Search of human proteins with 27735143

Search of human proteins with 27735143

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27735143 discoidin, CUB and LCCL domain containing 1 [Homo
sapiens]
         (539 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27735143 discoidin, CUB and LCCL domain containing 1 [Homo sa...  1090   0.0  
gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo sa...   345   5e-95
gi|105990535 coagulation factor V precursor [Homo sapiens]            123   5e-28
gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Ho...   114   2e-25
gi|10518506 coagulation factor VIII isoform b precursor [Homo sa...   110   3e-24
gi|66864913 neuropilin 1 isoform c [Homo sapiens]                     110   3e-24
gi|66912178 neuropilin 1 isoform b [Homo sapiens]                     110   3e-24
gi|182508169 neuropilin 1 isoform a [Homo sapiens]                    110   3e-24
gi|4503647 coagulation factor VIII isoform a precursor [Homo sap...   110   3e-24
gi|31317224 EGF-like repeats and discoidin I-like domains-contai...   103   4e-22
gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]            94   2e-19
gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens]            94   2e-19
gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens]            94   2e-19
gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens]            94   2e-19
gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens]            94   2e-19
gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens]            94   2e-19
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo...    82   1e-15
gi|10835083 X-linked juvenile retinoschisis protein precursor [H...    81   3e-15
gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapi...    75   2e-13
gi|167830477 milk fat globule-EGF factor 8 protein isoform b [Ho...    72   1e-12
gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo sap...    71   2e-12
gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sap...    70   4e-12
gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sap...    70   4e-12
gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2...    69   1e-11
gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1...    69   1e-11
gi|239743729 PREDICTED: similar to contactin associated protein-...    69   1e-11
gi|47519929 cell recognition molecule CASPR3 [Homo sapiens]            69   1e-11
gi|18640734 contactin associated protein-like 5 [Homo sapiens]         68   2e-11
gi|126091152 cubilin [Homo sapiens]                                    67   4e-11
gi|21264363 mannan-binding lectin serine protease 2 isoform 1 pr...    66   9e-11

>gi|27735143 discoidin, CUB and LCCL domain containing 1 [Homo
           sapiens]
          Length = 539

 Score = 1090 bits (2818), Expect = 0.0
 Identities = 539/539 (100%), Positives = 539/539 (100%)

Query: 1   MVPGARGGGALARAAGRGLLALLLAVSAPLRLQAEELGDGCGHLVTYQDSGTMTSKNYPG 60
           MVPGARGGGALARAAGRGLLALLLAVSAPLRLQAEELGDGCGHLVTYQDSGTMTSKNYPG
Sbjct: 1   MVPGARGGGALARAAGRGLLALLLAVSAPLRLQAEELGDGCGHLVTYQDSGTMTSKNYPG 60

Query: 61  TYPNHTVCEKTITVPKGKRLILRLGDLDIESQTCASDYLLFTSSSDQYGPYCGSMTVPKE 120
           TYPNHTVCEKTITVPKGKRLILRLGDLDIESQTCASDYLLFTSSSDQYGPYCGSMTVPKE
Sbjct: 61  TYPNHTVCEKTITVPKGKRLILRLGDLDIESQTCASDYLLFTSSSDQYGPYCGSMTVPKE 120

Query: 121 LLLNTSEVTVRFESGSHISGRGFLLTYASSDHPDLITCLERASHYLKTEYSKFCPAGCRD 180
           LLLNTSEVTVRFESGSHISGRGFLLTYASSDHPDLITCLERASHYLKTEYSKFCPAGCRD
Sbjct: 121 LLLNTSEVTVRFESGSHISGRGFLLTYASSDHPDLITCLERASHYLKTEYSKFCPAGCRD 180

Query: 181 VAGDISGNMVDGYRDTSLLCKAAIHAGIIADELGGQISVLQRKGISRYEGILANGVLSRD 240
           VAGDISGNMVDGYRDTSLLCKAAIHAGIIADELGGQISVLQRKGISRYEGILANGVLSRD
Sbjct: 181 VAGDISGNMVDGYRDTSLLCKAAIHAGIIADELGGQISVLQRKGISRYEGILANGVLSRD 240

Query: 241 GSLSDKRFLFTSNGCSRSLSFEPDGQIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWA 300
           GSLSDKRFLFTSNGCSRSLSFEPDGQIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWA
Sbjct: 241 GSLSDKRFLFTSNGCSRSLSFEPDGQIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWA 300

Query: 301 SGDSSNNHKPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSFVMNFKNNNSKWKTYKG 360
           SGDSSNNHKPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSFVMNFKNNNSKWKTYKG
Sbjct: 301 SGDSSNNHKPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSFVMNFKNNNSKWKTYKG 360

Query: 361 IVNNEEKVFQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQRIALKVELIGCQITQGNDS 420
           IVNNEEKVFQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQRIALKVELIGCQITQGNDS
Sbjct: 361 IVNNEEKVFQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQRIALKVELIGCQITQGNDS 420

Query: 421 LVWRKTSQSTSVSTKKEDETITRPIPSEETSTGINITTVAIPLVLLVVLVFAGMGIFAAF 480
           LVWRKTSQSTSVSTKKEDETITRPIPSEETSTGINITTVAIPLVLLVVLVFAGMGIFAAF
Sbjct: 421 LVWRKTSQSTSVSTKKEDETITRPIPSEETSTGINITTVAIPLVLLVVLVFAGMGIFAAF 480

Query: 481 RKKKKKGSPYGSAEAQKTDCWKQIKYPFARHQSAEFTISYDNEKEMTQKLDLITSDMAG 539
           RKKKKKGSPYGSAEAQKTDCWKQIKYPFARHQSAEFTISYDNEKEMTQKLDLITSDMAG
Sbjct: 481 RKKKKKGSPYGSAEAQKTDCWKQIKYPFARHQSAEFTISYDNEKEMTQKLDLITSDMAG 539


>gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo
           sapiens]
          Length = 775

 Score =  345 bits (886), Expect = 5e-95
 Identities = 182/404 (45%), Positives = 255/404 (63%), Gaps = 14/404 (3%)

Query: 20  LALLLAVSAPLRLQAEELGDGCGHLVTYQDSGTMTSKNYPGTYPNHTVCEKTITVPKGKR 79
           L LLL +   L     + GDGCGH V   +SGT+TS NYP TYPN TVCE  I V  G+R
Sbjct: 51  LLLLLVLLLLLEDAGAQQGDGCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGER 110

Query: 80  LILRLGDLDIE-SQTCASDYLLFTS----SSDQYGPYCG-SMTVPKELLLNTSEVTVRFE 133
           + ++ GD DIE S +C  +YL   +    S  + G YCG  + +   +    +E+T+ F 
Sbjct: 111 VRIKFGDFDIEDSDSCHFNYLRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFM 170

Query: 134 SGSHISGRGFLLTYASSDHPDLITCLERASHYLKTEYSKFCPAGCRDVAGDISGNMVDGY 193
           SG H+SGRGFL +Y+  D  DLITCL+ AS++L+ E+SK+CPAGC     +ISG +  GY
Sbjct: 171 SGIHVSGRGFLASYSVIDKQDLITCLDTASNFLEPEFSKYCPAGCLLPFAEISGTIPHGY 230

Query: 194 RDTSLLCKAAIHAGIIADELGGQISVLQRKGISRYEGILANGVLSRDGSLSDKRFLFTSN 253
           RD+S LC A +HAG++++ LGGQISV+  KGI  YE  LAN V S  G LS   F F ++
Sbjct: 231 RDSSPLCMAGVHAGVVSNTLGGQISVVISKGIPYYESSLANNVTSVVGHLSTSLFTFKTS 290

Query: 254 GCSRSLSFE----PDGQIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNHK 309
           GC  +L  E     D QI ASS  +  + +G +  W P +ARL+  GP WA+  +     
Sbjct: 291 GCYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPGPPWAAFATDE--- 347

Query: 310 PREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVF 369
             +WL+IDL ++KKITGI TTGST    N+YV ++ + + ++  KW  Y+     ++K+F
Sbjct: 348 -YQWLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIF 406

Query: 370 QGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQRIALKVELIGCQ 413
           QGN ++   V+NNF+PPI+AR++RV P  W Q+IA+K+EL+GCQ
Sbjct: 407 QGNKDYHQDVRNNFLPPIIARFIRVNPTQWQQKIAMKMELLGCQ 450


>gi|105990535 coagulation factor V precursor [Homo sapiens]
          Length = 2224

 Score =  123 bits (308), Expect = 5e-28
 Identities = 72/169 (42%), Positives = 102/169 (60%), Gaps = 16/169 (9%)

Query: 253  NGCSRSLSFE----PDGQIRASS---SWQSVNESGDQVHWSPGQARLQDQGPSWASGDSS 305
            NGCS  L  E     + QI ASS   SW      GD  +W P +ARL  QG   A    +
Sbjct: 2064 NGCSTPLGMENGKIENKQITASSFKKSWW-----GD--YWEPFRARLNAQGRVNAWQAKA 2116

Query: 306  NNHKPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNE 365
            NN+K  +WLEIDL + KKIT I T G    +   YVKS+ +++     +WK Y+   +  
Sbjct: 2117 NNNK--QWLEIDLLKIKKITAIITQGCKSLSSEMYVKSYTIHYSEQGVEWKPYRLKSSMV 2174

Query: 366  EKVFQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQRIALKVELIGCQI 414
            +K+F+GN+N +  V+N F PPI++R++RV+P+TW+Q IAL++EL GC I
Sbjct: 2175 DKIFEGNTNTKGHVKNFFNPPIISRFIRVIPKTWNQSIALRLELFGCDI 2223



 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 42/133 (31%), Positives = 71/133 (53%), Gaps = 2/133 (1%)

