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Search of human proteins with 27886566
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27886566 mucosa associated lymphoid tissue lymphoma
translocation protein 1 isoform b [Homo sapiens]
(813 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27886566 mucosa associated lymphoid tissue lymphoma transloca... 1663 0.0
gi|5803078 mucosa associated lymphoid tissue lymphoma translocat... 1654 0.0
gi|157168355 CD22 molecule [Homo sapiens] 67 5e-11
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 65 2e-10
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 65 2e-10
gi|104487611 protein tyrosine phosphatase, receptor type, sigma ... 64 4e-10
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 63 1e-09
gi|118572606 hemicentin 1 [Homo sapiens] 61 4e-09
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ... 60 6e-09
gi|104487295 protein tyrosine phosphatase, receptor type, sigma ... 60 6e-09
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo... 60 1e-08
gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sa... 60 1e-08
gi|104487002 protein tyrosine phosphatase, receptor type, D isof... 59 1e-08
gi|7657359 contactin 5 isoform long [Homo sapiens] 59 1e-08
gi|28373129 contactin 5 isoform short [Homo sapiens] 59 1e-08
gi|205830473 sialic acid binding Ig-like lectin 11 isoform 2 [Ho... 59 1e-08
gi|205830470 sialic acid binding Ig-like lectin 11 isoform 1 [Ho... 59 1e-08
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ... 59 2e-08
gi|109150416 peroxidasin [Homo sapiens] 59 2e-08
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor... 58 3e-08
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 58 3e-08
gi|18860894 protein tyrosine phosphatase, receptor type, D isofo... 58 3e-08
gi|31377639 sialic acid binding Ig-like lectin 10 [Homo sapiens] 57 7e-08
gi|110349719 titin isoform N2-A [Homo sapiens] 56 1e-07
gi|40255157 leucine-rich repeats and immunoglobulin-like domains... 56 2e-07
gi|209862903 leucine-rich repeats and immunoglobulin-like domain... 56 2e-07
gi|19743806 roundabout 1 isoform b [Homo sapiens] 55 3e-07
gi|4506569 roundabout 1 isoform a [Homo sapiens] 55 3e-07
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 55 3e-07
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 55 3e-07
>gi|27886566 mucosa associated lymphoid tissue lymphoma
translocation protein 1 isoform b [Homo sapiens]
Length = 813
Score = 1663 bits (4306), Expect = 0.0
Identities = 813/813 (100%), Positives = 813/813 (100%)
Query: 1 MSLLGDPLQALPPSAAPTGPLLAPPAGATLNRLREPLLRRLSELLDQAPEGRGWRRLAEL 60
MSLLGDPLQALPPSAAPTGPLLAPPAGATLNRLREPLLRRLSELLDQAPEGRGWRRLAEL
Sbjct: 1 MSLLGDPLQALPPSAAPTGPLLAPPAGATLNRLREPLLRRLSELLDQAPEGRGWRRLAEL 60
Query: 61 AGSRGRLRLSCLDLEQCSLKVLEPEGSPSLCLLKLMGEKGCTVTELSDFLQAMEHTEVLQ 120
AGSRGRLRLSCLDLEQCSLKVLEPEGSPSLCLLKLMGEKGCTVTELSDFLQAMEHTEVLQ
Sbjct: 61 AGSRGRLRLSCLDLEQCSLKVLEPEGSPSLCLLKLMGEKGCTVTELSDFLQAMEHTEVLQ 120
Query: 121 LLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAV 180
LLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAV
Sbjct: 121 LLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAV 180
Query: 181 HVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMP 240
HVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMP
Sbjct: 181 HVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMP 240
Query: 241 GSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWCHVYNDRDSQD 300
GSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWCHVYNDRDSQD
Sbjct: 241 GSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWCHVYNDRDSQD 300
Query: 301 SKKVEIIIDELNNLGHPDNKEQTTDQPLAKDKVALLIGNMNYREHPKLKAPLVDVYELTN 360
SKKVEIIIDELNNLGHPDNKEQTTDQPLAKDKVALLIGNMNYREHPKLKAPLVDVYELTN
Sbjct: 301 SKKVEIIIDELNNLGHPDNKEQTTDQPLAKDKVALLIGNMNYREHPKLKAPLVDVYELTN 360
Query: 361 LLRQLDFKVVSLLDLTEYEMRNAVDEFLLLLDKGVYGLLYYAGHGYENFGNSFMVPVDAP 420
LLRQLDFKVVSLLDLTEYEMRNAVDEFLLLLDKGVYGLLYYAGHGYENFGNSFMVPVDAP
Sbjct: 361 LLRQLDFKVVSLLDLTEYEMRNAVDEFLLLLDKGVYGLLYYAGHGYENFGNSFMVPVDAP 420
Query: 421 NPYRSENCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDALKVTANIVFGYA 480
NPYRSENCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDALKVTANIVFGYA
Sbjct: 421 NPYRSENCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDALKVTANIVFGYA 480
Query: 481 TCQGAEAFEIQHSGLANGIFMKFLKDRLLEDKKITVLLDEVAEDMGKCHLTKGKQALEIR 540
TCQGAEAFEIQHSGLANGIFMKFLKDRLLEDKKITVLLDEVAEDMGKCHLTKGKQALEIR
Sbjct: 481 TCQGAEAFEIQHSGLANGIFMKFLKDRLLEDKKITVLLDEVAEDMGKCHLTKGKQALEIR 540
Query: 541 SSLSEKRALTDPIQGTEYSAESLVRNLQWAKAHELPESMCLKFDCGVQIQLGFAAEFSNV 600
SSLSEKRALTDPIQGTEYSAESLVRNLQWAKAHELPESMCLKFDCGVQIQLGFAAEFSNV
Sbjct: 541 SSLSEKRALTDPIQGTEYSAESLVRNLQWAKAHELPESMCLKFDCGVQIQLGFAAEFSNV 600
Query: 601 MIIYTSIVYKPPEIIMCDAYVTDFPLDLDIDPKDANKGTPEETGSYLVSKDLPKHCLYTR 660
MIIYTSIVYKPPEIIMCDAYVTDFPLDLDIDPKDANKGTPEETGSYLVSKDLPKHCLYTR
Sbjct: 601 MIIYTSIVYKPPEIIMCDAYVTDFPLDLDIDPKDANKGTPEETGSYLVSKDLPKHCLYTR 660
Query: 661 LSSLQKLKEHLVFTVCLSYQYSGLEDTVEDKQEVNVGKPLIAKLDMHRGLGRKTCFQTCL 720
LSSLQKLKEHLVFTVCLSYQYSGLEDTVEDKQEVNVGKPLIAKLDMHRGLGRKTCFQTCL
Sbjct: 661 LSSLQKLKEHLVFTVCLSYQYSGLEDTVEDKQEVNVGKPLIAKLDMHRGLGRKTCFQTCL 720
Query: 721 MSNGPYQSSAATSGGAGHYHSLQDPFHGVYHSHPGNPSNVTPADSCHCSRTPDAFISSFA 780
MSNGPYQSSAATSGGAGHYHSLQDPFHGVYHSHPGNPSNVTPADSCHCSRTPDAFISSFA
Sbjct: 721 MSNGPYQSSAATSGGAGHYHSLQDPFHGVYHSHPGNPSNVTPADSCHCSRTPDAFISSFA 780
Query: 781 HHASCHFSRSNVPVETTDEIPFSFSDRLRISEK 813
HHASCHFSRSNVPVETTDEIPFSFSDRLRISEK
Sbjct: 781 HHASCHFSRSNVPVETTDEIPFSFSDRLRISEK 813
>gi|5803078 mucosa associated lymphoid tissue lymphoma translocation
protein 1 isoform a [Homo sapiens]
Length = 824
Score = 1654 bits (4284), Expect = 0.0
Identities = 813/824 (98%), Positives = 813/824 (98%), Gaps = 11/824 (1%)
Query: 1 MSLLGDPLQALPPSAAPTGPLLAPPAGATLNRLREPLLRRLSELLDQAPEGRGWRRLAEL 60
MSLLGDPLQALPPSAAPTGPLLAPPAGATLNRLREPLLRRLSELLDQAPEGRGWRRLAEL
Sbjct: 1 MSLLGDPLQALPPSAAPTGPLLAPPAGATLNRLREPLLRRLSELLDQAPEGRGWRRLAEL 60
Query: 61 AGSRGRLRLSCLDLEQCSLKVLEPEGSPSLCLLKLMGEKGCTVTELSDFLQAMEHTEVLQ 120
AGSRGRLRLSCLDLEQCSLKVLEPEGSPSLCLLKLMGEKGCTVTELSDFLQAMEHTEVLQ
Sbjct: 61 AGSRGRLRLSCLDLEQCSLKVLEPEGSPSLCLLKLMGEKGCTVTELSDFLQAMEHTEVLQ 120
Query: 121 LLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAV 180
LLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAV
Sbjct: 121 LLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAV 180
Query: 181 HVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMP 240
HVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMP
Sbjct: 181 HVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMP 240
Query: 241 GSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWCHVYNDRDSQD 300
GSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWCHVYNDRDSQD
Sbjct: 241 GSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWCHVYNDRDSQD 300
Query: 301 SKKVEIII-----------DELNNLGHPDNKEQTTDQPLAKDKVALLIGNMNYREHPKLK 349
SKKVEIII DELNNLGHPDNKEQTTDQPLAKDKVALLIGNMNYREHPKLK
Sbjct: 301 SKKVEIIIGRTDEAVECTEDELNNLGHPDNKEQTTDQPLAKDKVALLIGNMNYREHPKLK 360
Query: 350 APLVDVYELTNLLRQLDFKVVSLLDLTEYEMRNAVDEFLLLLDKGVYGLLYYAGHGYENF 409
APLVDVYELTNLLRQLDFKVVSLLDLTEYEMRNAVDEFLLLLDKGVYGLLYYAGHGYENF
Sbjct: 361 APLVDVYELTNLLRQLDFKVVSLLDLTEYEMRNAVDEFLLLLDKGVYGLLYYAGHGYENF 420
Query: 410 GNSFMVPVDAPNPYRSENCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDAL 469
GNSFMVPVDAPNPYRSENCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDAL
Sbjct: 421 GNSFMVPVDAPNPYRSENCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDAL 480
Query: 470 KVTANIVFGYATCQGAEAFEIQHSGLANGIFMKFLKDRLLEDKKITVLLDEVAEDMGKCH 529
KVTANIVFGYATCQGAEAFEIQHSGLANGIFMKFLKDRLLEDKKITVLLDEVAEDMGKCH
Sbjct: 481 KVTANIVFGYATCQGAEAFEIQHSGLANGIFMKFLKDRLLEDKKITVLLDEVAEDMGKCH 540
Query: 530 LTKGKQALEIRSSLSEKRALTDPIQGTEYSAESLVRNLQWAKAHELPESMCLKFDCGVQI 589
LTKGKQALEIRSSLSEKRALTDPIQGTEYSAESLVRNLQWAKAHELPESMCLKFDCGVQI
Sbjct: 541 LTKGKQALEIRSSLSEKRALTDPIQGTEYSAESLVRNLQWAKAHELPESMCLKFDCGVQI 600
Query: 590 QLGFAAEFSNVMIIYTSIVYKPPEIIMCDAYVTDFPLDLDIDPKDANKGTPEETGSYLVS 649
QLGFAAEFSNVMIIYTSIVYKPPEIIMCDAYVTDFPLDLDIDPKDANKGTPEETGSYLVS
Sbjct: 601 QLGFAAEFSNVMIIYTSIVYKPPEIIMCDAYVTDFPLDLDIDPKDANKGTPEETGSYLVS 660
Query: 650 KDLPKHCLYTRLSSLQKLKEHLVFTVCLSYQYSGLEDTVEDKQEVNVGKPLIAKLDMHRG 709
KDLPKHCLYTRLSSLQKLKEHLVFTVCLSYQYSGLEDTVEDKQEVNVGKPLIAKLDMHRG
Sbjct: 661 KDLPKHCLYTRLSSLQKLKEHLVFTVCLSYQYSGLEDTVEDKQEVNVGKPLIAKLDMHRG 720
Query: 710 LGRKTCFQTCLMSNGPYQSSAATSGGAGHYHSLQDPFHGVYHSHPGNPSNVTPADSCHCS 769
LGRKTCFQTCLMSNGPYQSSAATSGGAGHYHSLQDPFHGVYHSHPGNPSNVTPADSCHCS
Sbjct: 721 LGRKTCFQTCLMSNGPYQSSAATSGGAGHYHSLQDPFHGVYHSHPGNPSNVTPADSCHCS 780
Query: 770 RTPDAFISSFAHHASCHFSRSNVPVETTDEIPFSFSDRLRISEK 813
RTPDAFISSFAHHASCHFSRSNVPVETTDEIPFSFSDRLRISEK
Sbjct: 781 RTPDAFISSFAHHASCHFSRSNVPVETTDEIPFSFSDRLRISEK 824
>gi|157168355 CD22 molecule [Homo sapiens]
Length = 847
Score = 67.4 bits (163), Expect = 5e-11
Identities = 51/176 (28%), Positives = 84/176 (47%), Gaps = 20/176 (11%)
Query: 123 SPPGIKITVNPESKAVLAGQFVKLCCR-ATGHPF-VQYQWFKMNKEIPNGNTSELIFNAV 180
+P +++ + +G V L C ++ HP VQ+ W K + + G S+L F+++
Sbjct: 504 APRDVRVRKIKPLSEIHSGNSVSLQCDFSSSHPKEVQFFWEKNGRLL--GKESQLNFDSI 561
Query: 181 HVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMP 240
+DAG Y C VNN+ S+ L+V P +L++ + P Q +M
Sbjct: 562 SPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPR------------RLRVSMSPGDQ-VME 608
Query: 241 GSTLVLQCVA-VGSPIPHYQWFK-NELPLTHETKKLYMVPYVDLEHQGTYWCHVYN 294
G + L C + P+ HY WF N L + ++KL + P V ++H G YWC N
Sbjct: 609 GKSATLTCESDANPPVSHYTWFDWNNQSLPYHSQKLRLEP-VKVQHSGAYWCQGTN 663
Score = 55.8 bits (133), Expect = 2e-07
Identities = 46/182 (25%), Positives = 73/182 (40%), Gaps = 17/182 (9%)
Query: 116 TEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGH--PFVQYQWFKMNKEIPNGNTS 173
T L + P ++I V P V G V + C + + W K + NT
Sbjct: 233 TVQLNVKHTPKLEIKVTPSDAIVREGDSVTMTCEVSSSNPEYTTVSWLKDGTSLKKQNTF 292
Query: 174 ELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEP 233
L V +G Y C+V+N+ S+ L V PE S +QI P
Sbjct: 293 TLNLREVTKDQSGKYCCQVSNDVGPGRSEEVFLQVQYAPEP----------STVQILHSP 342
Query: 234 TSQKLMPGSTLVLQCVAVGSPIP-HYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWCHV 292
+ GS + C+++ +P+P +Y W+ N + T++ +P + H GTY C
Sbjct: 343 AVE----GSQVEFLCMSLANPLPTNYTWYHNGKEMQGRTEEKVHIPKILPWHAGTYSCVA 398
Query: 293 YN 294
N
Sbjct: 399 EN 400
Score = 40.0 bits (92), Expect = 0.009
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 2/100 (2%)
Query: 121 LLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQ-YQWFKMNKEIPNGNTSELIFNA 179
L +P ++++++P + V+ G+ L C + +P V Y WF N + ++ +L
Sbjct: 590 LYAPRRLRVSMSPGDQ-VMEGKSATLTCESDANPPVSHYTWFDWNNQSLPYHSQKLRLEP 648
Query: 180 VHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSV 219
V V+ +G Y C+ N+ S S L V PE+ R V
Sbjct: 649 VKVQHSGAYWCQGTNSVGKGRSPLSTLTVYYSPETIGRRV 688
Score = 31.6 bits (70), Expect = 3.1
Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 4/82 (4%)
Query: 226 KLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHY---QWFKNELPLTHETKKLYMVPYVDL 282
KL+I V P+ + G ++ + C V S P Y W K+ L + + V
Sbjct: 243 KLEIKVTPSDAIVREGDSVTMTC-EVSSSNPEYTTVSWLKDGTSLKKQNTFTLNLREVTK 301
Query: 283 EHQGTYWCHVYNDRDSQDSKKV 304
+ G Y C V ND S++V
Sbjct: 302 DQSGKYCCQVSNDVGPGRSEEV 323
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform
1 precursor [Homo sapiens]
Length = 1907
Score = 65.5 bits (158), Expect = 2e-10
Identities = 50/181 (27%), Positives = 78/181 (43%), Gaps = 23/181 (12%)
Query: 101 CTVTELSDFLQAMEHTEVLQLLS-PPGI-KITVNPESKAVLAGQFVKLCCRATGHPFVQY 158
CT T + VL+ PPG I + P+ K V + + C A G+P +
Sbjct: 107 CTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEI 166
Query: 159 QWFK----MNKEIPNGNTSELIFNAVHVK-----DAGFYVCRVNNNFTFEFSQWSQLDVC 209
WFK ++ NG +L A+ ++ D G Y C N+ +S + L V
Sbjct: 167 SWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYV- 225
Query: 210 DIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTH 269
V + + P+SQ++MPG ++ L CVAVG+P+P+ +W LT
Sbjct: 226 -----------RVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTK 274
Query: 270 E 270
E
Sbjct: 275 E 275
Score = 48.1 bits (113), Expect = 3e-05
Identities = 47/199 (23%), Positives = 74/199 (37%), Gaps = 35/199 (17%)
Query: 133 PESKAVLAGQFVKLCCRATGHPFVQYQWFKMNK----------EIPNGNTSELIFNAVHV 182
PE + L+G C+ATG P + W K K E +G S L + V
Sbjct: 39 PEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRV 98
Query: 183 -KDAGFYVCRVNNNFTFEFSQWSQLDVCD---IPESFQRSVDGVSESKLQICVEPTSQKL 238
+D Y C N+ E + ++L V + +P F S+D + P + +
Sbjct: 99 QRDEAIYECTATNSLG-EINTSAKLSVLEEEQLPPGFP-SID----------MGPQLKVV 146
Query: 239 MPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKK---------LYMVPYVDLEHQGTYW 289
T + C A G+P P WFK+ LP+ T + + QG Y
Sbjct: 147 EKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYE 206
Query: 290 CHVYNDRDSQDSKKVEIII 308
C N ++ S + +
Sbjct: 207 CVATNSAGTRYSAPANLYV 225
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform
2 precursor [Homo sapiens]
Length = 1898
Score = 65.5 bits (158), Expect = 2e-10
Identities = 50/181 (27%), Positives = 78/181 (43%), Gaps = 23/181 (12%)
Query: 101 CTVTELSDFLQAMEHTEVLQLLS-PPGI-KITVNPESKAVLAGQFVKLCCRATGHPFVQY 158
CT T + VL+ PPG I + P+ K V + + C A G+P +
Sbjct: 107 CTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEI 166
Query: 159 QWFK----MNKEIPNGNTSELIFNAVHVK-----DAGFYVCRVNNNFTFEFSQWSQLDVC 209
WFK ++ NG +L A+ ++ D G Y C N+ +S + L V
Sbjct: 167 SWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYV- 225
Query: 210 DIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTH 269
V + + P+SQ++MPG ++ L CVAVG+P+P+ +W LT
Sbjct: 226 -----------RVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTK 274
Query: 270 E 270
E
Sbjct: 275 E 275
Score = 48.1 bits (113), Expect = 3e-05
Identities = 47/199 (23%), Positives = 74/199 (37%), Gaps = 35/199 (17%)
Query: 133 PESKAVLAGQFVKLCCRATGHPFVQYQWFKMNK----------EIPNGNTSELIFNAVHV 182
PE + L+G C+ATG P + W K K E +G S L + V
Sbjct: 39 PEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRV 98
Query: 183 -KDAGFYVCRVNNNFTFEFSQWSQLDVCD---IPESFQRSVDGVSESKLQICVEPTSQKL 238
+D Y C N+ E + ++L V + +P F S+D + P + +
Sbjct: 99 QRDEAIYECTATNSLG-EINTSAKLSVLEEEQLPPGFP-SID----------MGPQLKVV 146
Query: 239 MPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKK---------LYMVPYVDLEHQGTYW 289
T + C A G+P P WFK+ LP+ T + + QG Y
Sbjct: 147 EKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYE 206
Query: 290 CHVYNDRDSQDSKKVEIII 308
C N ++ S + +
Sbjct: 207 CVATNSAGTRYSAPANLYV 225
>gi|104487611 protein tyrosine phosphatase, receptor type, sigma
isoform 4 precursor [Homo sapiens]
Length = 1505
Score = 64.3 bits (155), Expect = 4e-10
Identities = 42/151 (27%), Positives = 70/151 (46%), Gaps = 17/151 (11%)
Query: 129 ITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFK----MNKEIPNGNTSELIFNAVHVK- 183
I + P+ K V + + C A+G+P + WFK ++ NG +L A+ ++
Sbjct: 137 IDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIES 196
Query: 184 ----DAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLM 239
D G Y C N+ +S + L V ++ E V + + P S ++M
Sbjct: 197 SEETDQGKYECVATNSAGVRYSSPANLYVRELRE--------VRRVAPRFSILPMSHEIM 248
Query: 240 PGSTLVLQCVAVGSPIPHYQWFKNELPLTHE 270
PG + + CVAVGSP+P+ +W + LT E
Sbjct: 249 PGGNVNITCVAVGSPMPYVKWMQGAEDLTPE 279
Score = 38.9 bits (89), Expect = 0.019
Identities = 45/205 (21%), Positives = 75/205 (36%), Gaps = 35/205 (17%)
Query: 133 PESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAV-----------H 181
P+ + ++G C+ATG P + W K K++ + + F+
Sbjct: 39 PKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRT 98
Query: 182 VKDAGFYVCRVNNNFTFEFSQWSQLDVC---DIPESFQRSVDGVSESKLQICVEPTSQKL 238
+D Y C V N E + ++L V +P F ++D + K+ VE T
Sbjct: 99 PRDENVYEC-VAQNSVGEITVHAKLTVLREDQLPSGFP-NIDMGPQLKV---VERT---- 149
Query: 239 MPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKK---------LYMVPYVDLEHQGTYW 289
T + C A G+P P WFK+ LP+ + + QG Y
Sbjct: 150 ---RTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYE 206
Query: 290 CHVYNDRDSQDSKKVEIIIDELNNL 314
C N + S + + EL +
Sbjct: 207 CVATNSAGVRYSSPANLYVRELREV 231
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 62.8 bits (151), Expect = 1e-09
Identities = 51/177 (28%), Positives = 75/177 (42%), Gaps = 15/177 (8%)
Query: 122 LSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNT---SELIFN 178
+SPP I + S V+ GQ + L C P W+K +P+ + S L +
Sbjct: 2628 VSPP---IRIESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQTHGSHLRLH 2684
Query: 179 AVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKL 238
+ V D+G YVCR NNN + + + + P + S G S + I +E +S +
Sbjct: 2685 QMSVADSGEYVCRANNNID---ALEASIVISVSPSAGSPSAPG---SSMPIRIESSSSHV 2738
Query: 239 MPGSTLVLQCVAVGSPIPHYQWFK--NELPLTHETK-KLYMVPYVDLEHQGTYWCHV 292
G TL L CV G W K LP H+T+ + +V G Y C V
Sbjct: 2739 AEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRV 2795
Score = 62.4 bits (150), Expect = 2e-09
Identities = 60/201 (29%), Positives = 79/201 (39%), Gaps = 14/201 (6%)
Query: 101 CTVTELSDFLQAMEHTEVLQL--LSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQY 158
C T + QA VL SPP +KI S +V GQ + L C G Q
Sbjct: 2025 CVATSPAGTAQARIQVVVLSASDASPPPVKI--ESSSPSVTEGQTLDLNCVVAGSAHAQV 2082
Query: 159 QWFKMNKEIP---NGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESF 215
W++ +P + S L V D+G YVCRV N + + + V + +
Sbjct: 2083 TWYRRGGSLPPHTQVHGSRLRLPQVSPADSGEYVCRVENG---SGPKEASITVSVLHGTH 2139
Query: 216 QR-SVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFK--NELPLTHETK 272
S V S I +EP+S + G TL L CV G W K LP H+T
Sbjct: 2140 SGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARHQTH 2199
Query: 273 -KLYMVPYVDLEHQGTYWCHV 292
L + V G Y CHV
Sbjct: 2200 GSLLRLHQVTPADSGEYVCHV 2220
Score = 62.0 bits (149), Expect = 2e-09
Identities = 52/186 (27%), Positives = 76/186 (40%), Gaps = 20/186 (10%)
Query: 118 VLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSE--- 174
VL + G ++ V+PE V AG+ V+L CRA G P W K +P SE
Sbjct: 1947 VLHVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERTD 2006
Query: 175 ---LIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICV 231
L+ A+ DAGFY+C + + +++ V + S S + +
Sbjct: 2007 IATLLIPAITTADAGFYLCVATSP---AGTAQARIQVVVLSAS--------DASPPPVKI 2055
Query: 232 EPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETK---KLYMVPYVDLEHQGTY 288
E +S + G TL L CV GS W++ L T+ +P V G Y
Sbjct: 2056 ESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGSRLRLPQVSPADSGEY 2115
Query: 289 WCHVYN 294
C V N
Sbjct: 2116 VCRVEN 2121
Score = 62.0 bits (149), Expect = 2e-09
Identities = 55/187 (29%), Positives = 83/187 (44%), Gaps = 12/187 (6%)
Query: 114 EHTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTS 173
E T +L + SPP T PE +V AG+ V+L C A G P + +QW ++ +P T+
Sbjct: 3288 EATIILHVESPP--YATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATA 3345
Query: 174 E---LIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESF-QRSVDGVSESKLQI 229
L F +D+G Y CRV N ++QL V P S S+ S +Q
Sbjct: 3346 RNELLHFERAAPEDSGRYRCRVTNK-VGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQ- 3403
Query: 230 CVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFK--NELPLTHETKK-LYMVPYVDLEHQG 286
V P + G+++ C +WFK +LP H + + + +D QG
Sbjct: 3404 -VTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQG 3462
Query: 287 TYWCHVY 293
TY C +
Sbjct: 3463 TYICQAH 3469
Score = 58.9 bits (141), Expect = 2e-08
Identities = 55/206 (26%), Positives = 78/206 (37%), Gaps = 20/206 (9%)
Query: 97 GEKGCTVTELSDFLQAMEHTEVLQLLSPPGIK-ITVNPESKAVLAGQFVKLCCRATGHPF 155
GE C V S L+A + + P I + + S V GQ + L C G
Sbjct: 2214 GEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAH 2273
Query: 156 VQYQWFKMNKEIPNGNT---SELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIP 212
Q W+K +P + S L DAG YVCR +N + +
Sbjct: 2274 AQVTWYKRGGSLPARHQVRGSRLYIFQASPADAGQYVCRASNGMEASIT-------VTVT 2326
Query: 213 ESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFK--NELPLTHE 270
+ ++ + S I +EP+S ++ G TL L CV G W K LP+ H+
Sbjct: 2327 GTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRGGSLPVRHQ 2386
Query: 271 TK----KLYMVPYVDLEHQGTYWCHV 292
T +LY D G Y C V
Sbjct: 2387 THGSLLRLYQASPAD---SGEYVCRV 2409
Score = 58.2 bits (139), Expect = 3e-08
Identities = 61/224 (27%), Positives = 87/224 (38%), Gaps = 22/224 (9%)
Query: 97 GEKGCTVTELSDFLQAMEHTEVLQLLSPPGIKIT----VNPESKAVLAGQFVKLCCRATG 152
GE C V S L+A + S P + +T + S V GQ + L C G
Sbjct: 2403 GEYVCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAG 2462
Query: 153 HPFVQYQWFKMNKEIPNGNT---SELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVC 209
Q W K +P + S L V D+G YVCRV + S
Sbjct: 2463 QAHAQVTWHKRGGSLPARHQVHGSRLRLLQVTPADSGEYVCRVVGS--------SGTQEA 2514
Query: 210 DIPESFQRSVDGVSESKLQ--ICVEPTSQKLMPGSTLVLQCVAVGSPIPH-YQWFKN--E 264
+ + Q+ + G + + +E +S L G TL L C+ V S PH W+K
