BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|27886568 interferon induced with helicase C domain 1 [Homo sapiens] (1025 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|27886568 interferon induced with helicase C domain 1 [Homo sa... 2050 0.0 gi|149408122 RNA helicase LGP2 [Homo sapiens] 510 e-144 gi|27881482 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide RIG-I [... 379 e-104 gi|29294649 dicer1 [Homo sapiens] 80 1e-14 gi|29294651 dicer1 [Homo sapiens] 80 1e-14 gi|74959747 Fanconi anemia, complementation group M [Homo sapiens] 70 8e-12 gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s... 50 1e-05 gi|4503529 eukaryotic translation initiation factor 4A isoform 1... 49 2e-05 gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 49 2e-05 gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] 45 4e-04 gi|13129006 nucleolar protein GU2 [Homo sapiens] 45 5e-04 gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi... 44 8e-04 gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi... 44 8e-04 gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ... 44 8e-04 gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [... 44 8e-04 gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ... 44 8e-04 gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 44 0.001 gi|40217847 activating signal cointegrator 1 complex subunit 3-l... 44 0.001 gi|169218225 PREDICTED: similar to U5 snRNP-specific 200kD prote... 43 0.001 gi|164419732 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 [Homo sap... 43 0.002 gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] 42 0.002 gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] 42 0.002 gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ... 42 0.003 gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [... 42 0.003 gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap... 41 0.007 gi|62241024 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 2 [... 40 0.009 gi|62241022 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 3 [... 40 0.009 gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1 [H... 40 0.009 gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] 40 0.009 gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] 40 0.009 >gi|27886568 interferon induced with helicase C domain 1 [Homo sapiens] Length = 1025 Score = 2050 bits (5311), Expect = 0.0 Identities = 1025/1025 (100%), Positives = 1025/1025 (100%) Query: 1 MSNGYSTDENFRYLISCFRARVKMYIQVEPVLDYLTFLPAEVKEQIQRTVATSGNMQAVE 60 MSNGYSTDENFRYLISCFRARVKMYIQVEPVLDYLTFLPAEVKEQIQRTVATSGNMQAVE Sbjct: 1 MSNGYSTDENFRYLISCFRARVKMYIQVEPVLDYLTFLPAEVKEQIQRTVATSGNMQAVE 60 Query: 61 LLLSTLEKGVWHLGWTREFVEALRRTGSPLAARYMNPELTDLPSPSFENAHDEYLQLLNL 120 LLLSTLEKGVWHLGWTREFVEALRRTGSPLAARYMNPELTDLPSPSFENAHDEYLQLLNL Sbjct: 61 LLLSTLEKGVWHLGWTREFVEALRRTGSPLAARYMNPELTDLPSPSFENAHDEYLQLLNL 120 Query: 121 LQPTLVDKLLVRDVLDKCMEEELLTIEDRNRIAAAENNGNESGVRELLKRIVQKENWFSA 180 LQPTLVDKLLVRDVLDKCMEEELLTIEDRNRIAAAENNGNESGVRELLKRIVQKENWFSA Sbjct: 121 LQPTLVDKLLVRDVLDKCMEEELLTIEDRNRIAAAENNGNESGVRELLKRIVQKENWFSA 180 Query: 181 FLNVLRQTGNNELVQELTGSDCSESNAEIENLSQVDGPQVEEQLLSTTVQPNLEKEVWGM 240 FLNVLRQTGNNELVQELTGSDCSESNAEIENLSQVDGPQVEEQLLSTTVQPNLEKEVWGM Sbjct: 181 FLNVLRQTGNNELVQELTGSDCSESNAEIENLSQVDGPQVEEQLLSTTVQPNLEKEVWGM 240 Query: 241 ENNSSESSFADSSVVSESDTSLAEGSVSCLDESLGHNSNMGSDSGTMGSDSDEENVAARA 300 ENNSSESSFADSSVVSESDTSLAEGSVSCLDESLGHNSNMGSDSGTMGSDSDEENVAARA Sbjct: 241 ENNSSESSFADSSVVSESDTSLAEGSVSCLDESLGHNSNMGSDSGTMGSDSDEENVAARA 300 Query: 301 SPEPELQLRPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHLDKKKKASEPGKVI 360 SPEPELQLRPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHLDKKKKASEPGKVI Sbjct: 301 SPEPELQLRPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHLDKKKKASEPGKVI 360 Query: 361 VLVNKVLLVEQLFRKEFQPFLKKWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENS 420 VLVNKVLLVEQLFRKEFQPFLKKWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENS Sbjct: 361 VLVNKVLLVEQLFRKEFQPFLKKWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENS 420 Query: 421 LLNLENGEDAGVQLSDFSLIIIDECHHTNKEAVYNNIMRHYLMQKLKNNRLKKENKPVIP 480 LLNLENGEDAGVQLSDFSLIIIDECHHTNKEAVYNNIMRHYLMQKLKNNRLKKENKPVIP Sbjct: 421 LLNLENGEDAGVQLSDFSLIIIDECHHTNKEAVYNNIMRHYLMQKLKNNRLKKENKPVIP 480 Query: 481 LPQILGLTASPGVGGATKQAKAEEHILKLCANLDAFTIKTVKENLDQLKNQIQEPCKKFA 540 LPQILGLTASPGVGGATKQAKAEEHILKLCANLDAFTIKTVKENLDQLKNQIQEPCKKFA Sbjct: 481 LPQILGLTASPGVGGATKQAKAEEHILKLCANLDAFTIKTVKENLDQLKNQIQEPCKKFA 540 Query: 541 IADATREDPFKEKLLEIMTRIQTYCQMSPMSDFGTQPYEQWAIQMEKKAAKEGNRKERVC 600 IADATREDPFKEKLLEIMTRIQTYCQMSPMSDFGTQPYEQWAIQMEKKAAKEGNRKERVC Sbjct: 541 IADATREDPFKEKLLEIMTRIQTYCQMSPMSDFGTQPYEQWAIQMEKKAAKEGNRKERVC 600 Query: 601 AEHLRKYNEALQINDTIRMIDAYTHLETFYNEEKDKKFAVIEDDSDEGGDDEYCDGDEDE 660 AEHLRKYNEALQINDTIRMIDAYTHLETFYNEEKDKKFAVIEDDSDEGGDDEYCDGDEDE Sbjct: 601 AEHLRKYNEALQINDTIRMIDAYTHLETFYNEEKDKKFAVIEDDSDEGGDDEYCDGDEDE 660 Query: 