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Search of human proteins with 27894357
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27894357 nuclear receptor subfamily 4, group A, member 3
isoform a [Homo sapiens]
(626 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27894361 nuclear receptor subfamily 4, group A, member 3 isof... 1290 0.0
gi|27894357 nuclear receptor subfamily 4, group A, member 3 isof... 1290 0.0
gi|27894355 nuclear receptor subfamily 4, group A, member 3 isof... 1290 0.0
gi|27894359 nuclear receptor subfamily 4, group A, member 3 isof... 880 0.0
gi|5453822 nuclear receptor subfamily 4, group A, member 2 [Homo... 652 0.0
gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Hom... 509 e-144
gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Hom... 509 e-144
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 197 2e-50
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 197 2e-50
gi|11415052 retinoid X receptor, beta [Homo sapiens] 188 1e-47
gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens] 188 1e-47
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens] 187 3e-47
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens] 185 1e-46
gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens] 183 4e-46
gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens] 179 7e-45
gi|45545429 estrogen-related receptor gamma isoform 2 [Homo sapi... 174 2e-43
gi|45545427 estrogen-related receptor gamma isoform 2 [Homo sapi... 174 2e-43
gi|45545433 estrogen-related receptor gamma isoform 1 [Homo sapi... 174 2e-43
gi|197209821 estrogen-related receptor gamma isoform 2 [Homo sap... 174 2e-43
gi|4506755 retinoid X receptor, alpha [Homo sapiens] 173 4e-43
gi|18860920 estrogen-related receptor alpha [Homo sapiens] 164 2e-40
gi|238550159 estrogen-related receptor beta [Homo sapiens] 164 2e-40
gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo... 159 7e-39
gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens] 154 2e-37
gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens] 154 2e-37
gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens] 154 2e-37
gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens] 154 2e-37
gi|14149746 nuclear receptor subfamily 2, group F, member 2 isof... 150 3e-36
gi|194294519 nuclear receptor subfamily 1, group H, member 3 iso... 147 4e-35
gi|194294517 nuclear receptor subfamily 1, group H, member 3 iso... 147 4e-35
>gi|27894361 nuclear receptor subfamily 4, group A, member 3 isoform
b [Homo sapiens]
Length = 637
Score = 1290 bits (3337), Expect = 0.0
Identities = 626/626 (100%), Positives = 626/626 (100%)
Query: 1 MPCVQAQYSPSPPGSSYAAQTYSSEYTTEIMNPDYTKLTMDLGSTEITATATTSLPSIST 60
MPCVQAQYSPSPPGSSYAAQTYSSEYTTEIMNPDYTKLTMDLGSTEITATATTSLPSIST
Sbjct: 12 MPCVQAQYSPSPPGSSYAAQTYSSEYTTEIMNPDYTKLTMDLGSTEITATATTSLPSIST 71
Query: 61 FVEGYSSNYELKPSCVYQMQRPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQHQQPSIPPA 120
FVEGYSSNYELKPSCVYQMQRPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQHQQPSIPPA
Sbjct: 72 FVEGYSSNYELKPSCVYQMQRPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQHQQPSIPPA 131
Query: 121 SSPEDEVLPSTSMYFKQSPPSTPTTPAFPPQAGALWDEALPSAPGCIAPGPLLDPPMKAV 180
SSPEDEVLPSTSMYFKQSPPSTPTTPAFPPQAGALWDEALPSAPGCIAPGPLLDPPMKAV
Sbjct: 132 SSPEDEVLPSTSMYFKQSPPSTPTTPAFPPQAGALWDEALPSAPGCIAPGPLLDPPMKAV 191
Query: 181 PTVAGARFPLFHFKPSPPHPPAPSPAGGHHLGYDPTAAAALSLPLGAAAAAGSQAAALES 240
PTVAGARFPLFHFKPSPPHPPAPSPAGGHHLGYDPTAAAALSLPLGAAAAAGSQAAALES
Sbjct: 192 PTVAGARFPLFHFKPSPPHPPAPSPAGGHHLGYDPTAAAALSLPLGAAAAAGSQAAALES 251
Query: 241 HPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAA 300
HPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAA
Sbjct: 252 HPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAA 311
Query: 301 CQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKE 360
CQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKE
Sbjct: 312 CQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKE 371
Query: 361 VVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRALTDSTPRDLDYSRYC 420
VVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRALTDSTPRDLDYSRYC
Sbjct: 372 VVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRALTDSTPRDLDYSRYC 431
Query: 421 PTDQAAAGTDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVL 480
PTDQAAAGTDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVL
Sbjct: 432 PTDQAAAGTDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVL 491
Query: 481 RLSIRSNTAEDKFVFCNGLVLHRLQCLRGFGEWLDSIKDFSLNLQSLNLDIQALACLSAL 540
RLSIRSNTAEDKFVFCNGLVLHRLQCLRGFGEWLDSIKDFSLNLQSLNLDIQALACLSAL
Sbjct: 492 RLSIRSNTAEDKFVFCNGLVLHRLQCLRGFGEWLDSIKDFSLNLQSLNLDIQALACLSAL 551
Query: 541 SMITERHGLKEPKRVEELCNKITSSLKDHQSKGQALEPTESKVLGALVELRKICTLGLQR 600
SMITERHGLKEPKRVEELCNKITSSLKDHQSKGQALEPTESKVLGALVELRKICTLGLQR
Sbjct: 552 SMITERHGLKEPKRVEELCNKITSSLKDHQSKGQALEPTESKVLGALVELRKICTLGLQR 611
Query: 601 IFYLKLEDLVSPPSIIDKLFLDTLPF 626
IFYLKLEDLVSPPSIIDKLFLDTLPF
Sbjct: 612 IFYLKLEDLVSPPSIIDKLFLDTLPF 637
>gi|27894357 nuclear receptor subfamily 4, group A, member 3 isoform
a [Homo sapiens]
Length = 626
Score = 1290 bits (3337), Expect = 0.0
Identities = 626/626 (100%), Positives = 626/626 (100%)
Query: 1 MPCVQAQYSPSPPGSSYAAQTYSSEYTTEIMNPDYTKLTMDLGSTEITATATTSLPSIST 60
MPCVQAQYSPSPPGSSYAAQTYSSEYTTEIMNPDYTKLTMDLGSTEITATATTSLPSIST
Sbjct: 1 MPCVQAQYSPSPPGSSYAAQTYSSEYTTEIMNPDYTKLTMDLGSTEITATATTSLPSIST 60
Query: 61 FVEGYSSNYELKPSCVYQMQRPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQHQQPSIPPA 120
FVEGYSSNYELKPSCVYQMQRPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQHQQPSIPPA
Sbjct: 61 FVEGYSSNYELKPSCVYQMQRPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQHQQPSIPPA 120
Query: 121 SSPEDEVLPSTSMYFKQSPPSTPTTPAFPPQAGALWDEALPSAPGCIAPGPLLDPPMKAV 180
SSPEDEVLPSTSMYFKQSPPSTPTTPAFPPQAGALWDEALPSAPGCIAPGPLLDPPMKAV
Sbjct: 121 SSPEDEVLPSTSMYFKQSPPSTPTTPAFPPQAGALWDEALPSAPGCIAPGPLLDPPMKAV 180
Query: 181 PTVAGARFPLFHFKPSPPHPPAPSPAGGHHLGYDPTAAAALSLPLGAAAAAGSQAAALES 240
PTVAGARFPLFHFKPSPPHPPAPSPAGGHHLGYDPTAAAALSLPLGAAAAAGSQAAALES
Sbjct: 181 PTVAGARFPLFHFKPSPPHPPAPSPAGGHHLGYDPTAAAALSLPLGAAAAAGSQAAALES 240
Query: 241 HPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAA 300
HPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAA
Sbjct: 241 HPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAA 300
Query: 301 CQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKE 360
CQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKE
Sbjct: 301 CQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKE 360
Query: 361 VVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRALTDSTPRDLDYSRYC 420
VVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRALTDSTPRDLDYSRYC
Sbjct: 361 VVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRALTDSTPRDLDYSRYC 420
Query: 421 PTDQAAAGTDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVL 480
PTDQAAAGTDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVL
Sbjct: 421 PTDQAAAGTDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVL 480
Query: 481 RLSIRSNTAEDKFVFCNGLVLHRLQCLRGFGEWLDSIKDFSLNLQSLNLDIQALACLSAL 540
RLSIRSNTAEDKFVFCNGLVLHRLQCLRGFGEWLDSIKDFSLNLQSLNLDIQALACLSAL