Query: 284  HWSPGQARLQDQGP--SWASGDSSNNHKPREWLEIDLGEKKKITGIRTTGSTQSNFNFYV 341
            +W P  ARL + G   +W+    +     + W+++D+ ++  ITGI+T G+     + Y 
Sbjct: 1931 YWEPRLARLNNGGSYNAWSVEKLAAEFASKPWIQVDMQKEVIITGIQTQGAKHYLKSCYT 1990

Query: 342  KSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQ 401
              F + + +N   W+ +KG        F GNS+     +N F PPIVARY+R+ P   + 
Sbjct: 1991 TEFYVAYSSNQINWQIFKGNSTRNVMYFNGNSDASTIKENQFDPPIVARYIRISPTRAYN 2050

Query: 402  RIALKVELIGCQI 414
            R  L++EL GC++
Sbjct: 2051 RPTLRLELQGCEV 2063


>gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Homo
           sapiens]
          Length = 387

 Score =  114 bits (285), Expect = 2e-25
 Identities = 62/166 (37%), Positives = 94/166 (56%), Gaps = 12/166 (7%)

Query: 253 NGCSRSLSFE----PDGQIRASSSWQSVNESGDQVHWSPGQARLQDQGP--SWASGDSSN 306
           NGC+  L  +    PD QI ASSS+++         W+P  ARL  QG   +W +G   N
Sbjct: 228 NGCANPLGLKNNSIPDKQITASSSYKTWGLH--LFSWNPSYARLDKQGNFNAWVAGSYGN 285

Query: 307 NHKPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEE 366
           +    +WL++DLG  K++TGI T G+       +V S+ + + N+++ W  Y+       
Sbjct: 286 D----QWLQVDLGSSKEVTGIITQGARNFGSVQFVASYKVAYSNDSANWTEYQDPRTGSS 341

Query: 367 KVFQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQRIALKVELIGC 412
           K+F GN +     +N F  PI+ARYVR++P  WH RIAL++EL+GC
Sbjct: 342 KIFPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIALRLELLGC 387



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 43/131 (32%), Positives = 70/131 (53%), Gaps = 3/131 (2%)

Query: 284 HWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKS 343
           HW P  ARL   G   A   SSN+  P  W++++L  +  +TG+ T G+++   + Y+K+
Sbjct: 100 HWVPELARLNRAGMVNAWTPSSNDDNP--WIQVNLLRRMWVTGVVTQGASRLASHEYLKA 157

Query: 344 FVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQRI 403
           F + +  N  ++      VN + K F GN N      N F  P+ A+YVR+ P + H   
Sbjct: 158 FKVAYSLNGHEFDFIHD-VNKKHKEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTAC 216

Query: 404 ALKVELIGCQI 414
            L+ EL+GC++
Sbjct: 217 TLRFELLGCEL 227


>gi|10518506 coagulation factor VIII isoform b precursor [Homo
           sapiens]
          Length = 216

 Score =  110 bits (275), Expect = 3e-24
 Identities = 62/165 (37%), Positives = 94/165 (56%), Gaps = 13/165 (7%)

Query: 253 NGCSRSLSFEP----DGQIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNH 308
           N CS  L  E     D QI ASS + ++  +     WSP +ARL  QG S A     NN 
Sbjct: 56  NSCSMPLGMESKAISDAQITASSYFTNMFAT-----WSPSKARLHLQGRSNAWRPQVNN- 109

Query: 309 KPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKV 368
            P+EWL++D  +  K+TG+ T G      + YVK F+++   +  +W  +    N + KV
Sbjct: 110 -PKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLF--FQNGKVKV 166

Query: 369 FQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQRIALKVELIGCQ 413
           FQGN +   PV N+  PP++ RY+R+ PQ+W  +IAL++E++GC+
Sbjct: 167 FQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCE 211



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 21/53 (39%), Positives = 32/53 (60%)

Query: 362 VNNEEKVFQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQRIALKVELIGCQI 414
           + +  KVF GN +      N F PPI+ARY+R+ P  +  R  L++EL+GC +
Sbjct: 3   IQDPGKVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDL 55


>gi|66864913 neuropilin 1 isoform c [Homo sapiens]
          Length = 609

 Score =  110 bits (275), Expect = 3e-24
 Identities = 109/438 (24%), Positives = 190/438 (43%), Gaps = 62/438 (14%)

Query: 19  LLALLLAVSAPLRLQAEELGDGCGHLVTYQDSGTMTSKNYPGTYPNHTVCEKTITVPKG- 77
           +LAL+LA +   R       D CG  +  +  G +TS  YP +Y     CE  I  P   
Sbjct: 11  VLALVLAPAGAFR------NDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPY 64

Query: 78  KRLILRLGD-LDIESQTCASDYL-LFTSSSDQ---YGPYCGSMTVPKELLLNTSEVTVRF 132
           +R+++      D+E + C  DY+ +F   ++     G +CG +  P  ++ +   + ++F
Sbjct: 65  QRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIA-PPPVVSSGPFLFIKF 123

Query: 133 ESGSHISGRGFLLTY--------ASSDHPDLITCL------ERASHYLKTEYSKFCPAGC 178
            S     G GF + Y         S ++      +      E+  + L+  Y  F P   
Sbjct: 124 VSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMS 183

Query: 179 RDVAGDISGNMV-DGYRDTSLLCK---AAIHAGI--IADELGGQISVLQRKGISRYEGIL 232
             +    S ++  D      + C+     I  G   +   +G          I    GIL
Sbjct: 184 EIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGIL 243

Query: 233 A-----NGVLSRDGSLSDKRFLFTSNG----CSRSLSFEP----DGQIRASSSWQSVNES 279
           +     +  ++++G  ++   L +S      C  +L  E       QI ASS + +    
Sbjct: 244 SMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYST---- 299

Query: 280 GDQVHWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKKITGIRTTG--STQSNF 337
               +WS  ++RL      W  G+ S     REW+++DLG  + +T + T G  S ++  
Sbjct: 300 ----NWSAERSRLNYPENGWTPGEDSY----REWIQVDLGLLRFVTAVGTQGAISKETKK 351

Query: 338 NFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVQNNFIPPIVARYVRVVPQ 397
            +YVK++ ++  +N   W T K    N+  +FQGN+N  D V   F  P++ R+VR+ P 
Sbjct: 352 KYYVKTYKIDVSSNGEDWITIKE--GNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPA 409

Query: 398 TWHQRIALKVELIGCQIT 415
           TW   I+++ E+ GC+IT
Sbjct: 410 TWETGISMRFEVYGCKIT 427



 Score = 85.9 bits (211), Expect = 9e-17
 Identities = 48/157 (30%), Positives = 79/157 (50%), Gaps = 4/157 (2%)

Query: 270 SSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKKITGIRT 329
           S S  + +  GD+ +W P   RL      WA   + +++   EWL+IDLGE+K + GI  
Sbjct: 443 SDSQITSSNQGDR-NWMPENIRLVTSRSGWALPPAPHSYI-NEWLQIDLGEEKIVRGIII 500

Query: 330 TGSTQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVQNNFIPPIVA 389
            G        +++ F + + NN S WK        + K F+GN+N+  P    F P +  
Sbjct: 501 QGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSFEGNNNYDTPELRTF-PALST 559

Query: 390 RYVRVVPQ-TWHQRIALKVELIGCQITQGNDSLVWRK 425
           R++R+ P+   H  + L++EL+GC++  G   L   K
Sbjct: 560 RFIRIYPERATHGGLGLRMELLGCEVEGGTTVLATEK 596


>gi|66912178 neuropilin 1 isoform b [Homo sapiens]
          Length = 644

 Score =  110 bits (275), Expect = 3e-24
 Identities = 109/438 (24%), Positives = 190/438 (43%), Gaps = 62/438 (14%)

Query: 19  LLALLLAVSAPLRLQAEELGDGCGHLVTYQDSGTMTSKNYPGTYPNHTVCEKTITVPKG- 77
           +LAL+LA +   R       D CG  +  +  G +TS  YP +Y     CE  I  P   
Sbjct: 11  VLALVLAPAGAFR------NDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPY 64

Query: 78  KRLILRLGD-LDIESQTCASDYL-LFTSSSDQ---YGPYCGSMTVPKELLLNTSEVTVRF 132
           +R+++      D+E + C  DY+ +F   ++     G +CG +  P  ++ +   + ++F
Sbjct: 65  QRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIA-PPPVVSSGPFLFIKF 123

Query: 133 ESGSHISGRGFLLTY--------ASSDHPDLITCL------ERASHYLKTEYSKFCPAGC 178
            S     G GF + Y         S ++      +      E+  + L+  Y  F P   
Sbjct: 124 VSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMS 183

Query: 179 RDVAGDISGNMV-DGYRDTSLLCK---AAIHAGI--IADELGGQISVLQRKGISRYEGIL 232
             +    S ++  D      + C+     I  G   +   +G          I    GIL
Sbjct: 184 EIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGIL 243

Query: 233 A-----NGVLSRDGSLSDKRFLFTSNG----CSRSLSFEP----DGQIRASSSWQSVNES 279
           +     +  ++++G  ++   L +S      C  +L  E       QI ASS + +    
Sbjct: 244 SMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYST---- 299

Query: 280 GDQVHWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKKITGIRTTG--STQSNF 337
               +WS  ++RL      W  G+ S     REW+++DLG  + +T + T G  S ++  
Sbjct: 300 ----NWSAERSRLNYPENGWTPGEDSY----REWIQVDLGLLRFVTAVGTQGAISKETKK 351

Query: 338 NFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVQNNFIPPIVARYVRVVPQ 397
            +YVK++ ++  +N   W T K    N+  +FQGN+N  D V   F  P++ R+VR+ P 
Sbjct: 352 KYYVKTYKIDVSSNGEDWITIKE--GNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPA 409

