homo sapiens]
Length = 329
Score = 147 bits (370), Expect = 4e-35
Identities = 80/199 (40%), Positives = 119/199 (59%), Gaps = 8/199 (4%)
Query: 236 STGP-EQNPGTSELTVLLVGKRGAGKSAAGNSILGRQAFQTGFSEQSVTQSFLSESRSWR 294
S GP Q P S+L ++LVGK GAGKSA GNSILGR+ F +G + +S+T+ S SW+
Sbjct: 18 SYGPGRQEPRNSQLRIVLVGKTGAGKSATGNSILGRKVFHSGTAAKSITKKCEKRSSSWK 77
Query: 295 KKKVSIIDAPDISSLKNIDSEVRKHICT-------GPHAFLLVTPLGFYTKNDEAVLSTI 347
+ ++ ++D P I + ++E K I GPHA LLV PLG YT+ + I
Sbjct: 78 ETELVVVDTPGIFDTEVPNAETSKEIIRCILLTSPGPHALLLVVPLGRYTEEEHKATEKI 137
Query: 348 QNNFGEKFFEYMIILLTRKEDLGDQDLDTFLRNSNKALYGLIQKCKNRYSAFNYRATGEE 407
FGE+ +MI++ TRK+DLGD +L +LR + + + L+ +RY A N +ATG E
Sbjct: 138 LKMFGERARSFMILIFTRKDDLGDTNLHDYLREAPEDIQDLMDIFGDRYCALNNKATGAE 197
Query: 408 EQRQADELLEKIESMVHQN 426
++ Q +LL I+ +V +N
Sbjct: 198 QEAQRAQLLGLIQRVVREN 216
Score = 144 bits (362), Expect = 3e-34
Identities = 81/230 (35%), Positives = 135/230 (58%), Gaps = 2/230 (0%)
Query: 4 QSCQMSELRLLLLGKCRSGKSATGNAILGKHVFKSKFSDQTVIKMCQRESWVLRERKVVV 63
Q + S+LR++L+GK +GKSATGN+ILG+ VF S + +++ K C++ S +E ++VV
Sbjct: 24 QEPRNSQLRIVLVGKTGAGKSATGNSILGRKVFHSGTAAKSITKKCEKRSSSWKETELVV 83
Query: 64 IDTPDLFSSIACAEDKQRNIQHCLELSAPSLHALLLVIAIGHFTREDEETAKGIQQVFGA 123
+DTP +F + + + I C+ L++P HALLLV+ +G +T E+ + + I ++FG
Sbjct: 84 VDTPGIFDTEVPNAETSKEIIRCILLTSPGPHALLLVVPLGRYTEEEHKATEKILKMFGE 143
Query: 124 EARRHIIIVFTRKDDLGDDLLQDFI-EKNKPLKQLVQDYEGRYCIFNNKTNSKDEQITQV 182
AR +I++FTRKDDLGD L D++ E + ++ L+ + RYC NNK EQ Q
Sbjct: 144 RARSFMILIFTRKDDLGDTNLHDYLREAPEDIQDLMDIFGDRYCALNNKATGA-EQEAQR 202
Query: 183 LELLRKVESLVNTNGGPYHVNFKTEGSRFQDCVNEAASQEGDKPQGPRER 232
+LL ++ +V N + N + + + A QE + + RE+
Sbjct: 203 AQLLGLIQRVVRENKEGCYTNRMYQRAEEEIQKQTQAMQELHRVELEREK 252
Score = 140 bits (354), Expect = 3e-33
Identities = 87/223 (39%), Positives = 125/223 (56%), Gaps = 13/223 (5%)
Query: 439 LNIVLVGRSGTGKSATGNSILGSLVFTSRLRAQPVTKTSQSGRRTWDGQEVVVVDTPSFN 498
L IVLVG++G GKSATGNSILG VF S A+ +TK + +W E+VVVDTP
Sbjct: 31 LRIVLVGKTGAGKSATGNSILGRKVFHSGTAAKSITKKCEKRSSSWKETELVVVDTPG-- 88
Query: 499 QMLDVEKDPSRLEEEVKRCLSCCEKGDTFFVLVFQLGRFTEEDKTAVAKLEAIFGADFTK 558
+ D E + +E+ RC+ G +LV LGR+TEE+ A K+ +FG
Sbjct: 89 -IFDTEVPNAETSKEIIRCILLTSPGPHALLLVVPLGRYTEEEHKATEKILKMFGERARS 147
Query: 559 YAIMLFTRKEDLGAGNLEDFMKNS--DNKALRRIFKKCGRRVCAFNNKETG---QAQETQ 613
+ I++FTRK+DLG NL D+++ + D + L IF G R CA NNK TG +AQ Q
