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Search of human proteins with 27886590
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27886590 PTK2B protein tyrosine kinase 2 beta isoform a
[Homo sapiens]
(1009 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27886590 PTK2B protein tyrosine kinase 2 beta isoform a [Homo... 2043 0.0
gi|27886586 PTK2B protein tyrosine kinase 2 beta isoform a [Homo... 2043 0.0
gi|27886584 PTK2B protein tyrosine kinase 2 beta isoform a [Homo... 2043 0.0
gi|27886588 PTK2B protein tyrosine kinase 2 beta isoform b [Homo... 1933 0.0
gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens] 824 0.0
gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens] 824 0.0
gi|119964721 fer (fps/fes related) tyrosine kinase [Homo sapiens] 232 1e-60
gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a... 215 1e-55
gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b... 215 1e-55
gi|4885215 v-erb-a erythroblastic leukemia viral oncogene homolo... 214 3e-55
gi|110825958 v-erb-a erythroblastic leukemia viral oncogene homo... 213 6e-55
gi|153266778 arg tyrosine kinase isoform c [Homo sapiens] 211 3e-54
gi|6382062 arg tyrosine kinase isoform b [Homo sapiens] 211 3e-54
gi|209862778 arg tyrosine kinase isoform e [Homo sapiens] 211 3e-54
gi|209862772 arg tyrosine kinase isoform d [Homo sapiens] 211 3e-54
gi|153266757 arg tyrosine kinase isoform a [Homo sapiens] 211 3e-54
gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens] 211 3e-54
gi|4557665 insulin-like growth factor 1 receptor precursor [Homo... 208 2e-53
gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens] 206 7e-53
gi|54792098 erbB-2 isoform b [Homo sapiens] 204 3e-52
gi|54792096 erbB-2 isoform a [Homo sapiens] 204 3e-52
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap... 204 3e-52
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi... 204 3e-52
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap... 204 3e-52
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap... 204 3e-52
gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapi... 204 3e-52
gi|219842236 feline sarcoma oncogene isoform 4 [Homo sapiens] 204 4e-52
gi|219842233 feline sarcoma oncogene isoform 3 [Homo sapiens] 204 4e-52
gi|219842230 feline sarcoma oncogene isoform 2 [Homo sapiens] 204 4e-52
gi|4503687 feline sarcoma oncogene isoform 1 [Homo sapiens] 204 4e-52
>gi|27886590 PTK2B protein tyrosine kinase 2 beta isoform a [Homo
sapiens]
Length = 1009
Score = 2043 bits (5292), Expect = 0.0
Identities = 1009/1009 (100%), Positives = 1009/1009 (100%)
Query: 1 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK 60
MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
Sbjct: 1 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK 60
Query: 61 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC 120
CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
Sbjct: 61 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC 120
Query: 121 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC 180
LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
Sbjct: 121 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC 180
Query: 181 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS 240
LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
Sbjct: 181 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS 240
Query: 241 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA 300
LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
Sbjct: 241 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA 300
Query: 301 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG 360
EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
Sbjct: 301 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG 360
Query: 361 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI 420
SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
Sbjct: 361 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI 420
Query: 421 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN 480
AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
Sbjct: 421 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN 480
Query: 481 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL 540
LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
Sbjct: 481 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL 540
Query: 541 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR 600
ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
Sbjct: 541 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR 600
Query: 601 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR 660
RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
Sbjct: 601 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR 660
Query: 661 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP 720
CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
Sbjct: 661 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP 720
Query: 721 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR 780
KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
Sbjct: 721 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR 780
Query: 781 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP 840
EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP
Sbjct: 781 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP 840
Query: 841 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ 900
LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
Sbjct: 841 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ 900
Query: 901 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA 960
LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
Sbjct: 901 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA 960
Query: 961 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE 1009
QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
Sbjct: 961 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE 1009
>gi|27886586 PTK2B protein tyrosine kinase 2 beta isoform a [Homo
sapiens]
Length = 1009
Score = 2043 bits (5292), Expect = 0.0
Identities = 1009/1009 (100%), Positives = 1009/1009 (100%)
Query: 1 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK 60
MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
Sbjct: 1 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK 60
Query: 61 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC 120
CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
Sbjct: 61 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC 120
Query: 121 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC 180
LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
