BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Homo sapiens] (598 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Hom... 1227 0.0 gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Hom... 1227 0.0 gi|5453822 nuclear receptor subfamily 4, group A, member 2 [Homo... 610 e-175 gi|27894361 nuclear receptor subfamily 4, group A, member 3 isof... 509 e-144 gi|27894357 nuclear receptor subfamily 4, group A, member 3 isof... 509 e-144 gi|27894355 nuclear receptor subfamily 4, group A, member 3 isof... 509 e-144 gi|27894359 nuclear receptor subfamily 4, group A, member 3 isof... 269 5e-72 gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens] 205 1e-52 gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens] 200 4e-51 gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens] 192 6e-49 gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 191 2e-48 gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 191 2e-48 gi|4506755 retinoid X receptor, alpha [Homo sapiens] 187 2e-47 gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens] 187 3e-47 gi|11415052 retinoid X receptor, beta [Homo sapiens] 182 1e-45 gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens] 181 2e-45 gi|45545429 estrogen-related receptor gamma isoform 2 [Homo sapi... 179 5e-45 gi|45545427 estrogen-related receptor gamma isoform 2 [Homo sapi... 179 5e-45 gi|45545433 estrogen-related receptor gamma isoform 1 [Homo sapi... 179 5e-45 gi|197209821 estrogen-related receptor gamma isoform 2 [Homo sap... 179 5e-45 gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo... 177 2e-44 gi|14149746 nuclear receptor subfamily 2, group F, member 2 isof... 177 3e-44 gi|238550159 estrogen-related receptor beta [Homo sapiens] 175 9e-44 gi|18860920 estrogen-related receptor alpha [Homo sapiens] 175 1e-43 gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Hom... 163 5e-40 gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens] 162 6e-40 gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens] 162 6e-40 gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens] 162 6e-40 gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens] 162 6e-40 gi|194294517 nuclear receptor subfamily 1, group H, member 3 iso... 158 2e-38 >gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Homo sapiens] Length = 598 Score = 1227 bits (3174), Expect = 0.0 Identities = 598/598 (100%), Positives = 598/598 (100%) Query: 1 MPCIQAQYGTPAPSPGPRDHLASDPLTPEFIKPTMDLASPEAAPAAPTALPSFSTFMDGY 60 MPCIQAQYGTPAPSPGPRDHLASDPLTPEFIKPTMDLASPEAAPAAPTALPSFSTFMDGY Sbjct: 1 MPCIQAQYGTPAPSPGPRDHLASDPLTPEFIKPTMDLASPEAAPAAPTALPSFSTFMDGY 60 Query: 61 TGEFDTFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPV 120 TGEFDTFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPV Sbjct: 61 TGEFDTFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPV 120 Query: 121 DEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKA 180 DEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKA Sbjct: 121 DEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKA 180 Query: 181 SGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPHL 240 SGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPHL Sbjct: 181 SGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPHL 240 Query: 241 EGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAK 300 EGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAK Sbjct: 241 EGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAK 300 Query: 301 YICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDAS 360 YICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDAS Sbjct: 301 YICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDAS 360 Query: 361 PANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKW 420 PANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKW Sbjct: 361 PANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKW 420 Query: 421 AEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFG 480 AEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFG Sbjct: 421 AEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFG 480 Query: 481 DWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVA 540 DWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVA Sbjct: 481 DWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVA 540 Query: 541 AVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF 598 AVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF Sbjct: 541 AVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF 598 >gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Homo sapiens] Length = 598 Score = 1227 bits (3174), Expect = 0.0 Identities = 598/598 (100%), Positives = 598/598 (100%) Query: 1 MPCIQAQYGTPAPSPGPRDHLASDPLTPEFIKPTMDLASPEAAPAAPTALPSFSTFMDGY 60 MPCIQAQYGTPAPSPGPRDHLASDPLTPEFIKPTMDLASPEAAPAAPTALPSFSTFMDGY Sbjct: 1 MPCIQAQYGTPAPSPGPRDHLASDPLTPEFIKPTMDLASPEAAPAAPTALPSFSTFMDGY 60 Query: 61 TGEFDTFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPV 120 TGEFDTFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPV Sbjct: 61 TGEFDTFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPV 120 Query: 121 DEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKA 180 DEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKA Sbjct: 121 DEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKA 180 Query: 181 SGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPHL 240 SGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPHL Sbjct: 181 SGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPHL 240 Query: 241 EGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAK 300 EGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAK Sbjct: 241 EGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAK 300 Query: 301 YICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDAS 360 YICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDAS Sbjct: 301 YICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDAS 360 Query: 361 PANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKW 420 PANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKW Sbjct: 361 PANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKW 420 Query: 421 AEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFG 480 AEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFG Sbjct: 421 AEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFG 480 Query: 481 DWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVA 540 DWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVA Sbjct: 481 DWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVA 540 Query: 541 AVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF 598 AVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF Sbjct: 541 AVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF 598 >gi|5453822 nuclear receptor subfamily 4, group A, member 2 [Homo sapiens] Length = 598 Score = 610 bits (1574), Expect = e-175 Identities = 339/634 (53%), Positives = 419/634 (66%), Gaps = 72/634 (11%) Query: 1 MPCIQAQYGTPAPSPGPRDH---------LASDPLTPEFIKPTMDLASPEAAPAAPTALP 51 MPC+QAQYG+ P +SD LTPEF+K +MDL + E A T+LP Sbjct: 1 MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEIT--ATTSLP 58 Query: 52 SFSTFMDGYTGEFDT---FLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQV 108 SFSTFMD Y+ +D LYQ+P S +S K ED Q+ Sbjct: 59 SFSTFMDNYSTGYDVKPPCLYQMP---------------------LSGQQSSIKVEDIQM 97 Query: 109 YGCYP-GPLSGPVDEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWD--GSFGHFSPSQ 165 + L +E + SGS YY P S P+P+TP FQ WD GS +F Sbjct: 98 HNYQQHSHLPPQSEEMMPHSGSVYY-KPSSPPTPTTPGFQVQHSPMWDDPGSLHNF---- 152 Query: 166 TYEGLRAWTEQLPKASGPPQPPAFFSF--SPPTGPSPSLAQS-------PLKLFPSQATH 216 ++ A T + + P + FSF SPP P S P+ P+ +H Sbjct: 153 -HQNYVATTHMIEQRKTPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNPEPA-GSH 210 Query: 217 QLGEGESYSMPT--------AFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGSEGRCA 268 + +G+++++P FPGL S +LDT V S +R G+P +EG CA Sbjct: 211 HVVDGQTFAVPNPIRKPASMGFPGLQIG----HASQLLDTQVPSPPSR-GSPS-NEGLCA 264 Query: 269 VCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQKCL 328 VCGDNA+CQHYGVRTCEGCKGFFKRTVQKNAKY+CLANK+CPVDKRRRNRCQ+CRFQKCL Sbjct: 265 VCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCL 324 Query: 329 AVGMVKEVVRTDSLKGRRGRLPSKPKQP----PDASPANLLTSLVRAHLDSGPSTAKLDY 384 AVGMVKEVVRTDSLKGRRGRLPSKPK P P + P +L+++LVRAH+DS P+ LDY Sbjct: 325 AVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTSLDY 384 Query: 385 SKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFL 444 S+FQ +D +QQFYDLL+GS+E+IR WAEKIPGFA+L ADQDLL ESAFL Sbjct: 385 SRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFL 444 Query: 445 ELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSRSLHSLLVDVPAFA 504 ELF+LRLAYRS P EGKLIFC+G+VLHRLQC RGFG+WIDSI+ FS +L ++ +D+ AF+ Sbjct: 445 ELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFS 504 Query: 505 CLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLGKLPELRT 564 C++AL ++T+RHGL+EP+RVEELQN+I +CLK+HV G + LS+LLGKLPELRT Sbjct: 505 CIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRT 564 Query: 565 LCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF 598 LCTQGLQRIFYLKLEDLVPPP IIDK+F+DTLPF Sbjct: 565 LCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF 598 >gi|27894361 nuclear receptor subfamily 4, group A, member 3 isoform b [Homo sapiens] Length = 637 Score = 509 bits (1310), Expect = e-144 Identities = 312/648 (48%), Positives = 391/648 (60%), Gaps = 72/648 (11%) Query: 1 MPCIQAQYGTPAPSPGPRDHLA--------SDPLTPEFIKPTMDLASPEAAPAAPTALPS 52 MPC+QAQY +PSP + A ++ + P++ K TMDL S E A T+LPS Sbjct: 12 MPCVQAQY---SPSPPGSSYAAQTYSSEYTTEIMNPDYTKLTMDLGSTEITATATTSLPS 68 Query: 53 FSTFMDGYTGEFD---TFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVY 109 STF++GY+ ++ + +YQ+ +P + + + Sbjct: 69 ISTFVEGYSSNYELKPSCVYQMQ---RPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQHQQ 125 Query: 110 GCYPGPLSGPVDEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSF----GHFSPSQ 165 P P S P DE L S+ + SP S +P+TP+F P + WD + G +P Sbjct: 126 PSIP-PASSPEDEVLPSTSMYFKQSPPS--TPTTPAFPPQAGALWDEALPSAPGCIAPGP 182 Query: 166 TYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPS-----------LAQSPLKLFPSQA 214 L + +P +G P F SPP P+PS A + L L P A Sbjct: 183 L---LDPPMKAVPTVAGARFPLFHFKPSPPHPPAPSPAGGHHLGYDPTAAAALSL-PLGA 238 Query: 215 THQLG------EGESYSMPTA-------FPGLAPTSPHLEGSGILDTP-VTSTKARSGAP 260 G E Y +P A FP L T S + ++P + S +RS + Sbjct: 239 AAAAGSQAAALESHPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSS 298 Query: 261 GGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQ 320 G EG CAVCGDNA+CQHYGVRTCEGCKGFFKRTVQKNAKY+CLANK+CPVDKRRRNRCQ Sbjct: 299 G--EGTCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQ 356 Query: 321 FCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQP---------PDASPANLLTSLVRA 371 +CRFQKCL+VGMVKEVVRTDSLKGRRGRLPSKPK P P + P ++ +LVRA Sbjct: 357 YCRFQKCLSVGMVKEVVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRA 416 Query: 372 HLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELS 431 DS P LDYS++ G DA VQQFY+LL+ S++V R WAEKIPGF +L Sbjct: 417 LTDSTP--RDLDYSRYCPTDQAAAG-TDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLP 473 Query: 432 PADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSR 491 DQ LL+ESAFLELF+LRL+ RS E K +FC+GLVLHRLQC RGFG+W+DSI FS Sbjct: 474 KEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCNGLVLHRLQCLRGFGEWLDSIKDFSL 533 Query: 492 SLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVA-AVAGEPQPAS 550 +L SL +D+ A ACLSAL +IT+RHGL+EP+RVEEL N+I S LK+H + A EP Sbjct: 534 NLQSLNLDIQALACLSALSMITERHGLKEPKRVEELCNKITSSLKDHQSKGQALEPTE-- 591 Query: 551 CLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF 598 S++LG L ELR +CT GLQRIFYLKLEDLV PP IIDK+F+DTLPF Sbjct: 592 --SKVLGALVELRKICTLGLQRIFYLKLEDLVSPPSIIDKLFLDTLPF 637 >gi|27894357 nuclear receptor subfamily 4, group A, member 3 isoform a [Homo sapiens] Length = 626 Score = 509 bits (1310), Expect = e-144 Identities = 312/648 (48%), Positives = 391/648 (60%), Gaps = 72/648 (11%) Query: 1 MPCIQAQYGTPAPSPGPRDHLA--------SDPLTPEFIKPTMDLASPEAAPAAPTALPS 52 MPC+QAQY +PSP + A ++ + P++ K TMDL S E A T+LPS Sbjct: 1 MPCVQAQY---SPSPPGSSYAAQTYSSEYTTEIMNPDYTKLTMDLGSTEITATATTSLPS 57 Query: 53 FSTFMDGYTGEFD---TFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVY 109 STF++GY+ ++ + +YQ+ +P + + + Sbjct: 58 ISTFVEGYSSNYELKPSCVYQMQ---RPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQHQQ 114 Query: 110 GCYPGPLSGPVDEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSF----GHFSPSQ 165 P P S P DE L S+ + SP S +P+TP+F P + WD + G +P Sbjct: 115 PSIP-PASSPEDEVLPSTSMYFKQSPPS--TPTTPAFPPQAGALWDEALPSAPGCIAPGP 171 Query: 166 TYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPS-----------LAQSPLKLFPSQA 214 L + +P +G P F SPP P+PS A + L L P A Sbjct: 172 L---LDPPMKAVPTVAGARFPLFHFKPSPPHPPAPSPAGGHHLGYDPTAAAALSL-PLGA 227 Query: 215 THQLG------EGESYSMPTA-------FPGLAPTSPHLEGSGILDTP-VTSTKARSGAP 260 G E Y +P A FP L T S + ++P + S +RS + Sbjct: 228 AAAAGSQAAALESHPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSS 287 Query: 261 GGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQ 320 G EG CAVCGDNA+CQHYGVRTCEGCKGFFKRTVQKNAKY+CLANK+CPVDKRRRNRCQ Sbjct: 288 G--EGTCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQ 345 Query: 321 FCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQP---------PDASPANLLTSLVRA 371 +CRFQKCL+VGMVKEVVRTDSLKGRRGRLPSKPK P P + P ++ +LVRA Sbjct: 346 YCRFQKCLSVGMVKEVVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRA 405 Query: 372 HLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELS 431 DS P LDYS++ G DA VQQFY+LL+ S++V R WAEKIPGF +L Sbjct: 406 LTDSTP--RDLDYSRYCPTDQAAAG-TDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLP 462 Query: 432 PADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSR 491 DQ LL+ESAFLELF+LRL+ RS E K +FC+GLVLHRLQC RGFG+W+DSI FS Sbjct: 463 KEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCNGLVLHRLQCLRGFGEWLDSIKDFSL 522 Query: 492 SLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVA-AVAGEPQPAS 550 +L SL +D+ A ACLSAL +IT+RHGL+EP+RVEEL N+I S LK+H + A EP Sbjct: 523 NLQSLNLDIQALACLSALSMITERHGLKEPKRVEELCNKITSSLKDHQSKGQALEPTE-- 580 Query: 551 CLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF 598 S++LG L ELR +CT GLQRIFYLKLEDLV PP IIDK+F+DTLPF Sbjct: 581 --SKVLGALVELRKICTLGLQRIFYLKLEDLVSPPSIIDKLFLDTLPF 626 >gi|27894355 nuclear receptor subfamily 4, group A, member 3 isoform a [Homo sapiens] Length = 