Sbjct: 148 FMILIFTRKDDLGDTNLHDYLREAPEDIQDLMDIF---GDRYCALNNKATGAEQEAQRAQ 204
Query: 614 VKALLTKVNDLRKESGWSG--YPHTQENVSKLIKNVQEMSQAE 654
+ L+ +V KE ++ Y +E + K + +QE+ + E
Sbjct: 205 LLGLIQRVVRENKEGCYTNRMYQRAEEEIQKQTQAMQELHRVE 247
>gi|24307899 Era-like 1 [Homo sapiens]
Length = 437
Score = 38.1 bits (87), Expect = 0.026
Identities = 29/81 (35%), Positives = 44/81 (54%), Gaps = 10/81 (12%)
Query: 11 LRLLLLGKCRSGKSATGNAILGKHVFKSKFSDQTVIKMCQRESWVL-RERKVVVIDTPDL 69
LR++LLG +GKS N +LG+ VF S + CQ + +E +V+++DTP +
Sbjct: 114 LRVVLLGAPNAGKSTLSNQLLGRKVF--PVSRKVHTTRCQALGVITEKETQVILLDTPGI 171
Query: 70 FSSIACAEDKQRNIQHCLELS 90
S KQ+ +H LELS
Sbjct: 172 IS-----PGKQK--RHHLELS 185
Score = 32.7 bits (73), Expect = 1.1
Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 1/57 (1%)
Query: 439 LNIVLVGRSGTGKSATGNSILGSLVFTSRLRAQPVTKTSQSGRRTWDGQEVVVVDTP 495
L +VL+G GKS N +LG VF R T+ G T +V+++DTP
Sbjct: 114 LRVVLLGAPNAGKSTLSNQLLGRKVFPVS-RKVHTTRCQALGVITEKETQVILLDTP 169
Score = 32.0 bits (71), Expect = 1.9
Identities = 20/70 (28%), Positives = 32/70 (45%), Gaps = 1/70 (1%)
Query: 239 PEQNPGTSELTVLLVGKRGAGKSAAGNSILGRQAFQTGFSEQSVTQSFLSESRSWRKKKV 298
P+ + L V+L+G AGKS N +LGR+ F + L ++ +V
Sbjct: 105 PDMPENSRVLRVVLLGAPNAGKSTLSNQLLGRKVFPVSRKVHTTRCQALGVITE-KETQV 163
Query: 299 SIIDAPDISS 308
++D P I S
Sbjct: 164 ILLDTPGIIS 173
>gi|239753874 PREDICTED: similar to hCG2036814 [Homo sapiens]
Length = 547
Score = 36.6 bits (83), Expect = 0.076
Identities = 43/168 (25%), Positives = 65/168 (38%), Gaps = 24/168 (14%)
Query: 364 TRKEDLGDQDLDTFLRNSNKALYGLIQKCKNRYSAFNYRATGEEEQRQADELLEKI-ESM 422
T + DL + L N G Q + + + E+R E + K ++M
Sbjct: 217 TERNDLVQMSVSQLLLFENGNFQGTSQNFRKKVKVHMKEQLCQGERRLCGESIFKTGKAM 276
Query: 423 VHQNGNKHCVFREKETLNIVLVGRSGTGKSATGNSILGSLVFTSRLRAQPVTKTSQSGRR 482
N K +N+ L G + +GKS+ GN +LGS F S VT GR
Sbjct: 277 TDPN---------KMIINLALFGMTQSGKSSAGNILLGSTDFHSSFAPCSVTTCCSLGRS 327
Query: 483 TW-------DGQEVV----VVDTPSFNQMLDVEKDPSRLEEEVKRCLS 519
G EV V+DTP + +K +++EVK L+
Sbjct: 328 CHLHSFMRRGGLEVALQVQVLDTPGYPHSRLSKK---YVKQEVKEALA 372
Score = 35.0 bits (79), Expect = 0.22
Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 13/103 (12%)
Query: 11 LRLLLLGKCRSGKSATGNAILGKHVFKSKFSDQTVI------KMCQRESWVLR-----ER 59
+ L L G +SGKS+ GN +LG F S F+ +V + C S++ R
Sbjct: 284 INLALFGMTQSGKSSAGNILLGSTDFHSSFAPCSVTTCCSLGRSCHLHSFMRRGGLEVAL 343
Query: 60 KVVVIDTPDLFSSIACAEDKQRNIQHCL--ELSAPSLHALLLV 100