Query: 398 TWHQRIALKVELIGCQIT 415
           TW   I+++ E+ GC+IT
Sbjct: 410 TWETGISMRFEVYGCKIT 427



 Score = 83.2 bits (204), Expect = 6e-16
 Identities = 45/146 (30%), Positives = 76/146 (52%), Gaps = 4/146 (2%)

Query: 270 SSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKKITGIRT 329
           S S  + +  GD+ +W P   RL      WA   + +++   EWL+IDLGE+K + GI  
Sbjct: 443 SDSQITSSNQGDR-NWMPENIRLVTSRSGWALPPAPHSYI-NEWLQIDLGEEKIVRGIII 500

Query: 330 TGSTQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVQNNFIPPIVA 389
            G        +++ F + + NN S WK        + K F+GN+N+  P    F P +  
Sbjct: 501 QGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSFEGNNNYDTPELRTF-PALST 559

Query: 390 RYVRVVPQ-TWHQRIALKVELIGCQI 414
           R++R+ P+   H  + L++EL+GC++
Sbjct: 560 RFIRIYPERATHGGLGLRMELLGCEV 585


>gi|182508169 neuropilin 1 isoform a [Homo sapiens]
          Length = 923

 Score =  110 bits (275), Expect = 3e-24
 Identities = 109/438 (24%), Positives = 190/438 (43%), Gaps = 62/438 (14%)

Query: 19  LLALLLAVSAPLRLQAEELGDGCGHLVTYQDSGTMTSKNYPGTYPNHTVCEKTITVPKG- 77
           +LAL+LA +   R       D CG  +  +  G +TS  YP +Y     CE  I  P   
Sbjct: 11  VLALVLAPAGAFR------NDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPY 64

Query: 78  KRLILRLGD-LDIESQTCASDYL-LFTSSSDQ---YGPYCGSMTVPKELLLNTSEVTVRF 132
           +R+++      D+E + C  DY+ +F   ++     G +CG +  P  ++ +   + ++F
Sbjct: 65  QRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIA-PPPVVSSGPFLFIKF 123

Query: 133 ESGSHISGRGFLLTY--------ASSDHPDLITCL------ERASHYLKTEYSKFCPAGC 178
            S     G GF + Y         S ++      +      E+  + L+  Y  F P   
Sbjct: 124 VSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMS 183

Query: 179 RDVAGDISGNMV-DGYRDTSLLCK---AAIHAGI--IADELGGQISVLQRKGISRYEGIL 232
             +    S ++  D      + C+     I  G   +   +G          I    GIL
Sbjct: 184 EIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGIL 243

Query: 233 A-----NGVLSRDGSLSDKRFLFTSNG----CSRSLSFEP----DGQIRASSSWQSVNES 279
           +     +  ++++G  ++   L +S      C  +L  E       QI ASS + +    
Sbjct: 244 SMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYST---- 299

Query: 280 GDQVHWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKKITGIRTTG--STQSNF 337
               +WS  ++RL      W  G+ S     REW+++DLG  + +T + T G  S ++  
Sbjct: 300 ----NWSAERSRLNYPENGWTPGEDSY----REWIQVDLGLLRFVTAVGTQGAISKETKK 351

Query: 338 NFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVQNNFIPPIVARYVRVVPQ 397
            +YVK++ ++  +N   W T K    N+  +FQGN+N  D V   F  P++ R+VR+ P 
Sbjct: 352 KYYVKTYKIDVSSNGEDWITIKE--GNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPA 409

Query: 398 TWHQRIALKVELIGCQIT 415
           TW   I+++ E+ GC+IT
Sbjct: 410 TWETGISMRFEVYGCKIT 427



 Score = 83.2 bits (204), Expect = 6e-16
 Identities = 45/146 (30%), Positives = 76/146 (52%), Gaps = 4/146 (2%)

Query: 270 SSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKKITGIRT 329
           S S  + +  GD+ +W P   RL      WA   + +++   EWL+IDLGE+K + GI  
Sbjct: 443 SDSQITSSNQGDR-NWMPENIRLVTSRSGWALPPAPHSYI-NEWLQIDLGEEKIVRGIII 500

Query: 330 TGSTQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVQNNFIPPIVA 389
            G        +++ F + + NN S WK        + K F+GN+N+  P    F P +  
Sbjct: 501 QGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSFEGNNNYDTPELRTF-PALST 559

Query: 390 RYVRVVPQ-TWHQRIALKVELIGCQI 414
           R++R+ P+   H  + L++EL+GC++
Sbjct: 560 RFIRIYPERATHGGLGLRMELLGCEV 585


>gi|4503647 coagulation factor VIII isoform a precursor [Homo sapiens]
          Length = 2351

 Score =  110 bits (275), Expect = 3e-24
 Identities = 62/165 (37%), Positives = 94/165 (56%), Gaps = 13/165 (7%)

Query: 253  NGCSRSLSFEP----DGQIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNH 308
            N CS  L  E     D QI ASS + ++  +     WSP +ARL  QG S A     NN 
Sbjct: 2191 NSCSMPLGMESKAISDAQITASSYFTNMFAT-----WSPSKARLHLQGRSNAWRPQVNN- 2244

Query: 309  KPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKV 368
             P+EWL++D  +  K+TG+ T G      + YVK F+++   +  +W  +    N + KV
Sbjct: 2245 -PKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLF--FQNGKVKV 2301

Query: 369  FQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQRIALKVELIGCQ 413
            FQGN +   PV N+  PP++ RY+R+ PQ+W  +IAL++E++GC+
Sbjct: 2302 FQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCE 2346



 Score = 90.1 bits (222), Expect = 5e-18
 Identities = 55/167 (32%), Positives = 83/167 (49%), Gaps = 9/167 (5%)

Query: 248  FLFTSNGCSRSLSFEPDGQIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNN 307
            FL  SN C   L     G IR       +  SG    W+P  ARL   G    S ++ + 
Sbjct: 2033 FLVYSNKCQTPLGMA-SGHIRDFQ----ITASGQYGQWAPKLARLHYSG----SINAWST 2083

Query: 308  HKPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEK 367
             +P  W+++DL     I GI+T G+ Q   + Y+  F++ +  +  KW+TY+G       
Sbjct: 2084 KEPFSWIKVDLLAPMIIHGIKTQGARQKFSSLYISQFIIMYSLDGKKWQTYRGNSTGTLM 2143

Query: 368  VFQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQRIALKVELIGCQI 414
            VF GN +      N F PPI+ARY+R+ P  +  R  L++EL+GC +
Sbjct: 2144 VFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDL 2190


>gi|31317224 EGF-like repeats and discoidin I-like
           domains-containing protein 3 [Homo sapiens]
          Length = 480

 Score =  103 bits (257), Expect = 4e-22
 Identities = 59/166 (35%), Positives = 92/166 (55%), Gaps = 12/166 (7%)

Query: 253 NGCSRSLSFEP----DGQIRASSSWQSVNESGDQVHWSPGQARLQDQGP--SWASGDSSN 306
           +GCS  L  +     D QI ASS ++++N   D   W P +ARL  QG   +W SG +  
Sbjct: 317 SGCSEPLGMKSGHIQDYQITASSIFRTLNM--DMFTWEPRKARLDKQGKVNAWTSGHNDQ 374

Query: 307 NHKPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEE 366
           +    +WL++DL    K+TGI T G+       +V S+ + + N+   W  Y+     ++
Sbjct: 375 S----QWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWTVYQDEKQRKD 430

Query: 367 KVFQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQRIALKVELIGC 412
           KVFQGN +     +N   PPI AR++R++P +W+ RI L+ EL+GC
Sbjct: 431 KVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGC 476



 Score = 96.3 bits (238), Expect = 6e-20
 Identities = 59/171 (34%), Positives = 95/171 (55%), Gaps = 9/171 (5%)

Query: 255 CSRSLSFE----PDGQIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNHKP 310
           CS  L  E     + QI ASS+ +++   G Q  W P  ARL  +G   A   + N+  P
Sbjct: 158 CSGPLGIEGGIISNQQITASSTHRAL--FGLQ-KWYPYYARLNKKGLINAWTAAENDRWP 214

Query: 311 REWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQ 370
             W++I+L  K ++TG+ T G+ +     Y+KS+ + + N+   W  YK    NE+ VF+
Sbjct: 215 --WIQINLQRKMRVTGVITQGAKRIGSPEYIKSYKIAYSNDGKTWAMYKVKGTNEDMVFR 272

Query: 371 GNSNFRDPVQNNFIPPIVARYVRVVPQTWHQRIALKVELIGCQITQGNDSL 421
           GN +   P  N+F PPI A+YVR+ PQ   +   L++EL+GC+++  ++ L
Sbjct: 273 GNIDNNTPYANSFTPPIKAQYVRLYPQVCRRHCTLRMELLGCELSGCSEPL 323


>gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]
          Length = 909

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 54/152 (35%), Positives = 81/152 (53%), Gaps = 15/152 (9%)

Query: 266 QIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKKIT 325
           QI ASS++           W+P Q+RL      W     SN    +E+L++DL     +T
Sbjct: 292 QISASSTYSDGR-------WTPQQSRLHGDDNGWTPNLDSN----KEYLQVDLRFLTMLT 340

Query: 326 GIRTTG--STQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVQNNF 383
            I T G  S ++   +YVKS+ +    N   W  Y+   N+  KVFQ N++  + V N  
Sbjct: 341 AIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNH--KVFQANNDATEVVLNKL 398

Query: 384 IPPIVARYVRVVPQTWHQRIALKVELIGCQIT 415
             P++ R+VR+ PQTWH  IAL++EL GC++T
Sbjct: 399 HAPLLTRFVRIRPQTWHSGIALRLELFGCRVT 430



