Guide to the Human Genome
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Search of human proteins with 28376658

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28376658 hypothetical protein LOC285172 [Homo sapiens]
         (530 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28376658 hypothetical protein LOC285172 [Homo sapiens]            1044   0.0  
gi|19923646 family with sequence similarity 126, member A [Homo ...   509   e-144
gi|17402886 HEAT-like repeat-containing protein isoform 1 [Homo ...    38   0.020
gi|91982772 mucin 17 [Homo sapiens]                                    38   0.026
gi|219802034 nuclear factor related to kappaB binding protein is...    37   0.034
gi|23346420 nuclear factor related to kappaB binding protein iso...    37   0.034
gi|23308537 coiled-coil domain containing 140 [Homo sapiens]           37   0.045
gi|57864582 hornerin [Homo sapiens]                                    36   0.076
gi|61742814 coiled-coil and C2 domain containing 1B [Homo sapiens]     36   0.076
gi|55749544 SH3 multiple domains 1 [Homo sapiens]                      36   0.100
gi|71274144 AT hook, DNA binding motif, containing 1 [Homo sapiens]    35   0.13 
gi|38372909 jumonji domain containing 1B [Homo sapiens]                35   0.17 
gi|22035604 mitogen-activated protein kinase kinase kinase kinas...    35   0.17 
gi|33356174 pinin, desmosome associated protein [Homo sapiens]         34   0.29 
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        34   0.38 
gi|216548091 leucine zipper protein 1 [Homo sapiens]                   33   0.49 
gi|216548085 leucine zipper protein 1 [Homo sapiens]                   33   0.49 
gi|22035606 mitogen-activated protein kinase kinase kinase kinas...    33   0.49 
gi|22035602 mitogen-activated protein kinase kinase kinase kinas...    33   0.49 
gi|95147342 chromodomain helicase DNA binding protein 9 [Homo sa...    33   0.65 
gi|208431824 forkhead box I3 [Homo sapiens]                            33   0.84 
gi|21327710 nucleosome assembly protein 1-like 3 [Homo sapiens]        32   1.4  
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap...    32   1.4  
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap...    32   1.4  
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi...    32   1.4  
gi|169215453 PREDICTED: hypothetical protein [Homo sapiens]            32   1.9  
gi|169215350 PREDICTED: hypothetical protein [Homo sapiens]            32   1.9  
gi|146232000 checkpoint suppressor 1 isoform 1 [Homo sapiens]          32   1.9  
gi|51093865 checkpoint suppressor 1 isoform 2 [Homo sapiens]           32   1.9  
gi|110349786 Alstrom syndrome 1 [Homo sapiens]                         31   2.5  

>gi|28376658 hypothetical protein LOC285172 [Homo sapiens]
          Length = 530

 Score = 1044 bits (2700), Expect = 0.0
 Identities = 530/530 (100%), Positives = 530/530 (100%)

Query: 1   MLGTDRCVVEEWLSEFKALPDTQITSYAATLHRKKTLVPALYKVIQDSNNELLEPVCHQL 60
           MLGTDRCVVEEWLSEFKALPDTQITSYAATLHRKKTLVPALYKVIQDSNNELLEPVCHQL
Sbjct: 1   MLGTDRCVVEEWLSEFKALPDTQITSYAATLHRKKTLVPALYKVIQDSNNELLEPVCHQL 60

Query: 61  FELYRSSEVRLKRFTLQFLPELMWVYLRLTVSRDRQSNGCIEALLLGIYNLEIADKDGNN 120
           FELYRSSEVRLKRFTLQFLPELMWVYLRLTVSRDRQSNGCIEALLLGIYNLEIADKDGNN
Sbjct: 61  FELYRSSEVRLKRFTLQFLPELMWVYLRLTVSRDRQSNGCIEALLLGIYNLEIADKDGNN 120

Query: 121 KVLSFTIPSLSKPSIYHEPSTIGSMALTEGALCQHDLIRVVYSDLHPQRETFTAQNRFEV 180
           KVLSFTIPSLSKPSIYHEPSTIGSMALTEGALCQHDLIRVVYSDLHPQRETFTAQNRFEV
Sbjct: 121 KVLSFTIPSLSKPSIYHEPSTIGSMALTEGALCQHDLIRVVYSDLHPQRETFTAQNRFEV 180

Query: 181 LSFLMLCYNSAIVYMPASSYQSLCRMGSRVCVSGFPRQHEKHWKELCGRIVLDPEFMVQL 240
           LSFLMLCYNSAIVYMPASSYQSLCRMGSRVCVSGFPRQHEKHWKELCGRIVLDPEFMVQL
Sbjct: 181 LSFLMLCYNSAIVYMPASSYQSLCRMGSRVCVSGFPRQHEKHWKELCGRIVLDPEFMVQL 240

Query: 241 LTGVYYAMYNGQWDLGQEVLDDIIYRAQLELFSQPLLVANAMKNSLPFDAPDSTQEGQKV 300
           LTGVYYAMYNGQWDLGQEVLDDIIYRAQLELFSQPLLVANAMKNSLPFDAPDSTQEGQKV
Sbjct: 241 LTGVYYAMYNGQWDLGQEVLDDIIYRAQLELFSQPLLVANAMKNSLPFDAPDSTQEGQKV 300

Query: 301 LKVEVTPTVPRISRTAITTASIRRHRWRREGAEGVNGGEESVNLNDADEGFSSGASLSSQ 360
           LKVEVTPTVPRISRTAITTASIRRHRWRREGAEGVNGGEESVNLNDADEGFSSGASLSSQ
Sbjct: 301 LKVEVTPTVPRISRTAITTASIRRHRWRREGAEGVNGGEESVNLNDADEGFSSGASLSSQ 360

Query: 361 PIGTKPSSSSQRGSLRKVATGRSAKDKETASAIKSSESPRDSVVRKQYVQQPTDLSVDSV 420
           PIGTKPSSSSQRGSLRKVATGRSAKDKETASAIKSSESPRDSVVRKQYVQQPTDLSVDSV
Sbjct: 361 PIGTKPSSSSQRGSLRKVATGRSAKDKETASAIKSSESPRDSVVRKQYVQQPTDLSVDSV 420

Query: 421 ELTPMKKHLSLPAGQVVPKINSLSLIRTASASSSKSFDYVNGSQASTSIGVGTEGGTNLA 480
           ELTPMKKHLSLPAGQVVPKINSLSLIRTASASSSKSFDYVNGSQASTSIGVGTEGGTNLA
Sbjct: 421 ELTPMKKHLSLPAGQVVPKINSLSLIRTASASSSKSFDYVNGSQASTSIGVGTEGGTNLA 480