+V V+DTP S + ++ ++ L LH LLV
Sbjct: 344 QVQVLDTPGYPHSRLSKKYVKQEVKEALAHHFGQGGLHLALLV 386
Score = 33.1 bits (74), Expect = 0.85
Identities = 30/109 (27%), Positives = 46/109 (42%), Gaps = 20/109 (18%)
Query: 242 NPGTSELTVLLVGKRGAGKSAAGNSILGRQAFQTGFSEQSVT-----------QSFLSES 290
+P + + L G +GKS+AGN +LG F + F+ SVT SF+
Sbjct: 278 DPNKMIINLALFGMTQSGKSSAGNILLGSTDFHSSFAPCSVTTCCSLGRSCHLHSFMRRG 337
Query: 291 RSWRKKKVSIIDAPDIS----SLKNIDSEVRKHIC-----TGPHAFLLV 330
+V ++D P S K + EV++ + G H LLV
Sbjct: 338 GLEVALQVQVLDTPGYPHSRLSKKYVKQEVKEALAHHFGQGGLHLALLV 386
>gi|239748437 PREDICTED: similar to hCG2036814 [Homo sapiens]
Length = 547
Score = 36.6 bits (83), Expect = 0.076
Identities = 43/168 (25%), Positives = 65/168 (38%), Gaps = 24/168 (14%)
Query: 364 TRKEDLGDQDLDTFLRNSNKALYGLIQKCKNRYSAFNYRATGEEEQRQADELLEKI-ESM 422
T + DL + L N G Q + + + E+R E + K ++M
Sbjct: 217 TERNDLVQMSVSQLLLFENGNFQGTSQNFRKKVKVHMKEQLCQGERRLCGESIFKTGKAM 276
Query: 423 VHQNGNKHCVFREKETLNIVLVGRSGTGKSATGNSILGSLVFTSRLRAQPVTKTSQSGRR 482
N K +N+ L G + +GKS+ GN +LGS F S VT GR
Sbjct: 277 TDPN---------KMIINLALFGMTQSGKSSAGNILLGSTDFHSSFAPCSVTTCCSLGRS 327
Query: 483 TW-------DGQEVV----VVDTPSFNQMLDVEKDPSRLEEEVKRCLS 519
G EV V+DTP + +K +++EVK L+
Sbjct: 328 CHLHSFMRRGGLEVALQVQVLDTPGYPHSRLSKK---YVKQEVKEALA 372
Score = 35.0 bits (79), Expect = 0.22
Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 13/103 (12%)
Query: 11 LRLLLLGKCRSGKSATGNAILGKHVFKSKFSDQTVI------KMCQRESWVLR-----ER 59
+ L L G +SGKS+ GN +LG F S F+ +V + C S++ R
Sbjct: 284 INLALFGMTQSGKSSAGNILLGSTDFHSSFAPCSVTTCCSLGRSCHLHSFMRRGGLEVAL 343
Query: 60 KVVVIDTPDLFSSIACAEDKQRNIQHCL--ELSAPSLHALLLV 100
+V V+DTP S + ++ ++ L LH LLV
Sbjct: 344 QVQVLDTPGYPHSRLSKKYVKQEVKEALAHHFGQGGLHLALLV 386
Score = 33.1 bits (74), Expect = 0.85
Identities = 30/109 (27%), Positives = 46/109 (42%), Gaps = 20/109 (18%)
Query: 242 NPGTSELTVLLVGKRGAGKSAAGNSILGRQAFQTGFSEQSVT-----------QSFLSES 290
+P + + L G +GKS+AGN +LG F + F+ SVT SF+
Sbjct: 278 DPNKMIINLALFGMTQSGKSSAGNILLGSTDFHSSFAPCSVTTCCSLGRSCHLHSFMRRG 337
Query: 291 RSWRKKKVSIIDAPDIS----SLKNIDSEVRKHIC-----TGPHAFLLV 330
+V ++D P S K + EV++ + G H LLV
Sbjct: 338 GLEVALQVQVLDTPGYPHSRLSKKYVKQEVKEALAHHFGQGGLHLALLV 386
>gi|239742371 PREDICTED: hypothetical protein XP_002342504 [Homo
sapiens]
Length = 547
Score = 36.6 bits (83), Expect = 0.076
Identities = 43/168 (25%), Positives = 65/168 (38%), Gaps = 24/168 (14%)