Sbjct: 121 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC 180
Query: 181 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS 240
LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
Sbjct: 181 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS 240
Query: 241 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA 300
LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
Sbjct: 241 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA 300
Query: 301 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG 360
EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
Sbjct: 301 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG 360
Query: 361 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI 420
SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
Sbjct: 361 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI 420
Query: 421 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN 480
AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
Sbjct: 421 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN 480
Query: 481 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL 540
LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
Sbjct: 481 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL 540
Query: 541 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR 600
ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
Sbjct: 541 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR 600
Query: 601 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR 660
RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
Sbjct: 601 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR 660
Query: 661 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP 720
CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
Sbjct: 661 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP 720
Query: 721 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR 780
KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
Sbjct: 721 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR 780
Query: 781 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP 840
EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP
Sbjct: 781 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP 840
Query: 841 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ 900
LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
Sbjct: 841 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ 900
Query: 901 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA 960
LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
Sbjct: 901 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA 960
Query: 961 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE 1009
QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
Sbjct: 961 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE 1009
>gi|27886584 PTK2B protein tyrosine kinase 2 beta isoform a [Homo
sapiens]
Length = 1009
Score = 2043 bits (5292), Expect = 0.0
Identities = 1009/1009 (100%), Positives = 1009/1009 (100%)
Query: 1 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK 60
MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
Sbjct: 1 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK 60
Query: 61 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC 120
CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
Sbjct: 61 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC 120
Query: 121 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC 180
LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
Sbjct: 121 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC 180
Query: 181 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS 240
LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
Sbjct: 181 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS 240
Query: 241 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA 300
LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
Sbjct: 241 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA 300
Query: 301 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG 360
EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
Sbjct: 301 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG 360
Query: 361 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI 420
SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
Sbjct: 361 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI 420
Query: 421 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN 480
AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
Sbjct: 421 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN 480
Query: 481 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL 540
LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
Sbjct: 481 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL 540
Query: 541 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR 600
ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
Sbjct: 541 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR 600
Query: 601 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR 660
RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
Sbjct: 601 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR 660
Query: 661 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP 720
CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
Sbjct: 661 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP 720
Query: 721 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR 780
KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
Sbjct: 721 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR 780
Query: 781 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP 840
EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP
Sbjct: 781 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP 840
Query: 841 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ 900
LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
Sbjct: 841 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ 900
Query: 901 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA 960
LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
Sbjct: 901 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA 960
Query: 961 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE 1009
QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
Sbjct: 961 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE 1009
>gi|27886588 PTK2B protein tyrosine kinase 2 beta isoform b [Homo
sapiens]
Length = 967
Score = 1933 bits (5007), Expect = 0.0
Identities = 967/1009 (95%), Positives = 967/1009 (95%), Gaps = 42/1009 (4%)
Query: 1 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK 60
MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
