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Search of human proteins with 28173558
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28173558 trace amine associated receptor 6 [Homo sapiens]
(345 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28173558 trace amine associated receptor 6 [Homo sapiens] 703 0.0
gi|16751917 trace amine associated receptor 8 [Homo sapiens] 566 e-161
gi|110618256 trace amine associated receptor 9 [Homo sapiens] 510 e-145
gi|223633986 trace amine associated receptor 5 [Homo sapiens] 304 7e-83
gi|21264324 trace amine associated receptor 1 [Homo sapiens] 278 4e-75
gi|74275344 trace amine associated receptor 2 isoform 1 [Homo sa... 264 8e-71
gi|74275342 trace amine associated receptor 2 isoform 2 [Homo sa... 255 4e-68
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens] 178 6e-45
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens] 178 6e-45
gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens] 178 6e-45
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens] 178 6e-45
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens] 178 6e-45
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens] 178 6e-45
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens] 178 6e-45
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens] 166 4e-41
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens] 166 4e-41
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens] 166 4e-41
gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens] 166 4e-41
gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens] 158 6e-39
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens] 154 9e-38
gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens] 154 9e-38
gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo sap... 152 4e-37
gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo sap... 151 9e-37
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] 151 9e-37
gi|4503383 dopamine receptor D1 [Homo sapiens] 144 9e-35
gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens] 144 2e-34
gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens] 144 2e-34
gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens] 144 2e-34
gi|10835197 5-hydroxytryptamine (serotonin) receptor 1F [Homo sa... 141 7e-34
gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapi... 135 7e-32
>gi|28173558 trace amine associated receptor 6 [Homo sapiens]
Length = 345
Score = 703 bits (1814), Expect = 0.0
Identities = 345/345 (100%), Positives = 345/345 (100%)
Query: 1 MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHF 60
MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHF
Sbjct: 1 MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHF 60
Query: 61 KQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSL 120
KQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSL
Sbjct: 61 KQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSL 120
Query: 121 FHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEEL 180
FHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEEL
Sbjct: 121 FHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEEL 180
Query: 181 SDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTES 240
SDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTES
Sbjct: 181 SDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTES 240
Query: 241 SSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCA 300
SSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCA
Sbjct: 241 SSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCA 300
Query: 301 YYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI 345
YYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI
Sbjct: 301 YYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI 345
>gi|16751917 trace amine associated receptor 8 [Homo sapiens]
Length = 342
Score = 566 bits (1458), Expect = e-161
Identities = 273/343 (79%), Positives = 303/343 (88%), Gaps = 1/343 (0%)
Query: 1 MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHF 60
M+SN S V VQLCY +VNGSC++ P+SPGSRVILY F FG++LAVFGNLLVM S+LHF
Sbjct: 1 MTSNFSQPV-VQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHF 59
Query: 61 KQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSL 120
KQLHSPTNFL+ASLACADFLVGVTVM FSMVRTVESCWYFG FCT H+CCDVAFCYSS+
Sbjct: 60 KQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSV 119
Query: 121 FHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEEL 180
HLCFI IDRYI VTDPLVY TKFTVSVSGICISVSWILPL YSGAVFYTGV DDGLEEL
Sbjct: 120 LHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEEL 179
Query: 181 SDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTES 240
ALNC+GGCQ +V+Q WVL DFL FFIPT +MIILY IFL+A++QA KIE T SK ES
Sbjct: 180 VSALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVES 239
Query: 241 SSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCA 300
SSESYK RVA+RERKAAKTLGVTV+AF+ISWLPY++D LIDAFMGF+TPA IYEICCW A
Sbjct: 240 SSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSA 299
Query: 301 YYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSE 343
YYNSAMNPLIYALFYPWFRKAIK+I++G VLK SS+T++LF E
Sbjct: 300 YYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE 342
>gi|110618256 trace amine associated receptor 9 [Homo sapiens]
Length = 348
Score = 510 bits (1314), Expect = e-145
Identities = 238/345 (68%), Positives = 283/345 (82%)