Query: 364 TRKEDLGDQDLDTFLRNSNKALYGLIQKCKNRYSAFNYRATGEEEQRQADELLEKI-ESM 422
T + DL + L N G Q + + + E+R E + K ++M
Sbjct: 217 TERNDLVQMSVSQLLLFENGNFQGTSQNFRKKVKVHMKEQLCQGERRLCGESIFKTGKAM 276
Query: 423 VHQNGNKHCVFREKETLNIVLVGRSGTGKSATGNSILGSLVFTSRLRAQPVTKTSQSGRR 482
N K +N+ L G + +GKS+ GN +LGS F S VT GR
Sbjct: 277 TDPN---------KMIINLALFGMTQSGKSSAGNILLGSTDFHSSFAPCSVTTCCSLGRS 327
Query: 483 TW-------DGQEVV----VVDTPSFNQMLDVEKDPSRLEEEVKRCLS 519
G EV V+DTP + +K +++EVK L+
Sbjct: 328 CHLHSFMRRGGLEVALQVQVLDTPGYPHSRLSKK---YVKQEVKEALA 372
Score = 35.0 bits (79), Expect = 0.22
Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 13/103 (12%)
Query: 11 LRLLLLGKCRSGKSATGNAILGKHVFKSKFSDQTVI------KMCQRESWVLR-----ER 59
+ L L G +SGKS+ GN +LG F S F+ +V + C S++ R
Sbjct: 284 INLALFGMTQSGKSSAGNILLGSTDFHSSFAPCSVTTCCSLGRSCHLHSFMRRGGLEVAL 343
Query: 60 KVVVIDTPDLFSSIACAEDKQRNIQHCL--ELSAPSLHALLLV 100
+V V+DTP S + ++ ++ L LH LLV
Sbjct: 344 QVQVLDTPGYPHSRLSKKYVKQEVKEALAHHFGQGGLHLALLV 386
Score = 33.1 bits (74), Expect = 0.85
Identities = 30/109 (27%), Positives = 46/109 (42%), Gaps = 20/109 (18%)
Query: 242 NPGTSELTVLLVGKRGAGKSAAGNSILGRQAFQTGFSEQSVT-----------QSFLSES 290
+P + + L G +GKS+AGN +LG F + F+ SVT SF+
Sbjct: 278 DPNKMIINLALFGMTQSGKSSAGNILLGSTDFHSSFAPCSVTTCCSLGRSCHLHSFMRRG 337
Query: 291 RSWRKKKVSIIDAPDIS----SLKNIDSEVRKHIC-----TGPHAFLLV 330
+V ++D P S K + EV++ + G H LLV
Sbjct: 338 GLEVALQVQVLDTPGYPHSRLSKKYVKQEVKEALAHHFGQGGLHLALLV 386
>gi|164698504 septin 9 isoform f [Homo sapiens]
Length = 335
Score = 35.4 bits (80), Expect = 0.17
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 15/97 (15%)
Query: 419 IESMVHQNGNKHCVFREKETLNIVLVGRSGTGKSATGNSILGSLVFTSRLRAQP-----V 473
I+S++ Q K ++ NI++VG+SG GKS N++ S + SR QP +
Sbjct: 30 IDSILEQMRRK--AMKQGFEFNIMVVGQSGLGKSTLINTLFKSKI--SRKSVQPTSEERI 85
Query: 474 TKTSQSGRRTWDGQE------VVVVDTPSFNQMLDVE 504
KT + T D +E + V+DTP F ++ E
Sbjct: 86 PKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNE 122
>gi|164698502 septin 9 isoform d [Homo sapiens]
Length = 474
Score = 35.4 bits (80), Expect = 0.17
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 15/97 (15%)
Query: 419 IESMVHQNGNKHCVFREKETLNIVLVGRSGTGKSATGNSILGSLVFTSRLRAQP-----V 473
I+S++ Q K ++ NI++VG+SG GKS N++ S + SR QP +
Sbjct: 169 IDSILEQMRRK--AMKQGFEFNIMVVGQSGLGKSTLINTLFKSKI--SRKSVQPTSEERI 224