Sbjct: 481 RLSIRSNTAEDKFVFCNGLVLHRLQCLRGFGEWLDSIKDFSLNLQSLNLDIQALACLSAL 540
Query: 541 SMITERHGLKEPKRVEELCNKITSSLKDHQSKGQALEPTESKVLGALVELRKICTLGLQR 600
SMITERHGLKEPKRVEELCNKITSSLKDHQSKGQALEPTESKVLGALVELRKICTLGLQR
Sbjct: 541 SMITERHGLKEPKRVEELCNKITSSLKDHQSKGQALEPTESKVLGALVELRKICTLGLQR 600
Query: 601 IFYLKLEDLVSPPSIIDKLFLDTLPF 626
IFYLKLEDLVSPPSIIDKLFLDTLPF
Sbjct: 601 IFYLKLEDLVSPPSIIDKLFLDTLPF 626
>gi|27894355 nuclear receptor subfamily 4, group A, member 3 isoform
a [Homo sapiens]
Length = 626
Score = 1290 bits (3337), Expect = 0.0
Identities = 626/626 (100%), Positives = 626/626 (100%)
Query: 1 MPCVQAQYSPSPPGSSYAAQTYSSEYTTEIMNPDYTKLTMDLGSTEITATATTSLPSIST 60
MPCVQAQYSPSPPGSSYAAQTYSSEYTTEIMNPDYTKLTMDLGSTEITATATTSLPSIST
Sbjct: 1 MPCVQAQYSPSPPGSSYAAQTYSSEYTTEIMNPDYTKLTMDLGSTEITATATTSLPSIST 60
Query: 61 FVEGYSSNYELKPSCVYQMQRPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQHQQPSIPPA 120
FVEGYSSNYELKPSCVYQMQRPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQHQQPSIPPA
Sbjct: 61 FVEGYSSNYELKPSCVYQMQRPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQHQQPSIPPA 120
Query: 121 SSPEDEVLPSTSMYFKQSPPSTPTTPAFPPQAGALWDEALPSAPGCIAPGPLLDPPMKAV 180
SSPEDEVLPSTSMYFKQSPPSTPTTPAFPPQAGALWDEALPSAPGCIAPGPLLDPPMKAV
Sbjct: 121 SSPEDEVLPSTSMYFKQSPPSTPTTPAFPPQAGALWDEALPSAPGCIAPGPLLDPPMKAV 180
Query: 181 PTVAGARFPLFHFKPSPPHPPAPSPAGGHHLGYDPTAAAALSLPLGAAAAAGSQAAALES 240
PTVAGARFPLFHFKPSPPHPPAPSPAGGHHLGYDPTAAAALSLPLGAAAAAGSQAAALES
Sbjct: 181 PTVAGARFPLFHFKPSPPHPPAPSPAGGHHLGYDPTAAAALSLPLGAAAAAGSQAAALES 240
Query: 241 HPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAA 300
HPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAA
Sbjct: 241 HPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAA 300
Query: 301 CQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKE 360
CQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKE
Sbjct: 301 CQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKE 360
Query: 361 VVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRALTDSTPRDLDYSRYC 420
VVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRALTDSTPRDLDYSRYC
Sbjct: 361 VVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRALTDSTPRDLDYSRYC 420
Query: 421 PTDQAAAGTDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVL 480
PTDQAAAGTDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVL
Sbjct: 421 PTDQAAAGTDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVL 480
Query: 481 RLSIRSNTAEDKFVFCNGLVLHRLQCLRGFGEWLDSIKDFSLNLQSLNLDIQALACLSAL 540
RLSIRSNTAEDKFVFCNGLVLHRLQCLRGFGEWLDSIKDFSLNLQSLNLDIQALACLSAL
Sbjct: 481 RLSIRSNTAEDKFVFCNGLVLHRLQCLRGFGEWLDSIKDFSLNLQSLNLDIQALACLSAL 540
Query: 541 SMITERHGLKEPKRVEELCNKITSSLKDHQSKGQALEPTESKVLGALVELRKICTLGLQR 600
SMITERHGLKEPKRVEELCNKITSSLKDHQSKGQALEPTESKVLGALVELRKICTLGLQR
Sbjct: 541 SMITERHGLKEPKRVEELCNKITSSLKDHQSKGQALEPTESKVLGALVELRKICTLGLQR 600
Query: 601 IFYLKLEDLVSPPSIIDKLFLDTLPF 626
IFYLKLEDLVSPPSIIDKLFLDTLPF
Sbjct: 601 IFYLKLEDLVSPPSIIDKLFLDTLPF 626
>gi|27894359 nuclear receptor subfamily 4, group A, member 3 isoform
c [Homo sapiens]
Length = 443
Score = 880 bits (2275), Expect = 0.0
Identities = 418/418 (100%), Positives = 418/418 (100%)
Query: 1 MPCVQAQYSPSPPGSSYAAQTYSSEYTTEIMNPDYTKLTMDLGSTEITATATTSLPSIST 60
MPCVQAQYSPSPPGSSYAAQTYSSEYTTEIMNPDYTKLTMDLGSTEITATATTSLPSIST
Sbjct: 1 MPCVQAQYSPSPPGSSYAAQTYSSEYTTEIMNPDYTKLTMDLGSTEITATATTSLPSIST 60
Query: 61 FVEGYSSNYELKPSCVYQMQRPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQHQQPSIPPA 120
FVEGYSSNYELKPSCVYQMQRPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQHQQPSIPPA
Sbjct: 61 FVEGYSSNYELKPSCVYQMQRPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQHQQPSIPPA 120
Query: 121 SSPEDEVLPSTSMYFKQSPPSTPTTPAFPPQAGALWDEALPSAPGCIAPGPLLDPPMKAV 180
SSPEDEVLPSTSMYFKQSPPSTPTTPAFPPQAGALWDEALPSAPGCIAPGPLLDPPMKAV
Sbjct: 121 SSPEDEVLPSTSMYFKQSPPSTPTTPAFPPQAGALWDEALPSAPGCIAPGPLLDPPMKAV 180
Query: 181 PTVAGARFPLFHFKPSPPHPPAPSPAGGHHLGYDPTAAAALSLPLGAAAAAGSQAAALES 240
PTVAGARFPLFHFKPSPPHPPAPSPAGGHHLGYDPTAAAALSLPLGAAAAAGSQAAALES
Sbjct: 181 PTVAGARFPLFHFKPSPPHPPAPSPAGGHHLGYDPTAAAALSLPLGAAAAAGSQAAALES 240
Query: 241 HPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAA 300
HPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAA
Sbjct: 241 HPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAA 300
Query: 301 CQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKE 360
CQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKE
Sbjct: 301 CQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKE 360
Query: 361 VVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRALTDSTPRDLDYSR 418
VVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRALTDSTPRDLDYSR
Sbjct: 361 VVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRALTDSTPRDLDYSR 418
>gi|5453822 nuclear receptor subfamily 4, group A, member 2 [Homo
sapiens]
Length = 598
Score = 652 bits (1683), Expect = 0.0
Identities = 366/653 (56%), Positives = 440/653 (67%), Gaps = 82/653 (12%)
Query: 1 MPCVQAQYSPSPPGSSYAAQTYS----SEYTTEIMNPDYTKLTMDLGSTEITATATTSLP 56
MPCVQAQY SP G+S A+Q+YS EY+++ + P++ K +MDL +TEITAT TSLP
Sbjct: 1 MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITAT--TSLP 58
Query: 57 SISTFVEGYSSNYELKPSCVYQM----QRPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQH 112
S STF++ YS+ Y++KP C+YQM Q+ IKVE+ + +Y H H
Sbjct: 59 SFSTFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSH------------- 105
Query: 113 QQPSIPPASSPEDEVLP-STSMYFKQSPPSTPTTPAFPPQAGALWDEALPSAPGCIAPGP 171
+PP S +E++P S S+Y+K S P TPTTP F Q +WD+ PG
Sbjct: 106 ----LPPQS---EEMMPHSGSVYYKPSSPPTPTTPGFQVQHSPMWDD----------PGS 148
Query: 172 LLDPPMKAVPTV--------AGARFPLFHFKPSPPHPPAPSPA----GGHHLGYDPTAAA 219
L + V T +R LF FK SPP P S G H+ +P
Sbjct: 149 LHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNPE--- 205
Query: 220 ALSLPLGAAAAAGSQAAALESHPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPS 279
P G+ Q A+ + P+ K A+ + FP L + AS LL +PS
Sbjct: 206 ----PAGSHHVVDGQTFAVPN-----PIRKPAS-MGFPGLQIGH---ASQLL--DTQVPS 250
Query: 280 PPSRSSSSGEGTCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKR 339
PPSR S S EG CAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKR
Sbjct: 251 PPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKR 310
Query: 340 RRNRCQYCRFQKCLSVGMVKEVVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMM 399
RRNRCQYCRFQKCL+VGMVKEVVRTDSLKGRRGRLPSKPKS P +PSPPSPP+ ++
Sbjct: 311 RRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKS-----PQEPSPPSPPVSLI 365
Query: 400 NALVRALTDSTP--RDLDYSRY-CPTDQAAAGTDAEHVQQFYNLLTASIDVSRSWAEKIP 456
+ALVRA DS P LDYSR+ D +G D +H+QQFY+LLT S+++ R WAEKIP
Sbjct: 366 SALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIP 425
Query: 457 GFTDLPKEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCNGLVLHRLQCLRGFGEWLDS 516
GF DLPK DQ LL ESAFLELFVLRL+ RSN E K +FCNG+VLHRLQC+RGFGEW+DS
Sbjct: 426 GFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDS 485
Query: 517 IKDFSLNLQSLNLDIQALACLSALSMITERHGLKEPKRVEELCNKITSSLKDHQ--SKGQ 574
I +FS NLQ++N+DI A +C++AL+M+TERHGLKEPKRVEEL NKI + LKDH + G
Sbjct: 486 IVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGG 545