661 DDLKKPLKLDETDRFLMTLFFENNKMLKRLAENPEYENEKLTKLRNTIMEQYTRTEESAR 720 DDLKKPLKLDETDRFLMTLFFENNKMLKRLAENPEYENEKLTKLRNTIMEQYTRTEESAR Sbjct: 661 DDLKKPLKLDETDRFLMTLFFENNKMLKRLAENPEYENEKLTKLRNTIMEQYTRTEESAR 720 Query: 721 GIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIGAGHSSEFKPMTQNEQKEVISKFRT 780 GIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIGAGHSSEFKPMTQNEQKEVISKFRT Sbjct: 721 GIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIGAGHSSEFKPMTQNEQKEVISKFRT 780 Query: 781 GKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYVLVAHSGSGV 840 GKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYVLVAHSGSGV Sbjct: 781 GKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYVLVAHSGSGV 840 Query: 841 IEHETVNDFREKMMYKAIHCVQNMKPEEYAHKILELQMQSIMEKKMKTKRNIAKHYKNNP 900 IEHETVNDFREKMMYKAIHCVQNMKPEEYAHKILELQMQSIMEKKMKTKRNIAKHYKNNP Sbjct: 841 IEHETVNDFREKMMYKAIHCVQNMKPEEYAHKILELQMQSIMEKKMKTKRNIAKHYKNNP 900 Query: 901 SLITFLCKNCSVLACSGEDIHVIEKMHHVNMTPEFKELYIVRENKALQKKCADYQINGEI 960 SLITFLCKNCSVLACSGEDIHVIEKMHHVNMTPEFKELYIVRENKALQKKCADYQINGEI Sbjct: 901 SLITFLCKNCSVLACSGEDIHVIEKMHHVNMTPEFKELYIVRENKALQKKCADYQINGEI 960 Query: 961 ICKCGQAWGTMMVHKGLDLPCLKIRNFVVVFKNNSTKKQYKKWVELPITFPNLDYSECCL 1020 ICKCGQAWGTMMVHKGLDLPCLKIRNFVVVFKNNSTKKQYKKWVELPITFPNLDYSECCL Sbjct: 961 ICKCGQAWGTMMVHKGLDLPCLKIRNFVVVFKNNSTKKQYKKWVELPITFPNLDYSECCL 1020 Query: 1021 FSDED 1025 FSDED Sbjct: 1021 FSDED 1025 >gi|149408122 RNA helicase LGP2 [Homo sapiens] Length = 678 Score = 510 bits (1314), Expect = e-144 Identities = 293/717 (40%), Positives = 428/717 (59%), Gaps = 52/717 (7%) Query: 306 LQLRPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHLDKKKKASEPGKVIVLVNK 365 ++LR YQ EV PALEGKNIII LPTG+GKTR A Y+AK HL+ A KV+VLVN+ Sbjct: 1 MELRSYQWEVIMPALEGKNIIIWLPTGAGKTRAAAYVAKRHLETVDGA----KVVVLVNR 56 Query: 366 VLLVEQLFRKEFQPFLKKWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENSLLNLE 425 V LV Q +EF+ L + V LSGD + F + + D++I TA++L+ +L + E Sbjct: 57 VHLVTQ-HGEEFRRMLDGRWTVTTLSGDMGPRAGFGHLARCHDLLICTAELLQMALTSPE 115 Query: 426 NGEDAGVQLSDFSLIIIDECHHTNKEAVYNNIMRHYLMQKLKNNRLKKENKPVIPLPQIL 485 E+ V+L+ FSLI++DECHHT+K+ VYN IM YL KL+ + PLPQ+L Sbjct: 116 --EEEHVELTVFSLIVVDECHHTHKDTVYNVIMSQYLELKLQRAQ---------PLPQVL 164 Query: 486 GLTASPGVGGATKQAKAEEHILKLCANLDAFTIKTVKENLDQLKNQIQEPCKKFAIADAT 545 GLTASPG GGA+K A H+L+LCANLD + I + + QL+ Q+PCK++ + Sbjct: 165 GLTASPGTGGASKLDGAINHVLQLCANLDTWCIMSPQNCCPQLQEHSQQPCKQYNLCHRR 224 Query: 546 REDPFKEKLLEIMTRIQTYCQMSPMS-DFGTQPYEQWAIQMEKKAAKEGNRKERVCAEHL 604 +DPF + L ++M +I + +M +S FGTQ YEQ +++ + AA G +++RV A HL Sbjct: 225 SQDPFGDLLKKLMDQIHDHLEMPELSRKFGTQMYEQQVVKLSEAAALAGLQEQRVYALHL 284 Query: 605 RKYNEALQINDTIRMIDAYTHLETFYNEEKDKKFAVIEDDSDEGGDDEYCDGDEDEDDLK 664 R+YN+AL I+DT+R +DA L+ FY+ E K ++ C Sbjct: 285 RRYNDALLIHDTVRAVDALAALQDFYHREHVTKTQIL------------C---------- 322 Query: 665 KPLKLDETDRFLMTLFFENNKMLKRLAENPEYENEKLTKLRNTIMEQYTRTEESARGIIF 724 +R L+ LF + L LA + EN KL L + Q++ + S RGIIF Sbjct: 323 -------AERRLLALFDDRKNELAHLATHGP-ENPKLEMLEKILQRQFS-SSNSPRGIIF 373 Query: 725 TKTRQSAYALSQWITENEKFAEVGVKAHHLIGAGHSSEFKPMTQNEQKEVISKFRTGKIN 784 T+TRQSA++L W+ + + V ++A LIGAG+SS+ MTQ +Q+EVI KF+ G +N Sbjct: 374 TRTRQSAHSLLLWLQQQQGLQTVDIRAQLLIGAGNSSQSTHMTQRDQQEVIQKFQDGTLN 433 Query: 785 LLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYVLVAHSGSGVIEHE 844 LL+AT+VAEEGLDI CN+V+RYGL+TNEI+MVQARGRARAD+S Y VA GS ++ E Sbjct: 434 LLVATSVAEEGLDIPHCNVVVRYGLLTNEISMVQARGRARADQSVYAFVATEGSRELKRE 493 Query: 845 TVNDFREKMMYKAIHCVQNMKPEEYAHKILELQMQSIMEKKMKTKRNIAKHYKNNPSLIT 904 +N+ E +M +A+ VQ M EY KI +LQ ++ ++ + + + + + Sbjct: 494 LINEALETLMEQAVAAVQKMDQAEYQAKIRDLQQAALTKRAAQAAQRENQRQQFPVEHVQ 553 Query: 905 FLCKNCSVLACSGEDIHVIEKMHHVNMTPEFKELY-IVRENKALQKKCADYQINGEIICK 963 LC NC V G D+ +E HHVN+ P F Y + R+ + K D++ G I C+ Sbjct: 554 LLCINCMVAVGHGSDLRKVEGTHHVNVNPNFSNYYNVSRDPVVINKVFKDWKPGGVISCR 613 Query: 964 -CGQAWGTMMVHKGLDLPCLKIRNFVVVFKNNSTKKQYKKWVELPITFPNLDYSECC 1019 CG+ WG M++K + LP LK+R+ ++ + + Q KKW +P + P+ D+ + C Sbjct: 614 NCGEVWGLQMIYKSVKLPVLKVRS--MLLETPQGRIQAKKWSRVPFSVPDFDFLQHC 668 >gi|27881482 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide RIG-I [Homo sapiens] Length = 925 Score = 379 bits (972), Expect = e-104 Identities = 313/1022 (30%), Positives = 484/1022 (47%), Gaps = 149/1022 (14%) Query: 12 RYLISCFRARVKMYIQVEPVLDYLT-FLPAEVKEQIQRTVATSGNMQAVELLLSTLEKGV 70 R + F+ ++ + +L Y+ + E + IQ G M+A L L L + + Sbjct: 6 RRSLQAFQDYIRKTLDPTYILSYMAPWFREEEVQYIQAEKNNKGPMEAATLFLKFLLE-L 64 Query: 71 WHLGWTREFVEALRRTGSPLAARYMNPELTDLPSPSFENAHDEYLQLLNLLQPTLVDKLL 130 GW R F++AL G + Y E D +EY LL LQP +++ Sbjct: 65 QEEGWFRGFLDALDHAG--YSGLYEAIESWDFKKIE---KLEEYRLLLKRLQPEFKTRII 119 Query: 131 VRDVLDKCMEEELLTIEDRNRIAAAENNGNESGVRELLKRIVQ--KENWFSAFLNVLRQT 188 D++ + E L+ E + G +G +L++ +++ KENW L + Sbjct: 120 PTDIISD-LSECLINQECEEILQICSTKGMMAGAEKLVECLLRSDKENWPKTLKLALEKE 178 Query: 189 GNNELVQELTGSDCSESNAEIENLSQVDGPQVEEQLLSTTVQPNLEKEVWGMENNSSESS 