Sbjct: 1 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK 60
Query: 61 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC 120
CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
Sbjct: 61 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC 120
Query: 121 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC 180
LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
Sbjct: 121 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC 180
Query: 181 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS 240
LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
Sbjct: 181 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS 240
Query: 241 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA 300
LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
Sbjct: 241 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA 300
Query: 301 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG 360
EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
Sbjct: 301 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG 360
Query: 361 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI 420
SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
Sbjct: 361 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI 420
Query: 421 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN 480
AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
Sbjct: 421 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN 480
Query: 481 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL 540
LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
Sbjct: 481 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL 540
Query: 541 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR 600
ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
Sbjct: 541 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR 600
Query: 601 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR 660
RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
Sbjct: 601 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR 660
Query: 661 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP 720
CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
Sbjct: 661 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP 720
Query: 721 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR 780
KYRPPPQTNLLAPKLQFQ
Sbjct: 721 KYRPPPQTNLLAPKLQFQ------------------------------------------ 738
Query: 781 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP 840
EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP
Sbjct: 739 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP 798
Query: 841 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ 900
LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
Sbjct: 799 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ 858
Query: 901 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA 960
LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
Sbjct: 859 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA 918
Query: 961 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE 1009
QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
Sbjct: 919 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE 967
>gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]
Length = 1074
Score = 824 bits (2128), Expect = 0.0
Identities = 473/1022 (46%), Positives = 637/1022 (62%), Gaps = 74/1022 (7%)
Query: 39 RILKVCFY--SNSFNPGKNFKLVKCTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKH 96
R+LKV Y SNS P +++ T++R II I+ S ++ + CYG RL H
Sbjct: 57 RVLKVFHYFESNS-EPTTWASIIRHGDATDVRGIIQKIVDSHKV----KHVACYGFRLSH 111
Query: 97 MKSDEIHWLHPQMTVGEVQDKYECLHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQ 156
++S+E+HWLH M V V++KYE H EW+Y+L+IRYLP+ F+ ED+ TL +FYQ
Sbjct: 112 LRSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQFTEDKPTLNFFYQ 171
Query: 157 QLRNDYMQRYASKVSEGMALQLGCLELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPK 216
Q+++DYM A +V + +AL+LGCLE+RR + +M NAL+KKSN+E+LEK+VGL FFPK
Sbjct: 172 QVKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPK 231
Query: 217 QMQENLKPKQFRKMIQQTFQQYASLREEECVMKFFNTLAGFANIDQETYRCELIQGWNIT 276
+ +++K K RK+IQQTF+Q+A+L EE ++KFF L+ D+E ++C L W I+
Sbjct: 232 SLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCALGSSWIIS 291
Query: 277 VDLVIGPK-GIRQLTSQDAKPTCLAEFKQIRSIRCLPLEEG--QAVLQLGIEGAPQALSI 333
V+L IGP+ GI LT + PT LA+F Q+++I+ E+ + +LQL I GAP+ L++
Sbjct: 292 VELAIGPEEGISYLTDKGCNPTHLADFTQVQTIQYSNSEDKDRKGMLQLKIAGAPEPLTV 351
Query: 334 KTSSLAEAENMADLIDGYCRLQGEHQGSLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSE 393
SL AENMADLIDGYCRL S II P+K+GE+ +LP IP L ++ +
Sbjct: 352 TAPSLTIAENMADLIDGYCRLVNGTSQSFIIRPQKEGER--ALPSIPKLANSEKQGMRTH 409
Query: 394 SCSI-ESDIYAEIPDE--TLRRPGGPQYGIAREDVVLNRILGEGFFGEVYEGVYTNHKGE 450
+ S+ E+D YAEI DE T P Y I RE + L R +GEG FG+V++G+Y + +
Sbjct: 410 AVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENP 469
Query: 451 KINVAVKTCKKDCTLDN-KEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGE 509
+ VA+KTCK +CT D+ +EKF+ EA+ M+ DHPHIVKLIG+I E P WIIMEL GE
Sbjct: 470 ALAVAIKTCK-NCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGE 528
Query: 510 LGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFG 569
L +L+ K SL + +L+LY+ Q+ A+AYLES VHRDIA RN+LV+S +CVKLGDFG
Sbjct: 529 LRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFG 588
Query: 570 LSRYIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWL 629
LSRY+ED YYKAS +LPIKWM+PESINFRRFT+ASDVWMF VCMWEIL G +PF +
Sbjct: 589 LSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGV 648
Query: 630 ENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQMEKDI 689
+N DVIG +E G+RLP P CPP LY+LMT+CW YDPS RPRFTEL LS + + EK
Sbjct: 649 KNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEK-- 706
Query: 690 AMEQER---NARYRTPKILEPTAFQEPPPKPSRPKYRPPPQTNLLAPKLQ-------FQV 739
A ++ER +R + + E PPKPSRP Y P + P Q +QV
Sbjct: 707 AQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQV 766
Query: 740 PEGLCASSPTLTSPMEYPSPVNSLHTPPL--HRHNVFKRHSMREEDFIQPSSREEAQQLW 797
+ T + YP + L HR ED R Q L
Sbjct: 767 SGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVL- 825
Query: 798 EAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKS----------PLTPE--- 844
M + L +QQ++M ED +WL +EE+ L P V ++ S P+ +
Sbjct: 826 --PTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIY 883
Query: 845 KEVGYLEFTGPPQKPPRLGAQ---------------------------SIQPTANLDRTD 877
+ VG + PP+KPPR GA S PTANLDR++
Sbjct: 884 QPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSYNEGVKLQPQEISPPPTANLDRSN 943
Query: 878 DLVYLNVMELVRAVLELKNELCQLPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRT 937
D VY NV LV+AV+E+ +++ PPE YV +VK VGL LR L+ +VD+ +P LP+S+