 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 59/196 (30%), Positives = 90/196 (45%), Gaps = 25/196 (12%)

Query: 264 DGQIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKK 323
           D QI ASS+ + +        WSP  ARL      W            EWL++DLG  K 
Sbjct: 447 DSQISASSTQEYL--------WSPSAARLVSSRSGWFPR-IPQAQPGEEWLQVDLGTPKT 497

Query: 324 ITGIRTTGS------TQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRD 377
           + G+   G+      T      +V+ F +++  N   W+  +     + K+F+GN ++  
Sbjct: 498 VKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDT 557

Query: 378 PVQNNFIPPIVARYVRVVPQTWHQR-IALKVELIGCQITQGNDSLVWRKTSQSTSVSTKK 436
           P    F  PI A+YVRV P+ W    I +++E++GC  T         K +  T   T K
Sbjct: 558 PDIRRF-DPIPAQYVRVYPERWSPAGIGMRLEVLGCDWTDS-------KPTVETLGPTVK 609

Query: 437 EDETITRPIPSEETST 452
            +ET T P P+EE +T
Sbjct: 610 SEET-TTPYPTEEEAT 624



 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 33/113 (29%), Positives = 58/113 (51%), Gaps = 7/113 (6%)

Query: 41  CGHLVTYQDSGTMTSKNYPGTYPNHTVCEKTITVPK-GKRLILRLG-DLDIESQTCASDY 98
           CG  +  +D+G +TS  YP  YP+H  CE  +  P+  ++++L      +IE   C  D+
Sbjct: 28  CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87

Query: 99  LLF----TSSSDQYGPYCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTY 147
           +      + S+D  G +CG++  P  ++ + S + ++F S     G GF L Y
Sbjct: 88  IEIRDGDSESADLLGKHCGNI-APPTIISSGSMLYIKFTSDYARQGAGFSLRY 139



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 30/109 (27%), Positives = 47/109 (43%), Gaps = 12/109 (11%)

Query: 50  SGTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGDLDIESQ-------TCASDYLLFT 102
           +GT+ S  +P  YP++  C  TI       +IL+    D+E          C  D+L   
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIW 216

Query: 103 SSSDQYGP----YCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTY 147
                 GP    YCG+ T P EL  +T  +++ F +   ++  GF   Y
Sbjct: 217 DGIPHVGPLIGKYCGTKT-PSELRSSTGILSLTFHTDMAVAKDGFSARY 264


>gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens]
          Length = 901

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 54/152 (35%), Positives = 81/152 (53%), Gaps = 15/152 (9%)

Query: 266 QIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKKIT 325
           QI ASS++           W+P Q+RL      W     SN    +E+L++DL     +T
Sbjct: 292 QISASSTYSDGR-------WTPQQSRLHGDDNGWTPNLDSN----KEYLQVDLRFLTMLT 340

Query: 326 GIRTTG--STQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVQNNF 383
            I T G  S ++   +YVKS+ +    N   W  Y+   N+  KVFQ N++  + V N  
Sbjct: 341 AIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNH--KVFQANNDATEVVLNKL 398

Query: 384 IPPIVARYVRVVPQTWHQRIALKVELIGCQIT 415
             P++ R+VR+ PQTWH  IAL++EL GC++T
Sbjct: 399 HAPLLTRFVRIRPQTWHSGIALRLELFGCRVT 430



 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 59/196 (30%), Positives = 90/196 (45%), Gaps = 25/196 (12%)

Query: 264 DGQIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKK 323
           D QI ASS+ + +        WSP  ARL      W            EWL++DLG  K 
Sbjct: 447 DSQISASSTQEYL--------WSPSAARLVSSRSGWFPR-IPQAQPGEEWLQVDLGTPKT 497

Query: 324 ITGIRTTGS------TQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRD 377
           + G+   G+      T      +V+ F +++  N   W+  +     + K+F+GN ++  
Sbjct: 498 VKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDT 557

Query: 378 PVQNNFIPPIVARYVRVVPQTWHQR-IALKVELIGCQITQGNDSLVWRKTSQSTSVSTKK 436
           P    F  PI A+YVRV P+ W    I +++E++GC  T         K +  T   T K
Sbjct: 558 PDIRRF-DPIPAQYVRVYPERWSPAGIGMRLEVLGCDWTDS-------KPTVETLGPTVK 609

Query: 437 EDETITRPIPSEETST 452
            +ET T P P+EE +T
Sbjct: 610 SEET-TTPYPTEEEAT 624



 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 33/113 (29%), Positives = 58/113 (51%), Gaps = 7/113 (6%)

Query: 41  CGHLVTYQDSGTMTSKNYPGTYPNHTVCEKTITVPK-GKRLILRLG-DLDIESQTCASDY 98
           CG  +  +D+G +TS  YP  YP+H  CE  +  P+  ++++L      +IE   C  D+
Sbjct: 28  CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87

Query: 99  LLF----TSSSDQYGPYCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTY 147
           +      + S+D  G +CG++  P  ++ + S + ++F S     G GF L Y
Sbjct: 88  IEIRDGDSESADLLGKHCGNI-APPTIISSGSMLYIKFTSDYARQGAGFSLRY 139



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 30/109 (27%), Positives = 47/109 (43%), Gaps = 12/109 (11%)

Query: 50  SGTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGDLDIESQ-------TCASDYLLFT 102
           +GT+ S  +P  YP++  C  TI       +IL+    D+E          C  D+L   
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIW 216

Query: 103 SSSDQYGP----YCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTY 147
                 GP    YCG+ T P EL  +T  +++ F +   ++  GF   Y
Sbjct: 217 DGIPHVGPLIGKYCGTKT-PSELRSSTGILSLTFHTDMAVAKDGFSARY 264


>gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens]
          Length = 931

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 54/152 (35%), Positives = 81/152 (53%), Gaps = 15/152 (9%)

Query: 266 QIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKKIT 325
           QI ASS++           W+P Q+RL      W     SN    +E+L++DL     +T
Sbjct: 292 QISASSTYSDGR-------WTPQQSRLHGDDNGWTPNLDSN----KEYLQVDLRFLTMLT 340

Query: 326 GIRTTG--STQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVQNNF 383
            I T G  S ++   +YVKS+ +    N   W  Y+   N+  KVFQ N++  + V N  
Sbjct: 341 AIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNH--KVFQANNDATEVVLNKL 398

Query: 384 IPPIVARYVRVVPQTWHQRIALKVELIGCQIT 415
             P++ R+VR+ PQTWH  IAL++EL GC++T
Sbjct: 399 HAPLLTRFVRIRPQTWHSGIALRLELFGCRVT 430



 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 59/196 (30%), Positives = 90/196 (45%), Gaps = 25/196 (12%)

Query: 264 DGQIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKK 323
           D QI ASS+ + +        WSP  ARL      W            EWL++DLG  K 
Sbjct: 447 DSQISASSTQEYL--------WSPSAARLVSSRSGWFPR-IPQAQPGEEWLQVDLGTPKT 497

Query: 324 ITGIRTTGS------TQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRD 377
           + G+   G+      T      +V+ F +++  N   W+  +     + K+F+GN ++  
Sbjct: 498 VKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDT 557

Query: 378 PVQNNFIPPIVARYVRVVPQTWHQR-IALKVELIGCQITQGNDSLVWRKTSQSTSVSTKK 436
           P    F  PI A+YVRV P+ W    I +++E++GC  T         K +  T   T K
Sbjct: 558 PDIRRF-DPIPAQYVRVYPERWSPAGIGMRLEVLGCDWTDS-------KPTVETLGPTVK 609

Query: 437 EDETITRPIPSEETST 452
            +ET T P P+EE +T
Sbjct: 610 SEET-TTPYPTEEEAT 624



 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 33/113 (29%), Positives = 58/113 (51%), Gaps = 7/113 (6%)

Query: 41  CGHLVTYQDSGTMTSKNYPGTYPNHTVCEKTITVPK-GKRLILRLG-DLDIESQTCASDY 98
           CG  +  +D+G +TS  YP  YP+H  CE  +  P+  ++++L      +IE   C  D+
Sbjct: 28  CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87

Query: 99  LLF----TSSSDQYGPYCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTY 147
           +      + S+D  G +CG++  P  ++ + S + ++F S     G GF L Y
Sbjct: 88  IEIRDGDSESADLLGKHCGNI-APPTIISSGSMLYIKFTSDYARQGAGFSLRY 139



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 30/109 (27%), Positives = 47/109 (43%), Gaps = 12/109 (11%)

Query: 50  SGTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGDLDIESQ-------TCASDYLLFT 102
           +GT+ S  +P  YP++  C  TI       +IL+    D+E          C  D+L   
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIW 216

Query: 103 SSSDQYGP----YCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTY 147
                 GP    YCG+ T P EL  +T  +++ F +   ++  GF   Y
Sbjct: 217 DGIPHVGPLIGKYCGTKT-PSELRSSTGILSLTFHTDMAVAKDGFSARY 264


>gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens]
          Length = 555

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 54/152 (35%), Positives = 81/152 (53%), Gaps = 15/152 (9%)

Query: 266 QIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKKIT 325
           QI ASS++           W+P Q+RL      W     SN    +E+L++DL     +T
Sbjct: 292 QISASSTYSDGR-------WTPQQSRLHGDDNGWTPNLDSN----KEYLQVDLRFLTMLT 340

Query: 326 GIRTTG--STQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVQNNF 383
            I T G  S ++   +YVKS+ +    N   W  Y+   N+  KVFQ N++  + V N  
Sbjct: 341 AIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNH--KVFQANNDATEVVLNKL 398