Query: 575 ALEPTE-SKVLGALVELRKICTLGLQRIFYLKLEDLVSPPSIIDKLFLDTLPF 626
P SK+LG L ELR +CT GLQRIFYLKLEDLV PP+IIDKLFLDTLPF
Sbjct: 546 LNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF 598
>gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Homo
sapiens]
Length = 598
Score = 509 bits (1310), Expect = e-144
Identities = 312/648 (48%), Positives = 391/648 (60%), Gaps = 72/648 (11%)
Query: 1 MPCVQAQY---SPSPPGSSYAAQTYSSEYTTEIMNPDYTKLTMDLGSTEITATATTSLPS 57
MPC+QAQY +PSP + A ++ + P++ K TMDL S E A T+LPS
Sbjct: 1 MPCIQAQYGTPAPSPGPRDHLA--------SDPLTPEFIKPTMDLASPEAAPAAPTALPS 52
Query: 58 ISTFVEGYSSNYELKPSCVYQMQ---RPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQHQQ 114
STF++GY+ ++ + +YQ+ +P + + +
Sbjct: 53 FSTFMDGYTGEFD---TFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVY 109
Query: 115 PSIP-PASSPEDEVLPSTSMYFKQSPPS--TPTTPAFPPQAGALWDEALPSAPGCIAPGP 171
P P S P DE L S+ + SP S +P+TP+F P + WD + G +P
Sbjct: 110 GCYPGPLSGPVDEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSF----GHFSPSQ 165
Query: 172 L---LDPPMKAVPTVAGARFPLFHFKPSPPHPPAPSPAGGHHLGYDPTAAAALSL-PLGA 227
L + +P +G P F SPP P+PS A + L L P A
Sbjct: 166 TYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPS-----------LAQSPLKLFPSQA 214
Query: 228 AAAAGSQAAALESHPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSS 287
G E Y +P A FP L T S + ++P + S +RS +
Sbjct: 215 THQLG------EGESYSMPTA-------FPGLAPTSPHLEGSGILDTP-VTSTKARSGAP 260
Query: 288 G--EGTCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQ 345
G EG CAVCGDNA+CQHYGVRTCEGCKGFFKRTVQKNAKY+CLANK+CPVDKRRRNRCQ
Sbjct: 261 GGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQ 320
Query: 346 YCRFQKCLSVGMVKEVVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRA 405
+CRFQKCL+VGMVKEVVRTDSLKGRRGRLPSKPK P P + P ++ +LVRA
Sbjct: 321 FCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQP---------PDASPANLLTSLVRA 371
Query: 406 LTDSTP--RDLDYSRYCPTDQAAAG-TDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLP 462
DS P LDYS++ G DA VQQFY+LL+ S++V R WAEKIPGF +L
Sbjct: 372 HLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELS 431
Query: 463 KEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCNGLVLHRLQCLRGFGEWLDSIKDFSL 522
DQ LL+ESAFLELF+LRL+ RS E K +FC+GLVLHRLQC RGFG+W+DSI FS
Sbjct: 432 PADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSR 491
Query: 523 NLQSLNLDIQALACLSALSMITERHGLKEPKRVEELCNKITSSLKDHQSKGQALEPTE-- 580
+L SL +D+ A ACLSAL +IT+RHGL+EP+RVEEL N+I S LK+H + A EP
Sbjct: 492 SLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVA-AVAGEPQPAS 550
Query: 581 --SKVLGALVELRKICTLGLQRIFYLKLEDLVSPPSIIDKLFLDTLPF 626
S++LG L ELR +CT GLQRIFYLKLEDLV PP IIDK+F+DTLPF
Sbjct: 551 CLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF 598
>gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Homo
sapiens]
Length = 598
Score = 509 bits (1310), Expect = e-144
Identities = 312/648 (48%), Positives = 391/648 (60%), Gaps = 72/648 (11%)
Query: 1 MPCVQAQY---SPSPPGSSYAAQTYSSEYTTEIMNPDYTKLTMDLGSTEITATATTSLPS 57
MPC+QAQY +PSP + A ++ + P++ K TMDL S E A T+LPS
Sbjct: 1 MPCIQAQYGTPAPSPGPRDHLA--------SDPLTPEFIKPTMDLASPEAAPAAPTALPS 52
Query: 58 ISTFVEGYSSNYELKPSCVYQMQ---RPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQHQQ 114
STF++GY+ ++ + +YQ+ +P + + +
Sbjct: 53 FSTFMDGYTGEFD---TFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVY 109
Query: 115 PSIP-PASSPEDEVLPSTSMYFKQSPPS--TPTTPAFPPQAGALWDEALPSAPGCIAPGP 171
P P S P DE L S+ + SP S +P+TP+F P + WD + G +P
Sbjct: 110 GCYPGPLSGPVDEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSF----GHFSPSQ 165
Query: 172 L---LDPPMKAVPTVAGARFPLFHFKPSPPHPPAPSPAGGHHLGYDPTAAAALSL-PLGA 227
L + +P +G P F SPP P+PS A + L L P A
Sbjct: 166 TYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPS-----------LAQSPLKLFPSQA 214
Query: 228 AAAAGSQAAALESHPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSS 287
G E Y +P A FP L T S + ++P + S +RS +
Sbjct: 215 THQLG------EGESYSMPTA-------FPGLAPTSPHLEGSGILDTP-VTSTKARSGAP 260
Query: 288 G--EGTCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQ 345
G EG CAVCGDNA+CQHYGVRTCEGCKGFFKRTVQKNAKY+CLANK+CPVDKRRRNRCQ
Sbjct: 261 GGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQ 320
Query: 346 YCRFQKCLSVGMVKEVVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRA 405
+CRFQKCL+VGMVKEVVRTDSLKGRRGRLPSKPK P P + P ++ +LVRA
Sbjct: 321 FCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQP---------PDASPANLLTSLVRA 371
Query: 406 LTDSTP--RDLDYSRYCPTDQAAAG-TDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLP 462
DS P LDYS++ G DA VQQFY+LL+ S++V R WAEKIPGF +L
Sbjct: 372 HLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELS 431
Query: 463 KEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCNGLVLHRLQCLRGFGEWLDSIKDFSL 522
DQ LL+ESAFLELF+LRL+ RS E K +FC+GLVLHRLQC RGFG+W+DSI FS
Sbjct: 432 PADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSR 491
Query: 523 NLQSLNLDIQALACLSALSMITERHGLKEPKRVEELCNKITSSLKDHQSKGQALEPTE-- 580
+L SL +D+ A ACLSAL +IT+RHGL+EP+RVEEL N+I S LK+H + A EP
Sbjct: 492 SLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVA-AVAGEPQPAS 550
Query: 581 --SKVLGALVELRKICTLGLQRIFYLKLEDLVSPPSIIDKLFLDTLPF 626
S++LG L ELR +CT GLQRIFYLKLEDLV PP IIDK+F+DTLPF
Sbjct: 551 CLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF 598
>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 197 bits (501), Expect = 2e-50
Identities = 146/435 (33%), Positives = 214/435 (49%), Gaps = 33/435 (7%)
Query: 203 PSPAGGHHLGYDPTAAAALSLP--LGAAAAAGSQAAALESHPYGLPLAKRAAPLAFPPLG 260
P+P GGH GY P A P LG + G AL + + LP++ + P P
Sbjct: 9 PTPGGGHLNGY-PVPPYAFFFPPMLGGLSPPG----ALTTLQHQLPVSGYSTP---SPAT 60
Query: 261 LTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAACQHYGVRTCEGCKGFFKRTV 320
+ ++S + SP P P R C VC D ++ HYGV CEGCKGFF+R++
Sbjct: 61 IETQSSSSEEIVPSPPSPPPLPRIYKP----CFVCQDKSSGYHYGVSACEGCKGFFRRSI 116
Query: 321 QKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRTDSLKGRRGRLPSKPKS 380
QKN Y C +KNC ++K RNRCQYCR QKC VGM KE VR D K K K
Sbjct: 117 QKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNK--------KKKE 168
Query: 381 PLQQEPSQPSPPSPPICMMNALVR-ALTDSTPRDLDYSRYCP--TDQAAAGTDAEHVQQF 437
+ E S+ +P + + VR A ++ P +Y + + D + +F
Sbjct: 169 VPKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKF 228
Query: 438 YNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCN 497
L T I + +A+++PGFT L DQ L+++A L++ +LR+ R +D F +
Sbjct: 229 SELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSD 288
Query: 498 GLVLHRLQCLR-GFGEWLDSIKDFSLNLQSLNLDIQALACLSALSMIT-ERHGLKEPKRV 555
GL L+R Q GFG D + F+ L L +D LSA+ +I +R L++P RV
Sbjct: 289 GLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRV 348
Query: 556 EELCNKITSSLKDHQSKGQALEP-TESKVLGALVELRKICTLGLQRIFYLKLEDLVSPPS 614
+ L + +LK + K + P K+L + +LR I G +R+ LK+E S P
Sbjct: 349 DMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPP 408
Query: 615 IIDKLF-----LDTL 624
+I ++ LDTL
Sbjct: 409 LIQEMLENSEGLDTL 423
>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 197 bits (501), Expect = 2e-50
Identities = 146/435 (33%), Positives = 214/435 (49%), Gaps = 33/435 (7%)
Query: 203 PSPAGGHHLGYDPTAAAALSLP--LGAAAAAGSQAAALESHPYGLPLAKRAAPLAFPPLG 260
P+P GGH GY P A P LG + G AL + + LP++ + P P