Sbjct: 944 DKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHR 1003
Query: 938 EIEGTQKLLNKDLAELINKMRLAQQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQA 997
EIE QKLLN DL ELINKM+LAQQ +TSL +E K+QMLTA+H LAVDAKNLLD +DQA
Sbjct: 1004 EIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQA 1063
Query: 998 KV 999
++
Sbjct: 1064 RL 1065
>gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]
Length = 1052
Score = 824 bits (2128), Expect = 0.0
Identities = 473/1022 (46%), Positives = 637/1022 (62%), Gaps = 74/1022 (7%)
Query: 39 RILKVCFY--SNSFNPGKNFKLVKCTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKH 96
R+LKV Y SNS P +++ T++R II I+ S ++ + CYG RL H
Sbjct: 35 RVLKVFHYFESNS-EPTTWASIIRHGDATDVRGIIQKIVDSHKV----KHVACYGFRLSH 89
Query: 97 MKSDEIHWLHPQMTVGEVQDKYECLHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQ 156
++S+E+HWLH M V V++KYE H EW+Y+L+IRYLP+ F+ ED+ TL +FYQ
Sbjct: 90 LRSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQFTEDKPTLNFFYQ 149
Query: 157 QLRNDYMQRYASKVSEGMALQLGCLELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPK 216
Q+++DYM A +V + +AL+LGCLE+RR + +M NAL+KKSN+E+LEK+VGL FFPK
Sbjct: 150 QVKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPK 209
Query: 217 QMQENLKPKQFRKMIQQTFQQYASLREEECVMKFFNTLAGFANIDQETYRCELIQGWNIT 276
+ +++K K RK+IQQTF+Q+A+L EE ++KFF L+ D+E ++C L W I+
Sbjct: 210 SLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCALGSSWIIS 269
Query: 277 VDLVIGPK-GIRQLTSQDAKPTCLAEFKQIRSIRCLPLEEG--QAVLQLGIEGAPQALSI 333
V+L IGP+ GI LT + PT LA+F Q+++I+ E+ + +LQL I GAP+ L++
Sbjct: 270 VELAIGPEEGISYLTDKGCNPTHLADFTQVQTIQYSNSEDKDRKGMLQLKIAGAPEPLTV 329
Query: 334 KTSSLAEAENMADLIDGYCRLQGEHQGSLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSE 393
SL AENMADLIDGYCRL S II P+K+GE+ +LP IP L ++ +
Sbjct: 330 TAPSLTIAENMADLIDGYCRLVNGTSQSFIIRPQKEGER--ALPSIPKLANSEKQGMRTH 387
Query: 394 SCSI-ESDIYAEIPDE--TLRRPGGPQYGIAREDVVLNRILGEGFFGEVYEGVYTNHKGE 450
+ S+ E+D YAEI DE T P Y I RE + L R +GEG FG+V++G+Y + +
Sbjct: 388 AVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENP 447
Query: 451 KINVAVKTCKKDCTLDN-KEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGE 509
+ VA+KTCK +CT D+ +EKF+ EA+ M+ DHPHIVKLIG+I E P WIIMEL GE
Sbjct: 448 ALAVAIKTCK-NCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGE 506
Query: 510 LGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFG 569
L +L+ K SL + +L+LY+ Q+ A+AYLES VHRDIA RN+LV+S +CVKLGDFG
Sbjct: 507 LRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFG 566
Query: 570 LSRYIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWL 629
LSRY+ED YYKAS +LPIKWM+PESINFRRFT+ASDVWMF VCMWEIL G +PF +
Sbjct: 567 LSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGV 626
Query: 630 ENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQMEKDI 689
+N DVIG +E G+RLP P CPP LY+LMT+CW YDPS RPRFTEL LS + + EK
Sbjct: 627 KNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEK-- 684
Query: 690 AMEQER---NARYRTPKILEPTAFQEPPPKPSRPKYRPPPQTNLLAPKLQ-------FQV 739
A ++ER +R + + E PPKPSRP Y P + P Q +QV
Sbjct: 685 AQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQV 744
Query: 740 PEGLCASSPTLTSPMEYPSPVNSLHTPPL--HRHNVFKRHSMREEDFIQPSSREEAQQLW 797
+ T + YP + L HR ED R Q L
Sbjct: 745 SGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVL- 803
Query: 798 EAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKS----------PLTPE--- 844
M + L +QQ++M ED +WL +EE+ L P V ++ S P+ +
Sbjct: 804 --PTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIY 861
Query: 845 KEVGYLEFTGPPQKPPRLGAQ---------------------------SIQPTANLDRTD 877
+ VG + PP+KPPR GA S PTANLDR++
Sbjct: 862 QPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSYNEGVKLQPQEISPPPTANLDRSN 921
Query: 878 DLVYLNVMELVRAVLELKNELCQLPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRT 937
D VY NV LV+AV+E+ +++ PPE YV +VK VGL LR L+ +VD+ +P LP+S+
Sbjct: 922 DKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHR 981
Query: 938 EIEGTQKLLNKDLAELINKMRLAQQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQA 997
EIE QKLLN DL ELINKM+LAQQ +TSL +E K+QMLTA+H LAVDAKNLLD +DQA
Sbjct: 982 EIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQA 1041
Query: 998 KV 999
++
Sbjct: 1042 RL 1043
>gi|119964721 fer (fps/fes related) tyrosine kinase [Homo sapiens]
Length = 822
Score = 232 bits (592), Expect = 1e-60
Identities = 113/264 (42%), Positives = 168/264 (63%), Gaps = 5/264 (1%)
Query: 413 PGGPQYGIAREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFM 472
P ++ ++ EDV+L +LG+G FGEVY+G +K +VAVKTCK+D + K KF+
Sbjct: 551 PKDKKWILSHEDVILGELLGKGNFGEVYKGTLK----DKTSVAVKTCKEDLPQELKIKFL 606
Query: 473 SEAVIMKNLDHPHIVKLIGII-EEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSL 531
EA I+K DHP+IVKLIG+ + +P +IIMEL G+ +L R K+ LK+ LV +SL
Sbjct: 607 QEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQLVKFSL 666
Query: 532 QICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKW 591
M YLES NC+HRD+A RN LV +K+ DFG+SR + Y + + ++PIKW
Sbjct: 667 DAAAGMLYLESKNCIHRDLAARNCLVGENNVLKISDFGMSRQEDGGVYSSSGLKQIPIKW 726
Query: 592 MSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCP 651
+PE++N+ R+++ SDVW F + +WE S G P+ + N+ +E+G R+ P CP
Sbjct: 727 TAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQHCP 786
Query: 652 PVLYTLMTRCWDYDPSDRPRFTEL 675
+ +M +CWDY P +RP+F+EL
Sbjct: 787 EDISKIMMKCWDYKPENRPKFSEL 810
>gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a
[Homo sapiens]
Length = 1130
Score = 215 bits (548), Expect = 1e-55
Identities = 116/303 (38%), Positives = 174/303 (57%), Gaps = 8/303 (2%)
Query: 413 PGGPQYGIAREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFM 472
P ++ + R D+ + LG G +GEVYEGV+ + + VAVKT K+D E+F+
Sbjct: 230 PNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYS---LTVAVKTLKEDTM--EVEEFL 284
Query: 473 SEAVIMKNLDHPHIVKLIGIIEEEPT-WIIMELYPYGELGHYL-ERNKNSLKVLTLVLYS 530
EA +MK + HP++V+L+G+ EP +II E YG L YL E N+ + + L+ +
Sbjct: 285 KEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMA 344
Query: 531 LQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIK 590
QI AM YLE N +HRD+A RN LV VK+ DFGLSR + + Y + + PIK
Sbjct: 345 TQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIK 404
Query: 591 WMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLC 650
W +PES+ + +F+ SDVW F V +WEI ++G P+ ++ V +LEK R+ +P+ C
Sbjct: 405 WTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGC 464
Query: 651 PPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAF 710
P +Y LM CW ++PSDRP F E+ + ++Q E I+ E E+ + + T
Sbjct: 465 PEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQ-ESSISDEVEKELGKQGVRGAVSTLL 523
Query: 711 QEP 713
Q P
Sbjct: 524 QAP 526
>gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b
[Homo sapiens]
Length = 1149
Score = 215 bits (548), Expect = 1e-55
Identities = 116/303 (38%), Positives = 174/303 (57%), Gaps = 8/303 (2%)
Query: 413 PGGPQYGIAREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFM 472
P ++ + R D+ + LG G +GEVYEGV+ + + VAVKT K+D E+F+
Sbjct: 249 PNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYS---LTVAVKTLKEDTM--EVEEFL 303
Query: 473 SEAVIMKNLDHPHIVKLIGIIEEEPT-WIIMELYPYGELGHYL-ERNKNSLKVLTLVLYS 530
EA +MK + HP++V+L+G+ EP +II E YG L YL E N+ + + L+ +
Sbjct: 304 KEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMA 363
Query: 531 LQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIK 590
QI AM YLE N +HRD+A RN LV VK+ DFGLSR + + Y + + PIK
Sbjct: 364 TQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIK 423
Query: 591 WMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLC 650
W +PES+ + +F+ SDVW F V +WEI ++G P+ ++ V +LEK R+ +P+ C
Sbjct: 424 WTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGC 483
Query: 651 PPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAF 710
P +Y LM CW ++PSDRP F E+ + ++Q E I+ E E+ + + T
Sbjct: 484 PEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQ-ESSISDEVEKELGKQGVRGAVSTLL 542
Query: 711 QEP 713
Q P
Sbjct: 543 QAP 545
>gi|4885215 v-erb-a erythroblastic leukemia viral oncogene homolog 4
isoform JM-a/CVT-1 precursor [Homo sapiens]
Length = 1308
Score = 214 bits (546), Expect = 3e-55
Identities = 125/376 (33%), Positives = 203/376 (53%), Gaps = 40/376 (10%)
Query: 429 RILGEGFFGEVYEGVYTNHKGE--KINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHI 486
++LG G FG VY+G++ +GE KI VA+K + +FM EA+IM ++DHPH+
Sbjct: 722 KVLGSGAFGTVYKGIWVP-EGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHL 780
Query: 487 VKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCV 546
V+L+G+ ++ +L P+G L Y+ +K+++ L+ + +QI K M YLE V
Sbjct: 781 VRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV 840
Query: 547 HRDIAVRNILVASPECVKLGDFGLSRYIE-DEDYYKASVTRLPIKWMSPESINFRRFTTA 605
HRD+A RN+LV SP VK+ DFGL+R +E DE Y A ++PIKWM+ E I++R+FT
Sbjct: 841 HRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQ 900
Query: 606 SDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYD 665
SDVW + V +WE+++FG +P+ + +++ +LEKG+RLP+P +C +Y +M +CW D
Sbjct: 901 SDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMID 960
Query: 666 PSDRPRFTELVCSLSDV-----------------------YQMEKDIAMEQERNARYRTP 702
RP+F EL S + + +++ E++
Sbjct: 961 ADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAE 1020
Query: 703 KILEPTAFQEPPP----------KPSRPKYRPPPQTNLLAPKLQFQVPEGLCASSPTLTS 752
+ L P AF PPP S + PPP ++ QF +G A+ ++
Sbjct: 1021 EYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGN-QFVYRDGGFAAEQGVSV 1079
Query: 753 PMEYPSPVNSLHTPPL 768
P Y +P +++ P+
Sbjct: 1080 P--YRAPTSTIPEAPV 1093
>gi|110825958 v-erb-a erythroblastic leukemia viral oncogene homolog
4 isoform JM-a/CVT-2 precursor [Homo sapiens]
Length = 1292
Score = 213 bits (543), Expect = 6e-55
Identities = 105/255 (41%), Positives = 163/255 (63%), Gaps = 4/255 (1%)
Query: 429 RILGEGFFGEVYEGVYTNHKGE--KINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHI 486
++LG G FG VY+G++ +GE KI VA+K + +FM EA+IM ++DHPH+
Sbjct: 722 KVLGSGAFGTVYKGIWVP-EGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHL 780
Query: 487 VKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCV 546
V+L+G+ ++ +L P+G L Y+ +K+++ L+ + +QI K M YLE V
Sbjct: 781 VRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV 840
Query: 547 HRDIAVRNILVASPECVKLGDFGLSRYIE-DEDYYKASVTRLPIKWMSPESINFRRFTTA 605
HRD+A RN+LV SP VK+ DFGL+R +E DE Y A ++PIKWM+ E I++R+FT
Sbjct: 841 HRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQ 900
Query: 606 SDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYD 665
SDVW + V +WE+++FG +P+ + +++ +LEKG+RLP+P +C +Y +M +CW D
Sbjct: 901 SDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMID 960
Query: 666 PSDRPRFTELVCSLS 680
RP+F EL S
Sbjct: 961 ADSRPKFKELAAEFS 975
>gi|153266778 arg tyrosine kinase isoform c [Homo sapiens]
Length = 1167
Score = 211 bits (537), Expect = 3e-54
Identities = 107/260 (41%), Positives = 157/260 (60%), Gaps = 7/260 (2%)
Query: 417 QYGIAREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAV 476
++ + R D+ + LG G +GEVY GV+ + + VAVKT K+D E+F+ EA
Sbjct: 265 KWEMERTDITMKHKLGGGQYGEVYVGVWKKYS---LTVAVKTLKEDTM--EVEEFLKEAA 319
Query: 477 IMKNLDHPHIVKLIGIIE-EEPTWIIMELYPYGELGHYL-ERNKNSLKVLTLVLYSLQIC 534
+MK + HP++V+L+G+ E P +I+ E PYG L YL E N+ + + L+ + QI
Sbjct: 320 VMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQIS 379
Query: 535 KAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSP 594
AM YLE N +HRD+A RN LV VK+ DFGLSR + + Y + + PIKW +P
Sbjct: 380 SAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAP 439
Query: 595 ESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVL 654
ES+ + F+ SDVW F V +WEI ++G P+ ++ V +LEKG R+ +P+ CPP +
Sbjct: 440 ESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKV 499
Query: 655 YTLMTRCWDYDPSDRPRFTE 674
Y LM CW + P+DRP F E
Sbjct: 500 YELMRACWKWSPADRPSFAE 519
>gi|6382062 arg tyrosine kinase isoform b [Homo sapiens]
Length = 1182
Score = 211 bits (537), Expect = 3e-54
Identities = 107/260 (41%), Positives = 157/260 (60%), Gaps = 7/260 (2%)
Query: 417 QYGIAREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAV 476
++ + R D+ + LG G +GEVY GV+ + + VAVKT K+D E+F+ EA
Sbjct: 280 KWEMERTDITMKHKLGGGQYGEVYVGVWKKYS---LTVAVKTLKEDTM--EVEEFLKEAA 334
Query: 477 IMKNLDHPHIVKLIGIIE-EEPTWIIMELYPYGELGHYL-ERNKNSLKVLTLVLYSLQIC 534
+MK + HP++V+L+G+ E P +I+ E PYG L YL E N+ + + L+ + QI
Sbjct: 335 VMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQIS 394
Query: 535 KAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSP 594
AM YLE N +HRD+A RN LV VK+ DFGLSR + + Y + + PIKW +P
Sbjct: 395 SAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAP 454
Query: 595 ESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVL 654
ES+ + F+ SDVW F V +WEI ++G P+ ++ V +LEKG R+ +P+ CPP +
Sbjct: 455 ESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKV 514
Query: 655 YTLMTRCWDYDPSDRPRFTE 674
Y LM CW + P+DRP F E
Sbjct: 515 YELMRACWKWSPADRPSFAE 534
>gi|209862778 arg tyrosine kinase isoform e [Homo sapiens]
Length = 542
Score = 211 bits (537), Expect = 3e-54
Identities = 107/260 (41%), Positives = 157/260 (60%), Gaps = 7/260 (2%)
Query: 417 QYGIAREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAV 476
++ + R D+ + LG G +GEVY GV+ + + VAVKT K+D E+F+ EA
Sbjct: 259 KWEMERTDITMKHKLGGGQYGEVYVGVWKKYS---LTVAVKTLKEDTM--EVEEFLKEAA 313
Query: 477 IMKNLDHPHIVKLIGIIE-EEPTWIIMELYPYGELGHYL-ERNKNSLKVLTLVLYSLQIC 534
+MK + HP++V+L+G+ E P +I+ E PYG L YL E N+ + + L+ + QI