Sbjct: 2515 SVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCL-VASQAPHTITWYKRGGS 2573
Query: 265 LPLTHE-TKKLYMVPYVDLEHQGTYWCHVYNDRDSQDSKKVEII 307
LP H+ +P V G Y CHV N S+++ + I
Sbjct: 2574 LPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTI 2617
Score = 53.1 bits (126), Expect = 1e-06
Identities = 50/190 (26%), Positives = 73/190 (38%), Gaps = 39/190 (20%)
Query: 118 VLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEI-PNGNTSELI 176
V+Q L P + I + + V+ G V+ C A G P Q W K+ + P S +
Sbjct: 3482 VIQAL--PSVLINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHLRPGIVQSGGV 3539
Query: 177 FNAVHVK--DAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPT 234
HV+ DAG Y C N G ++S + + V+
Sbjct: 3540 VRIAHVELADAGQYRCTATN------------------------AAGTTQSHVLLLVQAL 3575
Query: 235 SQKLMP-------GSTLVLQCVAVGSPIPHYQWFKNELPLTHETK---KLYMVPYVDLEH 284
Q MP GS V C+A G P P W K + L +++ + M+P V +
Sbjct: 3576 PQISMPQEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPPDSRLENNMLMLPSVRPQD 3635
Query: 285 QGTYWCHVYN 294
GTY C N
Sbjct: 3636 AGTYVCTATN 3645
Score = 52.0 bits (123), Expect = 2e-06
Identities = 54/212 (25%), Positives = 85/212 (40%), Gaps = 19/212 (8%)
Query: 96 MGEKGCTVTELSDFLQAMEHTEVLQLL------SPPGIKITVNPESKA--VLAGQFVKLC 147
+ + G V ++ + A+E + V+ + S PG + + ES + V G+ + L
Sbjct: 2688 VADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLN 2747
Query: 148 CRATGHPFVQYQWFKMNKEIPNGNT---SELIFNAVHVKDAGFYVCRV-NNNFTFEFSQW 203
C G Q W K +P+ + S L + V D+G YVCRV ++ E S
Sbjct: 2748 CVVPGQAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVL 2807
Query: 204 SQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFK- 262
++ + G I +EP+S ++ G TL L+CV G W K
Sbjct: 2808 VTIEASGSSAVHVPAPGGAPP----IRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKR 2863
Query: 263 -NELPLTHETK-KLYMVPYVDLEHQGTYWCHV 292
LP H+ L + V G Y C V
Sbjct: 2864 GGNLPARHQVHGPLLRLNQVSPADSGEYSCQV 2895
Score = 49.3 bits (116), Expect = 1e-05
Identities = 51/181 (28%), Positives = 72/181 (39%), Gaps = 28/181 (15%)
Query: 123 SPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSE---LIFNA 179
+PP I + P S V GQ + L C G Q W K +P + L N
Sbjct: 2826 APP---IRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQ 2882
Query: 180 VHVKDAGFYVCRVNNNF-TFEFSQWSQLDVCD---IPESFQRSVDGVSESKLQICVEPTS 235
V D+G Y C+V + T E S ++ IP G+++ I +E +S
Sbjct: 2883 VSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIP------APGLAQP---IYIEASS 2933
Query: 236 QKLMPGSTLVLQCVAVGSPIPHYQWFK--NELPLTHETK----KLYMVPYVDLEHQGTYW 289
+ G TL L CV G W+K LP H+T +L++V D G Y
Sbjct: 2934 SHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRLHLVSPAD---SGEYV 2990
Query: 290 C 290
C
Sbjct: 2991 C 2991
Score = 48.1 bits (113), Expect = 3e-05
Identities = 49/194 (25%), Positives = 74/194 (38%), Gaps = 21/194 (10%)
Query: 129 ITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIP---NGNTSELIFNAVHVKDA 185
I + P S V GQ + L C G Q W K +P + S L D+
Sbjct: 2343 IRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRGGSLPVRHQTHGSLLRLYQASPADS 2402
Query: 186 GFYVCRV-NNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTL 244
G YVCRV ++ E S ++ + GV+ + + +E +S ++ G TL
Sbjct: 2403 GEYVCRVLGSSVPLEASVLVTIEPAGSVPAL-----GVTPT---VRIESSSSQVAEGQTL 2454
Query: 245 VLQCVAVGSPIPHYQWFK--NELPLTHETK----KLYMVPYVDLEHQGTYWCHVYNDRDS 298
L C+ G W K LP H+ +L V D G Y C V +
Sbjct: 2455 DLNCLVAGQAHAQVTWHKRGGSLPARHQVHGSRLRLLQVTPAD---SGEYVCRVVGSSGT 2511
Query: 299 QDSKKVEIIIDELN 312
Q++ + I L+
Sbjct: 2512 QEASVLVTIQQRLS 2525
Score = 43.9 bits (102), Expect = 6e-04
Identities = 45/186 (24%), Positives = 72/186 (38%), Gaps = 25/186 (13%)
Query: 119 LQLLSPPGIKITVNPESKA-VLAGQFVKLCCRATGHPFVQYQWFKMNKEIPN-------- 169
L + PP ++V PE V G+ V L C + G P +W +++
Sbjct: 3106 LSVHGPP--TVSVLPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGL 3163
Query: 170 -GNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQ 228
+ + L ++ DAG YVC N + Q++V + V + +
Sbjct: 3164 MDSHAVLQISSAKPSDAGTYVCLAQNALG---TAQKQVEVIVDTGAMAPGAPQVQAEEAE 3220
Query: 229 ICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETK---KLYMVPYVDLEHQ 285
+ VE G T L+C A GSP P W K PL + + ++P V +
Sbjct: 3221 LTVEA-------GHTATLRCSATGSPAPTIHWSKLRSPLPWQHRLEGDTLIIPRVAQQDS 3273
Query: 286 GTYWCH 291
G Y C+
Sbjct: 3274 GQYICN 3279
Score = 43.5 bits (101), Expect = 8e-04
Identities = 51/217 (23%), Positives = 82/217 (37%), Gaps = 28/217 (12%)
Query: 101 CTVTELSDFLQAMEHTEVLQLLSPPGIKITVNPE-SKAVLAGQFVKLCCRATGH-PFVQY 158
CT L + V + S P I +TV + S++V G V C A P
Sbjct: 1746 CTCRNLHQSNTSRAELLVTEAPSKP-ITVTVEEQRSQSVRPGADVTFICTAKSKSPAYTL 1804
Query: 159 QWFKM-NKEIPNGNTSELIFNA------VHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDI 211
W ++ N ++P T + FN V + DAG YVC +N F +
Sbjct: 1805 VWTRLHNGKLP---TRAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGT--------- 1852
Query: 212 PESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWF---KNELPLT 268
+ G + + + + P + PG +C A GSP P +W +LP
Sbjct: 1853 -ATLHVQASGTLSAPV-VSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGGPGGQLPAK 1910
Query: 269 HETK-KLYMVPYVDLEHQGTYWCHVYNDRDSQDSKKV 304
+ + +P V+ Q Y C ++ Q ++ V
Sbjct: 1911 AQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAV 1947
Score = 42.4 bits (98), Expect = 0.002
Identities = 45/173 (26%), Positives = 70/173 (40%), Gaps = 22/173 (12%)
Query: 129 ITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMN-KEIPNGNT-----SELIFNAVHV 182
+ V+P V G L C+ +G P + W + + + +P+G SEL F +V
Sbjct: 1679 VEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSELHFPSVQP 1738
Query: 183 KDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGS 242
DAG Y+C N S+ ++L V + P S+ E SQ + PG+
Sbjct: 1739 SDAGVYICTCRNLHQSNTSR-AELLVTEAP----------SKPITVTVEEQRSQSVRPGA 1787
Query: 243 TLVLQCVAVG-SPIPHYQWFK---NELPL-THETKKLYMVPYVDLEHQGTYWC 290
+ C A SP W + +LP + + + V L GTY C
Sbjct: 1788 DVTFICTAKSKSPAYTLVWTRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVC 1840
Score = 40.8 bits (94), Expect = 0.005
Identities = 34/108 (31%), Positives = 45/108 (41%), Gaps = 17/108 (15%)
Query: 97 GEKGCTVTELSDFLQAMEHTEVLQLLSP--------PGIK--ITVNPESKAVLAGQFVKL 146
GE C VT S L+A VL + P PG+ I + S V GQ + L
Sbjct: 2889 GEYSCQVTGSSGTLEA----SVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDL 2944
Query: 147 CCRATGHPFVQYQWFKMNKEIP---NGNTSELIFNAVHVKDAGFYVCR 191
C G Q W+K +P + S+L + V D+G YVCR
Sbjct: 2945 NCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRLHLVSPADSGEYVCR 2992
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 61.2 bits (147), Expect = 4e-09
Identities = 55/221 (24%), Positives = 95/221 (42%), Gaps = 32/221 (14%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFN 178
+ +L PP I T P +V+ + V L C+ G PF WFK K + G+ + + +
Sbjct: 1446 IDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLD 1505
Query: 179 ---AVHVKDA-----GFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQIC 230
+H+K+A G Y C V+N + Q + S+ G + +
Sbjct: 1506 RGQVLHLKNARRNDKGRYQCTVSN------AAGKQAKDIKLTIYIPPSIKGGNVT----- 1554
Query: 231 VEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYM-------VPYVDLE 283
T ++ S + L+C G P+P W+K+ P+ ++ LY+ +P +
Sbjct: 1555 ---TDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVS 1611
Query: 284 HQGTYWCHVYN-DRDSQDSKKVEIIIDEL--NNLGHPDNKE 321
TY CHV N ++ S V++ + + NL P NK+
Sbjct: 1612 DSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQ 1652
Score = 55.1 bits (131), Expect = 3e-07
Identities = 47/161 (29%), Positives = 69/161 (42%), Gaps = 28/161 (17%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSEL--- 175
L + PP + P +VL G+ V+L C A G P QW K K I +G T +
Sbjct: 3239 LSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVS 3298
Query: 176 -------IFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQ 228
I+ A+ D G Y C V N E + L+V P ++ G +
Sbjct: 3299 ANGSTLNIYGAL-TSDTGKYTC-VATNPAGEEDRIFNLNVYVTP-----TIRGNKDE--- 3348
Query: 229 ICVEPTSQKLMP--GSTLVLQCVAVGSPIPHYQWFKNELPL 267
++KLM +++ ++C A G+P P W KN LPL
Sbjct: 3349 ------AEKLMTLVDTSINIECRATGTPPPQINWLKNGLPL 3383
Score = 52.8 bits (125), Expect = 1e-06
Identities = 45/159 (28%), Positives = 70/159 (44%), Gaps = 24/159 (15%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGN----TSE 174
L + PP K+TV P++++ G V + C ATG+P + W + I + TS+
Sbjct: 606 LTVQEPP--KVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSD 663
Query: 175 --LIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVE 232
L KDAG Y C +N+ + Q S L + P+ V +S+L + +
Sbjct: 664 GTLFIKNAAPKDAGIYGCLASNSAGTD-KQNSTLRYIEAPKLM------VVQSELLVAL- 715
Query: 233 PTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHET 271
G V++C G P P +WFK +L L T
Sbjct: 716 --------GDITVMECKTSGIPPPQVKWFKGDLELRPST 746
Score = 50.1 bits (118), Expect = 8e-06
Identities = 48/205 (23%), Positives = 81/205 (39%), Gaps = 30/205 (14%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFN 178
L++ PP IK + +VL Q L C G P W+K N ++ +T + + N
Sbjct: 1353 LKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNN 1412
Query: 179 AVHVK-------DAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICV 231
+K DAG Y C+ N ++ +DV P ++ G +
Sbjct: 1413 GKILKLFRATPEDAGRYSCKA-INIAGTSQKYFNIDVLVPP-----TIIGTN-------- 1458
Query: 232 EPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEH------- 284
P ++ + L+C G+P P WFK+ PL + ++ + H
Sbjct: 1459 FPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRN 1518
Query: 285 -QGTYWCHVYNDRDSQDSKKVEIII 308
+G Y C V N Q +K +++ I
Sbjct: 1519 DKGRYQCTVSNAAGKQ-AKDIKLTI 1542
Score = 47.8 bits (112), Expect = 4e-05
Identities = 64/299 (21%), Positives = 112/299 (37%), Gaps = 42/299 (14%)
Query: 92 LLKLMGEKGCTVTELSDFLQAMEHTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRAT 151
LL+ G C T + + +H + L + PP ++ ++ VL V+L C+A
Sbjct: 1889 LLEDAGRYTCVATNAAG--ETQQHIQ-LHVHEPPSLEDAGKMLNETVLVSNPVQLECKAA 1945
Query: 152 GHPFVQYQWFKMNKEIPNGNTSELIFN--------AVHVKDAGFYVC-RVNNNFTFEFSQ 202
G+P W+K N+ + +G+TS N + + DAG Y C +N+ E
Sbjct: 1946 GNPVPVITWYKDNR-LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFY 2004
Query: 203 WSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFK 262
Q+ V S+ G + + P L+C A G P P W K
Sbjct: 2005 SLQVHVAP-------SISGSNNMVAVVVNNPVR----------LECEARGIPAPSLTWLK 2047
Query: 263 NELPLTHETK--------KLYMVPYVDLEHQGTYWCHVYNDRDSQDSKKVEIIIDELNNL 314
+ P++ + ++ + + G Y C N + + N +
Sbjct: 2048 DGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIM 2107
Query: 315 GHPDNKEQTTDQ--PLAKDKVALLIGNMNYRE--HPKLKAPLVDVYELTNLLRQLDFKV 369
G N Q L A+ + + + HP LK P + + E ++L+ D +V
Sbjct: 2108 GEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQV 2166
Score = 47.8 bits (112), Expect = 4e-05
Identities = 42/173 (24%), Positives = 66/173 (38%), Gaps = 28/173 (16%)
Query: 132 NPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNA-------VHVKD 184
+PE+ +V+ V L C A+G P WFK + N+ ++ ++D
Sbjct: 2392 SPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMED 2451
Query: 185 AGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTL 244
AG Y C V N E + L V P V E+ L+ K+ ++
Sbjct: 2452 AGQYTCVVRNAAGEERKIFG-LSVLVPPHI-------VGENTLE------DVKVKEKQSV 2497
Query: 245 VLQCVAVGSPIPHYQWFKNELPLTHETK-------KLYMVPYVDLEHQGTYWC 290
L C G+P+P W K+ PL + + + V + H G Y C
Sbjct: 2498 TLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTC 2550
Score = 47.8 bits (112), Expect = 4e-05
Identities = 56/188 (29%), Positives = 71/188 (37%), Gaps = 40/188 (21%)
Query: 124 PPGIK-----ITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPN-------GN 171
PP I+ TVN S+A+L C A G P W K N + N
Sbjct: 4168 PPRIRSTEGHYTVNENSQAILP-------CVADGIPTPAINWKKDNVLLANLLGKYTAEP 4220
Query: 172 TSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICV 231
ELI V ++D+GFY C V NN E + L V +P +F VS +K
Sbjct: 4221 YGELILENVVLEDSGFYTC-VANNAAGEDTHTVSLTVHVLP-TFTELPGDVSLNK----- 4273
Query: 232 EPTSQKLMPGSTLVLQCVAVGSPIPHYQW-FKNELPLTH----ETKKLYMVPYVDLEHQG 286
G L L C A G P+P W F N + H ++ V E G
Sbjct: 4274 ---------GEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSG 4324
Query: 287 TYWCHVYN 294
TY C N
Sbjct: 4325 TYVCTAEN 4332
Score = 47.0 bits (110), Expect = 7e-05
Identities = 39/150 (26%), Positives = 62/150 (41%), Gaps = 24/150 (16%)
Query: 133 PESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIP------NGNTSELIFNAVHVKDAG 186
P ++ G+ ++L C+ATG P + W N IP NG+ SEL+ V +D+G
Sbjct: 4266 PGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGH-SELVIERVSKEDSG 4324
Query: 187 FYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVL 246
YVC N+ F V I + + +EP G +L
Sbjct: 4325 TYVCTAENSVGF---------VKAIGFVYVKEPPVFKGDYPSNWIEPL------GGNAIL 4369
Query: 247 QCVAVGSPIPHYQWFKN--ELPLTHETKKL 274
C G P P QW + ++ ++H ++L
Sbjct: 4370 NCEVKGDPTPTIQWNRKGVDIEISHRIRQL 4399
Score = 45.8 bits (107), Expect = 2e-04
Identities = 51/221 (23%), Positives = 89/221 (40%), Gaps = 34/221 (15%)
Query: 122 LSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIP---------NGNT 172
LSP +KI VN + L C A P W+K + + NG+T
Sbjct: 2679 LSPKEVKIKVN---------NTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHT 2729
Query: 173 SELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVE 232
++ + D G Y C V +N E +++ +P SFQ+ + + L
Sbjct: 2730 LQI--KEAQISDTGRYTC-VASNIAGEDELDFDVNI-QVPPSFQKLWE--IGNMLDTGRN 2783
Query: 233 PTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYM-------VPYVDLEHQ 285
++ ++ + + L C +P P W+K+ PLT K L + +P +E
Sbjct: 2784 GEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDA 2843
Query: 286 GTYWCHVYNDRDSQDSKK--VEIIIDELNNLGHPDNKEQTT 324
G Y C N+ +DS + V +++ + + D E+ T
Sbjct: 2844 GRYTCVAVNEA-GEDSLQYDVRVLVPPIIKGANSDLPEEVT 2883
Score = 45.1 bits (105), Expect = 3e-04
Identities = 47/187 (25%), Positives = 72/187 (38%), Gaps = 31/187 (16%)
Query: 124 PPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEI---------PNGNTSE 174
PP + I E+ V+ F+ L C +G P W K + I P G T +
Sbjct: 2963 PPSV-IGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQ 3021
Query: 175 LIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPT 234
+I V D G Y C + N E + L V +P S + D SES + V
Sbjct: 3022 II--RAKVSDGGEYTC-IAINQAGESKKKFSLTVY-VPPSIK---DHDSESLSVVNVRE- 3073
Query: 235 SQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETK-------KLYMVPYVDLEHQGT 287
G+++ L+C + P P W+KN +T T ++ + ++ G
Sbjct: 3074 ------GTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQ 3127
Query: 288 YWCHVYN 294
Y C N
Sbjct: 3128 YVCRAIN 3134
Score = 45.1 bits (105), Expect = 3e-04
Identities = 49/222 (22%), Positives = 85/222 (38%), Gaps = 33/222 (14%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEI---------PN 169
LQ+ +PP + ++ E VL G + C G P W + + + +
Sbjct: 3428 LQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTH 3487
Query: 170 GNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQI 229
G +L+ +D+G Y C + +N E S+ L V + P ++G SE +I
Sbjct: 3488 GMVLQLL--KAETEDSGKYTC-IASNEAGEVSKHFILKVLEPPH-----ING-SEEHEEI 3538
Query: 230 CVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETK-------KLYMVPYVDL 282
V + + L L C+A G P P W K+ PL + ++ + +
Sbjct: 3539 SV-------IVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQV 3591
Query: 283 EHQGTYWCHVYNDRDSQDSKKVEIIIDELNNLGHPDNKEQTT 324
E G Y C + + D K+ + + N+ D T
Sbjct: 3592 EDTGRYTC-LASSPAGDDDKEYLVRVHVPPNIAGTDEPRDIT 3632
Score = 43.9 bits (102), Expect = 6e-04
Identities = 47/193 (24%), Positives = 66/193 (34%), Gaps = 36/193 (18%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSE---- 174
LQ+ PP I P + V+ L C ATG P W K N + N + ++
Sbjct: 3798 LQVHVPPSI--APGPTNMTVIVNVQTTLACEATGIPKPSINWRK-NGHLLNVDQNQNSYR 3854
Query: 175 ------LIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQ 228
L+ + V D Y C V N + +R+VD +
Sbjct: 3855 LLSSGSLVIISPSVDDTATYECTVTNGAGDD----------------KRTVDLTVQVPPS 3898
Query: 229 ICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHE-------TKKLYMVPYVD 281
I EPT + + V+ C A G P P W KN + L + +
Sbjct: 3899 IADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQ 3958
Query: 282 LEHQGTYWCHVYN 294
L H G Y C N
Sbjct: 3959 LNHAGRYTCVARN 3971
Score = 42.4 bits (98), Expect = 0.002
Identities = 48/216 (22%), Positives = 78/216 (36%), Gaps = 35/216 (16%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNK-----------EI 167
L + SPP P ++ G V L C G+P +W +++ I
Sbjct: 787 LDVGSPP--VFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSI 844
Query: 168 PNGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKL 227
T L + D G Y+C N F I +V G+ +
Sbjct: 845 SQLRTGALFILNLWASDKGTYICEAENQFG------------KIQSETTVTVTGLVAPLI 892
Query: 228 QICVEPTSQKLMPGSTLVLQCVAV-GSPIPHYQWFKNELPL------THETKKLYMVPYV 280
I P+ ++ G L L C + G+PIP +W KN L T + + V
Sbjct: 893 GI--SPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERV 950
Query: 281 DLEHQGTYWCHVYNDRDSQDSKKVEIIIDELNNLGH 316
L+ G Y C V ++ ++K +++ L + H
Sbjct: 951 QLQDGGEYTC-VASNVAGTNNKTTSVVVHVLPTIQH 985
Score = 42.0 bits (97), Expect = 0.002
Identities = 39/157 (24%), Positives = 65/157 (41%), Gaps = 22/157 (14%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFN 178
L + PP IK +VL +KL C G P W+K + I + + + I
Sbjct: 1540 LTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDK 1599
Query: 179 AVH-------VKDAGFYVCRVNNNF-TFEFSQWSQLDVCDIPESFQRSVDGVSESKLQIC 230
+ V D+ Y C V N T E S +DV +P + ++
Sbjct: 1600 GQYLHIPRAQVSDSATYTCHVANVAGTAEKS--FHVDVY-VPPMIEGNL----------- 1645
Query: 231 VEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPL 267
P +++++ +L L+C A G+P P W K+ +P+
Sbjct: 1646 ATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPV 1682
Score = 42.0 bits (97), Expect = 0.002
Identities = 44/169 (26%), Positives = 76/169 (44%), Gaps = 31/169 (18%)
Query: 119 LQLLSPPGIKITVNPESKAVLA--GQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSEL- 175
L + PP I+ PE + ++ V L C ATG P W K +K I N ++ E+
Sbjct: 3145 LNVYVPPSIE---GPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVR 3201
Query: 176 ---------IFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESK 226
I + H D+G Y C + +N + ++ L + +P S V+ ++
Sbjct: 3202 ILSGGSKLQIARSQH-SDSGNYTC-IASNMEGKAQKYYFLSI-QVPPS-------VAGAE 3251
Query: 227 LQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPL-THETKKL 274
+ P+ ++ G + L C A G P P QW K+ P+ + ET+++
Sbjct: 3252 I-----PSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERI 3295
Score = 42.0 bits (97), Expect = 0.002
Identities = 49/181 (27%), Positives = 65/181 (35%), Gaps = 30/181 (16%)
Query: 144 VKLCCRATGHPFVQYQWFKMNKEIPNG------NTSELIFNAVHVKDAGFYVCRVNNNFT 197
+ L C A G P W K + I ++ L V DAG Y C N
Sbjct: 4096 ITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAAN--V 4153
Query: 198 FEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPH 257
S S +P RS +G V SQ ++P CVA G P P
Sbjct: 4154 AGSSSTSTKLTVHVPPRI-RSTEG------HYTVNENSQAILP-------CVADGIPTPA 4199
Query: 258 YQWFKNELPLTHETKKLYMVPY-------VDLEHQGTYWCHVYNDRDSQDSKKVEIIIDE 310
W K+ + L + K PY V LE G Y C V N+ +D+ V + +
Sbjct: 4200 INWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTC-VANNAAGEDTHTVSLTVHV 4258
Query: 311 L 311
L
Sbjct: 4259 L 4259
Score = 41.6 bits (96), Expect = 0.003
Identities = 41/191 (21%), Positives = 72/191 (37%), Gaps = 30/191 (15%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFN 178
+ +L PP I+ V+ ++L C TG P W K + I + +++ N
Sbjct: 1727 VDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLN 1786
Query: 179 A-------VHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICV 231
V + G Y C N ++ +P + + S G+SE ++ +
Sbjct: 1787 GRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEV--TVHVPPTIKSS--GLSE-RVVVKY 1841
Query: 232 EPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLT--------HETKKLYMVPYVDLE 283
+P + LQC+A G P P W K++ P+ + ++ + LE
Sbjct: 1842 KPVA----------LQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLE 1891
Query: 284 HQGTYWCHVYN 294
G Y C N
Sbjct: 1892 DAGRYTCVATN 1902
Score = 41.6 bits (96), Expect = 0.003
Identities = 42/165 (25%), Positives = 64/165 (38%), Gaps = 24/165 (14%)
Query: 119 LQLLSPPGIKITVN--PESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELI 176
+++L PP IK + PE VL + + C ++G P + W K + + + + +
Sbjct: 2863 VRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFL 2922
Query: 177 FNA-------VHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQI 229
N + D G YVC V N ++ L+V P SV G L +
Sbjct: 2923 SNGRILQILNTQITDIGRYVC-VAENTAGSAKKYFNLNVHVPP-----SVIGPKSENLTV 2976
Query: 230 CVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKL 274
V + + L C G P P W KNE P+ T L
Sbjct: 2977 VVN---------NFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTL 3012
Score = 40.8 bits (94), Expect = 0.005
Identities = 42/151 (27%), Positives = 60/151 (39%), Gaps = 19/151 (12%)
Query: 126 GIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFK------MNKEI---PNGNTSELI 176
G+ NPE V+ L C A +P WFK N+ I P G T +++