Sbjct: 9 PTPGGGHLNGY-PVPPYAFFFPPMLGGLSPPG----ALTTLQHQLPVSGYSTP---SPAT 60
Query: 261 LTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAACQHYGVRTCEGCKGFFKRTV 320
+ ++S + SP P P R C VC D ++ HYGV CEGCKGFF+R++
Sbjct: 61 IETQSSSSEEIVPSPPSPPPLPRIYKP----CFVCQDKSSGYHYGVSACEGCKGFFRRSI 116
Query: 321 QKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRTDSLKGRRGRLPSKPKS 380
QKN Y C +KNC ++K RNRCQYCR QKC VGM KE VR D K K K
Sbjct: 117 QKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNK--------KKKE 168
Query: 381 PLQQEPSQPSPPSPPICMMNALVR-ALTDSTPRDLDYSRYCP--TDQAAAGTDAEHVQQF 437
+ E S+ +P + + VR A ++ P +Y + + D + +F
Sbjct: 169 VPKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKF 228
Query: 438 YNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCN 497
L T I + +A+++PGFT L DQ L+++A L++ +LR+ R +D F +
Sbjct: 229 SELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSD 288
Query: 498 GLVLHRLQCLR-GFGEWLDSIKDFSLNLQSLNLDIQALACLSALSMIT-ERHGLKEPKRV 555
GL L+R Q GFG D + F+ L L +D LSA+ +I +R L++P RV
Sbjct: 289 GLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRV 348
Query: 556 EELCNKITSSLKDHQSKGQALEP-TESKVLGALVELRKICTLGLQRIFYLKLEDLVSPPS 614
+ L + +LK + K + P K+L + +LR I G +R+ LK+E S P
Sbjct: 349 DMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPP 408
Query: 615 IIDKLF-----LDTL 624
+I ++ LDTL
Sbjct: 409 LIQEMLENSEGLDTL 423
>gi|11415052 retinoid X receptor, beta [Homo sapiens]
Length = 533
Score = 188 bits (478), Expect = 1e-47
Identities = 139/473 (29%), Positives = 211/473 (44%), Gaps = 61/473 (12%)
Query: 139 PPSTPTTPAFPPQAGALWDEALPSAPGCIAPGPLLDPPMKAVPTVAGARFPLFHFKPSPP 198
PP +P P PP PS G AP P PPM P G+ FP+ P
Sbjct: 96 PPPSPPGPPLPPSTA-------PSLGGSGAPPP---PPMPPPPL--GSPFPVISSSMGSP 143
Query: 199 HPPAPSPAGGHHLGYDPTAAAALSLPLGAAAAAGSQAAALESHPYGLPLAKRAAPLAFPP 258
P P+P G P + +SLP G + PP
Sbjct: 144 GLPPPAPPGFSGPVSSPQINSTVSLPGGGSG---------------------------PP 176
Query: 259 LGLTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAACQHYGVRTCEGCKGFFKR 318
+ P +LG PP +G+ CA+CGD ++ +HYGV +CEGCKGFFKR
Sbjct: 177 EDVKPP-----VLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKR 231
Query: 319 TVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRTDSLKGRRGRLPSKP 378
T++K+ Y C NK+C VDKR+RNRCQYCR+QKCL+ GM +E V+ + +G+
Sbjct: 232 TIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGK-------- 283
Query: 379 KSPLQQEPSQPSPPSPPICMMNALVRALTDSTPRDLDYSRYCPTDQAAAGTDA-EHVQQF 437
E + +P P+ + A+ + + ++ P +G+ + V
Sbjct: 284 DKDGDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVE----GPGGTGGSGSSPNDPVTNI 339
Query: 438 YNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCN 497
+ WA++IP F+ LP +DQ +L+ + + EL + S RS D +
Sbjct: 340 CQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLAT 399
Query: 498 GLVLHRLQC-LRGFGEWLDSI-KDFSLNLQSLNLDIQALACLSALSMIT-ERHGLKEPKR 554
GL +HR G G D + + ++ + +D L CL A+ + + GL P
Sbjct: 400 GLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSE 459
Query: 555 VEELCNKITSSLKDH-QSKGQALEPTESKVLGALVELRKICTLGLQRIFYLKL 606
VE L K+ +SL+ + + K + +K+L L LR I L+ +F+ KL
Sbjct: 460 VEVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKL 512
>gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens]
Length = 448
Score = 188 bits (478), Expect = 1e-47
Identities = 124/365 (33%), Positives = 183/365 (50%), Gaps = 28/365 (7%)
Query: 266 TASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAK 325
T+S L SP P PP R C VC D ++ HYGV CEGCKGFF+R++QKN
Sbjct: 59 TSSEELVPSPPSPLPPPRVYKP----CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMI 114
Query: 326 YVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRTDSLKGRRGRLPSKPKSPLQQE 385
Y C +KNC ++K RNRCQYCR QKC VGM KE VR D K K K +QE
Sbjct: 115 YTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNK--------KKKETSKQE 166
Query: 386 PSQPSPPSPPICMMNALVRALTDSTPRDLDYSRYCPTDQAAAGTDAEH--------VQQF 437
++ + + + +R T + C + + A+H +F
Sbjct: 167 CTESYEMTAELDDLTEKIRKAHQET-----FPSLCQLGKYTTNSSADHRVRLDLGLWDKF 221
Query: 438 YNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCN 497
L T I +A+++PGFT L DQ L+++A L++ +LR+ R +D F +
Sbjct: 222 SELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSD 281
Query: 498 GLVLHRLQCLR-GFGEWLDSIKDFSLNLQSLNLDIQALACLSALSMIT-ERHGLKEPKRV 555
GL L+R Q GFG D + F+ L L +D LSA+ +I +R L+EP +V
Sbjct: 282 GLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKV 341
Query: 556 EELCNKITSSLKDHQSKGQALEP-TESKVLGALVELRKICTLGLQRIFYLKLEDLVSPPS 614
++L + +LK + K + +P K+L + +LR I G +R+ LK+E S P
Sbjct: 342 DKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPP 401
Query: 615 IIDKL 619
+I ++
Sbjct: 402 LIQEM 406
>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
Length = 443
Score = 187 bits (474), Expect = 3e-47
Identities = 130/402 (32%), Positives = 199/402 (49%), Gaps = 37/402 (9%)
Query: 229 AAAGSQAAALESHPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSSG 288
A GS A LES + P + ++ T S ++ ++ SPS P PP
Sbjct: 29 ATGGSCFAGLESFAWPQPASLQSVE--------TQSTSSEEMVPSSPSPPPPPRVYKP-- 78
Query: 289 EGTCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCR 348
C VC D ++ HYGV +CEGCKGFF+R++QKN Y C +KNC ++K RNRCQYCR
Sbjct: 79 ---CFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCR 135
Query: 349 FQKCLSVGMVKEVVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRALTD 408
QKC VGM KE VR D +K K +++E S S P + L+ +
Sbjct: 136 LQKCFEVGMSKEAVRNDR---------NKKKKEVKEEGSPDSYELSP--QLEELITKV-- 182
Query: 409 STPRDLDYSRYCPTDQAAAGTDAEHVQQ--------FYNLLTASIDVSRSWAEKIPGFTD 460
S + C + + A+H Q F L T I +A+++PGFT
Sbjct: 183 SKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTG 242
Query: 461 LPKEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCNGLVLHRLQCLR-GFGEWLDSIKD 519
L DQ L+++A L++ +LR+ R +D F +GL L+R Q GFG D +
Sbjct: 243 LSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFA 302
Query: 520 FSLNLQSLNLDIQALACLSALSMIT-ERHGLKEPKRVEELCNKITSSLKDHQSKGQALEP 578
F+ L L +D LSA+ +I +R L+EP++V++L + +L+ + + + +P
Sbjct: 303 FAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQP 362
Query: 579 -TESKVLGALVELRKICTLGLQRIFYLKLEDLVSPPSIIDKL 619
++L + +LR I T G +R LK+E P +I ++
Sbjct: 363 YMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREM 404
>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
Length = 457
Score = 185 bits (469), Expect = 1e-46
Identities = 127/361 (35%), Positives = 184/361 (50%), Gaps = 21/361 (5%)
Query: 275 PSLPSPPSRSSSSGEGTCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNC 334
PS PSPP C VC D ++ HYGV CEGCKGFF+R++QKN Y C +KNC
Sbjct: 68 PSPPSPPPLPRIYKP--CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNC 125
Query: 335 PVDKRRRNRCQYCRFQKCLSVGMVKEVVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSP 394
++K RNRCQYCR QKC VGM KE VR D K K K + E S+ +P
Sbjct: 126 IINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNK--------KKKEVPKPECSESYTLTP 177
Query: 395 PICMMNALVR-ALTDSTPRDLDYSRYCP--TDQAAAGTDAEHVQQFYNLLTASIDVSRSW 451
+ + VR A ++ P +Y + + D + +F L T I + +
Sbjct: 178 EVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEF 237
Query: 452 AEKIPGFTDLPKEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCNGLVLHRLQCLR-GF 510
A+++PGFT L DQ L+++A L++ +LR+ R +D F +GL L+R Q GF