Query: 384 IPPIVARYVRVVPQTWHQRIALKVELIGCQIT 415
             P++ R+VR+ PQTWH  IAL++EL GC++T
Sbjct: 399 HAPLLTRFVRIRPQTWHSGIALRLELFGCRVT 430



 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 33/113 (29%), Positives = 58/113 (51%), Gaps = 7/113 (6%)

Query: 41  CGHLVTYQDSGTMTSKNYPGTYPNHTVCEKTITVPK-GKRLILRLG-DLDIESQTCASDY 98
           CG  +  +D+G +TS  YP  YP+H  CE  +  P+  ++++L      +IE   C  D+
Sbjct: 28  CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87

Query: 99  LLF----TSSSDQYGPYCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTY 147
           +      + S+D  G +CG++  P  ++ + S + ++F S     G GF L Y
Sbjct: 88  IEIRDGDSESADLLGKHCGNI-APPTIISSGSMLYIKFTSDYARQGAGFSLRY 139



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 30/109 (27%), Positives = 47/109 (43%), Gaps = 12/109 (11%)

Query: 50  SGTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGDLDIESQ-------TCASDYLLFT 102
           +GT+ S  +P  YP++  C  TI       +IL+    D+E          C  D+L   
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIW 216

Query: 103 SSSDQYGP----YCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTY 147
                 GP    YCG+ T P EL  +T  +++ F +   ++  GF   Y
Sbjct: 217 DGIPHVGPLIGKYCGTKT-PSELRSSTGILSLTFHTDMAVAKDGFSARY 264



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 15/111 (13%)

Query: 264 DGQIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKK 323
           D QI ASS+ + +        WSP  ARL      W            EWL++DLG  K 
Sbjct: 447 DSQISASSTQEYL--------WSPSAARLVSSRSGWFPR-IPQAQPGEEWLQVDLGTPKT 497

Query: 324 ITGIRTTGS------TQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKV 368
           + G+   G+      T      +V+ F +++  N   W+  +     + KV
Sbjct: 498 VKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKV 548


>gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens]
          Length = 906

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 54/152 (35%), Positives = 81/152 (53%), Gaps = 15/152 (9%)

Query: 266 QIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKKIT 325
           QI ASS++           W+P Q+RL      W     SN    +E+L++DL     +T
Sbjct: 292 QISASSTYSDGR-------WTPQQSRLHGDDNGWTPNLDSN----KEYLQVDLRFLTMLT 340

Query: 326 GIRTTG--STQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVQNNF 383
            I T G  S ++   +YVKS+ +    N   W  Y+   N+  KVFQ N++  + V N  
Sbjct: 341 AIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNH--KVFQANNDATEVVLNKL 398

Query: 384 IPPIVARYVRVVPQTWHQRIALKVELIGCQIT 415
             P++ R+VR+ PQTWH  IAL++EL GC++T
Sbjct: 399 HAPLLTRFVRIRPQTWHSGIALRLELFGCRVT 430



 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 59/196 (30%), Positives = 90/196 (45%), Gaps = 25/196 (12%)

Query: 264 DGQIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKK 323
           D QI ASS+ + +        WSP  ARL      W            EWL++DLG  K 
Sbjct: 447 DSQISASSTQEYL--------WSPSAARLVSSRSGWFPR-IPQAQPGEEWLQVDLGTPKT 497

Query: 324 ITGIRTTGS------TQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRD 377
           + G+   G+      T      +V+ F +++  N   W+  +     + K+F+GN ++  
Sbjct: 498 VKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDT 557

Query: 378 PVQNNFIPPIVARYVRVVPQTWHQR-IALKVELIGCQITQGNDSLVWRKTSQSTSVSTKK 436
           P    F  PI A+YVRV P+ W    I +++E++GC  T         K +  T   T K
Sbjct: 558 PDIRRF-DPIPAQYVRVYPERWSPAGIGMRLEVLGCDWTDS-------KPTVETLGPTVK 609

Query: 437 EDETITRPIPSEETST 452
            +ET T P P+EE +T
Sbjct: 610 SEET-TTPYPTEEEAT 624



 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 33/113 (29%), Positives = 58/113 (51%), Gaps = 7/113 (6%)

Query: 41  CGHLVTYQDSGTMTSKNYPGTYPNHTVCEKTITVPK-GKRLILRLG-DLDIESQTCASDY 98
           CG  +  +D+G +TS  YP  YP+H  CE  +  P+  ++++L      +IE   C  D+
Sbjct: 28  CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87

Query: 99  LLF----TSSSDQYGPYCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTY 147
           +      + S+D  G +CG++  P  ++ + S + ++F S     G GF L Y
Sbjct: 88  IEIRDGDSESADLLGKHCGNI-APPTIISSGSMLYIKFTSDYARQGAGFSLRY 139



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 30/109 (27%), Positives = 47/109 (43%), Gaps = 12/109 (11%)

Query: 50  SGTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGDLDIESQ-------TCASDYLLFT 102
           +GT+ S  +P  YP++  C  TI       +IL+    D+E          C  D+L   
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIW 216

Query: 103 SSSDQYGP----YCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTY 147
                 GP    YCG+ T P EL  +T  +++ F +   ++  GF   Y
Sbjct: 217 DGIPHVGPLIGKYCGTKT-PSELRSSTGILSLTFHTDMAVAKDGFSARY 264


>gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens]
          Length = 926

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 54/152 (35%), Positives = 81/152 (53%), Gaps = 15/152 (9%)

Query: 266 QIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKKIT 325
           QI ASS++           W+P Q+RL      W     SN    +E+L++DL     +T
Sbjct: 292 QISASSTYSDGR-------WTPQQSRLHGDDNGWTPNLDSN----KEYLQVDLRFLTMLT 340

Query: 326 GIRTTG--STQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVQNNF 383
            I T G  S ++   +YVKS+ +    N   W  Y+   N+  KVFQ N++  + V N  
Sbjct: 341 AIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNH--KVFQANNDATEVVLNKL 398

Query: 384 IPPIVARYVRVVPQTWHQRIALKVELIGCQIT 415
             P++ R+VR+ PQTWH  IAL++EL GC++T
Sbjct: 399 HAPLLTRFVRIRPQTWHSGIALRLELFGCRVT 430



 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 59/196 (30%), Positives = 90/196 (45%), Gaps = 25/196 (12%)

Query: 264 DGQIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKK 323
           D QI ASS+ + +        WSP  ARL      W            EWL++DLG  K 
Sbjct: 447 DSQISASSTQEYL--------WSPSAARLVSSRSGWFPR-IPQAQPGEEWLQVDLGTPKT 497

Query: 324 ITGIRTTGS------TQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRD 377
           + G+   G+      T      +V+ F +++  N   W+  +     + K+F+GN ++  
Sbjct: 498 VKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDT 557

Query: 378 PVQNNFIPPIVARYVRVVPQTWHQR-IALKVELIGCQITQGNDSLVWRKTSQSTSVSTKK 436
           P    F  PI A+YVRV P+ W    I +++E++GC  T         K +  T   T K
Sbjct: 558 PDIRRF-DPIPAQYVRVYPERWSPAGIGMRLEVLGCDWTDS-------KPTVETLGPTVK 609

Query: 437 EDETITRPIPSEETST 452
            +ET T P P+EE +T
Sbjct: 610 SEET-TTPYPTEEEAT 624



 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 33/113 (29%), Positives = 58/113 (51%), Gaps = 7/113 (6%)

Query: 41  CGHLVTYQDSGTMTSKNYPGTYPNHTVCEKTITVPK-GKRLILRLG-DLDIESQTCASDY 98
           CG  +  +D+G +TS  YP  YP+H  CE  +  P+  ++++L      +IE   C  D+
Sbjct: 28  CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87

Query: 99  LLF----TSSSDQYGPYCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTY 147
           +      + S+D  G +CG++  P  ++ + S + ++F S     G GF L Y
Sbjct: 88  IEIRDGDSESADLLGKHCGNI-APPTIISSGSMLYIKFTSDYARQGAGFSLRY 139



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 30/109 (27%), Positives = 47/109 (43%), Gaps = 12/109 (11%)

Query: 50  SGTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGDLDIESQ-------TCASDYLLFT 102
           +GT+ S  +P  YP++  C  TI       +IL+    D+E          C  D+L   
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIW 216

Query: 103 SSSDQYGP----YCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTY 147
                 GP    YCG+ T P EL  +T  +++ F +   ++  GF   Y
Sbjct: 217 DGIPHVGPLIGKYCGTKT-PSELRSSTGILSLTFHTDMAVAKDGFSARY 264


>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
           sapiens]
          Length = 1158

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 55/214 (25%), Positives = 95/214 (44%), Gaps = 22/214 (10%)

Query: 264 DGQIRASSSWQ-SVNESGDQVHWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKK 322
           D QIRASS  +  +     +++   G         +W + D +      +W+E+D     
Sbjct: 397 DNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAEDDART----QWIEVDTRRTT 452

Query: 323 KITGIRTTGSTQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVQNN 382
           + TG+ T G   S  + +V +F + F N++  W  Y      EE  F GN +   PV + 
Sbjct: 453 RFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTWVMYTN--GYEEMTFHGNVDKDTPVLSE 510

Query: 383 FIPPIVARYVRVVPQTWHQRIALKVELIGCQITQ-----------GNDSLVWR----KTS 427
              P+VAR++R+ P TW+  + +++E++GC +               D L +R    K  
Sbjct: 511 LPEPVVARFIRIYPLTWNGSLCMRLEVLGCSVAPVYSYYAQNEVVATDDLDFRHHSYKDM 570

Query: 428 QSTSVSTKKEDETITRPIPSEETSTGINITTVAI 461
           +       +E  TITR     ++S G+ I  + I
Sbjct: 571 RQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEI 604