Query: 474 TKTSQSGRRTWDGQE------VVVVDTPSFNQMLDVE 504
KT + T D +E + V+DTP F ++ E
Sbjct: 225 PKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNE 261
>gi|164698500 septin 9 isoform e [Homo sapiens]
Length = 422
Score = 35.4 bits (80), Expect = 0.17
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 15/97 (15%)
Query: 419 IESMVHQNGNKHCVFREKETLNIVLVGRSGTGKSATGNSILGSLVFTSRLRAQP-----V 473
I+S++ Q K ++ NI++VG+SG GKS N++ S + SR QP +
Sbjct: 117 IDSILEQMRRK--AMKQGFEFNIMVVGQSGLGKSTLINTLFKSKI--SRKSVQPTSEERI 172
Query: 474 TKTSQSGRRTWDGQE------VVVVDTPSFNQMLDVE 504
KT + T D +E + V+DTP F ++ E
Sbjct: 173 PKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNE 209
>gi|164698498 septin 9 isoform b [Homo sapiens]
Length = 579
Score = 35.4 bits (80), Expect = 0.17
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 15/97 (15%)
Query: 419 IESMVHQNGNKHCVFREKETLNIVLVGRSGTGKSATGNSILGSLVFTSRLRAQP-----V 473
I+S++ Q K ++ NI++VG+SG GKS N++ S + SR QP +
Sbjct: 274 IDSILEQMRRK--AMKQGFEFNIMVVGQSGLGKSTLINTLFKSKI--SRKSVQPTSEERI 329
Query: 474 TKTSQSGRRTWDGQE------VVVVDTPSFNQMLDVE 504
KT + T D +E + V+DTP F ++ E
Sbjct: 330 PKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNE 366
>gi|164698496 septin 9 isoform e [Homo sapiens]
Length = 422
Score = 35.4 bits (80), Expect = 0.17
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 15/97 (15%)
Query: 419 IESMVHQNGNKHCVFREKETLNIVLVGRSGTGKSATGNSILGSLVFTSRLRAQP-----V 473
I+S++ Q K ++ NI++VG+SG GKS N++ S + SR QP +
Sbjct: 117 IDSILEQMRRK--AMKQGFEFNIMVVGQSGLGKSTLINTLFKSKI--SRKSVQPTSEERI 172
Query: 474 TKTSQSGRRTWDGQE------VVVVDTPSFNQMLDVE 504
KT + T D +E + V+DTP F ++ E
Sbjct: 173 PKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNE 209
>gi|164698494 septin 9 isoform a [Homo sapiens]
Length = 586
Score = 35.4 bits (80), Expect = 0.17
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 15/97 (15%)
Query: 419 IESMVHQNGNKHCVFREKETLNIVLVGRSGTGKSATGNSILGSLVFTSRLRAQP-----V 473
I+S++ Q K ++ NI++VG+SG GKS N++ S + SR QP +
Sbjct: 281 IDSILEQMRRK--AMKQGFEFNIMVVGQSGLGKSTLINTLFKSKI--SRKSVQPTSEERI 336
Query: 474 TKTSQSGRRTWDGQE------VVVVDTPSFNQMLDVE 504
KT + T D +E + V+DTP F ++ E
Sbjct: 337 PKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNE 373
>gi|116256489 septin 9 isoform c [Homo sapiens]
Length = 568
Score = 35.4 bits (80), Expect = 0.17
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 15/97 (15%)