Sbjct: 238 AKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGF 297
Query: 511 GEWLDSIKDFSLNLQSLNLDIQALACLSALSMIT-ERHGLKEPKRVEELCNKITSSLKDH 569
G D + F+ L L +D LSA+ +I +R L++P RV+ L + +LK +
Sbjct: 298 GPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVY 357
Query: 570 QSKGQALEP-TESKVLGALVELRKICTLGLQRIFYLKLEDLVSPPSIIDKLF-----LDT 623
K + P K+L + +LR I G +R+ LK+E S P +I ++ LDT
Sbjct: 358 VRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGLDT 417
Query: 624 L 624
L
Sbjct: 418 L 418
>gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]
Length = 454
Score = 183 bits (465), Expect = 4e-46
Identities = 122/369 (33%), Positives = 187/369 (50%), Gaps = 29/369 (7%)
Query: 262 TPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAACQHYGVRTCEGCKGFFKRTVQ 321
T S ++ ++ SPS P PP C VC D ++ HYGV +CEGCKGFF+R++Q
Sbjct: 65 TQSTSSEEMVPSSPSPPPPPRVYKP-----CFVCNDKSSGYHYGVSSCEGCKGFFRRSIQ 119
Query: 322 KNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRTDSLKGRRGRLPSKPKSP 381
KN Y C +KNC ++K RNRCQYCR QKC VGM KE VR D +K K
Sbjct: 120 KNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDR---------NKKKKE 170
Query: 382 LQQEPSQPSPPSPPICMMNALVRALTDSTPRDLDYSRYCPTDQAAAGTDAEHVQQ----- 436
+++E S S P + L+ + S + C + + A+H Q
Sbjct: 171 VKEEGSPDSYELSP--QLEELITKV--SKAHQETFPSLCQLGKYTTNSSADHRVQLDLGL 226
Query: 437 ---FYNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVLRLSIRSNTAEDKF 493
F L T I +A+++PGFT L DQ L+++A L++ +LR+ R +D
Sbjct: 227 WDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTM 286
Query: 494 VFCNGLVLHRLQCLR-GFGEWLDSIKDFSLNLQSLNLDIQALACLSALSMIT-ERHGLKE 551
F +GL L+R Q GFG D + F+ L L +D LSA+ +I +R L+E
Sbjct: 287 TFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEE 346
Query: 552 PKRVEELCNKITSSLKDHQSKGQALEP-TESKVLGALVELRKICTLGLQRIFYLKLEDLV 610
P++V++L + +L+ + + + +P ++L + +LR I T G +R LK+E
Sbjct: 347 PEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPG 406
Query: 611 SPPSIIDKL 619
P +I ++
Sbjct: 407 PMPPLIREM 415
>gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
Length = 463
Score = 179 bits (454), Expect = 7e-45
Identities = 127/427 (29%), Positives = 200/427 (46%), Gaps = 35/427 (8%)
Query: 194 KPSPPHPP-APSPAGGHHLGYDPTAAAALSLPLGAAAAAGSQAAALESHPYGLPLAKRAA 252
KP HP +P P +A+ PL A + + P G A
Sbjct: 37 KPMDSHPSYTDTPVSA------PRTLSAVGTPLNALGSPYRVITSAMGPPSGALAAPPGI 90
Query: 253 PLAFPP---LGLTPSPTASSLLGESPSLPS------PPSRSSSSGEGTCAVCGDNAACQH 303
L PP L + S ++S + P LP P + S + CA+CGD ++ +H
Sbjct: 91 NLVAPPSSQLNVVNSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKH 150
Query: 304 YGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVR 363
YGV +CEGCKGFFKRT++K+ Y C NK+C +DKR+RNRCQYCR+QKCL +GM +E V+
Sbjct: 151 YGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQ 210
Query: 364 TDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRALTDSTPRDLDYSRYCPTD 423
+ R S+ ++ + E + P+ + A+ T D + T+
Sbjct: 211 EE-------RQRSRERAESEAECATSGHEDMPVERILEAELAVEPKTESYGDMNMENSTN 263
Query: 424 QAAAGTDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVLRLS 483
+Q + L+ WA++IP F+DL EDQ +L+ + + EL + S
Sbjct: 264 DPVTNICHAADKQLFTLV--------EWAKRIPHFSDLTLEDQVILLRAGWNELLIASFS 315
Query: 484 IRSNTAEDKFVFCNGLVLHRLQC-LRGFGEWLDSI-KDFSLNLQSLNLDIQALACLSALS 541
RS + +D + GL +HR G G D + + ++ + +D L CL A+
Sbjct: 316 HRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIV 375
Query: 542 MIT-ERHGLKEPKRVEELCNKITSSLKDHQSKGQALEPTE-SKVLGALVELRKICTLGLQ 599
+ + GL P VE L K+ ++L+ + + +P +K+L L LR I L+
Sbjct: 376 LFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLE 435
Query: 600 RIFYLKL 606
+F+ KL
Sbjct: 436 HLFFFKL 442
>gi|45545429 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 174 bits (441), Expect = 2e-43
Identities = 136/445 (30%), Positives = 212/445 (47%), Gaps = 44/445 (9%)
Query: 194 KPSPPHPPAPSPAGGHHLGYDPTAAAALSLPLGAAAAAGSQAAALESHPYGL---PLAKR 250
K P P + + + HH P G++ A+GS ++ + H GL PL
Sbjct: 17 KTEPSSPASLTDSVNHHS------------PGGSSDASGSYSSTMNGHQNGLDSPPLYPS 64
Query: 251 AAPLAFPPLGLTPSPTASSLLGESPS------LPSPPSRSSSSGEGTCAVCGDNAACQHY 304
A L SS + E P L S P R C VCGD A+ HY
Sbjct: 65 APILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKR-------LCLVCGDIASGYHY 117
Query: 305 GVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRT 364
GV +CE CK FFKRT+Q N +Y C A C + KRRR CQ CRF KCL VGM+KE VR
Sbjct: 118 GVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRL 177
Query: 365 DSLKGRRGRLPSKPKSPLQQEP-SQPSPPSPPICMMNALVRALTDSTPRDLDYSRYCPTD 423
D ++G GR K + + P P P N +V L + P + Y D
Sbjct: 178 DRVRG--GRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKI----YAMPD 231
Query: 424 QAAAGTDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVLRLS 483
+D + + +L + V WA+ IPGF+ L DQ L++SA++E+ +L +
Sbjct: 232 PTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVV 291
Query: 484 IRSNTAEDKFVFCNGLVLHRLQC-LRGFGEWLDSIKDFSLNLQSLNLDIQALACLSALSM 542
RS + ED+ V+ + ++ Q L G + ++I +S+ L+ + L A+++
Sbjct: 292 YRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIAL 351
Query: 543 I-TERHGLKEPKRVEELCNKITSSLKDHQSKGQALEPTE--SKVLGALVELRKICTLGLQ 599
++ +++ + V++L + + +L+D+++ GQ +E K+L L LR+ T +Q
Sbjct: 352 ANSDSMHIEDVEAVQKLQDVLHEALQDYEA-GQHMEDPRRAGKMLMTLPLLRQTSTKAVQ 410
Query: 600 RIFYLKLEDLVSPPSIIDKLFLDTL 624
+ +KLE V + KLFL+ L
Sbjct: 411 HFYNIKLEGKVP----MHKLFLEML 431
>gi|45545427 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 174 bits (441), Expect = 2e-43
Identities = 136/445 (30%), Positives = 212/445 (47%), Gaps = 44/445 (9%)
Query: 194 KPSPPHPPAPSPAGGHHLGYDPTAAAALSLPLGAAAAAGSQAAALESHPYGL---PLAKR 250
K P P + + + HH P G++ A+GS ++ + H GL PL
Sbjct: 17 KTEPSSPASLTDSVNHHS------------PGGSSDASGSYSSTMNGHQNGLDSPPLYPS 64
Query: 251 AAPLAFPPLGLTPSPTASSLLGESPS------LPSPPSRSSSSGEGTCAVCGDNAACQHY 304
A L SS + E P L S P R C VCGD A+ HY
Sbjct: 65 APILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKR-------LCLVCGDIASGYHY 117
Query: 305 GVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRT 364
GV +CE CK FFKRT+Q N +Y C A C + KRRR CQ CRF KCL VGM+KE VR
Sbjct: 118 GVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRL 177
Query: 365 DSLKGRRGRLPSKPKSPLQQEP-SQPSPPSPPICMMNALVRALTDSTPRDLDYSRYCPTD 423
D ++G GR K + + P P P N +V L + P + Y D
Sbjct: 178 DRVRG--GRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKI----YAMPD 231
Query: 424 QAAAGTDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVLRLS 483
+D + + +L + V WA+ IPGF+ L DQ L++SA++E+ +L +
Sbjct: 232 PTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVV 291
Query: 484 IRSNTAEDKFVFCNGLVLHRLQC-LRGFGEWLDSIKDFSLNLQSLNLDIQALACLSALSM 542
RS + ED+ V+ + ++ Q L G + ++I +S+ L+ + L A+++
Sbjct: 292 YRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIAL 351
Query: 543 I-TERHGLKEPKRVEELCNKITSSLKDHQSKGQALEPTE--SKVLGALVELRKICTLGLQ 599
++ +++ + V++L + + +L+D+++ GQ +E K+L L LR+ T +Q
Sbjct: 352 ANSDSMHIEDVEAVQKLQDVLHEALQDYEA-GQHMEDPRRAGKMLMTLPLLRQTSTKAVQ 410
Query: 600 RIFYLKLEDLVSPPSIIDKLFLDTL 624
+ +KLE V + KLFL+ L
Sbjct: 411 HFYNIKLEGKVP----MHKLFLEML 431
>gi|45545433 estrogen-related receptor gamma isoform 1 [Homo
sapiens]
Length = 458
Score = 174 bits (441), Expect = 2e-43
Identities = 136/445 (30%), Positives = 212/445 (47%), Gaps = 44/445 (9%)