Query: 481 ANNANRYSTVSLQEDRLGQAGEGKELLSPGAPLTKQSRSPSFNMQLISQV 530
           ANNANRYSTVSLQEDRLGQAGEGKELLSPGAPLTKQSRSPSFNMQLISQV
Sbjct: 481 ANNANRYSTVSLQEDRLGQAGEGKELLSPGAPLTKQSRSPSFNMQLISQV 530


>gi|19923646 family with sequence similarity 126, member A [Homo
           sapiens]
          Length = 521

 Score =  509 bits (1312), Expect = e-144
 Identities = 278/537 (51%), Positives = 365/537 (67%), Gaps = 30/537 (5%)

Query: 1   MLGTDRCVVEEWLSEFKALPDTQITSYAATLHRKKTLVPALYKVIQDSNNELLEPVCHQL 60
           M  +++ VVEEWLSEFK LP+T + +YA  L  K +LV +LYKVIQ+  +ELLEPVCHQL
Sbjct: 1   MFTSEKGVVEEWLSEFKTLPETSLPNYATNLKDKSSLVSSLYKVIQEPQSELLEPVCHQL 60

Query: 61  FELYRSSEVRLKRFTLQFLPELMWVYLRLTVSRDRQSNGCIEALLLGIYNLEIADKDGNN 120
           FE YRS E +L +FTLQFLPEL+W YL ++ SR+  S+GCIEALLLG+YNLEI DK G+ 
Sbjct: 61  FEFYRSGEEQLLQFTLQFLPELIWCYLAVSASRNVHSSGCIEALLLGVYNLEIVDKQGHT 120

Query: 121 KVLSFTIPSLSKPSIYHEPSTIGSMALTEGALCQHDLIRVVYSDLHPQRETFTAQNRFEV 180
           KVLSFTIPSLSKPS+YHEPS+IGSMALTE AL QH L +VVYS  HPQRE  TAQNRFEV
Sbjct: 121 KVLSFTIPSLSKPSVYHEPSSIGSMALTESALSQHGLSKVVYSGPHPQREMLTAQNRFEV 180

Query: 181 LSFLMLCYNSAIVYMPASSYQSLCRMGSRVCVSGFPRQHEKHWKELCGRIVLDPEFMVQL 240
           L+FL+LCYN+A+ YMP+ S QSLC++ SR+CV G+PRQH + +K +  RI +   FMVQ+
Sbjct: 181 LTFLLLCYNAALTYMPSVSLQSLCQICSRICVCGYPRQHVRKYKGISSRIPVSSGFMVQM 240

Query: 241 LTGVYYAMYNGQWDLGQEVLDDIIYRAQLELFSQPLLVANAMKNSLPFDAPDSTQEGQKV 300
           LTG+Y+A YNG+WDL Q+ LDDIIYRAQLEL+ +PLLVANA+K SLP     S +EG + 
Sbjct: 241 LTGIYFAFYNGEWDLAQKALDDIIYRAQLELYPEPLLVANAIKASLPHGPMKSNKEGTRC 300

Query: 301 LKVEVTPTVPRISRTAITTASIRRHRWRREGAEGVNGGEESVNLNDADEGFSSGASLSSQ 360
           ++VE+TPT  RISR A+T+ SIR HRW+R G   + G EE + +++ DEGF S A+ S+ 
Sbjct: 301 IQVEITPTSSRISRNAVTSMSIRGHRWKRHGNTELTGQEELMEISEVDEGFYSRAASSTS 360

Query: 361 PIGTKPSS-------SSQRGSLRKVATGRSAKDKETASAIKSSESPRDSVVRKQYVQQPT 413
             G   SS       S  +   R   +    K+KET     + ES +D   RKQ  +  +
Sbjct: 361 QSGLSNSSHNCSNKPSIGKNHRRSGGSKTGGKEKET-----TGESCKDHFARKQTQRAQS 415

Query: 414 DLSVDSVELTPMKKHLSLPAGQVVPKINSLSLIRTASASSSKSFDYVNG----SQASTSI 469
               +++EL  +K+ L+L   Q +PK +S  L +TA+   SKSF+ V+G       S+++
Sbjct: 416 ----ENLELLSLKR-LTLTTSQSLPKPSSHGLAKTAATVFSKSFEQVSGVTVPHNPSSAV 470

Query: 470 GVGTEGGTNLAANNANRYSTVSLQEDRLGQAGEGKELLSPGAPLTKQSRSPSFNMQL 526
           G G       A  +ANR+S  SLQE++L    E  EL  P    + Q R PS ++ L
Sbjct: 471 GCG-------AGTDANRFSACSLQEEKLIYVSERTEL--PMKHQSGQQRPPSISITL 518


>gi|17402886 HEAT-like repeat-containing protein isoform 1 [Homo
           sapiens]
          Length = 873

 Score = 38.1 bits (87), Expect = 0.020
 Identities = 33/133 (24%), Positives = 60/133 (45%), Gaps = 9/133 (6%)

Query: 34  KKTLVPALYKVIQDSNNELLEPVCHQLFELYRSSEVRLKRFTLQFLPELMWVYLRLTVSR 93
           K+ ++P +  + QD   E+   +C QL  + +     L +  +  LPEL      + +SR
Sbjct: 210 KREILPLVKSLCQDVEYEVRSCMCRQLENIAQGIGTELTKSVV--LPEL------IELSR 261

Query: 94  DRQSNGCIEALLLGIYNLEIADKDGNNKVLSFTIPSLSKPSIYHEPSTIGSMALTEGALC 153
           D  S+  + A    +  L+I D D  ++ +   + S  + S   + S + S++   G LC
Sbjct: 262 DEGSSVRLAAFETLVNLLDIFDTDDRSQTILPLVKSFCEKSFKADESILISLSFHLGKLC 321

Query: 154 QHDLIRVVYSDLH 166
            H L  +   D H
Sbjct: 322 -HGLYGIFTPDQH 333


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 37.7 bits (86), Expect = 0.026
 Identities = 46/182 (25%), Positives = 79/182 (43%), Gaps = 22/182 (12%)

Query: 302 KVEVTPTVPRISRTAITTASIRRHRWRREGAEGVNGGEESVNLNDADEGFSSGASLSSQP 361
           +   T T+P  S+T +TTAS          +      + S+  +   EG      L+S P
Sbjct: 409 EASTTSTIPVDSKTFVTTAS-------EASSSPTTAEDTSIATSTPSEG---STPLTSMP 458