Query: 1 MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHF 60
M +N S AV+LCY NVN SC+K P+SPG R ILY V GFGAVLA FGNLLVMI+ILHF
Sbjct: 1 MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHF 60
Query: 61 KQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSL 120
KQLH+PTNFL+ASLACADFLVGVTVMPFS VR+VESCWYFG S+C FHTC D +FC++SL
Sbjct: 61 KQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASL 120
Query: 121 FHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEEL 180
FHLC IS+DRYIAVTDPL YPTKFTVSVSGICI +SW + YS ++FYTG ++G+EEL
Sbjct: 121 FHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEEL 180
Query: 181 SDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTES 240
AL C+GGCQ +NQNWVL FL FFIP M+ +Y IFLVA+ QA+KIE+T S+ +S
Sbjct: 181 VVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQS 240
Query: 241 SSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCA 300
SSESYK RVA+RERKAAKTLG+ + AF++SWLPY +D++IDA+M FITP +YEI WC
Sbjct: 241 SSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCV 300
Query: 301 YYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI 345
YYNSAMNPLIYA FY WF KAIK+IV+G+VL+ S+T NLFSE +
Sbjct: 301 YYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEV 345
>gi|223633986 trace amine associated receptor 5 [Homo sapiens]
Length = 337
Score = 304 bits (779), Expect = 7e-83
Identities = 146/330 (44%), Positives = 216/330 (65%), Gaps = 9/330 (2%)
Query: 14 CYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVAS 73
CY VNGSC + + G ++++Y+ G ++ V GN+ V ++ +FK LH+PTNFL+ S
Sbjct: 17 CY-QVNGSCPRTVHTLGIQLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHTPTNFLLLS 75
Query: 74 LACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIA 133
LA AD +G+ V+P S +R+VESCW+FG C HT D FC +S+FHLCFISIDR+ A
Sbjct: 76 LALADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCA 135
Query: 134 VTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGGCQTV 193
+ DPL+YP+KFTV V+ I W +P Y+ YT V + L + + + C+G CQ +
Sbjct: 136 ICDPLLYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRLSQWLEEMPCVGSCQLL 195
Query: 194 VNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTESSSESYKARVARRE 253
+N+ W +F FF+P IMI LY IF+VA RQA++I T SK+ A A+ E
Sbjct: 196 LNKFWGWLNFPLFFVPCLIMISLYVKIFVVATRQAQQI-TTLSKS-------LAGAAKHE 247
Query: 254 RKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYAL 313
RKAAKTLG+ V +++ WLP++ID+++D+ + FITP +++I W AY+NSA NP+IY
Sbjct: 248 RKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFIWFAYFNSACNPIIYVF 307
Query: 314 FYPWFRKAIKVIVTGQVLKNSSATMNLFSE 343
Y WFRKA+K+ ++ +V + T++L+ E
Sbjct: 308 SYQWFRKALKLTLSQKVFSPQTRTVDLYQE 337
>gi|21264324 trace amine associated receptor 1 [Homo sapiens]
Length = 339
Score = 278 bits (712), Expect = 4e-75
Identities = 137/332 (41%), Positives = 204/332 (61%), Gaps = 2/332 (0%)
Query: 14 CYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVAS 73
C+ +N SCVK +S R LY + + + GNL+V++SI HFKQLH+PTN+L+ S
Sbjct: 5 CHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHS 64
Query: 74 LACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIA 133
+A DFL+G VMP+SMVR+ E CWYFG FC HT D+ +S+FHL FISIDRY A
Sbjct: 65 MATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYA 124
Query: 134 VTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEEL-SDALNCIGGCQT 192
V DPL Y K + V + I +SW +P +++ + + + G EE+ ++C GGC
Sbjct: 125 VCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSV 184
Query: 193 VVNQ-NWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTESSSESYKARVAR 251
++ + VLT SF+IP IM+ +Y I+L+A+ QA+ I + K + E
Sbjct: 185 FFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQS 244
Query: 252 RERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIY 311
+ERKA KTLG+ + F+I W P+ I +++D F+ +I P + ++ W Y NS NP++Y
Sbjct: 245 KERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVY 304
Query: 312 ALFYPWFRKAIKVIVTGQVLKNSSATMNLFSE 343
A FYPWFRKA+K+++ G++ + S+ LF E
Sbjct: 305 AFFYPWFRKALKMMLFGKIFQKDSSRCKLFLE 336
>gi|74275344 trace amine associated receptor 2 isoform 1 [Homo
sapiens]
Length = 351
Score = 264 bits (675), Expect = 8e-71
Identities = 125/321 (38%), Positives = 191/321 (59%), Gaps = 9/321 (2%)
Query: 14 CYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVAS 73
C N SC + S G RV +Y + +FGNL ++ISI +FKQLH+PTNFL+ S
Sbjct: 25 CSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILS 84
Query: 74 LACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIA 133
+A DFL+G T+MP+SM+R+VE+CWYFG +FC + D+ +S+FHLC ++IDR+ A
Sbjct: 85 MAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYA 144
Query: 134 VTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGGCQTV 193
+ PL+Y TK T+ V + + W +P ++ V ++ Y DG+E + C C +
Sbjct: 145 ICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVM 204
Query: 194 VNQNWVLTDFLS-FFIPTFIMIILYGNIFLVARRQAKKIENTGSKTESSSESYKARVARR 252
N+ W T F++ FF P +M+ +YG IF V+R+ A I N + ++
Sbjct: 205 FNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLRENQNNQ--------VKK 256
Query: 253 ERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYA 312
++KAAKTLG+ + F++ W P L+D F+ F TP +++ W Y+NS NPLIY
Sbjct: 257 DKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYG 316
Query: 313 LFYPWFRKAIKVIVTGQVLKN 333
FYPWFR+A+K I+ G++ +
Sbjct: 317 FFYPWFRRALKYILLGKIFSS 337
>gi|74275342 trace amine associated receptor 2 isoform 2 [Homo
sapiens]
Length = 306
Score = 255 bits (652), Expect = 4e-68
Identities = 117/300 (39%), Positives = 182/300 (60%), Gaps = 9/300 (3%)