248 N SE + + V+ +E+++ ++ +Q +++ N SE+S Sbjct: 179 RNK----------FSELWIVEKGIKDVETEDLEDKMETSDIQIFYQEDPECQ--NLSENS 226 Query: 249 FADSSVVSESDTSLAEGSVSCLDESLGHNSNMGSDSGTMGSDSDEENVAARASPEPELQL 308 S V SDT+L SP + Sbjct: 227 CPPSEV---SDTNLY-------------------------------------SP---FKP 243 Query: 309 RPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHLDKKKKASEPGKVIVLVNKVLL 368 R YQ+E+A PA++GKN IIC PTG GKT V++ I + HL KK + GKV+ N++ + Sbjct: 244 RNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHL-KKFPQGQKGKVVFFANQIPV 302 Query: 369 VEQ---LFRKEFQPFLKKWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENSLLNLE 425 EQ +F K F+ + YRV G+SG T + ++V++ DIII T QIL N NL+ Sbjct: 303 YEQQKSVFSKYFE---RHGYRVTGISGATAENVPVEQIVENNDIIILTPQILVN---NLK 356 Query: 426 NGEDAGVQLSDFSLIIIDECHHTNKEAVYNNIMRHYLMQKLKNNRLKKENKPVIPLPQIL 485 G LS F+L+I DECH+T+K+ YN IM +YL QKL + PLPQ++ Sbjct: 357 KGTIPS--LSIFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSG--------PLPQVI 406 Query: 486 GLTASPGVGGATKQAKAEEHILKLCANLDAFTIKTVKENLDQLKNQIQEPCKKFAIADAT 545 GLTAS GVG A +A ++I KLCA+LDA I TVK NL++L+ + +P K F ++ Sbjct: 407 GLTASVGVGDAKNTDEALDYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESR 466 Query: 546 REDPFKEKLLEIMTRIQTYCQ-----MSPMS-----DFGTQPYEQWAIQMEKKA----AK 591 D FK + ++M ++ + + +S +FGTQ YEQW + ++K Sbjct: 467 ISDKFKYIIAQLMRDTESLAKRICKDLENLSQIQNREFGTQKYEQWIVTVQKACMVFQMP 526 Query: 592 EGNRKERVC------AEHLRKYNEALQINDTIRMIDAYTHLETFYNEEKDKKFAVIEDDS 645 + + + R+C HLRKYN+AL I++ RM DA +L+ F++ + F IE D Sbjct: 527 DKDEESRICKALFLYTSHLRKYNDALIISEHARMKDALDYLKDFFSNVRAAGFDEIEQD- 585 Query: 646 DEGGDDEYCDGDEDEDDLKKPLKLDETDRFLMTLFFENNKMLKRLAENPEYENEKLTKLR 705 L F E + L+ ++ +P EN KL L Sbjct: 586 ------------------------------LTQRFEEKLQELESVSRDPSNENPKLEDLC 615 Query: 706 NTIMEQYTRTEESARGIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIGAGHSSEFKP 765 + E+Y E+ I+F KTR AL WI N K + +K L G G +++ Sbjct: 616 FILQEEYHLNPETIT-ILFVKTRALVDALKNWIEGNPKLS--FLKPGILTGRGKTNQNTG 672 Query: 766 MTQNEQKEVISKFR-TGKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRAR 824 MT QK ++ F+ +G N+LIAT+VA+EG+DI +CN+VI Y V N I M+Q RGR R Sbjct: 673 MTLPAQKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR 732 Query: 825 ADESTYVLVAHSGSGVIEHETVNDFREKMMYKAIHCVQNMKPEEYAHKILELQMQSIMEK 884 A S L+ S +GVIE E +N ++EKMM +I +Q + KIL +Q + Sbjct: 733 ARGSKCFLLT-SNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREKILHIQTHEKFIR 791 Query: 885 KMKTKRNIAKHYKNNPSLITFLCKNCSVLACSGEDIHVIEKMHHVNMTPEFKELYIVREN 944 + K +N LC+ C LAC D+ VIE+ H+ + FKE ++ R + Sbjct: 792 DSQEKPKPVPDKENK----KLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPH 847 Query: 945 KALQKKCADYQINGEIIC---KCGQAWGTMMVHKGLDLPCLKIRNFVVVFKNNSTKKQYK 1001 K+ + ++ +I C C WG + +K ++P +KI +FVV + Y Sbjct: 848 PK-PKQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQTLYS 906 Query: 1002 KW 1003 KW Sbjct: 907 KW 908 >gi|29294649 dicer1 [Homo sapiens] Length = 1922 Score = 79.7 bits (195), Expect = 1e-14 Identities = 52/153 (33%), Positives = 86/153 (56%), Gaps = 15/153 (9%) Query: 721 GIIFTKTRQSAYALSQWITE-NEKFAEVGVKAHHLIGAGHSSEFKPMTQN------EQKE 773 GIIF + R +A L++ I E ++ E+ + + I + +P + +Q+E Sbjct: 444 GIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGKNQPRNKQMEAEFRKQEE 503 Query: 774 VISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYVLV 833 V+ KFR + NLLIAT++ EEG+DI +CN+V+R+ L T + VQ++GRARA S Y+++ Sbjct: 504 VLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPISNYIML 563 Query: 834 AHSGSGVIEHETVNDFREKM-MYKAIHCVQNMK 865 A + + + F E + YKAI + K Sbjct: 564 A-------DTDKIKSFEEDLKTYKAIEKILRNK 589 Score = 56.6 bits (135), Expect = 1e-07 Identities = 63/209 (30%), Positives = 94/209 (44%), Gaps = 35/209 (16%) Query: 309 RPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKD-HLDKKKKASEPGK-VIVLVNKV 366 R YQ+E+ + AL+ N I+CL TGSGKT +AV + K+ + S GK + LVN Sbjct: 45 RKYQVELLEAALD-HNTIVCLNTGSGKTFIAVLLTKELSYQIRGDFSRNGKRTVFLVNSA 103 Query: 367 -LLVEQLFRKEFQPFLKKWYRVIGLSGDTQLKISFP-----EVVKSCDIIISTAQILENS 420 + +Q+ LK +G + ++ S+ + ++I T + N Sbjct: 104 NQVAQQVSAVRTHSDLK-----VGEYSNLEVNASWTKERWNQEFTKHQVLIMTCYVALNV 158 Query: 421 LLNLENGEDAGVQLSDFSLIIIDECHHTNKEAVYNNIMRHYLMQKLKNNRLKKENKPVIP 480 L N + LSD +L++ DECH + Y IM+ EN P Sbjct: 159 LKN------GYLSLSDINLLVFDECHLAILDHPYREIMK------------LCENCP--S 198 Query: 481 LPQILGLTASPGVGGATKQAKAEEHILKL 509 P+ILGLTAS + G + EE I KL Sbjct: 199 CPRILGLTASI-LNGKCDPEELEEKIQKL 226 >gi|29294651 dicer1 [Homo sapiens] Length = 1922 Score = 79.7 bits (195), Expect = 1e-14 Identities = 52/153 (33%), Positives = 86/153 (56%), Gaps = 15/153 (9%) Query: 721 GIIFTKTRQSAYALSQWITE-NEKFAEVGVKAHHLIGAGHSSEFKPMTQN------EQKE 773 GIIF + R +A L++ I E ++ E+ + + I + +P + +Q+E Sbjct: 444 GIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGKNQPRNKQMEAEFRKQEE 503 Query: 774 VISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYVLV 833 V+ KFR + NLLIAT++ EEG+DI +CN+V+R+ L T + VQ++GRARA