Query: 362 IGTKPSSSSQRGSLRKVATGRSAKDKETASAIKSSESPRDSVVRKQYVQQPTDLS--VDS 419
           + T P +SS+  +L    T   +K + T S  ++S SP  + V       P++ S  + S
Sbjct: 459 VSTTPVASSEASNLS--TTPVDSKTQVTTST-EASSSPPTAEVNSMPTSTPSEGSTPLTS 515

Query: 420 VELTPMKKHLSLPAGQVVPKINSLSLIRTASASSSKSFDYVNGSQASTSIGVGT--EGGT 477
           + ++ M    S  +      +++ + + T+S +SS S      +   TSI   T  EG T
Sbjct: 516 MSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSS-----TTPEGTSIPTSTPSEGST 570

Query: 478 NL 479
            L
Sbjct: 571 PL 572



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 28/132 (21%), Positives = 62/132 (46%), Gaps = 6/132 (4%)

Query: 351  FSSGAS-LSSQPIGTKPSSSSQRGSLRKVATGRSAKDKETASAIKSSESPRDSVVRKQYV 409
            +S G++ L S P+ TKP +SS+  +L       S       ++ ++S SP  +      +
Sbjct: 2569 YSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSI---PVTTSTETSSSPTTAKDTSMPI 2625

Query: 410  QQPTDL--SVDSVELTPMKKHLSLPAGQVVPKINSLSLIRTASASSSKSFDYVNGSQAST 467
              P+++  S+ S+ ++ M    S  +      +++ +L+ T++ +SS        S  ++
Sbjct: 2626 STPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTS 2685

Query: 468  SIGVGTEGGTNL 479
            + G  +   TN+
Sbjct: 2686 TPGERSTPLTNI 2697



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 33/139 (23%), Positives = 54/139 (38%), Gaps = 6/139 (4%)

Query: 357  LSSQPIGTKPSSSSQRGSLRKVATGRSAKDKETASAIKSSESPRDSVVRKQYVQQ-PTDL 415
            L+S P+ T P  SS+ G+L       S     +  A  S  +  D VV      +  T L
Sbjct: 2458 LASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLL 2517

Query: 416  SVDSVELTPMKKH-----LSLPAGQVVPKINSLSLIRTASASSSKSFDYVNGSQASTSIG 470
            +   V  TP+         + P     P + S  +  +A+++   S      S+ ST + 
Sbjct: 2518 TSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLR 2577

Query: 471  VGTEGGTNLAANNANRYST 489
                    LA++ A+  ST
Sbjct: 2578 SMPVSTKPLASSEASTLST 2596


>gi|219802034 nuclear factor related to kappaB binding protein isoform
            1 [Homo sapiens]
          Length = 1299

 Score = 37.4 bits (85), Expect = 0.034
 Identities = 58/251 (23%), Positives = 105/251 (41%), Gaps = 33/251 (13%)

Query: 256  GQEVLDDIIYRAQLELFSQ-----PLLVANAMKNS-----LPFDAPDSTQEGQKVLKVEV 305
            GQ ++  +    QL +  Q     PL   N          LP  +  +  +GQ VL++  
Sbjct: 915  GQNIIKQVAITGQLGVKPQTGNSIPLTATNFRIQGKDVLRLPPSSITTDAKGQTVLRI-- 972

Query: 306  TPTV-PRISRTAITTASIRRHRWRREG---AEGVNGG----EESVNLNDADEGFSSGASL 357
            TP +   ++++ +TT  + +  +   G    +G++         V+  D+    SS ++ 
Sbjct: 973  TPDMMATLAKSQVTTVKLTQDLFGTGGNTTGKGISATLHVTSNPVHAADSPAKASSASAP 1032

Query: 358  SSQPIGT---------KPSSSSQRGSLRKVATGRSAKDKETASAIKSSESPRDSVVR--K 406
            SS P GT         KP+ +S        A G S  D++  S + SSE+   + +R  +
Sbjct: 1033 SSTPTGTTVVKVTPDLKPTEASSSAFRLMPALGVSVADQKGKSTVASSEAKPAATIRIVQ 1092

Query: 407  QYVQQPTDLSVDSVELTPMKKHLSLPAGQVVPKINSLSLIRTASASSSKSFDYVNGSQAS 466
                 P          T  K+  S+ +G      +++SL  + +A+ SK+    +G+ AS
Sbjct: 1093 GLGVMPPKAGQTITVATHAKQGASVASGSGTVHTSAVSL-PSMNAAVSKTVAVASGA-AS 1150

Query: 467  TSIGVGTEGGT 477
            T I + T   T
Sbjct: 1151 TPISISTGAPT 1161


>gi|23346420 nuclear factor related to kappaB binding protein isoform
            2 [Homo sapiens]
          Length = 1324

 Score = 37.4 bits (85), Expect = 0.034
 Identities = 58/251 (23%), Positives = 105/251 (41%), Gaps = 33/251 (13%)

Query: 256  GQEVLDDIIYRAQLELFSQ-----PLLVANAMKNS-----LPFDAPDSTQEGQKVLKVEV 305
            GQ ++  +    QL +  Q     PL   N          LP  +  +  +GQ VL++  
Sbjct: 940  GQNIIKQVAITGQLGVKPQTGNSIPLTATNFRIQGKDVLRLPPSSITTDAKGQTVLRI-- 997

Query: 306  TPTV-PRISRTAITTASIRRHRWRREG---AEGVNGG----EESVNLNDADEGFSSGASL 357
            TP +   ++++ +TT  + +  +   G    +G++         V+  D+    SS ++ 
Sbjct: 998  TPDMMATLAKSQVTTVKLTQDLFGTGGNTTGKGISATLHVTSNPVHAADSPAKASSASAP 1057

Query: 358  SSQPIGT---------KPSSSSQRGSLRKVATGRSAKDKETASAIKSSESPRDSVVR--K 406
            SS P GT         KP+ +S        A G S  D++  S + SSE+   + +R  +
Sbjct: 1058 SSTPTGTTVVKVTPDLKPTEASSSAFRLMPALGVSVADQKGKSTVASSEAKPAATIRIVQ 1117

Query: 407  QYVQQPTDLSVDSVELTPMKKHLSLPAGQVVPKINSLSLIRTASASSSKSFDYVNGSQAS 466
                 P          T  K+  S+ +G      +++SL  + +A+ SK+    +G+ AS
Sbjct: 1118 GLGVMPPKAGQTITVATHAKQGASVASGSGTVHTSAVSL-PSMNAAVSKTVAVASGA-AS 1175