Sbjct: 314 VMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQIS 373
Query: 535 KAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSP 594
AM YLE N +HRD+A RN LV VK+ DFGLSR + + Y + + PIKW +P
Sbjct: 374 SAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAP 433
Query: 595 ESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVL 654
ES+ + F+ SDVW F V +WEI ++G P+ ++ V +LEKG R+ +P+ CPP +
Sbjct: 434 ESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKV 493
Query: 655 YTLMTRCWDYDPSDRPRFTE 674
Y LM CW + P+DRP F E
Sbjct: 494 YELMRACWKWSPADRPSFAE 513
>gi|209862772 arg tyrosine kinase isoform d [Homo sapiens]
Length = 1064
Score = 211 bits (537), Expect = 3e-54
Identities = 107/260 (41%), Positives = 157/260 (60%), Gaps = 7/260 (2%)
Query: 417 QYGIAREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAV 476
++ + R D+ + LG G +GEVY GV+ + + VAVKT K+D E+F+ EA
Sbjct: 265 KWEMERTDITMKHKLGGGQYGEVYVGVWKKYS---LTVAVKTLKEDTM--EVEEFLKEAA 319
Query: 477 IMKNLDHPHIVKLIGIIE-EEPTWIIMELYPYGELGHYL-ERNKNSLKVLTLVLYSLQIC 534
+MK + HP++V+L+G+ E P +I+ E PYG L YL E N+ + + L+ + QI
Sbjct: 320 VMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQIS 379
Query: 535 KAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSP 594
AM YLE N +HRD+A RN LV VK+ DFGLSR + + Y + + PIKW +P
Sbjct: 380 SAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAP 439
Query: 595 ESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVL 654
ES+ + F+ SDVW F V +WEI ++G P+ ++ V +LEKG R+ +P+ CPP +
Sbjct: 440 ESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKV 499
Query: 655 YTLMTRCWDYDPSDRPRFTE 674
Y LM CW + P+DRP F E
Sbjct: 500 YELMRACWKWSPADRPSFAE 519
>gi|153266757 arg tyrosine kinase isoform a [Homo sapiens]
Length = 1146
Score = 211 bits (537), Expect = 3e-54
Identities = 107/260 (41%), Positives = 157/260 (60%), Gaps = 7/260 (2%)
Query: 417 QYGIAREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAV 476
++ + R D+ + LG G +GEVY GV+ + + VAVKT K+D E+F+ EA
Sbjct: 244 KWEMERTDITMKHKLGGGQYGEVYVGVWKKYS---LTVAVKTLKEDTM--EVEEFLKEAA 298
Query: 477 IMKNLDHPHIVKLIGIIE-EEPTWIIMELYPYGELGHYL-ERNKNSLKVLTLVLYSLQIC 534
+MK + HP++V+L+G+ E P +I+ E PYG L YL E N+ + + L+ + QI
Sbjct: 299 VMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQIS 358
Query: 535 KAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSP 594
AM YLE N +HRD+A RN LV VK+ DFGLSR + + Y + + PIKW +P
Sbjct: 359 SAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAP 418
Query: 595 ESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVL 654
ES+ + F+ SDVW F V +WEI ++G P+ ++ V +LEKG R+ +P+ CPP +
Sbjct: 419 ESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKV 478
Query: 655 YTLMTRCWDYDPSDRPRFTE 674
Y LM CW + P+DRP F E
Sbjct: 479 YELMRACWKWSPADRPSFAE 498
>gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]
Length = 984
Score = 211 bits (537), Expect = 3e-54
Identities = 108/260 (41%), Positives = 158/260 (60%), Gaps = 5/260 (1%)
Query: 425 VVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHP 484
V + ++G G FGEVY+G +I VA+KT K + + F+SEA IM DHP
Sbjct: 619 VKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHP 678
Query: 485 HIVKLIGII-EEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESI 543
+I++L G++ + P II E G L +L +N V+ LV I M YL +
Sbjct: 679 NIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLAEM 738
Query: 544 NCVHRDIAVRNILVASPECVKLGDFGLSRYIEDED----YYKASVTRLPIKWMSPESINF 599
N VHRD+A RNILV S K+ DFGLSRY++D+ Y + ++P++W +PE+I +
Sbjct: 739 NYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAY 798
Query: 600 RRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMT 659
R+FT+ASDVW + + MWE++SFG++P++ + N+DVI +E+ RLP P CP L+ LM
Sbjct: 799 RKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLML 858
Query: 660 RCWDYDPSDRPRFTELVCSL 679
CW D + RPRF E+V +L
Sbjct: 859 DCWQKDRNSRPRFAEIVNTL 878
>gi|4557665 insulin-like growth factor 1 receptor precursor [Homo
sapiens]
Length = 1367
Score = 208 bits (530), Expect = 2e-53
Identities = 121/338 (35%), Positives = 192/338 (56%), Gaps = 31/338 (9%)
Query: 399 SDIYAEIPDETLRRPGGPQYGIAREDVVLNRILGEGFFGEVYEGVYTNHKGEK--INVAV 456
+D+Y +PDE + +ARE + ++R LG+G FG VYEGV ++ VA+
Sbjct: 984 ADVY--VPDE---------WEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAI 1032
Query: 457 KTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEE-EPTWIIMELYPYGELGHYLE 515
KT + ++ + +F++EA +MK + H+V+L+G++ + +PT +IMEL G+L YL
Sbjct: 1033 KTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLR 1092
Query: 516 RNKNSLK---------VLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLG 566
+ ++ + ++ + +I MAYL + VHRD+A RN +VA VK+G
Sbjct: 1093 SLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIG 1152
Query: 567 DFGLSRYIEDEDYY-KASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQP 625
DFG++R I + DYY K LP++WMSPES+ FTT SDVW F V +WEI + +QP
Sbjct: 1153 DFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQP 1212
Query: 626 FFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQM 685
+ L N+ V+ + +G L KPD CP +L+ LM CW Y+P RP F E++ S+ + +M
Sbjct: 1213 YQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKE--EM 1270
Query: 686 E---KDIAMEQERNARYRTPK--ILEPTAFQEPPPKPS 718
E ++++ + P+ LEP + P PS
Sbjct: 1271 EPGFREVSFYYSEENKLPEPEELDLEPENMESVPLDPS 1308
>gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]
Length = 526
Score = 206 bits (525), Expect = 7e-53
Identities = 109/265 (41%), Positives = 157/265 (59%), Gaps = 7/265 (2%)
Query: 420 IAREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMK 479
I RE + L + LG G FGEV+ Y H VAVKT K + E F++EA +MK
Sbjct: 257 IPRESLKLEKKLGAGQFGEVWMATYNKHT----KVAVKTMKPGSM--SVEAFLAEANVMK 310
Query: 480 NLDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLT-LVLYSLQICKAMA 538
L H +VKL ++ +EP +II E G L +L+ ++ S + L L+ +S QI + MA
Sbjct: 311 TLQHDKLVKLHAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMA 370
Query: 539 YLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESIN 598
++E N +HRD+ NILV++ K+ DFGL+R IED +Y + PIKW +PE+IN
Sbjct: 371 FIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAIN 430
Query: 599 FRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLM 658
F FT SDVW F + + EI+++G+ P+ + N +VI LE+G R+P+P+ CP LY +M
Sbjct: 431 FGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIM 490
Query: 659 TRCWDYDPSDRPRFTELVCSLSDVY 683
RCW P +RP F + L D Y
Sbjct: 491 MRCWKNRPEERPTFEYIQSVLDDFY 515
>gi|54792098 erbB-2 isoform b [Homo sapiens]
Length = 1225
Score = 204 bits (520), Expect = 3e-52
Identities = 101/254 (39%), Positives = 160/254 (62%), Gaps = 2/254 (0%)
Query: 429 RILGEGFFGEVYEGVYT-NHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIV 487