S Y+++ Sbjct: 504 VLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPISNYIML 563 Query: 834 AHSGSGVIEHETVNDFREKM-MYKAIHCVQNMK 865 A + + + F E + YKAI + K Sbjct: 564 A-------DTDKIKSFEEDLKTYKAIEKILRNK 589 Score = 56.6 bits (135), Expect = 1e-07 Identities = 63/209 (30%), Positives = 94/209 (44%), Gaps = 35/209 (16%) Query: 309 RPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKD-HLDKKKKASEPGK-VIVLVNKV 366 R YQ+E+ + AL+ N I+CL TGSGKT +AV + K+ + S GK + LVN Sbjct: 45 RKYQVELLEAALD-HNTIVCLNTGSGKTFIAVLLTKELSYQIRGDFSRNGKRTVFLVNSA 103 Query: 367 -LLVEQLFRKEFQPFLKKWYRVIGLSGDTQLKISFP-----EVVKSCDIIISTAQILENS 420 + +Q+ LK +G + ++ S+ + ++I T + N Sbjct: 104 NQVAQQVSAVRTHSDLK-----VGEYSNLEVNASWTKERWNQEFTKHQVLIMTCYVALNV 158 Query: 421 LLNLENGEDAGVQLSDFSLIIIDECHHTNKEAVYNNIMRHYLMQKLKNNRLKKENKPVIP 480 L N + LSD +L++ DECH + Y IM+ EN P Sbjct: 159 LKN------GYLSLSDINLLVFDECHLAILDHPYREIMK------------LCENCP--S 198 Query: 481 LPQILGLTASPGVGGATKQAKAEEHILKL 509 P+ILGLTAS + G + EE I KL Sbjct: 199 CPRILGLTASI-LNGKCDPEELEEKIQKL 226 >gi|74959747 Fanconi anemia, complementation group M [Homo sapiens] Length = 2048 Score = 70.5 bits (171), Expect = 8e-12 Identities = 48/175 (27%), Positives = 84/175 (48%), Gaps = 19/175 (10%) Query: 696 YENEKLTKLRNTIMEQYT---------RTEESARGIIFTKTRQSAYALSQWITENEKFAE 746 Y + KL KL ++E + + + R +IF+ R S +++ +++++ Sbjct: 445 YSHPKLKKLEEVVIEHFKSWNAENTTEKKRDETRVMIFSSFRDSVQEIAEMLSQHQPI-- 502 Query: 747 VGVKAHHLIGAGHSSEFKPMTQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIR 806 ++ +G K TQ EQ EV+ +FR G N L++T V EEGLDI E +++I Sbjct: 503 --IRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDGGYNTLVSTCVGEEGLDIGEVDLIIC 560 Query: 807 YGLVTNEIAMVQARGR-ARADESTYVLVAHSGSGVIEHETVNDFR--EKMMYKAI 858 + + I +VQ GR R + V++ G E N + ++ +YKAI Sbjct: 561 FDSQKSPIRLVQRMGRTGRKRQGRIVIILSEGR---EERIYNQSQSNKRSIYKAI 612 Score = 44.3 bits (103), Expect = 6e-04 Identities = 45/185 (24%), Positives = 79/185 (42%), Gaps = 26/185 (14%) Query: 308 LRPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHLDKKKKASEPGKVIVLVNKVL 367 +R YQ+ +++ AL N ++CLPTG GKT +A + + + GKV+ + Sbjct: 91 VRDYQLHISRAALFC-NTLVCLPTGLGKTFIAAVVMYNFY----RWFPSGKVVFMAPTKP 145 Query: 368 LVEQLFRKEFQPFLKKWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENSLLNLENG 427 LV Q +Q + ++G TQ + E+ S ++ T Q++ N L Sbjct: 146 LVTQQIEACYQVMGIPQSHMAEMTGSTQAS-TRKEIWCSKRVLFLTPQVMVNDL------ 198 Query: 428 EDAGVQLSDFSLIIIDECHHTNKEAVYNNIMRHYLMQKLKNNRLKKENKPVIPLPQILGL 487 ++ ++IDE H Y ++R + K N+ +IL L Sbjct: 199 SRGACPAAEIKCLVIDEAHKALGNYAYCQVVRE--LVKYTNHF------------RILAL 244 Query: 488 TASPG 492 +A+PG Sbjct: 245 SATPG 249 >gi|83700235 eukaryotic translation initiation factor 4A2 [Homo sapiens] Length = 407 Score = 50.1 bits (118), Expect = 1e-05 Identities = 38/136 (27%), Positives = 62/136 (45%), Gaps = 19/136 (13%) Query: 687 LKRLAENPEYENEKLTKLRNTIMEQYTRTEESARGIIFTKTRQSAYALSQWITENEKFAE 746 +K+ N E E KL +T+ + Y T + +IF TR+ W+TE + Sbjct: 247 IKQFYINVEREEWKL----DTLCDLY-ETLTITQAVIFLNTRRKV----DWLTEKMHARD 297 Query: 747 VGVKAHHLIGAGHSSEFKPMTQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIR 806 V A H M Q E+ ++ +FR+G +LI T + G+D+++ ++VI Sbjct: 298 FTVSALH----------GDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVIN 347 Query: 807 YGLVTNEIAMVQARGR 822 Y L TN + GR Sbjct: 348 YDLPTNRENYIHRIGR 363 >gi|4503529 eukaryotic translation initiation factor 4A isoform 1 [Homo sapiens] Length = 406 Score = 49.3 bits (116), Expect = 2e-05 Identities = 37/130 (28%), Positives = 59/130 (45%), Gaps = 19/130 (14%) Query: 693 NPEYENEKLTKLRNTIMEQYTRTEESARGIIFTKTRQSAYALSQWITENEKFAEVGVKAH 752 N E E KL +T+ + Y T + +IF TR+ W+TE + V A Sbjct: 252 NVEREEWKL----DTLCDLY-ETLTITQAVIFINTRRKV----DWLTEKMHARDFTVSAM 302 Query: 753 HLIGAGHSSEFKPMTQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGLVTN 812 H M Q E+ ++ +FR+G +LI T + G+D+++ ++VI Y L TN Sbjct: 303 H----------GDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTN 352 Query: 813 EIAMVQARGR 822 + GR Sbjct: 353 RENYIHRIGR 362 >gi|7661920 eukaryotic translation initiation factor 4A, isoform 3 [Homo sapiens] Length = 411 Score = 48.9 bits (115), Expect = 2e-05 Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 22/145 (15%) Query: 679 LFFENNKMLKRLAENPEYENEKLTKLRNTIMEQYTRTEESARGIIFTKTRQSAYALSQWI 738 L E K E E++ + L L +T+ + +IF T++ W+ Sbjct: 246 LTLEGIKQFFVAVEREEWKFDTLCDLYDTLT--------ITQAVIFCNTKRKV----DWL 293 Query: 739 TENEKFAEVGVKAHHLIGAGHSSEFKPMTQNEQKEVISKFRTGKINLLIATTVAEEGLDI 798 TE + A V + H M Q E++ ++ +FR+G +LI+T V GLD+ Sbjct: 294 TEKMREANFTVSSMH----------GDMPQKERESIMKEFRSGASRVLISTDVWARGLDV 343 Query: 799 KECNIVIRYGLVTNEIAMVQARGRA 823 + +++I Y L N + GR+ Sbjct: 344 PQVSLIINYDLPNNRELYIHRIGRS 368 >gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] Length = 614 Score = 45.1 bits (105), Expect = 4e-04 Identities = 36/133 (27%), Positives = 61/133 (45%), Gaps = 19/133 (14%) Query: 697 