Query: 467  TSIGVGTEGGT 477
            T I + T   T
Sbjct: 1176 TPISISTGAPT 1186


>gi|23308537 coiled-coil domain containing 140 [Homo sapiens]
          Length = 163

 Score = 37.0 bits (84), Expect = 0.045
 Identities = 39/148 (26%), Positives = 60/148 (40%), Gaps = 18/148 (12%)

Query: 273 SQPLLVANAMKNSLPFDAPDSTQEGQKVLKVEVTPTVPRISR------TAITTASIRRHR 326
           S P L+A    +S P+D  +  QE       E    VPR+ +      TA  T   +R+R
Sbjct: 6   SNPDLLAEP-GSSPPWDHGNQRQEAAN----ESNTRVPRVLKAHLGPETAQPTKRSKRNR 60

Query: 327 WRREGAEGVNGGEESVNLNDADEGFSSGASLSSQPIGTKPSSSSQRG---SLRKVATGRS 383
           WRR+  +G +       L  AD G   G   S+        S+S R    S +    GR+
Sbjct: 61  WRRQSCQGPSPARSGQFLGSADLGLQRGVLKSAARTCLSEISNSTRASPESAQSTDPGRA 120

Query: 384 AKDK----ETASAIKSSESPRDSVVRKQ 407
           A+ +     T  + K  E   +   +K+
Sbjct: 121 ARPRTRTLPTPHSFKIGEEAEEMKKKKE 148


>gi|57864582 hornerin [Homo sapiens]
          Length = 2850

 Score = 36.2 bits (82), Expect = 0.076
 Identities = 45/180 (25%), Positives = 63/180 (35%), Gaps = 7/180 (3%)

Query: 325  HRWRREGAEGVNGGEESVNLNDADEGFSSGASLSSQPIGTKPSSSSQRGSLRKVATGRSA 384
            HR  R G     G   S + + +  G    AS  S   G   +SS Q  S  +  +G S 
Sbjct: 1992 HRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQ 2051

Query: 385  KDKETASAIKSSESPRDSVVRKQYVQQPTDLSVDSVELTPMKKHLSLPAGQVVPKINSLS 444
                      S +SP          Q P      S          S  +GQ  P +   S
Sbjct: 2052 SSGYGRQGSGSGQSPGHGQRGSGSRQSP------SYGRHGSGSGRSSSSGQHGPGLGESS 2105

Query: 445  LIRTASASSSKSFDYV-NGSQASTSIGVGTEGGTNLAANNANRYSTVSLQEDRLGQAGEG 503
                  +SS +S  Y  +GS +  S G G  G  +  ++   R+ + S    R GQ G G
Sbjct: 2106 GFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSG 2165



 Score = 32.7 bits (73), Expect = 0.84
 Identities = 47/199 (23%), Positives = 69/199 (34%), Gaps = 8/199 (4%)

Query: 325  HRWRREGAEGVNGGEESVNLNDADEGFSSGASLSSQPIGTKPSSSSQRGSLRKVATGRSA 384
            HR  R G     G   S + + +  G     S  S   G   +SS Q  S  +  +G S 
Sbjct: 1522 HRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQ 1581

Query: 385  KDKETASAIKSSESPRDSVVRKQYVQQPTDLSVDSVELTPMKKHLSLPAGQVVPKINSLS 444
                      S +SP          Q P      S          S  +GQ    +   S
Sbjct: 1582 SSGYGRQGSGSGQSPGHGQRGSGSRQSP------SYGRHGSGSGRSSSSGQHGSGLGESS 1635

Query: 445  LIRTASASSSKSFDYV-NGSQASTSIGVGTEGGTNLAANNANRYSTVSLQEDRLGQAGEG 503
                  +SS +S  Y  +GS +  S G G  G  +  ++   R+ + S    R GQ G G
Sbjct: 1636 GFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSG 1695

Query: 504  -KELLSPGAPLTKQSRSPS 521
             ++    G   +   +SPS
Sbjct: 1696 SRQSSGHGRQGSGSGQSPS 1714



 Score = 30.0 bits (66), Expect = 5.5
 Identities = 46/199 (23%), Positives = 68/199 (34%), Gaps = 8/199 (4%)

Query: 325  HRWRREGAEGVNGGEESVNLNDADEGFSSGASLSSQPIGTKPSSSSQRGSLRKVATGRSA 384
            HR  R G     G   S + + +  G     S  S   G   +SS Q  S  +  +G S 
Sbjct: 2462 HRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQ 2521

Query: 385  KDKETASAIKSSESPRDSVVRKQYVQQPTDLSVDSVELTPMKKHLSLPAGQVVPKINSLS 444
                      S +SP          Q P      S          S  +GQ    +   S
Sbjct: 2522 SSGYGRQGSGSGQSPGHGQRGSGSRQSP------SYGRHGSGSGRSSSSGQHGSGLGESS 2575

Query: 445  LIRTASASSSKSFDYV-NGSQASTSIGVGTEGGTNLAANNANRYSTVSLQEDRLGQAGEG 503
                  +SS +S  Y  +GS +  S G G  G  +  ++   R+ + S      GQ G G
Sbjct: 2576 GFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSG 2635

Query: 504  -KELLSPGAPLTKQSRSPS 521
             ++    G   +   +SPS
Sbjct: 2636 SRQSSGHGRQGSGSGQSPS 2654



 Score = 29.6 bits (65), Expect = 7.1
 Identities = 42/180 (23%), Positives = 60/180 (33%), Gaps = 7/180 (3%)

Query: 325  HRWRREGAEGVNGGEESVNLNDADEGFSSGASLSSQPIGTKPSSSSQRGSLRKVATGRSA 384
            HR  R G     G   S + + +  G     S  S   G   +SS Q  S  +  +G S 
Sbjct: 1052 HRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQ 1111

Query: 385  KDKETASAIKSSESPRDSVVRKQYVQQPTDLSVDSVELTPMKKHLSLPAGQVVPKINSLS 444
                      S +SP          Q P      S          S  +GQ    +   S
Sbjct: 1112 SSGYGRQGSGSGQSPGHGQRGSGSRQSP------SYGRHGSGSGRSSSSGQHGSGLGESS 1165

Query: 445  LIRTASASSSKSFDYV-NGSQASTSIGVGTEGGTNLAANNANRYSTVSLQEDRLGQAGEG 503
                  +SS +S  Y  +GS +  S G G  G  +  ++   R+ + S      GQ G G
Sbjct: 1166 GFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSG 1225