Query: 194 KPSPPHPPAPSPAGGHHLGYDPTAAAALSLPLGAAAAAGSQAAALESHPYGL---PLAKR 250
K P P + + + HH P G++ A+GS ++ + H GL PL
Sbjct: 40 KTEPSSPASLTDSVNHHS------------PGGSSDASGSYSSTMNGHQNGLDSPPLYPS 87
Query: 251 AAPLAFPPLGLTPSPTASSLLGESPS------LPSPPSRSSSSGEGTCAVCGDNAACQHY 304
A L SS + E P L S P R C VCGD A+ HY
Sbjct: 88 APILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKR-------LCLVCGDIASGYHY 140
Query: 305 GVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRT 364
GV +CE CK FFKRT+Q N +Y C A C + KRRR CQ CRF KCL VGM+KE VR
Sbjct: 141 GVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRL 200
Query: 365 DSLKGRRGRLPSKPKSPLQQEP-SQPSPPSPPICMMNALVRALTDSTPRDLDYSRYCPTD 423
D ++G GR K + + P P P N +V L + P + Y D
Sbjct: 201 DRVRG--GRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKI----YAMPD 254
Query: 424 QAAAGTDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVLRLS 483
+D + + +L + V WA+ IPGF+ L DQ L++SA++E+ +L +
Sbjct: 255 PTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVV 314
Query: 484 IRSNTAEDKFVFCNGLVLHRLQC-LRGFGEWLDSIKDFSLNLQSLNLDIQALACLSALSM 542
RS + ED+ V+ + ++ Q L G + ++I +S+ L+ + L A+++
Sbjct: 315 YRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIAL 374
Query: 543 I-TERHGLKEPKRVEELCNKITSSLKDHQSKGQALEPTE--SKVLGALVELRKICTLGLQ 599
++ +++ + V++L + + +L+D+++ GQ +E K+L L LR+ T +Q
Sbjct: 375 ANSDSMHIEDVEAVQKLQDVLHEALQDYEA-GQHMEDPRRAGKMLMTLPLLRQTSTKAVQ 433
Query: 600 RIFYLKLEDLVSPPSIIDKLFLDTL 624
+ +KLE V + KLFL+ L
Sbjct: 434 HFYNIKLEGKVP----MHKLFLEML 454
>gi|197209821 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 174 bits (441), Expect = 2e-43
Identities = 136/445 (30%), Positives = 212/445 (47%), Gaps = 44/445 (9%)
Query: 194 KPSPPHPPAPSPAGGHHLGYDPTAAAALSLPLGAAAAAGSQAAALESHPYGL---PLAKR 250
K P P + + + HH P G++ A+GS ++ + H GL PL
Sbjct: 17 KTEPSSPASLTDSVNHHS------------PGGSSDASGSYSSTMNGHQNGLDSPPLYPS 64
Query: 251 AAPLAFPPLGLTPSPTASSLLGESPS------LPSPPSRSSSSGEGTCAVCGDNAACQHY 304
A L SS + E P L S P R C VCGD A+ HY
Sbjct: 65 APILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKR-------LCLVCGDIASGYHY 117
Query: 305 GVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRT 364
GV +CE CK FFKRT+Q N +Y C A C + KRRR CQ CRF KCL VGM+KE VR
Sbjct: 118 GVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRL 177
Query: 365 DSLKGRRGRLPSKPKSPLQQEP-SQPSPPSPPICMMNALVRALTDSTPRDLDYSRYCPTD 423
D ++G GR K + + P P P N +V L + P + Y D
Sbjct: 178 DRVRG--GRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKI----YAMPD 231
Query: 424 QAAAGTDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVLRLS 483
+D + + +L + V WA+ IPGF+ L DQ L++SA++E+ +L +
Sbjct: 232 PTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVV 291
Query: 484 IRSNTAEDKFVFCNGLVLHRLQC-LRGFGEWLDSIKDFSLNLQSLNLDIQALACLSALSM 542
RS + ED+ V+ + ++ Q L G + ++I +S+ L+ + L A+++
Sbjct: 292 YRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIAL 351
Query: 543 I-TERHGLKEPKRVEELCNKITSSLKDHQSKGQALEPTE--SKVLGALVELRKICTLGLQ 599
++ +++ + V++L + + +L+D+++ GQ +E K+L L LR+ T +Q
Sbjct: 352 ANSDSMHIEDVEAVQKLQDVLHEALQDYEA-GQHMEDPRRAGKMLMTLPLLRQTSTKAVQ 410
Query: 600 RIFYLKLEDLVSPPSIIDKLFLDTL 624
+ +KLE V + KLFL+ L
Sbjct: 411 HFYNIKLEGKVP----MHKLFLEML 431
>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
Length = 462
Score = 173 bits (439), Expect = 4e-43
Identities = 133/452 (29%), Positives = 208/452 (46%), Gaps = 58/452 (12%)
Query: 164 PGCIAPGPLLDPPMKAVPTVAGARFPLFHFKPSPPHPPAPSPAGGHHLGYDPTAAAALSL 223
PG +PG L P + G PP SP G H + T S
Sbjct: 39 PGIGSPGQLHSPISTLSSPINGM---------GPPFSVISSPMGPHSMSVPTTPTLGFS- 88
Query: 224 PLGAAAAAGSQAAALESHPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSR 283
GS + +P ++ PPLGL + +L +P+ PS
Sbjct: 89 -------TGSPQLSSPMNPVS------SSEDIKPPLGL------NGVL----KVPAHPSG 125
Query: 284 SSSS-GEGTCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRN 342
+ +S + CA+CGD ++ +HYGV +CEGCKGFFKRTV+K+ Y C NK+C +DKR+RN
Sbjct: 126 NMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRN 185
Query: 343 RCQYCRFQKCLSVGMVKEVVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNAL 402
RCQYCR+QKCL++GM +E V+ + +G K ++ + E + + P+ +
Sbjct: 186 RCQYCRYQKCLAMGMKREAVQEERQRG-------KDRNENEVESTSSANEDMPVERILEA 238
Query: 403 VRALTDSTPR----DLDYSRYCPTDQAAAGTDAEHVQQFYNLLTASIDVSRSWAEKIPGF 458
A+ T ++ + P D A Q F + WA++IP F
Sbjct: 239 ELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLV---------EWAKRIPHF 289
Query: 459 TDLPKEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCNGLVLHRLQC-LRGFGEWLDSI 517
++LP +DQ +L+ + + EL + S RS +D + GL +HR G G D +
Sbjct: 290 SELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRV 349
Query: 518 -KDFSLNLQSLNLDIQALACLSALSMIT-ERHGLKEPKRVEELCNKITSSLKDHQSKGQA 575
+ ++ + +D L CL A+ + + GL P VE L K+ +SL+ +
Sbjct: 350 LTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYP 409
Query: 576 LEPTE-SKVLGALVELRKICTLGLQRIFYLKL 606
+P +K+L L LR I L+ +F+ KL
Sbjct: 410 EQPGRFAKLLLRLPALRSIGLKCLEHLFFFKL 441
>gi|18860920 estrogen-related receptor alpha [Homo sapiens]
Length = 423
Score = 164 bits (416), Expect = 2e-40
Identities = 125/402 (31%), Positives = 184/402 (45%), Gaps = 50/402 (12%)
Query: 257 PPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEGT-------------------CAVCGD 297
PP+ L P P + L P + GEG C VCGD
Sbjct: 33 PPVALAPGPAPTRCL--------PGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGD 84
Query: 298 NAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGM 357
A+ HYGV +CE CK FFKRT+Q + +Y C A+ C + KRRR CQ CRF KCL VGM
Sbjct: 85 VASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGM 144
Query: 358 VKEVVRTDSLKGRRGRLPSKPK-------SPLQQEP-SQPSPPSPPICMMNALVRALTDS 409
+KE VR D ++G R + +P+ P P + P +NALV L
Sbjct: 145 LKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVV 204
Query: 410 TPRDLDYSRYCPTDQAAAGTDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLPKEDQTLL 469
P L Y D A V +L I V+ SWA+ IPGF+ L DQ +
Sbjct: 205 EPEKL----YAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSV 260
Query: 470 IESAFLELFVLRLSIRSNTAEDKFVFCNGLVLHRLQC-LRGFGEWLDSIKDFSLNLQSLN 528
++S ++E+ VL ++ RS +D+ F LVL G GE ++ LQ+L
Sbjct: 261 LQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALR 320
Query: 529 LDIQALACLSALSMI-TERHGLKEPKRVEELCNKITSSLKDHQS-----KGQALEPTESK 582
L+ + L AL++ ++ +++ + VE+L + +L ++++ G A +
Sbjct: 321 LEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGR 380
Query: 583 VLGALVELRKICTLGLQRIFYLKLEDLVSPPSIIDKLFLDTL 624
+L L LR+ L + +KLE V + KLFL+ L
Sbjct: 381 LLLTLPLLRQTAGKVLAHFYGVKLEGKVP----MHKLFLEML 418
>gi|238550159 estrogen-related receptor beta [Homo sapiens]
Length = 508
Score = 164 bits (415), Expect = 2e-40
Identities = 136/446 (30%), Positives = 206/446 (46%), Gaps = 48/446 (10%)
Query: 194 KPSPPHPPAPSPAGGHHLGYDPTAAAALSLPLGAAAAAGSQAAALESHPYGL--PLAKRA 251
K P P + A HH P G++ A+G AL +H GL P
Sbjct: 17 KTEPSSPSSGIDALSHHS------------PSGSSDASGGFGLALGTHANGLDSPPMFAG 64
Query: 252 APLAFPPLGLTPSPTASSLLGESP-----SLPSPPSRSSSSGEGTCAVCGDNAACQHYGV 306
A L P + AS ++ +S L + P R C VCGD A+ HYGV
Sbjct: 65 AGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIPKR-------LCLVCGDIASGYHYGV 117
Query: 307 RTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRTDS 366