Query: 419 IESMVHQNGNKHCVFREKETLNIVLVGRSGTGKSATGNSILGSLVFTSRLRAQP-----V 473
I+S++ Q K ++ NI++VG+SG GKS N++ S + SR QP +
Sbjct: 263 IDSILEQMRRK--AMKQGFEFNIMVVGQSGLGKSTLINTLFKSKI--SRKSVQPTSEERI 318
Query: 474 TKTSQSGRRTWDGQE------VVVVDTPSFNQMLDVE 504
KT + T D +E + V+DTP F ++ E
Sbjct: 319 PKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNE 355
>gi|164663798 antagonist of mitotic exit network 1 homolog [Homo
sapiens]
Length = 258
Score = 33.9 bits (76), Expect = 0.50
Identities = 26/94 (27%), Positives = 40/94 (42%)
Query: 4 QSCQMSELRLLLLGKCRSGKSATGNAILGKHVFKSKFSDQTVIKMCQRESWVLRERKVVV 63
+SC +S+ LL L CR K NA G V + + V C +R +
Sbjct: 69 RSCDISDAALLHLSNCRKLKKLNLNASKGNRVSVTSEGIKAVASSCSYLHEASLKRCCNL 128
Query: 64 IDTPDLFSSIACAEDKQRNIQHCLELSAPSLHAL 97
D + ++ C K ++ CL ++ SLHAL
Sbjct: 129 TDEGVVALALNCQLLKIIDLGGCLSITDVSLHAL 162
>gi|156602655 septin 3 isoform A [Homo sapiens]
Length = 358
Score = 32.0 bits (71), Expect = 1.9
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 9/74 (12%)
Query: 440 NIVLVGRSGTGKSATGNSILGSLV---FTSRLRAQPVTKTSQ---SGRRTWDG---QEVV 490
NI++VG+SG GKS N++ S V +S R + + KT + G +G ++
Sbjct: 63 NIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLT 122
Query: 491 VVDTPSFNQMLDVE 504
V+DTP F ++ E
Sbjct: 123 VIDTPGFGDQINNE 136
>gi|156602653 septin 3 isoform B [Homo sapiens]
Length = 350
Score = 32.0 bits (71), Expect = 1.9
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 9/74 (12%)
Query: 440 NIVLVGRSGTGKSATGNSILGSLV---FTSRLRAQPVTKTSQ---SGRRTWDG---QEVV 490
NI++VG+SG GKS N++ S V +S R + + KT + G +G ++
Sbjct: 63 NIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLT 122
Query: 491 VVDTPSFNQMLDVE 504
V+DTP F ++ E
Sbjct: 123 VIDTPGFGDQINNE 136
>gi|194353959 phosphoinositide-3-kinase, class 2 gamma polypeptide
[Homo sapiens]
Length = 1445
Score = 31.6 bits (70), Expect = 2.5
Identities = 21/69 (30%), Positives = 36/69 (52%), Gaps = 9/69 (13%)
Query: 457 SILGSLVFTSRLRAQPVTKTSQSGRRTWDGQE----VVVVDTPSFN---QMLDVEKDPSR 509
SILGS++F+ L+++P + G WD + + +D P+ D E++ S
Sbjct: 588 SILGSMLFSMTLQSEPPVEMITPG--VWDVSQPSPVTLQIDFPATGWEYMKPDSEENRSN 645
Query: 510 LEEEVKRCL 518
LEE +K C+
Sbjct: 646 LEEPLKECI 654
>gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]
Length = 773
Score = 31.6 bits (70), Expect = 2.5
Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 30/146 (20%)
Query: 337 TKN-DEAVLSTIQNNFGEKFFEYMIILLTRKEDLGDQDLDTFLRNSNKALYGLIQKCKNR 395