Query: 35 LYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVASLACADFLVGVTVMPFSMVRTV 94
+Y + +FGNL ++ISI +FKQLH+PTNFL+ S+A DFL+G T+MP+SM+R+V
Sbjct: 1 MYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSV 60
Query: 95 ESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGICIS 154
E+CWYFG +FC + D+ +S+FHLC ++IDR+ A+ PL+Y TK T+ V +
Sbjct: 61 ENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLL 120
Query: 155 VSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGGCQTVVNQNWVLTDFLS-FFIPTFIM 213
+ W +P ++ V ++ Y DG+E + C C + N+ W T F++ FF P +M
Sbjct: 121 LCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMM 180
Query: 214 IILYGNIFLVARRQAKKIENTGSKTESSSESYKARVARRERKAAKTLGVTVVAFMISWLP 273
+ +YG IF V+R+ A I N + ++++KAAKTLG+ + F++ W P
Sbjct: 181 VGIYGKIFAVSRKHAHAINNLRENQNNQ--------VKKDKKAAKTLGIVIGVFLLCWFP 232
Query: 274 YSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKN 333
L+D F+ F TP +++ W Y+NS NPLIY FYPWFR+A+K I+ G++ +
Sbjct: 233 CFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSS 292
>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
Length = 359
Score = 178 bits (452), Expect = 6e-45
Identities = 105/339 (30%), Positives = 171/339 (50%), Gaps = 26/339 (7%)
Query: 27 FSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHS-PTNFLVASLACADFLVGVTV 85
F +V+L ++A+ GNLLVM+++ +QL TN+ + SLA AD LV V V
Sbjct: 14 FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLV 73
Query: 86 MPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAV-TDPLVYPTKF 144
MPF + V+ W +G FC T DV +S+FHLC IS+DRY A+ PLVY K
Sbjct: 74 MPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKM 133
Query: 145 TVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGG-----CQTVVNQNWV 199
T + + W++P S G + G+ +L + C +VN+ +
Sbjct: 134 TPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYA 193
Query: 200 LT-DFLSFFIPTFIMIILYGNIFLVARRQAKKI---ENTGSKTES---SSESYKARVARR 252
+T ++F+IP +M++ Y I++ A+ A +I + G+ +ES S++ + R
Sbjct: 194 ITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRT 253
Query: 253 ERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYA 312
E KAAKTL + + F + W P+ + +++D F+ + P ++ W Y NS +NP +YA
Sbjct: 254 ETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYA 313
Query: 313 LFYPWFRKAIKVI------------VTGQVLKNSSATMN 339
FR+A +I + GQ + S+ T+N
Sbjct: 314 FLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTIN 352
>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
Length = 428
Score = 178 bits (452), Expect = 6e-45
Identities = 105/339 (30%), Positives = 171/339 (50%), Gaps = 26/339 (7%)
Query: 27 FSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHS-PTNFLVASLACADFLVGVTV 85
F +V+L ++A+ GNLLVM+++ +QL TN+ + SLA AD LV V V
Sbjct: 14 FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLV 73
Query: 86 MPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAV-TDPLVYPTKF 144
MPF + V+ W +G FC T DV +S+FHLC IS+DRY A+ PLVY K
Sbjct: 74 MPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKM 133
Query: 145 TVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGG-----CQTVVNQNWV 199
T + + W++P S G + G+ +L + C +VN+ +
Sbjct: 134 TPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYA 193
Query: 200 LT-DFLSFFIPTFIMIILYGNIFLVARRQAKKI---ENTGSKTES---SSESYKARVARR 252
+T ++F+IP +M++ Y I++ A+ A +I + G+ +ES S++ + R
Sbjct: 194 ITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRT 253
Query: 253 ERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYA 312
E KAAKTL + + F + W P+ + +++D F+ + P ++ W Y NS +NP +YA
Sbjct: 254 ETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYA 313
Query: 313 LFYPWFRKAIKVI------------VTGQVLKNSSATMN 339
FR+A +I + GQ + S+ T+N
Sbjct: 314 FLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTIN 352
>gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]
Length = 402
Score = 178 bits (452), Expect = 6e-45
Identities = 108/353 (30%), Positives = 174/353 (49%), Gaps = 40/353 (11%)
Query: 27 FSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHS-PTNFLVASLACADFLVGVTV 85
F +V+L ++A+ GNLLVM+++ +QL TN+ + SLA AD LV V V
Sbjct: 14 FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLV 73
Query: 86 MPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAV-TDPLVYPTKF 144
MPF + V+ W +G FC T DV +S+FHLC IS+DRY A+ PLVY K
Sbjct: 74 MPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKM 133
Query: 145 TVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGG--------------- 189
T + + W++P S G + G+ +L +LN G
Sbjct: 134 TPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNS 193
Query: 190 ----CQTVVNQNWVLT-DFLSFFIPTFIMIILYGNIFLVARRQAKKI---ENTGSKTES- 240
C +VN+ + +T ++F+IP +M++ Y I++ A+ A +I + G+ +ES
Sbjct: 194 NSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESR 253
Query: 241 --SSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCW 298
S++ + R E KAAKTL + + F + W P+ + +++D F+ + P ++ W
Sbjct: 254 PQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLW 313
Query: 299 CAYYNSAMNPLIYALFYPWFRKAIKVI------------VTGQVLKNSSATMN 339
Y NS +NP +YA FR+A +I + GQ + S+ T+N
Sbjct: 314 LGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTIN 366
>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
Length = 360
Score = 178 bits (452), Expect = 6e-45
Identities = 105/339 (30%), Positives = 171/339 (50%), Gaps = 26/339 (7%)
Query: 27 FSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHS-PTNFLVASLACADFLVGVTV 85