+CE CK FFKRT+Q N +Y C A C + KRRR CQ CRF KCL VGM+KE VR D
Sbjct: 118 ASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDR 177
Query: 367 LKGRRGRLPSKPKSPLQQEPS-----QPSPPSPPICMMNALVRALTDSTPRDLDYSRYCP 421
++G R K K L E S Q SPP+ + +V L + P L Y
Sbjct: 178 VRGGR----QKYKRRLDSESSPYLSLQISPPAKK--PLTKIVSYLLVAEPDKL----YAM 227
Query: 422 TDQAAAGTDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVLR 481
D + + +L + V WA+ IPGF+ L DQ L++SA++E+ +L
Sbjct: 228 PPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILG 287
Query: 482 LSIRSNTAEDKFVFCNGLVLHRLQC-LRGFGEWLDSIKDFSLNLQSLNLDIQALACLSAL 540
+ RS +DK V+ ++ L G E +I + L ++ + L AL
Sbjct: 288 IVYRSLPYDDKLVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKAL 347
Query: 541 SMI-TERHGLKEPKRVEELCNKITSSLKDHQSKGQALEPTES-KVLGALVELRKICTLGL 598
++ ++ +++ + V++L + + +L+D++ + EP + K+L L LR+ +
Sbjct: 348 ALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAV 407
Query: 599 QRIFYLKLEDLVSPPSIIDKLFLDTL 624
Q + +KL+ V + KLFL+ L
Sbjct: 408 QHFYSVKLQGKVP----MHKLFLEML 429
>gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo
sapiens]
Length = 423
Score = 159 bits (402), Expect = 7e-39
Identities = 129/443 (29%), Positives = 196/443 (44%), Gaps = 57/443 (12%)
Query: 201 PAPSPAGGHHLGYDPTAAAALSLPLGAAAAAGSQAAALESHPYGLPLAKRAAPLAFPPLG 260
P AGG+ G +P A AA G AG Q S AP G
Sbjct: 11 PQDDVAGGNPGGPNPAAQAAR----GGGGGAGEQQQQAGS----------GAPHTPQTPG 56
Query: 261 LTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAACQHYGVRTCEGCKGFFKRTV 320
+P G+ PP S C VCGD ++ +HYG TCEGCK FFKR+V
Sbjct: 57 QPGAPATPGTAGDKGQ--GPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSV 114
Query: 321 QKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRTDSLKGRRGRLPSKPKS 380
++N Y C AN+NCP+D+ RN+CQYCR +KCL VGM +E V +RGR+P +
Sbjct: 115 RRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAV-------QRGRMPPTQPN 167
Query: 381 PLQQEPSQPSPPSPPICMMNALVRALTDSTPRDLDYSRYCPTDQAAAGTDAEHVQQFYNL 440
P Q + P + C ++ + L + P SRY Q + ++ L
Sbjct: 168 PGQYALTNGDPLNGH-CYLSGYISLLLRAEP--YPTSRY--GSQCMQPNNIMGIENICEL 222
Query: 441 LTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCNGLV 500
+ + WA IP F DL DQ L+ + ELFVL N A+ C+ +
Sbjct: 223 AARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVL------NAAQ-----CS-MP 270
Query: 501 LHRLQCLRGFG------------EWLDSIKDFS---LNLQSLNLDIQALACLSALSMIT- 544
LH L G ++D I+ F L++L++D +CL A+ + T
Sbjct: 271 LHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTS 330
Query: 545 ERHGLKEPKRVEELCNKITSSLKDHQSKGQALEPTE-SKVLGALVELRKICTLGLQRIFY 603
+ GL + +E L K +L+++ +P+ K+L L LR + + ++++F+
Sbjct: 331 DACGLSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFF 390
Query: 604 LKLEDLVSPPSIIDKLFLDTLPF 626
++L ++I + L F
Sbjct: 391 VRLVGKTPIETLIRDMLLSGSSF 413
>gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens]
Length = 595
Score = 154 bits (390), Expect = 2e-37
Identities = 120/413 (29%), Positives = 186/413 (45%), Gaps = 50/413 (12%)
Query: 238 LESHPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEGT-----C 292
LE+ P G + + P + P + + G L S + S + E C
Sbjct: 132 LENEPSGYTVREAGPPAFYRP------NSDNRRQGGRERLASTNDKGSMAMESAKETRYC 185
Query: 293 AVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKC 352
AVC D A+ HYGV +CEGCK FFKR++Q + Y+C A C +DK RR CQ CR +KC
Sbjct: 186 AVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKC 245
Query: 353 LSVGMVKEVVRTDSLKGR-----------RGRLPSKPKSPLQQEPSQPSPPSPPICMMNA 401
VGM+K +R D GR GR ++ PSP N+
Sbjct: 246 YEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKNS 305
Query: 402 L---------VRALTDSTPRDLDYSRYCPTDQAAAGTDAEHVQQFYNLLTASIDVSRSWA 452
L V AL D+ P L YS Y PT ++A + NL + +WA
Sbjct: 306 LALSLTADQMVSALLDAEPPIL-YSEYDPT---RPFSEASMMGLLTNLADRELVHMINWA 361
Query: 453 EKIPGFTDLPKEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCNGLVLHRLQ--CLRGF 510
+++PGF DL DQ L+E A+LE+ ++ L RS K +F L+L R Q C+ G
Sbjct: 362 KRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGM 421
Query: 511 GEWLDSIKDFSLNLQSLNLDIQALACLSALSMI---------TERHGLKEPKRVEELCNK 561
E D + S + +NL + CL ++ ++ + L+E + + +K
Sbjct: 422 VEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDK 481
Query: 562 ITSSLKDHQSKG----QALEPTESKVLGALVELRKICTLGLQRIFYLKLEDLV 610
IT +L +K Q +++L L +R + G++ ++ +K +++V
Sbjct: 482 ITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV 534
>gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens]
Length = 595
Score = 154 bits (390), Expect = 2e-37
Identities = 120/413 (29%), Positives = 186/413 (45%), Gaps = 50/413 (12%)
Query: 238 LESHPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEGT-----C 292
LE+ P G + + P + P + + G L S + S + E C
Sbjct: 132 LENEPSGYTVREAGPPAFYRP------NSDNRRQGGRERLASTNDKGSMAMESAKETRYC 185
Query: 293 AVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKC 352
AVC D A+ HYGV +CEGCK FFKR++Q + Y+C A C +DK RR CQ CR +KC
Sbjct: 186 AVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKC 245
Query: 353 LSVGMVKEVVRTDSLKGR-----------RGRLPSKPKSPLQQEPSQPSPPSPPICMMNA 401
VGM+K +R D GR GR ++ PSP N+
Sbjct: 246 YEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKNS 305
Query: 402 L---------VRALTDSTPRDLDYSRYCPTDQAAAGTDAEHVQQFYNLLTASIDVSRSWA 452
L V AL D+ P L YS Y PT ++A + NL + +WA
Sbjct: 306 LALSLTADQMVSALLDAEPPIL-YSEYDPT---RPFSEASMMGLLTNLADRELVHMINWA 361
Query: 453 EKIPGFTDLPKEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCNGLVLHRLQ--CLRGF 510
+++PGF DL DQ L+E A+LE+ ++ L RS K +F L+L R Q C+ G
Sbjct: 362 KRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGM 421
Query: 511 GEWLDSIKDFSLNLQSLNLDIQALACLSALSMI---------TERHGLKEPKRVEELCNK 561
E D + S + +NL + CL ++ ++ + L+E + + +K
Sbjct: 422 VEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDK 481
Query: 562 ITSSLKDHQSKG----QALEPTESKVLGALVELRKICTLGLQRIFYLKLEDLV 610
IT +L +K Q +++L L +R + G++ ++ +K +++V
Sbjct: 482 ITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV 534
>gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens]
Length = 595
Score = 154 bits (390), Expect = 2e-37
Identities = 120/413 (29%), Positives = 186/413 (45%), Gaps = 50/413 (12%)
Query: 238 LESHPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEGT-----C 292
LE+ P G + + P + P + + G L S + S + E C
Sbjct: 132 LENEPSGYTVREAGPPAFYRP------NSDNRRQGGRERLASTNDKGSMAMESAKETRYC 185
Query: 293 AVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKC 352
AVC D A+ HYGV +CEGCK FFKR++Q + Y+C A C +DK RR CQ CR +KC
Sbjct: 186 AVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKC 245
Query: 353 LSVGMVKEVVRTDSLKGR-----------RGRLPSKPKSPLQQEPSQPSPPSPPICMMNA 401
VGM+K +R D GR GR ++ PSP N+
Sbjct: 246 YEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKNS 305
Query: 402 L---------VRALTDSTPRDLDYSRYCPTDQAAAGTDAEHVQQFYNLLTASIDVSRSWA 452
L V AL D+ P L YS Y PT ++A + NL + +WA
Sbjct: 306 LALSLTADQMVSALLDAEPPIL-YSEYDPT---RPFSEASMMGLLTNLADRELVHMINWA 361
Query: 453 EKIPGFTDLPKEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCNGLVLHRLQ--CLRGF 510
+++PGF DL DQ L+E A+LE+ ++ L RS K +F L+L R Q C+ G
Sbjct: 362 KRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGM 421
Query: 511 GEWLDSIKDFSLNLQSLNLDIQALACLSALSMI---------TERHGLKEPKRVEELCNK 561
E D + S + +NL + CL ++ ++ + L+E + + +K