 Score = 29.3 bits (64), Expect = 9.3
 Identities = 40/161 (24%), Positives = 60/161 (37%), Gaps = 7/161 (4%)

Query: 350 GFSSGASLSSQPIGTKPSSSS---QRGSLRKVATGRSAKDKETASAIKSSESPRDSVVRK 406
           G  SG S   +  G+   SSS   Q GS  + + G S     +  +   S    +S  R+
Sbjct: 495 GSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQ 554

Query: 407 QYVQQPTDL-SVDSVELTPMKK---HLSLPAGQVVPKINSLSLIRTASASSSKSFDYVNG 462
                P    S  S    P +    H S    Q      S    +  S+S   S    +G
Sbjct: 555 SSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHG 614

Query: 463 SQASTSIGVGTEGGTNLAANNANRYSTVSLQEDRLGQAGEG 503
           S +  S   G  G T+  +++  ++ + S Q  R GQ G G
Sbjct: 615 STSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSG 655


>gi|61742814 coiled-coil and C2 domain containing 1B [Homo sapiens]
          Length = 858

 Score = 36.2 bits (82), Expect = 0.076
 Identities = 41/191 (21%), Positives = 68/191 (35%), Gaps = 22/191 (11%)

Query: 275 PLLVANAMKNSLPFDAPDSTQEGQKVLKVEVTPTVPRISRTAITTASIRRHRWRREGAEG 334
           P ++  A++   P  APD          V  TP  P  S+T +     R +++R  G + 
Sbjct: 353 PSVIPPAVERVQPVMAPD----------VPATPVAPTESQTVLDALQQRLNKYREAGIQA 402

Query: 335 VNGGEE---------SVNLNDADEGFSSGASLSSQPIGTKPSSSSQRGSLRKVATGRSAK 385
            +GG+E         +    DA     +G  ++   +   P      G    +     A 
Sbjct: 403 RSGGDERKARMHERIAKQYQDAIRAHRAGRKVNFAELPVPPGFPPIPGLESTMGVEEDAV 462

Query: 386 DKETASAIKSSESPRDSVVRKQYVQQPTDLSVDSVELTPMKKHLSLPAGQVVPKINSLSL 445
               A+A K + +   +   K   + P  L  +     P+ K    PA   VP    L  
Sbjct: 463 AATLAAAEKLASAEDSAPADKDEDEPPGHLQGEPPAQAPVAKK---PARPTVPSSQRLPE 519

Query: 446 IRTASASSSKS 456
            R +S+  S S
Sbjct: 520 PRASSSKESPS 530


>gi|55749544 SH3 multiple domains 1 [Homo sapiens]
          Length = 1105

 Score = 35.8 bits (81), Expect = 0.100
 Identities = 24/96 (25%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 341 SVNLNDADEGFSSGASLSSQPIGTKPSSSSQRGSLRKVATGRSAKDKETASAIKSSESPR 400
           ++N        SS +SLS      KP S+S  G +R     R+ KD +  + + S    +
Sbjct: 667 TINTTCCSSSSSSSSSLSKTSGDLKPRSASDAG-IRGTPKVRAKKDADANAGLTSCPRAK 725

Query: 401 DSVVRKQYVQQPTDLSVDSVELTPMKKHLSLPAGQV 436
            SV  K ++ +    S + ++++ +++ L  P GQ+
Sbjct: 726 PSVRPKPFLNRAESQSQEKMDISTLRRQLR-PTGQL 760


>gi|71274144 AT hook, DNA binding motif, containing 1 [Homo sapiens]
          Length = 1603

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 36/122 (29%), Positives = 45/122 (36%), Gaps = 18/122 (14%)

Query: 338  GEESVNLNDADEGFSSGASLSSQPIGTKPSSSSQRGSLRKVATGRSAKDKETASAIKSSE 397
            G++  N  D    + SG SL + P      SS+         TG        AS   SSE
Sbjct: 989  GQDCANSKDCSFAYGSGNSLPASP------SSAHSAGYAPPPTGGPCLPPSKASFFSSSE 1042

Query: 398  SPRDSVVRKQYVQQPTDLSVDSVELTPMKKHLSLPAGQVVPKINSLSLIRTASASSSKSF 457
                S         PT L  DS   T        P G +VPK  + S    ASA+SS S 
Sbjct: 1043 GAPFSG------SAPTPLRCDSRASTVS------PGGYMVPKGTTASATSAASAASSSSS 1090

Query: 458  DY 459
             +
Sbjct: 1091 SF 1092


>gi|38372909 jumonji domain containing 1B [Homo sapiens]
          Length = 1761

 Score = 35.0 bits (79), Expect = 0.17
 Identities = 53/225 (23%), Positives = 83/225 (36%), Gaps = 31/225 (13%)

Query: 306 TPTVPRISRTAITTASIRRHRWRREGAEGVNGGEESVNLNDADEGFSSGASLSSQPIGTK 365
           TP   RIS T +   ++     +++G+     GE S N   A  GF +    SSQP+   
Sbjct: 430 TPNTVRISDTGLAAGTVPE---KQKGSRSQASGENSRNSILASSGFGAPLPSSSQPLTFG 486

Query: 366 PSSSSQRGSLRKVATGRSAKDKETASAIKSSESPRDSVVRKQYVQQPTDLSVDSVELTPM 425
              S   G L       + ++K    +   S +        Q  Q+ TDLS         
Sbjct: 487 SGRSQSNGVL-------ATENKPLGFSFGCSSA--------QEAQKDTDLS--------- 522

Query: 426 KKHLSLPAGQVVPKINSLSLIRTASASSSKSFDYVNGSQASTSIGVGTEGGTNLAANNAN 485
           K        Q +P  N  + +  + A  S S D  +  Q+  S+  G   G ++   +  
Sbjct: 523 KNLFFQCMSQTLPTSNYFTTVSESLADDSSSRD--SFKQSLESLSSGLCKGRSVLGTDTK 580

Query: 486 RYSTVSLQEDRLGQAGEGKELLSPGAPLT-KQSRSPSFNMQLISQ 529
             S      DR   A E    L+P  P +   +R+P  +  L  Q
Sbjct: 581 PGSKAGSSVDRKVPA-ESMPTLTPAFPRSLLNARTPENHENLFLQ 624


>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 2 [Homo sapiens]
          Length = 1320

 Score = 35.0 bits (79), Expect = 0.17
 Identities = 58/259 (22%), Positives = 100/259 (38%), Gaps = 30/259 (11%)