F +V+L ++A+ GNLLVM+++ +QL TN+ + SLA AD LV V V
Sbjct: 14 FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLV 73
Query: 86 MPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAV-TDPLVYPTKF 144
MPF + V+ W +G FC T DV +S+FHLC IS+DRY A+ PLVY K
Sbjct: 74 MPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKM 133
Query: 145 TVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGG-----CQTVVNQNWV 199
T + + W++P S G + G+ +L + C +VN+ +
Sbjct: 134 TPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYA 193
Query: 200 LT-DFLSFFIPTFIMIILYGNIFLVARRQAKKI---ENTGSKTES---SSESYKARVARR 252
+T ++F+IP +M++ Y I++ A+ A +I + G+ +ES S++ + R
Sbjct: 194 ITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRT 253
Query: 253 ERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYA 312
E KAAKTL + + F + W P+ + +++D F+ + P ++ W Y NS +NP +YA
Sbjct: 254 ETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYA 313
Query: 313 LFYPWFRKAIKVI------------VTGQVLKNSSATMN 339
FR+A +I + GQ + S+ T+N
Sbjct: 314 FLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTIN 352
>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
Length = 387
Score = 178 bits (452), Expect = 6e-45
Identities = 105/339 (30%), Positives = 171/339 (50%), Gaps = 26/339 (7%)
Query: 27 FSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHS-PTNFLVASLACADFLVGVTV 85
F +V+L ++A+ GNLLVM+++ +QL TN+ + SLA AD LV V V
Sbjct: 14 FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLV 73
Query: 86 MPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAV-TDPLVYPTKF 144
MPF + V+ W +G FC T DV +S+FHLC IS+DRY A+ PLVY K
Sbjct: 74 MPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKM 133
Query: 145 TVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGG-----CQTVVNQNWV 199
T + + W++P S G + G+ +L + C +VN+ +
Sbjct: 134 TPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYA 193
Query: 200 LT-DFLSFFIPTFIMIILYGNIFLVARRQAKKI---ENTGSKTES---SSESYKARVARR 252
+T ++F+IP +M++ Y I++ A+ A +I + G+ +ES S++ + R
Sbjct: 194 ITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRT 253
Query: 253 ERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYA 312
E KAAKTL + + F + W P+ + +++D F+ + P ++ W Y NS +NP +YA
Sbjct: 254 ETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYA 313
Query: 313 LFYPWFRKAIKVI------------VTGQVLKNSSATMN 339
FR+A +I + GQ + S+ T+N
Sbjct: 314 FLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTIN 352
>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
Length = 378
Score = 178 bits (452), Expect = 6e-45
Identities = 105/339 (30%), Positives = 171/339 (50%), Gaps = 26/339 (7%)
Query: 27 FSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHS-PTNFLVASLACADFLVGVTV 85
F +V+L ++A+ GNLLVM+++ +QL TN+ + SLA AD LV V V
Sbjct: 14 FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLV 73
Query: 86 MPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAV-TDPLVYPTKF 144
MPF + V+ W +G FC T DV +S+FHLC IS+DRY A+ PLVY K
Sbjct: 74 MPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKM 133
Query: 145 TVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGG-----CQTVVNQNWV 199
T + + W++P S G + G+ +L + C +VN+ +
Sbjct: 134 TPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYA 193
Query: 200 LT-DFLSFFIPTFIMIILYGNIFLVARRQAKKI---ENTGSKTES---SSESYKARVARR 252
+T ++F+IP +M++ Y I++ A+ A +I + G+ +ES S++ + R
Sbjct: 194 ITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRT 253
Query: 253 ERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYA 312
E KAAKTL + + F + W P+ + +++D F+ + P ++ W Y NS +NP +YA
Sbjct: 254 ETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYA 313
Query: 313 LFYPWFRKAIKVI------------VTGQVLKNSSATMN 339
FR+A +I + GQ + S+ T+N
Sbjct: 314 FLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTIN 352
>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
Length = 388
Score = 178 bits (452), Expect = 6e-45
Identities = 105/339 (30%), Positives = 171/339 (50%), Gaps = 26/339 (7%)
Query: 27 FSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHS-PTNFLVASLACADFLVGVTV 85
F +V+L ++A+ GNLLVM+++ +QL TN+ + SLA AD LV V V
Sbjct: 14 FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLV 73
Query: 86 MPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAV-TDPLVYPTKF 144
MPF + V+ W +G FC T DV +S+FHLC IS+DRY A+ PLVY K
Sbjct: 74 MPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKM 133
Query: 145 TVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGG-----CQTVVNQNWV 199
T + + W++P S G + G+ +L + C +VN+ +
Sbjct: 134 TPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYA 193
Query: 200 LT-DFLSFFIPTFIMIILYGNIFLVARRQAKKI---ENTGSKTES---SSESYKARVARR 252
+T ++F+IP +M++ Y I++ A+ A +I + G+ +ES S++ + R
Sbjct: 194 ITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRT 253
Query: 253 ERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYA 312
E KAAKTL + + F + W P+ + +++D F+ + P ++ W Y NS +NP +YA
Sbjct: 254 ETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYA 313
Query: 313 LFYPWFRKAIKVI------------VTGQVLKNSSATMN 339
FR+A +I + GQ + S+ T+N
Sbjct: 314 FLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTIN 352
>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
Length = 455
Score = 166 bits (419), Expect = 4e-41
Identities = 107/336 (31%), Positives = 170/336 (50%), Gaps = 39/336 (11%)
Query: 26 PFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVASLACADFLVGVTV 85