Sbjct: 2575 GVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQIL 2634
Query: 177 FNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQ 236
NA +AG Y C V N E + ++ V P + + G S P
Sbjct: 2635 -NAQE-DNAGRYSC-VATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLS-------PKEV 2684
Query: 237 KLMPGSTLVLQCVAVGSPIPHYQWFKNELPL 267
K+ +TL L+C A P W+K+ PL
Sbjct: 2685 KIKVNNTLTLECEAYAIPSASLSWYKDGQPL 2715
Score = 39.7 bits (91), Expect = 0.011
Identities = 64/277 (23%), Positives = 99/277 (35%), Gaps = 70/277 (25%)
Query: 78 SLKVLEPEGSPSLCLLKLMGEKGCTVTELS-DFLQAMEHTEVLQLLSPPGIKITVNPESK 136
S+K+ E S S L C T ++ + QA++ L + PP KI P+
Sbjct: 1134 SMKITETRTSDSGMYL-------CVATNIAGNVTQAVK----LNVHVPP--KIQRGPKHL 1180
Query: 137 AVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAVHVKDAGFYVCRVNNNF 196
V GQ V + C A G P W K G ++ L+ HV N +
Sbjct: 1181 KVQVGQRVDIPCNAQGTPLPVITWSK-------GGSTMLVDGEHHVS---------NPDG 1224
Query: 197 TFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVE--PTSQKLMPGSTLVLQ------- 247
T Q + D I ++ G E+++ + V+ PT + L P Q
Sbjct: 1225 TLSIDQATPSD-AGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQR 1283
Query: 248 ----CVAVGSPIPHYQWFKNELPLTH--------ETKKLYMVPYVDLEHQGTYWCHVYND 295
C A G+P P +W N LT E L ++ V G Y C N+
Sbjct: 1284 IEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNE 1343
Query: 296 ------------------RDSQDSKKVEIIIDELNNL 314
+D + V +++++L NL
Sbjct: 1344 AGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNL 1380
Score = 39.7 bits (91), Expect = 0.011
Identities = 42/156 (26%), Positives = 54/156 (34%), Gaps = 18/156 (11%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELI-- 176
L +L PP I E V Q V L C TG+P + W K + + +I
Sbjct: 2472 LSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISG 2531
Query: 177 -----FNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICV 231
V V G Y C ++ + +S L+V P DG E I
Sbjct: 2532 GRFLQITNVQVPHTGRYTCLASSPAGHKSRSFS-LNVFVSPTIAGVGSDGNPEDVTVILN 2590
Query: 232 EPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPL 267
PTS L C A P WFK+ PL
Sbjct: 2591 SPTS----------LVCEAYSYPPATITWFKDGTPL 2616
Score = 39.7 bits (91), Expect = 0.011
Identities = 37/153 (24%), Positives = 53/153 (34%), Gaps = 25/153 (16%)
Query: 118 VLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIF 177
+L + PP IK P+S +L + L C A G P + W K + + I
Sbjct: 3706 ILTVNVPPNIK--GGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSIL 3763
Query: 178 N-------AVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQIC 230
+ HV D G Y+C N + +R +D I
Sbjct: 3764 ENGFLHIQSAHVTDTGRYLCMATN----------------AAGTDRRRIDLQVHVPPSIA 3807
Query: 231 VEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKN 263
PT+ ++ L C A G P P W KN
Sbjct: 3808 PGPTNMTVIVNVQTTLACEATGIPKPSINWRKN 3840
Score = 39.3 bits (90), Expect = 0.015
Identities = 42/167 (25%), Positives = 59/167 (35%), Gaps = 28/167 (16%)
Query: 101 CTVTELSDFLQAMEHTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQW 160
CT F++A+ V + PP K L G + L C G P QW
Sbjct: 4328 CTAENSVGFVKAIGFVYVKE---PPVFKGDYPSNWIEPLGGNAI-LNCEVKGDPTPTIQW 4383
Query: 161 FKMNKEIPN-------GNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPE 213
+ +I GN S I+ V+ +DAG Y C N
Sbjct: 4384 NRKGVDIEISHRIRQLGNGSLAIYGTVN-EDAGDYTCVATNEAGV--------------- 4427
Query: 214 SFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQW 260
+RS+ +S I +EP + G ++L C A G P P W
Sbjct: 4428 -VERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITW 4473
Score = 38.5 bits (88), Expect = 0.025
Identities = 33/153 (21%), Positives = 61/153 (39%), Gaps = 21/153 (13%)
Query: 118 VLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPN-------G 170
+L++L PP I + E +V+ ++L C A+G P + W K + +P G
Sbjct: 3520 ILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG 3579
Query: 171 NTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQIC 230
L + V+D G Y C ++ + ++ L +P ++ G
Sbjct: 3580 GGEVLRISTAQVEDTGRYTCLASSPAGDDDKEY--LVRVHVPP----NIAGTD------- 3626
Query: 231 VEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKN 263
EP ++ + L+C + P P W +N
Sbjct: 3627 -EPRDITVLRNRQVTLECKSDAVPPPVITWLRN 3658
Score = 38.1 bits (87), Expect = 0.033
Identities = 40/176 (22%), Positives = 63/176 (35%), Gaps = 28/176 (15%)
Query: 134 ESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELI-------FNAVHVKDAG 186
E L + + CRATG P Q W K +P + L+ V D
Sbjct: 3350 EKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVA 3409
Query: 187 FYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVL 246
Y C +N + ++ L V P + S+ G E ++ GS+ +
Sbjct: 3410 VYTCVASNRAGVDNKHYN-LQVF-APPNMDNSM-GTEEI-----------TVLKGSSTSM 3455
Query: 247 QCVAVGSPIPHYQWFKNELPL---THETKKLY----MVPYVDLEHQGTYWCHVYND 295
C+ G+P P W ++ PL H T + + + E G Y C N+
Sbjct: 3456 ACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNE 3511
Score = 35.8 bits (81), Expect = 0.16
Identities = 31/148 (20%), Positives = 54/148 (36%), Gaps = 23/148 (15%)
Query: 132 NPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEI---------PNGNTSELIFNAVHV 182
N E+K V+ + L C P W+K + P G ++ V
Sbjct: 2783 NGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQI--PRAKV 2840
Query: 183 KDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGS 242
+DAG Y C N + Q+ D+ + G + P ++
Sbjct: 2841 EDAGRYTCVAVNEAGEDSLQY------DVRVLVPPIIKGANSDL------PEEVTVLVNK 2888
Query: 243 TLVLQCVAVGSPIPHYQWFKNELPLTHE 270
+ +++C++ GSP P W K+ PL +
Sbjct: 2889 SALIECLSSGSPAPRNSWQKDGQPLLED 2916
Score = 35.4 bits (80), Expect = 0.21
Identities = 36/163 (22%), Positives = 58/163 (35%), Gaps = 30/163 (18%)
Query: 146 LCCRATGHPFVQYQWFKMN-KEIPNGNTSELIFN------AVHVKDAGFYVCRVNNNFTF 198
+ C A+G PF W K + +P G+ ++ + A + AG Y C N
Sbjct: 3916 ITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARN---- 3971
Query: 199 EFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHY 258
S R V I +P+ ++ + ++L C A G+P P
Sbjct: 3972 ------------AAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPFI 4019
Query: 259 QWFKNELPLTHETKKLYMVPYVDL-------EHQGTYWCHVYN 294
W K + + + ++P L E GTY C N
Sbjct: 4020 TWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQN 4062
Score = 33.9 bits (76), Expect = 0.62
Identities = 50/220 (22%), Positives = 74/220 (33%), Gaps = 48/220 (21%)
Query: 98 EKGCTVTELSDFLQAMEHTEVLQLLSPPGIKITVNPESKAVLAGQFVKL-CCRATGHPFV 156
+KG + E + ++ + + I ++P V+ GQ + L C G+P
Sbjct: 861 DKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIP 920
Query: 157 QYQWFK------MNKEIPNGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCD 210
+ +W K N I + L V ++D G Y C +N
Sbjct: 921 ERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASN---------------- 964
Query: 211 IPESFQRSVDGVSESKLQICVE--PTSQ------KLMPGSTLVLQCVAVGSPIPHYQWF- 261
V G + + V PT Q + G + L C A G+P P W
Sbjct: 965 --------VAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSK 1016
Query: 262 KNELPLTHETK-------KLYMVPYVDLEHQGTYWCHVYN 294
K EL T K LY+V E G Y C N
Sbjct: 1017 KGELISTSSAKFSAGADGSLYVVS-PGGEESGEYVCTATN 1055
Score = 33.9 bits (76), Expect = 0.62
Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 6/90 (6%)
Query: 97 GEKGCTVTELSDFLQAMEHTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFV 156
G+ C T + +E + L L SPP IT+ P + AG + L C+ATG P
Sbjct: 4415 GDYTCVATNEAG---VVERSMSLTLQSPP--IITLEPVETVINAGGKIILNCQATGEPQP 4469
Query: 157 QYQWFKMNKEIP-NGNTSELIFNAVHVKDA 185
W + I + + L N++++ DA
Sbjct: 4470 TITWSRQGHSISWDDRVNVLSNNSLYIADA 4499
Score = 31.6 bits (70), Expect = 3.1
Identities = 35/140 (25%), Positives = 46/140 (32%), Gaps = 23/140 (16%)
Query: 128 KITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGN-------TSELIFNAV 180
K+ V V G + C+ +G P Q +WFK + E+ L
Sbjct: 703 KLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQET 762
Query: 181 HVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMP 240
DAG Y C V N + LDV P Q EP +
Sbjct: 763 QDLDAGDYTC-VAINEAGRATGKITLDVGSPPVFIQ---------------EPADVSMEI 806
Query: 241 GSTLVLQCVAVGSPIPHYQW 260
GS + L C G P P +W
Sbjct: 807 GSNVTLPCYVQGYPEPTIKW 826
Score = 31.6 bits (70), Expect = 3.1
Identities = 37/161 (22%), Positives = 60/161 (37%), Gaps = 33/161 (20%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIP-------NGN 171
L++ PP I ++ +VL Q V+L C++ P W K + + N
Sbjct: 2098 LRVYVPPNIM--GEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISEN 2155
Query: 172 TSELIFNAVHVKDAGFYVCRVNN-----NFTFEFSQWSQLDVCDIPESFQRSVDGVSESK 226
S L V+D G Y C N + + W +P + G S+
Sbjct: 2156 RSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW-------VPPNI-----GGSDEL 2203
Query: 227 LQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPL 267
Q+ V + G+ + L C + G P P+ W K P+
Sbjct: 2204 TQLTV-------IEGNLISLLCESSGIPPPNLIWKKKGSPV 2237
Score = 31.6 bits (70), Expect = 3.1
Identities = 32/150 (21%), Positives = 53/150 (35%), Gaps = 29/150 (19%)
Query: 124 PPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELI------- 176
PP I T P VL + V L C++ P W + + + ++
Sbjct: 3619 PPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQ 3678
Query: 177 FNAVHVKDAGFYVCRVNN---NFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEP 233
N + D Y C +N T EF + ++P + + P
Sbjct: 3679 INNADLGDTANYTCVASNIAGKTTREF-----ILTVNVPPNIKGG--------------P 3719
Query: 234 TSQKLMPGSTLVLQCVAVGSPIPHYQWFKN 263
S ++ + VL+C+A G P P W K+
Sbjct: 3720 QSLVILLNKSTVLECIAEGVPTPRITWRKD 3749
Score = 31.2 bits (69), Expect = 4.0
Identities = 40/206 (19%), Positives = 63/206 (30%), Gaps = 51/206 (24%)
Query: 124 PPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTS---------E 174
PP I + V+ G + L C ++G P W K + + +
Sbjct: 2194 PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQ 2253
Query: 175 LIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVS--ESKLQICVE 232
L + DA Y C +N V G + E LQ+ +
Sbjct: 2254 LQISIAEKSDAALYSCVASN------------------------VAGTAKKEYNLQVYIR 2289
Query: 233 PTSQK---------LMPGSTLVLQCVAVGSPIPHYQWFKNELPLTH-------ETKKLYM 276
PT + G ++ L+C G P P W K+ PL + +
Sbjct: 2290 PTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQ 2349
Query: 277 VPYVDLEHQGTYWCHVYNDRDSQDSK 302
+ + + G Y C N D K
Sbjct: 2350 LKNIHVSDTGRYVCVAVNVAGMTDKK 2375
>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
isoform 2 precursor [Homo sapiens]
Length = 1910
Score = 60.5 bits (145), Expect = 6e-09
Identities = 41/151 (27%), Positives = 67/151 (44%), Gaps = 21/151 (13%)
Query: 129 ITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFK----MNKEIPNGNTSELIFNAVHVK- 183
I + P+ K V + + C A+G+P + WFK ++ NG +L A+ ++
Sbjct: 137 IDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIES 196
Query: 184 ----DAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLM 239
D G Y C N+ +S + L V V + + P S ++M
Sbjct: 197 SEETDQGKYECVATNSAGVRYSSPANLYV------------RVRRVAPRFSILPMSHEIM 244
Query: 240 PGSTLVLQCVAVGSPIPHYQWFKNELPLTHE 270
PG + + CVAVGSP+P+ +W + LT E
Sbjct: 245 PGGNVNITCVAVGSPMPYVKWMQGAEDLTPE 275
Score = 37.7 bits (86), Expect = 0.043
Identities = 37/149 (24%), Positives = 61/149 (40%), Gaps = 26/149 (17%)
Query: 133 PESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAV-----------H 181
P+ + ++G C+ATG P + W K K++ + + F+
Sbjct: 39 PKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRT 98
Query: 182 VKDAGFYVCRVNNNFTFEFSQWSQLDVC---DIPESFQRSVDGVSESKLQICVEPTSQKL 238
+D Y C V N E + ++L V +P F ++D + K+ VE T
Sbjct: 99 PRDENVYEC-VAQNSVGEITVHAKLTVLREDQLPSGFP-NIDMGPQLKV---VERT---- 149
Query: 239 MPGSTLVLQCVAVGSPIPHYQWFKNELPL 267
T + C A G+P P WFK+ LP+
Sbjct: 150 ---RTATMLCAASGNPDPEITWFKDFLPV 175
>gi|104487295 protein tyrosine phosphatase, receptor type, sigma
isoform 3 precursor [Homo sapiens]
Length = 1501
Score = 60.5 bits (145), Expect = 6e-09
Identities = 41/151 (27%), Positives = 67/151 (44%), Gaps = 21/151 (13%)
Query: 129 ITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFK----MNKEIPNGNTSELIFNAVHVK- 183
I + P+ K V + + C A+G+P + WFK ++ NG +L A+ ++
Sbjct: 137 IDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIES 196
Query: 184 ----DAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLM 239
D G Y C N+ +S + L V V + + P S ++M
Sbjct: 197 SEETDQGKYECVATNSAGVRYSSPANLYV------------RVRRVAPRFSILPMSHEIM 244
Query: 240 PGSTLVLQCVAVGSPIPHYQWFKNELPLTHE 270
PG + + CVAVGSP+P+ +W + LT E
Sbjct: 245 PGGNVNITCVAVGSPMPYVKWMQGAEDLTPE 275
Score = 37.7 bits (86), Expect = 0.043
Identities = 37/149 (24%), Positives = 61/149 (40%), Gaps = 26/149 (17%)
Query: 133 PESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAV-----------H 181
P+ + ++G C+ATG P + W K K++ + + F+
Sbjct: 39 PKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRT 98
Query: 182 VKDAGFYVCRVNNNFTFEFSQWSQLDVC---DIPESFQRSVDGVSESKLQICVEPTSQKL 238
+D Y C V N E + ++L V +P F ++D + K+ VE T
Sbjct: 99 PRDENVYEC-VAQNSVGEITVHAKLTVLREDQLPSGFP-NIDMGPQLKV---VERT---- 149
Query: 239 MPGSTLVLQCVAVGSPIPHYQWFKNELPL 267
T + C A G+P P WFK+ LP+
Sbjct: 150 ---RTATMLCAASGNPDPEITWFKDFLPV 175
>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform
2 precursor [Homo sapiens]
Length = 1899
Score = 59.7 bits (143), Expect = 1e-08
Identities = 41/151 (27%), Positives = 68/151 (45%), Gaps = 21/151 (13%)
Query: 129 ITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFK----MNKEIPNGNTSELIFNAVHVK- 183
I + P+ K V + + C A+G+P + WFK ++ NG +L A+ ++
Sbjct: 128 IDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSGALQIEQ 187
Query: 184 ----DAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLM 239
D G Y C N+ +S + L V V + + PT+ ++M
Sbjct: 188 SEESDQGKYECVATNSAGTRYSAPANLYV------------RVRRVPPRFSIPPTNHEIM 235
Query: 240 PGSTLVLQCVAVGSPIPHYQWFKNELPLTHE 270
PG ++ + CVAVGSP+P+ +W LT E
Sbjct: 236 PGGSVNITCVAVGSPMPYVKWMLGAEDLTPE 266
Score = 45.8 bits (107), Expect = 2e-04
Identities = 45/159 (28%), Positives = 68/159 (42%), Gaps = 28/159 (17%)
Query: 123 SPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPN----------GNT 172
+PP + T P + ++G C+ATG P + W K K++ N G+
Sbjct: 22 TPP--RFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSG 79
Query: 173 SELIFNAVHV-KDAGFYVCRVNNNFTFEFSQWSQLDVC---DIPESFQRSVDGVSESKLQ 228
S L + +D Y C +NN E S ++L V IP F ++D + K+
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNN-VGEISVSTRLTVLREDQIPRGFP-TIDMGPQLKV- 136
Query: 229 ICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPL 267
VE T T + C A G+P P WFK+ LP+
Sbjct: 137 --VERT-------RTATMLCAASGNPDPEITWFKDFLPV 166
>gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo
sapiens]
Length = 2113
Score = 59.7 bits (143), Expect = 1e-08
Identities = 49/186 (26%), Positives = 78/186 (41%), Gaps = 31/186 (16%)
Query: 135 SKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNT-----SELIFNAVHVKDAGFYV 189
S+ V AG V+L C A+G+P +W K + +P + + L + + +D+G Y+
Sbjct: 294 SQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRITGLTISDLRTEDSGTYI 353
Query: 190 CRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCV 249
C V N F L V D L + + P K GST++L C
Sbjct: 354 CEVTNTFG-SAEATGILMVID---------------PLHVTLTPKKLKTGIGSTVILSCA 397
Query: 250 AVGSPIPHYQWFKN-ELPLTHE-------TKKLYMVPYVDLEHQGTYWCHVYNDRDSQDS 301
GSP +W++N EL L E + + ++ H G Y C + R +Q +
Sbjct: 398 LTGSPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQC--FATRKAQTA 455
Query: 302 KKVEII 307
+ II
Sbjct: 456 QDFAII 461
Score = 53.1 bits (126), Expect = 1e-06
Identities = 45/146 (30%), Positives = 68/146 (46%), Gaps = 19/146 (13%)
Query: 175 LIFNAVHVKDA-GFYVCRVNNNFTFEFSQ--WSQLDVCDIPESFQRSVDGVSESKLQICV 231
L + V +DA Y C + ++ E Q ++L V D ES +DG
Sbjct: 242 LYISDVQKEDALSTYRCITKHKYSGETRQSNGARLSVTDPAESIPTILDGFH-------- 293
Query: 232 EPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHE---TKKLYMVPYVDL--EHQG 286
SQ++ G T+ L C A G PIP +W K+ PL + TK++ + DL E G
Sbjct: 294 ---SQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRITGLTISDLRTEDSG 350
Query: 287 TYWCHVYNDRDSQDSKKVEIIIDELN 312
TY C V N S ++ + ++ID L+
Sbjct: 351 TYICEVTNTFGSAEATGILMVIDPLH 376
Score = 46.2 bits (108), Expect = 1e-04
Identities = 42/200 (21%), Positives = 76/200 (38%), Gaps = 31/200 (15%)
Query: 98 EKGCTVTELSDFLQAMEHTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQ 157
+ G + E+++ + E T +L ++ P + +T+ P+ G V L C TG P
Sbjct: 348 DSGTYICEVTNTFGSAEATGILMVIDP--LHVTLTPKKLKTGIGSTVILSCALTGSPEFT 405
Query: 158 YQWFKMNK--------EIPNGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQ-LDV 208
+W++ + I + L+ + +G Y C F +Q +Q +
Sbjct: 406 IRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQC-----FATRKAQTAQDFAI 460
Query: 209 CDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPL- 267
+ + R V SE + PG L C A G+P P W ++ P+
Sbjct: 461 IALEDGTPRIVSSFSEKVVN-----------PGEQFSLMCAAKGAPPPTVTWALDDEPIV 509
Query: 268 ---THETKKLYMVPYVDLEH 284
+H T + M + H
Sbjct: 510 RDGSHRTNQYTMSDGTTISH 529
Score = 34.7 bits (78), Expect = 0.36
Identities = 47/213 (22%), Positives = 80/213 (37%), Gaps = 43/213 (20%)
Query: 101 CTVTELSDFLQAMEHTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQW 160
CT L + + E+ + + PP I+ N + +AG+ + CR G+P+ +W
Sbjct: 545 CTARNL---VGSAEYQARINVRGPPSIRAMRNITA---VAGRDTLINCRVIGYPYYSIKW 598
Query: 161 FKMNKEIPNGNTSELIFNAVHVK--------DAGFYVCRVNNNFTFEFSQWSQLDVCDIP 212
+K +P+ N +++F +K D G Y+C V SQ + V
Sbjct: 599 YKDALLLPD-NHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAV---- 653
Query: 213 ESFQRSVDGVSESKLQICVEPTS-QKLMPGSTLVLQCVAVGSPIP-HYQWFKNELPL--- 267
K+ ++P G L + CV +P W K+ +
Sbjct: 654 -------------KVPPLIQPFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISG 700
Query: 268 ---THETKKL---YMVPYVDLEHQGTYWCHVYN 294
T E+K+ + V L+H G Y C N
Sbjct: 701 SGVTIESKEFMSSLQISSVSLKHNGNYTCIASN 733
Score = 30.8 bits (68), Expect = 5.3
Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 10/66 (15%)
Query: 144 VKLCCRATGHPFVQYQWFKMNKE--IPNG--------NTSELIFNAVHVKDAGFYVCRVN 193
V+L C + G P +W K +++ IP L+ AV +D+G+Y C
Sbjct: 1367 VRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTAT 1426
Query: 194 NNFTFE 199
N F+
Sbjct: 1427 NTGGFD 1432
Score = 30.4 bits (67), Expect = 6.9
Identities = 42/185 (22%), Positives = 70/185 (37%), Gaps = 39/185 (21%)
Query: 147 CCRATGHPFVQYQWFKMNKEIPNGN---------TSELIFNAVHVKDAGFYVCRVNNNFT 197
C ++G ++ W K + I +G+ S L ++V +K G Y C + +N
Sbjct: 677 CVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTC-IASNAA 735
Query: 198 FEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPH 257
S+ QL + +P F V+P +Q + G VL C G P P
Sbjct: 736 ATVSRERQL-IVRVPPRF--------------VVQPNNQDGIYGKAGVLNCSVDGYPPPK 780
Query: 258 YQWFK----------NELPLTHETKKL----YMVPYVDLEHQGTYWCHVYNDRDSQDSKK 303
W + +PLT + L ++ +V E G Y C N + SK
Sbjct: 781 VMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKS 840
Query: 304 VEIII 308
+ + +
Sbjct: 841 MFLTV 845
>gi|104487002 protein tyrosine phosphatase, receptor type, D isoform
5 precursor [Homo sapiens]
Length = 1502
Score = 59.3 bits (142), Expect = 1e-08
Identities = 43/157 (27%), Positives = 72/157 (45%), Gaps = 23/157 (14%)
Query: 129 ITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFK----MNKEIPNGNTSEL------IFN 178
I + P+ K V + + C A+G+P + WFK ++ NG +L I
Sbjct: 128 IDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSGGTPIRG 187
Query: 179 AVHVK-----DAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEP 233
A+ ++ D G Y C N+ +S + L V ++ E V + + P
Sbjct: 188 ALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELRE--------VRRVPPRFSIPP 239
Query: 234 TSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHE 270
T+ ++MPG ++ + CVAVGSP+P+ +W LT E
Sbjct: 240 TNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPE 276
Score = 46.2 bits (108), Expect = 1e-04
Identities = 53/221 (23%), Positives = 84/221 (38%), Gaps = 43/221 (19%)
Query: 123 SPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPN----------GNT 172
+PP + T P + ++G C+ATG P + W K K++ N G+
Sbjct: 22 TPP--RFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSG 79
Query: 173 SELIFNAVHV-KDAGFYVCRVNNNFTFEFSQWSQLDVC---DIPESFQRSVDGVSESKLQ 228
S L + +D Y C +NN E S ++L V IP F ++D + K+
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNN-VGEISVSTRLTVLREDQIPRGFP-TIDMGPQLKV- 136
Query: 229 ICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHET---------------KK 273
VE T T + C A G+P P WFK+ LP+ +
Sbjct: 137 --VERT-------RTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSGGTPIRG 187
Query: 274 LYMVPYVDLEHQGTYWCHVYNDRDSQDSKKVEIIIDELNNL 314
+ + QG Y C N ++ S + + EL +
Sbjct: 188 ALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREV 228
>gi|7657359 contactin 5 isoform long [Homo sapiens]
Length = 1100
Score = 59.3 bits (142), Expect = 1e-08
Identities = 52/178 (29%), Positives = 76/178 (42%), Gaps = 27/178 (15%)
Query: 128 KITVN-PESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNG-----NTSELIFNAVH 181
KI V+ P + G VK+ C A G+P W K+N IP+ + + L V
Sbjct: 301 KIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQAVLEIPNVQ 360
Query: 182 VKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPG 241