TKN EA + F E F + + + L L F+ L+G+ KN
Sbjct: 257 TKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLILFVL----LLFGIYGLLKNP 312
Query: 396 YSAFNYRAT---------------------GEEEQRQADELLEKIESMVHQNGNKHCVFR 434
+ + +R T G EE +Q EL E +E + +N K +
Sbjct: 313 FLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQ--ELQEVVEFL--KNPQKFTILG 368
Query: 435 EKETLNIVLVGRSGTGKSATGNSILG 460
K I+LVG GTGK+ ++ G
Sbjct: 369 GKLPKGILLVGPPGTGKTLLARAVAG 394
>gi|7657689 YME1-like 1 isoform 3 [Homo sapiens]
Length = 716
Score = 31.6 bits (70), Expect = 2.5
Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 30/146 (20%)
Query: 337 TKN-DEAVLSTIQNNFGEKFFEYMIILLTRKEDLGDQDLDTFLRNSNKALYGLIQKCKNR 395
TKN EA + F E F + + + L L F+ L+G+ KN
Sbjct: 200 TKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLILFVL----LLFGIYGLLKNP 255
Query: 396 YSAFNYRAT---------------------GEEEQRQADELLEKIESMVHQNGNKHCVFR 434
+ + +R T G EE +Q EL E +E + +N K +
Sbjct: 256 FLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQ--ELQEVVEFL--KNPQKFTILG 311
Query: 435 EKETLNIVLVGRSGTGKSATGNSILG 460
K I+LVG GTGK+ ++ G
Sbjct: 312 GKLPKGILLVGPPGTGKTLLARAVAG 337
>gi|51477696 parvin, beta isoform a [Homo sapiens]
Length = 397
Score = 31.2 bits (69), Expect = 3.2
Identities = 42/184 (22%), Positives = 73/184 (39%), Gaps = 40/184 (21%)
Query: 457 SILGSLVFTSRLRAQPVTKTSQSGRRTWDGQEVVVVDTPSFNQMLDVEKDPSRLEE-EVK 515
S+ GSL+ S ++ +Q G + +++P ++DV + ++LEE E +
Sbjct: 47 SLAGSLLPGSDRSGVETSEYAQGGVSDLQEEGKNAINSPMSPALVDVHPEDTQLEENEER 106
Query: 516 RCLSCCEKGDTFF-----VLVFQLGRFTEEDKTAVAKLEAIFGADFTKYAIMLFTRKEDL 570
+ K D F VL+ + E++ V +LE EDL
Sbjct: 107 TMIDPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLE------------------EDL 148
Query: 571 GAGNLEDFMKNSDNKALRRIFKK---CGRRVCAFNNKETGQAQETQVKALLTKVNDLRKE 627
D + L+++ +K C V E GQ Q+ Q +L V+DL +
Sbjct: 149 -----------YDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQKLQ--TVLEAVHDLLRP 195
Query: 628 SGWS 631
GW+
Sbjct: 196 RGWA 199
>gi|24430183 outer dense fiber of sperm tails 2 isoform 2 [Homo
sapiens]
Length = 638
Score = 30.8 bits (68), Expect = 4.2
Identities = 12/35 (34%), Positives = 22/35 (62%)
Query: 79 KQRNIQHCLELSAPSLHALLLVIAIGHFTREDEET 113
K +N HCLE++ PS L+ V+ + + ED+++
Sbjct: 62 KTKNPPHCLEITPPSSEKLVSVMRLSDLSTEDDDS 96
>gi|24430181 outer dense fiber of sperm tails 2 isoform 1 [Homo
sapiens]
Length = 805