626 Score = 509 bits (1310), Expect = e-144 Identities = 312/648 (48%), Positives = 391/648 (60%), Gaps = 72/648 (11%) Query: 1 MPCIQAQYGTPAPSPGPRDHLA--------SDPLTPEFIKPTMDLASPEAAPAAPTALPS 52 MPC+QAQY +PSP + A ++ + P++ K TMDL S E A T+LPS Sbjct: 1 MPCVQAQY---SPSPPGSSYAAQTYSSEYTTEIMNPDYTKLTMDLGSTEITATATTSLPS 57 Query: 53 FSTFMDGYTGEFD---TFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVY 109 STF++GY+ ++ + +YQ+ +P + + + Sbjct: 58 ISTFVEGYSSNYELKPSCVYQMQ---RPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQHQQ 114 Query: 110 GCYPGPLSGPVDEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSF----GHFSPSQ 165 P P S P DE L S+ + SP S +P+TP+F P + WD + G +P Sbjct: 115 PSIP-PASSPEDEVLPSTSMYFKQSPPS--TPTTPAFPPQAGALWDEALPSAPGCIAPGP 171 Query: 166 TYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPS-----------LAQSPLKLFPSQA 214 L + +P +G P F SPP P+PS A + L L P A Sbjct: 172 L---LDPPMKAVPTVAGARFPLFHFKPSPPHPPAPSPAGGHHLGYDPTAAAALSL-PLGA 227 Query: 215 THQLG------EGESYSMPTA-------FPGLAPTSPHLEGSGILDTP-VTSTKARSGAP 260 G E Y +P A FP L T S + ++P + S +RS + Sbjct: 228 AAAAGSQAAALESHPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSS 287 Query: 261 GGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQ 320 G EG CAVCGDNA+CQHYGVRTCEGCKGFFKRTVQKNAKY+CLANK+CPVDKRRRNRCQ Sbjct: 288 G--EGTCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQ 345 Query: 321 FCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQP---------PDASPANLLTSLVRA 371 +CRFQKCL+VGMVKEVVRTDSLKGRRGRLPSKPK P P + P ++ +LVRA Sbjct: 346 YCRFQKCLSVGMVKEVVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRA 405 Query: 372 HLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELS 431 DS P LDYS++ G DA VQQFY+LL+ S++V R WAEKIPGF +L Sbjct: 406 LTDSTP--RDLDYSRYCPTDQAAAG-TDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLP 462 Query: 432 PADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSR 491 DQ LL+ESAFLELF+LRL+ RS E K +FC+GLVLHRLQC RGFG+W+DSI FS Sbjct: 463 KEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCNGLVLHRLQCLRGFGEWLDSIKDFSL 522 Query: 492 SLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVA-AVAGEPQPAS 550 +L SL +D+ A ACLSAL +IT+RHGL+EP+RVEEL N+I S LK+H + A EP Sbjct: 523 NLQSLNLDIQALACLSALSMITERHGLKEPKRVEELCNKITSSLKDHQSKGQALEPTE-- 580 Query: 551 CLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF 598 S++LG L ELR +CT GLQRIFYLKLEDLV PP IIDK+F+DTLPF Sbjct: 581 --SKVLGALVELRKICTLGLQRIFYLKLEDLVSPPSIIDKLFLDTLPF 626 >gi|27894359 nuclear receptor subfamily 4, group A, member 3 isoform c [Homo sapiens] Length = 443 Score = 269 bits (688), Expect = 5e-72 Identities = 182/440 (41%), Positives = 235/440 (53%), Gaps = 66/440 (15%) Query: 1 MPCIQAQYGTPAPSPGPRDHLA--------SDPLTPEFIKPTMDLASPEAAPAAPTALPS 52 MPC+QAQY +PSP + A ++ + P++ K TMDL S E A T+LPS Sbjct: 1 MPCVQAQY---SPSPPGSSYAAQTYSSEYTTEIMNPDYTKLTMDLGSTEITATATTSLPS 57 Query: 53 FSTFMDGYTGEFD---TFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVY 109 STF++GY+ ++ + +YQ+ +P + + + Sbjct: 58 ISTFVEGYSSNYELKPSCVYQMQ---RPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQHQQ 114 Query: 110 GCYPGPLSGPVDEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSF----GHFSPSQ 165 P P S P DE L S+ + SP S +P+TP+F P + WD + G +P Sbjct: 115 PSIP-PASSPEDEVLPSTSMYFKQSPPS--TPTTPAFPPQAGALWDEALPSAPGCIAPGP 171 Query: 166 TYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPS-----------LAQSPLKLFPSQA 214 L + +P +G P F SPP P+PS A + L L P A Sbjct: 172 L---LDPPMKAVPTVAGARFPLFHFKPSPPHPPAPSPAGGHHLGYDPTAAAALSL-PLGA 227 Query: 215 THQLG------EGESYSMPTA-------FPGLAPTSPHLEGSGILDTP-VTSTKARSGAP 260 G E Y +P A FP L T S + ++P + S +RS + Sbjct: 228 AAAAGSQAAALESHPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSS 287 Query: 261 GGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQ 320 G EG CAVCGDNA+CQHYGVRTCEGCKGFFKRTVQKNAKY+CLANK+CPVDKRRRNRCQ Sbjct: 288 G--EGTCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQ 345 Query: 321 FCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQP---------PDASPANLLTSLVRA 371 +CRFQKCL+VGMVKEVVRTDSLKGRRGRLPSKPK P P + P ++ +LVRA Sbjct: 346 YCRFQKCLSVGMVKEVVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRA 405 Query: 372 HLDSGPSTAKLDYSKFQELV 391 DS P LDYS+ ++ Sbjct: 406 LTDSTP--RDLDYSRVSFMI 423 >gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens] Length = 454 Score = 205 bits (521), Expect = 1e-52 Identities = 146/418 (34%), Positives = 208/418 (49%), Gaps = 37/418 (8%) Query: 202 LAQSPLKLFPSQATHQLGEGESY---SMPTAFPGLAPTSPHLE-------GSGILDTP-- 249 +A + +LF + A LG G Y P AFPG SP E G G D P Sbjct: 1 MATNKERLFAAGA---LGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKE 57 Query: 250 -------VTSTKARSGAPGGSEGR--------CAVCGDNASCQHYGVRTCEGCKGFFKRT 294 ST + P C VC D +S HYGV +CEGCKGFF+R+ Sbjct: 58 MASLSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRS 117 Query: 295 VQKNAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPK 354 +QKN Y C +K+C ++K RNRCQ+CR QKC VGM KE VR D K ++ Sbjct: 118 IQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSP 177 Query: 355 QPPDASP--ANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSG 412 + SP L+T + +AH ++ PS +L H + D G +F +L + Sbjct: 178 DSYELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSA-DHRVQLDLGLWDKFSELATK 236 Query: 413 SLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHR 472 + I ++A+++PGF LS ADQ LL++A L++ +LR+ R P + + F GL L+R Sbjct: 237 CIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNR 296 Query: 473 LQCAR-GFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLIT-DRHGLQEPRRVEELQNR 530 Q GFG D + AF+ L L +D LSA+ LI DR L+EP +V++LQ Sbjct: 297 TQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEP 356 Query: 531 IASCLKEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPII 588 + L+ + A P R+L K+ +LR + T+G +R LK+E P PP+I Sbjct: 357 LLEALR--LYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLI 412 >gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens] Length = 443 Score = 200 bits (508), Expect = 4e-51 Identities = 123/326 (37%), Positives = 180/326 (55%), Gaps = 7/326 (2%) Query: 267 CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQK 326 C VC D +S HYGV +CEGCKGFF+R++QKN Y C +K+C ++K RNRCQ+CR QK Sbjct: 79 CFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 138 Query: 327 CLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDASP--ANLLTSLVRAHLDSGPSTAKLDY 384 C VGM KE VR D K ++ + SP L+T + +AH ++ PS +L Sbjct: 139 CFEVGMSKEAVRNDRNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQETFPSLCQLGK 198 Query: 385 SKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFL 444 H + D G +F +L + + I ++A+++PGF LS ADQ LL++A L Sbjct: 199 YTTNSSA-DHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACL 257 Query: 445 ELFILRLAYRSKPGEGKLIFCSGLVLHRLQCAR-GFGDWIDSILAFSRSLHSLLVDVPAF 503 ++ +LR+ R P + + F GL L+R Q GFG D + AF+ L L +D Sbjct: 258 DILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTET 317 Query: 504 ACLSALVLIT-DRHGLQEPRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLGKLPEL 562 LSA+ LI DR L+EP +V++LQ + L+ + A P R+L K+ +L Sbjct: 318 GLLSAICLICGDRMDLEEPEKVDKLQEPLLEALR--LYARRRRPSQPYMFPRMLMKITDL 375 Query: 563 RTLCTQGLQRIFYLKLEDLVPPPPII 588 R + T+G +R LK+E P PP+I Sbjct: 376 RGISTKGAERAITLKMEIPGPMPPLI 