>gi|10835083 X-linked juvenile retinoschisis protein precursor [Homo
           sapiens]
          Length = 224

 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 56/152 (36%), Positives = 80/152 (52%), Gaps = 12/152 (7%)

Query: 263 PDGQIRASSSWQSVNESGDQVHWSPGQARLQDQG--PSWASGDSSNNHKPREWLEIDLGE 320
           PD QI  S+  Q V   G    W+  +ARL  QG   +W S    ++    +WL+IDL E
Sbjct: 78  PD-QITCSNPEQYV---GWYSSWTANKARLNSQGFGCAWLSKFQDSS----QWLQIDLKE 129

Query: 321 KKKITGIRTTGSTQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVQ 380
            K I+GI T G    +  +  K  V    +    W  YK    N  +VF GNS+    VQ
Sbjct: 130 IKVISGILTQGRCDID-EWMTKYSVQYRTDERLNWIYYKDQTGNN-RVFYGNSDRTSTVQ 187

Query: 381 NNFIPPIVARYVRVVPQTWHQRIALKVELIGC 412
           N   PPI++R++R++P  WH RIA+++EL+ C
Sbjct: 188 NLLRPPIISRFIRLIPLGWHVRIAIRMELLEC 219


>gi|7662350 cell recognition molecule Caspr2 precursor [Homo
           sapiens]
          Length = 1331

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 48/146 (32%), Positives = 77/146 (52%), Gaps = 13/146 (8%)

Query: 269 ASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKKITGIR 328
           A SS  S++ S     +SPG A++  +G +     S ++H   +WL++D G +K+I+ I 
Sbjct: 47  AFSSSSSISGS-----YSPGYAKINKRGGAGGWSPSDSDHY--QWLQVDFGNRKQISAIA 99

Query: 329 TTGSTQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVQNNFIPPIV 388
           T G   S+   +V  + M + +    WK Y    +     F GN N    V++    PI+
Sbjct: 100 TQGRYSSSD--WVTQYRMLYSDTGRNWKPYHQ--DGNIWAFPGNINSDGVVRHELQHPII 155

Query: 389 ARYVRVVPQTWH--QRIALKVELIGC 412
           ARYVR+VP  W+   RI L++E+ GC
Sbjct: 156 ARYVRIVPLDWNGEGRIGLRIEVYGC 181


>gi|167830477 milk fat globule-EGF factor 8 protein isoform b [Homo
           sapiens]
          Length = 335

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 43/131 (32%), Positives = 70/131 (53%), Gaps = 3/131 (2%)

Query: 284 HWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKS 343
           HW P  ARL   G   A   SSN+  P  W++++L  +  +TG+ T G+++   + Y+K+
Sbjct: 100 HWVPELARLNRAGMVNAWTPSSNDDNP--WIQVNLLRRMWVTGVVTQGASRLASHEYLKA 157

Query: 344 FVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQRI 403
           F + +  N  ++      VN + K F GN N      N F  P+ A+YVR+ P + H   
Sbjct: 158 FKVAYSLNGHEFDFIHD-VNKKHKEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTAC 216

Query: 404 ALKVELIGCQI 414
            L+ EL+GC++
Sbjct: 217 TLRFELLGCEL 227



 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 48/164 (29%), Positives = 66/164 (40%), Gaps = 60/164 (36%)

Query: 253 NGCSRSLSFE----PDGQIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNH 308
           NGC+  L  +    PD QI ASSS+++         W+P  ARL  QG            
Sbjct: 228 NGCANPLGLKNNSIPDKQITASSSYKTWGLH--LFSWNPSYARLDKQG------------ 273

Query: 309 KPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKV 368
                                      NFN +V          N +W           ++
Sbjct: 274 ---------------------------NFNAWVAG-----SYGNDQWL----------QI 291

Query: 369 FQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQRIALKVELIGC 412
           F GN +     +N F  PI+ARYVR++P  WH RIAL++EL+GC
Sbjct: 292 FPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIALRLELLGC 335


>gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo
           sapiens]
          Length = 756

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 36/124 (29%), Positives = 66/124 (53%), Gaps = 8/124 (6%)

Query: 298 SWASGDSSNNHKPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSFVMNFKNNNSKWKT 357
           +W +G     +  ++W+E+D     + TG+ T G      + +V S+ +   N++  W T
Sbjct: 183 AWCAG----RNDLQQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVT 238

Query: 358 YKGIVNNEEKVFQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQR--IALKVELIGCQIT 415
            K    + + +F+GNS    PV N    P+VARY+R+ PQ+W     I +++E++GC + 
Sbjct: 239 VKN--GSGDMIFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLP 296

Query: 416 QGND 419
             N+
Sbjct: 297 DPNN 300


>gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo
           sapiens]
          Length = 1235

 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 49/155 (31%), Positives = 78/155 (50%), Gaps = 18/155 (11%)

Query: 287 PGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSFVM 346
           PG ARL  +    A G S       +WL+IDLGE+ ++T + T G   S  + +V S+++
Sbjct: 31  PGFARLNRR--DGAGGWSPLVSNKYQWLQIDLGERMEVTAVATQGGYGS--SNWVTSYLL 86

Query: 347 NFKNNNSKWKTYKGIVNNEEKV--FQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQ--R 402
            F ++   WK Y+     E+ +  F GN+N    V     P I AR++R +P  W+   R
Sbjct: 87  MFSDSGWNWKQYR----QEDSIWGFSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGR 142

Query: 403 IALKVELIGCQI------TQGNDSLVWRKTSQSTS 431
           I +++E+ GC          G  SL++R   +S S
Sbjct: 143 IGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLS 177


>gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo
           sapiens]
          Length = 1308

 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 49/155 (31%), Positives = 78/155 (50%), Gaps = 18/155 (11%)

Query: 287 PGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSFVM 346
           PG ARL  +    A G S       +WL+IDLGE+ ++T + T G   S  + +V S+++
Sbjct: 56  PGFARLNRR--DGAGGWSPLVSNKYQWLQIDLGERMEVTAVATQGGYGS--SNWVTSYLL 111

Query: 347 NFKNNNSKWKTYKGIVNNEEKV--FQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQ--R 402
            F ++   WK Y+     E+ +  F GN+N    V     P I AR++R +P  W+   R
Sbjct: 112 MFSDSGWNWKQYR----QEDSIWGFSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGR 167

Query: 403 IALKVELIGCQI------TQGNDSLVWRKTSQSTS 431
           I +++E+ GC          G  SL++R   +S S
Sbjct: 168 IGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLS 202


>gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2
           [Homo sapiens]
          Length = 1207

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 43/132 (32%), Positives = 69/132 (52%), Gaps = 16/132 (12%)

Query: 287 PGQARL--QDQGPSWASGDSSNNHKPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSF 344
           PG +RL  +D    W    S+      +WL+IDLGE+ ++T + T G   S+   +V S+
Sbjct: 56  PGFSRLNRRDGAGGWTPLVSNKY----QWLQIDLGERMEVTAVATQGGYGSSD--WVTSY 109

Query: 345 VMNFKNNNSKWKTYKGIVNNEEKV--FQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQ- 401
           ++ F +    WK Y+     EE +  F GN+N    V     PP  AR++R +P  W+  
Sbjct: 110 LLMFSDGGRNWKQYR----REESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPR 165

Query: 402 -RIALKVELIGC 412
            RI +++E+ GC
Sbjct: 166 GRIGMRIEVYGC 177


>gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1
           [Homo sapiens]
          Length = 1288

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 43/132 (32%), Positives = 69/132 (52%), Gaps = 16/132 (12%)

Query: 287 PGQARL--QDQGPSWASGDSSNNHKPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSF 344
           PG +RL  +D    W    S+      +WL+IDLGE+ ++T + T G   S+   +V S+
Sbjct: 56  PGFSRLNRRDGAGGWTPLVSNKY----QWLQIDLGERMEVTAVATQGGYGSSD--WVTSY 109

Query: 345 VMNFKNNNSKWKTYKGIVNNEEKV--FQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQ- 401
           ++ F +    WK Y+     EE +  F GN+N    V     PP  AR++R +P  W+  
Sbjct: 110 LLMFSDGGRNWKQYR----REESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPR 165

Query: 402 -RIALKVELIGC 412
            RI +++E+ GC
Sbjct: 166 GRIGMRIEVYGC 177


>gi|239743729 PREDICTED: similar to contactin associated
           protein-like 3B [Homo sapiens]
          Length = 380

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 43/132 (32%), Positives = 69/132 (52%), Gaps = 16/132 (12%)

Query: 287 PGQARL--QDQGPSWASGDSSNNHKPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSF 344
           PG +RL  +D    W    S+      +WL+IDLGE+ ++T + T G   S+   +V S+
Sbjct: 56  PGFSRLNRRDGAGGWTPLVSNKY----QWLQIDLGERMEVTAVATQGGYGSSD--WVTSY 109

Query: 345 VMNFKNNNSKWKTYKGIVNNEEKV--FQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQ- 401
           ++ F +    WK Y+     EE +  F GN+N    V     PP  AR++R +P  W+  
Sbjct: 110 LLMFSDGGRNWKQYR----REESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPR 165

Query: 402 -RIALKVELIGC 412
            RI +++E+ GC
Sbjct: 166 GRIGMRIEVYGC 177


>gi|47519929 cell recognition molecule CASPR3 [Homo sapiens]
          Length = 1288

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 43/132 (32%), Positives = 69/132 (52%), Gaps = 16/132 (12%)

Query: 287 PGQARL--QDQGPSWASGDSSNNHKPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSF 344
           PG +RL  +D    W    S+      +WL+IDLGE+ ++T + T G   S+   +V S+
Sbjct: 56  PGFSRLNRRDGAGGWTPLVSNKY----QWLQIDLGERMEVTAVATQGGYGSSD--WVTSY 109