P + ++L ++ G + V GN+LV++S+ + LHS T++ + +LA AD L+ TV
Sbjct: 20 PVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTV 79
Query: 86 MPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFT 145
+PFS + V W FGR FC DV C +S+ LC ISIDRYI V+ PL YPT T
Sbjct: 80 LPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVT 139
Query: 146 VSVSGICISVSWILPLMYS-GAVFYTGVYDDGLEELSDALNCIGGCQTVVNQNWVLTDFL 204
+ + W L L+ S G +F G + + I CQ +VL L
Sbjct: 140 QRRGLMALLCVWALSLVISIGPLF-------GWRQPAPEDETI--CQINEEPGYVLFSAL 190
Query: 205 -SFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTESSSESYKARVAR------------ 251
SF++P I++++Y +++VA+R+++ +++ +S SE R+ R
Sbjct: 191 GSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMAS 250
Query: 252 ---------------RERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPA-CIYEI 295
RE+KAAKTLG+ V F++ WLP+ + I +F P+ +++I
Sbjct: 251 AKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKI 310
Query: 296 CCWCAYYNSAMNPLIYALFYPWFRKAIKVIVTGQVL 331
W Y NS +NP+IY F+KA + ++ Q L
Sbjct: 311 VFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCL 346
>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
Length = 466
Score = 166 bits (419), Expect = 4e-41
Identities = 107/336 (31%), Positives = 170/336 (50%), Gaps = 39/336 (11%)
Query: 26 PFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVASLACADFLVGVTV 85
P + ++L ++ G + V GN+LV++S+ + LHS T++ + +LA AD L+ TV
Sbjct: 20 PVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTV 79
Query: 86 MPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFT 145
+PFS + V W FGR FC DV C +S+ LC ISIDRYI V+ PL YPT T
Sbjct: 80 LPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVT 139
Query: 146 VSVSGICISVSWILPLMYS-GAVFYTGVYDDGLEELSDALNCIGGCQTVVNQNWVLTDFL 204
+ + W L L+ S G +F G + + I CQ +VL L
Sbjct: 140 QRRGLMALLCVWALSLVISIGPLF-------GWRQPAPEDETI--CQINEEPGYVLFSAL 190
Query: 205 -SFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTESSSESYKARVAR------------ 251
SF++P I++++Y +++VA+R+++ +++ +S SE R+ R
Sbjct: 191 GSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMAS 250
Query: 252 ---------------RERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPA-CIYEI 295
RE+KAAKTLG+ V F++ WLP+ + I +F P+ +++I
Sbjct: 251 AKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKI 310
Query: 296 CCWCAYYNSAMNPLIYALFYPWFRKAIKVIVTGQVL 331
W Y NS +NP+IY F+KA + ++ Q L
Sbjct: 311 VFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCL 346
>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
Length = 475
Score = 166 bits (419), Expect = 4e-41
Identities = 107/336 (31%), Positives = 170/336 (50%), Gaps = 39/336 (11%)
Query: 26 PFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVASLACADFLVGVTV 85
P + ++L ++ G + V GN+LV++S+ + LHS T++ + +LA AD L+ TV
Sbjct: 20 PVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTV 79
Query: 86 MPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFT 145
+PFS + V W FGR FC DV C +S+ LC ISIDRYI V+ PL YPT T
Sbjct: 80 LPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVT 139
Query: 146 VSVSGICISVSWILPLMYS-GAVFYTGVYDDGLEELSDALNCIGGCQTVVNQNWVLTDFL 204
+ + W L L+ S G +F G + + I CQ +VL L
Sbjct: 140 QRRGLMALLCVWALSLVISIGPLF-------GWRQPAPEDETI--CQINEEPGYVLFSAL 190
Query: 205 -SFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTESSSESYKARVAR------------ 251
SF++P I++++Y +++VA+R+++ +++ +S SE R+ R
Sbjct: 191 GSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMAS 250
Query: 252 ---------------RERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPA-CIYEI 295
RE+KAAKTLG+ V F++ WLP+ + I +F P+ +++I
Sbjct: 251 AKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKI 310
Query: 296 CCWCAYYNSAMNPLIYALFYPWFRKAIKVIVTGQVL 331
W Y NS +NP+IY F+KA + ++ Q L
Sbjct: 311 VFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCL 346
>gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]
Length = 429
Score = 166 bits (419), Expect = 4e-41
Identities = 107/336 (31%), Positives = 170/336 (50%), Gaps = 39/336 (11%)
Query: 26 PFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVASLACADFLVGVTV 85
P + ++L ++ G + V GN+LV++S+ + LHS T++ + +LA AD L+ TV
Sbjct: 20 PVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTV 79
Query: 86 MPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFT 145
+PFS + V W FGR FC DV C +S+ LC ISIDRYI V+ PL YPT T
Sbjct: 80 LPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVT 139
Query: 146 VSVSGICISVSWILPLMYS-GAVFYTGVYDDGLEELSDALNCIGGCQTVVNQNWVLTDFL 204
+ + W L L+ S G +F G + + I CQ +VL L
Sbjct: 140 QRRGLMALLCVWALSLVISIGPLF-------GWRQPAPEDETI--CQINEEPGYVLFSAL 190
Query: 205 -SFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTESSSESYKARVAR------------ 251
SF++P I++++Y +++VA+R+++ +++ +S SE R+ R
Sbjct: 191 GSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMAS 250
Query: 252 ---------------RERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPA-CIYEI 295
RE+KAAKTLG+ V F++ WLP+ + I +F P+ +++I
Sbjct: 251 AKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKI 310
Query: 296 CCWCAYYNSAMNPLIYALFYPWFRKAIKVIVTGQVL 331
W Y NS +NP+IY F+KA + ++ Q L
Sbjct: 311 VFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCL 346
>gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]
Length = 413
Score = 158 bits (400), Expect = 6e-39
Identities = 96/312 (30%), Positives = 157/312 (50%), Gaps = 27/312 (8%)
Query: 38 VFGFGAVLA------VFGNLLVMISILHFKQLHSPTNFLVASLACADFLVGVTVMPFSMV 91