+ DAG Y CR N+ + S QL V P ++ D +S G
Sbjct: 361 LDDAGIYECRAENS-RGKNSFRGQLQVYTYPHWVEKLNDTQLDS---------------G 404
Query: 242 STLVLQCVAVGSPIPHYQWFKNELPLTHETK-----KLYMVPYVDLEHQGTYWCHVYN 294
S L +C A G P P Y+W KN +PL+ +++ + M+ V+ G Y C N
Sbjct: 405 SPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNGVLMIHNVNQSDAGMYQCLAEN 462
Score = 54.7 bits (130), Expect = 3e-07
Identities = 47/178 (26%), Positives = 71/178 (39%), Gaps = 26/178 (14%)
Query: 137 AVLAGQFVKLCCRATGH-PFVQYQWF---------KMNKEIPNGNTSELIFNAVHVKDAG 186
+V GQ V L C H P + Y W + ++ + T L + V D G
Sbjct: 206 SVREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVG 265
Query: 187 FYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVS---ESKLQICVEPTSQKLMPGST 243
Y+C V N T V P DGV E K+++ P + G+T
Sbjct: 266 SYICLVKNTVT-------NARVLSPPTPLTLRNDGVMGEYEPKIEVHF-PFTVTAAKGTT 317
Query: 244 LVLQCVAVGSPIPHYQWFK--NELPLTHETKK---LYMVPYVDLEHQGTYWCHVYNDR 296
+ ++C A+G+P+P W K +P +K + +P V L+ G Y C N R
Sbjct: 318 VKMECFALGNPVPTITWMKVNGYIPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSR 375
Score = 42.4 bits (98), Expect = 0.002
Identities = 45/174 (25%), Positives = 62/174 (35%), Gaps = 42/174 (24%)
Query: 144 VKLCCRATGHPFVQYQWFKMNKEIPNGNT--------SELIFNAVHVKDAGFYVCRVNNN 195
V L C G+P Y+W + EI + + +I N KD+G Y C N
Sbjct: 119 VALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIISNPSEAKDSGHYQCLATNT 178
Query: 196 FTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPI 255
S+ + L + R+ VS + G +VL C SP
Sbjct: 179 VGSILSREATLQFAYLGNFSGRTRSAVS--------------VREGQGVVLMC----SPP 220
Query: 256 PH-----YQWFKNELP----------LTHETKKLYMVPYVDLEHQGTYWCHVYN 294
PH Y W NE P ++ ET LY + V G+Y C V N
Sbjct: 221 PHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLY-ISKVQTSDVGSYICLVKN 273
Score = 41.6 bits (96), Expect = 0.003
Identities = 32/136 (23%), Positives = 60/136 (44%), Gaps = 19/136 (13%)
Query: 148 CRATGHPFVQYQWFKMNKEIPNGNTSELI-----FNAVHVKDAGFYVCRVNNNFTFEFSQ 202
C+ATG P Y+W K + + E++ + V+ DAG Y C N + ++
Sbjct: 411 CKATGKPRPTYRWLKNGVPLSPQSRVEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYAS 470
Query: 203 WSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFK 262
++L + +F +++ K I V + +V++C GSP P W K
Sbjct: 471 -AELKILASAPTF-----ALNQLKKTIIVTKDQE-------VVIECKPQGSPKPTISWKK 517
Query: 263 NELPLTHETKKLYMVP 278
+ + E K++ ++P
Sbjct: 518 GDRAV-RENKRIAILP 532
Score = 31.2 bits (69), Expect = 4.0
Identities = 50/216 (23%), Positives = 79/216 (36%), Gaps = 44/216 (20%)
Query: 117 EVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEI--------- 167
E+ L S P + ++ V Q V + C+ G P W K ++ +
Sbjct: 472 ELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAIL 531
Query: 168 PNGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKL 227
P+G+ I NA D G YVCR N F +I S +
Sbjct: 532 PDGSLR--ILNASK-SDEGKYVCRGENVF----------GSAEIIASLS------VKEPT 572
Query: 228 QICVEPTSQKLMPGSTLVLQCVAV--GSPIPHYQWFKNELPLTHETKKLY---------- 275
+I + P +L G ++VL C A+ S + W P+ E + +
Sbjct: 573 RIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASS 632
Query: 276 ---MVPYVDLEHQGTYWCHVYNDRDSQDSKKVEIII 308
M+ + L H G Y C V DS S + E+++
Sbjct: 633 ADLMIRNILLMHAGRYGCRVQTTADSV-SDEAELLV 667
>gi|28373129 contactin 5 isoform short [Homo sapiens]
Length = 1026
Score = 59.3 bits (142), Expect = 1e-08
Identities = 52/178 (29%), Positives = 76/178 (42%), Gaps = 27/178 (15%)
Query: 128 KITVN-PESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNG-----NTSELIFNAVH 181
KI V+ P + G VK+ C A G+P W K+N IP+ + + L V
Sbjct: 227 KIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQAVLEIPNVQ 286
Query: 182 VKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPG 241
+ DAG Y CR N+ + S QL V P ++ D +S G
Sbjct: 287 LDDAGIYECRAENS-RGKNSFRGQLQVYTYPHWVEKLNDTQLDS---------------G 330
Query: 242 STLVLQCVAVGSPIPHYQWFKNELPLTHETK-----KLYMVPYVDLEHQGTYWCHVYN 294
S L +C A G P P Y+W KN +PL+ +++ + M+ V+ G Y C N
Sbjct: 331 SPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNGVLMIHNVNQSDAGMYQCLAEN 388
Score = 54.7 bits (130), Expect = 3e-07
Identities = 47/178 (26%), Positives = 71/178 (39%), Gaps = 26/178 (14%)
Query: 137 AVLAGQFVKLCCRATGH-PFVQYQWF---------KMNKEIPNGNTSELIFNAVHVKDAG 186
+V GQ V L C H P + Y W + ++ + T L + V D G
Sbjct: 132 SVREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVG 191
Query: 187 FYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVS---ESKLQICVEPTSQKLMPGST 243
Y+C V N T V P DGV E K+++ P + G+T
Sbjct: 192 SYICLVKNTVT-------NARVLSPPTPLTLRNDGVMGEYEPKIEVHF-PFTVTAAKGTT 243
Query: 244 LVLQCVAVGSPIPHYQWFK--NELPLTHETKK---LYMVPYVDLEHQGTYWCHVYNDR 296
+ ++C A+G+P+P W K +P +K + +P V L+ G Y C N R
Sbjct: 244 VKMECFALGNPVPTITWMKVNGYIPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSR 301
Score = 42.4 bits (98), Expect = 0.002
Identities = 45/174 (25%), Positives = 62/174 (35%), Gaps = 42/174 (24%)
Query: 144 VKLCCRATGHPFVQYQWFKMNKEIPNGNT--------SELIFNAVHVKDAGFYVCRVNNN 195
V L C G+P Y+W + EI + + +I N KD+G Y C N
Sbjct: 45 VALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIISNPSEAKDSGHYQCLATNT 104
Query: 196 FTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPI 255
S+ + L + R+ VS + G +VL C SP
Sbjct: 105 VGSILSREATLQFAYLGNFSGRTRSAVS--------------VREGQGVVLMC----SPP 146
Query: 256 PH-----YQWFKNELP----------LTHETKKLYMVPYVDLEHQGTYWCHVYN 294
PH Y W NE P ++ ET LY + V G+Y C V N
Sbjct: 147 PHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLY-ISKVQTSDVGSYICLVKN 199
Score = 41.6 bits (96), Expect = 0.003
Identities = 32/136 (23%), Positives = 60/136 (44%), Gaps = 19/136 (13%)
Query: 148 CRATGHPFVQYQWFKMNKEIPNGNTSELI-----FNAVHVKDAGFYVCRVNNNFTFEFSQ 202
C+ATG P Y+W K + + E++ + V+ DAG Y C N + ++
Sbjct: 337 CKATGKPRPTYRWLKNGVPLSPQSRVEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYAS 396
Query: 203 WSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFK 262
++L + +F +++ K I V + +V++C GSP P W K
Sbjct: 397 -AELKILASAPTF-----ALNQLKKTIIVTKDQE-------VVIECKPQGSPKPTISWKK 443
Query: 263 NELPLTHETKKLYMVP 278
+ + E K++ ++P
Sbjct: 444 GDRAV-RENKRIAILP 458
Score = 31.2 bits (69), Expect = 4.0
Identities = 50/216 (23%), Positives = 79/216 (36%), Gaps = 44/216 (20%)
Query: 117 EVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEI--------- 167
E+ L S P + ++ V Q V + C+ G P W K ++ +
Sbjct: 398 ELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAIL 457
Query: 168 PNGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKL 227
P+G+ I NA D G YVCR N F +I S +
Sbjct: 458 PDGSLR--ILNASK-SDEGKYVCRGENVF----------GSAEIIASLS------VKEPT 498
Query: 228 QICVEPTSQKLMPGSTLVLQCVAV--GSPIPHYQWFKNELPLTHETKKLY---------- 275
+I + P +L G ++VL C A+ S + W P+ E + +
Sbjct: 499 RIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASS 558
Query: 276 ---MVPYVDLEHQGTYWCHVYNDRDSQDSKKVEIII 308
M+ + L H G Y C V DS S + E+++
Sbjct: 559 ADLMIRNILLMHAGRYGCRVQTTADSV-SDEAELLV 593
>gi|205830473 sialic acid binding Ig-like lectin 11 isoform 2 [Homo
sapiens]
Length = 602
Score = 59.3 bits (142), Expect = 1e-08
Identities = 44/170 (25%), Positives = 71/170 (41%), Gaps = 9/170 (5%)
Query: 138 VLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGN-----TSELIFNAVHVKDAGFYVCRV 192
V GQF++L C A P W ++ + + + T L V D+G Y CR
Sbjct: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRA 336
Query: 193 NNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVG 252
N + Q L V PE+ + V + + L+ TS ++ G +L L CV
Sbjct: 337 ENRLGSQ-QQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHS 395
Query: 253 SP---IPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWCHVYNDRDSQ 299
SP + +W + P + +P + +EH+G + CH + SQ
Sbjct: 396 SPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQ 445
>gi|205830470 sialic acid binding Ig-like lectin 11 isoform 1 [Homo
sapiens]
Length = 698
Score = 59.3 bits (142), Expect = 1e-08
Identities = 44/170 (25%), Positives = 71/170 (41%), Gaps = 9/170 (5%)
Query: 138 VLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGN-----TSELIFNAVHVKDAGFYVCRV 192
V GQF++L C A P W ++ + + + T L V D+G Y CR
Sbjct: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRA 336
Query: 193 NNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVG 252
N + Q L V PE+ + V + + L+ TS ++ G +L L CV
Sbjct: 337 ENRLGSQ-QQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHS 395
Query: 253 SP---IPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWCHVYNDRDSQ 299
SP + +W + P + +P + +EH+G + CH + SQ
Sbjct: 396 SPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQ 445
>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
isoform 1 precursor [Homo sapiens]
Length = 1948
Score = 58.9 bits (141), Expect = 2e-08
Identities = 43/160 (26%), Positives = 71/160 (44%), Gaps = 26/160 (16%)
Query: 129 ITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFK----MNKEIPNGNTSEL--------- 175
I + P+ K V + + C A+G+P + WFK ++ NG +L
Sbjct: 137 IDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTP 196
Query: 176 IFNAVHVK-----DAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQIC 230
I A+ ++ D G Y C N+ +S + L V ++ E V +
Sbjct: 197 IRGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRELRE--------VRRVAPRFS 248
Query: 231 VEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHE 270
+ P S ++MPG + + CVAVGSP+P+ +W + LT E
Sbjct: 249 ILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPE 288
Score = 37.7 bits (86), Expect = 0.043
Identities = 37/149 (24%), Positives = 61/149 (40%), Gaps = 26/149 (17%)
Query: 133 PESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAV-----------H 181
P+ + ++G C+ATG P + W K K++ + + F+
Sbjct: 39 PKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRT 98
Query: 182 VKDAGFYVCRVNNNFTFEFSQWSQLDVC---DIPESFQRSVDGVSESKLQICVEPTSQKL 238
+D Y C V N E + ++L V +P F ++D + K+ VE T
Sbjct: 99 PRDENVYEC-VAQNSVGEITVHAKLTVLREDQLPSGFP-NIDMGPQLKV---VERT---- 149
Query: 239 MPGSTLVLQCVAVGSPIPHYQWFKNELPL 267
T + C A G+P P WFK+ LP+
Sbjct: 150 ---RTATMLCAASGNPDPEITWFKDFLPV 175
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 58.9 bits (141), Expect = 2e-08
Identities = 50/193 (25%), Positives = 75/193 (38%), Gaps = 35/193 (18%)
Query: 123 SPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKE----------IPNGNT 172
SP + P++ VL G+ V L C ATGHP + W + ++ P+G
Sbjct: 338 SPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGG- 396
Query: 173 SELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVE 232
L V D+G Y C NN +S + + ++ Q V
Sbjct: 397 --LYIQNVVQGDSGEYACSATNNI----------------DSVHATAFIIVQALPQFTVT 438
Query: 233 PTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYM------VPYVDLEHQG 286
P + ++ G T+ QC A G+P P W K L+ + + L + + V L QG
Sbjct: 439 PQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGTLRISGVALHDQG 498
Query: 287 TYWCHVYNDRDSQ 299
Y C N SQ
Sbjct: 499 QYECQAVNIIGSQ 511
Score = 48.9 bits (115), Expect = 2e-05
Identities = 42/186 (22%), Positives = 68/186 (36%), Gaps = 27/186 (14%)
Query: 128 KITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSE--------LIFNA 179
+IT P+ V +G V CRA G+P + W + N E+ S L+
Sbjct: 247 RITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMIQN 306
Query: 180 VHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLM 239
D G Y C N +Q L P ++ ++P + +++
Sbjct: 307 TQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSP------------ARPTFVIQPQNTEVL 354
Query: 240 PGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQ-------GTYWCHV 292
G ++ L+C A G P P W + + ++ + P L Q G Y C
Sbjct: 355 VGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYACSA 414
Query: 293 YNDRDS 298
N+ DS
Sbjct: 415 TNNIDS 420
Score = 42.7 bits (99), Expect = 0.001
Identities = 48/188 (25%), Positives = 77/188 (40%), Gaps = 26/188 (13%)
Query: 97 GEKGCTVTELSDFLQAMEHTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFV 156
GE C+ T D + A ++Q L + TV P+ + V+ GQ V C A G+P
Sbjct: 408 GEYACSATNNIDSVHATAFI-IVQALP----QFTVTPQDRVVIEGQTVDFQCEAKGNPPP 462
Query: 157 QYQWFKMNKEIPNG------NTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCD 210
W K ++ ++ L + V + D G Y C+ N SQ V
Sbjct: 463 VIAWTKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIG------SQKVVAH 516
Query: 211 IPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHE 270
+ + Q V V S P+ + G+ + L C + G P P W K+ + +T E
Sbjct: 517 L--TVQPRVTPVFASI------PSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVT-E 567
Query: 271 TKKLYMVP 278
+ K ++ P
Sbjct: 568 SGKFHISP 575
>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
precursor [Homo sapiens]
Length = 1912
Score = 58.2 bits (139), Expect = 3e-08
Identities = 43/160 (26%), Positives = 72/160 (45%), Gaps = 26/160 (16%)
Query: 129 ITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFK----MNKEIPNGNTSEL--------- 175
I + P+ K V + + C A+G+P + WFK ++ NG +L
Sbjct: 128 IDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTP 187
Query: 176 IFNAVHVK-----DAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQIC 230
I A+ ++ D G Y C N+ +S + L V ++ E V +
Sbjct: 188 IRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELRE--------VRRVPPRFS 239
Query: 231 VEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHE 270
+ PT+ ++MPG ++ + CVAVGSP+P+ +W LT E
Sbjct: 240 IPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPE 279
Score = 45.8 bits (107), Expect = 2e-04
Identities = 45/159 (28%), Positives = 68/159 (42%), Gaps = 28/159 (17%)
Query: 123 SPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPN----------GNT 172
+PP + T P + ++G C+ATG P + W K K++ N G+
Sbjct: 22 TPP--RFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSG 79
Query: 173 SELIFNAVHV-KDAGFYVCRVNNNFTFEFSQWSQLDVC---DIPESFQRSVDGVSESKLQ 228
S L + +D Y C +NN E S ++L V IP F ++D + K+
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNN-VGEISVSTRLTVLREDQIPRGFP-TIDMGPQLKV- 136
Query: 229 ICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPL 267
VE T T + C A G+P P WFK+ LP+
Sbjct: 137 --VERT-------RTATMLCAASGNPDPEITWFKDFLPV 166
>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform
3 precursor [Homo sapiens]
Length = 1903
Score = 58.2 bits (139), Expect = 3e-08
Identities = 43/160 (26%), Positives = 72/160 (45%), Gaps = 26/160 (16%)
Query: 129 ITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFK----MNKEIPNGNTSEL--------- 175
I + P+ K V + + C A+G+P + WFK ++ NG +L
Sbjct: 128 IDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTP 187
Query: 176 IFNAVHVK-----DAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQIC 230
I A+ ++ D G Y C N+ +S + L V ++ E V +
Sbjct: 188 IRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELRE--------VRRVPPRFS 239
Query: 231 VEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHE 270
+ PT+ ++MPG ++ + CVAVGSP+P+ +W LT E
Sbjct: 240 IPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPE 279
Score = 45.8 bits (107), Expect = 2e-04
Identities = 45/159 (28%), Positives = 68/159 (42%), Gaps = 28/159 (17%)
Query: 123 SPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPN----------GNT 172
+PP + T P + ++G C+ATG P + W K K++ N G+
Sbjct: 22 TPP--RFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSG 79
Query: 173 SELIFNAVHV-KDAGFYVCRVNNNFTFEFSQWSQLDVC---DIPESFQRSVDGVSESKLQ 228
S L + +D Y C +NN E S ++L V IP F ++D + K+
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNN-VGEISVSTRLTVLREDQIPRGFP-TIDMGPQLKV- 136
Query: 229 ICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPL 267
VE T T + C A G+P P WFK+ LP+
Sbjct: 137 --VERT-------RTATMLCAASGNPDPEITWFKDFLPV 166
>gi|18860894 protein tyrosine phosphatase, receptor type, D isoform
4 precursor [Homo sapiens]
Length = 1501
Score = 58.2 bits (139), Expect = 3e-08
Identities = 43/160 (26%), Positives = 72/160 (45%), Gaps = 26/160 (16%)
Query: 129 ITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFK----MNKEIPNGNTSEL--------- 175
I + P+ K V + + C A+G+P + WFK ++ NG +L
Sbjct: 128 IDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTP 187
Query: 176 IFNAVHVK-----DAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQIC 230
I A+ ++ D G Y C N+ +S + L V ++ E V +
Sbjct: 188 IRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELRE--------VRRVPPRFS 239
Query: 231 VEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHE 270
+ PT+ ++MPG ++ + CVAVGSP+P+ +W LT E
Sbjct: 240 IPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPE 279
Score = 45.8 bits (107), Expect = 2e-04
Identities = 45/159 (28%), Positives = 68/159 (42%), Gaps = 28/159 (17%)
Query: 123 SPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPN----------GNT 172
+PP + T P + ++G C+ATG P + W K K++ N G+
Sbjct: 22 TPP--RFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSG 79
Query: 173 SELIFNAVHV-KDAGFYVCRVNNNFTFEFSQWSQLDVC---DIPESFQRSVDGVSESKLQ 228
S L + +D Y C +NN E S ++L V IP F ++D + K+
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNN-VGEISVSTRLTVLREDQIPRGFP-TIDMGPQLKV- 136
Query: 229 ICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPL 267
VE T T + C A G+P P WFK+ LP+
Sbjct: 137 --VERT-------RTATMLCAASGNPDPEITWFKDFLPV 166
>gi|31377639 sialic acid binding Ig-like lectin 10 [Homo sapiens]
Length = 697
Score = 57.0 bits (136), Expect = 7e-08
Identities = 43/167 (25%), Positives = 68/167 (40%), Gaps = 9/167 (5%)
Query: 141 GQFVKLCCRATGHPFVQYQWFKMNKEIPNGNT-----SELIFNAVHVKDAGFYVCRVNNN 195
GQF++L C A P W N+ + + + L V D+G Y CR N
Sbjct: 269 GQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLGLELPGVKAGDSGRYTCRAENR 328
Query: 196 FTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPI 255
+ + L V PE+ + V + + L+ TS ++ G +L L CV SP
Sbjct: 329 LGSQ-QRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPP 387
Query: 256 PHYQWFKNELPLTHETKK---LYMVPYVDLEHQGTYWCHVYNDRDSQ 299
W + L+ + +P V +EH+G + CH + SQ
Sbjct: 388 ARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQ 434
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 56.2 bits (134), Expect = 1e-07
Identities = 57/242 (23%), Positives = 92/242 (38%), Gaps = 36/242 (14%)
Query: 85 EGSPSLCLLKL-MGEKGCTVTELSDFLQAMEHTEVLQLLSPPGIKITVNPESKAVLAGQF 143
EG+ SL ++++ M + G ++ + + + + L + PP P SK VL G
Sbjct: 4165 EGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSF--VTKPGSKDVLPGSA 4222
Query: 144 VKLCCRATGHPFVQYQWFKMNKEIPNGNT---------SELIFNAVHVKDAGFYVCRVNN 194
V L G + +WFK NKE+ +G + S L V D+G Y C+V+N
Sbjct: 4223 VCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSN 4282
Query: 195 NFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSP 254
+ S P +F ++ SQ L G L C G+P
Sbjct: 4283 --VAGGVECSANLFVKEPATFVEKLE-------------PSQLLKKGDATQLACKVTGTP 4327
Query: 255 IPHYQWFKNELPLTHETK---------KLYMVPYVDLEHQGTYWCHVYNDRDSQDSKKVE 305
WF N+ + +K + + V +E G Y C N+ S +
Sbjct: 4328 PIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIV 4387
Query: 306 II 307
I+
Sbjct: 4388 IV 4389
Score = 55.8 bits (133), Expect = 2e-07
Identities = 48/189 (25%), Positives = 78/189 (41%), Gaps = 26/189 (13%)
Query: 93 LKLMGEKGCTVTELSDFLQAMEHTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATG 152
L + + G V S+ + + + + PP V+P S +L G+ +L C+ G
Sbjct: 3705 LAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDP-SYLMLPGESARLHCKLKG 3763
Query: 153 HPFVQYQWFKMNKEIPNGNTSELIF---------NAVHVKDAGFYVCRVNNNFTFEFSQW 203
P +Q WFK NKE+ NT + F V V+D+G Y C N+ +
Sbjct: 3764 SPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSD--SC 3821
Query: 204 SQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKN 263
S V P SF ++ +EP ++ G+ +LQC G+ WFK+
Sbjct: 3822 STEIVIKEPPSFIKT------------LEPAD--IVRGTNALLQCEVSGTGPFEISWFKD 3867
Query: 264 ELPLTHETK 272
+ + K
Sbjct: 3868 KKQIRSSKK 3876
Score = 55.5 bits (132), Expect = 2e-07
Identities = 50/183 (27%), Positives = 76/183 (41%), Gaps = 35/183 (19%)
Query: 131 VNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEI-PNGN-TSELIFNAVHVK----- 183
+ P S V+AG+ C TG ++ W K NKEI P GN T + N H++
Sbjct: 6275 IKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVG 6334
Query: 184 --DAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPG 241
D+G Y C+ N+ + +QL V + P F + ++ +K G
Sbjct: 6335 KGDSGQYTCQATNDVGKDMCS-AQLSVKE-PPKFVKKLEASKVAK-------------QG 6379
Query: 242 STLVLQCVAVGSPIPHYQWFKNELPLTHETKK----------LYMVPYVDLEHQGTYWCH 291
++ L+C GSP WF+N+ L HE+ K L + E G Y C
Sbjct: 6380 ESIQLECKISGSPEIKVSWFRNDSEL-HESWKYNMSFINSVALLTINEASAEDSGDYICE 6438
Query: 292 VYN 294
+N
Sbjct: 6439 AHN 6441
Score = 53.1 bits (126), Expect = 1e-06
Identities = 52/214 (24%), Positives = 82/214 (38%), Gaps = 37/214 (17%)
Query: 115 HTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSE 174
+ VL PP + K + G + + C+ +G + QWFK KEI
Sbjct: 5227 YLRVLDQNIPPSFTKKLTKMDKVL--GSSIHMECKVSGSLPISAQWFKDGKEISTSAKYR 5284
Query: 175 LI---------FNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSES 225
L+ N + ++D Y C+V+N S + P SF
Sbjct: 5285 LVCHERSVSLEVNNLELEDTANYTCKVSN--VAGDDACSGILTVKEPPSF---------- 5332