Query: 345 VMNFKNNNSKWKTYKGIVNNEEKV--FQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQ- 401
           ++ F +    WK Y+     EE +  F GN+N    V     PP  AR++R +P  W+  
Sbjct: 110 LLMFSDGGRNWKQYR----REESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPR 165

Query: 402 -RIALKVELIGC 412
            RI +++E+ GC
Sbjct: 166 GRIGMRIEVYGC 177


>gi|18640734 contactin associated protein-like 5 [Homo sapiens]
          Length = 1306

 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 52/184 (28%), Positives = 85/184 (46%), Gaps = 27/184 (14%)

Query: 251 TSNGCSRSLSFEPDGQIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNHKP 310
           T+  C   L+        +SSS  +   S  Q++W  G          W+  DS+     
Sbjct: 26  TNYNCDDPLASLLSPMAFSSSSDLTGTHSPAQLNWRVGTG-------GWSPADSN----A 74

Query: 311 REWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKV-- 368
           ++WL++DLG + +IT + T G   S  + +V S+ + F +    WK YK     E+ +  
Sbjct: 75  QQWLQMDLGNRVEITAVATQGRYGS--SDWVTSYSLMFSDTGRNWKQYK----QEDSIWT 128

Query: 369 FQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQ--RIALKVELIGCQIT------QGNDS 420
           F GN N    V +  +  + AR+VR VP  W+   +I ++VE+ GC          G  S
Sbjct: 129 FAGNMNADSVVHHKLLHSVRARFVRFVPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRSS 188

Query: 421 LVWR 424
           L++R
Sbjct: 189 LLYR 192


>gi|126091152 cubilin [Homo sapiens]
          Length = 3623

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 38/115 (33%), Positives = 58/115 (50%), Gaps = 6/115 (5%)

Query: 40   GCGHLVTYQDSGTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGDLDIESQ-TCASDY 98
            GCG  + Y D G+ TS  YPGTYPN+T CE  +  P G+ + +    + I+    C  +Y
Sbjct: 3510 GCGGTL-YGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNY 3568

Query: 99   LLF----TSSSDQYGPYCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTYAS 149
            L       +SS   GPYCG  T     + ++++V ++F +        F LT+ S
Sbjct: 3569 LTLYDGPNASSPSSGPYCGGDTSIAPFVASSNQVFIKFHADYARRPSAFRLTWDS 3623



 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 35/104 (33%), Positives = 51/104 (49%), Gaps = 6/104 (5%)

Query: 49   DSGTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGDLDIESQ-TCASDYLLF----TS 103
            DSG +TS NYP  Y + T C   +  P+G  + L   D DIE   TCA D +      + 
Sbjct: 2696 DSGVITSPNYPNAYDSLTHCSSLLEAPQGHTITLTFSDFDIEPHTTCAWDSVTVRNGGSP 2755

Query: 104  SSDQYGPYCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTY 147
             S   G YCG+   P+ +   ++++ V F S   + G GF  T+
Sbjct: 2756 ESPIIGQYCGNSN-PRTIQSGSNQLVVTFNSDHSLQGGGFYATW 2798



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 44/129 (34%), Positives = 67/129 (51%), Gaps = 12/129 (9%)

Query: 31   RLQAEELGDGCGHLVTYQDS-GTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGDLDI 89
            RL+ E   + CG     Q S GT TS NYP   P+  +CE  IT P+G+R+ L   +L +
Sbjct: 2442 RLRFESSMEECGG--DLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRL 2499

Query: 90   ESQ-TCASDYLL----FTSSSDQYGPYCGSMTVPKELLL--NTSEVTVRFESGSHISGRG 142
             +  +C +++++      S+S Q    C S+ V  E+    NT +V + F  GS   G G
Sbjct: 2500 ATHPSCNNEHVIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKV-IFFTDGSRPYG-G 2557

Query: 143  FLLTYASSD 151
            F  +Y SS+
Sbjct: 2558 FTASYTSSE 2566



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 32/105 (30%), Positives = 52/105 (49%), Gaps = 2/105 (1%)

Query: 40   GCGHLVTYQDSGTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGDLDIESQ-TCASDY 98
            GCG +     SG + S NYP  Y ++T C   I V +  R++L   D D+E Q +C   Y
Sbjct: 1509 GCGGIFQ-APSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEPQDSCIMAY 1567

Query: 99   LLFTSSSDQYGPYCGSMTVPKELLLNTSEVTVRFESGSHISGRGF 143
               +S+  +    CG   +   ++ + + + +RF+SG     RGF
Sbjct: 1568 DGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGF 1612



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 34/105 (32%), Positives = 53/105 (50%), Gaps = 6/105 (5%)

Query: 51   GTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGDLDIE-SQTCASDYLLF----TSSS 105
            G + S  +P  Y N   C  T+T P+   + L    L IE S  C +D+L       S+S
Sbjct: 3404 GNLRSPGWPDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFLEVRNGSNSNS 3463

Query: 106  DQYGPYCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTYASS 150
               G YCG++ +P  +    +E+ +RF+S S  S RG+ + + SS
Sbjct: 3464 PLLGKYCGTL-LPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSS 3507



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 46/159 (28%), Positives = 67/159 (42%), Gaps = 20/159 (12%)

Query: 11   LARAAGRGLLALLLAVSAP---LRLQA----------EELGDGCGHLVTYQDSGTMTSKN 57
            LAR  GR  LA  +  S     LR Q+           +    CG  +      T++S  
Sbjct: 1577 LARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQFRQACGGHILTSSFDTVSSPR 1636

Query: 58   YPGTYPNHTVCEKTITV-PKGKRLILRLGDLDIE-SQTCASDYLLFTSSSDQYGP----Y 111
            +P  YPN+  C   I   P    + L     ++E S TCA D++       +  P    Y
Sbjct: 1637 FPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDFVEILDGGHEDAPLRGRY 1696

Query: 112  CGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTYASS 150
            CG+  +P  +   +S +T+RF S S IS  GF  T  +S
Sbjct: 1697 CGT-DMPHPITSFSSALTLRFVSDSSISAGGFHTTVTAS 1734



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 35/120 (29%), Positives = 57/120 (47%), Gaps = 7/120 (5%)

Query: 31   RLQAEELGDGCGHLVTYQDSGTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGDLDIE 90
            +  AE+L   CG ++T + +GT+ S  +P  YP+   C   I V     + L      +E
Sbjct: 924  KFSAEDLA--CGEILT-ESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLE 980

Query: 91   -SQTCASDYL--LFTSSSDQYGPYCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTY 147
                C +DYL    T S    G YCG  ++P  L  + + + + F + S ++  GFL+ Y
Sbjct: 981  FHYNCTNDYLEVYDTDSETSLGRYCGK-SIPPSLTSSGNSLMLVFVTDSDLAYEGFLINY 1039



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 37/119 (31%), Positives = 57/119 (47%), Gaps = 8/119 (6%)

Query: 41   CGHLVTYQDSGTMTSKNYP-GTYPNHTVCEKTITVPKGKRLILRLGDLD-IESQTCASDY 98
            CG +  +  SG +TS  Y    YPN   C  TITV   K + L+  D D + S +C+ DY
Sbjct: 3037 CGGVFNFS-SGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPSTSCSHDY 3095

Query: 99   LLF----TSSSDQYGPYCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTYASSDHP 153
            L       +S    G +CGS   P     N S + V F++ S  + +G+ +++  +  P
Sbjct: 3096 LAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLV-FKTDSFQTAKGWKMSFRQTLGP 3153



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 39/140 (27%), Positives = 62/140 (44%), Gaps = 17/140 (12%)

Query: 30   LRLQAEELGDGCGHLVTYQD----------SGTMTSKNYPGTYPNHTVCEKTITVPKGKR 79
            +R  ++  G G G   T+             G + S  +P  YP+++  + T+ V     
Sbjct: 1830 VRFISDGSGSGTGFQATFMKIFGNDNIVGTHGKVASPFWPENYPHNSNYQWTVNVNASHV 1889

Query: 80   LILRLGDLDIES-QTCASDYLLFTSSSDQY----GPYCGSMTVPKELLLNTSEVTVRFES 134
            +  R+ ++DIE  Q C  D L        +    G YCG+ T  +      + +T  F S
Sbjct: 1890 VHGRILEMDIEEIQNCYYDKLRIYDGPSIHARLIGAYCGTQT--ESFSSTGNSLTFHFYS 1947

Query: 135  GSHISGRGFLLTYASSDHPD 154
             S ISG+GFLL + + D PD
Sbjct: 1948 DSSISGKGFLLEWFAVDAPD 1967



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 49/184 (26%), Positives = 68/184 (36%), Gaps = 25/184 (13%)

Query: 11  LARAAGRGLLALLLAVSAPL--RLQAEELGDGCGHLVTYQDS------------GTMTSK 56
           L R  G  L   LL+    L   L +E L +G G  V ++              G++ S 
Sbjct: 545 LGRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQPECGGILTGPYGSIKSP 604

Query: 57  NYPGTYPNHTVCEKTITVPKGKRLILRLGDLDIESQT-CASDYLLFTSS----SDQYGPY 111
            YPG YP    C   +       +    G L +E    C  DYL             G +
Sbjct: 605 GYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDYLEIRDGPLYQDPLLGKF 664

Query: 112 CGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTYASSDHPDLITCLERASHYLKTEYS 171
           C + +VP  L        + F S S IS +GF +TY +S  P  + C     +Y   E  
Sbjct: 665 CTTFSVPP-LQTTGPFARIHFHSDSQISDQGFHITYLTS--PSDLRC---GGNYTDPEGE 718