V G G V++ VFGN+LV+ +I F++L + TN+ + SLACAD ++G+ V+PF
Sbjct: 33 VVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAA 92
Query: 92 RTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGI 151
+ W FG +C F T DV +S+ LC I++DRY A+T P Y + T + + +
Sbjct: 93 HILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARV 152
Query: 152 CISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGG---CQTVVNQNW-VLTDFLSFF 207
I + WI+ + S Y +E A+NC C NQ + + + +SF+
Sbjct: 153 IILMVWIVSGLTSFLPIQMHWYRATHQE---AINCYANETCCDFFTNQAYAIASSIVSFY 209
Query: 208 IPTFIMIILYGNIFLVARRQAKKIENTGSKTESSSESY-------------KARVARRER 254
+P IM+ +Y +F A+RQ +KI+ + + + S ++ +E
Sbjct: 210 VPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEH 269
Query: 255 KAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYALF 314
KA KTLG+ + F + WLP+ I +++ + +Y + W Y NS NPLIY
Sbjct: 270 KALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCR- 328
Query: 315 YPWFRKAIKVIV 326
P FR A + ++
Sbjct: 329 SPDFRIAFQELL 340
>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
Length = 397
Score = 154 bits (390), Expect = 9e-38
Identities = 101/317 (31%), Positives = 158/317 (49%), Gaps = 13/317 (4%)
Query: 28 SPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVASLACADFLVGVTVMP 87
S ++ + +V ++ V GN++V +++ ++L + TN + SLA D L+G+ V+P
Sbjct: 14 STACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLP 73
Query: 88 FSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFTVS 147
FS + + W FG+ FC +T DV C +S+ +L IS+DRY AV DPL YP T
Sbjct: 74 FSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPV 133
Query: 148 VSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGGCQTVVNQNWVLTD-FLSF 206
I + + W++ + S + G + E S + C+ VN+ + L D ++F
Sbjct: 134 RVAISLVLIWVISITLSFLSIHLGW--NSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTF 191
Query: 207 FIPTFIMIILYGNIFLVARRQAKKIENTGSKTESSSESYKARVARRERKAAKTLGVTVVA 266
++P IM I Y IF VAR QAK+I + S+KA RE KA TL + A
Sbjct: 192 YLPLLIMCITYYRIFKVARDQAKRINHI--------SSWKAATI-REHKATVTLAAVMGA 242
Query: 267 FMISWLPYSIDSLIDAFMGFITPACIYE-ICCWCAYYNSAMNPLIYALFYPWFRKAIKVI 325
F+I W PY + G + E I W Y NSA+NP++YA FR + +
Sbjct: 243 FIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQL 302
Query: 326 VTGQVLKNSSATMNLFS 342
++ +S +L S
Sbjct: 303 FCCRLANRNSHKTSLRS 319
>gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]
Length = 359
Score = 154 bits (390), Expect = 9e-38
Identities = 101/317 (31%), Positives = 158/317 (49%), Gaps = 13/317 (4%)
Query: 28 SPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVASLACADFLVGVTVMP 87
S ++ + +V ++ V GN++V +++ ++L + TN + SLA D L+G+ V+P
Sbjct: 14 STACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLP 73
Query: 88 FSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFTVS 147
FS + + W FG+ FC +T DV C +S+ +L IS+DRY AV DPL YP T
Sbjct: 74 FSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPV 133
Query: 148 VSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGGCQTVVNQNWVLTD-FLSF 206
I + + W++ + S + G + E S + C+ VN+ + L D ++F
Sbjct: 134 RVAISLVLIWVISITLSFLSIHLGW--NSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTF 191
Query: 207 FIPTFIMIILYGNIFLVARRQAKKIENTGSKTESSSESYKARVARRERKAAKTLGVTVVA 266
++P IM I Y IF VAR QAK+I + S+KA RE KA TL + A
Sbjct: 192 YLPLLIMCITYYRIFKVARDQAKRINHI--------SSWKAATI-REHKATVTLAAVMGA 242
Query: 267 FMISWLPYSIDSLIDAFMGFITPACIYE-ICCWCAYYNSAMNPLIYALFYPWFRKAIKVI 325
F+I W PY + G + E I W Y NSA+NP++YA FR + +
Sbjct: 243 FIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQL 302
Query: 326 VTGQVLKNSSATMNLFS 342
++ +S +L S
Sbjct: 303 FCCRLANRNSHKTSLRS 319
>gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo
sapiens]
Length = 390
Score = 152 bits (384), Expect = 4e-37
Identities = 105/349 (30%), Positives = 165/349 (47%), Gaps = 67/349 (19%)
Query: 32 RVILYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVASLACADFLVGVTVMPFSMV 91
+V+L ++ + N V+ ++ ++LH+P N+L+ASLA D LV + VMP S +
Sbjct: 49 KVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTM 108
Query: 92 RTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGI 151
TV W G+ C F D+ C +S+ HLC I++DRY A+TD + Y K T + +
Sbjct: 109 YTVTGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAV 168
Query: 152 CISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGGCQTVVNQNWVLTDFLS----FF 207
I++ W+ + S F+ EE+S+ VVN + +L S F+
Sbjct: 169 MIALVWVFSISISLPPFFWR-QAKAEEEVSEC---------VVNTDHILYTVYSTVGAFY 218
Query: 208 IPTFIMIILYGNIFLVAR---------RQAKKI-------ENTGS--------------K 237
PT ++I LYG I++ AR R K++ ++ GS
Sbjct: 219 FPTLLLIALYGRIYVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVP 278
Query: 238 TESSSESY---------------KARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDA 282
+ES S Y K +A RERKA KTLG+ + AF++ WLP+ I SL+
Sbjct: 279 SESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLV-- 336
Query: 283 FMGFITPAC-----IYEICCWCAYYNSAMNPLIYALFYPWFRKAIKVIV 326
M AC I++ W Y NS +NP+IY + F++A ++
Sbjct: 337 -MPICKDACWFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLI 384
>gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo
sapiens]
Length = 377
Score = 151 bits (381), Expect = 9e-37
Identities = 105/342 (30%), Positives = 161/342 (47%), Gaps = 55/342 (16%)
Query: 32 RVILYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVASLACADFLVGVTVMPFSMV 91
++ L +V + V N V+ +IL ++LH+P N+L+ SLA D LV + VMP S+
Sbjct: 38 KISLAVVLSVITLATVLSNAFVLTTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIA 97