Query: 226 KLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETK---------KLYM 276
V+P Q+ +P ST+ + + G+P +WFK+++ L K
Sbjct: 5333 ----LVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLN 5388
Query: 277 VPYVDLEHQGTYWCHVYNDRDSQDSKKVEIIIDE 310
+ VD G Y CHV ND S DS +++ E
Sbjct: 5389 LYSVDASKTGQYTCHVTNDVGS-DSCTTMLLVTE 5421
Score = 52.0 bits (123), Expect = 2e-06
Identities = 45/192 (23%), Positives = 83/192 (43%), Gaps = 21/192 (10%)
Query: 138 VLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGN---------TSELIFNAVHVKDAGFY 188
V G++V+L C G ++ QW K +EI + T+ L V D+G Y
Sbjct: 8357 VSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDY 8416
Query: 189 VCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQC 248
VC+ +N + ++ S++ + D P + + +L EP S +++ +T
Sbjct: 8417 VCKASNVAGSDTTK-SKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIA 8475
Query: 249 VAVGSPIPHYQWFKNELPLTHETKKLYMVPYVD---LE-------HQGTYWCHVYNDRDS 298
G PIP+ +W K + ++ ++++ D LE G Y C +N+
Sbjct: 8476 KVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGE 8535
Query: 299 QDSKKVEIIIDE 310
+S V + +DE
Sbjct: 8536 IES-NVNLQVDE 8546
Score = 51.6 bits (122), Expect = 3e-06
Identities = 43/196 (21%), Positives = 73/196 (37%), Gaps = 35/196 (17%)
Query: 118 VLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIP--------- 168
++ L PP + P AV G V L C+ G P + W+K + ++
Sbjct: 6072 LVSTLEPPYFVTELEPLEAAV--GDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYF 6129
Query: 169 NGNTSELIFNAVHVKDAGFYVCRVNNNF-TFEFSQWSQLDVCDIPESFQRSVDGVSESKL 227
N + L+FN V++ D+G Y C+ N+ T ++ +P SF R + + ++
Sbjct: 6130 TNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQT-- 6187
Query: 228 QICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETK---------KLYMVP 278
G + L C GS W+++ + L + +
Sbjct: 6188 ------------VGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKIL 6235
Query: 279 YVDLEHQGTYWCHVYN 294
DL H G Y C N
Sbjct: 6236 QTDLSHSGQYSCSASN 6251
Score = 50.8 bits (120), Expect = 5e-06
Identities = 41/158 (25%), Positives = 65/158 (41%), Gaps = 28/158 (17%)
Query: 121 LLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIP---------NGN 171
+L PP + P +V G L C+ G P + W+K + ++ N
Sbjct: 7957 ILEPPYFVKQLEPVKVSV--GDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNN 8014
Query: 172 TSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCD--IPESFQRSVDGVSESKLQI 229
+ L+FN V + D+G Y+C+ N+ E S + L V + +P SF R + V E+
Sbjct: 8015 VATLVFNQVDINDSGEYICKAENS-VGEVSASTFLTVQEQKLPPSFSRQLRDVQET---- 8069
Query: 230 CVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPL 267
G +V C GS W+K+ PL
Sbjct: 8070 ----------VGLPVVFDCAISGSEPISVSWYKDGKPL 8097
Score = 49.7 bits (117), Expect = 1e-05
Identities = 52/251 (20%), Positives = 91/251 (36%), Gaps = 39/251 (15%)
Query: 83 EPEGSPSLCLLKLMGEKGCTVTELSDFLQAMEHTEV-----LQLLSPPGIKITVNPESKA 137
E EG+ + +G+ T + +++ H + +++ + P IK + P A
Sbjct: 3409 EDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVA 3468
Query: 138 VLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGN---------TSELIFNAVHVKDAGFY 188
+ G K C P V++QWFK +EI + S L V D G Y
Sbjct: 3469 L--GHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEY 3526
Query: 189 VCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQC 248
C+ +N E+ S + E++ + P S G C
Sbjct: 3527 TCKASN----EYGSVSCTATLTVTEAYPPT----------FLSRPKSLTTFVGKAAKFIC 3572
Query: 249 VAVGSPIPHYQWFKNELPLT---------HETKKLYMVPYVDLEHQGTYWCHVYNDRDSQ 299
G+P+ W K+ L+ E K + + + ++ +G Y C N +
Sbjct: 3573 TVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGAD 3632
Query: 300 DSKKVEIIIDE 310
+ IIID+
Sbjct: 3633 ICQAELIIIDK 3643
Score = 47.4 bits (111), Expect = 5e-05
Identities = 55/203 (27%), Positives = 77/203 (37%), Gaps = 39/203 (19%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSEL-IF 177
L +L P I PES V G L C G P + +WFK KE+ + N ++ F
Sbjct: 7580 LSVLEPA--TIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFF 7637
Query: 178 NAVH--------VKDAGFYVCRVNNNFTFEFSQWSQLDVCD--IPESFQRSVDGVSESKL 227
N V D+G Y V N + S + L V D +P SF R + +
Sbjct: 7638 NKVSGLKIINVAPSDSGVYSFEVQNPVGKD-SCTASLQVSDRTVPPSFTRKLKETNG--- 7693
Query: 228 QICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWF----------KNELPLTHETKKLYMV 277
+ GS++V++C GSP WF K + LT T L V
Sbjct: 7694 -----------LSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCAL-TV 7741
Query: 278 PYVDLEHQGTYWCHVYNDRDSQD 300
++ G Y C N S +
Sbjct: 7742 NMLEESDSGDYTCIATNMAGSDE 7764
Score = 47.0 bits (110), Expect = 7e-05
Identities = 43/202 (21%), Positives = 76/202 (37%), Gaps = 48/202 (23%)
Query: 124 PPGIKITVNP-------ESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELI 176
P ++I V P ++ V+ G+ V L C +G+P W++ + +I + ++
Sbjct: 933 PAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQIT 992
Query: 177 FNA---------VHVKDAGFYVCRVNNN---------FTFEFSQWSQLDVCDIPESFQRS 218
F + +D+G + C N + S+ + + + E F
Sbjct: 993 FQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTE 1052
Query: 219 VDGVSESKLQICVE---------------------PTSQKLMPGSTLVLQCVAVGSPIPH 257
ES+ + + P QKL+ G ++V C G+P PH
Sbjct: 1053 EKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPH 1112
Query: 258 YQWFKNELPLTHETKKLYMVPY 279
W K+ +PLT T Y V Y
Sbjct: 1113 VYWKKSGVPLT--TGYRYKVSY 1132
Score = 45.4 bits (106), Expect = 2e-04
Identities = 52/230 (22%), Positives = 90/230 (39%), Gaps = 36/230 (15%)
Query: 85 EGSPSLCLLKL-MGEKGCTVTELSDFLQAMEHTEVLQLLSPPGIKITVNPESKAVLAGQF 143
E + +L +LK+ G+ G S+ + L + PP + P S+ V +F
Sbjct: 7264 ENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPPRFIKKLEP-SRIVKQDEF 7322
Query: 144 VKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIF---------NAVHVKDAGFYVCRVNN 194
+ C+ G P ++ W+K EI + + F + + V+D+G Y C +
Sbjct: 7323 TRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEA-H 7381
Query: 195 NFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSP 254
N S + L V + P F++ +P + + G+ + L+C G+P
Sbjct: 7382 NAAGSASSSTSLKVKE-PPIFRK--------------KPHPIETLKGADVHLECELQGTP 7426
Query: 255 IPHYQWFKNELPLTHETKKLYM---------VPYVDLEHQGTYWCHVYND 295
H W+K++ L K M + VD G Y C ND
Sbjct: 7427 PFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATND 7476
Score = 45.1 bits (105), Expect = 3e-04
Identities = 49/206 (23%), Positives = 77/206 (37%), Gaps = 42/206 (20%)
Query: 118 VLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIP--------- 168
VL L+ PP T + + G F+ L C G + QWFK ++EI
Sbjct: 4668 VLDLIIPPSF--TKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSF 4725
Query: 169 NGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQ 228
+ NT+ L + + D+G Y C N L V + P ++
Sbjct: 4726 HDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCS-GHLTVKEPPYFVEK----------- 4773
Query: 229 ICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPL------------THETKKLYM 276
P SQ + P + + L+ + G+ +WFK+ L T + +L+
Sbjct: 4774 ----PQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFA 4829
Query: 277 VPYVDLEHQGTYWCHVYNDRDSQDSK 302
D GTY C + ND + SK
Sbjct: 4830 AKATD---SGTYICQLSNDVGTATSK 4852
Score = 45.1 bits (105), Expect = 3e-04
Identities = 60/250 (24%), Positives = 93/250 (37%), Gaps = 55/250 (22%)
Query: 67 LRLSCLDLEQCSLKVLEPEGSPSLCLLKLMGEKGCTVTELSDFLQAMEHTEVLQLLSPPG 126
L++ C ++ L E + S +G+ CTV+ V + PP
Sbjct: 6702 LKIPCAEMSDKGLYSFEVKNS--------VGKSNCTVS-----------VHVSDRIVPPS 6742
Query: 127 IKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNG---------NTSELIF 177
I + A+L G V L CR +G + WF+ EI +G N L
Sbjct: 6743 F-IRKLKDVNAIL-GASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNL 6800
Query: 178 NAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQK 237
+ + D G Y C N + S + P SF+++ D V +
Sbjct: 6801 SLLEPSDTGIYTCVAAN--VAGSDECSAVLTVQEPPSFEQTPDSV--------------E 6844
Query: 238 LMPGSTLVLQCVAVGSPIPHYQWFKNELPLT-HETKKLYMVPYV-DLE-------HQGTY 288
++PG +L V G+P +WFK L E+ + + +V +LE G Y
Sbjct: 6845 VLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDY 6904
Query: 289 WCHVYNDRDS 298
C V ND S
Sbjct: 6905 SCLVTNDAGS 6914
Score = 45.1 bits (105), Expect = 3e-04
Identities = 38/148 (25%), Positives = 60/148 (40%), Gaps = 30/148 (20%)
Query: 137 AVLAGQFVKLCCRATGHPFVQYQWFKMNKEIP----------NGNTSELIFNAVHVKDAG 186
+ + G+ V+L G + WFK EI + N + L F+ V +AG
Sbjct: 7502 STVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAG 7561
Query: 187 FYVCRVNNNFTFE--FSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTL 244
Y C++ N+ + F+ S L+ I E +P S K+ G T
Sbjct: 7562 KYTCQIKNDAGMQECFATLSVLEPATIVE------------------KPESIKVTTGDTC 7603
Query: 245 VLQCVAVGSPIPHYQWFKNELPLTHETK 272
L+C G+P +WFK+ LT + K
Sbjct: 7604 TLECTVAGTPELSTKWFKDGKELTSDNK 7631
Score = 44.7 bits (104), Expect = 4e-04
Identities = 54/224 (24%), Positives = 88/224 (39%), Gaps = 36/224 (16%)
Query: 95 LMGEKGCTVTELSDFLQAMEHTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHP 154
L G+ CT T + + + +PP I + P V G+ C TG
Sbjct: 8123 LAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVV--GESADFECHVTGTQ 8180
Query: 155 FVQYQWFKMNKEIPNGNTSELIF--NAVHVK-------DAGFYVCRVNNNFTFEFSQWSQ 205
++ W K ++EI +G ++ + N+ H+ D+G Y C N + S +Q
Sbjct: 8181 PIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKD-SCTAQ 8239
Query: 206 LDVCD--IPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKN 263
L++ + IP SF + +L VE T G++ L+ GS W+KN
Sbjct: 8240 LNIKERLIPPSFTK--------RLSETVEETE-----GNSFKLEGRVAGSQPITVAWYKN 8286
Query: 264 EL--------PLTHETKKLYM-VPYVDLEHQGTYWCHVYNDRDS 298
+ +T + L + V + G Y C V ND S
Sbjct: 8287 NIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGS 8330
Score = 44.3 bits (103), Expect = 5e-04
Identities = 60/296 (20%), Positives = 107/296 (36%), Gaps = 54/296 (18%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGN----TSE 174
L + +PP T P L G V L C +G P + W K K++ N TS+
Sbjct: 6452 LTVKAPP--VFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSK 6509
Query: 175 LIFNAVHV-----KDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQI 229
++H+ D G Y C+ N D C F+ V
Sbjct: 6510 HFDTSLHILNLEASDVGEYHCKATNEVGS--------DTCSCSVKFKEPPRFV------- 6554
Query: 230 CVEPTSQKLMPGSTLVLQCVAVGSPIPHYQ-----WFKNELPLTHETKKLYMVPYVD--- 281
+KL STL+ V + + + +Q W K+ + E++ + ++D
Sbjct: 6555 ------KKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENT-RISFIDNIA 6607
Query: 282 --------LEHQGTYWCHVYNDRDSQDSKKVEIIIDELNNLGHPDNKEQTTDQPLAKDKV 333
+ G Y C + ND ++ V +++ + P+ TT P A + V
Sbjct: 6608 TLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFALECV 6667
Query: 334 ALLIGNMN---YREHPKLKAPLVDVYELTNLLRQLDFKVVSLLD--LTEYEMRNAV 384
++ +++ +L A N + L + D L +E++N+V
Sbjct: 6668 VTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSV 6723
Score = 43.5 bits (101), Expect = 8e-04
Identities = 64/266 (24%), Positives = 98/266 (36%), Gaps = 47/266 (17%)
Query: 63 SRGRLRLSCLDLEQCSLKVLEPEGSPSLCLLKLMGEKGCTVTELSDFLQAMEHTEVLQLL 122
S GR + L C+L V E S S G+ C T ++ + E + L +
Sbjct: 7723 SSGRKYQTTLTDNTCALTVNMLEESDS-------GDYTCIATNMAG---SDECSAPLTVR 7772
Query: 123 SPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNG---------NTS 173
PP P+ VL G V G P WFK + E+ G + +
Sbjct: 7773 EPPSF--VQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVA 7830
Query: 174 ELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEP 233
EL V +G Y C V+N + S + L + P F + ++ S K
Sbjct: 7831 ELELFDVDTSQSGEYTCIVSNE-AGKASCTTHLYI-KAPAKFVKRLNDYSIEK------- 7881
Query: 234 TSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPL---------THETKKLYMVPYVDLEH 284
G L+L+ G+P W KN + + T E + +P +E
Sbjct: 7882 -------GKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVED 7934
Query: 285 QGTYWCHVYNDRDSQDSKKVEIIIDE 310
G Y C++ N +DS +I+I E
Sbjct: 7935 AGQYNCYIEN-ASGKDSCSAQILILE 7959
Score = 43.1 bits (100), Expect = 0.001
Identities = 50/230 (21%), Positives = 85/230 (36%), Gaps = 41/230 (17%)
Query: 114 EHTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTS 173
E+ L +L P I P + V G+ L C+ G P + +W+K K + +
Sbjct: 5693 ENMATLMVLEPAVIVEKAGPMT--VTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKH 5750
Query: 174 ELIFN---------AVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCD--IPESFQRSVDGV 222
+ F +V +DAG Y +V NN + S + +DV D +P SF R +
Sbjct: 5751 KFSFYNKISSLRILSVERQDAGTYTFQVQNNVG-KSSCTAVVDVSDRAVPPSFTRRLKNT 5809
Query: 223 SESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPY--- 279
+ G++ +L+C GS WF + + K Y +
Sbjct: 5810 GG--------------VLGASCILECKVAGSSPISVAWFHEKTKIVSGAK--YQTTFSDN 5853
Query: 280 --------VDLEHQGTYWCHVYNDRDSQDSKKVEIIIDELNNLGHPDNKE 321
+D G Y C N S + + V + + + + P+ E
Sbjct: 5854 VCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLE 5903
Score = 42.4 bits (98), Expect = 0.002
Identities = 67/320 (20%), Positives = 122/320 (38%), Gaps = 43/320 (13%)
Query: 87 SPSLCLLKLM----GEKGCTVTELSDFLQAMEHTEVLQLLSPPGIKITVNPESKAVLAGQ 142
S ++C L L + G ++ + E + VL + PP + T P+S VL G
Sbjct: 6792 SENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQT--PDSVEVLPGM 6849
Query: 143 FVKLCCRATGHPFVQYQWFKMNKEIPNGNT---------SELIFNAVHVKDAGFYVCRVN 193
+ G P + +WFK ++E+ G + +EL V ++G Y C V
Sbjct: 6850 SLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVT 6909
Query: 194 NNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGS 253
N+ S + L V + +R D E+ GS +VL+ G+
Sbjct: 6910 ND-AGSASCTTHLFVKEPATFVKRLADFSVET---------------GSPIVLEATYTGT 6953
Query: 254 PIPHYQWFKNELPLTHE-------TKKLYMVPYVD--LEHQGTYWCHVYNDRDSQDSKKV 304
P W K+E ++ T+K ++ ++ +E Y C + N+ + +
Sbjct: 6954 PPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEAL 7013
Query: 305 EIIIDELNNLGHPDNKEQTTDQPL---AKDKVALLIGNMNYREHPKLKAPLVDVYELTNL 361
+++ + ++ E +P K I Y+EH KL++ + N
Sbjct: 7014 VSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNN 7073
Query: 362 LRQLDFKVVSLLDLTEYEMR 381
+ L V D+ EY +
Sbjct: 7074 VASLVINKVDHSDVGEYSCK 7093
Score = 41.6 bits (96), Expect = 0.003
Identities = 50/213 (23%), Positives = 81/213 (38%), Gaps = 40/213 (18%)
Query: 118 VLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNG------- 170
+L + PP V P + + V+ G P + +WFK + E+ +G
Sbjct: 5323 ILTVKEPPSF--LVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGL 5380
Query: 171 --NTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQ 228
+TS L +V G Y C V N+ + S + L V + P F + ++
Sbjct: 5381 EGSTSFLNLYSVDASKTGQYTCHVTNDVGSD-SCTTMLLVTE-PPKFVKKLEA------- 5431
Query: 229 ICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVD------- 281
S+ + G + L+C GSP WF+NE L K Y + ++D
Sbjct: 5432 ------SKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDK--YRMTFIDSVAVIQM 5483
Query: 282 ----LEHQGTYWCHVYNDRDSQDSKKVEIIIDE 310
E G + C N S S ++I+ E
Sbjct: 5484 NNLSTEDSGDFICEAQNPAGS-TSCSTKVIVKE 5515
Score = 41.2 bits (95), Expect = 0.004
Identities = 47/191 (24%), Positives = 73/191 (38%), Gaps = 37/191 (19%)
Query: 131 VNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNG---------NTSELIFNAVH 181
+ P S + G+ C TG ++ W K N+EI G NT+ L V
Sbjct: 7216 LKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVG 7275
Query: 182 VKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPG 241
DAG Y C +N + S +QL V + P ++ +EP S+ +
Sbjct: 7276 KGDAGQYTCYA-SNIAGKDSCSAQLGVQEPPRFIKK-------------LEP-SRIVKQD 7320
Query: 242 STLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVD-----------LEHQGTYWC 290
+C GSP W+K+E + +K + + +VD +E G Y C
Sbjct: 7321 EFTRYECKIGGSPEIKVLWYKDETEIQESSK--FRMSFVDSVAVLEMHNLSVEDSGDYTC 7378
Query: 291 HVYNDRDSQDS 301
+N S S
Sbjct: 7379 EAHNAAGSASS 7389
Score = 40.4 bits (93), Expect = 0.007
Identities = 45/225 (20%), Positives = 82/225 (36%), Gaps = 37/225 (16%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNT----SE 174
L++ PP + P L G V L C G P W+K +E+ +G SE
Sbjct: 7393 LKVKEPPIFR--KKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSE 7450
Query: 175 LIFNAVHV-----KDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQI 229
++H+ D G Y C+ N+ + S P F + + +S
Sbjct: 7451 NFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSI--ALKAPPRFVKKLSDIST----- 7503
Query: 230 CVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYM----------VPY 279
+ G + LQ G+ WFK++ + E+ +++
Sbjct: 7504 ---------VVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSR 7554
Query: 280 VDLEHQGTYWCHVYNDRDSQDSKKVEIIIDELNNLGHPDNKEQTT 324
V+ + G Y C + ND Q+ +++ + P++ + TT
Sbjct: 7555 VEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTT 7599
Score = 39.3 bits (90), Expect = 0.015
Identities = 49/207 (23%), Positives = 82/207 (39%), Gaps = 39/207 (18%)
Query: 68 RLSCLDLEQCSLKVLEPEGSPSLCLLKLMGEKGCTVTELSDFLQAMEHTEVLQLLSPPGI 127
R+S +D +L++ PE S S G + ++ + E + VL +L P
Sbjct: 6599 RISFID-NIATLQLGSPEASNS----------GKYICQIKNDAGMRECSAVLTVLEPA-- 6645
Query: 128 KITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIF---------N 178
+I PE V G L C TG P + +WFK +E+ + + F
Sbjct: 6646 RIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIP 6705
Query: 179 AVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCD--IPESFQRSVDGVSESKLQICVEPTSQ 236
+ D G Y V N+ + + + V D +P SF R + V+
Sbjct: 6706 CAEMSDKGLYSFEVKNS-VGKSNCTVSVHVSDRIVPPSFIRKLKDVN------------- 6751
Query: 237 KLMPGSTLVLQCVAVGSPIPHYQWFKN 263
+ G+++VL+C GS WF++
Sbjct: 6752 -AILGASVVLECRVSGSAPISVGWFQD 6777
Score = 39.3 bits (90), Expect = 0.015
Identities = 44/214 (20%), Positives = 78/214 (36%), Gaps = 40/214 (18%)
Query: 118 VLQLLSPPGIKITVNP-ESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNG------ 170
++ +L PP + P E + G+ L C+ G P ++ W+K + ++ +
Sbjct: 7013 LVSVLEPPYF---IEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQ 7069
Query: 171 ---NTSELIFNAVHVKDAGFYVCRVNNNF-TFEFSQWSQLDVCDIPESFQRSVDGVSESK 226
N + L+ N V D G Y C+ +N+ S + +P F R + V E+
Sbjct: 7070 FKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETL 7129
Query: 227 LQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKN----------ELPLTHETKKLYM 276
G + +C GS W+K+ + H L +
Sbjct: 7130 --------------GFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQI 7175
Query: 277 VPYVDLEHQGTYWCHVYNDRDSQDSKKVEIIIDE 310
+ D H G Y C N + S ++I+ E
Sbjct: 7176 L-QTDQSHIGQYNCSASNPLGTA-SSSAKLILSE 7207
Score = 39.3 bits (90), Expect = 0.015
Identities = 33/142 (23%), Positives = 50/142 (35%), Gaps = 40/142 (28%)
Query: 141 GQFVKLCCRATGHPFVQYQWFKMNKEI---------PNGNTSELIFNAVHVKDAGFYVCR 191
G+ +L C+ G P +W++ KE+ +G T L +D G Y C
Sbjct: 30547 GEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCI 30606
Query: 192 VNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMP---------GS 242
N +V ++ S SKL + P P GS
Sbjct: 30607 ATN------------EVGEVETS----------SKLLLQATPQFHPGYPLKEKYYGAVGS 30644
Query: 243 TLVLQCVAVGSPIPHYQWFKNE 264
TL L + +G P+P WF +
Sbjct: 30645 TLRLHVMYIGRPVPAMTWFHGQ 30666
Score = 38.9 bits (89), Expect = 0.019
Identities = 41/184 (22%), Positives = 69/184 (37%), Gaps = 34/184 (18%)
Query: 133 PESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEI---PNGNTSE------LIFNAVHVK 183
P+S G+ K C TG P ++ W K + PN S+ L + + ++
Sbjct: 3557 PKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQ 3616
Query: 184 DAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGST 243
D G Y C+ +N F + Q ++L + D P + +EP +
Sbjct: 3617 DRGVYSCKASNKFGADICQ-AELIIIDKPHFIKE-------------LEPVQSAI--NKK 3660
Query: 244 LVLQCVAVGSPIPHYQWFKN--ELPLTHETKKLYM-------VPYVDLEHQGTYWCHVYN 294
+ L+C W K+ +LP + K + +P L+ GTY C N
Sbjct: 3661 VHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASN 3720
Query: 295 DRDS 298
+ S
Sbjct: 3721 EAGS 3724
Score = 38.9 bits (89), Expect = 0.019
Identities = 23/88 (26%), Positives = 39/88 (44%), Gaps = 10/88 (11%)
Query: 116 TEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSEL 175
T +L + PP + SK V AG +L C+ G P ++ WF+ E+P + +
Sbjct: 5414 TTMLLVTEPPKF-VKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRM 5472
Query: 176 IF---------NAVHVKDAGFYVCRVNN 194
F N + +D+G ++C N
Sbjct: 5473 TFIDSVAVIQMNNLSTEDSGDFICEAQN 5500
Score = 38.5 bits (88), Expect = 0.025
Identities = 14/37 (37%), Positives = 21/37 (56%)
Query: 232 EPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLT 268
+P SQ + G ++ C G P P +WFKN LP++
Sbjct: 33139 QPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPIS 33175
Score = 37.7 bits (86), Expect = 0.043
Identities = 41/189 (21%), Positives = 76/189 (40%), Gaps = 39/189 (20%)
Query: 116 TEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEI-PNGNTSE 174
T+ ++LL P + T+ +K G+ V+ T HP W+K ++I P N +
Sbjct: 31680 TDTMRLLERPP-EFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKK 31738
Query: 175 LIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICV--- 231
F + D G Y +N+ T + ++++ + R+ G K ++ V
Sbjct: 31739 YTFES----DKGLYQLTINSVTTDDDAEYTVV---------ARNKYGEDSCKAKLTVTLH 31785
Query: 232 -EPTSQKLMP-------------GSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMV 277
PT L P G ++ + G P P +W K+ PL+ +
Sbjct: 31786 PPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLS-------LG 31838