Query: 289 DAPDSTQEG-QKVLKVEVTPTVPRISRTAITTASIRRHRWRREGAEGVNGGEESVNLN-- 345
           +APD TQ+   +    EV P VP  + +     S R    +  G +    G+ +   +  
Sbjct: 679 EAPDPTQKAWSRSDSDEVPPRVPVRTTSRSPVLSRRDSPLQGSGQQNSQAGQRNSTSSIE 738

Query: 346 -------------DADEGFSSGASLSSQPIGTKPSSSSQRGSLRKVATGRSAKDKETASA 392
                            G SSG+S S    G+ P S S  G   +V +   ++   +   
Sbjct: 739 PRLLWERVEKLVPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKSEGSPSQRL 798

Query: 393 IKSSESPRDSVVRKQYVQQPTDLSVDSVELTPMKKHLSLPAGQVVP-KINSLSLIRTASA 451
             + + P D    K+ V +P       V+LT + K L        P K+   S     S 
Sbjct: 799 ENAVKKPED----KKEVFRPLK-PAGEVDLTALAKELRAVEDVRPPHKVTDYSSSSEESG 853

Query: 452 SSSKSFDYV--NGSQASTSIGVGTEGGTNLAANNANRYSTVSLQEDRLGQAGEGKELLSP 509
           ++ +  D V   G+  STS    T   ++L  +N     T S++   +    E +  ++P
Sbjct: 854 TTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNG---ETESVKTMIVHDDVESEPAMTP 910

Query: 510 ---GAPLTKQSRSPSFNMQ 525
              G  + +Q++S S  +Q
Sbjct: 911 SKEGTLIVRQTQSASSTLQ 929


>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
          Length = 717

 Score = 34.3 bits (77), Expect = 0.29
 Identities = 33/109 (30%), Positives = 53/109 (48%), Gaps = 8/109 (7%)

Query: 292 DSTQEGQKVLKVEVTP--TVPRISRTAITTASIRRHRWRREGAEGVNGGEESVNLNDADE 349
           D   E  K+ +V V P  TV   S++   T S  R R R + ++  +    S + + +  
Sbjct: 529 DFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSST 588

Query: 350 GFSSGASLSSQPIGTKPSSSSQRGSLRKVATGRSAKDKETASAIKSSES 398
             SSG+S SS    ++ SSSS   +     +G S++D  ++S   SSES
Sbjct: 589 SSSSGSSSSSGSSSSRSSSSSSSST-----SGSSSRD-SSSSTSSSSES 631


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 33.9 bits (76), Expect = 0.38
 Identities = 49/195 (25%), Positives = 80/195 (41%), Gaps = 19/195 (9%)

Query: 291  PDSTQEGQKVLKVEVTPTVPRISRT----AITTASIRRHRWRRE-GAEGVNGGEESVNLN 345
            P +  +  + L  + TP     S +    A TT+S   H       A GV   +  V   
Sbjct: 2452 PSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSD--VGEP 2509

Query: 346  DADEGFSSGASLSS-QPIGTKPSSSSQRGSLRKVATGRSAKDKETASAIKSSESPRDSV- 403
             A  G    ++L++ QP   + SSSS   S    ++  S+    ++S   SS+S   S+ 
Sbjct: 2510 PASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLP 2569

Query: 404  ----VRKQYVQQPTDLSVDSV------ELTPMKKHLSLPAGQVVPKINSLSLIRTASASS 453
                V  + V  PT    ++V      E TP K+     +       +S S   ++S+SS
Sbjct: 2570 VQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSS 2629

Query: 454  SKSFDYVNGSQASTS 468
            S S    + S +S+S
Sbjct: 2630 SSSSSSSSSSSSSSS 2644


>gi|216548091 leucine zipper protein 1 [Homo sapiens]
          Length = 1076

 Score = 33.5 bits (75), Expect = 0.49
 Identities = 32/140 (22%), Positives = 58/140 (41%), Gaps = 13/140 (9%)

Query: 328 RREGAEGVNGGEESVNLNDADEGF--SSGASLSSQPIGTKPSSSSQRGSLRKVATGRSAK 385
           RR  +EG++ G+++ N  +AD     S    LS  P     S  SQ   L+  +T     
Sbjct: 571 RRSSSEGLSKGKKAANGLEADNSCPNSKAPVLSKYPY----SCRSQENILQGFSTSHKEG 626

Query: 386 DKETASAIKSSESPRDS----VVRKQYVQQP---TDLSVDSVELTPMKKHLSLPAGQVVP 438
             + A+ +    SP ++    V++    ++P    DL + S+    +      P  +  P
Sbjct: 627 VNQPAAVVMEDSSPHEALRCRVIKSSGREKPDSDDDLDIASLVTAKLVNTTITPEPEPKP 686

Query: 439 KINSLSLIRTASASSSKSFD 458
           + NS    +T  A  +  F+
Sbjct: 687 QPNSREKAKTRGAPRTSLFE 706


>gi|216548085 leucine zipper protein 1 [Homo sapiens]
          Length = 1076

 Score = 33.5 bits (75), Expect = 0.49
 Identities = 32/140 (22%), Positives = 58/140 (41%), Gaps = 13/140 (9%)

Query: 328 RREGAEGVNGGEESVNLNDADEGF--SSGASLSSQPIGTKPSSSSQRGSLRKVATGRSAK 385
           RR  +EG++ G+++ N  +AD     S    LS  P     S  SQ   L+  +T     
Sbjct: 571 RRSSSEGLSKGKKAANGLEADNSCPNSKAPVLSKYPY----SCRSQENILQGFSTSHKEG 626

Query: 386 DKETASAIKSSESPRDS----VVRKQYVQQP---TDLSVDSVELTPMKKHLSLPAGQVVP 438
             + A+ +    SP ++    V++    ++P    DL + S+    +      P  +  P
Sbjct: 627 VNQPAAVVMEDSSPHEALRCRVIKSSGREKPDSDDDLDIASLVTAKLVNTTITPEPEPKP 686

Query: 439 KINSLSLIRTASASSSKSFD 458
           + NS    +T  A  +  F+
Sbjct: 687 QPNSREKAKTRGAPRTSLFE 706


>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 3 [Homo sapiens]
          Length = 1212

 Score = 33.5 bits (75), Expect = 0.49
 Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 14/182 (7%)