Score = 30.8 bits (68), Expect = 4.2
Identities = 12/35 (34%), Positives = 22/35 (62%)
Query: 79 KQRNIQHCLELSAPSLHALLLVIAIGHFTREDEET 113
K +N HCLE++ PS L+ V+ + + ED+++
Sbjct: 57 KTKNPPHCLEITPPSSEKLVSVMRLSDLSTEDDDS 91
>gi|20127528 parvin, beta isoform b [Homo sapiens]
Length = 364
Score = 30.8 bits (68), Expect = 4.2
Identities = 43/186 (23%), Positives = 73/186 (39%), Gaps = 50/186 (26%)
Query: 457 SILGSL--VFTSRLRAQPVTKTSQSGRRTWDGQEVVVVDTPSFNQMLDVEKDPSRLEEEV 514
S LG L + RA+ V+ + G+ +++P ++DV + ++LEE
Sbjct: 20 SFLGKLGGTLARKRRAREVSDLQEEGKNA--------INSPMSPALVDVHPEDTQLEENE 71
Query: 515 KRCL-SCCEKGDTFF-----VLVFQLGRFTEEDKTAVAKLEAIFGADFTKYAIMLFTRKE 568
+R + K D F VL+ + E++ V +LE E
Sbjct: 72 ERTMIDPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLE------------------E 113
Query: 569 DLGAGNLEDFMKNSDNKALRRIFKK---CGRRVCAFNNKETGQAQETQVKALLTKVNDLR 625
DL D + L+++ +K C V E GQ Q+ Q +L V+DL
Sbjct: 114 DL-----------YDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQKLQT--VLEAVHDLL 160
Query: 626 KESGWS 631
+ GW+
Sbjct: 161 RPRGWA 166
>gi|239752326 PREDICTED: hypothetical protein [Homo sapiens]
Length = 77
Score = 30.4 bits (67), Expect = 5.5
Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 238 GPEQNPGTSELTVLLVGKRGAGKSAAGNSILGRQAFQTGFSEQSVTQSFLSESRSWRKKK 297
G + G+ E V G +GAG+S G+S++ + S S T LS S +W +KK
Sbjct: 6 GSREKNGSREEGV--AGVKGAGESGGGSSLM----CASWLSRVSRTGGLLSRSVAWTRKK 59
Query: 298 VS 299
S
Sbjct: 60 AS 61
>gi|239746837 PREDICTED: hypothetical protein XP_002344237 [Homo
sapiens]
Length = 77
Score = 30.4 bits (67), Expect = 5.5
Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 238 GPEQNPGTSELTVLLVGKRGAGKSAAGNSILGRQAFQTGFSEQSVTQSFLSESRSWRKKK 297
G + G+ E V G +GAG+S G+S++ + S S T LS S +W +KK
Sbjct: 6 GSREKNGSREEGV--AGVKGAGESGGGSSLM----CASWLSRVSRTGGLLSRSVAWTRKK 59
Query: 298 VS 299
S
Sbjct: 60 AS 61
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,109,187
Number of Sequences: 37866
Number of extensions: 1079501
Number of successful extensions: 3827
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 3705
Number of HSP's gapped (non-prelim): 100
length of query: 665
length of database: 18,247,518
effective HSP length: 109
effective length of query: 556
effective length of database: 14,120,124
effective search space: 7850788944
effective search space used: 7850788944
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.