401 >gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens] Length = 448 Score = 192 bits (489), Expect = 6e-49 Identities = 126/378 (33%), Positives = 195/378 (51%), Gaps = 14/378 (3%) Query: 225 SMPTAFPGLAPTS-PHLEGSGILDTPVTSTKARSGAPGGS------EGRCAVCGDNASCQ 277 ++ F GL T H + ++T TS++ +P C VC D +S Sbjct: 32 ALKACFSGLTQTEWQHRHTAQSIETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGY 91 Query: 278 HYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVV 337 HYGV CEGCKGFF+R++QKN Y C +K+C ++K RNRCQ+CR QKC VGM KE V Sbjct: 92 HYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESV 151 Query: 338 RTDSLKGRR--GRLPSKPKQPPDASPANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHF 395 R D K ++ + A +L + +AH ++ PS +L H Sbjct: 152 RNDRNKKKKETSKQECTESYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSA-DHR 210 Query: 396 GKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRS 455 + D G +F +L + + I ++A+++PGF L+ ADQ LL++A L++ ILR+ R Sbjct: 211 VRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRY 270 Query: 456 KPGEGKLIFCSGLVLHRLQCAR-GFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLIT- 513 P + + F GL L+R Q GFG D + F+ L L +D LSA+ LI Sbjct: 271 TPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICG 330 Query: 514 DRHGLQEPRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRI 573 DR L+EP +V++LQ + LK ++ P ++L K+ +LR++ +G +R+ Sbjct: 331 DRQDLEEPTKVDKLQEPLLEALKIYIR--KRRPSKPHMFPKILMKITDLRSISAKGAERV 388 Query: 574 FYLKLEDLVPPPPIIDKI 591 LK+E PP+I ++ Sbjct: 389 ITLKMEIPGSMPPLIQEM 406 >gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens] Length = 462 Score = 191 bits (485), Expect = 2e-48 Identities = 144/431 (33%), Positives = 213/431 (49%), Gaps = 39/431 (9%) Query: 181 SGPPQPPAFFSFSPPTGP-SPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPH 239 +G P PP F F P G SP A + L+ HQL YS P+ P T Sbjct: 17 NGYPVPPYAFFFPPMLGGLSPPGALTTLQ-------HQLPVS-GYSTPS--PATIETQSS 66 Query: 240 LEGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNA 299 + P R P C VC D +S HYGV CEGCKGFF+R++QKN Sbjct: 67 SSEEIVPSPPSPPPLPRIYKP------CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM 120 Query: 300 KYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDA 359 Y C +K+C ++K RNRCQ+CR QKC VGM KE VR D K ++ + + Sbjct: 121 VYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTL 180 Query: 360 SP--ANLLTSLVRAHLDSGPSTAKL-----DYSKFQELVLPHFGKEDAGDVQQFYDLLSG 412 +P L+ + +AH ++ P+ +L + S Q + L D +F +L + Sbjct: 181 TPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSL------DIDLWDKFSELSTK 234 Query: 413 SLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHR 472 + ++A+++PGF L+ ADQ LL++A L++ ILR+ R P + + F GL L+R Sbjct: 235 CIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNR 294 Query: 473 LQCAR-GFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLIT-DRHGLQEPRRVEELQNR 530 Q GFG D + AF+ L L +D LSA+ LI DR L++P RV+ LQ Sbjct: 295 TQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEP 354 Query: 531 IASCLKEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDK 590 + LK +V P ++L K+ +LR++ +G +R+ LK+E PP+I + Sbjct: 355 LLEALKVYVR--KRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQE 412 Query: 591 IF-----MDTL 596 + +DTL Sbjct: 413 MLENSEGLDTL 423 >gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens] Length = 462 Score = 191 bits (485), Expect = 2e-48 Identities = 144/431 (33%), Positives = 213/431 (49%), Gaps = 39/431 (9%) Query: 181 SGPPQPPAFFSFSPPTGP-SPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPH 239 +G P PP F F P G SP A + L+ HQL YS P+ P T Sbjct: 17 NGYPVPPYAFFFPPMLGGLSPPGALTTLQ-------HQLPVS-GYSTPS--PATIETQSS 66 Query: 240 LEGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNA 299 + P R P C VC D +S HYGV CEGCKGFF+R++QKN Sbjct: 67 SSEEIVPSPPSPPPLPRIYKP------CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM 120 Query: 300 KYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDA 359 Y C +K+C ++K RNRCQ+CR QKC VGM KE VR D K ++ + + Sbjct: 121 VYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTL 180 Query: 360 SP--ANLLTSLVRAHLDSGPSTAKL-----DYSKFQELVLPHFGKEDAGDVQQFYDLLSG 412 +P L+ + +AH ++ P+ +L + S Q + L D +F +L + Sbjct: 181 TPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSL------DIDLWDKFSELSTK 234 Query: 413 SLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHR 472 + ++A+++PGF L+ ADQ LL++A L++ ILR+ R P + + F GL L+R Sbjct: 235 CIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNR 294 Query: 473 LQCAR-GFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLIT-DRHGLQEPRRVEELQNR 530 Q GFG D + AF+ L L +D LSA+ LI DR L++P RV+ LQ Sbjct: 295 TQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEP 354 Query: 531 IASCLKEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDK 590 + LK +V P ++L K+ +LR++ +G +R+ LK+E PP+I + Sbjct: 355 LLEALKVYVR--KRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQE 412 Query: 591 IF-----MDTL 596 + +DTL Sbjct: 413 MLENSEGLDTL 423 >gi|4506755 retinoid X receptor, alpha [Homo sapiens] Length = 462 Score = 187 bits (476), Expect = 2e-47 Identities = 145/467 (31%), Positives = 225/467 (48%), Gaps = 36/467 (7%) Query: 134 SPCSAPSPSTPSFQPPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKASGPPQPPAFFSFS 193 SP S + PS P L P GS P Q + + + + GPP F S Sbjct: 21 SPTGRGSMAAPSLHP-SLGPGIGS-----PGQLHSPISTLSSPI-NGMGPP----FSVIS 69 Query: 194 PPTGP-SPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPHLEGSGILDTPVTS 252 P GP S S+ +P F + G + S P L +G+L P Sbjct: 70 SPMGPHSMSVPTTPTLGFST------GSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHP 123 Query: 253 TKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVD 312 + ++ CA+CGD +S +HYGV +CEGCKGFFKRTV+K+ Y C NKDC +D Sbjct: 124 S---GNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLID 180 Query: 313 KRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDASPANLLTSLVRAH 372 KR+RNRCQ+CR+QKCLA+GM +E V+ + +G + R ++ + A+ + ++ A Sbjct: 181 KRQRNRCQYCRYQKCLAMGMKREAVQEERQRG-KDRNENEVESTSSANEDMPVERILEAE 239 Query: 373 LDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSP 432 L P T Y + + P + ++ Q D L + +WA++IP F+EL Sbjct: 240 LAVEPKTE--TYVEANMGLNPSSPNDPVTNICQAAD---KQLFTLVEWAKRIPHFSELPL 294 Query: 433 ADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQC-ARGFGDWIDSILA-FS 490 DQ +LL + + EL I ++RS + ++ +GL +HR + G G D +L Sbjct: 295 DDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELV 354 Query: 491 RSLHSLLVDVPAFACLSALVLIT-DRHGLQEPRRVEELQNRIASCLKEHVAAVAGEPQPA 549 + + +D CL A+VL D GL P VE L+ ++ + L+ + P+ Sbjct: 355 SKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAY--CKHKYPEQP 412 Query: 550 SCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTL 596 ++LL +LP LR++ + L+ +F+ KL P ID M+ L Sbjct: 413 GRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTP----IDTFLMEML 455 >gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens] Length = 457 Score = 187 bits (474), Expect = 3e-47 Identities = 121/344 (35%), Positives = 185/344 (53%), Gaps = 22/344 (6%) Query: 267 CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQK 326 C VC D +S HYGV CEGCKGFF+R++QKN Y C +K+C ++K RNRCQ+CR QK Sbjct: 83 CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 142 Query: 327 CLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDASP--ANLLTSLVRAHLDSGPSTAKL-- 