Query: 350 GFSSGASLSSQPIGTKPSSSSQRGSLRKVATGRSAKDKETASAIKSSESPRDSVVRKQYV 409
           G SSG+S S    G+ P S S  G   +V +   ++   +     + + P D    K+ V
Sbjct: 648 GSSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPED----KKEV 703

Query: 410 QQPTDLSVDSVELTPMKKHLSLPAGQVVP-KINSLSLIRTASASSSKSFDYV--NGSQAS 466
            +P       V+LT + K L        P K+   S     S ++ +  D V   G+  S
Sbjct: 704 FRPLK-PAGEVDLTALAKELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADES 762

Query: 467 TSIGVGTEGGTNLAANNANRYSTVSLQEDRLGQAGEGKELLSP---GAPLTKQSRSPSFN 523
           TS    T   ++L  +N     T S++   +    E +  ++P   G  + +Q++S S  
Sbjct: 763 TSGPEDTRAASSLNLSNG---ETESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASST 819

Query: 524 MQ 525
           +Q
Sbjct: 820 LQ 821


>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 1 [Homo sapiens]
          Length = 1166

 Score = 33.5 bits (75), Expect = 0.49
 Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 14/182 (7%)

Query: 350 GFSSGASLSSQPIGTKPSSSSQRGSLRKVATGRSAKDKETASAIKSSESPRDSVVRKQYV 409
           G SSG+S S    G+ P S S  G   +V +   ++   +     + + P D    K+ V
Sbjct: 594 GSSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPED----KKEV 649

Query: 410 QQPTDLSVDSVELTPMKKHLSLPAGQVVP-KINSLSLIRTASASSSKSFDYV--NGSQAS 466
            +P       V+LT + K L        P K+   S     S ++ +  D V   G+  S
Sbjct: 650 FRPLK-PAGEVDLTALAKELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADES 708

Query: 467 TSIGVGTEGGTNLAANNANRYSTVSLQEDRLGQAGEGKELLSP---GAPLTKQSRSPSFN 523
           TS    T   ++L  +N     T S++   +    E +  ++P   G  + +Q++S S  
Sbjct: 709 TSGPEDTRAASSLNLSNG---ETESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASST 765

Query: 524 MQ 525
           +Q
Sbjct: 766 LQ 767


>gi|95147342 chromodomain helicase DNA binding protein 9 [Homo
            sapiens]
          Length = 2881

 Score = 33.1 bits (74), Expect = 0.65
 Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 15/145 (10%)

Query: 338  GEESVNLNDADEGFSSGASLSSQPIGTKPSSSSQRGSLRKVATGRSAKDKETASAIKSSE 397
            G ES + +D+D   SS +S SS    +   S S+ GS    ++  S+    ++S+  SS 
Sbjct: 2127 GSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSSSS 2186

Query: 398  SPRDSVVRKQYVQQPTDLSVDSVELTPMKKHLSLPAGQVVPKINSLSLIRTASASSSKSF 457
            S   S        + +D   +  +      H+     +      S++ + T    +  SF
Sbjct: 2187 SSSSS------SSEESDSDEEEAQKRESTTHMKAYDEE------SVASLSTTQDETQDSF 2234

Query: 458  DYVNGSQASTSIGVGTEGGTNLAAN 482
               NG+  S  I    +GG  LAA+
Sbjct: 2235 QMNNGTPESAYI---LQGGYMLAAS 2256


>gi|208431824 forkhead box I3 [Homo sapiens]
          Length = 420

 Score = 32.7 bits (73), Expect = 0.84
 Identities = 38/166 (22%), Positives = 63/166 (37%), Gaps = 21/166 (12%)

Query: 321 SIRRHRWRREGAEGVNGGEESVNLNDADEGFSSGASLSSQPIGTKPSSSSQRGSLRKVAT 380
           + RR R RR  +E  NG   +   + ++EG SSG       +G KP   S    LR   +
Sbjct: 233 NFRRKRKRR--SEASNGSTVAAGTSKSEEGLSSGL---GSGVGGKPEEESPSTLLRPSHS 287

Query: 381 GRSAKDKETASAIKSSESPRDSVVRKQYVQQPTDLSVDSVELT----PMKKHLSLPAGQV 436
               +  ++ ++         +     +    + LSV S   T    P  +HL +   Q+
Sbjct: 288 PEPPEGTKSTASSPGGPMLTSTPCLNTFFSSLSSLSVSSSVSTQRALPGSRHLGIQGAQL 347

Query: 437 ------------VPKINSLSLIRTASASSSKSFDYVNGSQASTSIG 470
                           ++L L  + S S+ +   Y +   ASTS G
Sbjct: 348 PSSGVFSPTSISEASADTLQLSNSTSNSTGQRSSYYSPFPASTSGG 393


>gi|21327710 nucleosome assembly protein 1-like 3 [Homo sapiens]
          Length = 506

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 20/67 (29%), Positives = 33/67 (49%)

Query: 347 ADEGFSSGASLSSQPIGTKPSSSSQRGSLRKVATGRSAKDKETASAIKSSESPRDSVVRK 406
           A+E  +S  S S +   +  SSSS   S    +T  S+    ++S+   S S R  + RK
Sbjct: 18  AEEEMASSTSDSGEESDSSSSSSSTSDSSSSSSTSGSSSGSGSSSSSSGSTSSRSRLYRK 77

Query: 407 QYVQQPT 413
           + V +P+
Sbjct: 78  KRVPEPS 84


>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
           sapiens]
          Length = 1293

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 10/119 (8%)

Query: 323 RRHRWRREGAEGVNGGEESVN---LNDADEGF----SSGASLSSQPIGTKPSSSSQRGSL 375
           R +R  R G+  ++   +S+    L DA+E      SSGA LS + +  +P    Q    
Sbjct: 260 RGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDF 319

Query: 376 RKVATGRSAKDKETASAIKSSESPRDSVVRKQYVQQPTDLSVDSVELTPMKKHLSLPAG 434
           R V  G    D E +    + E+       K+  ++   + V++ E TP     S   G
Sbjct: 320 RPVDEGEECSDSEGS---HNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPG 375


>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
           sapiens]
          Length = 1299

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 10/119 (8%)

Query: 323 RRHRWRREGAEGVNGGEESVN---LNDADEGF----SSGASLSSQPIGTKPSSSSQRGSL 375
           R +R  R G+  ++   +S+    L DA+E      SSGA LS + +  +P    Q    
Sbjct: 266 RGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDF 325