++LG G FG VY+G++ + + KI VA+K +++ + ++ + EA +M + P++
Sbjct: 694 KVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVS 753
Query: 488 KLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVH 547
+L+GI ++ +L PYG L ++ N+ L L+ + +QI K M+YLE + VH
Sbjct: 754 RLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVH 813
Query: 548 RDIAVRNILVASPECVKLGDFGLSRYIE-DEDYYKASVTRLPIKWMSPESINFRRFTTAS 606
RD+A RN+LV SP VK+ DFGL+R ++ DE Y A ++PIKWM+ ESI RRFT S
Sbjct: 814 RDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQS 873
Query: 607 DVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDP 666
DVW + V +WE+++FG +P+ + +++ +LEKG+RLP+P +C +Y +M +CW D
Sbjct: 874 DVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDS 933
Query: 667 SDRPRFTELVCSLS 680
RPRF ELV S
Sbjct: 934 ECRPRFRELVSEFS 947
>gi|54792096 erbB-2 isoform a [Homo sapiens]
Length = 1255
Score = 204 bits (520), Expect = 3e-52
Identities = 101/254 (39%), Positives = 160/254 (62%), Gaps = 2/254 (0%)
Query: 429 RILGEGFFGEVYEGVYT-NHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIV 487
++LG G FG VY+G++ + + KI VA+K +++ + ++ + EA +M + P++
Sbjct: 724 KVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVS 783
Query: 488 KLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVH 547
+L+GI ++ +L PYG L ++ N+ L L+ + +QI K M+YLE + VH
Sbjct: 784 RLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVH 843
Query: 548 RDIAVRNILVASPECVKLGDFGLSRYIE-DEDYYKASVTRLPIKWMSPESINFRRFTTAS 606
RD+A RN+LV SP VK+ DFGL+R ++ DE Y A ++PIKWM+ ESI RRFT S
Sbjct: 844 RDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQS 903
Query: 607 DVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDP 666
DVW + V +WE+++FG +P+ + +++ +LEKG+RLP+P +C +Y +M +CW D
Sbjct: 904 DVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDS 963
Query: 667 SDRPRFTELVCSLS 680
RPRF ELV S
Sbjct: 964 ECRPRFRELVSEFS 977
>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo
sapiens]
Length = 986
Score = 204 bits (520), Expect = 3e-52
Identities = 106/260 (40%), Positives = 156/260 (60%), Gaps = 5/260 (1%)
Query: 425 VVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHP 484
V + +++G G FGEV G +I VA+KT K T + F+SEA IM DHP
Sbjct: 621 VKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHP 680
Query: 485 HIVKLIGIIEEE-PTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESI 543
+++ L G++ + P II E G L +L +N V+ LV I M YL +
Sbjct: 681 NVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADM 740
Query: 544 NCVHRDIAVRNILVASPECVKLGDFGLSRYIEDED----YYKASVTRLPIKWMSPESINF 599
N VHRD+A RNILV S K+ DFGLSR++ED+ Y A ++PI+W +PE+I +
Sbjct: 741 NYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQY 800
Query: 600 RRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMT 659
R+FT+ASDVW + + MWE++S+G++P++ + N+DVI +E+ RLP P CP L+ LM
Sbjct: 801 RKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLML 860
Query: 660 RCWDYDPSDRPRFTELVCSL 679
CW D + RP+F ++V +L
Sbjct: 861 DCWQKDRNHRPKFGQIVNTL 880
>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
sapiens]
Length = 987
Score = 204 bits (520), Expect = 3e-52
Identities = 106/260 (40%), Positives = 156/260 (60%), Gaps = 5/260 (1%)
Query: 425 VVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHP 484
V + +++G G FGEV G +I VA+KT K T + F+SEA IM DHP
Sbjct: 622 VKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHP 681
Query: 485 HIVKLIGIIEEE-PTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESI 543
+++ L G++ + P II E G L +L +N V+ LV I M YL +
Sbjct: 682 NVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADM 741
Query: 544 NCVHRDIAVRNILVASPECVKLGDFGLSRYIEDED----YYKASVTRLPIKWMSPESINF 599
N VHRD+A RNILV S K+ DFGLSR++ED+ Y A ++PI+W +PE+I +
Sbjct: 742 NYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQY 801
Query: 600 RRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMT 659
R+FT+ASDVW + + MWE++S+G++P++ + N+DVI +E+ RLP P CP L+ LM
Sbjct: 802 RKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLML 861
Query: 660 RCWDYDPSDRPRFTELVCSL 679
CW D + RP+F ++V +L
Sbjct: 862 DCWQKDRNHRPKFGQIVNTL 881
>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo
sapiens]
Length = 1015
Score = 204 bits (519), Expect = 3e-52
Identities = 104/255 (40%), Positives = 153/255 (60%), Gaps = 3/255 (1%)
Query: 425 VVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHP 484
+ + R++G G FGEV G ++ VA+KT K T + F+ EA IM DHP
Sbjct: 653 ITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHP 712
Query: 485 HIVKLIGII-EEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESI 543
+I+ L G++ + +P I+ E G L +L++N V+ LV I M YL +
Sbjct: 713 NIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDM 772
Query: 544 NCVHRDIAVRNILVASPECVKLGDFGLSRYIED--EDYYKASVTRLPIKWMSPESINFRR 601
VHRD+A RNIL+ S K+ DFGLSR +ED E Y ++PI+W +PE+I FR+
Sbjct: 773 GYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRK 832
Query: 602 FTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRC 661
FT+ASDVW + + MWE++S+G++P++ + N+DVI +E+G RLP P CP LY LM C
Sbjct: 833 FTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDC 892
Query: 662 WDYDPSDRPRFTELV 676
W + + RP+F E+V
Sbjct: 893 WQKERNSRPKFDEIV 907
>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo
sapiens]
Length = 1037
Score = 204 bits (519), Expect = 3e-52
Identities = 104/255 (40%), Positives = 153/255 (60%), Gaps = 3/255 (1%)
Query: 425 VVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHP 484
+ + R++G G FGEV G ++ VA+KT K T + F+ EA IM DHP
Sbjct: 675 ITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHP 734
Query: 485 HIVKLIGII-EEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESI 543
+I+ L G++ + +P I+ E G L +L++N V+ LV I M YL +
Sbjct: 735 NIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDM 794
Query: 544 NCVHRDIAVRNILVASPECVKLGDFGLSRYIED--EDYYKASVTRLPIKWMSPESINFRR 601
VHRD+A RNIL+ S K+ DFGLSR +ED E Y ++PI+W +PE+I FR+
Sbjct: 795 GYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRK 854
Query: 602 FTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRC 661
FT+ASDVW + + MWE++S+G++P++ + N+DVI +E+G RLP P CP LY LM C
Sbjct: 855 FTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDC 914
Query: 662 WDYDPSDRPRFTELV 676
W + + RP+F E+V
Sbjct: 915 WQKERNSRPKFDEIV 929
>gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo
sapiens]
Length = 983
Score = 204 bits (519), Expect = 3e-52
Identities = 102/259 (39%), Positives = 159/259 (61%), Gaps = 3/259 (1%)
Query: 424 DVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDH 483
++ +++++G G FGEV G ++I+VA+KT K T + F+ EA IM DH
Sbjct: 620 NISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDH 679
Query: 484 PHIVKLIGII-EEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLES 542