Query: 92 RTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGI 151
T+ W FG+ C D+ C +S+ HLC I++DRY A+TD L Y + T +
Sbjct: 98 YTITHTWNFGQILCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAT 157
Query: 152 CISVSWILPLMYS-GAVFYTGVYDDGLEELSDALNCIGGCQTVVNQNWVLTDFLSFFIPT 210
I++ W + + S +F+ EE+SD L T + + +F+IP+
Sbjct: 158 MIAIVWAISICISIPPLFWRQA--KAQEEMSDCL-----VNTSQISYTIYSTCGAFYIPS 210
Query: 211 FIMIILYGNIFLVARRQ--------AKKIEN----TGS---------------------- 236
++IILYG I+ AR + K+ TGS
Sbjct: 211 VLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNSSLHEGHSHSAGS 270
Query: 237 ---------KTESSSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMG-- 285
K S+ K A RERKA K LG+ + AF+I WLP+ + SL+
Sbjct: 271 PLFFNHVKIKLADSALERKRISAARERKATKILGIILGAFIICWLPFFVVSLVLPICRDS 330
Query: 286 -FITPACIYEICCWCAYYNSAMNPLIYALFYPWFRKAIKVIV 326
+I PA +++ W Y NS +NP+IY +F FR+A + IV
Sbjct: 331 CWIHPA-LFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKIV 371
>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
Length = 520
Score = 151 bits (381), Expect = 9e-37
Identities = 99/317 (31%), Positives = 154/317 (48%), Gaps = 40/317 (12%)
Query: 37 IVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVES 96
+V G + A+ GN+LV++S+ + L +PTN+ + +LA AD L+ TV+PFS V
Sbjct: 50 LVLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLG 109
Query: 97 CWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVS 156
W GR FC DV C +S+ LC ISIDRYI V L YPT T + + +
Sbjct: 110 YWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSV 169
Query: 157 WILPLMYSGAVFYTGVYDDGLEELSDALNCIGGCQTVVNQNWVLTDFL-SFFIPTFIMII 215
W+L + S G +E A N C + L L SF+IP ++++
Sbjct: 170 WVLSTVISIGPLL------GWKE--PAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILV 221
Query: 216 LYGNIFLVARRQAKKIE------------------------NTGSKTESSSESYKARVA- 250
+Y +++VA+R K +E +T S T++ + ++ +A
Sbjct: 222 MYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAV 281
Query: 251 -----RRERKAAKTLGVTVVAFMISWLPYSID-SLIDAFMGFITPACIYEICCWCAYYNS 304
RE+KAAKTLG+ V F++ WLP+ I L F P ++++ W Y+NS
Sbjct: 282 KLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNS 341
Query: 305 AMNPLIYALFYPWFRKA 321
+NP+IY F++A
Sbjct: 342 CLNPIIYPCSSKEFKRA 358
>gi|4503383 dopamine receptor D1 [Homo sapiens]
Length = 446
Score = 144 bits (364), Expect = 9e-35
Identities = 99/310 (31%), Positives = 152/310 (49%), Gaps = 32/310 (10%)
Query: 47 VFGNLLVMISILHFKQLHSP-TNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFC 105
+ GN LV +++ F+ L S TNF V SLA +D LV V VMP+ V + W FG SFC
Sbjct: 38 LLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFG-SFC 96
Query: 106 TFHTCCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSG 165
D+ +S+ +LC IS+DRY A++ P Y K T + I ISV+W L ++ S
Sbjct: 97 NIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISF 156
Query: 166 AVFYTGVYDDGLEELSDA-----LNCIGGCQTVVNQNWVL-TDFLSFFIPTFIMIILYGN 219
+ SD I C + +++ + + + +SF+IP IMI+ Y
Sbjct: 157 IPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTR 216
Query: 220 IFLVARRQAKKI----------------ENTGSKTESSSESYKARVA-RRERKAAKTLGV 262
I+ +A++Q ++I G E S +++ +RE K KTL V
Sbjct: 217 IYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSV 276
Query: 263 TVVAFMISWLPYSIDSLIDAFMGF--ITPACI----YEICCWCAYYNSAMNPLIYALFYP 316
+ F+ WLP+ I + I F G P CI +++ W + NS++NP+IYA F
Sbjct: 277 IMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYA-FNA 335
Query: 317 WFRKAIKVIV 326
FRKA ++
Sbjct: 336 DFRKAFSTLL 345
>gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]
Length = 432
Score = 144 bits (362), Expect = 2e-34
Identities = 100/333 (30%), Positives = 160/333 (48%), Gaps = 46/333 (13%)
Query: 17 NVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVASLAC 76
N +G +I + +V++ + +L + GN LV+IS+ K+L P+N+L+ SLA
Sbjct: 66 NASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLAL 125
Query: 77 ADFLVGVTVMPF-SMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVT 135
AD V V VMPF S+ + W FG FC DV C +S+ LC ISIDRY+ +T
Sbjct: 126 ADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGIT 185
Query: 136 DPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGGCQTVVN 195
PL YP V +G C++ + + S ++ ++ + ++D C+ ++
Sbjct: 186 RPLTYP----VRQNGKCMAKMILSVWLLSASITLPPLF-GWAQNVNDDKVCL------IS 234
Query: 196 QNWVLTDF---LSFFIPTFIMIILYGNIFLVARRQAKKIENTG-SKTESSS--------- 242
Q++ T + ++F+IP +M+ +Y I+ AR+ A K + G + E S
Sbjct: 235 QDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVK 294
Query: 243 -----------------ESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMG 285
E + +RE+KAA TLG+ V AF + WLP+ + S F+
Sbjct: 295 LQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFIC 354
Query: 286 FITPACI----YEICCWCAYYNSAMNPLIYALF 314
+ +CI W Y NS +NP IYA F
Sbjct: 355 GTSCSCIPLWVERTFLWLGYANSLINPFIYAFF 387
>gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]
Length = 479
Score = 144 bits (362), Expect = 2e-34
Identities = 100/333 (30%), Positives = 160/333 (48%), Gaps = 46/333 (13%)
Query: 17 NVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVASLAC 76
N +G +I + +V++ + +L + GN LV+IS+ K+L P+N+L+ SLA
Sbjct: 66 NASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLAL 125
Query: 77 ADFLVGVTVMPF-SMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVT 135
AD V V VMPF S+ + W FG FC DV C +S+ LC ISIDRY+ +T
Sbjct: 126 ADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGIT 185