Query: 278 PYVDLEHQG 286
P +++ H+G
Sbjct: 31839 PNIEIIHEG 31847
Score = 37.4 bits (85), Expect = 0.056
Identities = 49/232 (21%), Positives = 84/232 (36%), Gaps = 37/232 (15%)
Query: 111 QAMEHTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIP-- 168
+A T V +L+ KI E V AG L G P ++ +W+K + +
Sbjct: 4001 EAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVAS 4060
Query: 169 -------NGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQ--WSQLDVCDIPESFQRSV 219
N ++L F + + D+G Y ++N + ++ LD DI F + +
Sbjct: 4061 KKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDR-DIAPFFTKPL 4119
Query: 220 DGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKN----------ELPLTH 269
V + T L C GS WFK+ +
Sbjct: 4120 RNVDS--------------VVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVE 4165
Query: 270 ETKKLYMVPYVDLEHQGTYWCHVYNDRDSQDSKKVEIIIDELNNLGHPDNKE 321
T L ++ VD+ G + C N S+DS I+ + + + P +K+
Sbjct: 4166 GTASLEIIR-VDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKD 4216
Score = 37.0 bits (84), Expect = 0.073
Identities = 48/204 (23%), Positives = 77/204 (37%), Gaps = 53/204 (25%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNG-------- 170
++L PP +N S V+AG+ +L G + QW K +E+
Sbjct: 5604 VKLKEPPRFVSKLN--SLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITF 5661
Query: 171 --NTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQ 228
N + L F +AG Y+C++ N+ G+ E+
Sbjct: 5662 VENVATLQFAKAEPANAGKYICQIKND------------------------GGMRENMAT 5697
Query: 229 ICV-EPTS--QKLMP-----GSTLVLQCVAVGSPIPHYQWFKNELPLTHETK-------K 273
+ V EP +K P G T L+C G+P +W+K+ LT K K
Sbjct: 5698 LMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNK 5757
Query: 274 LYMVPYVDLEHQ--GTYWCHVYND 295
+ + + +E Q GTY V N+
Sbjct: 5758 ISSLRILSVERQDAGTYTFQVQNN 5781
Score = 36.6 bits (83), Expect = 0.096
Identities = 44/202 (21%), Positives = 78/202 (38%), Gaps = 37/202 (18%)
Query: 87 SPSLCLLKL-------MGEKGCTVTELSDFLQAMEHTEVLQLLSPPGIKITVNPESKAVL 139
S ++C L+L MG C ++ + E VL + PP PE VL
Sbjct: 5851 SDNVCTLQLNSLDSSDMGNYTCVAANVAG---SDECRAVLTVQEPPSF--VKEPEPLEVL 5905
Query: 140 AGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFN---------AVHVKDAGFYVC 190
G+ V G P + WF+ +E+ G+ + F + + +G Y C
Sbjct: 5906 PGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTC 5965
Query: 191 RVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVA 250
V+NN + S ++L V + P +F + + + + PG +++L+
Sbjct: 5966 VVSNN-AGQASCTTRLFVKE-PAAFLKRL--------------SDHSVEPGKSIILESTY 6009
Query: 251 VGSPIPHYQWFKNELPLTHETK 272
G+ W K+ +T K
Sbjct: 6010 TGTLPISVTWKKDGFNITTSEK 6031
Score = 35.8 bits (81), Expect = 0.16
Identities = 48/213 (22%), Positives = 76/213 (35%), Gaps = 38/213 (17%)
Query: 116 TEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSEL 175
TE++ + PP T+ P ++ G L C +G + WFK K+I + L
Sbjct: 3823 TEIV-IKEPPSFIKTLEPAD--IVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRL 3879
Query: 176 IFN---------AVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESK 226
+ + D G Y C V N + L P +F + VD +
Sbjct: 3880 FSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHL--LKEPPTFVKKVDDLIA-- 3935
Query: 227 LQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETK---------KLYMV 277
+ G T+ LQ GS W K + + + K + ++
Sbjct: 3936 ------------LGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLII 3983
Query: 278 PYVDLEHQGTYWCHVYNDRDSQDSKKVEIIIDE 310
P V + G Y C N+ SQ S E+I+ E
Sbjct: 3984 PDVQISFGGKYTCLAENEAGSQTSVG-ELIVKE 4015
Score = 35.8 bits (81), Expect = 0.16
Identities = 44/172 (25%), Positives = 63/172 (36%), Gaps = 38/172 (22%)
Query: 144 VKLCCRATGHPFVQYQWFKMNKEIPNGNTSEL-----IFNAVHV-----KDAGFYVCRVN 193
V+L C TG P + W K N+EI + L +FN +H+ D G Y C V+
Sbjct: 4972 VELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFN-LHITKCDPSDTGEYQCIVS 5030
Query: 194 NNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGS 253
N S P SF + +E T+ L +T Q GS
Sbjct: 5031 NE--GGSCSCSTRVALKEPPSFIKK------------IENTTTVLKSSAT--FQSTVAGS 5074
Query: 254 PIPHYQWFKNELPLTHETKKLYM----------VPYVDLEHQGTYWCHVYND 295
P W K++ + E +Y+ + VD H G Y C N+
Sbjct: 5075 PPISITWLKDD-QILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNE 5125
Score = 35.8 bits (81), Expect = 0.16
Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 11/85 (12%)
Query: 139 LAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGN----------TSELIFNAVHVKDAGFY 188
L G+ V + +G P W K I N TS + N V KDAGFY
Sbjct: 31040 LRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFY 31099
Query: 189 VCRVNNNFTFEFSQWSQLDVCDIPE 213
V N F + + +LDV D+P+
Sbjct: 31100 VVCAKNRFGID-QKTVELDVADVPD 31123
Score = 35.4 bits (80), Expect = 0.21
Identities = 37/173 (21%), Positives = 68/173 (39%), Gaps = 22/173 (12%)
Query: 113 MEHTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNT 172
+E T+ QL + P S L GQ + + G P + WF ++I N T
Sbjct: 1443 LEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYT 1502
Query: 173 SELIFNAVHVKDAGFYVCRVNNNFTFEFSQW----------SQLDVCDIPESFQRSVDGV 222
+++ +K+ G + + +W S + V E+ + V +
Sbjct: 1503 HKVV-----IKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPM 1557
Query: 223 SESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKN-ELPLTHETKKL 274
KL+ + + GS L ++ A G+P P W KN ++ + H+ K+
Sbjct: 1558 FVEKLK------NVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKI 1604
Score = 35.4 bits (80), Expect = 0.21
Identities = 51/221 (23%), Positives = 79/221 (35%), Gaps = 39/221 (17%)
Query: 98 EKGCTVTELSDFLQAMEHTEVLQLLSPPGIKITVNPESKAVLA-GQFVKLCCRATGHPFV 156
+ G + +LS+ + L + PP + P VL GQ C+ TG P +
Sbjct: 4834 DSGTYICQLSNDVGTATSKATLFVKEPP--QFIKKPSPVLVLRNGQSTTFECQITGTPKI 4891
Query: 157 QYQWFKMNKEIPNGNTSELIF---------NAVHVKDAGFYVCRVNNNFTFEFSQWSQLD 207
+ W+ EI + F + V+++G YVC N+ S +L
Sbjct: 4892 RVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARND-AGTASCSIELK 4950
Query: 208 VCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPL 267
V + P +F R + V K S + L+C G+P W KN +
Sbjct: 4951 VKE-PPTFIRELKPVEVVKY--------------SDVELECEVTGTPPFEVTWLKNNREI 4995
Query: 268 THETKKLYMVPYV----------DLEHQGTYWCHVYNDRDS 298
+KK + V D G Y C V N+ S
Sbjct: 4996 -RSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGS 5035
Score = 35.0 bits (79), Expect = 0.28
Identities = 27/96 (28%), Positives = 38/96 (39%), Gaps = 10/96 (10%)
Query: 133 PESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIP---------NGNTSELIFNAVHVK 183
P S+ + GQ V C +G P + +WFK N I + N L V
Sbjct: 33140 PRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVS 33199
Query: 184 DAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSV 219
D+G Y + NF + S + L V + E R V
Sbjct: 33200 DSGKYTIKA-KNFRGQCSATASLMVLPLVEEPSREV 33234
Score = 34.7 bits (78), Expect = 0.36
Identities = 37/185 (20%), Positives = 67/185 (36%), Gaps = 40/185 (21%)
Query: 148 CRAT--GHPFVQYQWFKMNKEIPNGNTSELI---------FNAVHVKDAGFYVCRVNNNF 196
CR T G P + +W K + N +I + + +D+G CR N +
Sbjct: 1724 CRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKY 1783
Query: 197 TFEFS--------QWSQLDVCDIPES---FQR----------------SVDGVSESKLQI 229
+ + + S ++ +PE QR + D + K I
Sbjct: 1784 GTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDI 1843
Query: 230 CVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYW 289
+ P +++ G T +C G P P W+ N L ++K+ + V Y + +
Sbjct: 1844 VLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNG-QLIRKSKR-FRVRYDGIHYLDIVD 1901
Query: 290 CHVYN 294
C Y+
Sbjct: 1902 CKSYD 1906
Score = 34.3 bits (77), Expect = 0.48
Identities = 42/181 (23%), Positives = 58/181 (32%), Gaps = 36/181 (19%)
Query: 138 VLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAVHVK---------DAGFY 188
VL V L G P + WFK N + +G + V DAG Y
Sbjct: 4404 VLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEY 4463
Query: 189 VCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQC 248
CRV N S P SF + ++ S + G T Q
Sbjct: 4464 QCRVTNEVGSSIC--SARVTLREPPSFIKKIESTSSLR--------------GGTAAFQA 4507
Query: 249 VAVGSPIPHYQWFKNELPLTHETK----------KLYMVPYVDLEHQGTYWCHVYNDRDS 298
GS W K+ +T + LY+ ++++H G Y C ND
Sbjct: 4508 TLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSG-IEVKHDGKYVCQAKNDAGI 4566
Query: 299 Q 299
Q
Sbjct: 4567 Q 4567
Score = 33.5 bits (75), Expect = 0.81
Identities = 15/56 (26%), Positives = 26/56 (46%)
Query: 129 ITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAVHVKD 184
I + PE VL G+ + CR TG+P + W+ + I + ++ +H D
Sbjct: 1843 IVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLD 1898
Score = 33.1 bits (74), Expect = 1.1
Identities = 35/155 (22%), Positives = 60/155 (38%), Gaps = 26/155 (16%)
Query: 54 WRRLAELAGSRGRLRLSCLDLEQCSLKVLEPE----GSPSLCLLKLMGEKGCTVTELSDF 109
W + + S G+ ++S L+ L VL+ + G + + +G+ CT
Sbjct: 8186 WAKDSREIRSGGKYQISYLE-NSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTA------ 8238
Query: 110 LQAMEHTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPN 169
+ + L PP ++ E+ G KL R G + W+K N EI
Sbjct: 8239 -----QLNIKERLIPPSFTKRLS-ETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQP 8292
Query: 170 GNTSELIFN---------AVHVKDAGFYVCRVNNN 195
+ E+ F + DAG Y C+V+N+
Sbjct: 8293 TSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSND 8327
Score = 31.6 bits (70), Expect = 3.1
Identities = 31/118 (26%), Positives = 45/118 (38%), Gaps = 22/118 (18%)
Query: 91 CLLKLMGEKGCTV--TELSDFLQAMEHTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCC 148
CLL E C V S L +E V T N + V +KL C
Sbjct: 12435 CLLDDEAEYSCEVRTARTSGMLTVLEEEAVF----------TKNLANIEVSETDTIKLVC 12484
Query: 149 RATGHPFVQYQWFKMNKEI---------PNGNTSELIFNAVHVKDAGFYVCRVNNNFT 197
+ P + W+K ++EI G L+ H++DAG Y CR+ ++ T
Sbjct: 12485 EVS-KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRT 12541
Score = 31.2 bits (69), Expect = 4.0
Identities = 19/60 (31%), Positives = 25/60 (41%), Gaps = 11/60 (18%)
Query: 146 LCCRATGHPFVQYQWFKMNKEIP-----------NGNTSELIFNAVHVKDAGFYVCRVNN 194
L C+ TGHP +W++ KEI G +LI +V DA Y R N
Sbjct: 30947 LVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATN 31006
Score = 30.8 bits (68), Expect = 5.3
Identities = 33/134 (24%), Positives = 46/134 (34%), Gaps = 23/134 (17%)
Query: 85 EGSPSLCLLKLMG-------EKGCTVTELSDFLQAMEHTEVLQLLSPPGIK-------IT 130
EG S L+ MG EK ++E Q + V + P + I
Sbjct: 32796 EGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIV 32855
Query: 131 VNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSEL------IFNAVH--- 181
+ V + K +ATG P W K K I G +L F +H
Sbjct: 32856 TGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTD 32915
Query: 182 VKDAGFYVCRVNNN 195
D+G Y C V N+
Sbjct: 32916 TSDSGLYTCTVKNS 32929
Score = 30.4 bits (67), Expect = 6.9
Identities = 12/40 (30%), Positives = 21/40 (52%)
Query: 138 VLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIF 177
+L G V C+ +G+P + W+K K I +G ++ F
Sbjct: 1302 ILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDF 1341
Score = 30.4 bits (67), Expect = 6.9
Identities = 23/97 (23%), Positives = 39/97 (40%), Gaps = 20/97 (20%)
Query: 109 FLQAMEHTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMN---- 164
++ A E +VLQ L P +TV +G+ + C +G P + W+K
Sbjct: 3232 YVNAPEPPQVLQELQP----VTVQ-------SGKPARFCAVISGRPQPKISWYKEEQLLS 3280
Query: 165 -----KEIPNGNTSELIFNAVHVKDAGFYVCRVNNNF 196
K + +G L+ +DA Y C N++
Sbjct: 3281 TGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDY 3317
Score = 30.4 bits (67), Expect = 6.9
Identities = 45/177 (25%), Positives = 68/177 (38%), Gaps = 19/177 (10%)
Query: 107 SDFLQAMEHTEVLQLLSPPGIKITVN-PESKAVLAGQFVKLCCRATGHPFVQYQWFKMNK 165
SD E V L PP + + N + + G ++L G PF + W K ++
Sbjct: 17198 SDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDR 17257
Query: 166 EIPN---------GNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQ 216
+ P G+ E I NA H +D G Y V N + L V D P
Sbjct: 17258 DAPTKARIDVTPVGSKLE-IRNAAH-EDGGIYSLTVENPAGSKTVSVKVL-VLDKPGP-P 17313
Query: 217 RSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKK 273
R ++ VSE + C + L G +++ V + QW PL+ +KK
Sbjct: 17314 RDLE-VSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQW----SPLSATSKK 17365
Score = 30.4 bits (67), Expect = 6.9
Identities = 33/166 (19%), Positives = 66/166 (39%), Gaps = 16/166 (9%)
Query: 165 KEIPNGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQ-----RSV 219
+++P+G ++ F +V + F + + N +EF +++ V I + +
Sbjct: 26807 RDLPDGRWTKASFT--NVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCI 26864
Query: 220 DGVSESKLQICVEPTSQ-KLMPGSTLVLQCVAVGSPIPHYQWFK-------NELPLTHET 271
D + + +E T K G+++ L+ G P P +W+K N L T
Sbjct: 26865 DSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENT 26924
Query: 272 KKLYMVPYVDLEHQGTYWCHVYNDRDSQDSKKVEIIIDELNNLGHP 317
L + D + + C+ R++ S I + L+ G P
Sbjct: 26925 TDLASILIKDADRLNS-GCYELKLRNAMGSASATIRVQILDKPGPP 26969
Score = 30.0 bits (66), Expect = 9.0
Identities = 42/186 (22%), Positives = 74/186 (39%), Gaps = 28/186 (15%)
Query: 226 KLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYM--------- 276
KL++ V + K+ G + + G P+P +W KNE + T L +
Sbjct: 15398 KLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSE 15457
Query: 277 ------VPYVDLEHQGTYWCHVYNDRDSQDSKKVEIIIDEL----NNLGHPDNKEQ---- 322
+P E +GTY N R + V + + + NL D K +
Sbjct: 15458 AKTELSIPKAVREDKGTYTVTASN-RLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYL 15516
Query: 323 TTDQPLAKDKVALLIGNMNYREHPKLKAPLVDVYELTNLLRQLDFKVVSLLDLTEYEMR- 381
T D PL + ++ R+ + KA + E+TN + + + L+ +YE R
Sbjct: 15517 TWDAPLDNGGSEITHYVIDKRDASRKKA---EWEEVTNTAVEKRYGIWKLIPNGQYEFRV 15573
Query: 382 NAVDEF 387
AV+++
Sbjct: 15574 RAVNKY 15579
>gi|40255157 leucine-rich repeats and immunoglobulin-like domains 3
isoform 2 [Homo sapiens]
Length = 1119
Score = 55.8 bits (133), Expect = 2e-07
Identities = 49/182 (26%), Positives = 70/182 (38%), Gaps = 33/182 (18%)
Query: 130 TVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMN-KEIPNGNTSEL-------IFNAVH 181
T P + AG +L C A GHP Q W K + P + +F V
Sbjct: 606 TKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVD 665
Query: 182 VK--DAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLM 239
VK D G Y C N+ S + L V + P + +D + +
Sbjct: 666 VKIEDIGVYSCTAQNS-AGSISANATLTVLETPSFLRPLLD---------------RTVT 709
Query: 240 PGSTLVLQCVAVGSPIPHYQWFKNELPLTHETK-------KLYMVPYVDLEHQGTYWCHV 292
G T VLQC+A GSP P W K++ PL + +L ++ D+ G Y C +
Sbjct: 710 KGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEM 769
Query: 293 YN 294
N
Sbjct: 770 SN 771
Score = 47.4 bits (111), Expect = 5e-05
Identities = 51/241 (21%), Positives = 91/241 (37%), Gaps = 50/241 (20%)
Query: 125 PGIKITVNPESKAVLAGQFVKLCCRA--TGHPFVQYQWFKMNKEIPNGN----------- 171
P +ITV PE+++ + G + C A + + + W K N+ + +
Sbjct: 497 PKPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQG 556
Query: 172 ------TSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSES 225
T+ L V G Y C ++N+F +S ++L V +P SF ++
Sbjct: 557 GEVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLP-SFTKT------- 608
Query: 226 KLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKN---ELPLTHETK-------KLY 275
P + G+ L+C AVG P P W K+ + P E + ++
Sbjct: 609 -------PMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVF 661
Query: 276 MVPYVDLEHQGTYWCHVYNDRDSQDSKKVEIIIDELNNLGHPDNKEQTTDQPLAKDKVAL 335
+ V +E G Y C N S + +++ P D+ + K + A+
Sbjct: 662 FIVDVKIEDIGVYSCTAQNSAGSISANATLTVLET------PSFLRPLLDRTVTKGETAV 715
Query: 336 L 336
L
Sbjct: 716 L 716
>gi|209862903 leucine-rich repeats and immunoglobulin-like domains 3
isoform 1 [Homo sapiens]
Length = 1059
Score = 55.8 bits (133), Expect = 2e-07
Identities = 49/182 (26%), Positives = 70/182 (38%), Gaps = 33/182 (18%)
Query: 130 TVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMN-KEIPNGNTSEL-------IFNAVH 181
T P + AG +L C A GHP Q W K + P + +F V
Sbjct: 546 TKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVD 605
Query: 182 VK--DAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLM 239
VK D G Y C N+ S + L V + P + +D + +
Sbjct: 606 VKIEDIGVYSCTAQNS-AGSISANATLTVLETPSFLRPLLD---------------RTVT 649
Query: 240 PGSTLVLQCVAVGSPIPHYQWFKNELPLTHETK-------KLYMVPYVDLEHQGTYWCHV 292
G T VLQC+A GSP P W K++ PL + +L ++ D+ G Y C +
Sbjct: 650 KGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEM 709
Query: 293 YN 294
N
Sbjct: 710 SN 711
Score = 47.4 bits (111), Expect = 5e-05
Identities = 51/241 (21%), Positives = 91/241 (37%), Gaps = 50/241 (20%)
Query: 125 PGIKITVNPESKAVLAGQFVKLCCRA--TGHPFVQYQWFKMNKEIPNGN----------- 171
P +ITV PE+++ + G + C A + + + W K N+ + +
Sbjct: 437 PKPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQG 496
Query: 172 ------TSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSES 225
T+ L V G Y C ++N+F +S ++L V +P SF ++
Sbjct: 497 GEVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLP-SFTKT------- 548
Query: 226 KLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKN---ELPLTHETK-------KLY 275
P + G+ L+C AVG P P W K+ + P E + ++
Sbjct: 549 -------PMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVF 601
Query: 276 MVPYVDLEHQGTYWCHVYNDRDSQDSKKVEIIIDELNNLGHPDNKEQTTDQPLAKDKVAL 335
+ V +E G Y C N S + +++ P D+ + K + A+
Sbjct: 602 FIVDVKIEDIGVYSCTAQNSAGSISANATLTVLET------PSFLRPLLDRTVTKGETAV 655
Query: 336 L 336
L
Sbjct: 656 L 656
>gi|19743806 roundabout 1 isoform b [Homo sapiens]
Length = 1612
Score = 55.1 bits (131), Expect = 3e-07
Identities = 50/215 (23%), Positives = 80/215 (37%), Gaps = 33/215 (15%)
Query: 97 GEKGCTVTELSDFLQAMEHTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHP-- 154
G+ G + + E + L + PP V P + V G+ V C ATG+P
Sbjct: 284 GDMGSYTCVAENMVGKAEASATLTVQEPP--HFVVKPRDQVVALGRTVTFQCEATGNPQP 341
Query: 155 ------------FVQYQWFKMNKEIPNGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQ 202
YQ + + T +L V D G+Y+C+ N ++
Sbjct: 342 AIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITK 401
Query: 203 WSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFK 262
+ L+V D+ V I P +Q + T VL CVA GSP+P W K
Sbjct: 402 -AYLEVTDVIADRPPPV---------IRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRK 451
Query: 263 NELPLTHETKKL-------YMVPYVDLEHQGTYWC 290
+ + ++ + ++ + Y L G Y C
Sbjct: 452 DGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTC 486
Score = 47.8 bits (112), Expect = 4e-05
Identities = 51/228 (22%), Positives = 87/228 (38%), Gaps = 44/228 (19%)
Query: 124 PPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEI--------------PN 169
PP +I +P V G+ L C+A G P +W+K + + P+
Sbjct: 28 PP--RIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPS 85
Query: 170 GNTSELIFNAVHVK----DAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSES 225
G S VH + D G YVC N S + L+V + + F+++
Sbjct: 86 G--SLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQN------- 136
Query: 226 KLQICVEPTSQKLMPGSTLVLQCVAV-GSPIPHYQWFKNELPLTHETKKL------YMVP 278
P+ + G V++C G P P W K+ PL + +++ M+
Sbjct: 137 -------PSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMIT 189
Query: 279 YVDLEHQGTYWCHVYNDRDSQDSKKVEI-IIDELNNLGHPDNKEQTTD 325
Y G Y C N ++S+ E+ +++ + + P N T D
Sbjct: 190 YTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVD 237
Score = 40.0 bits (92), Expect = 0.009
Identities = 39/152 (25%), Positives = 54/152 (35%), Gaps = 24/152 (15%)
Query: 114 EHTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNG--- 170
E E+ L P +K P + AV + C A G P +W K + E+P
Sbjct: 213 EVAELTVLERPSFVK---RPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYE 269
Query: 171 --NTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQ 228
+ L V D G Y C V N + + L V + P
Sbjct: 270 IRDDHTLKIRKVTAGDMGSYTC-VAENMVGKAEASATLTVQEPP---------------H 313
Query: 229 ICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQW 260
V+P Q + G T+ QC A G+P P W
Sbjct: 314 FVVKPRDQVVALGRTVTFQCEATGNPQPAIFW 345
Score = 39.3 bits (90), Expect = 0.015
Identities = 44/178 (24%), Positives = 70/178 (39%), Gaps = 33/178 (18%)
Query: 132 NPESKAVLAGQFVKLCCRAT-GHPFVQYQWFKMNKEIPNGNT------SELIFNAVHVKD 184
NP V G+ + C+ GHP W K + + + +L+ D
Sbjct: 136 NPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSD 195
Query: 185 AGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTL 244
AG YVC N S+ ++L V + P +R S L + V+ +++
Sbjct: 196 AGKYVCVGTNMVGERESEVAELTVLERPSFVKRP------SNLAVTVDDSAE-------- 241
Query: 245 VLQCVAVGSPIPHYQWFKN--ELPLTH------ETKKLYMVPYVDLEHQGTYWCHVYN 294
+C A G P+P +W K+ ELP + T K+ V D+ G+Y C N
Sbjct: 242 -FKCEARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDM---GSYTCVAEN 295
>gi|4506569 roundabout 1 isoform a [Homo sapiens]
Length = 1651
Score = 55.1 bits (131), Expect = 3e-07
Identities = 50/215 (23%), Positives = 80/215 (37%), Gaps = 33/215 (15%)
Query: 97 GEKGCTVTELSDFLQAMEHTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHP-- 154
G+ G + + E + L + PP V P + V G+ V C ATG+P
Sbjct: 323 GDMGSYTCVAENMVGKAEASATLTVQEPP--HFVVKPRDQVVALGRTVTFQCEATGNPQP 380