382 C VGM KE VR D K ++ + + +P L+ + +AH ++ P+ +L Sbjct: 143 CFEVGMSKESVRNDRNKKKKEVPKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLGK 202 Query: 383 ---DYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLL 439 + S Q + L D +F +L + + ++A+++PGF L+ ADQ LL Sbjct: 203 YTTNNSSEQRVSL------DIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLL 256 Query: 440 ESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCAR-GFGDWIDSILAFSRSLHSLLV 498 ++A L++ ILR+ R P + + F GL L+R Q GFG D + AF+ L L + Sbjct: 257 KAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEM 316 Query: 499 DVPAFACLSALVLIT-DRHGLQEPRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLG 557 D LSA+ LI DR L++P RV+ LQ + LK +V P ++L Sbjct: 317 DDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVR--KRRPSRPHMFPKMLM 374 Query: 558 KLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIF-----MDTL 596 K+ +LR++ +G +R+ LK+E PP+I ++ +DTL Sbjct: 375 KITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGLDTL 418 >gi|11415052 retinoid X receptor, beta [Homo sapiens] Length = 533 Score = 182 bits (461), Expect = 1e-45 Identities = 141/453 (31%), Positives = 205/453 (45%), Gaps = 50/453 (11%) Query: 177 LPKASGPPQPPAFFSFSPPTGPS--PSLAQSPLKLFPSQATHQLGEG-ESYSMPTAFPGL 233 LP+ PP PP PP PS PSL S P LG S PGL Sbjct: 91 LPQGVPPPSPPG-----PPLPPSTAPSLGGSGAPPPPPMPPPPLGSPFPVISSSMGSPGL 145 Query: 234 APTSP----------------HLEGSGI-----LDTPVTSTKARS-----GAPGGSEGRC 267 P +P L G G + PV + G PG + C Sbjct: 146 PPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPPPPGGPGAGKRLC 205 Query: 268 AVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQKC 327 A+CGD +S +HYGV +CEGCKGFFKRT++K+ Y C NKDC VDKR+RNRCQ+CR+QKC Sbjct: 206 AICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKC 265 Query: 328 LAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDASPANL-LTSLVRAHLDSGPSTAKLDYSK 386 LA GM +E V+ + +RG+ + +P + + ++ A L K D Sbjct: 266 LATGMKREAVQEER---QRGKDKDGDGEGAGGAPEEMPVDRILEAEL---AVEQKSDQGV 319 Query: 387 FQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLEL 446 G V L + +WA++IP F+ L DQ +LL + + EL Sbjct: 320 EGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNEL 379 Query: 447 FILRLAYRSKPGEGKLIFCSGLVLHRLQC-ARGFGDWIDSILA-FSRSLHSLLVDVPAFA 504 I ++RS ++ +GL +HR + G G D +L + + +D Sbjct: 380 LIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMRMDKTELG 439 Query: 505 CLSALVLIT-DRHGLQEPRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLGKLPELR 563 CL A++L D GL P VE L+ ++ + L+ + P+ ++LL +LP LR Sbjct: 440 CLRAIILFNPDAKGLSNPSEVEVLREKVYASLETY--CKQKYPEQQGRFAKLLLRLPALR 497 Query: 564 TLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTL 596 ++ + L+ +F+ KL P ID M+ L Sbjct: 498 SIGLKCLEHLFFFKLIGDTP----IDTFLMEML 526 >gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens] Length = 463 Score = 181 bits (458), Expect = 2e-45 Identities = 131/421 (31%), Positives = 207/421 (49%), Gaps = 33/421 (7%) Query: 180 ASGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPH 239 A G P + PP+G +LA P + + QL S S L P Sbjct: 65 ALGSPYRVITSAMGPPSG---ALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPL----PG 117 Query: 240 LEGSGILDTPVTSTKARSGAPGGSEGR-CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKN 298 L G G ++ P TS PG CA+CGD +S +HYGV +CEGCKGFFKRT++K+ Sbjct: 118 LPGIGNMNYPSTS-------PGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKD 170 Query: 299 AKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPD 358 Y C NKDC +DKR+RNRCQ+CR+QKCL +GM +E V+ + + R R S+ + Sbjct: 171 LIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRE-RAESEAECATS 229 Query: 359 ASPANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIR 418 + ++ A L P T + ++ + + + ++ D L + Sbjct: 230 GHEDMPVERILEAELAVEPKT-----ESYGDMNMENSTNDPVTNICHAAD---KQLFTLV 281 Query: 419 KWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQC-AR 477 +WA++IP F++L+ DQ +LL + + EL I ++RS + ++ +GL +HR + Sbjct: 282 EWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSA 341 Query: 478 GFGDWIDSILA-FSRSLHSLLVDVPAFACLSALVLIT-DRHGLQEPRRVEELQNRIASCL 535 G G D +L + + +D CL A+VL D GL P VE L+ ++ + L Sbjct: 342 GVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATL 401 Query: 536 KEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDT 595 + + P+ ++LL +LP LR++ + L+ +F+ KL P ID M+ Sbjct: 402 EAYTK--QKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTP----IDTFLMEM 455 Query: 596 L 596 L Sbjct: 456 L 456 >gi|45545429 estrogen-related receptor gamma isoform 2 [Homo sapiens] Length = 435 Score = 179 bits (455), Expect = 5e-45 Identities = 131/388 (33%), Positives = 192/388 (49%), Gaps = 37/388 (9%) Query: 231 PGLAPTSPHLEGSG------------ILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQH 278 P L P++P L GSG I++ P TK + C VCGD AS H Sbjct: 59 PPLYPSAPILGGSGPVRKLYDDCSSTIVEDP--QTKCEYMLNSMPKRLCLVCGDIASGYH 116 Query: 279 YGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVR 338 YGV +CE CK FFKRT+Q N +Y C A +C + KRRR CQ CRF KCL VGM+KE VR Sbjct: 117 YGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVR 176 Query: 339 TDSLKGRRGRLP-------SKPKQPPDASPANLLTSLVRAHLDSGPSTAKLDYSKFQELV 391 D ++G R + S P PA + + +HL + K + Sbjct: 177 LDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHL------LVAEPEKIYAMP 230 Query: 392 LPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRL 451 P D + DL L VI WA+ IPGF+ LS ADQ LL+SA++E+ IL + Sbjct: 231 DPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGV 290 Query: 452 AYRSKPGEGKLIFCSGLVLHRLQC-ARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALV 510 YRS E +L++ ++ Q G D ++IL + S+ ++ F L A+ Sbjct: 291 VYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIA 350 Query: 511 LI-TDRHGLQEPRRVEELQNRIASCLKEHVAAVAGE-PQPASCLSRLLGKLPELRTLCTQ 568 L +D +++ V++LQ+ + L+++ A E P+ A ++L LP LR T+ Sbjct: 351 LANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRA---GKMLMTLPLLRQTSTK 407 Query: 569 GLQRIFYLKLEDLVPPPPIIDKIFMDTL 596 +Q + +KLE VP + K+F++ L Sbjct: 408 AVQHFYNIKLEGKVP----MHKLFLEML 431 >gi|45545427 estrogen-related receptor gamma isoform 2 [Homo sapiens] Length = 435 Score = 179 bits (455), Expect = 5e-45 Identities = 131/388 (33%), Positives = 192/388 (49%), Gaps = 37/388 (9%) Query: 231 PGLAPTSPHLEGSG------------ILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQH 278 P L P++P L GSG I++ P TK + C VCGD AS H Sbjct: 59 PPLYPSAPILGGSGPVRKLYDDCSSTIVEDP--QTKCEYMLNSMPKRLCLVCGDIASGYH 116 Query: 279 YGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVR 338 YGV +CE CK FFKRT+Q N +Y C A +C + KRRR CQ CRF KCL VGM+KE VR Sbjct: 117 YGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVR 176 Query: 339 TDSLKGRRGRLP-------SKPKQPPDASPANLLTSLVRAHLDSGPSTAKLDYSKFQELV 391 D ++G R + S P PA + + +HL + K + Sbjct: 177 LDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHL------LVAEPEKIYAMP 230 Query: 392 LPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRL 451 P D + DL L VI WA+ IPGF+ LS ADQ LL+SA++E+ IL + Sbjct: 231 DPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGV 290 Query: 452 AYRSKPGEGKLIFCSGLVLHRLQC-ARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALV 510 YRS E +L++ ++ Q G D ++IL + S+ ++ F L A+ Sbjct: 291 VYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIA 350 