ENEKLTKLRNTIMEQYTRTEESARGIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIG 756 ++EKL +L IM +E+ + I+F +T++ L++ K G A + G Sbjct: 325 KDEKLIRLMEEIM-----SEKENKTIVFVETKRRCDELTR------KMRRDGWPAMGIHG 373 Query: 757 AGHSSEFKPMTQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAM 816 +Q E+ V+++F+ GK +LIAT VA GLD+++ VI Y + Sbjct: 374 --------DKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDY 425 Query: 817 VQARGRARADEST 829 + GR T Sbjct: 426 IHRIGRTARSTKT 438 >gi|13129006 nucleolar protein GU2 [Homo sapiens] Length = 737 Score = 44.7 bits (104), Expect = 5e-04 Identities = 50/196 (25%), Positives = 83/196 (42%), Gaps = 15/196 (7%) Query: 252 SSVVSESDTSLAEGSVSCLDESLGHNSNMGSDSGTMGSDSDEENVAARASPEPELQLRPY 311 S VS DTS + S + L+E+L G+ S S+ + + R L P Sbjct: 108 SKRVSSLDTSTHKSSDNKLEETLTREQKEGAFSNFPISEETIKLLKGRGVT----YLFPI 163 Query: 312 QMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHLDKKK---KASEPGKVIVLVNKVLL 368 Q++ P EGK++I TG+GKT + L + + K S KV+VL L Sbjct: 164 QVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIERLQRNQETIKKSRSPKVLVLAPTREL 223 Query: 369 VEQLFRKEFQPFLKKWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENSLLNLENGE 428 Q+ K+F+ +K V G T + + DI++ T +++ L + Sbjct: 224 ANQV-AKDFKDITRK-LSVACFYGGTSYQSQINHIRNGIDILVGTPGRIKDHL------Q 275 Query: 429 DAGVQLSDFSLIIIDE 444 + LS +++DE Sbjct: 276 SGRLDLSKLRHVVLDE 291 Score = 38.9 bits (89), Expect = 0.025 Identities = 28/99 (28%), Positives = 50/99 (50%), Gaps = 17/99 (17%) Query: 708 IMEQYTRTEESARGIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIGAGHSSEFKPMT 767 +++ Y+ +E R IIF +T+++ +TE + A L G + Sbjct: 381 VLQVYSGSE--GRAIIFCETKKN-------VTEMAMNPHIKQNAQCLHG--------DIA 423 Query: 768 QNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIR 806 Q++++ + FR G +L+AT VA GLDI E ++VI+ Sbjct: 424 QSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQ 462 >gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapiens] Length = 491 Score = 43.9 bits (102), Expect = 8e-04 Identities = 20/56 (35%), Positives = 30/56 (53%) Query: 767 TQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGR 822 TQ ++ + FR GKI +LI T + G+D K N+VI Y T+ + + GR Sbjct: 339 TQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGR 394 Score = 38.1 bits (87), Expect = 0.043 Identities = 31/136 (22%), Positives = 61/136 (44%), Gaps = 7/136 (5%) Query: 310 PYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHLDKKKKASEPGKVIVLVNKVLLV 369 P QM+ L G+ ++ PTGSGKT + + K+ A++ + +++ L Sbjct: 82 PIQMQAIPVMLHGRELLASAPTGSGKT--LAFSIPILMQLKQPANKGFRALIISPTRELA 139 Query: 370 EQLFRKEFQPFLKKWYRVIGLSGDTQLKISF-PEVVKSCDIIISTAQILENSLLNLENGE 428 Q+ R+ + +R+ + F P+ K DI+++T N L+ L + Sbjct: 140 SQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTT----PNRLIYLLKQD 195 Query: 429 DAGVQLSDFSLIIIDE 444 G+ L+ +++DE Sbjct: 196 PPGIDLASVEWLVVDE 211 >gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapiens] Length = 599 Score = 43.9 bits (102), Expect = 8e-04 Identities = 20/56 (35%), Positives = 30/56 (53%) Query: 767 TQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGR 822 TQ ++ + FR GKI +LI T + G+D K N+VI Y T+ + + GR Sbjct: 447 TQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGR 502 Score = 38.1 bits (87), Expect = 0.043 Identities = 31/136 (22%), Positives = 61/136 (44%), Gaps = 7/136 (5%) Query: 310 PYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHLDKKKKASEPGKVIVLVNKVLLV 369 P QM+ L G+ ++ PTGSGKT + + K+ A++ + +++ L Sbjct: 190 PIQMQAIPVMLHGRELLASAPTGSGKT--LAFSIPILMQLKQPANKGFRALIISPTRELA 247 Query: 370 EQLFRKEFQPFLKKWYRVIGLSGDTQLKISF-PEVVKSCDIIISTAQILENSLLNLENGE 428 Q+ R+ + +R+ + F P+ K DI+++T N L+ L + Sbjct: 248 SQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTT----PNRLIYLLKQD 303 Query: 429 DAGVQLSDFSLIIIDE 444 G+ L+ +++DE Sbjct: 304 PPGIDLASVEWLVVDE 319 >gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 [Homo sapiens] Length = 724 Score = 43.9 bits (102), Expect = 8e-04 Identities = 37/145 (25%), Positives = 66/145 (45%), Gaps = 14/145 (9%) Query: 307 QLRPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHL-------DKKKKASEPGKV 359 +L P Q L G++++ C TGSGKT + H+ + K+ EP + Sbjct: 310 KLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECI 369 Query: 360 IVLVNKVLLVEQLFRKEFQPFLKKWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILEN 419 IV + LV Q++ + + R + + G TQL S ++V+ C+I+ +T Sbjct: 370 IVAPTRE-LVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCAT----PG 424 Query: 420 SLLNLENGEDAGVQLSDFSLIIIDE 444 L+++ E G L +++DE Sbjct: 425 RLMDIIGKEKIG--LKQIKYLVLDE 447 Score = 40.4 bits (93), Expect = 0.009 Identities = 31/126 (24%), Positives = 58/126 (46%), Gaps = 22/126 (17%) Query: 697 ENEKLTKLRNTIMEQYTRTEESARGIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIG 756 + EKL ++ I ++ T ++F +T++ A ++ ++ + EK + + Sbjct: 527 KREKLVEILRNIGDERT--------MVFVETKKKADFIATFLCQ-EKISTTSIHGDR--- 574 Query: 757 AGHSSEFKPMTQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAM 816 Q E+++ + FR GK +L+AT+VA GLDI+ VI + L + Sbjct: 575 ----------EQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEY 624 Query: 817 VQARGR 822 V GR Sbjct: 625 VHRIGR 630 >gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [Homo sapiens] Length = 724 Score = 43.9 bits (102), Expect = 8e-04 Identities = 37/145 (25%), Positives = 66/145 (45%), Gaps = 14/145 (9%) Query: 307 QLRPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHL-------DKKKKASEPGKV 359 +L P Q L G++++ C TGSGKT + H+ + K+ EP + Sbjct: 310 KLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECI 369 Query: 360 IVLVNKVLLVEQLFRKEFQPFLKKWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILEN 419 IV + LV Q++ + + R + + G TQL S ++V+ C+I+ +T Sbjct: 370 IVAPTRE-LVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCAT----PG 424 Query: 420 SLLNLENGEDAGVQLSDFSLIIIDE 444 L+++ E G L +++DE Sbjct: 425 RLMDIIGKEKIG--LKQIKYLVLDE 447 Score = 40.4 bits (93), Expect = 0.009 Identities = 31/126 (24%), Positives = 58/126 (46%), Gaps = 22/126 (17%) Query: 697 ENEKLTKLRNTIMEQYTRTEESARGIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIG 756 + EKL ++ I ++ T ++F +T++ A ++ ++ + EK + + Sbjct: 527 KREKLVEILRNIGDERT--------MVFVETKKKADFIATFLCQ-EKISTTSIHGDR--- 574 Query: 757 AGHSSEFKPMTQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAM 816 Q E+++ + FR GK +L+AT+VA GLDI+ VI + L + Sbjct: 575 ----------EQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEY 624 Query: 817 VQARGR 822 V GR Sbjct: 625 VHRIGR 630 >gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 [Homo sapiens] Length = 690 Score = 43.9 bits (102), Expect = 8e-04 Identities = 37/145 (25%), Positives = 66/145 (45%), Gaps = 14/145 (9%) Query: 307 QLRPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHL-------DKKKKASEPGKV 359 +L P Q L G++++ C TGSGKT + H+ + K+ EP + Sbjct: 276 KLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECI 335 Query: 360 IVLVNKVLLVEQLFRKEFQPFLKKWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILEN 419 IV + LV Q++ + + R + + G TQL S ++V+ C+I+ +T Sbjct: 336 IVAPTRE-LVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCAT----PG 390 Query: 420 SLLNLENGEDAGVQLSDFSLIIIDE 444 L+++ E G L +++DE Sbjct: 391 RLMDIIGKEKIG--LKQIKYLVLDE 413 Score = 40.4 bits (93), Expect = 0.009 Identities = 31/126 (24%), Positives = 58/126 (46%), Gaps = 22/126 (17%) Query: 697 ENEKLTKLRNTIMEQYTRTEESARGIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIG 756 + EKL ++ I ++ T ++F +T++ A ++ ++ + EK + + Sbjct: 493 KREKLVEILRNIGDERT--------MVFVETKKKADFIATFLCQ-EKISTTSIHGDR--- 540 Query: 757 AGHSSEFKPMTQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAM 816 Q E+++ + FR GK +L+AT+VA GLDI+ VI + L + Sbjct: 541 ----------EQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEY 590 Query: 817 VQARGR 822 V GR Sbjct: 591 VHRIGR 596 >gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo sapiens] Length = 662 Score = 43.5 bits (101), Expect = 0.001 Identities = 29/118 (24%), Positives = 56/118 (47%), Gaps = 14/118 (11%) Query: 705 RNTIMEQYTRTEESARGIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIGAGHSSEFK 764 R+ +++ T + + ++F +T++ A +L ++ G +S Sbjct: 428 RSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHE--------------GYACTSIHG 473 Query: 765 PMTQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGR 822 +Q +++E + +FR+GK +L+AT VA GLDI VI + L ++ V GR Sbjct: 474 DRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGR 531 >gi|40217847 activating signal cointegrator 1 complex subunit 3-like 1 [Homo sapiens] Length = 2136 Score = 43.5 bits (101), Expect = 0.001 Identities = 48/194 (24%), Positives = 88/194 (45%), Gaps = 15/194 (7%) Query: 298 ARASPEPELQLRPYQMEVAQPALE-GKNIIICLPTGSGKTRVAVYIAKDHLDKKKKAS-- 354 A+A E L Q ++ + ALE +N+++C PTG+GKT VA+ + K Sbjct: 471 AQAGFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGT 530 Query: 355 ---EPGKVIVLVNKVLLVEQLFRKEFQPFLKKWYRVIGLSGDTQLKISFPEVVKSCDIII 411 + K+I + LV+++ + V L+GD QL E + + II+ Sbjct: 531 INVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQL---CKEEISATQIIV 587 Query: 412 STAQILENSLLNLENGEDAGVQLSDFSLIIIDECHHTNKEAVYNNIMRHYLMQKLKNNRL 471 T + + ++ + GE QL LII+DE H + + ++ + + ++N + Sbjct: 588 CTPE--KWDIITRKGGERTYTQL--VRLIILDEIHLLHDDR--GPVLEALVARAIRNIEM 641 Query: 472 KKENKPVIPLPQIL 485 +E+ +I L L Sbjct: 642 TQEDVRLIGLSATL 655 Score = 35.0 bits (79), Expect = 0.36 Identities = 34/126 (26%), Positives = 64/126 (50%), Gaps = 16/126 (12%) Query: 324 NIIICLPTGSGKTRVAVYIAKDHLDKKKKASEPGKVIVLVNKVLLVEQLFR---KEFQPF 380 N+ + PTGSGKT A + + + S G+ + + L EQ++ ++FQ Sbjct: 1345 NVFVGAPTGSGKTICAEFA----ILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQDR 1400 Query: 381 LKKWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENSLLNLENGEDAGVQLSDFSLI 440 L K +V+ L+G+T + +++ +IIIST + + +L+ + VQ + +L Sbjct: 1401 LNK--KVVLLTGETSTDL---KLLGKGNIIISTPE--KWDILSRRWKQRKNVQ--NINLF 1451 Query: 441 IIDECH 446 ++DE H Sbjct: 1452 VVDEVH 1457 >gi|169218225 PREDICTED: similar to U5 snRNP-specific 200kD protein, partial [Homo sapiens] Length = 1700 Score = 43.1 bits (100), Expect = 0.001 Identities = 47/194 (24%), Positives = 88/194 (45%), Gaps = 15/194 (7%) Query: 298 ARASPEPELQLRPYQMEVAQPALE-GKNIIICLPTGSGKTRVAVYIAKDHLDKKKKAS-- 354 A+A E L Q ++ + ALE +N+++C PTG+GKT VA+ + K Sbjct: 35 AQAGFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGT 94 Query: 355 ---EPGKVIVLVNKVLLVEQLFRKEFQPFLKKWYRVIGLSGDTQLKISFPEVVKSCDIII 411 + K+I + LV+++ + V L+GD QL E + + II+ Sbjct: 95 INVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQL---CKEEISATQIIV 151 Query: 412 STAQILENSLLNLENGEDAGVQLSDFSLIIIDECHHTNKEAVYNNIMRHYLMQKLKNNRL 471 T + + ++ + GE QL LI++DE H + + ++ + + ++N + Sbjct: 152 CTPE--KWDIITRKGGERTYTQL--VRLIVLDEIHLLHDDR--GPVLEALVARAIRNIEM 205 Query: 472 KKENKPVIPLPQIL 485 +E+ +I L L Sbjct: 206 TQEDVRLIGLSATL 219 Score = 32.7 bits (73), Expect = 1.8 Identities = 34/126 (26%), Positives = 64/126 (50%), Gaps = 16/126 (12%) Query: 324 NIIICLPTGSGKTRVAVYIAKDHLDKKKKASEPGKVIVLVNKVLLVEQLFR---KEFQPF 380 N+ + PTGSGKT A + L + + G+ + + L EQ++ ++FQ Sbjct: 909 NVFVGAPTGSGKTICAEFAILRMLLQNSE----GRCVYITPMRLWQEQVYMDWYEKFQDR 964 Query: 381 LKKWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENSLLNLENGEDAGVQLSDFSLI 440 L K +V+ L+G+T + +++ +IIIST + + +L+ + VQ + +L Sbjct: 965 LNK--KVVLLTGETSTDL---KLLGKGNIIISTPE--KWDILSRRWKQRKNVQ--NINLF 1015 Query: 441 IIDECH 446 ++DE H Sbjct: 1016 VVDEVH 1021 >gi|164419732 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 [Homo sapiens] Length = 483 Score = 42.7 bits (99), Expect = 0.002 Identities = 27/92 (29%), Positives = 45/92 (48%), Gaps = 18/92 (19%) Query: 720 RGIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIGAGHSSEFKP--MTQNEQKEVISK 777 + IIF +TR++A +W+T +I GH +T ++ +I + Sbjct: 340 QAIIFCQTRRNA----KWLTVE------------MIQDGHQVSLLSGELTVEQRASIIQR 383 Query: 778 FRTGKINLLIATTVAEEGLDIKECNIVIRYGL 809 FR GK +LI T V G+D+K+ IV+ + L Sbjct: 384 FRDGKEKVLITTNVCARGIDVKQVTIVVNFDL 415 >gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] Length = 731 Score = 42.4 bits (98), Expect = 0.002 Identities = 22/56 (39%), Positives = 33/56 (58%) Query: 767 TQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGR 822 +Q E+ V+++FR+GK +LIAT VA GLD+++ VI Y + V GR Sbjct: 453 SQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGR 508 >gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] Length = 729 Score = 42.4 bits (98), Expect = 0.002 Identities = 22/56 (39%), Positives = 33/56 (58%) Query: 767 TQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGR 822 +Q E+ V+++FR+GK +LIAT VA GLD+++ VI Y + V GR Sbjct: 453 SQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGR 508 >gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [Homo sapiens] Length = 660 Score = 42.0 bits (97), Expect = 0.003 Identities = 29/118 (24%), Positives = 55/118 (46%), Gaps = 14/118 (11%) Query: 705 RNTIMEQYTRTEESARGIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIGAGHSSEFK 764 R+ +++ T + ++F +T++ A +L ++ G +S Sbjct: 426 RSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHE--------------GYACTSIHG 471 Query: 765 PMTQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGR 822 +Q +++E + +FR+GK +L+AT VA GLDI VI + L ++ V GR Sbjct: 472 DRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGR 529 >gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [Homo sapiens] Length = 660 Score = 42.0 bits (97), Expect = 0.003 Identities = 29/118 (24%), Positives = 55/118 (46%), Gaps = 14/118 (11%) Query: 705 RNTIMEQYTRTEESARGIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIGAGHSSEFK 764 R+ +++ T + ++F +T++ A +L ++ G +S Sbjct: 426 RSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHE--------------GYACTSIHG 471 Query: 765 PMTQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGR 822 +Q +++E + +FR+GK +L+AT VA GLDI VI + L ++ V GR Sbjct: 472 DRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGR 529 >gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sapiens] Length = 648 Score = 40.8 bits (94), Expect = 0.007 Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 12/133 (9%) Query: 768 QNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADE 827 Q ++++ + F+TGK+ +LIAT +A GLD+ + V + N V GR Sbjct: 523 QRDREKALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAG 582 Query: 828 STYVLVAHSGSGVIEHETVNDFR-EKMMYKAIHCVQNMKPEE---YAHKILELQMQSIME 883 T V + T ND+R + + PEE A + Q + ME Sbjct: 583 RTGVSITTL--------TRNDWRVASELINILERANQSIPEELVSMAERFKAHQQKREME 634 Query: 884 KKMKTKRNIAKHY 896 +KM+ + K + Sbjct: 635 RKMERPQGRPKKF 647 Score = 30.8 bits (68), Expect = 6.8 Identities = 34/139 (24%), Positives = 60/139 (43%), Gaps = 12/139 (8%) Query: 310 PYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHL----DKKKKASEPGKVIVLVNK 365 P Q + L+G ++I TG+GKT + HL K + + PG +++ + Sbjct: 267 PIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSLKGQRNRPGMLVLTPTR 326 Query: 366 VLLVEQLFRKEFQPFLKKWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENSLLNLE 425 L ++ E + K R + + G E+ K DIII+T L + L + Sbjct: 327 ELALQ--VEGECCKYSYKGLRSVCVYGGGNRDEQIEELKKGVDIIIATPGRLND--LQMS 382 Query: 426 NGEDAGVQLSDFSLIIIDE 444 N V L + + +++DE Sbjct: 383 N----FVNLKNITYLVLDE 397 >gi|62241024 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 2 [Homo sapiens] Length = 448 Score = 40.4 bits (93), Expect = 0.009 Identities = 28/91 (30%), Positives = 48/91 (52%), Gaps = 14/91 (15%) Query: 719 ARGIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIGAGHSSEFKPMTQNEQKEVISKF 778 A+ +IF TR++A W+ AE+ + H + A S E M ++ VI +F Sbjct: 303 AQAMIFCHTRKTA----SWLA-----AELSKEGHQV--ALLSGE---MMVEQRAAVIERF 348 Query: 779 RTGKINLLIATTVAEEGLDIKECNIVIRYGL 809 R GK +L+ T V G+D+++ ++VI + L Sbjct: 349 REGKEKVLVTTNVCARGIDVEQVSVVINFDL 379 >gi|62241022 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 3 [Homo sapiens] Length = 370 Score = 40.4 bits (93), Expect = 0.009 Identities = 28/91 (30%), Positives = 48/91 (52%), Gaps = 14/91 (15%) Query: 719 ARGIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIGAGHSSEFKPMTQNEQKEVISKF 778 A+ +IF TR++A W+ AE+ + H + A S E M ++ VI +F Sbjct: 225 AQAMIFCHTRKTA----SWLA-----AELSKEGHQV--ALLSGE---MMVEQRAAVIERF 270 Query: 779 RTGKINLLIATTVAEEGLDIKECNIVIRYGL 809 R GK +L+ T V G+D+++ ++VI + L Sbjct: 271 REGKEKVLVTTNVCARGIDVEQVSVVINFDL 301 >gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1 [Homo sapiens] Length = 479 Score = 40.4 bits (93), Expect = 0.009 Identities = 28/91 (30%), Positives = 48/91 (52%), Gaps = 14/91 (15%) Query: 719 ARGIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIGAGHSSEFKPMTQNEQKEVISKF 778 A+ +IF TR++A W+ AE+ + H + A S E M ++ VI +F Sbjct: 334 AQAMIFCHTRKTA----SWLA-----AELSKEGHQV--ALLSGE---MMVEQRAAVIERF 379 Query: 779 RTGKINLLIATTVAEEGLDIKECNIVIRYGL 809 R GK +L+ T V G+D+++ ++VI + L Sbjct: 380 REGKEKVLVTTNVCARGIDVEQVSVVINFDL 410 >gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] Length = 938 Score = 40.4 bits (93), Expect = 0.009 Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 7/89 (7%) Query: 753 HLIGAGHSSEFKPMTQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGL--- 809 H +G H M Q+E+ +VIS F+ I +L+AT VA GLDI VI Y + Sbjct: 523 HNLGLLHGD----MDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARD 578 Query: 810 VTNEIAMVQARGRARADESTYVLVAHSGS 838 + + GRA Y L+ S Sbjct: 579 IDTHTHRIGRTGRAGEKGVAYTLLTPKDS 607 Score = 32.3 bits (72), Expect = 2.3 Identities = 32/140 (22%), Positives = 60/140 (42%), Gaps = 8/140 (5%) Query: 307 QLRPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDH-LDKKKKASEPGKVIVLVNK 365 Q P Q + AL G+++I TGSGKT ++ H +D+K+ G + V+V Sbjct: 275 QPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCP 334 Query: 366 VLLVEQLFRKEFQPFLKKW-YRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENSLLNL 424 + Q E + F K + R + + G + + + +I++ T L + Sbjct: 335 TRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRL------I 388 Query: 425 ENGEDAGVQLSDFSLIIIDE 444 ++ + L S ++ DE Sbjct: 389 DHVKKKATNLQRVSYLVFDE 408 >gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] Length = 938 Score = 40.4 bits (93), Expect = 0.009 Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 7/89 (7%) Query: 753 HLIGAGHSSEFKPMTQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGL--- 809 H +G H M Q+E+ +VIS F+ I +L+AT VA GLDI VI Y + Sbjct: 523 HNLGLLHGD----MDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARD 578 Query: 810 VTNEIAMVQARGRARADESTYVLVAHSGS 838 + + GRA Y L+ S Sbjct: 579 IDTHTHRIGRTGRAGEKGVAYTLLTPKDS 607 Score = 32.3 bits (72), Expect = 2.3 Identities = 32/140 (22%), Positives = 60/140 (42%), Gaps = 8/140 (5%) Query: 307 QLRPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDH-LDKKKKASEPGKVIVLVNK 365 Q P Q + AL G+++I TGSGKT ++ H +D+K+ G + V+V Sbjct: 275 QPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCP 334 Query: 366 VLLVEQLFRKEFQPFLKKW-YRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENSLLNL 424 + Q E + F K + R + + G + + + +I++ T L + Sbjct: 335 TRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRL------I 388 Query: 425 ENGEDAGVQLSDFSLIIIDE 444 ++ + L S ++ DE Sbjct: 389 DHVKKKATNLQRVSYLVFDE 408 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.132 0.376 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 37,425,393 Number of Sequences: 37866 Number of extensions: 1701918 Number of successful extensions: 7974 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 66 Number of HSP's successfully gapped in prelim test: 93 Number of HSP's that attempted gapping in prelim test: 7141 Number of HSP's gapped (non-prelim): 773 length of query: 1025 length of database: 18,247,518 effective HSP length: 112 effective length of query: 913 effective length of database: 14,006,526 effective search space: 12787958238 effective search space used: 12787958238 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.