Query: 155 ------------FVQYQWFKMNKEIPNGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQ 202
YQ + + T +L V D G+Y+C+ N ++
Sbjct: 381 AIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITK 440
Query: 203 WSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFK 262
+ L+V D+ V I P +Q + T VL CVA GSP+P W K
Sbjct: 441 -AYLEVTDVIADRPPPV---------IRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRK 490
Query: 263 NELPLTHETKKL-------YMVPYVDLEHQGTYWC 290
+ + ++ + ++ + Y L G Y C
Sbjct: 491 DGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTC 525
Score = 47.8 bits (112), Expect = 4e-05
Identities = 51/228 (22%), Positives = 87/228 (38%), Gaps = 44/228 (19%)
Query: 124 PPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEI--------------PN 169
PP +I +P V G+ L C+A G P +W+K + + P+
Sbjct: 67 PP--RIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPS 124
Query: 170 GNTSELIFNAVHVK----DAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSES 225
G S VH + D G YVC N S + L+V + + F+++
Sbjct: 125 G--SLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQN------- 175
Query: 226 KLQICVEPTSQKLMPGSTLVLQCVAV-GSPIPHYQWFKNELPLTHETKKL------YMVP 278
P+ + G V++C G P P W K+ PL + +++ M+
Sbjct: 176 -------PSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMIT 228
Query: 279 YVDLEHQGTYWCHVYNDRDSQDSKKVEI-IIDELNNLGHPDNKEQTTD 325
Y G Y C N ++S+ E+ +++ + + P N T D
Sbjct: 229 YTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVD 276
Score = 40.0 bits (92), Expect = 0.009
Identities = 39/152 (25%), Positives = 54/152 (35%), Gaps = 24/152 (15%)
Query: 114 EHTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNG--- 170
E E+ L P +K P + AV + C A G P +W K + E+P
Sbjct: 252 EVAELTVLERPSFVK---RPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYE 308
Query: 171 --NTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQ 228
+ L V D G Y C V N + + L V + P
Sbjct: 309 IRDDHTLKIRKVTAGDMGSYTC-VAENMVGKAEASATLTVQEPP---------------H 352
Query: 229 ICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQW 260
V+P Q + G T+ QC A G+P P W
Sbjct: 353 FVVKPRDQVVALGRTVTFQCEATGNPQPAIFW 384
Score = 39.3 bits (90), Expect = 0.015
Identities = 44/178 (24%), Positives = 70/178 (39%), Gaps = 33/178 (18%)
Query: 132 NPESKAVLAGQFVKLCCRAT-GHPFVQYQWFKMNKEIPNGNT------SELIFNAVHVKD 184
NP V G+ + C+ GHP W K + + + +L+ D
Sbjct: 175 NPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSD 234
Query: 185 AGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTL 244
AG YVC N S+ ++L V + P +R S L + V+ +++
Sbjct: 235 AGKYVCVGTNMVGERESEVAELTVLERPSFVKRP------SNLAVTVDDSAE-------- 280
Query: 245 VLQCVAVGSPIPHYQWFKN--ELPLTH------ETKKLYMVPYVDLEHQGTYWCHVYN 294
+C A G P+P +W K+ ELP + T K+ V D+ G+Y C N
Sbjct: 281 -FKCEARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDM---GSYTCVAEN 334
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 54.7 bits (130), Expect = 3e-07
Identities = 52/206 (25%), Positives = 82/206 (39%), Gaps = 28/206 (13%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFN 178
+++L PP I+ E VL GQ L C TGHP + WFK + + G+ + +
Sbjct: 1247 VEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPD 1306
Query: 179 AV-------HVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICV 231
V ++ AG Y C + N E ++ QL V P + D E
Sbjct: 1307 GVLLQVLQANLSSAGHYSC-IAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVN 1365
Query: 232 EPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVP--------YVDLE 283
P S L C A+ P P+ W K+ P ++ + ++P E
Sbjct: 1366 NPIS----------LICEALAFPSPNITWMKDGAPF-EASRNIQLLPGTHGLQILNAQKE 1414
Query: 284 HQGTYWCHVYND-RDSQDSKKVEIII 308
G Y C V N+ ++ + VE++I
Sbjct: 1415 DAGQYTCVVTNELGEAVKNYHVEVLI 1440
Score = 52.0 bits (123), Expect = 2e-06
Identities = 46/177 (25%), Positives = 71/177 (40%), Gaps = 21/177 (11%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFK-----MNKEIPNGNTS 173
LQ+ PP ++ V+ G V+L C A G P W K +++ + G +
Sbjct: 2208 LQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPSL 2267
Query: 174 ELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEP 233
+L AV D+G Y C V + E + QL V + P ++ +P
Sbjct: 2268 QL--EAVGAGDSGTYSC-VAVSEAGEARRHFQLTVMEPPH-------------IEDSGQP 2311
Query: 234 TSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWC 290
T L PG+ + L C A G+P P+ W K+ LT + + G Y C
Sbjct: 2312 TELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATRVLRVRDAGLYTC 2368
Score = 51.2 bits (121), Expect = 4e-06
Identities = 53/218 (24%), Positives = 84/218 (38%), Gaps = 30/218 (13%)
Query: 90 LCLLKLMGEKGCTVTELSDFLQAMEHTE-VLQLLSPPGIKITVNPESKAVLAGQFVKLCC 148
L L +L + T T +++ QA + V+ +L P I+ + VL GQ V+L C
Sbjct: 1989 LQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDC 2048
Query: 149 RATGHPFVQYQWFKMNKEIPNG---------NTSELIFNAVHVKDAGFYVCRVNNNFTFE 199
A G P W K + + L+ + DAG Y C V +N E
Sbjct: 2049 EADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTC-VAHNPAGE 2107
Query: 200 FSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQ 259
++ ++V +P + ++ DG + PG + + C GSP H
Sbjct: 2108 DARLHTVNVL-VPPTIKQGADGSGTLVSR-----------PGELVTMVCPVRGSPPIHVS 2155
Query: 260 WFKNELP-------LTHETKKLYMVPYVDLEHQGTYWC 290
W K+ LP L H + + V L G + C
Sbjct: 2156 WLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTC 2193
Score = 48.9 bits (115), Expect = 2e-05
Identities = 41/161 (25%), Positives = 62/161 (38%), Gaps = 20/161 (12%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNT------ 172
L++ +PP I + AV+ V+L C A G P WFK +P
Sbjct: 304 LRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRG 363
Query: 173 -SELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICV 231
+L DAG Y C+ +N + ++LDV P +++G
Sbjct: 364 GRQLQLGRAQSSDAGVYTCKA-SNAVGAAEKATRLDVYVPP-----TIEGAGG------- 410
Query: 232 EPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETK 272
P K + G + L+CVA G P P W LP+ +
Sbjct: 411 RPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNE 451
Score = 48.9 bits (115), Expect = 2e-05
Identities = 58/235 (24%), Positives = 93/235 (39%), Gaps = 32/235 (13%)
Query: 78 SLKVLEPEGSPSLCLLKLMG-EKGCTVTELSDFLQAMEHTEVLQLLSPPGIK-ITVNPES 135
S KV+ G L L + + G + S+ + A E L + PP I+ P
Sbjct: 355 STKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYV 414
Query: 136 KAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAVHVK-------DAGFY 188
+AG+ V L C A GHP W + N S L + ++ +G Y
Sbjct: 415 VKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLY 474
Query: 189 VCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQC 248
C ++ Q+S ++V P+ V+E Q+ + G L L C
Sbjct: 475 SCVASSPAGEAVLQYS-VEVQVPPQLL------VAEGLGQVTT-------IVGQPLELPC 520
Query: 249 VAVGSPIPHYQWFKNELP--------LTHETKKLYMVPYVDLEHQGTYWCHVYND 295
A GSP+P QW +N P + + L+ + +V+L+H G + C N+
Sbjct: 521 QASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLH-IDHVELDHSGLFACQATNE 574
Score = 44.7 bits (104), Expect = 4e-04
Identities = 51/190 (26%), Positives = 79/190 (41%), Gaps = 28/190 (14%)
Query: 130 TVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNT-----SELIFNAVHVKD 184
T P +++ G + L C A G P + W ++ + G + S L AV +D
Sbjct: 2941 TTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSRED 3000
Query: 185 AGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTL 244
+G YVC N S + V + P + G + S L VEP G ++
Sbjct: 3001 SGTYVCWAENRVG-RTQAVSFVHVKEAPV-----LQGEAFSYL---VEPV------GGSI 3045
Query: 245 VLQCVAVGSPIPHYQWFKNELPL--THETKKL----YMVPYVDLEHQGTYWCHVYNDRDS 298
L CV G P+P W K+ LPL +H +L + + + G Y C N+
Sbjct: 3046 QLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGV 3105
Query: 299 QDSKKVEIII 308
+KKV I++
Sbjct: 3106 --AKKVVILV 3113
Score = 43.9 bits (102), Expect = 6e-04
Identities = 48/166 (28%), Positives = 68/166 (40%), Gaps = 42/166 (25%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPN--GNTSE-- 174
L++L PP I+ P +KAVL V L C A+G P WFK ++ + + G T
Sbjct: 689 LKVLVPPNIE--PGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVD 746
Query: 175 ---LIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESK--LQI 229
L + DAG Y C +N V G +E + L++
Sbjct: 747 GRVLRIEQAQLSDAGSYRCVASN------------------------VAGSTELRYGLRV 782
Query: 230 CVEP--TSQKLMPGSTLV-----LQCVAVGSPIPHYQWFKNELPLT 268
V P T +PG LV L C A G+P P W K+ P++
Sbjct: 783 NVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVS 828
Score = 43.1 bits (100), Expect = 0.001
Identities = 44/191 (23%), Positives = 75/191 (39%), Gaps = 23/191 (12%)
Query: 85 EGSPSLCLLKL-MGEKGC-TVTELSDFLQAMEHTEVLQLLSPPGIKITVNPESKAVLAGQ 142
E PSL L + G+ G + +S+ +A H + L ++ PP I+ + P ++ G
Sbjct: 2262 EQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQ-LTVMEPPHIEDSGQPTELSLTPGA 2320
Query: 143 FVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQ 202
++L C A G P W K + + + + V+DAG Y C
Sbjct: 2321 PMELLCDAQGTPQPNITWHKDGQALTRLENNSRATRVLRVRDAGLYTC------------ 2368
Query: 203 WSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPG---STLVLQCVAVGSPIPHYQ 259
++ I +SF+ V V P + + G LVL+C P P
Sbjct: 2369 LAESPAGAIEKSFRVRVQAPPN-----IVGPRGPRFVVGLAPGQLVLECSVEAEPAPKIT 2423
Query: 260 WFKNELPLTHE 270
W ++ + L +
Sbjct: 2424 WHRDGIVLQED 2434
Score = 42.0 bits (97), Expect = 0.002
Identities = 47/188 (25%), Positives = 68/188 (36%), Gaps = 35/188 (18%)
Query: 134 ESKAVLAGQFVKLCCRATGHPFVQYQWFK--------MNKEIPNGNTSELIFNAVHVKDA 185
E V + L C A P W K N ++ G I NA +DA
Sbjct: 1358 EEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNA-QKEDA 1416
Query: 186 GFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVD----GVSESKLQICVEPTSQKLMPG 241
G Y C V N + ++V IP S + GV E K ++
Sbjct: 1417 GQYTCVVTNELGEAVKNY-HVEVL-IPPSISKDDPLGEVGVKEVKTKV-----------N 1463
Query: 242 STLVLQCVAVGSPIPHYQWFKNELPLTHETK-------KLYMVPYVDLEHQGTYWCHVYN 294
STL L+C + P P +W+K+ P+T ++ +L + + G Y C N
Sbjct: 1464 STLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATN 1523
Query: 295 --DRDSQD 300
D QD
Sbjct: 1524 VAGEDDQD 1531
Score = 42.0 bits (97), Expect = 0.002
Identities = 42/181 (23%), Positives = 69/181 (38%), Gaps = 41/181 (22%)
Query: 133 PESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELI----FNAVHV--KDAG 186
P +A + V L C A+G P W K + G +++++ H +DAG
Sbjct: 2763 PSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAG 2822
Query: 187 FYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMP------ 240
Y+C N+ + + +++L + V P + +P
Sbjct: 2823 NYLCIAKNS----------------------AGSAMGKTRLVVQVPPVIENGLPDLSTTE 2860
Query: 241 GSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDL-------EHQGTYWCHVY 293
GS L C A GSP P+ W K+ P++ K + P +L + GTY C
Sbjct: 2861 GSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAE 2920
Query: 294 N 294
N
Sbjct: 2921 N 2921
Score = 41.2 bits (95), Expect = 0.004
Identities = 40/170 (23%), Positives = 61/170 (35%), Gaps = 36/170 (21%)
Query: 141 GQFVKLCCRATGHPFVQYQWFK---------MNKEIPNGNTSELIFNAVHVKDAGFYVCR 191
G ++L C G P W K + ++ NG+ L + DAG Y C
Sbjct: 3042 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGS---LTIHRTERDDAGRYQCL 3098
Query: 192 VNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAV 251
N ++ V V +S VEP + G + L+C A
Sbjct: 3099 AENEMGVA----------------KKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQAT 3142
Query: 252 GSPIPHYQWFKNELPLTHETKKLYMVP-------YVDLEHQGTYWCHVYN 294
G P P +W + PL +++L +P V+ GTY C +N
Sbjct: 3143 GEPTPTIEWLQAGQPL-RASRRLRTLPDGSLWLENVETGDAGTYDCVAHN 3191
Score = 40.4 bits (93), Expect = 0.007
Identities = 46/198 (23%), Positives = 69/198 (34%), Gaps = 43/198 (21%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQF-VKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIF 177
L +L PP + ++P + A + L C A G P +WF+ + + G + L+
Sbjct: 1153 LSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLA 1212
Query: 178 NAVHVK-------DAGFYVCRVNN-------NFTFEFSQWSQLDVCDIPESFQRSVDGVS 223
+K D+G Y C +N NF+ E ++ D+ E
Sbjct: 1213 GGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVI-------- 1264
Query: 224 ESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKK-------LYM 276
K++ G T L C G P P WFK+ PL L
Sbjct: 1265 -------------KVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQ 1311
Query: 277 VPYVDLEHQGTYWCHVYN 294
V +L G Y C N
Sbjct: 1312 VLQANLSSAGHYSCIAAN 1329
Score = 40.4 bits (93), Expect = 0.007
Identities = 44/190 (23%), Positives = 72/190 (37%), Gaps = 27/190 (14%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNG-------N 171
L++ PP I ++ E + V L C HP + W+K ++ + G
Sbjct: 1740 LRVQVPPRIA-GLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPG 1798
Query: 172 TSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICV 231
T L + D+G Y C N + + QL V +P +F+++ G ++ L
Sbjct: 1799 THTLQLGRARLSDSGMYTCEALNAAGRD-QKLVQLSVL-VPPAFRQAPRGPQDAVL---- 1852
Query: 232 EPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELP--LTHETKKL-----YMVPYVDLEH 284
+ G VL C P P W+K+ P L T+ L + +
Sbjct: 1853 ------VRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSD 1906
Query: 285 QGTYWCHVYN 294
+G Y C V N
Sbjct: 1907 KGLYSCKVSN 1916
Score = 40.4 bits (93), Expect = 0.007
Identities = 40/158 (25%), Positives = 58/158 (36%), Gaps = 24/158 (15%)
Query: 119 LQLLSPPGIKITVNPESKAVLA--GQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELI 176
L +L PP + AVL G L C P W+K + + ++ +
Sbjct: 1832 LSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQAL 1891
Query: 177 -------FNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQI 229
V D G Y C+V+N E + L V +P +F+
Sbjct: 1892 RGGQRLEIQEAQVSDKGLYSCKVSN-VAGEAVRTFTLTV-QVPPTFENPK---------- 1939
Query: 230 CVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPL 267
E SQ + GS LVL C G P P W K+ +P+
Sbjct: 1940 -TETVSQ--VAGSPLVLTCDVSGVPAPTVTWLKDRMPV 1974
Score = 39.3 bits (90), Expect = 0.015
Identities = 36/181 (19%), Positives = 69/181 (38%), Gaps = 26/181 (14%)
Query: 134 ESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNA-------VHVKDAG 186
E + ++ L C P W++ ++ + G+ ++ V ++AG
Sbjct: 1567 EYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAG 1626
Query: 187 FYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVL 246
Y C+ +N ++ + L V P + + V E + ST+ L
Sbjct: 1627 RYSCKASNEVGEDWLHYELL-VLTPPVILGDTEELVEEVTVNA-----------SSTVSL 1674
Query: 247 QCVAVGSPIPHYQWFKNELPLTH-------ETKKLYMVPYVDLEHQGTYWCHVYNDRDSQ 299
QC A+G+P+P W +N LP + E ++ V ++ +Y C N S
Sbjct: 1675 QCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSA 1734
Query: 300 D 300
+
Sbjct: 1735 E 1735
Score = 37.0 bits (84), Expect = 0.073
Identities = 46/185 (24%), Positives = 70/185 (37%), Gaps = 19/185 (10%)
Query: 119 LQLLSPPGIKITVNPESKA-VLAGQFVKLCCRATGHPFVQYQWFKMNKEI-PNGNTSELI 176
L++ PP +IT+ P VL V+L C ATG P W K + P G +
Sbjct: 780 LRVNVPP--RITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQV 837
Query: 177 FNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQ 236
F G V + + + ++S + V + E Q V V I E +
Sbjct: 838 F-------PGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQV-HMPPSILGEELNV 889
Query: 237 KLMPGSTLVLQCVAVGSPIPHYQWFKNELPL-------THETKKLYMVPYVDLEHQGTYW 289
++ ++ L+C + P P W+K+ PL K L V D+ G Y
Sbjct: 890 SVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYT 949
Query: 290 CHVYN 294
C N
Sbjct: 950 CEALN 954
Score = 36.6 bits (83), Expect = 0.096
Identities = 40/169 (23%), Positives = 60/169 (35%), Gaps = 38/169 (22%)
Query: 123 SPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEI-PNG-------NTSE 174
+PP + + LAG V+L C +G P Q +W K + + P G +
Sbjct: 214 APPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQV 273
Query: 175 LIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPT 234
L HV D G Y C +F + + +L++ PT
Sbjct: 274 LRITGSHVGDEGRYQC----------------------VAFSPAGQQARDFQLRVHAPPT 311
Query: 235 --------SQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLY 275
+M + L C A G P P+ WFK+ L TK +Y
Sbjct: 312 IWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVY 360
Score = 36.2 bits (82), Expect = 0.13
Identities = 39/156 (25%), Positives = 58/156 (37%), Gaps = 32/156 (20%)
Query: 115 HTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEI-PNGNTS 173
HT PP + ++VN Q L C+A G P W K + P
Sbjct: 2479 HTVPTIRSGPPAVNVSVN---------QTALLPCQADGVPAPLVSWRKDRVPLDPRSPRF 2529
Query: 174 ELI------FNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKL 227
E++ V +DAG Y+C +N+ + Q L V + P
Sbjct: 2530 EILPEGSLRIQPVLAQDAGHYLCLASNSAGSD-RQGRDLRVLEPPA-------------- 2574
Query: 228 QICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKN 263
I P++ L + +L C A GSP P W+K+
Sbjct: 2575 -IAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKD 2609
Score = 35.8 bits (81), Expect = 0.16
Identities = 42/174 (24%), Positives = 60/174 (34%), Gaps = 31/174 (17%)
Query: 138 VLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAV---------HVKDAGFY 188
V G L C G PF + W K + +P +AV + G Y
Sbjct: 983 VREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTY 1042
Query: 189 VCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQC 248
C +N SQ QL+V P+ + G E PT ++ L+C
Sbjct: 1043 TCECSN-VVGNSSQDLQLEVHVPPQ-----IAGPREP-------PTQVSVVQDGVATLEC 1089
Query: 249 VAVGSPIPHYQWFKNELP--------LTHETKKLYMVPYVDLEHQGTYWCHVYN 294
A G P P W ++ P L ++ + L+ V H G Y C N
Sbjct: 1090 NATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLH-VERAQAAHTGRYSCVAEN 1142
Score = 35.0 bits (79), Expect = 0.28
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 14/86 (16%)
Query: 118 VLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMN---------KEIP 168
+L L S P + V P+ V +G V L C+ATG P +W + + +P
Sbjct: 3111 ILVLQSAPVFQ--VEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLP 3168
Query: 169 NGNTSELIFNAVHVKDAGFYVCRVNN 194
+G+ L V DAG Y C +N
Sbjct: 3169 DGS---LWLENVETGDAGTYDCVAHN 3191
Score = 33.5 bits (75), Expect = 0.81
Identities = 45/212 (21%), Positives = 76/212 (35%), Gaps = 34/212 (16%)
Query: 112 AMEHTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGN 171
A+E + +++ +PP I P LA + L C P + W + +
Sbjct: 2376 AIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQEDA 2435
Query: 172 TSE-------LIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSE 224
++ L A+ D+G Y C N S ++++ +P
Sbjct: 2436 HTQFPERGRFLQLQALSTADSGDYSCTARNA-AGSTSVAFRVEIHTVPT----------- 2483
Query: 225 SKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEH 284
I P + + T +L C A G P P W K+ +PL + + ++P L
Sbjct: 2484 ----IRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRI 2539
Query: 285 Q-------GTYWCHVYN----DRDSQDSKKVE 305
Q G Y C N DR +D + +E
Sbjct: 2540 QPVLAQDAGHYLCLASNSAGSDRQGRDLRVLE 2571
Score = 33.1 bits (74), Expect = 1.1
Identities = 16/69 (23%), Positives = 31/69 (44%), Gaps = 7/69 (10%)
Query: 233 PTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLT-------HETKKLYMVPYVDLEHQ 285
P ++ ++ +++ L+C+A G P P WFK P++ ++ + L
Sbjct: 701 PVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDA 760
Query: 286 GTYWCHVYN 294
G+Y C N
Sbjct: 761 GSYRCVASN 769
Score = 32.0 bits (71), Expect = 2.4
Identities = 51/229 (22%), Positives = 93/229 (40%), Gaps = 29/229 (12%)
Query: 96 MGEKGCTVTELSDFLQAMEHTEVLQLLSPPGIKITVNPESK-AVLAGQFVKLCCRATGHP 154
+ ++G E S+ + L++ PP I P ++ +V+ L C ATG P
Sbjct: 1036 LAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKP 1095
Query: 155 FVQYQWFKMNKEIPN--GNTSELIFNAVHVKDA-----GFYVCRVNNNFTFEFSQWSQLD 207
W + + + G + ++HV+ A G Y C V N + +L
Sbjct: 1096 PPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSC-VAENLAGRAERKFELS 1154
Query: 208 VCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPL 267
V +P +D ++ + S L L C A+G P P +WF+ E P+
Sbjct: 1155 VL-VPPELIGDLDPLTNITAAL-----------HSPLTLLCEAMGIPPPAIRWFRGEEPV 1202
Query: 268 T--HETKKL---YMVPYVDLEHQ--GTYWCHVYNDR-DSQDSKKVEIII 308
+ +T L +M+ + Q G Y C N+ +++ + VE+++
Sbjct: 1203 SPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLV 1251
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 54.7 bits (130), Expect = 3e-07
Identities = 52/206 (25%), Positives = 82/206 (39%), Gaps = 28/206 (13%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFN 178
+++L PP I+ E VL GQ L C TGHP + WFK + + G+ + +
Sbjct: 2438 VEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPD 2497
Query: 179 AV-------HVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICV 231
V ++ AG Y C + N E ++ QL V P + D E
Sbjct: 2498 GVLLQVLQANLSSAGHYSC-IAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVN 2556
Query: 232 EPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVP--------YVDLE 283
P S L C A+ P P+ W K+ P ++ + ++P E
Sbjct: 2557 NPIS----------LICEALAFPSPNITWMKDGAPF-EASRNIQLLPGTHGLQILNAQKE 2605
Query: 284 HQGTYWCHVYND-RDSQDSKKVEIII 308
G Y C V N+ ++ + VE++I
Sbjct: 2606 DAGQYTCVVTNELGEAVKNYHVEVLI 2631
Score = 52.0 bits (123), Expect = 2e-06
Identities = 46/177 (25%), Positives = 71/177 (40%), Gaps = 21/177 (11%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFK-----MNKEIPNGNTS 173
LQ+ PP ++ V+ G V+L C A G P W K +++ + G +
Sbjct: 3399 LQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPSL 3458