Query: 511 LI-TDRHGLQEPRRVEELQNRIASCLKEHVAAVAGE-PQPASCLSRLLGKLPELRTLCTQ 568 L +D +++ V++LQ+ + L+++ A E P+ A ++L LP LR T+ Sbjct: 351 LANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRA---GKMLMTLPLLRQTSTK 407 Query: 569 GLQRIFYLKLEDLVPPPPIIDKIFMDTL 596 +Q + +KLE VP + K+F++ L Sbjct: 408 AVQHFYNIKLEGKVP----MHKLFLEML 431 >gi|45545433 estrogen-related receptor gamma isoform 1 [Homo sapiens] Length = 458 Score = 179 bits (455), Expect = 5e-45 Identities = 131/388 (33%), Positives = 192/388 (49%), Gaps = 37/388 (9%) Query: 231 PGLAPTSPHLEGSG------------ILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQH 278 P L P++P L GSG I++ P TK + C VCGD AS H Sbjct: 82 PPLYPSAPILGGSGPVRKLYDDCSSTIVEDP--QTKCEYMLNSMPKRLCLVCGDIASGYH 139 Query: 279 YGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVR 338 YGV +CE CK FFKRT+Q N +Y C A +C + KRRR CQ CRF KCL VGM+KE VR Sbjct: 140 YGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVR 199 Query: 339 TDSLKGRRGRLP-------SKPKQPPDASPANLLTSLVRAHLDSGPSTAKLDYSKFQELV 391 D ++G R + S P PA + + +HL + K + Sbjct: 200 LDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHL------LVAEPEKIYAMP 253 Query: 392 LPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRL 451 P D + DL L VI WA+ IPGF+ LS ADQ LL+SA++E+ IL + Sbjct: 254 DPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGV 313 Query: 452 AYRSKPGEGKLIFCSGLVLHRLQC-ARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALV 510 YRS E +L++ ++ Q G D ++IL + S+ ++ F L A+ Sbjct: 314 VYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIA 373 Query: 511 LI-TDRHGLQEPRRVEELQNRIASCLKEHVAAVAGE-PQPASCLSRLLGKLPELRTLCTQ 568 L +D +++ V++LQ+ + L+++ A E P+ A ++L LP LR T+ Sbjct: 374 LANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRA---GKMLMTLPLLRQTSTK 430 Query: 569 GLQRIFYLKLEDLVPPPPIIDKIFMDTL 596 +Q + +KLE VP + K+F++ L Sbjct: 431 AVQHFYNIKLEGKVP----MHKLFLEML 454 >gi|197209821 estrogen-related receptor gamma isoform 2 [Homo sapiens] Length = 435 Score = 179 bits (455), Expect = 5e-45 Identities = 131/388 (33%), Positives = 192/388 (49%), Gaps = 37/388 (9%) Query: 231 PGLAPTSPHLEGSG------------ILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQH 278 P L P++P L GSG I++ P TK + C VCGD AS H Sbjct: 59 PPLYPSAPILGGSGPVRKLYDDCSSTIVEDP--QTKCEYMLNSMPKRLCLVCGDIASGYH 116 Query: 279 YGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVR 338 YGV +CE CK FFKRT+Q N +Y C A +C + KRRR CQ CRF KCL VGM+KE VR Sbjct: 117 YGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVR 176 Query: 339 TDSLKGRRGRLP-------SKPKQPPDASPANLLTSLVRAHLDSGPSTAKLDYSKFQELV 391 D ++G R + S P PA + + +HL + K + Sbjct: 177 LDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHL------LVAEPEKIYAMP 230 Query: 392 LPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRL 451 P D + DL L VI WA+ IPGF+ LS ADQ LL+SA++E+ IL + Sbjct: 231 DPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGV 290 Query: 452 AYRSKPGEGKLIFCSGLVLHRLQC-ARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALV 510 YRS E +L++ ++ Q G D ++IL + S+ ++ F L A+ Sbjct: 291 VYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIA 350 Query: 511 LI-TDRHGLQEPRRVEELQNRIASCLKEHVAAVAGE-PQPASCLSRLLGKLPELRTLCTQ 568 L +D +++ V++LQ+ + L+++ A E P+ A ++L LP LR T+ Sbjct: 351 LANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRA---GKMLMTLPLLRQTSTK 407 Query: 569 GLQRIFYLKLEDLVPPPPIIDKIFMDTL 596 +Q + +KLE VP + K+F++ L Sbjct: 408 AVQHFYNIKLEGKVP----MHKLFLEML 431 >gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo sapiens] Length = 423 Score = 177 bits (449), Expect = 2e-44 Identities = 133/421 (31%), Positives = 197/421 (46%), Gaps = 44/421 (10%) Query: 195 PTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPHLEGS-GILDTPVTST 253 P GP+P+ +QA G G A G AP +P G G TP T+ Sbjct: 20 PGGPNPA----------AQAARGGGGGAGEQQQQAGSG-APHTPQTPGQPGAPATPGTAG 68 Query: 254 KARSGAPGGSEGR----CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDC 309 G PG + + C VCGD +S +HYG TCEGCK FFKR+V++N Y C AN++C Sbjct: 69 DKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNC 128 Query: 310 PVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQP-----PDASPAN- 363 P+D+ RN+CQ+CR +KCL VGM +E V+ RGR+P P + P N Sbjct: 129 PIDQHHRNQCQYCRLKKCLKVGMRREAVQ-------RGRMPPTQPNPGQYALTNGDPLNG 181 Query: 364 --LLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWA 421 L+ + L + P S+ + + ++ +L + L +WA Sbjct: 182 HCYLSGYISLLLRAEPYPTSRYGSQCMQ-------PNNIMGIENICELAARLLFSAVEWA 234 Query: 422 EKIPGFAELSPADQDLLLESAFLELFILRLAYRSKP-GEGKLIFCSGLVLHRLQCAR--G 478 IP F +L DQ LL + ELF+L A S P L+ +GL + R Sbjct: 235 RNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVA 294 Query: 479 FGDWIDSILAFSRSLHSLLVDVPAFACLSALVLIT-DRHGLQEPRRVEELQNRIASCLKE 537 F D I L +L VD ++CL A+VL T D GL + +E LQ + L+E Sbjct: 295 FMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEE 354 Query: 538 HVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLP 597 +V + P S +LL +LP LRT+ + ++++F+++L P +I + + Sbjct: 355 YVR--SQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSS 412 Query: 598 F 598 F Sbjct: 413 F 413 >gi|14149746 nuclear receptor subfamily 2, group F, member 2 isoform a [Homo sapiens] Length = 414 Score = 177 bits (448), Expect = 3e-44 Identities = 127/401 (31%), Positives = 187/401 (46%), Gaps = 35/401 (8%) Query: 220 EGESYSMPTAFPGLAPTSPHLEGS----GILDTPVTSTKARSGAPGGSEG---------R 266 +G S PG P +PH + G TP + G PGG Sbjct: 19 QGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIE 78 Query: 267 CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQK 326 C VCGD +S +HYG TCEGCK FFKR+V++N Y C AN++CP+D+ RN+CQ+CR +K Sbjct: 79 CVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKK 138 Query: 327 CLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDASPANLLTSLVRAHLDSGPSTAKLDYSK 386 CL VGM +E V+ RGR+P P QP A + H + L + Sbjct: 139 CLKVGMRREAVQ-------RGRMP--PTQPTHGQFALTNGDPLNCHSYLSGYISLL--LR 187 Query: 387 FQELVLPHFGKE-----DAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLES 441 + FG + + ++ +L + L +WA IP F +L DQ LL Sbjct: 188 AEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRL 247 Query: 442 AFLELFILRLAYRSKP-GEGKLIFCSGLVLHRLQCAR--GFGDWIDSILAFSRSLHSLLV 498 + ELF+L A S P L+ +GL + R F D I L +L V Sbjct: 248 TWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHV 307 Query: 499 DVPAFACLSALVLIT-DRHGLQEPRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLG 557 D ++CL A+VL T D GL + VE LQ + L+E+V + P + +LL Sbjct: 308 DSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVR--SQYPNQPTRFGKLLL 365 Query: 558 KLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF 598 +LP LRT+ + ++++F+++L P +I + + F Sbjct: 366 RLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSF 406 >gi|238550159 estrogen-related receptor beta [Homo sapiens] Length = 508 Score = 175 bits (444), Expect = 9e-44 Identities = 119/338 (35%), Positives = 173/338 (51%), Gaps = 19/338 (5%) Query: 267 CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQK 326 C VCGD AS HYGV +CE CK FFKRT+Q N +Y C A +C + KRRR CQ CRF K Sbjct: 103 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 162 Query: 327 CLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDASPANLLTSLVRAHLDSGPSTAKLDY-- 384 CL VGM+KE VR D ++G GR K + ++SP SL + P T + Y Sbjct: 163 