Query: 172 KFCP 175
            F P
Sbjct: 719 LFLP 722



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 36/127 (28%), Positives = 57/127 (44%), Gaps = 10/127 (7%)

Query: 31   RLQAEELGDGCGHLVTYQDS---GTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGD- 86
            +++ E     CG  V   D+   G +TS N+P  YP H  C   +  P   R+ L+  D 
Sbjct: 2207 KIKYEAKSLACGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDR 2266

Query: 87   LDIE-SQTCASDYLLFTSSSDQYGP----YCGSMTVPKELLLNTSEVTVRFESGSHISGR 141
             DIE +  C S+YL      D   P    +CG+ ++P     +   + +RF S +  +  
Sbjct: 2267 FDIEVTPNCTSNYLELRDGVDSDAPILSKFCGT-SLPSSQWSSGEVMYLRFRSDNSPTHV 2325

Query: 142  GFLLTYA 148
            GF   Y+
Sbjct: 2326 GFKAKYS 2332



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 29/111 (26%), Positives = 50/111 (45%), Gaps = 8/111 (7%)

Query: 40   GCGHLVTYQDSGTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGDLDIESQT-CASDY 98
            GCG  ++   +G+ +S  +P  YP +  C   I    G  + L + D D+E  + C  D 
Sbjct: 1390 GCGGELSGA-TGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDV 1448

Query: 99   LLFTSSSDQYGPYCGSMTV------PKELLLNTSEVTVRFESGSHISGRGF 143
            L      D + P    +        P ++    +E+ +RF++   I+GRGF
Sbjct: 1449 LEIYGGPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGF 1499



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 31/105 (29%), Positives = 42/105 (40%), Gaps = 4/105 (3%)

Query: 47   YQDSGTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGDLDIE-SQTCASDYLLF---T 102
            Y   G   S  YP  YP +  C   I    G RL L      +E SQ C+ D++      
Sbjct: 1743 YMAEGIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLEDSQDCSRDFVEIREGN 1802

Query: 103  SSSDQYGPYCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTY 147
            ++    G YCG+        +    + VRF S    SG GF  T+
Sbjct: 1803 ATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATF 1847



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 25/100 (25%), Positives = 47/100 (47%), Gaps = 5/100 (5%)

Query: 49   DSGTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGDLDIESQ--TCASDYLLFTSSSD 106
            D GT TS N+P  YPN+  C   ITV  G+ + +   +  +E       +D+L       
Sbjct: 1055 DLGTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNFSLEEAIGNYYTDFLEIRDGGY 1114

Query: 107  QYGPYCG---SMTVPKELLLNTSEVTVRFESGSHISGRGF 143
            +  P  G      +P  ++ +++++ ++F+S    +  GF
Sbjct: 1115 EKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGF 1154



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 35/123 (28%), Positives = 53/123 (43%), Gaps = 10/123 (8%)

Query: 40   GCG-HLVTYQDSGTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGDLDIES----QTC 94
            GCG +L    ++      +  G Y  +  C   I  P  K + L      +E+    Q C
Sbjct: 3156 GCGGYLTGSNNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAASTRQRC 3215

Query: 95   ASDYL-LFTSSSDQY---GPYCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTYASS 150
              DY+ L+   S+     G +CGS TVP   + + + +TV+F S   +   GF  TY   
Sbjct: 3216 LYDYVKLYDGDSENANLAGTFCGS-TVPAPFISSGNFLTVQFISDLTLEREGFNATYTIM 3274

Query: 151  DHP 153
            D P
Sbjct: 3275 DMP 3277



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 31/115 (26%), Positives = 56/115 (48%), Gaps = 7/115 (6%)

Query: 41   CGHLVTYQDSGTMTSKNYPGT-YPNHTVCEKTITVPKGKRLILRLGDLDIESQT-CASDY 98
            CG  V  Q SG + S  +P   Y ++  CE  +    G  L +   D ++++ + C  D+
Sbjct: 2336 CGGRVPGQ-SGVVESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNSSGCEKDF 2394

Query: 99   LLFT---SSSDQYGPYCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTYASS 150
            +      +S +  G YCG+ T+P  +  +++   VRF +   ++  GF L + SS
Sbjct: 2395 VEIWDNHTSGNILGRYCGN-TIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESS 2448



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 31/121 (25%), Positives = 51/121 (42%), Gaps = 16/121 (13%)

Query: 41   CGHLVTYQDSGTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGD----LDIESQTCAS 96
            CG  + + D G +TS  YP TYP++  C   + V  G  + +         + +S     
Sbjct: 2092 CGGYL-HADRGIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQG 2150

Query: 97   DYLLFTSSSDQYGP----------YCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLT 146
            DYL+  +  D   P          +CGS      L  + +++ V+F S     G+GF + 
Sbjct: 2151 DYLVLRNGPDICSPPLGPPGGNGHFCGS-HASSTLFTSDNQMFVQFISDHSNEGQGFKIK 2209

Query: 147  Y 147
            Y
Sbjct: 2210 Y 2210



 Score = 37.0 bits (84), Expect = 0.046
 Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 1/71 (1%)

Query: 44   LVTYQDSGTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGDLDIESQ-TCASDYLLFT 102
            ++  Q  G + S  YP  Y  +  C  TI    G  +       D+E    C++DYL   
Sbjct: 1282 VIVNQTYGILESIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLEHHINCSTDYLELY 1341

Query: 103  SSSDQYGPYCG 113
                Q G YCG
Sbjct: 1342 DGPRQMGRYCG 1352



 Score = 36.2 bits (82), Expect = 0.078
 Identities = 33/115 (28%), Positives = 46/115 (40%), Gaps = 11/115 (9%)

Query: 40   GCGHLVTYQDSGTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGDLDIESQ-TCASDY 98
            GCG  +T   SGT  S NYP  Y + + C   +    G    L   D  +E    C  DY
Sbjct: 1164 GCGGNLT-TSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDFHLEHHPNCTLDY 1222

Query: 99   LLF----TSSSDQYGPYCGSMTVPKELLLNTS--EVTVRFESGSHISGRGFLLTY 147
            L      +S+S      CG    P   L+ +S   + ++  +     GRGF   Y
Sbjct: 1223 LAVYDGPSSNSHLLTQLCGDEKPP---LIRSSGDSMFIKLRTDEGQQGRGFKAEY 1274



 Score = 29.3 bits (64), Expect = 9.5
 Identities = 32/136 (23%), Positives = 54/136 (39%), Gaps = 12/136 (8%)

Query: 21   ALLLAVSAPLRLQAEELGDGCGHLVTYQDSGTMTSKNYPGTYPNHTVCEKTITVPKGKRL 80
            A+  +  AP +  +      CG   T   SG + S NYP  Y N+  C   I       +
Sbjct: 2900 AVFQSQEAPAQGFSASFVSRCGSNFT-GPSGYIISPNYPKQYDNNMNCTYVIEANPLSVV 2958

Query: 81   ILRLGDLDIESQ-----TCASDYLL----FTSSSDQYGPYCGSMTVPKELLLNTSEVTVR 131
            +L      +E++     +C +D +     ++  S  +   CG   +P  L +    V + 
Sbjct: 2959 LLTFVSFHLEARSAVTGSCVNDGVHIIRGYSVMSTPFATVCGD-EMPAPLTI-AGPVLLN 3016

Query: 132  FESGSHISGRGFLLTY 147
            F S   I+  GF  +Y
Sbjct: 3017 FYSNEQITDFGFKFSY 3032


>gi|21264363 mannan-binding lectin serine protease 2 isoform 1
           precursor [Homo sapiens]
          Length = 686

 Score = 65.9 bits (159), Expect = 9e-11
 Identities = 53/213 (24%), Positives = 95/213 (44%), Gaps = 25/213 (11%)

Query: 41  CGHLVTYQDSGTMTSKNYPGTYPNHTVCEKTITVPKGKRLILR-LGDLDIESQ---TCAS 96
           C   V  Q SG ++S  YP  YP  + C  +I++ +G  +IL  +   D+E+     C  
Sbjct: 184 CSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPY 243

Query: 97  DYLLFTSSSDQYGPYCGSMTVPKELLLNTSEVTVRF---ESGSHISGRGFLLTYASSDHP 153
           D+L   +  +++GP+CG  T+P  +   ++ VT+ F   ESG H    G+ + Y S+  P
Sbjct: 244 DFLKIQTDREEHGPFCGK-TLPHRIETKSNTVTITFVTDESGDH---TGWKIHYTSTAQP 299

Query: 154 DLITCLE--------RASHYLKTEYSKFCPAGCRDVAGDI------SGNMVDGYRDTSLL 199
                          +A + LK  +S FC  G   + G +      +    DG  D  + 
Sbjct: 300 CPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMP 359

Query: 200 CKAAIHAGIIADELGGQISVLQRKGISRYEGIL 232
             + +  G   D   G++  +   G++ Y+ ++
Sbjct: 360 ACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVI 392



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 30/111 (27%), Positives = 46/111 (41%), Gaps = 10/111 (9%)

Query: 51  GTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGDLDIE-SQTCASDYLLFTSSSDQYG 109
           G + S  +PG Y N      T+T P G RL L     D+E S  C  D++  +S +    
Sbjct: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87

Query: 110 PYCGSMTVPKE---------LLLNTSEVTVRFESGSHISGRGFLLTYASSD 151
             CG  +   E          L ++ ++T R +  +     GF   YA+ D
Sbjct: 88  TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAED 138


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,915,527
Number of Sequences: 37866
Number of extensions: 935732
Number of successful extensions: 2839
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 78
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 2461
Number of HSP's gapped (non-prelim): 284
length of query: 539
length of database: 18,247,518
effective HSP length: 107
effective length of query: 432
effective length of database: 14,195,856
effective search space: 6132609792
effective search space used: 6132609792
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.