Query: 174 ELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEP 233
+L AV D+G Y C V + E + QL V + P ++ +P
Sbjct: 3459 QL--EAVGAGDSGTYSC-VAVSEAGEARRHFQLTVMEPPH-------------IEDSGQP 3502
Query: 234 TSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWC 290
T L PG+ + L C A G+P P+ W K+ LT + + G Y C
Sbjct: 3503 TELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATRVLRVRDAGLYTC 3559
Score = 51.2 bits (121), Expect = 4e-06
Identities = 63/244 (25%), Positives = 96/244 (39%), Gaps = 28/244 (11%)
Query: 59 ELAGSRGRLRLSCLDLEQCSLKVLEPEGSPSLCLLKLMGEKGCTVTELSDFLQAMEHTEV 118
E+ S RL LS E+ L P GS L +++ G+ G S+ + H V
Sbjct: 1058 EMRLSVNRLALSKYVWEEYGLL---PSGSLRLAQVQV-GDSGHYECTASNPAGSASHRYV 1113
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIP-NGNTSELIF 177
L + PP ++ P VL G+ + L C A G+P Q W K + G + F
Sbjct: 1114 LGVQVPP--QVQPGPRVLKVLVGEALDLNCVAEGNPEPQLSWSKDGVVLQGRGPQGSVHF 1171
Query: 178 NAVHVKDAGFYVCRVNNNFTFEFSQWS-QLDVCDIPESFQRSVDGVSESKLQICVEPTSQ 236
A+ DAG Y C +N+ + W +L V + P G+ E
Sbjct: 1172 AAIRTSDAGRYRCEASNSAGVD--AWEVELRVLEPPHWGADETSGLLER----------- 1218
Query: 237 KLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWCHVYNDR 296
+ G L C A G+P P W K ++ L+ P V + +G+ + +
Sbjct: 1219 --VAGENASLPCPARGTPKPQVTWRKGP-----SSEPLHGQPGVAVLEEGSLFLASVSPA 1271
Query: 297 DSQD 300
DS D
Sbjct: 1272 DSGD 1275
Score = 51.2 bits (121), Expect = 4e-06
Identities = 53/218 (24%), Positives = 84/218 (38%), Gaps = 30/218 (13%)
Query: 90 LCLLKLMGEKGCTVTELSDFLQAMEHTE-VLQLLSPPGIKITVNPESKAVLAGQFVKLCC 148
L L +L + T T +++ QA + V+ +L P I+ + VL GQ V+L C
Sbjct: 3180 LQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDC 3239
Query: 149 RATGHPFVQYQWFKMNKEIPNG---------NTSELIFNAVHVKDAGFYVCRVNNNFTFE 199
A G P W K + + L+ + DAG Y C V +N E
Sbjct: 3240 EADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTC-VAHNPAGE 3298
Query: 200 FSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQ 259
++ ++V +P + ++ DG + PG + + C GSP H
Sbjct: 3299 DARLHTVNVL-VPPTIKQGADGSGTLVSR-----------PGELVTMVCPVRGSPPIHVS 3346
Query: 260 WFKNELP-------LTHETKKLYMVPYVDLEHQGTYWC 290
W K+ LP L H + + V L G + C
Sbjct: 3347 WLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTC 3384
Score = 48.9 bits (115), Expect = 2e-05
Identities = 41/161 (25%), Positives = 62/161 (38%), Gaps = 20/161 (12%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNT------ 172
L++ +PP I + AV+ V+L C A G P WFK +P
Sbjct: 1495 LRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRG 1554
Query: 173 -SELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICV 231
+L DAG Y C+ +N + ++LDV P +++G
Sbjct: 1555 GRQLQLGRAQSSDAGVYTCKA-SNAVGAAEKATRLDVYVPP-----TIEGAGG------- 1601
Query: 232 EPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETK 272
P K + G + L+CVA G P P W LP+ +
Sbjct: 1602 RPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNE 1642
Score = 48.9 bits (115), Expect = 2e-05
Identities = 58/235 (24%), Positives = 93/235 (39%), Gaps = 32/235 (13%)
Query: 78 SLKVLEPEGSPSLCLLKLMG-EKGCTVTELSDFLQAMEHTEVLQLLSPPGIK-ITVNPES 135
S KV+ G L L + + G + S+ + A E L + PP I+ P
Sbjct: 1546 STKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYV 1605
Query: 136 KAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAVHVK-------DAGFY 188
+AG+ V L C A GHP W + N S L + ++ +G Y
Sbjct: 1606 VKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLY 1665
Query: 189 VCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQC 248
C ++ Q+S ++V P+ V+E Q+ + G L L C
Sbjct: 1666 SCVASSPAGEAVLQYS-VEVQVPPQLL------VAEGLGQVTT-------IVGQPLELPC 1711
Query: 249 VAVGSPIPHYQWFKNELP--------LTHETKKLYMVPYVDLEHQGTYWCHVYND 295
A GSP+P QW +N P + + L+ + +V+L+H G + C N+
Sbjct: 1712 QASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLH-IDHVELDHSGLFACQATNE 1765
Score = 45.4 bits (106), Expect = 2e-04
Identities = 70/289 (24%), Positives = 107/289 (37%), Gaps = 49/289 (16%)
Query: 20 PLLAPPAGATLNRLREPLLRRLSELLDQAPEGRGW-RRLAELAGSRGRL-RLSCLDLEQC 77
P L P T++ +L +L +AP W R L S GR+ +L+ L LE
Sbjct: 518 PQLVPAPNVTVSPGETAVLS--CRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEIS 575
Query: 78 SLKVLEPEGSPSLCLLKLMGEKGCTVTELSDFLQAMEHTEVLQLLSPPGIKITVNPESKA 137
++ +G C+ VT S +L E +V +++ S+
Sbjct: 576 G--IIPTDGGRYQCV----ASNANGVTRASVWLLVREAPQV-----------SIHTSSQH 618
Query: 138 VLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNT------SELIFNAVHVKDAGFYVCR 191
G VK+ C A+G+P W + ++ + + LI V +DAG Y C+
Sbjct: 619 FSQGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQ 678
Query: 192 VNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAV 251
N + + L D P SV V+ L + G VL C A
Sbjct: 679 ATNEVGTD-QETVTLYYTDPP-----SVSAVNAVVL----------VAVGEEAVLVCEAS 722
Query: 252 GSPIPHYQWFKNEL-----PLTHETKKLYMVPYVDLEHQGTYWCHVYND 295
G P P W++ L P + KL +P GTY C N+
Sbjct: 723 GVPPPRVIWYRGGLEMILAPEGSSSGKL-RIPAAQERDAGTYTCRAVNE 770
Score = 44.7 bits (104), Expect = 4e-04
Identities = 66/274 (24%), Positives = 103/274 (37%), Gaps = 51/274 (18%)
Query: 81 VLEPEGSPSLCLL------KLMGEKGC-TVTELSDFLQAMEHTEVLQLLSPPGIKITVNP 133
+L PEGS S L + G C V EL D + +QL ++T P
Sbjct: 739 ILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDA------SAEIQLAVGHAPQLTELP 792
Query: 134 ESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNG--------------NTSELIFNA 179
V G+ L CRATG P W + + + P G ++ L F +
Sbjct: 793 RDVTVELGRSALLACRATGRPPPTVTWRRGDGQ-PLGLRLGAGRGSRSRQPDSGVLFFES 851
Query: 180 VHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLM 239
V +D YVC N F + + V G + QI + +++
Sbjct: 852 VAPEDQAPYVCEARNVFG------------KVQAEARLIVTG--HAPPQIASSAPTVRVL 897
Query: 240 PGSTLVLQCVAV-GSPIPHYQWFKNELPLTHETKKLYMVP---YVD---LEHQGTYWCHV 292
G + L C+ + G P+P W K+ PL ++ ++D EH G Y C
Sbjct: 898 EGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVA 957
Query: 293 YNDRDSQDSKKVEIIIDELNNLGHPDNKEQTTDQ 326
N SQ + VE+++ + HP T++
Sbjct: 958 TNTAGSQ-HRDVELVVQVPPRI-HPTATHHITNE 989
Score = 44.7 bits (104), Expect = 4e-04
Identities = 51/190 (26%), Positives = 79/190 (41%), Gaps = 28/190 (14%)
Query: 130 TVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNT-----SELIFNAVHVKD 184
T P +++ G + L C A G P + W ++ + G + S L AV +D
Sbjct: 4132 TTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSRED 4191
Query: 185 AGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTL 244
+G YVC N S + V + P + G + S L VEP G ++
Sbjct: 4192 SGTYVCWAENRVG-RTQAVSFVHVKEAPV-----LQGEAFSYL---VEPV------GGSI 4236
Query: 245 VLQCVAVGSPIPHYQWFKNELPL--THETKKL----YMVPYVDLEHQGTYWCHVYNDRDS 298
L CV G P+P W K+ LPL +H +L + + + G Y C N+
Sbjct: 4237 QLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGV 4296
Query: 299 QDSKKVEIII 308
+KKV I++
Sbjct: 4297 --AKKVVILV 4304
Score = 43.9 bits (102), Expect = 6e-04
Identities = 48/166 (28%), Positives = 68/166 (40%), Gaps = 42/166 (25%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPN--GNTSE-- 174
L++L PP I+ P +KAVL V L C A+G P WFK ++ + + G T
Sbjct: 1880 LKVLVPPNIE--PGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVD 1937
Query: 175 ---LIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESK--LQI 229
L + DAG Y C +N V G +E + L++
Sbjct: 1938 GRVLRIEQAQLSDAGSYRCVASN------------------------VAGSTELRYGLRV 1973
Query: 230 CVEP--TSQKLMPGSTLV-----LQCVAVGSPIPHYQWFKNELPLT 268
V P T +PG LV L C A G+P P W K+ P++
Sbjct: 1974 NVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVS 2019
Score = 43.1 bits (100), Expect = 0.001
Identities = 44/191 (23%), Positives = 75/191 (39%), Gaps = 23/191 (12%)
Query: 85 EGSPSLCLLKL-MGEKGC-TVTELSDFLQAMEHTEVLQLLSPPGIKITVNPESKAVLAGQ 142
E PSL L + G+ G + +S+ +A H + L ++ PP I+ + P ++ G
Sbjct: 3453 EQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQ-LTVMEPPHIEDSGQPTELSLTPGA 3511
Query: 143 FVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQ 202
++L C A G P W K + + + + V+DAG Y C
Sbjct: 3512 PMELLCDAQGTPQPNITWHKDGQALTRLENNSRATRVLRVRDAGLYTC------------ 3559
Query: 203 WSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPG---STLVLQCVAVGSPIPHYQ 259
++ I +SF+ V V P + + G LVL+C P P
Sbjct: 3560 LAESPAGAIEKSFRVRVQAPPN-----IVGPRGPRFVVGLAPGQLVLECSVEAEPAPKIT 3614
Query: 260 WFKNELPLTHE 270
W ++ + L +
Sbjct: 3615 WHRDGIVLQED 3625
Score = 42.0 bits (97), Expect = 0.002
Identities = 47/188 (25%), Positives = 68/188 (36%), Gaps = 35/188 (18%)
Query: 134 ESKAVLAGQFVKLCCRATGHPFVQYQWFK--------MNKEIPNGNTSELIFNAVHVKDA 185
E V + L C A P W K N ++ G I NA +DA
Sbjct: 2549 EEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNA-QKEDA 2607
Query: 186 GFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVD----GVSESKLQICVEPTSQKLMPG 241
G Y C V N + ++V IP S + GV E K ++
Sbjct: 2608 GQYTCVVTNELGEAVKNY-HVEVL-IPPSISKDDPLGEVGVKEVKTKV-----------N 2654
Query: 242 STLVLQCVAVGSPIPHYQWFKNELPLTHETK-------KLYMVPYVDLEHQGTYWCHVYN 294
STL L+C + P P +W+K+ P+T ++ +L + + G Y C N
Sbjct: 2655 STLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATN 2714
Query: 295 --DRDSQD 300
D QD
Sbjct: 2715 VAGEDDQD 2722
Score = 42.0 bits (97), Expect = 0.002
Identities = 42/181 (23%), Positives = 69/181 (38%), Gaps = 41/181 (22%)
Query: 133 PESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELI----FNAVHV--KDAG 186
P +A + V L C A+G P W K + G +++++ H +DAG
Sbjct: 3954 PSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAG 4013
Query: 187 FYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMP------ 240
Y+C N+ + + +++L + V P + +P
Sbjct: 4014 NYLCIAKNS----------------------AGSAMGKTRLVVQVPPVIENGLPDLSTTE 4051
Query: 241 GSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDL-------EHQGTYWCHVY 293
GS L C A GSP P+ W K+ P++ K + P +L + GTY C
Sbjct: 4052 GSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAE 4111
Query: 294 N 294
N
Sbjct: 4112 N 4112
Score = 41.2 bits (95), Expect = 0.004
Identities = 40/170 (23%), Positives = 61/170 (35%), Gaps = 36/170 (21%)
Query: 141 GQFVKLCCRATGHPFVQYQWFK---------MNKEIPNGNTSELIFNAVHVKDAGFYVCR 191
G ++L C G P W K + ++ NG+ L + DAG Y C
Sbjct: 4233 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGS---LTIHRTERDDAGRYQCL 4289
Query: 192 VNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAV 251
N ++ V V +S VEP + G + L+C A
Sbjct: 4290 AENEMGVA----------------KKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQAT 4333
Query: 252 GSPIPHYQWFKNELPLTHETKKLYMVP-------YVDLEHQGTYWCHVYN 294
G P P +W + PL +++L +P V+ GTY C +N
Sbjct: 4334 GEPTPTIEWLQAGQPL-RASRRLRTLPDGSLWLENVETGDAGTYDCVAHN 4382
Score = 40.4 bits (93), Expect = 0.007
Identities = 46/198 (23%), Positives = 69/198 (34%), Gaps = 43/198 (21%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQF-VKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIF 177
L +L PP + ++P + A + L C A G P +WF+ + + G + L+
Sbjct: 2344 LSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLA 2403
Query: 178 NAVHVK-------DAGFYVCRVNN-------NFTFEFSQWSQLDVCDIPESFQRSVDGVS 223
+K D+G Y C +N NF+ E ++ D+ E
Sbjct: 2404 GGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVI-------- 2455
Query: 224 ESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKK-------LYM 276
K++ G T L C G P P WFK+ PL L
Sbjct: 2456 -------------KVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQ 2502
Query: 277 VPYVDLEHQGTYWCHVYN 294
V +L G Y C N
Sbjct: 2503 VLQANLSSAGHYSCIAAN 2520
Score = 40.4 bits (93), Expect = 0.007
Identities = 44/190 (23%), Positives = 72/190 (37%), Gaps = 27/190 (14%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNG-------N 171
L++ PP I ++ E + V L C HP + W+K ++ + G
Sbjct: 2931 LRVQVPPRIA-GLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPG 2989
Query: 172 TSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICV 231
T L + D+G Y C N + + QL V +P +F+++ G ++ L
Sbjct: 2990 THTLQLGRARLSDSGMYTCEALNAAGRD-QKLVQLSVL-VPPAFRQAPRGPQDAVL---- 3043
Query: 232 EPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELP--LTHETKKL-----YMVPYVDLEH 284
+ G VL C P P W+K+ P L T+ L + +
Sbjct: 3044 ------VRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSD 3097
Query: 285 QGTYWCHVYN 294
+G Y C V N
Sbjct: 3098 KGLYSCKVSN 3107
Score = 40.4 bits (93), Expect = 0.007
Identities = 40/158 (25%), Positives = 58/158 (36%), Gaps = 24/158 (15%)
Query: 119 LQLLSPPGIKITVNPESKAVLA--GQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELI 176
L +L PP + AVL G L C P W+K + + ++ +
Sbjct: 3023 LSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQAL 3082
Query: 177 -------FNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQI 229
V D G Y C+V+N E + L V +P +F+
Sbjct: 3083 RGGQRLEIQEAQVSDKGLYSCKVSN-VAGEAVRTFTLTV-QVPPTFENPK---------- 3130
Query: 230 CVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPL 267
E SQ + GS LVL C G P P W K+ +P+
Sbjct: 3131 -TETVSQ--VAGSPLVLTCDVSGVPAPTVTWLKDRMPV 3165
Score = 39.3 bits (90), Expect = 0.015
Identities = 42/173 (24%), Positives = 63/173 (36%), Gaps = 38/173 (21%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEI-PNG------- 170
L +L+PP + + LAG V+L C +G P Q +W K + + P G
Sbjct: 1401 LLVLTPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQE 1460
Query: 171 NTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQIC 230
+ L HV D G Y C +F + + +L++
Sbjct: 1461 DGQVLRITGSHVGDEGRYQC----------------------VAFSPAGQQARDFQLRVH 1498
Query: 231 VEPT--------SQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLY 275
PT +M + L C A G P P+ WFK+ L TK +Y
Sbjct: 1499 APPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVY 1551
Score = 39.3 bits (90), Expect = 0.015
Identities = 36/181 (19%), Positives = 69/181 (38%), Gaps = 26/181 (14%)
Query: 134 ESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNA-------VHVKDAG 186
E + ++ L C P W++ ++ + G+ ++ V ++AG
Sbjct: 2758 EYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAG 2817
Query: 187 FYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVL 246
Y C+ +N ++ + L V P + + V E + ST+ L
Sbjct: 2818 RYSCKASNEVGEDWLHYELL-VLTPPVILGDTEELVEEVTVNA-----------SSTVSL 2865
Query: 247 QCVAVGSPIPHYQWFKNELPLTH-------ETKKLYMVPYVDLEHQGTYWCHVYNDRDSQ 299
QC A+G+P+P W +N LP + E ++ V ++ +Y C N S
Sbjct: 2866 QCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSA 2925
Query: 300 D 300
+
Sbjct: 2926 E 2926
Score = 37.0 bits (84), Expect = 0.073
Identities = 46/185 (24%), Positives = 70/185 (37%), Gaps = 19/185 (10%)
Query: 119 LQLLSPPGIKITVNPESKA-VLAGQFVKLCCRATGHPFVQYQWFKMNKEI-PNGNTSELI 176
L++ PP +IT+ P VL V+L C ATG P W K + P G +
Sbjct: 1971 LRVNVPP--RITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQV 2028
Query: 177 FNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQ 236
F G V + + + ++S + V + E Q V V I E +
Sbjct: 2029 F-------PGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQV-HMPPSILGEELNV 2080
Query: 237 KLMPGSTLVLQCVAVGSPIPHYQWFKNELPL-------THETKKLYMVPYVDLEHQGTYW 289
++ ++ L+C + P P W+K+ PL K L V D+ G Y
Sbjct: 2081 SVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYT 2140
Query: 290 CHVYN 294
C N
Sbjct: 2141 CEALN 2145
Score = 36.2 bits (82), Expect = 0.13
Identities = 41/153 (26%), Positives = 59/153 (38%), Gaps = 22/153 (14%)
Query: 119 LQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIP-NGNTS---- 173
L++L PP +AG+ L C A G P Q W K P +G
Sbjct: 1199 LRVLEPPHWGADETSGLLERVAGENASLPCPARGTPKPQVTWRKGPSSEPLHGQPGVAVL 1258
Query: 174 ---ELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQIC 230
L +V D+G Y C+ N S+ ++L V +P S + DG
Sbjct: 1259 EEGSLFLASVSPADSGDYECQATNEVG-STSRRAKL-VVYVPPSIRE--DG--------- 1305
Query: 231 VEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKN 263
+ M G +L L+C A G P+P W K+
Sbjct: 1306 -RKANVSGMAGQSLTLECDANGFPVPEIVWLKD 1337
Score = 36.2 bits (82), Expect = 0.13
Identities = 39/156 (25%), Positives = 58/156 (37%), Gaps = 32/156 (20%)
Query: 115 HTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEI-PNGNTS 173
HT PP + ++VN Q L C+A G P W K + P
Sbjct: 3670 HTVPTIRSGPPAVNVSVN---------QTALLPCQADGVPAPLVSWRKDRVPLDPRSPRF 3720
Query: 174 ELI------FNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKL 227
E++ V +DAG Y+C +N+ + Q L V + P
Sbjct: 3721 EILPEGSLRIQPVLAQDAGHYLCLASNSAGSD-RQGRDLRVLEPPA-------------- 3765
Query: 228 QICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKN 263
I P++ L + +L C A GSP P W+K+
Sbjct: 3766 -IAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKD 3800
Score = 35.8 bits (81), Expect = 0.16
Identities = 42/174 (24%), Positives = 60/174 (34%), Gaps = 31/174 (17%)
Query: 138 VLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAV---------HVKDAGFY 188
V G L C G PF + W K + +P +AV + G Y
Sbjct: 2174 VREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTY 2233
Query: 189 VCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQC 248
C +N SQ QL+V P+ + G E PT ++ L+C
Sbjct: 2234 TCECSN-VVGNSSQDLQLEVHVPPQ-----IAGPREP-------PTQVSVVQDGVATLEC 2280
Query: 249 VAVGSPIPHYQWFKNELP--------LTHETKKLYMVPYVDLEHQGTYWCHVYN 294
A G P P W ++ P L ++ + L+ V H G Y C N
Sbjct: 2281 NATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLH-VERAQAAHTGRYSCVAEN 2333
Score = 35.4 bits (80), Expect = 0.21
Identities = 43/172 (25%), Positives = 64/172 (37%), Gaps = 31/172 (18%)
Query: 123 SPPGIKITVNPESKAVLAGQFVKL-CCRATGHPFVQYQWFKMNKEIPNGNTSELIFN-AV 180
+PP +I + + VL GQ V L C G P + W K + +P G+ + + ++
Sbjct: 883 APP--QIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSL 940
Query: 181 HV-----KDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTS 235
H+ + AG Y C N S R V+ V + +I T
Sbjct: 941 HLDRALQEHAGRYSCVATNT----------------AGSQHRDVELVVQVPPRIHPTATH 984
Query: 236 QKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQGT 287
G L CVA G P P W K LT P+ ++ +GT
Sbjct: 985 HITNEGVPASLPCVASGVPAPTITWTKETNALTSRG------PHYNVSKEGT 1030
Score = 35.0 bits (79), Expect = 0.28
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 14/86 (16%)
Query: 118 VLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMN---------KEIP 168
+L L S P + V P+ V +G V L C+ATG P +W + + +P
Sbjct: 4302 ILVLQSAPVFQ--VEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLP 4359
Query: 169 NGNTSELIFNAVHVKDAGFYVCRVNN 194
+G+ L V DAG Y C +N
Sbjct: 4360 DGS---LWLENVETGDAGTYDCVAHN 4382
Score = 33.5 bits (75), Expect = 0.81
Identities = 45/212 (21%), Positives = 76/212 (35%), Gaps = 34/212 (16%)
Query: 112 AMEHTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGN 171
A+E + +++ +PP I P LA + L C P + W + +
Sbjct: 3567 AIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQEDA 3626
Query: 172 TSE-------LIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSE 224
++ L A+ D+G Y C N S ++++ +P
Sbjct: 3627 HTQFPERGRFLQLQALSTADSGDYSCTARNA-AGSTSVAFRVEIHTVPT----------- 3674
Query: 225 SKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEH 284
I P + + T +L C A G P P W K+ +PL + + ++P L
Sbjct: 3675 ----IRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRI 3730
Query: 285 Q-------GTYWCHVYN----DRDSQDSKKVE 305
Q G Y C N DR +D + +E
Sbjct: 3731 QPVLAQDAGHYLCLASNSAGSDRQGRDLRVLE 3762
Score = 33.1 bits (74), Expect = 1.1
Identities = 16/69 (23%), Positives = 31/69 (44%), Gaps = 7/69 (10%)
Query: 233 PTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLT-------HETKKLYMVPYVDLEHQ 285
P ++ ++ +++ L+C+A G P P WFK P++ ++ + L
Sbjct: 1892 PVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDA 1951
Query: 286 GTYWCHVYN 294
G+Y C N
Sbjct: 1952 GSYRCVASN 1960
Score = 32.0 bits (71), Expect = 2.4
Identities = 51/229 (22%), Positives = 93/229 (40%), Gaps = 29/229 (12%)
Query: 96 MGEKGCTVTELSDFLQAMEHTEVLQLLSPPGIKITVNPESK-AVLAGQFVKLCCRATGHP 154
+ ++G E S+ + L++ PP I P ++ +V+ L C ATG P
Sbjct: 2227 LAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKP 2286
Query: 155 FVQYQWFKMNKEIPN--GNTSELIFNAVHVKDA-----GFYVCRVNNNFTFEFSQWSQLD 207
W + + + G + ++HV+ A G Y C V N + +L
Sbjct: 2287 PPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSC-VAENLAGRAERKFELS 2345
Query: 208 VCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPL 267
V +P +D ++ + S L L C A+G P P +WF+ E P+
Sbjct: 2346 VL-VPPELIGDLDPLTNITAAL-----------HSPLTLLCEAMGIPPPAIRWFRGEEPV 2393
Query: 268 T--HETKKL---YMVPYVDLEHQ--GTYWCHVYNDR-DSQDSKKVEIII 308
+ +T L +M+ + Q G Y C N+ +++ + VE+++
Sbjct: 2394 SPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLV 2442
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,226,408
Number of Sequences: 37866
Number of extensions: 1615387
Number of successful extensions: 6667
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 113
Number of HSP's successfully gapped in prelim test: 216
Number of HSP's that attempted gapping in prelim test: 4644
Number of HSP's gapped (non-prelim): 1493
length of query: 813
length of database: 18,247,518
effective HSP length: 111
effective length of query: 702
effective length of database: 14,044,392
effective search space: 9859163184
effective search space used: 9859163184
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.