CLKVGMLKEGVRLDRVRG--GRQKYKRRLDSESSP---YLSLQISPPAKKPLTKIVSYLL 217 Query: 385 ----SKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLE 440 K + P + D + DL L VI WA+ IPGF+ LS DQ LL+ Sbjct: 218 VAEPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQ 277 Query: 441 SAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQC-ARGFGDWIDSILAFSRSLHSLLVD 499 SA++E+ IL + YRS P + KL++ ++ G + +IL R L V+ Sbjct: 278 SAWMEILILGIVYRSLPYDDKLVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVE 337 Query: 500 VPAFACLSALVLI-TDRHGLQEPRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLGK 558 F L AL L +D +++ V++LQ+ + L+++ + E + +LL Sbjct: 338 KEEFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEPWRT--GKLLLT 395 Query: 559 LPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTL 596 LP LR + +Q + +KL+ VP + K+F++ L Sbjct: 396 LPLLRQTAAKAVQHFYSVKLQGKVP----MHKLFLEML 429 >gi|18860920 estrogen-related receptor alpha [Homo sapiens] Length = 423 Score = 175 bits (443), Expect = 1e-43 Identities = 138/433 (31%), Positives = 199/433 (45%), Gaps = 45/433 (10%) Query: 178 PKASGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTS 237 P + P+ + PP +P A P + P + GEG Sbjct: 17 PASPDSPKGSSETETEPPVALAPGPA--PTRCLPGHKEEEDGEG--------------AG 60 Query: 238 PHLEGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQK 297 P +G G L S P + C VCGD AS HYGV +CE CK FFKRT+Q Sbjct: 61 PGEQGGGKL--------VLSSLP---KRLCLVCGDVASGYHYGVASCEACKAFFKRTIQG 109 Query: 298 NAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQP- 356 + +Y C A+ +C + KRRR CQ CRF KCL VGM+KE VR D ++G R + +P+ Sbjct: 110 SIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDP 169 Query: 357 ---PDASPANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGD------VQQFY 407 P PA L + P A + + E + + AG V Sbjct: 170 LPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLC 229 Query: 408 DLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSG 467 DL + V WA+ IPGF+ LS +DQ +L+S ++E+ +L +A RS P + +L F Sbjct: 230 DLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAED 289 Query: 468 LVLHRLQC-ARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLI-TDRHGLQEPRRVE 525 LVL A G G+ ++L R L +L ++ + L AL L +D +++ VE Sbjct: 290 LVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVE 349 Query: 526 ELQNRIASCLKEHVAAVAGEPQPAS--CLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVP 583 +L+ + L E+ A AG A RLL LP LR + L + +KLE VP Sbjct: 350 QLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVP 409 Query: 584 PPPIIDKIFMDTL 596 + K+F++ L Sbjct: 410 ----MHKLFLEML 418 >gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Homo sapiens] Length = 404 Score = 163 bits (412), Expect = 5e-40 Identities = 123/377 (32%), Positives = 175/377 (46%), Gaps = 35/377 (9%) Query: 247 DTPVTSTKARSGAPGGSEGR------CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAK 300 D + A S A G E R C VCGD +S +HYGV TCEGCK FFKR++++N Sbjct: 30 DDSASPPGAASDAEPGDEERPGLQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLS 89 Query: 301 YICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDAS 360 Y C +N+DC +D+ RN+CQ+CR +KC VGM KE V+ RGR+P AS Sbjct: 90 YTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQ-------RGRIPHSLPGAVAAS 142 Query: 361 PANLLTSLVRAHLDSGPSTAKLDYSKFQELVL---PH---FGKEDAGD--------VQQF 406 + S + A G S+ +L P+ G+ AG + Sbjct: 143 SGSPPGSALAAVASGGDLFPGQPVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNV 202 Query: 407 YDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKP-GEGKLIFC 465 +L + L +WA P F EL ADQ LL ++ ELF+L A + P L+ Sbjct: 203 CELAARLLFSTVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLAA 262 Query: 466 SGLVLHRLQCARGFGDWIDSILAFSR---SLHSLLVDVPAFACLSALVLIT-DRHGLQEP 521 +GL + R ++D + AF L L VD + CL A+ L T D GL +P Sbjct: 263 AGLHAAPMAAERAVA-FMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDP 321 Query: 522 RRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDL 581 VE LQ + L E+V A P RLL +LP LR + + ++F+++L Sbjct: 322 AHVESLQEKAQVALTEYVR--AQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGK 379 Query: 582 VPPPPIIDKIFMDTLPF 598 P +I + + F Sbjct: 380 TPIETLIRDMLLSGSTF 396 >gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens] Length = 595 Score = 162 bits (411), Expect = 6e-40 Identities = 151/539 (28%), Positives = 230/539 (42%), Gaps = 109/539 (20%) Query: 96 PASASFKFE-----DFQVYGCYPGPLSGPVDEALSSSGSDYYGSP---CSAPSPSTPSFQ 147 P A+++F + QVYG G GP EA + + G P +PSP Sbjct: 55 PEGAAYEFNAAAAANAQVYG-QTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHP 113 Query: 148 PPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPSLAQSPL 207 PPQLSP+ L+ +Q+P ++ + P+G + A P Sbjct: 114 PPQLSPF---------------LQPHGQQVP----------YYLENEPSGYTVREAGPPA 148 Query: 208 KLFPSQATHQLGEGESYSMPTAFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGSEGR- 266 P+ + G E + T+ K E R Sbjct: 149 FYRPNSDNRRQGGRERLAS------------------------TNDKGSMAMESAKETRY 184 Query: 267 CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQK 326 CAVC D AS HYGV +CEGCK FFKR++Q + Y+C A C +DK RR CQ CR +K Sbjct: 185 CAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRK 244 Query: 327 CLAVGMVKEVVRTDSLKGR-------------RGRL--------------PSKPKQPPDA 359 C VGM+K +R D GR RG + P K+ Sbjct: 245 CYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKN 304 Query: 360 SPANLLTS--LVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVI 417 S A LT+ +V A LD+ P +Y P +A + +L L + Sbjct: 305 SLALSLTADQMVSALLDAEPPILYSEYD-------PTRPFSEASMMGLLTNLADRELVHM 357 Query: 418 RKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQ--C 475 WA+++PGF +L+ DQ LLE A+LE+ ++ L +RS GKL+F L+L R Q C Sbjct: 358 INWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKC 417 Query: 476 ARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLI---------TDRHGLQEPRRVEE 526 G + D +LA S + + F CL +++L+ + L+E + Sbjct: 418 VEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHR 477 Query: 527 LQNRIASCLKEHVAAVAG--EPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVP 583 + ++I L H+ A AG Q L++LL L +R + +G++ ++ +K +++VP Sbjct: 478 VLDKITDTL-IHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVP 535 >gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens] Length = 595 Score = 162 bits (411), Expect = 6e-40 Identities = 151/539 (28%), Positives = 230/539 (42%), Gaps = 109/539 (20%) Query: 96 PASASFKFE-----DFQVYGCYPGPLSGPVDEALSSSGSDYYGSP---CSAPSPSTPSFQ 147 P A+++F + QVYG G GP EA + + G P +PSP Sbjct: 55 PEGAAYEFNAAAAANAQVYG-QTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHP 113 Query: 148 PPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPSLAQSPL 207 PPQLSP+ L+ +Q+P ++ + P+G + A P Sbjct: 114 PPQLSPF---------------LQPHGQQVP----------YYLENEPSGYTVREAGPPA 148 Query: 208 KLFPSQATHQLGEGESYSMPTAFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGSEGR- 266 P+ + G E + T+ K E R Sbjct: 149 FYRPNSDNRRQGGRERLAS------------------------TNDKGSMAMESAKETRY 184 Query: 267 CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQK 326 CAVC D AS HYGV +CEGCK FFKR++Q + Y+C A C +DK RR CQ CR +K Sbjct: 185 CAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRK 244 Query: 327 CLAVGMVKEVVRTDSLKGR-------------RGRL--------------PSKPKQPPDA 359 C VGM+K +R D GR RG + P K+ Sbjct: 245 CYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKN 304 Query: 360 SPANLLTS--LVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVI 417 S A LT+ +V A LD+ P +Y P +A + +L L + Sbjct: 305 SLALSLTADQMVSALLDAEPPILYSEYD-------PTRPFSEASMMGLLTNLADRELVHM 357 Query: 418 RKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQ--C 475 WA+++PGF +L+ DQ LLE A+LE+ ++ L +RS GKL+F L+L R Q C Sbjct: 358 INWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKC 417 Query: 476 ARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLI---------TDRHGLQEPRRVEE 526 G + D +LA S + + F CL +++L+ + L+E + Sbjct: 418 VEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHR 477 Query: 527 LQNRIASCLKEHVAAVAG--EPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVP 583 + ++I L H+ A AG Q L++LL L +R + +G++ ++ +K +++VP Sbjct: 478 VLDKITDTL-IHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVP 535 >gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens] Length = 595 Score = 162 bits (411), Expect = 6e-40 Identities = 151/539 (28%), Positives = 230/539 (42%), Gaps = 109/539 (20%) Query: 96 PASASFKFE-----DFQVYGCYPGPLSGPVDEALSSSGSDYYGSP---CSAPSPSTPSFQ 147 P A+++F + QVYG G GP EA + + G P +PSP Sbjct: 55 PEGAAYEFNAAAAANAQVYG-QTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHP 113 Query: 148 PPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPSLAQSPL 207 PPQLSP+ L+ +Q+P ++ + P+G + A P Sbjct: 114 PPQLSPF---------------LQPHGQQVP----------YYLENEPSGYTVREAGPPA 148 Query: 208 KLFPSQATHQLGEGESYSMPTAFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGSEGR- 266 P+ + G E + T+ K E R Sbjct: 149 FYRPNSDNRRQGGRERLAS------------------------TNDKGSMAMESAKETRY 184 Query: 267 CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQK 326 CAVC D AS HYGV +CEGCK FFKR++Q + Y+C A C +DK RR CQ CR +K Sbjct: 185 CAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRK 244 Query: 327 CLAVGMVKEVVRTDSLKGR-------------RGRL--------------PSKPKQPPDA 359 C VGM+K +R D GR RG + P K+ Sbjct: 245 CYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKN 304 Query: 360 SPANLLTS--LVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVI 417 S A LT+ +V A LD+ P +Y P +A + +L L + Sbjct: 305 SLALSLTADQMVSALLDAEPPILYSEYD-------PTRPFSEASMMGLLTNLADRELVHM 357 Query: 418 RKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQ--C 475 WA+++PGF +L+ DQ LLE A+LE+ ++ L +RS GKL+F L+L R Q C Sbjct: 358 INWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKC 417 Query: 476 ARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLI---------TDRHGLQEPRRVEE 526 G + D +LA S + + F CL +++L+ + L+E + Sbjct: 418 VEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHR 477 Query: 527 LQNRIASCLKEHVAAVAG--EPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVP 583 + ++I L H+ A AG Q L++LL L +R + +G++ ++ +K +++VP Sbjct: 478 VLDKITDTL-IHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVP 535 >gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens] Length = 595 Score = 162 bits (411), Expect = 6e-40 Identities = 151/539 (28%), Positives = 230/539 (42%), Gaps = 109/539 (20%) Query: 96 PASASFKFE-----DFQVYGCYPGPLSGPVDEALSSSGSDYYGSP---CSAPSPSTPSFQ 147 P A+++F + QVYG G GP EA + + G P +PSP Sbjct: 55 PEGAAYEFNAAAAANAQVYG-QTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHP 113 Query: 148 PPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPSLAQSPL 207 PPQLSP+ L+ +Q+P ++ + P+G + A P Sbjct: 114 PPQLSPF---------------LQPHGQQVP----------YYLENEPSGYTVREAGPPA 148 Query: 208 KLFPSQATHQLGEGESYSMPTAFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGSEGR- 266 P+ + G E + T+ K E R Sbjct: 149 FYRPNSDNRRQGGRERLAS------------------------TNDKGSMAMESAKETRY 184 Query: 267 CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQK 326 CAVC D AS HYGV +CEGCK FFKR++Q + Y+C A C +DK RR CQ CR +K Sbjct: 185 CAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRK 244 Query: 327 CLAVGMVKEVVRTDSLKGR-------------RGRL--------------PSKPKQPPDA 359 C VGM+K +R D GR RG + P K+ Sbjct: 245 CYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKN 304 Query: 360 SPANLLTS--LVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVI 417 S A LT+ +V A LD+ P +Y P +A + +L L + Sbjct: 305 SLALSLTADQMVSALLDAEPPILYSEYD-------PTRPFSEASMMGLLTNLADRELVHM 357 Query: 418 RKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQ--C 475 WA+++PGF +L+ DQ LLE A+LE+ ++ L +RS GKL+F L+L R Q C Sbjct: 358 INWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKC 417 Query: 476 ARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLI---------TDRHGLQEPRRVEE 526 G + D +LA S + + F CL +++L+ + L+E + Sbjct: 418 VEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHR 477 Query: 527 LQNRIASCLKEHVAAVAG--EPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVP 583 + ++I L H+ A AG Q L++LL L +R + +G++ ++ +K +++VP Sbjct: 478 VLDKITDTL-IHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVP 535 >gi|194294517 nuclear receptor subfamily 1, group H, member 3 isoform a [Homo sapiens] Length = 447 Score = 158 bits (399), Expect = 2e-38 Identities = 126/424 (29%), Positives = 199/424 (46%), Gaps = 31/424 (7%) Query: 185 QPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPHLEGSG 244 +P A + S G S + + ++ P A G G + PTA L P E + Sbjct: 22 KPGAQDASSQAQGGSSCILREEARM-PHSAGGTAGVGLEAAEPTAL--LTRAEPPSEPTE 78 Query: 245 ILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICL 304 I P K + G+E C+VCGD AS HY V +CEGCKGFF+R+V K A YIC Sbjct: 79 I--RPQKRKKGPAPKMLGNE-LCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHYICH 135 Query: 305 ANKDCPVDKRRRNRCQFCRFQKCLAVGM------------VKEVVRTDSLKGRRGRLPSK 352 + CP+D R +CQ CR +KC GM +K++ R + + LP + Sbjct: 136 SGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSLPPR 195 Query: 353 PKQPPDASP------ANLLTSLVRA--HLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQ 404 PP P ++ LV A + + +L + + PH + Sbjct: 196 ASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQQRFA 255 Query: 405 QFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIF 464 F +L S++ I +A+++PGF +LS DQ LL+++ +E+ +L + R PG + F Sbjct: 256 HFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITF 315 Query: 465 CSGLVLHRLQCARG--FGDWIDSILAFSRSLHSLLVDVPAFACLSAL-VLITDRHGLQEP 521 +R A+ ++I+ I FSR+++ L ++ FA L A+ + DR +Q+ Sbjct: 316 LKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQ 375 Query: 522 RRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDL 581 +VE LQ+ L +V+ P R+L KL LRTL + +++F L+L+D Sbjct: 376 LQVERLQHTYVEALHAYVS--IHHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDK 433 Query: 582 VPPP 585 PP Sbjct: 434 KLPP 437 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.135 0.417 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,719,744 Number of Sequences: 37866 Number of extensions: 1724455 Number of successful extensions: 11947 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 167 Number of HSP's successfully gapped in prelim test: 585 Number of HSP's that attempted gapping in prelim test: 9345 Number of HSP's gapped (non-prelim): 2362 length of query: 598 length of database: 18,247,518 effective HSP length: 108 effective length of query: 490 effective length of database: 14,157,990 effective search space: 6937415100 effective search space used: 6937415100 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.