P+I++L G++ + +P I+ E G L +L ++ V+ LV I M YL
Sbjct: 680 PNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSD 739
Query: 543 INCVHRDIAVRNILVASPECVKLGDFGLSRYIED--EDYYKASVTRLPIKWMSPESINFR 600
+ VHRD+A RNIL+ S K+ DFGLSR +ED E Y ++PI+W SPE+I +R
Sbjct: 740 MGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYR 799
Query: 601 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR 660
+FT+ASDVW + + +WE++S+G++P++ + N+DVI +++G RLP P CP LY LM
Sbjct: 800 KFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLD 859
Query: 661 CWDYDPSDRPRFTELVCSL 679
CW D ++RP+F ++V L
Sbjct: 860 CWQKDRNNRPKFEQIVSIL 878
>gi|219842236 feline sarcoma oncogene isoform 4 [Homo sapiens]
Length = 694
Score = 204 bits (518), Expect = 4e-52
Identities = 115/321 (35%), Positives = 182/321 (56%), Gaps = 22/321 (6%)
Query: 367 RKDGEKRNSLPQIPML--NLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGIARED 424
R +GE P IP+L +L + + L++ + ++ +P + ++ + ED
Sbjct: 386 RLEGE---GFPSIPLLIDHLLSTQQPLTKKSGVV--LHRAVPKD--------KWVLNHED 432
Query: 425 VVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHP 484
+VL +G G FGEV+ G + + VAVK+C++ D K KF+ EA I+K HP
Sbjct: 433 LVLGEQIGRGNFGEVFSG---RLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHP 489
Query: 485 HIVKLIGII-EEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESI 543
+IV+LIG+ +++P +I+MEL G+ +L L+V TL+ M YLES
Sbjct: 490 NIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESK 549
Query: 544 NCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKAS--VTRLPIKWMSPESINFRR 601
C+HRD+A RN LV +K+ DFG+SR E + Y AS + ++P+KW +PE++N+ R
Sbjct: 550 CCIHRDLAARNCLVTEKNVLKISDFGMSRE-EADGVYAASGGLRQVPVKWTAPEALNYGR 608
Query: 602 FTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRC 661
+++ SDVW F + +WE S G P+ L N+ +EKG RLP P+LCP ++ LM +C
Sbjct: 609 YSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFRLMEQC 668
Query: 662 WDYDPSDRPRFTELVCSLSDV 682
W Y+P RP F+ + L +
Sbjct: 669 WAYEPGQRPSFSTIYQELQSI 689
>gi|219842233 feline sarcoma oncogene isoform 3 [Homo sapiens]
Length = 752
Score = 204 bits (518), Expect = 4e-52
Identities = 115/321 (35%), Positives = 182/321 (56%), Gaps = 22/321 (6%)
Query: 367 RKDGEKRNSLPQIPML--NLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGIARED 424
R +GE P IP+L +L + + L++ + ++ +P + ++ + ED
Sbjct: 444 RLEGE---GFPSIPLLIDHLLSTQQPLTKKSGVV--LHRAVPKD--------KWVLNHED 490
Query: 425 VVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHP 484
+VL +G G FGEV+ G + + VAVK+C++ D K KF+ EA I+K HP
Sbjct: 491 LVLGEQIGRGNFGEVFSG---RLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHP 547
Query: 485 HIVKLIGII-EEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESI 543
+IV+LIG+ +++P +I+MEL G+ +L L+V TL+ M YLES
Sbjct: 548 NIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESK 607
Query: 544 NCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKAS--VTRLPIKWMSPESINFRR 601
C+HRD+A RN LV +K+ DFG+SR E + Y AS + ++P+KW +PE++N+ R
Sbjct: 608 CCIHRDLAARNCLVTEKNVLKISDFGMSRE-EADGVYAASGGLRQVPVKWTAPEALNYGR 666
Query: 602 FTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRC 661
+++ SDVW F + +WE S G P+ L N+ +EKG RLP P+LCP ++ LM +C
Sbjct: 667 YSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFRLMEQC 726
Query: 662 WDYDPSDRPRFTELVCSLSDV 682
W Y+P RP F+ + L +
Sbjct: 727 WAYEPGQRPSFSTIYQELQSI 747
>gi|219842230 feline sarcoma oncogene isoform 2 [Homo sapiens]
Length = 764
Score = 204 bits (518), Expect = 4e-52
Identities = 115/321 (35%), Positives = 182/321 (56%), Gaps = 22/321 (6%)
Query: 367 RKDGEKRNSLPQIPML--NLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGIARED 424
R +GE P IP+L +L + + L++ + ++ +P + ++ + ED
Sbjct: 456 RLEGE---GFPSIPLLIDHLLSTQQPLTKKSGVV--LHRAVPKD--------KWVLNHED 502
Query: 425 VVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHP 484
+VL +G G FGEV+ G + + VAVK+C++ D K KF+ EA I+K HP
Sbjct: 503 LVLGEQIGRGNFGEVFSG---RLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHP 559
Query: 485 HIVKLIGII-EEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESI 543
+IV+LIG+ +++P +I+MEL G+ +L L+V TL+ M YLES
Sbjct: 560 NIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESK 619
Query: 544 NCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKAS--VTRLPIKWMSPESINFRR 601
C+HRD+A RN LV +K+ DFG+SR E + Y AS + ++P+KW +PE++N+ R
Sbjct: 620 CCIHRDLAARNCLVTEKNVLKISDFGMSRE-EADGVYAASGGLRQVPVKWTAPEALNYGR 678
Query: 602 FTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRC 661
+++ SDVW F + +WE S G P+ L N+ +EKG RLP P+LCP ++ LM +C
Sbjct: 679 YSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFRLMEQC 738
Query: 662 WDYDPSDRPRFTELVCSLSDV 682
W Y+P RP F+ + L +
Sbjct: 739 WAYEPGQRPSFSTIYQELQSI 759
>gi|4503687 feline sarcoma oncogene isoform 1 [Homo sapiens]
Length = 822
Score = 204 bits (518), Expect = 4e-52
Identities = 115/321 (35%), Positives = 182/321 (56%), Gaps = 22/321 (6%)
Query: 367 RKDGEKRNSLPQIPML--NLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGIARED 424
R +GE P IP+L +L + + L++ + ++ +P + ++ + ED
Sbjct: 514 RLEGE---GFPSIPLLIDHLLSTQQPLTKKSGVV--LHRAVPKD--------KWVLNHED 560
Query: 425 VVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHP 484
+VL +G G FGEV+ G + + VAVK+C++ D K KF+ EA I+K HP
Sbjct: 561 LVLGEQIGRGNFGEVFSG---RLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHP 617
Query: 485 HIVKLIGII-EEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESI 543
+IV+LIG+ +++P +I+MEL G+ +L L+V TL+ M YLES
Sbjct: 618 NIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESK 677
Query: 544 NCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKAS--VTRLPIKWMSPESINFRR 601
C+HRD+A RN LV +K+ DFG+SR E + Y AS + ++P+KW +PE++N+ R
Sbjct: 678 CCIHRDLAARNCLVTEKNVLKISDFGMSRE-EADGVYAASGGLRQVPVKWTAPEALNYGR 736
Query: 602 FTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRC 661
+++ SDVW F + +WE S G P+ L N+ +EKG RLP P+LCP ++ LM +C
Sbjct: 737 YSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFRLMEQC 796
Query: 662 WDYDPSDRPRFTELVCSLSDV 682
W Y+P RP F+ + L +
Sbjct: 797 WAYEPGQRPSFSTIYQELQSI 817
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,802,862
Number of Sequences: 37866
Number of extensions: 2067261
Number of successful extensions: 10808
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 545
Number of HSP's successfully gapped in prelim test: 375
Number of HSP's that attempted gapping in prelim test: 8372
Number of HSP's gapped (non-prelim): 1663
length of query: 1009
length of database: 18,247,518
effective HSP length: 112
effective length of query: 897
effective length of database: 14,006,526
effective search space: 12563853822
effective search space used: 12563853822
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.