Sbjct: 422 VEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDK 481
Query: 562 ITSSLKDHQSKG----QALEPTESKVLGALVELRKICTLGLQRIFYLKLEDLV 610
IT +L +K Q +++L L +R + G++ ++ +K +++V
Sbjct: 482 ITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV 534
>gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens]
Length = 595
Score = 154 bits (390), Expect = 2e-37
Identities = 120/413 (29%), Positives = 186/413 (45%), Gaps = 50/413 (12%)
Query: 238 LESHPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEGT-----C 292
LE+ P G + + P + P + + G L S + S + E C
Sbjct: 132 LENEPSGYTVREAGPPAFYRP------NSDNRRQGGRERLASTNDKGSMAMESAKETRYC 185
Query: 293 AVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKC 352
AVC D A+ HYGV +CEGCK FFKR++Q + Y+C A C +DK RR CQ CR +KC
Sbjct: 186 AVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKC 245
Query: 353 LSVGMVKEVVRTDSLKGR-----------RGRLPSKPKSPLQQEPSQPSPPSPPICMMNA 401
VGM+K +R D GR GR ++ PSP N+
Sbjct: 246 YEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKNS 305
Query: 402 L---------VRALTDSTPRDLDYSRYCPTDQAAAGTDAEHVQQFYNLLTASIDVSRSWA 452
L V AL D+ P L YS Y PT ++A + NL + +WA
Sbjct: 306 LALSLTADQMVSALLDAEPPIL-YSEYDPT---RPFSEASMMGLLTNLADRELVHMINWA 361
Query: 453 EKIPGFTDLPKEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCNGLVLHRLQ--CLRGF 510
+++PGF DL DQ L+E A+LE+ ++ L RS K +F L+L R Q C+ G
Sbjct: 362 KRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGM 421
Query: 511 GEWLDSIKDFSLNLQSLNLDIQALACLSALSMI---------TERHGLKEPKRVEELCNK 561
E D + S + +NL + CL ++ ++ + L+E + + +K
Sbjct: 422 VEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDK 481
Query: 562 ITSSLKDHQSKG----QALEPTESKVLGALVELRKICTLGLQRIFYLKLEDLV 610
IT +L +K Q +++L L +R + G++ ++ +K +++V
Sbjct: 482 ITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV 534
>gi|14149746 nuclear receptor subfamily 2, group F, member 2 isoform
a [Homo sapiens]
Length = 414
Score = 150 bits (379), Expect = 3e-36
Identities = 122/418 (29%), Positives = 192/418 (45%), Gaps = 73/418 (17%)
Query: 248 AKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEG----------------T 291
A +A P+ PP G +P G + S P+++++ G+G
Sbjct: 23 ASQAPPVPGPPPGAPHTPQTPGQGGPA----STPAQTAAGGQGGPGGPGSDKQQQQQHIE 78
Query: 292 CAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQK 351
C VCGD ++ +HYG TCEGCK FFKR+V++N Y C AN+NCP+D+ RN+CQYCR +K
Sbjct: 79 CVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKK 138
Query: 352 CLSVGMVKEVVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPIC------MMNALVRA 405
CL VGM +E V +RGR+P P P + + + P C ++ L+RA
Sbjct: 139 CLKVGMRREAV-------QRGRMP--PTQPTHGQFALTN-GDPLNCHSYLSGYISLLLRA 188
Query: 406 LTDSTPRDLDYSRYCPTDQAAAGTDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLPKED 465
T R + C G ++ L + + WA IP F DL D
Sbjct: 189 EPYPTSR---FGSQCMQPNNIMG-----IENICELAARMLFSAVEWARNIPFFPDLQITD 240
Query: 466 QTLLIESAFLELFVLRLSIRSNTAEDKFVFCNGLVLHRLQCLRGFG------------EW 513
Q L+ + ELFVL N A+ C+ + LH L G +
Sbjct: 241 QVALLRLTWSELFVL------NAAQ-----CS-MPLHVAPLLAAAGLHASPMSADRVVAF 288
Query: 514 LDSIKDFS---LNLQSLNLDIQALACLSALSMIT-ERHGLKEPKRVEELCNKITSSLKDH 569
+D I+ F L++L++D +CL A+ + T + GL + VE L K +L+++
Sbjct: 289 MDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEY 348
Query: 570 QSKGQALEPTE-SKVLGALVELRKICTLGLQRIFYLKLEDLVSPPSIIDKLFLDTLPF 626
+PT K+L L LR + + ++++F+++L ++I + L F
Sbjct: 349 VRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSF 406
>gi|194294519 nuclear receptor subfamily 1, group H, member 3
isoform c [Homo sapiens]
Length = 402
Score = 147 bits (370), Expect = 4e-35
Identities = 115/381 (30%), Positives = 179/381 (46%), Gaps = 38/381 (9%)
Query: 265 PTASSLLGESPSLPS---PPSRSSSS-----GEGTCAVCGDNAACQHYGVRTCEGCKGFF 316
PTA E PS P+ P R G C+VCGD A+ HY V +CEGCKGFF
Sbjct: 18 PTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFF 77
Query: 317 KRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGM------------VKEVVRT 364
+R+V K A Y+C + +CP+D R +CQ CR +KC GM +K++ R
Sbjct: 78 RRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQ 137
Query: 365 DSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRALTDSTPRDL-DYSRYCPTD 423
+ + LP + SP Q P Q SP + M+ LV A R D R P
Sbjct: 138 EEEQAHATSLPPRASSPPQILP-QLSPEQ--LGMIEKLVAAQQQCNRRSFSDRLRVTPWP 194
Query: 424 QAAAGTDAEHVQQ----FYNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFV 479
A E QQ F L S+ +A+++PGF L +EDQ L++++ +E+ +
Sbjct: 195 MAPDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVML 254
Query: 480 LRLSIRSNTAEDKFVFCNGLVLHRLQCLRG--FGEWLDSIKDFSLNLQSLNLDIQALACL 537
L S R N + F +R + E+++ I +FS + L L+ A L
Sbjct: 255 LETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALL 314
Query: 538 SALSMIT-ERHGLKEPKRVEELCNKITSSL----KDHQSKGQALEPTESKVLGALVELRK 592
A+S+ + +R +++ +VE L + +L H + + P ++L LV LR
Sbjct: 315 IAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFP---RMLMKLVSLRT 371
Query: 593 ICTLGLQRIFYLKLEDLVSPP 613
+ ++ +++F L+L+D PP
Sbjct: 372 LSSVHSEQVFALRLQDKKLPP 392
>gi|194294517 nuclear receptor subfamily 1, group H, member 3
isoform a [Homo sapiens]
Length = 447
Score = 147 bits (370), Expect = 4e-35
Identities = 115/381 (30%), Positives = 179/381 (46%), Gaps = 38/381 (9%)
Query: 265 PTASSLLGESPSLPS---PPSRSSSS-----GEGTCAVCGDNAACQHYGVRTCEGCKGFF 316
PTA E PS P+ P R G C+VCGD A+ HY V +CEGCKGFF
Sbjct: 63 PTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFF 122
Query: 317 KRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGM------------VKEVVRT 364
+R+V K A Y+C + +CP+D R +CQ CR +KC GM +K++ R
Sbjct: 123 RRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQ 182
Query: 365 DSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRALTDSTPRDL-DYSRYCPTD 423
+ + LP + SP Q P Q SP + M+ LV A R D R P
Sbjct: 183 EEEQAHATSLPPRASSPPQILP-QLSPEQ--LGMIEKLVAAQQQCNRRSFSDRLRVTPWP 239
Query: 424 QAAAGTDAEHVQQ----FYNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFV 479
A E QQ F L S+ +A+++PGF L +EDQ L++++ +E+ +
Sbjct: 240 MAPDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVML 299
Query: 480 LRLSIRSNTAEDKFVFCNGLVLHRLQCLRG--FGEWLDSIKDFSLNLQSLNLDIQALACL 537
L S R N + F +R + E+++ I +FS + L L+ A L
Sbjct: 300 LETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALL 359
Query: 538 SALSMIT-ERHGLKEPKRVEELCNKITSSL----KDHQSKGQALEPTESKVLGALVELRK 592
A+S+ + +R +++ +VE L + +L H + + P ++L LV LR
Sbjct: 360 IAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFP---RMLMKLVSLRT 416
Query: 593 ICTLGLQRIFYLKLEDLVSPP 613
+ ++ +++F L+L+D PP
Sbjct: 417 LSSVHSEQVFALRLQDKKLPP 437
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,447,899
Number of Sequences: 37866
Number of extensions: 1698946
Number of successful extensions: 22737
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 348
Number of HSP's successfully gapped in prelim test: 936
Number of HSP's that attempted gapping in prelim test: 13362
Number of HSP's gapped (non-prelim): 6428
length of query: 626
length of database: 18,247,518
effective HSP length: 108
effective length of query: 518
effective length of database: 14,157,990
effective search space: 7333838820
effective search space used: 7333838820
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.