Query: 136 DPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGGCQTVVN 195
PL YP V +G C++ + + S ++ ++ + ++D C+ ++
Sbjct: 186 RPLTYP----VRQNGKCMAKMILSVWLLSASITLPPLF-GWAQNVNDDKVCL------IS 234
Query: 196 QNWVLTDF---LSFFIPTFIMIILYGNIFLVARRQAKKIENTG-SKTESSS--------- 242
Q++ T + ++F+IP +M+ +Y I+ AR+ A K + G + E S
Sbjct: 235 QDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVK 294
Query: 243 -----------------ESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMG 285
E + +RE+KAA TLG+ V AF + WLP+ + S F+
Sbjct: 295 LQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFIC 354
Query: 286 FITPACI----YEICCWCAYYNSAMNPLIYALF 314
+ +CI W Y NS +NP IYA F
Sbjct: 355 GTSCSCIPLWVERTFLWLGYANSLINPFIYAFF 387
>gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens]
Length = 445
Score = 144 bits (362), Expect = 2e-34
Identities = 100/333 (30%), Positives = 160/333 (48%), Gaps = 46/333 (13%)
Query: 17 NVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVASLAC 76
N +G +I + +V++ + +L + GN LV+IS+ K+L P+N+L+ SLA
Sbjct: 66 NASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLAL 125
Query: 77 ADFLVGVTVMPF-SMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVT 135
AD V V VMPF S+ + W FG FC DV C +S+ LC ISIDRY+ +T
Sbjct: 126 ADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGIT 185
Query: 136 DPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGGCQTVVN 195
PL YP V +G C++ + + S ++ ++ + ++D C+ ++
Sbjct: 186 RPLTYP----VRQNGKCMAKMILSVWLLSASITLPPLF-GWAQNVNDDKVCL------IS 234
Query: 196 QNWVLTDF---LSFFIPTFIMIILYGNIFLVARRQAKKIENTG-SKTESSS--------- 242
Q++ T + ++F+IP +M+ +Y I+ AR+ A K + G + E S
Sbjct: 235 QDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVK 294
Query: 243 -----------------ESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMG 285
E + +RE+KAA TLG+ V AF + WLP+ + S F+
Sbjct: 295 LQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFIC 354
Query: 286 FITPACI----YEICCWCAYYNSAMNPLIYALF 314
+ +CI W Y NS +NP IYA F
Sbjct: 355 GTSCSCIPLWVERTFLWLGYANSLINPFIYAFF 387
>gi|10835197 5-hydroxytryptamine (serotonin) receptor 1F [Homo
sapiens]
Length = 366
Score = 141 bits (356), Expect = 7e-34
Identities = 103/352 (29%), Positives = 161/352 (45%), Gaps = 67/352 (19%)
Query: 31 SRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVASLACADFLVGVTVMPFSM 90
S++++ + A++ N LV+ +I+ ++LH P N+L+ SLA DFLV V VMPFS+
Sbjct: 22 SKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSI 81
Query: 91 VRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFTVSVSG 150
V V W G+ C D+ C S+ HL I++DRY A+TD + Y K T +G
Sbjct: 82 VYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHAG 141
Query: 151 ICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGGCQTVVNQNWVLTDFLSFFIPT 210
I I++ WI+ + S + ++ CI +V+ + + F +F+IP
Sbjct: 142 IMITIVWIISVFISMPPLFWRHQGTSRDD-----ECIIKHDHIVST--IYSTFGAFYIPL 194
Query: 211 FIMIILYGNIFLVA-----RRQAKKI-----------ENTGSKTESSSESYKARVA---- 250
+++ILY I+ A +RQA +I E+ T+S S SY +
Sbjct: 195 ALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKSVSTSYVLEKSLSDP 254
Query: 251 -------------------------------RRERKAAKTLGVTVVAFMISWLPYSIDSL 279
RERKAA TLG+ + AF+I WLP+ + L
Sbjct: 255 STDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKEL 314
Query: 280 IDAFMGFITPAC-----IYEICCWCAYYNSAMNPLIYALFYPWFRKAIKVIV 326
+ + C + W Y NS +NPLIY +F F+KA + +V
Sbjct: 315 VVN----VCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLV 362
>gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo
sapiens]
Length = 440
Score = 135 bits (339), Expect = 7e-32
Identities = 90/318 (28%), Positives = 153/318 (48%), Gaps = 27/318 (8%)
Query: 26 PFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVASLACADFLVGVTV 85
P +PG + L N L++ I L + +NF + SL +D +VG+ V
Sbjct: 20 PSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVV 79
Query: 86 MPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFT 145
MP +M+ + W R C T DV C +S+ +LC IS+DRY+ + PL Y + T
Sbjct: 80 MPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMT 139
Query: 146 VSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCI-GGCQTVVNQNWVL-TDF 203
+ + +W L + S G + EL A + G C+ + + +VL
Sbjct: 140 PLRALALVLGAWSLAALASFLPLLLGWH-----ELGHARPPVPGQCRLLASLPFVLVASG 194
Query: 204 LSFFIPTFIMIILYGNIFLVARRQAKKIEN--TGSKTESS-----------------SES 244
L+FF+P+ + Y I L AR+QA ++ + TG +++S S
Sbjct: 195 LTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRR 254
Query: 245 YKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNS 304
+ +R+ KA+ TLG+ + F ++WLP+ + +++ A I+P ++++ W Y NS
Sbjct: 255 LATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG-LFDVLTWLGYCNS 313
Query: 305 AMNPLIYALFYPWFRKAI 322
MNP+IY LF F++A+
Sbjct: 314 TMNPIIYPLFMRDFKRAL 331
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.329 0.140 0.446
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,253,207
Number of Sequences: 37866
Number of extensions: 436364
Number of successful extensions: 3053
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 559
Number of HSP's successfully gapped in prelim test: 175
Number of HSP's that attempted gapping in prelim test: 1487
Number of HSP's gapped (non-prelim): 965
length of query: 345
length of database: 18,247,518
effective HSP length: 103
effective length of query: 242
effective length of database: 14,347,320
effective search space: 3472051440
effective search space used: 3472051440
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.