Query: 376 RKVATGRSAKDKETASAIKSSESPRDSVVRKQYVQQPTDLSVDSVELTPMKKHLSLPAG 434
           R V  G    D E +    + E+       K+  ++   + V++ E TP     S   G
Sbjct: 326 RPVDEGEECSDSEGS---HNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPG 381


>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
           sapiens]
          Length = 1299

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 10/119 (8%)

Query: 323 RRHRWRREGAEGVNGGEESVN---LNDADEGF----SSGASLSSQPIGTKPSSSSQRGSL 375
           R +R  R G+  ++   +S+    L DA+E      SSGA LS + +  +P    Q    
Sbjct: 266 RGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDF 325

Query: 376 RKVATGRSAKDKETASAIKSSESPRDSVVRKQYVQQPTDLSVDSVELTPMKKHLSLPAG 434
           R V  G    D E +    + E+       K+  ++   + V++ E TP     S   G
Sbjct: 326 RPVDEGEECSDSEGS---HNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPG 381


>gi|169215453 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 707

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 15/131 (11%)

Query: 279 ANAMKNSLPFDAPD--STQEGQKVLKVEVTPTVPRISRTAI-TTASIRRHRWRREGAEGV 335
           A ++  SL +  PD  ST++  +VLK  V PTV R+ ++ +  TAS+            +
Sbjct: 195 AFSVARSLSWKVPDHKSTRKVSRVLKGGVDPTVSRVLKSGVDPTASL------------L 242

Query: 336 NGGEESVNLNDADEGFSSGASLSSQPIGTKPSSSSQRGSLRKVATGRSAKDKETASAIKS 395
            GG +         G    ASL    +    S   + G     +  R      TAS +K 
Sbjct: 243 KGGVDPTASRVRKGGVDPTASLLKGGVDPTASRVRKGGVDPTASCVRKGGVDPTASLLKG 302

Query: 396 SESPRDSVVRK 406
              P  S VRK
Sbjct: 303 GVDPTVSHVRK 313


>gi|169215350 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 707

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 15/131 (11%)

Query: 279 ANAMKNSLPFDAPD--STQEGQKVLKVEVTPTVPRISRTAI-TTASIRRHRWRREGAEGV 335
           A ++  SL +  PD  ST++  +VLK  V PTV R+ ++ +  TAS+            +
Sbjct: 195 AFSVARSLSWKVPDHKSTRKVSRVLKGGVDPTVSRVLKSGVDPTASL------------L 242

Query: 336 NGGEESVNLNDADEGFSSGASLSSQPIGTKPSSSSQRGSLRKVATGRSAKDKETASAIKS 395
            GG +         G    ASL    +    S   + G     +  R      TAS +K 
Sbjct: 243 KGGVDPTASRVRKGGVDPTASLLKGGVDPTASRVRKGGVDPTASRVRKGGVDPTASLLKG 302

Query: 396 SESPRDSVVRK 406
              P  S VRK
Sbjct: 303 GVDPTVSHVRK 313


>gi|146232000 checkpoint suppressor 1 isoform 1 [Homo sapiens]
          Length = 490

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 44/162 (27%), Positives = 65/162 (40%), Gaps = 17/162 (10%)

Query: 291 PDSTQEGQKVLK---------VEVTPT-VPRISRTAITTASIRRHRWRREGAEGVNGG-E 339
           P   Q G +VL          + +TP  V    R  IT+  +R       G+  V+G  +
Sbjct: 273 PGVIQNGARVLSRGLFPGVRPLPITPIGVTAAMRNGITSCRMRTESEPSCGSPVVSGDPK 332

Query: 340 ESVNLNDADEGFSSGASLSSQPIGTKPSSSSQRGSLRKVATGRSAKDKE-TASAIKSSES 398
           E  N + A    +   S +S  I    SSSS      + AT  S +  E +  + +S ES
Sbjct: 333 EDHNYSSAKSSNARSTSPTSDSIS---SSSSSADDHYEFATKGSQEGSEGSEGSFRSHES 389

Query: 399 PRDSVV--RKQYVQQPTDLSVDSVELTPMKKHLSLPAGQVVP 438
           P D+    RK   ++P D   DS   +  KK       + VP
Sbjct: 390 PSDTEEDDRKHSQKEPKDSLGDSGYASQHKKRQHFAKARKVP 431


>gi|51093865 checkpoint suppressor 1 isoform 2 [Homo sapiens]
          Length = 468

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 44/162 (27%), Positives = 65/162 (40%), Gaps = 17/162 (10%)

Query: 291 PDSTQEGQKVLK---------VEVTPT-VPRISRTAITTASIRRHRWRREGAEGVNGG-E 339
           P   Q G +VL          + +TP  V    R  IT+  +R       G+  V+G  +
Sbjct: 251 PGVIQNGARVLSRGLFPGVRPLPITPIGVTAAMRNGITSCRMRTESEPSCGSPVVSGDPK 310

Query: 340 ESVNLNDADEGFSSGASLSSQPIGTKPSSSSQRGSLRKVATGRSAKDKE-TASAIKSSES 398
           E  N + A    +   S +S  I    SSSS      + AT  S +  E +  + +S ES
Sbjct: 311 EDHNYSSAKSSNARSTSPTSDSIS---SSSSSADDHYEFATKGSQEGSEGSEGSFRSHES 367

Query: 399 PRDSVV--RKQYVQQPTDLSVDSVELTPMKKHLSLPAGQVVP 438
           P D+    RK   ++P D   DS   +  KK       + VP
Sbjct: 368 PSDTEEDDRKHSQKEPKDSLGDSGYASQHKKRQHFAKARKVP 409


>gi|110349786 Alstrom syndrome 1 [Homo sapiens]
          Length = 4169

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 20/61 (32%), Positives = 29/61 (47%), Gaps = 1/61 (1%)

Query: 15   EFKALPDTQITSYAATLHRKKTLVPALYKVIQDS-NNELLEPVCHQLFELYRSSEVRLKR 73
            E K LPDT+  +    +HRKKT+    +   ++S    + E  CH  FE    S  R  +
Sbjct: 3423 EMKNLPDTKAITQKEEIHRKKTVPEEAWPNNKESLQINIEESECHSEFENTTRSVFRSAK 3482

Query: 74   F 74
            F
Sbjct: 3483 F 3483


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.130    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,047,010
Number of Sequences: 37866
Number of extensions: 821488
Number of successful extensions: 3021
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 2944
Number of HSP's gapped (non-prelim): 108
length of query: 530
length of database: 18,247,518
effective HSP length: 107
effective length of query: 423
effective length of database: 14,195,856
effective search space: 6004847088
effective search space used: 6004847088
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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